Drosophila melanogaster

179 known processes

cos (Dmel_CG1708)

costa

(Aliases: cos2,l(2)k16128,COS2,l(2)k16101,l(2)cos[[2]],cos-2,COS[2],l(2)161/28,Dmel\CG1708,Cos2,CG1708,Cos-2,Cos[2])

cos biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regionalizationGO:00030024160.997
segmentationGO:00352822070.992
epithelial cell developmentGO:00020642740.990
embryonic pattern specificationGO:00098801740.987
blastoderm segmentationGO:00073501590.982
border follicle cell migrationGO:00072981130.981
periodic partitioningGO:0007365290.974
epithelial cell differentiationGO:00308553220.971
segment polarity determinationGO:0007367250.964
ovarian follicle cell developmentGO:00307072480.957
post embryonic appendage morphogenesisGO:00351203850.936
ovarian follicle cell migrationGO:00072971210.908
appendage morphogenesisGO:00351073970.877
imaginal disc derived appendage morphogenesisGO:00351143950.864
imaginal disc pattern formationGO:0007447910.811
anterior posterior pattern specificationGO:00099521360.744
eye photoreceptor cell differentiationGO:00017541450.739
appendage developmentGO:00487364010.731
imaginal disc derived appendage developmentGO:00487373990.694
morphogenesis of an epitheliumGO:00020092760.665
establishment of localization in cellGO:00516494020.664
cell migrationGO:00164772380.659
columnar cuboidal epithelial cell developmentGO:00020662490.652
imaginal disc derived wing vein morphogenesisGO:0008586440.612
eye developmentGO:00016543230.579
negative regulation of response to stimulusGO:00485852580.579
columnar cuboidal epithelial cell differentiationGO:00020652560.562
compound eye photoreceptor cell differentiationGO:00017511400.556
localization of cellGO:00516742570.526
programmed cell deathGO:00125012570.510
cell motilityGO:00488702510.509
imaginal disc derived wing morphogenesisGO:00074763370.454
regulation of smoothened signaling pathwayGO:0008589280.451
axis specificationGO:00097981670.444
epithelial cell migrationGO:00106311480.434
negative regulation of cell communicationGO:00106482230.434
regulation of erbb signaling pathwayGO:1901184420.405
smoothened signaling pathwayGO:0007224490.392
cell proliferationGO:00082832990.384
negative regulation of signal transductionGO:00099682060.378
retina development in camera type eyeGO:006004140.353
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.352
sensory organ morphogenesisGO:00905962600.347
embryonic organ developmentGO:0048568500.336
negative regulation of developmental processGO:00510932010.335
negative regulation of cell differentiationGO:00455961430.331
positive regulation of transportGO:0051050920.331
positive regulation of response to stimulusGO:00485843230.323
imaginal disc derived leg morphogenesisGO:0007480800.311
stem cell differentiationGO:00488631170.309
ameboidal type cell migrationGO:00016671510.307
imaginal disc derived wing margin morphogenesisGO:0008587410.303
regulation of transportGO:00510491810.293
cellular protein modification processGO:00064644380.288
erbb signaling pathwayGO:0038127580.276
positive regulation of macromolecule metabolic processGO:00106044050.269
learning or memoryGO:00076111410.262
stem cell developmentGO:0048864790.261
central nervous system developmentGO:00074172010.260
negative regulation of wnt signaling pathwayGO:0030178280.253
leg disc morphogenesisGO:0007478800.244
signal transduction downstream of smoothenedGO:000722750.242
spinal cord patterningGO:002151110.239
photoreceptor cell differentiationGO:00465301700.237
positive regulation of gene expressionGO:00106282900.227
male gamete generationGO:00482322010.225
compound eye developmentGO:00487493070.223
leg disc developmentGO:0035218920.219
positive regulation of cellular biosynthetic processGO:00313283160.216
wing disc pattern formationGO:0035222660.211
segment specificationGO:0007379330.210
muscle structure developmentGO:00610612240.204
neuron recognitionGO:00080381010.200
negative regulation of neurogenesisGO:0050768530.194
histone modificationGO:00165701060.191
transcription from rna polymerase ii promoterGO:00063663680.186
regulation of epidermal growth factor receptor signaling pathwayGO:0042058420.184
positive regulation of signalingGO:00230562430.173
anterior posterior axis specification embryoGO:00085951030.162
positive regulation of rna biosynthetic processGO:19026802660.161
regulation of neurogenesisGO:00507671580.158
positive regulation of transcription dna templatedGO:00458932660.156
compound eye morphogenesisGO:00017452490.152
endocytosisGO:00068973100.147
regulation of transcription from rna polymerase ii promoterGO:00063573780.145
negative regulation of nitrogen compound metabolic processGO:00511722650.143
tissue migrationGO:00901301550.143
canonical wnt signaling pathwayGO:0060070210.143
secretionGO:00469031090.143
negative regulation of signalingGO:00230572190.142
positive regulation of rna metabolic processGO:00512542710.141
positive regulation of macromolecule biosynthetic processGO:00105572830.139
epidermal growth factor receptor signaling pathwayGO:0007173580.137
immune system processGO:00023763470.137
dorsal ventral pattern formationGO:00099531330.137
anterior posterior axis specificationGO:00099481090.132
regulation of neuron differentiationGO:00456641030.131
imaginal disc derived wing vein specificationGO:0007474480.130
respiratory system developmentGO:00605412130.129
axon developmentGO:00615642970.128
regulation of nucleocytoplasmic transportGO:0046822350.127
positive regulation of nucleobase containing compound metabolic processGO:00459353320.126
regulation of epithelial cell proliferationGO:005067840.123
spermatogenesisGO:00072832000.122
camera type eye developmentGO:004301040.120
positive regulation of cell differentiationGO:0045597640.108
regulation of cell differentiationGO:00455953020.108
forebrain developmentGO:003090020.104
neuron fate commitmentGO:0048663500.103
protein localization to organelleGO:0033365820.102
open tracheal system developmentGO:00074242040.101
inter male aggressive behaviorGO:0002121600.097
zygotic determination of anterior posterior axis embryoGO:0007354270.096
maintenance of location in cellGO:0051651280.096
protein modification by small protein conjugationGO:0032446790.095
brain developmentGO:00074201200.094
tissue morphogenesisGO:00487292970.094
eye morphogenesisGO:00485922600.093
enzyme linked receptor protein signaling pathwayGO:00071671790.091
molting cycleGO:0042303560.091
multicellular organism growthGO:0035264460.089
chromosome organizationGO:00512763600.089
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.088
connective tissue developmentGO:006144830.088
negative regulation of biosynthetic processGO:00098902770.087
retinal ganglion cell axon guidanceGO:0031290120.085
regulation of wnt signaling pathwayGO:0030111680.085
single organism intracellular transportGO:19025822070.085
wing disc morphogenesisGO:00074723440.084
eggshell formationGO:00307031050.083
growthGO:00400073590.083
formation of primary germ layerGO:0001704240.079
cognitionGO:00508901410.079
chromatin modificationGO:00165681470.077
negative regulation of epidermal growth factor receptor signaling pathwayGO:0042059290.077
negative regulation of nucleobase containing compound metabolic processGO:00459342610.074
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.074
protein catabolic processGO:00301631010.073
organic substance transportGO:00717022570.073
protein localizationGO:00081042840.073
mitotic cell cycle phase transitionGO:00447721380.072
positive regulation of protein localization to nucleusGO:1900182210.071
intraciliary transportGO:004207380.071
regulation of multicellular organismal developmentGO:20000264140.069
stem cell maintenanceGO:0019827670.068
gland developmentGO:00487321910.066
negative regulation of nucleic acid templated transcriptionGO:19035072400.066
mesenchymal cell differentiationGO:004876210.064
positive regulation of signal transductionGO:00099672230.063
anterior posterior pattern specification imaginal discGO:0007448160.063
regulation of cell proliferationGO:00421271630.063
negative regulation of smoothened signaling pathwayGO:0045879160.063
negative regulation of cell developmentGO:0010721620.062
olfactory learningGO:0008355560.061
regulation of immune responseGO:00507761180.061
morphogenesis of follicular epitheliumGO:0016333360.060
positive regulation of multi organism processGO:0043902400.059
epithelial tube morphogenesisGO:0060562880.057
regulation of cell developmentGO:00602842150.056
negative regulation of rna metabolic processGO:00512532510.054
germarium derived female germ line cyst encapsulationGO:003070880.054
multi organism reproductive behaviorGO:00447051210.054
wnt signaling pathwayGO:0016055980.053
imaginal disc growthGO:0007446370.053
compound eye photoreceptor fate commitmentGO:0001752360.053
limb morphogenesisGO:003510810.052
dorsal appendage formationGO:0046843470.052
single organism behaviorGO:00447083910.052
eye photoreceptor cell developmentGO:0042462810.052
carbohydrate metabolic processGO:0005975820.051
positive regulation of hh target transcription factor activityGO:000722850.051
ovarian follicle cell stalk formationGO:0030713170.051
tissue homeostasisGO:0001894360.049
proteolysisGO:00065081920.047
regulation of mitotic cell cycleGO:00073461900.047
regulation of intracellular transportGO:0032386640.046
positive regulation of cell communicationGO:00106472500.044
regulation of response to stressGO:00801342000.044
regulation of compound eye photoreceptor developmentGO:0045314120.044
embryonic axis specificationGO:00005781070.044
intracellular signal transductionGO:00355563000.044
body morphogenesisGO:001017120.044
regulation of cellular localizationGO:00603411360.044
chorion containing eggshell formationGO:00073041050.043
dorsal ventral pattern formation imaginal discGO:0007450510.043
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.043
apoptotic processGO:00069151590.043
regulation of eye photoreceptor cell developmentGO:0042478130.042
regulation of response to gamma radiationGO:200122840.042
epithelium migrationGO:00901321480.042
chromatin mediated maintenance of transcriptionGO:004809670.041
cytokinesisGO:0000910900.040
imaginal disc derived leg segmentationGO:0036011260.040
regulation of cell cycleGO:00517262910.040
homeostatic processGO:00425921990.039
catabolic processGO:00090564090.038
rna localizationGO:00064031150.038
regulation of growthGO:00400082330.038
protein modification by small protein conjugation or removalGO:00706471060.037
neuron maturationGO:0042551310.037
positive regulation of protein transportGO:0051222370.036
positive regulation of transcription factor import into nucleusGO:0042993190.036
positive regulation of cellular component organizationGO:00511301560.036
protein glycosylationGO:0006486320.036
compound eye photoreceptor developmentGO:0042051780.036
reproductive structure developmentGO:0048608740.036
secretion by cellGO:00329401010.035
positive regulation of nucleocytoplasmic transportGO:0046824240.035
negative regulation of erbb signaling pathwayGO:1901185290.035
regulation of sister chromatid cohesionGO:000706320.035
negative regulation of cellular metabolic processGO:00313243820.034
regulation of protein localization to nucleusGO:1900180290.034
cuticle pattern formationGO:0035017270.034
negative regulation of transcription factor import into nucleusGO:004299240.034
nuclear divisionGO:00002803320.034
regulation of rna splicingGO:0043484690.034
contractile actin filament bundle assemblyGO:003003810.034
negative regulation of multicellular organismal processGO:00512411420.033
nuclear transportGO:0051169720.033
spinal cord dorsal ventral patterningGO:002151310.032
photoreceptor cell developmentGO:0042461960.032
regulation of sequence specific dna binding transcription factor activityGO:0051090120.032
developmental pigmentationGO:0048066680.032
cellular macromolecule localizationGO:00707272200.032
eggshell chorion assemblyGO:0007306660.031
germarium derived egg chamber formationGO:00072931010.031
intracellular transportGO:00469072280.031
glycoprotein metabolic processGO:0009100410.031
positive regulation of protein import into nucleusGO:0042307210.031
regulation of protein stabilityGO:0031647430.030
covalent chromatin modificationGO:00165691060.030
peptidyl threonine phosphorylationGO:001810720.030
positive regulation of developmental growthGO:0048639620.030
synaptic target recognitionGO:0008039450.030
positive regulation of nucleic acid templated transcriptionGO:19035082660.030
germ line cyst encapsulationGO:004813880.029
myoblast migrationGO:005145120.029
chromatin organizationGO:00063252070.029
dorsal ventral axis specification ovarian follicular epitheliumGO:0008069130.029
protein alkylationGO:0008213430.029
sex differentiationGO:0007548810.029
negative regulation of cellular protein metabolic processGO:0032269850.029
lateral inhibitionGO:00463312060.029
memoryGO:0007613940.028
regulation of protein transportGO:0051223570.028
regulation of apoptotic processGO:00429811300.028
meiosis iGO:0007127590.028
anatomical structure homeostasisGO:0060249970.028
regulation of imaginal disc growthGO:0045570260.028
tripartite regional subdivisionGO:00073511030.028
cell cycle phase transitionGO:00447701400.028
positive regulation of developmental processGO:00510941430.027
negative regulation of nervous system developmentGO:0051961920.027
response to abiotic stimulusGO:00096283410.026
head developmentGO:00603221350.026
hindgut developmentGO:0061525580.026
single organism carbohydrate metabolic processGO:0044723720.026
embryo development ending in birth or egg hatchingGO:00097921520.026
reproductive behaviorGO:00190981220.025
negative regulation of cell proliferationGO:0008285690.025
neurological system processGO:00508773580.024
cellular amino acid metabolic processGO:0006520610.024
muscle system processGO:0003012210.024
negative regulation of transcription dna templatedGO:00458922370.024
organelle assemblyGO:00709251980.023
regulation of rho gtpase activityGO:0032319200.023
regulation of canonical wnt signaling pathwayGO:0060828150.023
renal system developmentGO:0072001720.023
multicellular organismal reproductive behaviorGO:00330571100.023
response to organic cyclic compoundGO:0014070890.022
organic acid metabolic processGO:00060821030.022
nuclear importGO:0051170510.022
spindle organizationGO:00070512530.022
glycoprotein biosynthetic processGO:0009101410.022
olfactory behaviorGO:0042048970.022
liposaccharide metabolic processGO:190350980.022
positive regulation of protein metabolic processGO:00512471280.022
larval developmentGO:00021641040.022
mesoderm developmentGO:0007498780.022
smoothened signaling pathway involved in ventral spinal cord patterningGO:002191000.022
cellular response to abiotic stimulusGO:0071214580.022
retina morphogenesis in camera type eyeGO:006004220.021
dna metabolic processGO:00062592270.021
single organism cellular localizationGO:19025801800.021
cellular amine metabolic processGO:0044106120.021
spermatid differentiationGO:00485151140.021
immune system developmentGO:0002520570.021
foregut morphogenesisGO:0007440100.020
nucleocytoplasmic transportGO:0006913720.020
negative regulation of epithelial cell proliferationGO:005068040.020
protein modification processGO:00362114380.020
carbohydrate derivative metabolic processGO:19011352170.020
multi organism behaviorGO:00517051750.020
hemopoiesisGO:0030097460.020
cellular response to chemical stimulusGO:00708871990.020
cell fate specificationGO:0001708710.020
amine metabolic processGO:0009308120.020
kidney developmentGO:000182230.020
regulation of protein metabolic processGO:00512462560.019
pupal developmentGO:0035209110.019
cellular response to ionizing radiationGO:0071479150.019
chaeta developmentGO:0022416970.019
receptor clusteringGO:004311330.019
positive regulation of sequence specific dna binding transcription factor activityGO:005109190.019
hematopoietic or lymphoid organ developmentGO:0048534570.019
torso signaling pathwayGO:0008293210.018
phagocytosisGO:00069092150.018
protein methylationGO:0006479430.018
developmental maturationGO:00217001720.018
tube developmentGO:00352952440.018
proteasomal protein catabolic processGO:0010498590.018
locomotor rhythmGO:0045475560.018
endomembrane system organizationGO:00102561190.018
positive regulation of biosynthetic processGO:00098913160.018
chemosensory behaviorGO:00076351060.018
protein ubiquitinationGO:0016567700.018
regulation of cytoplasmic transportGO:1903649470.017
cellular response to radiationGO:0071478520.017
female germ line cyst encapsulationGO:004813980.017
regulation of programmed cell deathGO:00430671520.017
camera type eye morphogenesisGO:004859320.017
ovipositionGO:0018991190.017
eye photoreceptor cell fate commitmentGO:0042706370.017
neuron projection guidanceGO:00974852410.017
negative regulation of macromolecule biosynthetic processGO:00105582700.017
regulation of localizationGO:00328792750.017
negative regulation of sequence specific dna binding transcription factor activityGO:004343340.017
regulation of intracellular protein transportGO:0033157460.017
multi multicellular organism processGO:00447061230.017
methylationGO:0032259470.017
multicellular organismal agingGO:00102591400.016
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161540.016
wing disc dorsal ventral pattern formationGO:0048190470.016
maintenance of gastrointestinal epitheliumGO:003027730.016
telencephalon developmentGO:002153720.016
peptidyl amino acid modificationGO:00181931050.016
protein import into nucleusGO:0006606510.016
histone methylationGO:0016571400.016
cytoplasmic transportGO:00164821300.016
macromolecule catabolic processGO:00090571610.015
positive regulation of nf kappab import into nucleusGO:004234610.015
morphogenesis of a branching epitheliumGO:0061138450.015
oocyte microtubule cytoskeleton organizationGO:0016325350.015
positive regulation of wnt signaling pathwayGO:0030177250.015
response to oxygen containing compoundGO:19017002000.015
cellular macromolecule catabolic processGO:00442651360.015
regulation of mitosisGO:0007088560.015
cellular protein catabolic processGO:0044257830.015
negative regulation of notch signaling pathwayGO:0045746410.015
positive regulation of intracellular transportGO:0032388420.015
spermatid developmentGO:0007286980.015
imaginal disc derived leg joint morphogenesisGO:0016348150.015
response to ionizing radiationGO:0010212320.014
chromosome segregationGO:00070591570.014
purine nucleoside monophosphate metabolic processGO:0009126500.014
cell fate determinationGO:0001709910.014
establishment of protein localizationGO:00451841630.014
negative regulation of rna biosynthetic processGO:19026792400.014
regulation of stem cell proliferationGO:0072091400.014
stress activated mapk cascadeGO:0051403520.014
histone h3 k4 methylationGO:0051568160.013
regulation of chromatin organizationGO:1902275320.013
regulation of pathway restricted smad protein phosphorylationGO:006039310.013
negative regulation of gene expressionGO:00106293870.013
reproductive system developmentGO:0061458740.013
regulation of nervous system developmentGO:00519602480.013
positive regulation of canonical wnt signaling pathwayGO:009026370.013
modification dependent protein catabolic processGO:0019941780.013
regulation of protein import into nucleusGO:0042306280.013
cell deathGO:00082192790.013
regulation of epidermal growth factor activated receptor activityGO:000717640.013
response to woundingGO:0009611940.013
positive regulation of intracellular protein transportGO:0090316300.012
response to radiationGO:00093141550.012
mushroom body developmentGO:0016319700.012
regulation of cell deathGO:00109411730.012
endoderm formationGO:000170630.012
neuroblast fate commitmentGO:0014017190.012
positive regulation of nitrogen compound metabolic processGO:00511733540.012
protein processingGO:0016485680.012
regulation of secretionGO:0051046440.012
positive regulation of neurogenesisGO:0050769410.011
induction of programmed cell death by ecdysoneGO:0035078120.011
regulation of establishment of planar polarityGO:0090175220.011
positive regulation of molecular functionGO:00440931360.011
positive regulation of reproductive processGO:200024370.011
small molecule metabolic processGO:00442813050.011
regulation of organ growthGO:0046620420.011
embryonic morphogenesisGO:00485982060.011
regulation of protein export from nucleusGO:004682530.011
posttranscriptional regulation of gene expressionGO:00106081450.011
torc1 signalingGO:0038202120.011
ubiquitin dependent protein catabolic processGO:0006511780.011
sulfur compound metabolic processGO:0006790590.011
regulation of protein modification by small protein conjugation or removalGO:1903320250.011
regulation of cellular component biogenesisGO:00440872010.011
regulation of cell junction assemblyGO:190188820.011
negative regulation of intracellular signal transductionGO:1902532570.010
meiotic chromosome segregationGO:0045132590.010
regulation of cell substrate adhesionGO:001081020.010
immune responseGO:00069552460.010
cellular protein complex assemblyGO:0043623710.010
decapentaplegic signaling pathwayGO:0008101190.010
carboxylic acid metabolic processGO:0019752920.010
phosphorylationGO:00163102940.010
proteolysis involved in cellular protein catabolic processGO:0051603830.010
eye antennal disc developmentGO:0035214600.010
pole plasm assemblyGO:0007315610.010

cos disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
organ system cancerDOID:005068600.092
cancerDOID:16200.092
disease of cellular proliferationDOID:1456600.092