Drosophila melanogaster

199 known processes

cnc (Dmel_CG17894)

cap-n-collar

(Aliases: CG4566,Dmel\CG17894,CG17894,anon-WO0153538.6,anon-WO0153538.7,CG4578,l(3)03921,CNC,l(3)j5E7,CNC_DROME,5134,Cnc)

cnc biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
dendrite developmentGO:00163582040.995
positive regulation of gene expressionGO:00106282900.995
positive regulation of transcription dna templatedGO:00458932660.986
transcription from rna polymerase ii promoterGO:00063663680.970
regulation of transcription from rna polymerase ii promoterGO:00063573780.969
negative regulation of transcription dna templatedGO:00458922370.966
Human Mouse
positive regulation of rna metabolic processGO:00512542710.943
dendrite morphogenesisGO:00488131990.941
positive regulation of nitrogen compound metabolic processGO:00511733540.935
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.930
Human Mouse
positive regulation of macromolecule metabolic processGO:00106044050.929
positive regulation of nucleic acid templated transcriptionGO:19035082660.927
regionalizationGO:00030024160.914
negative regulation of nucleobase containing compound metabolic processGO:00459342610.899
Human Mouse
developmental maturationGO:00217001720.879
positive regulation of macromolecule biosynthetic processGO:00105572830.825
axis specificationGO:00097981670.782
negative regulation of cellular biosynthetic processGO:00313272770.779
Human Mouse
anterior posterior pattern specificationGO:00099521360.768
blastoderm segmentationGO:00073501590.768
positive regulation of rna biosynthetic processGO:19026802660.758
stem cell differentiationGO:00488631170.744
negative regulation of developmental processGO:00510932010.650
Mouse
oocyte differentiationGO:00099941450.622
negative regulation of macromolecule biosynthetic processGO:00105582700.591
Human Mouse
positive regulation of developmental processGO:00510941430.569
positive regulation of biosynthetic processGO:00098913160.554
growthGO:00400073590.548
positive regulation of cellular biosynthetic processGO:00313283160.547
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.542
stem cell developmentGO:0048864790.523
developmental programmed cell deathGO:00106231380.523
programmed cell deathGO:00125012570.492
Human
cell maturationGO:00484691440.486
negative regulation of nucleic acid templated transcriptionGO:19035072400.482
Human Mouse
tissue morphogenesisGO:00487292970.475
oocyte developmentGO:00485991240.472
regulation of dendrite morphogenesisGO:0048814280.458
gland developmentGO:00487321910.457
negative regulation of biosynthetic processGO:00098902770.456
Human Mouse
regulation of cell differentiationGO:00455953020.450
positive regulation of nucleobase containing compound metabolic processGO:00459353320.434
segmentationGO:00352822070.433
morphogenesis of an epitheliumGO:00020092760.422
negative regulation of rna metabolic processGO:00512532510.410
Human Mouse
anterior posterior axis specification embryoGO:00085951030.387
tube morphogenesisGO:00352391910.384
exocrine system developmentGO:00352721620.371
embryonic morphogenesisGO:00485982060.367
embryonic axis specificationGO:00005781070.364
gastrulationGO:0007369700.356
localization of cellGO:00516742570.347
negative regulation of cell differentiationGO:00455961430.345
head developmentGO:00603221350.341
cell deathGO:00082192790.338
Human Rat
regulation of anatomical structure sizeGO:00900661630.324
small molecule metabolic processGO:00442813050.311
torso signaling pathwayGO:0008293210.295
regulation of localizationGO:00328792750.270
cell motilityGO:00488702510.258
cell cycle checkpointGO:0000075950.253
regulation of anatomical structure morphogenesisGO:00226032420.252
Mouse
cell fate determinationGO:0001709910.240
tripartite regional subdivisionGO:00073511030.240
deathGO:00162652840.240
Human Rat
positive regulation of neurogenesisGO:0050769410.234
cellular response to chemical stimulusGO:00708871990.232
Human Mouse Rat
terminal region determinationGO:0007362250.214
tissue deathGO:00162711020.205
salivary gland developmentGO:00074311620.203
regulation of growthGO:00400082330.202
regulation of cell developmentGO:00602842150.192
regulation of nervous system developmentGO:00519602480.191
agingGO:00075681430.188
regulation of cell deathGO:00109411730.180
Human Rat
mesoderm developmentGO:0007498780.180
actin filament based processGO:00300292200.180
regulation of apoptotic processGO:00429811300.179
Human
digestive tract morphogenesisGO:00485461270.174
histolysisGO:00075591020.172
salivary gland cell autophagic cell deathGO:0035071830.166
organonitrogen compound metabolic processGO:19015643180.164
dendrite guidanceGO:0070983210.162
response to external biotic stimulusGO:00432072930.153
endocytosisGO:00068973100.153
homeostatic processGO:00425921990.152
Mouse
mesenchymal cell differentiationGO:004876210.142
muscle structure developmentGO:00610612240.141
response to ecdysoneGO:0035075340.138
anterior posterior axis specificationGO:00099481090.137
positive regulation of cell differentiationGO:0045597640.136
organonitrogen compound biosynthetic processGO:19015661170.135
negative regulation of cell developmentGO:0010721620.133
phosphorylationGO:00163102940.131
regulation of phosphorylationGO:00423251470.131
negative regulation of gene expressionGO:00106293870.130
Human Mouse
establishment of localization in cellGO:00516494020.129
regulation of phosphate metabolic processGO:00192202100.128
negative regulation of nitrogen compound metabolic processGO:00511722650.127
Human Mouse
response to organic substanceGO:00100332840.125
Human Mouse
enzyme linked receptor protein signaling pathwayGO:00071671790.122
embryonic pattern specificationGO:00098801740.116
tube developmentGO:00352952440.113
oocyte anterior posterior axis specificationGO:0007314720.111
negative regulation of rna biosynthetic processGO:19026792400.110
Human Mouse
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.110
Human Mouse
response to alcoholGO:0097305950.104
regulation of cell morphogenesis involved in differentiationGO:0010769610.102
negative regulation of multicellular organismal processGO:00512411420.102
Mouse
pole plasm mrna localizationGO:0019094490.102
salivary gland morphogenesisGO:00074351450.101
response to oxidative stressGO:0006979860.101
intracellular mrna localizationGO:0008298660.096
response to other organismGO:00517072930.096
cell migrationGO:00164772380.094
regulation of circadian rhythmGO:0042752490.093
response to abiotic stimulusGO:00096283410.092
Human
segment specificationGO:0007379330.091
regulation of cell migrationGO:0030334220.091
kidney developmentGO:000182230.086
gland morphogenesisGO:00226121450.085
regulation of actin filament lengthGO:0030832270.083
body morphogenesisGO:001017120.082
regulation of cell cycleGO:00517262910.080
ectodermal placode developmentGO:007169640.080
negative regulation of cellular component organizationGO:00511291080.078
Mouse
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.078
negative regulation of cell deathGO:0060548810.077
Human Rat
response to oxygen containing compoundGO:19017002000.077
Human Mouse
positive regulation of cellular protein metabolic processGO:00322701180.075
Mouse
regulation of neuron projection developmentGO:0010975690.074
positive regulation of cell deathGO:0010942690.074
embryonic development via the syncytial blastodermGO:00017001480.072
regulation of programmed cell deathGO:00430671520.072
Human
cellular response to nutrient levelsGO:0031669620.071
positive regulation of cellular amino acid metabolic processGO:004576400.071
neuron fate commitmentGO:0048663500.070
regulation of cellular component movementGO:0051270420.069
actin polymerization or depolymerizationGO:0008154310.069
circulatory system processGO:0003013370.069
intracellular steroid hormone receptor signaling pathwayGO:0030518120.068
regulation of dendrite developmentGO:0050773370.067
axon regenerationGO:003110380.066
regulation of translationGO:0006417560.066
autophagic cell deathGO:0048102830.066
cellular response to oxygen containing compoundGO:1901701790.064
Human Mouse
actin filament polymerizationGO:0030041270.064
negative regulation of response to stimulusGO:00485852580.064
Human
regulation of multicellular organismal developmentGO:20000264140.063
adenylate cyclase modulating g protein coupled receptor signaling pathwayGO:0007188170.063
male gamete generationGO:00482322010.063
embryonic epithelial tube formationGO:000183860.061
spermatogenesisGO:00072832000.060
response to starvationGO:0042594970.059
rna localizationGO:00064031150.058
respiratory system developmentGO:00605412130.058
positive regulation of response to stimulusGO:00485843230.058
Mouse
cell proliferationGO:00082832990.057
neuroblast differentiationGO:0014016290.057
regulation of phosphorus metabolic processGO:00511742100.057
regulation of cellular component sizeGO:0032535980.057
response to lipidGO:0033993380.056
salivary gland histolysisGO:0035070880.055
regulation of steroid metabolic processGO:001921820.054
regulation of neurogenesisGO:00507671580.054
neuron recognitionGO:00080381010.053
actin filament organizationGO:00070151260.053
forebrain developmentGO:003090020.053
establishment of organelle localizationGO:00516561220.052
posterior head segmentationGO:003528960.052
positive regulation of immune responseGO:0050778630.052
single organism biosynthetic processGO:00447112060.052
organic substance transportGO:00717022570.050
brain developmentGO:00074201200.049
reproductive system developmentGO:0061458740.049
Mouse
response to bacteriumGO:00096171980.049
regulation of neuron differentiationGO:00456641030.049
atp metabolic processGO:0046034490.049
negative regulation of apoptotic processGO:0043066630.049
Human
developmental cell growthGO:0048588520.048
development of primary sexual characteristicsGO:0045137500.048
zygotic determination of anterior posterior axis embryoGO:0007354270.048
developmental growthGO:00485892800.048
regulation of organ morphogenesisGO:2000027780.048
reproductive structure developmentGO:0048608740.047
Mouse
digestive system developmentGO:00551231490.047
mesenchyme developmentGO:006048590.047
cellular homeostasisGO:0019725800.047
positive regulation of signalingGO:00230562430.047
outflow tract morphogenesisGO:000315140.047
chaeta developmentGO:0022416970.046
regulation of actin filament polymerizationGO:0030833250.045
response to endogenous stimulusGO:00097191190.045
morphogenesis of embryonic epitheliumGO:0016331940.045
meiosis iGO:0007127590.045
mesenchymal cell developmentGO:001403110.045
regulation of cellular ketone metabolic processGO:001056530.043
peptidyl tyrosine phosphorylationGO:0018108240.043
regulation of cell cycle phase transitionGO:19019871300.042
cell recognitionGO:00080371020.042
camera type eye developmentGO:004301040.042
regulation of cellular protein metabolic processGO:00322682430.040
Mouse
intracellular mrna localization involved in pattern specification processGO:0060810560.039
regulation of epithelial cell differentiationGO:003085640.039
feeding behaviorGO:0007631500.039
response to biotic stimulusGO:00096072940.039
protein heterooligomerizationGO:005129140.039
regulation of neural precursor cell proliferationGO:2000177350.038
regulation of developmental growthGO:00486381740.038
positive regulation of cell communicationGO:00106472500.038
head segmentationGO:0035287130.038
dorsal ventral axis specification ovarian follicular epitheliumGO:0008069130.038
single organism catabolic processGO:00447122280.037
specification of segmental identity headGO:0007380110.037
sex differentiationGO:0007548810.037
negative regulation of cell proliferationGO:0008285690.037
negative regulation of cell communicationGO:00106482230.037
Human
positive regulation of neuron differentiationGO:0045666260.037
protein modification processGO:00362114380.037
Human Mouse
negative regulation of signal transductionGO:00099682060.037
Human
production of molecular mediator of immune responseGO:0002440460.036
inositol lipid mediated signalingGO:004801740.036
protein polymerizationGO:0051258420.036
protein transportGO:00150311550.036
phosphatidylinositol mediated signalingGO:004801540.035
mesodermal cell differentiationGO:004833370.035
positive regulation of multicellular organismal processGO:00512401430.035
Mouse
multicellular organismal agingGO:00102591400.034
positive regulation of cell proliferationGO:0008284470.034
blood circulationGO:0008015260.034
larval developmentGO:00021641040.034
pole plasm rna localizationGO:0007316520.034
neuroblast developmentGO:0014019130.033
chemotaxisGO:00069352490.033
cellular ketone metabolic processGO:0042180240.033
morphogenesis of follicular epitheliumGO:0016333360.033
positive regulation of protein metabolic processGO:00512471280.033
Mouse
rhythmic processGO:00485111060.032
wing disc morphogenesisGO:00074723440.032
maternal determination of anterior posterior axis embryoGO:0008358740.032
eye developmentGO:00016543230.031
regulation of protein polymerizationGO:0032271280.031
embryonic hemopoiesisGO:0035162260.031
regulation of cell proliferationGO:00421271630.031
synaptic target recognitionGO:0008039450.031
epithelial tube formationGO:007217570.031
negative regulation of neurogenesisGO:0050768530.030
muscle organ developmentGO:00075171270.030
jak stat cascadeGO:0007259490.030
positive regulation of programmed cell deathGO:0043068620.030
positive regulation of phosphorus metabolic processGO:00105621390.029
regulation of oocyte developmentGO:0060281270.029
positive regulation of peptidyl tyrosine phosphorylationGO:005073140.029
cellular catabolic processGO:00442483720.029
Human
ribonucleoside metabolic processGO:00091191270.028
response to inorganic substanceGO:0010035440.028
Human Mouse
actin cytoskeleton organizationGO:00300362060.028
regulation of locomotionGO:0040012420.028
ribonucleotide biosynthetic processGO:0009260280.028
epithelial cell differentiationGO:00308553220.028
phosphatidylinositol 3 kinase signalingGO:001406540.027
organic cyclic compound catabolic processGO:19013611680.027
carbohydrate derivative metabolic processGO:19011352170.027
negative regulation of cell cycleGO:00457861160.027
polyol biosynthetic processGO:004617330.027
positive regulation of apoptotic processGO:0043065470.027
motor neuron axon guidanceGO:0008045580.027
rhythmic behaviorGO:0007622760.026
negative regulation of cellular metabolic processGO:00313243820.026
Human Mouse
chemical homeostasisGO:0048878920.026
regulation of organelle organizationGO:00330431960.026
positive regulation of intracellular signal transductionGO:19025331160.025
autophagyGO:00069141080.025
notch signaling pathwayGO:00072191200.025
histone lysine methylationGO:0034968320.025
r7 cell fate commitmentGO:0007465120.025
cell growthGO:00160491080.025
determination of adult lifespanGO:00083401370.025
ameboidal type cell migrationGO:00016671510.025
skeletal muscle organ developmentGO:0060538480.025
translationGO:0006412690.024
circadian rhythmGO:00076231050.024
secretionGO:00469031090.024
regulation of multicellular organism growthGO:0040014400.024
negative regulation of nervous system developmentGO:0051961920.024
protein dna complex subunit organizationGO:0071824860.024
negative regulation of programmed cell deathGO:0043069720.023
Human
immune responseGO:00069552460.023
cell cycle dna replicationGO:0044786230.023
response to temperature stimulusGO:00092661060.023
response to woundingGO:0009611940.023
Mouse
response to axon injuryGO:0048678120.023
synapse organizationGO:00508081960.023
induction of programmed cell death by ecdysoneGO:0035078120.023
response to ethanolGO:0045471590.022
establishment of nucleus localizationGO:0040023260.022
positive regulation of cell developmentGO:0010720610.022
telencephalon developmentGO:002153720.022
wound healingGO:0042060750.022
Mouse
regulation of cell cycle processGO:00105641810.022
regulation of hydrolase activityGO:0051336970.022
cytoplasm organizationGO:0007028640.021
regulation of intracellular signal transductionGO:19025312360.021
Human
kidney morphogenesisGO:006099330.021
axonogenesisGO:00074092900.021
maintenance of locationGO:0051235730.021
nucleobase containing compound catabolic processGO:00346551650.021
oocyte axis specificationGO:00073091080.021
negative regulation of sequence specific dna binding transcription factor activityGO:004343340.021
regulation of response to stressGO:00801342000.021
Human Mouse
appendage morphogenesisGO:00351073970.021
cardiac cell fate determinationGO:006091330.021
positive regulation of endopeptidase activityGO:0010950260.021
dorsal ventral pattern formationGO:00099531330.020
retina development in camera type eyeGO:006004140.020
intracellular receptor signaling pathwayGO:0030522190.019
cellular response to growth factor stimulusGO:0071363300.019
positive regulation of phosphate metabolic processGO:00459371390.019
nephron tubule morphogenesisGO:007207830.019
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280230.019
cell cell signaling involved in cell fate commitmentGO:00451682100.019
vesicle mediated transportGO:00161923810.019
epithelial tube morphogenesisGO:0060562880.019
small gtpase mediated signal transductionGO:0007264880.019
regulation of ras protein signal transductionGO:0046578930.019
response to growth factorGO:0070848310.019
regulation of cell projection organizationGO:0031344920.019
meiotic nuclear divisionGO:00071261510.019
regulation of transportGO:00510491810.019
positive regulation of axonogenesisGO:005077220.019
positive regulation of catabolic processGO:00098961050.018
cell adhesionGO:00071551360.018
positive regulation of organelle organizationGO:0010638650.018
positive regulation of cellular catabolic processGO:0031331950.018
tube formationGO:0035148210.018
amide biosynthetic processGO:0043604420.018
regulation of malpighian tubule diameterGO:003529730.017
regulation of phosphatase activityGO:001092130.017
positive regulation of phosphorylationGO:0042327870.017
chromosome organizationGO:00512763600.017
regulation of reproductive processGO:2000241540.017
immune system developmentGO:0002520570.017
Mouse
cellular ion homeostasisGO:0006873390.017
regulation of cellular component biogenesisGO:00440872010.016
positive regulation of signal transductionGO:00099672230.016
vitamin biosynthetic processGO:000911010.016
secretion by cellGO:00329401010.016
ribonucleotide metabolic processGO:00092591450.016
mitotic spindle organizationGO:00070522200.016
dna metabolic processGO:00062592270.016
transition metal ion homeostasisGO:0055076170.016
axonal fasciculationGO:0007413120.016
striated muscle cell differentiationGO:0051146900.016
regenerationGO:0031099160.016
regulation of protein modification processGO:00313991120.016
Mouse
response to lipopolysaccharideGO:003249640.016
oocyte maturationGO:000155630.016
ribonucleoside monophosphate catabolic processGO:0009158390.016
cellular amino acid metabolic processGO:0006520610.016
cellular protein modification processGO:00064644380.016
Human Mouse
sensory organ morphogenesisGO:00905962600.016
regulation of epidermal cell differentiationGO:004560430.016
cellular chemical homeostasisGO:0055082400.015
cellular protein complex assemblyGO:0043623710.015
immune response activating signal transductionGO:000275720.015
gliogenesisGO:0042063800.015
rho protein signal transductionGO:0007266140.015
regulation of molecular functionGO:00650092170.015
ecdysone mediated induction of salivary gland cell autophagic cell deathGO:0035072120.015
post embryonic appendage morphogenesisGO:00351203850.015
signal transduction in response to dna damageGO:004277030.015
response to extracellular stimulusGO:00099911160.015
biological adhesionGO:00226101380.015
macromolecular complex assemblyGO:00650032560.015
establishment of protein localizationGO:00451841630.015
heart contractionGO:0060047260.014
purine ribonucleoside monophosphate metabolic processGO:0009167500.014
positive regulation of cell migrationGO:003033520.014
organophosphate metabolic processGO:00196371950.014
positive regulation of growthGO:0045927750.014
locomotory behaviorGO:00076261760.014
response to monosaccharideGO:003428440.014
cellular amine metabolic processGO:0044106120.014
positive regulation of neuron apoptotic processGO:004352510.014
karyosome formationGO:0030717220.014
columnar cuboidal epithelial cell developmentGO:00020662490.014
cell divisionGO:00513012480.014
positive regulation of developmental growthGO:0048639620.014
lipid metabolic processGO:00066291210.014
negative regulation of intrinsic apoptotic signaling pathwayGO:200124310.014
Human
oocyte nucleus localization involved in oocyte dorsal ventral axis specificationGO:0051663120.014
positive regulation of molecular functionGO:00440931360.014
regulation of synapse structure and activityGO:00508031280.014
positive regulation of nervous system developmentGO:0051962690.014
rna processingGO:00063961470.014
positive regulation of antimicrobial peptide biosynthetic processGO:0002807260.014
carbohydrate derivative biosynthetic processGO:1901137850.014
mapk cascadeGO:00001651070.014
ras protein signal transductionGO:0007265880.014
regulation of cellular localizationGO:00603411360.013
regulation of defense responseGO:00313471020.013
regulation of multi organism processGO:00439001310.013
regulation of cellular amine metabolic processGO:003323830.013
germarium derived oocyte fate determinationGO:0007294260.013
cyclic purine nucleotide metabolic processGO:0052652250.013
gonad developmentGO:0008406500.013
camera type eye morphogenesisGO:004859320.013
female germ line cyst encapsulationGO:004813980.013
stem cell proliferationGO:0072089880.013
intercellular bridge organizationGO:0043063140.013
cellular response to extracellular stimulusGO:0031668640.013
single organism intracellular transportGO:19025822070.013
nucleoside phosphate catabolic processGO:19012921100.013
defense response to other organismGO:00985422250.013
neuroblast fate commitmentGO:0014017190.013
macroautophagyGO:0016236420.013
axon guidanceGO:00074112330.013
g protein coupled receptor signaling pathwayGO:00071861360.012
nephron developmentGO:007200630.012
negative regulation of multi organism processGO:0043901290.012
innate immune responseGO:00450871440.012
response to copper ionGO:004668840.012
hematopoietic progenitor cell differentiationGO:000224410.012
regulation of notch signaling pathwayGO:00085931000.012
negative regulation of notch signaling pathwayGO:0045746410.012
nucleoside phosphate metabolic processGO:00067531620.012
nucleoside monophosphate metabolic processGO:0009123520.012
alcohol metabolic processGO:0006066250.012
connective tissue developmentGO:006144830.012
ovarian follicle cell developmentGO:00307072480.012
regulation of actin polymerization or depolymerizationGO:0008064270.012
axon developmentGO:00615642970.012
response to metal ionGO:0010038230.012
positive regulation of cysteine type endopeptidase activityGO:2001056240.012
spermatid differentiationGO:00485151140.011
amine metabolic processGO:0009308120.011
cellular response to organic substanceGO:00713101320.011
Human Mouse
antimicrobial humoral responseGO:0019730990.011
cellular nitrogen compound catabolic processGO:00442701650.011
cellular response to starvationGO:0009267610.011
protein processingGO:0016485680.011
cellular metal ion homeostasisGO:0006875310.011
dna templated transcription initiationGO:0006352250.011
response to sterolGO:0036314340.011
positive regulation of cellular amine metabolic processGO:003324000.011
sphingolipid metabolic processGO:0006665190.011
regulation of immune responseGO:00507761180.011
endomembrane system organizationGO:00102561190.011
aromatic compound catabolic processGO:00194391660.011
hematopoietic or lymphoid organ developmentGO:0048534570.011
Mouse
apoptotic processGO:00069151590.011
Human
germ cell migrationGO:0008354430.011
positive regulation of catalytic activityGO:00430851180.011
dna conformation changeGO:00711031050.011
positive regulation of actin filament polymerizationGO:0030838110.011
molting cycle chitin based cuticleGO:0007591560.010
viral life cycleGO:001905870.010
carbohydrate metabolic processGO:0005975820.010
regulation of hormone levelsGO:0010817400.010
cellular macromolecule catabolic processGO:00442651360.010
Human
positive regulation of defense responseGO:0031349590.010
actomyosin structure organizationGO:0031032560.010
positive regulation of translationGO:0045727120.010
ribonucleoside triphosphate metabolic processGO:00091991190.010
oxoacid metabolic processGO:00434361030.010

cnc disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.525
musculoskeletal system diseaseDOID:1700.095
organ system cancerDOID:005068600.051
cancerDOID:16200.051
disease of cellular proliferationDOID:1456600.051
cardiovascular system diseaseDOID:128700.029
bone diseaseDOID:008000100.021
connective tissue diseaseDOID:6500.021
urinary system diseaseDOID:1800.012
congenital nervous system abnormalityDOID:249000.012
physical disorderDOID:008001500.012
immune system diseaseDOID:291400.011