Drosophila melanogaster

227 known processes

skpA (Dmel_CG16983)

CG16983 gene product from transcript CG16983-RD

(Aliases: CG16983,l(1)G0037,Skp,dSkp-1,Skp1,l(1)G0058,l(1)G0109,Dmel\CG16983,dskpA,dSkpA,l(1)G0389,anon-WO03040301.238,SkpA,anon-WO03040301.236,anon-WO03040301.234,EG:115C2.4,spkA)

skpA biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
negative regulation of cell cycleGO:00457861160.995
cellular response to dna damage stimulusGO:00069742230.991
protein modification by small protein conjugation or removalGO:00706471060.989
Human
synapse organizationGO:00508081960.982
negative regulation of neuroblast proliferationGO:0007406270.973
dna integrity checkpointGO:0031570810.967
regulation of cell cycle phase transitionGO:19019871300.967
protein ubiquitinationGO:0016567700.963
Human
organelle fissionGO:00482853400.956
dna replicationGO:0006260480.946
negative regulation of cell cycle phase transitionGO:19019881030.943
developmental maturationGO:00217001720.931
vesicle mediated transportGO:00161923810.929
Worm
mitotic g2 dna damage checkpointGO:0007095690.913
regulation of cellular component biogenesisGO:00440872010.907
meiotic cell cycleGO:00513211710.903
Worm
apoptotic processGO:00069151590.886
single organism intracellular transportGO:19025822070.883
cell cycle phase transitionGO:00447701400.882
cell maturationGO:00484691440.871
negative regulation of synaptic growth at neuromuscular junctionGO:0045886390.861
mitotic cell cycle phase transitionGO:00447721380.861
mitotic cell cycle checkpointGO:0007093880.855
regulation of phosphate metabolic processGO:00192202100.854
regulation of protein stabilityGO:0031647430.839
regulation of response to stressGO:00801342000.839
negative regulation of neural precursor cell proliferationGO:2000178270.837
negative regulation of nervous system developmentGO:0051961920.828
dna conformation changeGO:00711031050.800
dna packagingGO:0006323910.784
negative regulation of cell cycle processGO:00109481090.778
jnk cascadeGO:0007254500.774
deathGO:00162652840.769
intracellular transportGO:00469072280.752
axonogenesisGO:00074092900.750
cellular protein modification processGO:00064644380.741
Human
negative regulation of mitotic cell cycle phase transitionGO:19019911030.740
protein catabolic processGO:00301631010.739
Human
regulation of mitotic cell cycle phase transitionGO:19019901300.729
mitotic dna integrity checkpointGO:0044774750.721
neuron remodelingGO:0016322290.719
dna damage checkpointGO:0000077780.702
regulation of cell cycle processGO:00105641810.697
negative regulation of response to stimulusGO:00485852580.688
modification dependent protein catabolic processGO:0019941780.685
Human
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161540.675
Human
stress activated mapk cascadeGO:0051403520.663
chromosome organizationGO:00512763600.658
regulation of cytoskeleton organizationGO:0051493890.653
regulation of cellular response to stressGO:0080135890.652
negative regulation of mitotic cell cycleGO:00459301090.616
programmed cell deathGO:00125012570.567
developmental growthGO:00485892800.553
cell deathGO:00082192790.535
positive regulation of cellular biosynthetic processGO:00313283160.508
negative regulation of developmental processGO:00510932010.488
response to organonitrogen compoundGO:0010243750.486
stress activated protein kinase signaling cascadeGO:0031098550.477
synaptic growth at neuromuscular junctionGO:00511241190.472
cellular protein catabolic processGO:0044257830.469
Human
neuromuscular junction developmentGO:00075281490.468
regulation of synaptic growth at neuromuscular junctionGO:0008582890.456
cellular response to endogenous stimulusGO:0071495800.441
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.434
growthGO:00400073590.433
endocytosisGO:00068973100.422
Worm
regulation of cellular protein metabolic processGO:00322682430.411
response to endogenous stimulusGO:00097191190.409
cellular macromolecule catabolic processGO:00442651360.401
Human
regulation of synapse assemblyGO:0051963940.399
regulation of stress activated protein kinase signaling cascadeGO:0070302420.398
regulation of jnk cascadeGO:0046328400.396
meiotic nuclear divisionGO:00071261510.393
Worm
regulation of cell deathGO:00109411730.386
positive regulation of response to stimulusGO:00485843230.373
negative regulation of multicellular organismal processGO:00512411420.372
cellular response to chemical stimulusGO:00708871990.370
dna repairGO:0006281540.364
regionalizationGO:00030024160.353
negative regulation of programmed cell deathGO:0043069720.343
posttranscriptional regulation of gene expressionGO:00106081450.338
chromatin assembly or disassemblyGO:0006333520.335
defense response to gram negative bacteriumGO:0050829940.326
Worm
regulation of protein modification processGO:00313991120.318
protein modification by small protein conjugationGO:0032446790.313
Human
regulation of developmental growthGO:00486381740.307
neuron maturationGO:0042551310.298
proteolysis involved in cellular protein catabolic processGO:0051603830.290
Human
centrosome duplicationGO:00512981210.284
segmentationGO:00352822070.282
mitotic dna damage checkpointGO:0044773740.276
negative regulation of signal transductionGO:00099682060.270
modification dependent macromolecule catabolic processGO:0043632790.262
Human
negative regulation of stem cell proliferationGO:2000647300.257
response to external biotic stimulusGO:00432072930.251
Worm
response to other organismGO:00517072930.248
Worm
regulation of innate immune responseGO:0045088710.240
regulation of programmed cell deathGO:00430671520.239
regulation of mapk cascadeGO:0043408920.239
response to bacteriumGO:00096171980.231
Worm
regulation of stem cell proliferationGO:0072091400.225
regulation of synapse organizationGO:00508071100.224
ubiquitin dependent protein catabolic processGO:0006511780.223
Human
negative regulation of synapse assemblyGO:0051964390.220
phagocytosisGO:00069092150.220
columnar cuboidal epithelial cell developmentGO:00020662490.219
axon guidanceGO:00074112330.206
macromolecular complex assemblyGO:00650032560.203
negative regulation of stress activated protein kinase signaling cascadeGO:0070303200.198
embryonic pattern specificationGO:00098801740.197
regulation of mitotic cell cycleGO:00073461900.191
positive regulation of macromolecule metabolic processGO:00106044050.186
cytoplasmic transportGO:00164821300.182
protein localization to plasma membraneGO:0072659130.180
protein modification processGO:00362114380.178
Human
axis specificationGO:00097981670.168
response to biotic stimulusGO:00096072940.166
Worm
positive regulation of nucleobase containing compound metabolic processGO:00459353320.161
macromolecule catabolic processGO:00090571610.156
Human
larval developmentGO:00021641040.152
Worm
regulation of protein modification by small protein conjugation or removalGO:1903320250.152
cellular response to insulin stimulusGO:0032869280.151
organic substance catabolic processGO:19015753080.150
Human
transcription from rna polymerase ii promoterGO:00063663680.149
negative regulation of phosphorus metabolic processGO:0010563450.149
negative regulation of cell deathGO:0060548810.137
tissue migrationGO:00901301550.136
nuclear divisionGO:00002803320.130
establishment of localization in cellGO:00516494020.127
Worm
regulation of cysteine type endopeptidase activityGO:2000116270.124
spermatogenesisGO:00072832000.117
synapse assemblyGO:00074161430.116
negative regulation of apoptotic processGO:0043066630.113
regulation of phosphorus metabolic processGO:00511742100.111
response to nitrogen compoundGO:1901698900.110
cellular response to organic substanceGO:00713101320.109
regulation of cell cycleGO:00517262910.108
histone h4 k20 methylationGO:003477040.107
response to organic substanceGO:00100332840.106
axon developmentGO:00615642970.106
male gamete generationGO:00482322010.106
mitochondrion organizationGO:0007005650.106
spindle organizationGO:00070512530.104
negative regulation of cell communicationGO:00106482230.103
histone modificationGO:00165701060.102
Human
muscle structure developmentGO:00610612240.099
negative regulation of cellular metabolic processGO:00313243820.099
positive regulation of signal transductionGO:00099672230.097
protein acylationGO:0043543420.096
positive regulation of nitrogen compound metabolic processGO:00511733540.095
salivary gland morphogenesisGO:00074351450.090
regulation of multicellular organismal developmentGO:20000264140.088
insulin receptor signaling pathwayGO:0008286250.088
ncrna metabolic processGO:0034660430.087
cellular amine metabolic processGO:0044106120.086
gland morphogenesisGO:00226121450.085
positive regulation of rna metabolic processGO:00512542710.084
regulation of neuroblast proliferationGO:1902692340.082
nuclear transportGO:0051169720.082
signal transduction by phosphorylationGO:00230141070.081
intracellular signal transductionGO:00355563000.081
regulation of apoptotic processGO:00429811300.081
tissue deathGO:00162711020.079
regulation of stress activated mapk cascadeGO:0032872410.078
regulation of catalytic activityGO:00507901850.077
nucleocytoplasmic transportGO:0006913720.076
scf dependent proteasomal ubiquitin dependent protein catabolic processGO:003114610.076
Human
positive regulation of cellular protein metabolic processGO:00322701180.076
positive regulation of biosynthetic processGO:00098913160.076
negative regulation of phosphate metabolic processGO:0045936450.076
cellular protein localizationGO:00346131600.074
regulation of defense responseGO:00313471020.074
cell cycle dna replicationGO:0044786230.073
cellular macromolecular complex assemblyGO:00346221530.071
dna metabolic processGO:00062592270.071
maintenance of locationGO:0051235730.070
salivary gland cell autophagic cell deathGO:0035071830.069
cellular macromolecule localizationGO:00707272200.067
regulation of notch signaling pathwayGO:00085931000.067
response to peptideGO:1901652290.067
anterior posterior pattern specificationGO:00099521360.066
cell divisionGO:00513012480.065
positive regulation of immune responseGO:0050778630.064
circulatory system developmentGO:0072359820.064
organophosphate metabolic processGO:00196371950.064
positive regulation of cell cycleGO:0045787430.061
neuron projection guidanceGO:00974852410.061
developmental programmed cell deathGO:00106231380.060
catabolic processGO:00090564090.059
Human
exocrine system developmentGO:00352721620.058
response to oxygen containing compoundGO:19017002000.057
dna endoreduplicationGO:0042023220.056
regulation of transferase activityGO:0051338580.055
cellular amide metabolic processGO:0043603800.054
mitotic g2 m transition checkpointGO:0044818700.054
negative regulation of signalingGO:00230572190.053
cell cycle checkpointGO:0000075950.053
negative regulation of developmental growthGO:0048640640.053
taxisGO:00423303040.053
regulation of nervous system developmentGO:00519602480.051
defense response to bacteriumGO:00427421780.051
Worm
cellular response to peptideGO:1901653280.051
cytokinesisGO:0000910900.050
transmembrane transportGO:00550851390.049
mitotic nuclear divisionGO:00070672130.047
regulation of wnt signaling pathwayGO:0030111680.047
regulation of production of molecular mediator of immune responseGO:0002700440.046
trna modificationGO:000640020.046
regulation of cellular localizationGO:00603411360.044
regulation of transcription from rna polymerase ii promoterGO:00063573780.044
positive regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032436190.043
salivary gland developmentGO:00074311620.042
wnt signaling pathwayGO:0016055980.042
proteasomal protein catabolic processGO:0010498590.042
Human
enzyme linked receptor protein signaling pathwayGO:00071671790.042
cell motilityGO:00488702510.039
Worm
positive regulation of defense responseGO:0031349590.039
covalent chromatin modificationGO:00165691060.038
Human
body morphogenesisGO:001017120.038
regulation of proteolysisGO:0030162870.038
immune responseGO:00069552460.038
Worm
rna processingGO:00063961470.036
negative regulation of phosphorylationGO:0042326350.035
cell migrationGO:00164772380.035
Worm
stem cell differentiationGO:00488631170.035
embryo development ending in birth or egg hatchingGO:00097921520.034
Worm
regulation of growthGO:00400082330.034
negative regulation of cellular component organizationGO:00511291080.033
appendage developmentGO:00487364010.033
regulation of cell proliferationGO:00421271630.033
Worm
receptor mediated endocytosisGO:0006898210.033
Worm
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052240.033
protein maturationGO:0051604710.033
mapk cascadeGO:00001651070.032
development of primary sexual characteristicsGO:0045137500.032
Worm
sensory organ precursor cell divisionGO:0045035100.031
agingGO:00075681430.031
Worm
lipid localizationGO:0010876540.031
negative regulation of neurogenesisGO:0050768530.031
positive regulation of cell communicationGO:00106472500.031
ovarian follicle cell developmentGO:00307072480.030
positive regulation of protein metabolic processGO:00512471280.029
regulation of protein ubiquitinationGO:0031396220.029
epithelial cell differentiationGO:00308553220.029
establishment of oocyte nucleus localization involved in oocyte dorsal ventral axis specificationGO:003072260.029
regulation of microtubule based processGO:0032886490.029
regulation of synapse structure and activityGO:00508031280.029
regulation of molecular functionGO:00650092170.028
pigment metabolic processGO:0042440840.028
protein processingGO:0016485680.028
positive regulation of proteasomal protein catabolic processGO:1901800200.028
centrosome cycleGO:00070981370.028
negative regulation of proteolysisGO:0045861310.027
organic substance transportGO:00717022570.027
ribosomal large subunit biogenesisGO:004227310.027
positive regulation of rna biosynthetic processGO:19026802660.026
autophagic cell deathGO:0048102830.026
dorsal ventral pattern formationGO:00099531330.026
negative regulation of defense responseGO:0031348350.025
regulation of response to external stimulusGO:00321011150.025
chromosome segregationGO:00070591570.025
Worm
neural precursor cell proliferationGO:0061351750.025
dendrite developmentGO:00163582040.025
regulation of organelle organizationGO:00330431960.024
positive regulation of multi organism processGO:0043902400.024
regulation of nucleocytoplasmic transportGO:0046822350.024
protein localization to membraneGO:0072657190.024
regulation of gene silencingGO:0060968630.023
positive regulation of phosphorus metabolic processGO:00105621390.023
phosphorylationGO:00163102940.023
chromatin modificationGO:00165681470.023
Human
cellular response to hormone stimulusGO:0032870440.023
negative regulation of protein processingGO:0010955310.022
positive regulation of phosphate metabolic processGO:00459371390.022
regulation of multi organism processGO:00439001310.022
positive regulation of nucleic acid templated transcriptionGO:19035082660.022
mitotic spindle organizationGO:00070522200.022
blastoderm segmentationGO:00073501590.022
membrane organizationGO:00610241120.022
regulation of neural precursor cell proliferationGO:2000177350.021
autophagic vacuole assemblyGO:000004520.021
telomere cappingGO:0016233110.021
metal ion transportGO:0030001740.020
positive regulation of signalingGO:00230562430.020
regulation of cellular amine metabolic processGO:003323830.020
regulation of hemocyte proliferationGO:0035206370.020
positive regulation of response to external stimulusGO:0032103440.020
imaginal disc fusionGO:0046528190.019
positive regulation of heterochromatin assemblyGO:003145350.019
regulation of protein catabolic processGO:0042176550.019
positive regulation of cell sizeGO:0045793210.019
positive regulation of wnt signaling pathwayGO:0030177250.019
skeletal muscle tissue developmentGO:0007519130.019
ribosome biogenesisGO:004225480.019
pigmentationGO:0043473750.018
positive regulation of gene expressionGO:00106282900.018
epithelial cell proliferationGO:0050673150.018
oocyte differentiationGO:00099941450.018
positive regulation of protein modification processGO:0031401580.018
negative regulation of protein maturationGO:1903318310.018
positive regulation of transcription dna templatedGO:00458932660.018
cell proliferationGO:00082832990.017
Worm
tripartite regional subdivisionGO:00073511030.017
female meiotic divisionGO:0007143700.017
dorsal ventral axis specificationGO:0009950660.017
protein phosphorylationGO:00064681690.017
regulation of anatomical structure sizeGO:00900661630.017
response to radiationGO:00093141550.016
appendage morphogenesisGO:00351073970.016
cellular response to nitrogen compoundGO:1901699510.016
regulation of heterochromatin assemblyGO:003144580.016
chromatin organizationGO:00063252070.016
Human
oocyte developmentGO:00485991240.016
immune effector processGO:0002252980.016
cellular response to abiotic stimulusGO:0071214580.016
regulation of intracellular signal transductionGO:19025312360.015
regulation of peptidase activityGO:0052547390.015
single organism behaviorGO:00447083910.015
nitric oxide metabolic processGO:004620910.015
single organism cellular localizationGO:19025801800.015
Worm
establishment of protein localizationGO:00451841630.015
positive regulation of immune system processGO:0002684680.015
cellular ion homeostasisGO:0006873390.015
positive regulation of intracellular signal transductionGO:19025331160.015
histolysisGO:00075591020.015
regulation of chromatin assemblyGO:001084790.014
gland developmentGO:00487321910.014
multicellular organismal agingGO:00102591400.014
Worm
regulation of proteolysis involved in cellular protein catabolic processGO:1903050440.014
regulation of immune responseGO:00507761180.014
negative regulation of growthGO:0045926840.014
limb developmentGO:006017310.014
regulation of cellular ketone metabolic processGO:001056530.014
instar larval developmentGO:0002168550.014
negative regulation of peptidase activityGO:0010466110.013
positive regulation of cellular protein catabolic processGO:1903364240.013
ncrna processingGO:0034470300.013
regulation of cytoplasmic transportGO:1903649470.013
melanin metabolic processGO:0006582470.013
notch signaling pathwayGO:00072191200.013
regulation of intracellular transportGO:0032386640.013
regulation of catabolic processGO:00098941700.013
regulation of cellular component sizeGO:0032535980.013
eye developmentGO:00016543230.013
positive regulation of ribosome biogenesisGO:009007030.013
negative regulation of protein metabolic processGO:0051248850.013
negative regulation of intrinsic apoptotic signaling pathwayGO:200124310.013
meiotic cytokinesisGO:0033206330.013
nitrogen compound transportGO:0071705850.013
negative regulation of insulin receptor signaling pathwayGO:0046627110.013
response to insulinGO:0032868290.013
positive regulation of protein catabolic processGO:0045732340.013
homeostatic processGO:00425921990.013
negative regulation of innate immune responseGO:0045824300.013
embryonic axis specificationGO:00005781070.013
gonad developmentGO:0008406500.013
Worm
cell volume homeostasisGO:000688410.013
negative regulation of molecular functionGO:0044092510.012
salivary gland histolysisGO:0035070880.012
response to fungusGO:0009620500.012
regulation of transportGO:00510491810.012
ameboidal type cell migrationGO:00016671510.012
divalent inorganic cation transportGO:0072511300.012
synaptic transmissionGO:00072682880.011
cellular catabolic processGO:00442483720.011
Human
maintenance of location in cellGO:0051651280.011
lipid metabolic processGO:00066291210.011
regulation of canonical wnt signaling pathwayGO:0060828150.011
rna localizationGO:00064031150.011
nucleoside phosphate metabolic processGO:00067531620.011
detection of stimulusGO:00516061560.011
regulation of dna metabolic processGO:0051052340.011
epithelial cell migrationGO:00106311480.011
regulation of rac protein signal transductionGO:003502030.011
cell agingGO:000756920.011
heart developmentGO:0007507820.011
neuromuscular synaptic transmissionGO:0007274670.010
translationGO:0006412690.010
regulation of protein processingGO:0070613320.010

skpA disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.012
disease of anatomical entityDOID:700.012