IMP: Integrative Multi-species Prediction

Drosophila melanogaster

0 known processes

RnpS1 (Dmel_CG16788)

RNA-binding protein S1

(Aliases: Dmel\CG16788,DEK,CG16788,cg16788)

Entrez: 41147
FLYBASE: FBgn0037707
UniProtKB: Q9VHC0

Process Predictions
Disease Predictions

RnpS1 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
cell migration	GO:0016477	238	0.690
negative regulation of cellular metabolic process	GO:0031324	382	0.545	Human
regulation of meiosis	GO:0040020	3	0.476	Worm
mrna metabolic process	GO:0016071	124	0.439	Human
cell motility	GO:0048870	251	0.413
localization of cell	GO:0051674	257	0.329
positive regulation of cellular component organization	GO:0051130	156	0.286
macromolecular complex assembly	GO:0065003	256	0.245
regulation of organelle organization	GO:0033043	196	0.240	Worm
nuclear division	GO:0000280	332	0.239	Worm
regulation of cell cycle	GO:0051726	291	0.235	Worm
organonitrogen compound metabolic process	GO:1901564	318	0.222
posttranscriptional regulation of gene expression	GO:0010608	145	0.219
cell proliferation	GO:0008283	299	0.217	Worm
negative regulation of rna biosynthetic process	GO:1902679	240	0.215
chromosome organization	GO:0051276	360	0.215
protein localization	GO:0008104	284	0.197
negative regulation of biosynthetic process	GO:0009890	277	0.189
organic substance transport	GO:0071702	257	0.186
chromatin remodeling	GO:0006338	72	0.165
regulation of rna splicing	GO:0043484	69	0.164	Human
protein complex assembly	GO:0006461	200	0.162
regulation of protein metabolic process	GO:0051246	256	0.157
rna splicing via transesterification reactions	GO:0000375	73	0.152	Human
negative regulation of cellular biosynthetic process	GO:0031327	277	0.130
regulation of cellular protein metabolic process	GO:0032268	243	0.130
nucleobase containing small molecule metabolic process	GO:0055086	174	0.129
rna processing	GO:0006396	147	0.126	Human
protein complex biogenesis	GO:0070271	201	0.126
regulation of cell proliferation	GO:0042127	163	0.123	Worm
dna templated transcription elongation	GO:0006354	18	0.123
mitotic spindle organization	GO:0007052	220	0.116
mrna splicing via spliceosome	GO:0000398	73	0.113	Human
regulation of cellular ketone metabolic process	GO:0010565	3	0.109
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.103
organic substance catabolic process	GO:1901575	308	0.102	Human
response to temperature stimulus	GO:0009266	106	0.100
cellular macromolecular complex assembly	GO:0034622	153	0.100
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.100
negative regulation of signaling	GO:0023057	219	0.096
vesicle mediated transport	GO:0016192	381	0.095
regulation of localization	GO:0032879	275	0.094
transcription from rna polymerase ii promoter	GO:0006366	368	0.092
regulation of cell division	GO:0051302	72	0.092	Worm
protein modification process	GO:0036211	438	0.091
cellular macromolecule localization	GO:0070727	220	0.090
sex differentiation	GO:0007548	81	0.090
glycosyl compound catabolic process	GO:1901658	112	0.090
intracellular signal transduction	GO:0035556	300	0.089
endocytosis	GO:0006897	310	0.087
negative regulation of signal transduction	GO:0009968	206	0.082
cellular protein modification process	GO:0006464	438	0.079
rna splicing via transesterification reactions with bulged adenosine as nucleophile	GO:0000377	73	0.078	Human
positive regulation of protein metabolic process	GO:0051247	128	0.078
establishment of localization in cell	GO:0051649	402	0.077
regulation of mrna splicing via spliceosome	GO:0048024	64	0.076	Human
cytoskeleton dependent cytokinesis	GO:0061640	81	0.068
regulation of phosphorus metabolic process	GO:0051174	210	0.067
response to organic substance	GO:0010033	284	0.066
purine nucleoside triphosphate metabolic process	GO:0009144	119	0.066
spindle organization	GO:0007051	253	0.065
covalent chromatin modification	GO:0016569	106	0.064
small molecule metabolic process	GO:0044281	305	0.063
cellular catabolic process	GO:0044248	372	0.062	Human
larval development	GO:0002164	104	0.062	Worm
chromatin organization	GO:0006325	207	0.060
protein modification by small protein conjugation or removal	GO:0070647	106	0.059
proteolysis	GO:0006508	192	0.059
single organism catabolic process	GO:0044712	228	0.059
mitotic nuclear division	GO:0007067	213	0.058
molting cycle	GO:0042303	56	0.057
cell division	GO:0051301	248	0.054	Worm
cell cycle checkpoint	GO:0000075	95	0.054
rna localization	GO:0006403	115	0.053
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.053	Human
actin filament based process	GO:0030029	220	0.053
reproductive system development	GO:0061458	74	0.052
embryo development ending in birth or egg hatching	GO:0009792	152	0.050	Worm
organic cyclic compound catabolic process	GO:1901361	168	0.049	Human
cell cycle phase transition	GO:0044770	140	0.049
catabolic process	GO:0009056	409	0.048	Human
negative regulation of rna metabolic process	GO:0051253	251	0.048	Human
positive regulation of phosphate metabolic process	GO:0045937	139	0.048
regulation of molecular function	GO:0065009	217	0.048
nucleotide metabolic process	GO:0009117	161	0.048
organelle fission	GO:0048285	340	0.048	Worm
intracellular transport	GO:0046907	228	0.048
negative regulation of neurotransmitter secretion	GO:0046929	2	0.047
mrna catabolic process	GO:0006402	33	0.047	Human
nucleobase containing compound catabolic process	GO:0034655	165	0.046	Human
negative regulation of cell communication	GO:0010648	223	0.045
negative regulation of response to stimulus	GO:0048585	258	0.045
rna splicing	GO:0008380	83	0.045	Human
purine ribonucleotide catabolic process	GO:0009154	109	0.045
cellular protein localization	GO:0034613	160	0.045
nucleoside triphosphate catabolic process	GO:0009143	108	0.044
cellular response to dna damage stimulus	GO:0006974	223	0.043
negative regulation of gene expression	GO:0010629	387	0.043	Human
establishment of protein localization	GO:0045184	163	0.043
ribonucleotide metabolic process	GO:0009259	145	0.042
programmed cell death	GO:0012501	257	0.042	Human
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.042
chromatin modification	GO:0016568	147	0.042
nucleoside phosphate metabolic process	GO:0006753	162	0.041
regulation of response to stress	GO:0080134	200	0.041
ribonucleotide catabolic process	GO:0009261	109	0.041
purine containing compound metabolic process	GO:0072521	155	0.040
negative regulation of cell cycle	GO:0045786	116	0.039
regulation of phosphate metabolic process	GO:0019220	210	0.039
ribonucleoside triphosphate metabolic process	GO:0009199	119	0.038
regulation of gene expression epigenetic	GO:0040029	128	0.038
nucleosome organization	GO:0034728	59	0.038
rna catabolic process	GO:0006401	37	0.038	Human
single organism intracellular transport	GO:1902582	207	0.037
purine containing compound catabolic process	GO:0072523	112	0.037
positive regulation of molecular function	GO:0044093	136	0.037
purine ribonucleoside metabolic process	GO:0046128	127	0.037
purine nucleotide metabolic process	GO:0006163	146	0.036
regionalization	GO:0003002	416	0.036
negative regulation of cell cycle process	GO:0010948	109	0.036
regulation of cell cycle process	GO:0010564	181	0.036	Worm
mitotic cell cycle checkpoint	GO:0007093	88	0.035
response to oxygen containing compound	GO:1901700	200	0.035
cell death	GO:0008219	279	0.035	Human
mrna cis splicing via spliceosome	GO:0045292	1	0.035
nitrogen compound transport	GO:0071705	85	0.034
regulation of nuclear division	GO:0051783	58	0.033	Worm
regulation of cellular component biogenesis	GO:0044087	201	0.033
positive regulation of cellular component biogenesis	GO:0044089	80	0.032
reproductive structure development	GO:0048608	74	0.031
ribose phosphate metabolic process	GO:0019693	145	0.031
regulation of mitotic cell cycle	GO:0007346	190	0.031
aromatic compound catabolic process	GO:0019439	166	0.030	Human
cellular protein complex assembly	GO:0043623	71	0.030
cell chemotaxis involved in malpighian tubule morphogenesis	GO:0061352	3	0.029
transcription elongation from rna polymerase ii promoter	GO:0006368	18	0.029
purine nucleoside metabolic process	GO:0042278	127	0.028
heterocycle catabolic process	GO:0046700	166	0.028	Human
single organism cellular localization	GO:1902580	180	0.028
positive regulation of phosphorus metabolic process	GO:0010562	139	0.027
dna conformation change	GO:0071103	105	0.027
negative regulation of transcription dna templated	GO:0045892	237	0.027
nucleotide catabolic process	GO:0009166	109	0.027
negative regulation of mitotic cell cycle	GO:0045930	109	0.026
gonad development	GO:0008406	50	0.026
positive regulation of signal transduction	GO:0009967	223	0.026
regulation of intracellular signal transduction	GO:1902531	236	0.026
cellular amine metabolic process	GO:0044106	12	0.026
cellular amino acid metabolic process	GO:0006520	61	0.026
purine nucleoside triphosphate catabolic process	GO:0009146	108	0.025
positive regulation of cellular protein metabolic process	GO:0032270	118	0.025
organonitrogen compound catabolic process	GO:1901565	128	0.025
regulation of syncytial blastoderm mitotic cell cycle	GO:0007348	4	0.025
development of primary sexual characteristics	GO:0045137	50	0.025
regulation of protein modification process	GO:0031399	112	0.025
left right axis specification	GO:0070986	1	0.024
carbohydrate derivative metabolic process	GO:1901135	217	0.024
regulation of dna templated transcription elongation	GO:0032784	17	0.024
formation of a compartment boundary	GO:0060288	4	0.024
purine ribonucleoside triphosphate catabolic process	GO:0009207	108	0.024
ras protein signal transduction	GO:0007265	88	0.024
cytoplasmic transport	GO:0016482	130	0.023
dna metabolic process	GO:0006259	227	0.023
regulation of growth	GO:0040008	233	0.023
cellular macromolecule catabolic process	GO:0044265	136	0.023	Human
regulation of catalytic activity	GO:0050790	185	0.023
positive regulation of organelle organization	GO:0010638	65	0.023
nucleoside phosphate catabolic process	GO:1901292	110	0.023
male gamete generation	GO:0048232	201	0.023
cellular nitrogen compound catabolic process	GO:0044270	165	0.022	Human
organelle inheritance	GO:0048308	2	0.022
positive regulation of ribosome biogenesis	GO:0090070	3	0.022
negative regulation of nucleoside metabolic process	GO:0045978	1	0.022
positive regulation of cellular amino acid metabolic process	GO:0045764	0	0.021
anatomical structure homeostasis	GO:0060249	97	0.021
small gtpase mediated signal transduction	GO:0007264	88	0.021
intermediate filament based process	GO:0045103	1	0.021
glycosyl compound metabolic process	GO:1901657	127	0.021
phagocytosis	GO:0006909	215	0.021
nucleoside metabolic process	GO:0009116	127	0.020
regulation of wnt signaling pathway	GO:0030111	68	0.020
regulation of protein localization	GO:0032880	76	0.020
dna damage checkpoint	GO:0000077	78	0.020
regulation of translation	GO:0006417	56	0.020
mitotic g2 m transition checkpoint	GO:0044818	70	0.019
nucleoside catabolic process	GO:0009164	112	0.019
dna integrity checkpoint	GO:0031570	81	0.019
regulation of proteolysis	GO:0030162	87	0.019
regulation of rac gtpase activity	GO:0032314	1	0.019
meiotic cell cycle	GO:0051321	171	0.019	Worm
secretion by cell	GO:0032940	101	0.019
regulation of multicellular organismal development	GO:2000026	414	0.019
amine metabolic process	GO:0009308	12	0.019
organophosphate metabolic process	GO:0019637	195	0.019
body morphogenesis	GO:0010171	2	0.019
regulation of mitotic cell cycle phase transition	GO:1901990	130	0.019
regulation of cellular amine metabolic process	GO:0033238	3	0.019
purine ribonucleotide metabolic process	GO:0009150	145	0.019
organophosphate catabolic process	GO:0046434	112	0.018
positive regulation of cell communication	GO:0010647	250	0.018
negative regulation of multicellular organismal process	GO:0051241	142	0.018
mrna processing	GO:0006397	104	0.018	Human
alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor clustering	GO:0097113	2	0.017
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	119	0.017
regulation of small gtpase mediated signal transduction	GO:0051056	93	0.017
septin cytoskeleton organization	GO:0032185	1	0.017
regulation of cellular amino acid metabolic process	GO:0006521	0	0.017
regulation of meiotic cell cycle	GO:0051445	9	0.017	Worm
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.017
positive regulation of signaling	GO:0023056	243	0.016
purine nucleotide catabolic process	GO:0006195	109	0.016
photoreceptor cell differentiation	GO:0046530	170	0.016
regulation of ras protein signal transduction	GO:0046578	93	0.016
homeostatic process	GO:0042592	199	0.016
blastoderm segmentation	GO:0007350	159	0.016
regulation of mrna metabolic process	GO:1903311	72	0.016	Human
posttranscriptional gene silencing	GO:0016441	46	0.016
positive regulation of response to stimulus	GO:0048584	323	0.016
establishment or maintenance of polarity of larval imaginal disc epithelium	GO:0016336	3	0.016
establishment of protein localization to organelle	GO:0072594	62	0.016
cellular response to organic substance	GO:0071310	132	0.016
negative regulation of transcription factor import into nucleus	GO:0042992	4	0.016
dorsal vessel heart proper cell fate commitment	GO:0035053	2	0.016
purine nucleoside catabolic process	GO:0006152	112	0.016
immune system process	GO:0002376	347	0.015
actin cytoskeleton organization	GO:0030036	206	0.015
ribonucleoside triphosphate catabolic process	GO:0009203	108	0.015
modification dependent macromolecule catabolic process	GO:0043632	79	0.015
response to external biotic stimulus	GO:0043207	293	0.015
regulation of anatomical structure morphogenesis	GO:0022603	242	0.015
protein neddylation	GO:0045116	5	0.015
eye development	GO:0001654	323	0.015
receptor mediated endocytosis	GO:0006898	21	0.015
response to organic cyclic compound	GO:0014070	89	0.015
asymmetric neuroblast division resulting in ganglion mother cell formation	GO:0055060	2	0.014
regulation of striated muscle contraction	GO:0006942	2	0.014
chromosome segregation	GO:0007059	157	0.014
regulation of cell differentiation	GO:0045595	302	0.014
positive regulation of intracellular signal transduction	GO:1902533	116	0.014
negative regulation of intrinsic apoptotic signaling pathway	GO:2001243	1	0.014
imaginal disc derived wing morphogenesis	GO:0007476	337	0.014
internal protein amino acid acetylation	GO:0006475	38	0.014
negative regulation of developmental pigmentation	GO:0048086	1	0.014
regulation of protein catabolic process	GO:0042176	55	0.014
multicellular organismal aging	GO:0010259	140	0.014
carbohydrate derivative catabolic process	GO:1901136	118	0.013
regulation of reactive oxygen species biosynthetic process	GO:1903426	0	0.013
regulation of cellular localization	GO:0060341	136	0.013
histone modification	GO:0016570	106	0.013
positive regulation of binding	GO:0051099	4	0.013
genitalia development	GO:0048806	26	0.013
meiotic nuclear envelope disassembly	GO:0051078	2	0.013
spermatogenesis	GO:0007283	200	0.013
positive regulation of macromolecule metabolic process	GO:0010604	405	0.013
nucleobase containing compound transport	GO:0015931	56	0.013
mitotic g2 dna damage checkpoint	GO:0007095	69	0.013
peptidyl amino acid modification	GO:0018193	105	0.013
purine ribonucleoside catabolic process	GO:0046130	112	0.013
embryonic pattern specification	GO:0009880	174	0.013
proteolysis involved in cellular protein catabolic process	GO:0051603	83	0.013
alternative mrna splicing via spliceosome	GO:0000380	60	0.012	Human
negative regulation of compound eye photoreceptor development	GO:0045316	3	0.012
protein phosphorylation	GO:0006468	169	0.012
regulation of locomotion	GO:0040012	42	0.012
phosphorylation	GO:0016310	294	0.012
regulation of cell cycle phase transition	GO:1901987	130	0.012
regulation of rap gtpase activity	GO:0032317	3	0.012
cytokinesis	GO:0000910	90	0.012
negative regulation of cell cycle phase transition	GO:1901988	103	0.012
cell adhesion	GO:0007155	136	0.012
peptidyl lysine acetylation	GO:0018394	39	0.012
phospholipid transport	GO:0015914	2	0.012
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.012
sister chromatid segregation	GO:0000819	92	0.012
negative regulation of eye photoreceptor cell development	GO:0042480	3	0.012
organelle assembly	GO:0070925	198	0.012
cellular ketone metabolic process	GO:0042180	24	0.012
ribonucleoside catabolic process	GO:0042454	112	0.012
ribonucleoside metabolic process	GO:0009119	127	0.012
protein transport	GO:0015031	155	0.011
positive regulation of neuron projection regeneration	GO:0070572	3	0.011
dendrite regeneration	GO:0031104	2	0.011
protein localization to organelle	GO:0033365	82	0.011
spliceosomal complex assembly	GO:0000245	1	0.011
positive regulation of stem cell maintenance	GO:1902459	1	0.011
regulation of programmed cell death	GO:0043067	152	0.011	Human
negative regulation of protein metabolic process	GO:0051248	85	0.011
ameboidal type cell migration	GO:0001667	151	0.011
ovulation cycle	GO:0042698	1	0.011
border follicle cell delamination	GO:0030709	3	0.011
aging	GO:0007568	143	0.011
regulation of cellular catabolic process	GO:0031329	157	0.011
nucleoside triphosphate metabolic process	GO:0009141	120	0.011
positive regulation of intracellular transport	GO:0032388	42	0.011
regulation of intracellular protein transport	GO:0033157	46	0.011
sensory organ morphogenesis	GO:0090596	260	0.011
response to heat	GO:0009408	63	0.011
translation	GO:0006412	69	0.010
negative regulation of gene expression epigenetic	GO:0045814	77	0.010
regulation of chromosome organization	GO:0033044	64	0.010
appendage morphogenesis	GO:0035107	397	0.010
zygotic specification of dorsal ventral axis	GO:0007352	3	0.010
cellular response to nutrient	GO:0031670	1	0.010
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.010

RnpS1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.037
disease of cellular proliferation	DOID:14566	0.012
benign neoplasm	DOID:0060072	0.012
respiratory system cancer	DOID:0050615	0.011
cancer	DOID:162	0.011
organ system cancer	DOID:0050686	0.011
connective tissue disease	DOID:65	0.011
brachydactyly	DOID:0050581	0.011
musculoskeletal system disease	DOID:17	0.011
dysostosis	DOID:1934	0.011
bone development disease	DOID:0080006	0.011
bone disease	DOID:0080001	0.011

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