IMP: Integrative Multi-species Prediction

Drosophila melanogaster

168 known processes

shot (Dmel_CG18076)

short stop

(Aliases: Grv,grv,l(2)k15606,Shot,l(2)k04204,l(2)CA4,kak,l(2)k05821,Dmel\CG18076,CG18637,shortstop/kakapo,CG18076,l(2)k05434,kop,l(2)k03010,l(2)k10821,42/4)

FLYBASE: FBgn0013733
Entrez: 36542
UniProtKB: B7YZG6
UniProtKB: B7YZG5
UniProtKB: B7YZG4
UniProtKB: B7YZG3
UniProtKB: B7YZG2
UniProtKB: A1Z9J1
UniProtKB: A1Z9J0
UniProtKB: A1Z9J3
UniProtKB: A1Z9J2
UniProtKB: E1JH64
UniProtKB: E1JH65
UniProtKB: E1JH62
UniProtKB: E1JH63
UniProtKB: A1Z9I8
UniProtKB: A1Z9I9

Process Predictions
Disease Predictions

shot biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
axon guidance	GO:0007411	233	1.000
axonogenesis	GO:0007409	290	1.000
neuron projection guidance	GO:0097485	241	1.000
chemotaxis	GO:0006935	249	1.000
axon development	GO:0061564	297	1.000
motor neuron axon guidance	GO:0008045	58	0.999
regulation of nervous system development	GO:0051960	248	0.996
muscle structure development	GO:0061061	224	0.989
cellular protein modification process	GO:0006464	438	0.975
taxis	GO:0042330	304	0.954
establishment of localization in cell	GO:0051649	402	0.948	Human Mouse
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.942
synapse assembly	GO:0007416	143	0.939
regulation of multicellular organismal development	GO:2000026	414	0.937
positive regulation of nervous system development	GO:0051962	69	0.927
developmental growth	GO:0048589	280	0.918
post embryonic appendage morphogenesis	GO:0035120	385	0.913
growth	GO:0040007	359	0.913
synapse organization	GO:0050808	196	0.911
cell maturation	GO:0048469	144	0.901
regulation of tube architecture open tracheal system	GO:0035152	68	0.891
regulation of growth	GO:0040008	233	0.889
immune system process	GO:0002376	347	0.870
regulation of localization	GO:0032879	275	0.866	Mouse
striated muscle cell differentiation	GO:0051146	90	0.864
actin cytoskeleton organization	GO:0030036	206	0.864
dendrite morphogenesis	GO:0048813	199	0.856
epithelial cell differentiation	GO:0030855	322	0.844
circulatory system development	GO:0072359	82	0.842
cellular protein complex assembly	GO:0043623	71	0.835
regulation of protein metabolic process	GO:0051246	256	0.821
protein localization	GO:0008104	284	0.809	Human Mouse
forebrain development	GO:0030900	2	0.807
developmental maturation	GO:0021700	172	0.802
positive regulation of macromolecule metabolic process	GO:0010604	405	0.800
endomembrane system organization	GO:0010256	119	0.791	Human
protein complex assembly	GO:0006461	200	0.790
cellular macromolecular complex assembly	GO:0034622	153	0.789
imaginal disc derived wing morphogenesis	GO:0007476	337	0.789
morphogenesis of an epithelium	GO:0002009	276	0.784
regulation of neurogenesis	GO:0050767	158	0.783
death	GO:0016265	284	0.779
muscle organ development	GO:0007517	127	0.767
regulation of cellular localization	GO:0060341	136	0.764
embryonic morphogenesis	GO:0048598	206	0.757	Mouse
oocyte differentiation	GO:0009994	145	0.738
appendage development	GO:0048736	401	0.738
synaptic growth at neuromuscular junction	GO:0051124	119	0.725
macromolecular complex assembly	GO:0065003	256	0.722
open tracheal system development	GO:0007424	204	0.720
regulation of synapse organization	GO:0050807	110	0.717
tissue morphogenesis	GO:0048729	297	0.714
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.707
positive regulation of gene expression	GO:0010628	290	0.707
learning	GO:0007612	75	0.694
phosphorylation	GO:0016310	294	0.692
positive regulation of transport	GO:0051050	92	0.692
multi multicellular organism process	GO:0044706	123	0.687
protein complex biogenesis	GO:0070271	201	0.682
muscle cell differentiation	GO:0042692	103	0.667
regulation of synapse structure and activity	GO:0050803	128	0.648
regulation of cell cycle	GO:0051726	291	0.638
positive regulation of cellular protein metabolic process	GO:0032270	118	0.629
protein modification process	GO:0036211	438	0.624
regulation of transport	GO:0051049	181	0.618
regulation of cell proliferation	GO:0042127	163	0.615	Mouse
positive regulation of biosynthetic process	GO:0009891	316	0.614
regulation of actin cytoskeleton organization	GO:0032956	42	0.605
wing disc morphogenesis	GO:0007472	344	0.599
respiratory system development	GO:0060541	213	0.580
regulation of developmental growth	GO:0048638	174	0.580
apoptotic process	GO:0006915	159	0.566
small molecule metabolic process	GO:0044281	305	0.561	Mouse
nuclear division	GO:0000280	332	0.556
positive regulation of developmental process	GO:0051094	143	0.555
nucleobase containing compound catabolic process	GO:0034655	165	0.554	Mouse
regulation of cellular protein metabolic process	GO:0032268	243	0.553
ovarian follicle cell development	GO:0030707	248	0.551
cell motility	GO:0048870	251	0.548	Human Mouse
actin filament based process	GO:0030029	220	0.547
intracellular signal transduction	GO:0035556	300	0.542
regulation of locomotion	GO:0040012	42	0.538	Mouse
photoreceptor cell development	GO:0042461	96	0.535
negative regulation of biosynthetic process	GO:0009890	277	0.534
multi organism behavior	GO:0051705	175	0.528
cell migration	GO:0016477	238	0.524	Mouse
regulation of synapse assembly	GO:0051963	94	0.521
glial cell differentiation	GO:0010001	35	0.519
regulation of apoptotic process	GO:0042981	130	0.517
cell substrate adhesion	GO:0031589	10	0.506	Mouse
oocyte development	GO:0048599	124	0.501
biological adhesion	GO:0022610	138	0.489	Mouse
reproductive behavior	GO:0019098	122	0.480
embryonic pattern specification	GO:0009880	174	0.476
vesicle mediated transport	GO:0016192	381	0.475	Human
regulation of actin filament based process	GO:0032970	42	0.474
regulation of cytoskeleton organization	GO:0051493	89	0.472
negative regulation of cell death	GO:0060548	81	0.467
single organism intracellular transport	GO:1902582	207	0.462	Human Mouse
organelle localization	GO:0051640	148	0.456
establishment or maintenance of cell polarity	GO:0007163	167	0.455	Human Mouse
response to external biotic stimulus	GO:0043207	293	0.447
regulation of dendrite morphogenesis	GO:0048814	28	0.441
negative regulation of response to stimulus	GO:0048585	258	0.439
translation	GO:0006412	69	0.437
protein phosphorylation	GO:0006468	169	0.433
cell recognition	GO:0008037	102	0.430
neurological system process	GO:0050877	358	0.428
tube development	GO:0035295	244	0.423
negative regulation of cell communication	GO:0010648	223	0.421
axon midline choice point recognition	GO:0016199	26	0.420
multicellular organismal reproductive behavior	GO:0033057	110	0.418
negative regulation of cellular metabolic process	GO:0031324	382	0.418
cellular macromolecule localization	GO:0070727	220	0.417	Human Mouse
regulation of synaptic growth at neuromuscular junction	GO:0008582	89	0.416
regulation of cellular component biogenesis	GO:0044087	201	0.397
organic cyclic compound catabolic process	GO:1901361	168	0.397	Mouse
dendrite development	GO:0016358	204	0.395
cellular nitrogen compound catabolic process	GO:0044270	165	0.394	Mouse
single organism cellular localization	GO:1902580	180	0.391	Human Mouse
cognition	GO:0050890	141	0.386
membrane organization	GO:0061024	112	0.386	Human Mouse
positive regulation of growth	GO:0045927	75	0.379
negative regulation of programmed cell death	GO:0043069	72	0.375
multi organism reproductive behavior	GO:0044705	121	0.375
negative regulation of nervous system development	GO:0051961	92	0.370
regulation of cellular ketone metabolic process	GO:0010565	3	0.364
positive regulation of multicellular organismal process	GO:0051240	143	0.359
heterocycle catabolic process	GO:0046700	166	0.356	Mouse
cellular protein localization	GO:0034613	160	0.353	Human Mouse
purine nucleoside triphosphate metabolic process	GO:0009144	119	0.351	Mouse
body morphogenesis	GO:0010171	2	0.346
cell death	GO:0008219	279	0.345
larval development	GO:0002164	104	0.339
gliogenesis	GO:0042063	80	0.338
epithelial cell development	GO:0002064	274	0.336
imaginal disc derived appendage development	GO:0048737	399	0.335
positive regulation of cellular biosynthetic process	GO:0031328	316	0.335
regulation of epithelial cell proliferation	GO:0050678	4	0.332
dorsal closure	GO:0007391	79	0.330
endocytosis	GO:0006897	310	0.328
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.324
developmental growth involved in morphogenesis	GO:0060560	65	0.318
positive regulation of developmental growth	GO:0048639	62	0.318
appendage morphogenesis	GO:0035107	397	0.316
spermatogenesis	GO:0007283	200	0.316
molting cycle	GO:0042303	56	0.315
intracellular transport	GO:0046907	228	0.309	Human Mouse
gonad development	GO:0008406	50	0.307
muscle cell development	GO:0055001	50	0.304
neuromuscular synaptic transmission	GO:0007274	67	0.300
cellular component assembly involved in morphogenesis	GO:0010927	151	0.299
photoreceptor cell axon guidance	GO:0072499	23	0.297
skin development	GO:0043588	65	0.297
regulation of cellular component size	GO:0032535	98	0.295
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.291
regulation of intracellular signal transduction	GO:1902531	236	0.290
cellular ketone metabolic process	GO:0042180	24	0.285
organelle assembly	GO:0070925	198	0.283
synaptic transmission	GO:0007268	288	0.282
programmed cell death	GO:0012501	257	0.277
positive regulation of phosphate metabolic process	GO:0045937	139	0.275
olfactory learning	GO:0008355	56	0.274
regulation of cell differentiation	GO:0045595	302	0.274
compound eye photoreceptor development	GO:0042051	78	0.273
regulation of neuron differentiation	GO:0045664	103	0.271
cell proliferation	GO:0008283	299	0.267	Mouse
single organism membrane organization	GO:0044802	93	0.266	Human Mouse
telencephalon development	GO:0021537	2	0.265
protein polymerization	GO:0051258	42	0.264
posttranscriptional regulation of gene expression	GO:0010608	145	0.263
regulation of organelle organization	GO:0033043	196	0.258
positive regulation of response to stimulus	GO:0048584	323	0.253	Mouse
regulation of mitotic cell cycle	GO:0007346	190	0.251
regulation of programmed cell death	GO:0043067	152	0.250
kidney development	GO:0001822	3	0.249
reproductive structure development	GO:0048608	74	0.248
negative regulation of developmental growth	GO:0048640	64	0.248
cell cell signaling involved in cell fate commitment	GO:0045168	210	0.244
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.242
single organismal cell cell adhesion	GO:0016337	45	0.242
localization of cell	GO:0051674	257	0.240	Human Mouse
regulation of phosphate metabolic process	GO:0019220	210	0.239
single organism behavior	GO:0044708	391	0.239
male gamete generation	GO:0048232	201	0.238
positive regulation of protein complex assembly	GO:0031334	22	0.238
tripartite regional subdivision	GO:0007351	103	0.234
positive regulation of neurogenesis	GO:0050769	41	0.230
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.230
positive regulation of cell growth	GO:0030307	19	0.230
regulation of phosphorus metabolic process	GO:0051174	210	0.228
transcription from rna polymerase ii promoter	GO:0006366	368	0.227
branching involved in open tracheal system development	GO:0060446	45	0.223
establishment of protein localization to plasma membrane	GO:0090002	9	0.222	Human
regulation of phosphorylation	GO:0042325	147	0.219
positive regulation of cellular component organization	GO:0051130	156	0.218
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.217
apposition of dorsal and ventral imaginal disc derived wing surfaces	GO:0007475	15	0.217
regulation of cell death	GO:0010941	173	0.213
heart development	GO:0007507	82	0.208
positive regulation of cell differentiation	GO:0045597	64	0.204
rhythmic process	GO:0048511	106	0.204
skeletal muscle organ development	GO:0060538	48	0.198
macromolecule catabolic process	GO:0009057	161	0.197
actin polymerization or depolymerization	GO:0008154	31	0.193
multicellular organism growth	GO:0035264	46	0.192
organic substance transport	GO:0071702	257	0.186	Human Mouse
embryo development ending in birth or egg hatching	GO:0009792	152	0.183
positive regulation of cell development	GO:0010720	61	0.183
epithelial cell migration	GO:0010631	148	0.183	Mouse
single organism cell adhesion	GO:0098602	47	0.180
positive regulation of phosphorus metabolic process	GO:0010562	139	0.179
cardiovascular system development	GO:0072358	82	0.178
ribonucleoside triphosphate metabolic process	GO:0009199	119	0.176	Mouse
regulation of cell development	GO:0060284	215	0.176
organelle fission	GO:0048285	340	0.171
cytoplasmic transport	GO:0016482	130	0.168	Human Mouse
establishment of protein localization	GO:0045184	163	0.168	Human Mouse
digestive system development	GO:0055123	149	0.166	Mouse
regulation of purine nucleotide catabolic process	GO:0033121	48	0.165
meiotic nuclear division	GO:0007126	151	0.164
regulation of protein complex assembly	GO:0043254	42	0.163
aromatic compound catabolic process	GO:0019439	166	0.162	Mouse
regulation of secretion	GO:0051046	44	0.162
regulation of vesicle mediated transport	GO:0060627	59	0.160
actin filament organization	GO:0007015	126	0.159
negative regulation of rna biosynthetic process	GO:1902679	240	0.158
eye morphogenesis	GO:0048592	260	0.156
lateral inhibition	GO:0046331	206	0.154
columnar cuboidal epithelial cell differentiation	GO:0002065	256	0.154
regulation of cell projection organization	GO:0031344	92	0.154
catabolic process	GO:0009056	409	0.152	Mouse
axonal fasciculation	GO:0007413	12	0.150
regulation of protein polymerization	GO:0032271	28	0.147
immune system development	GO:0002520	57	0.147
morphogenesis of a branching structure	GO:0001763	45	0.146
regulation of anatomical structure size	GO:0090066	163	0.145
regulation of actin polymerization or depolymerization	GO:0008064	27	0.143
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.142
gene silencing	GO:0016458	138	0.141
nucleus localization	GO:0051647	34	0.141
actomyosin structure organization	GO:0031032	56	0.138
nucleotide metabolic process	GO:0009117	161	0.137	Mouse
regulation of secretion by cell	GO:1903530	39	0.136
organonitrogen compound metabolic process	GO:1901564	318	0.136	Mouse
peptidyl amino acid modification	GO:0018193	105	0.135
nucleotide catabolic process	GO:0009166	109	0.134	Mouse
glycosyl compound catabolic process	GO:1901658	112	0.134	Mouse
protein localization to plasma membrane	GO:0072659	13	0.133	Human
positive regulation of protein polymerization	GO:0032273	14	0.131
wnt signaling pathway	GO:0016055	98	0.130	Mouse
homeostatic process	GO:0042592	199	0.130
compound eye development	GO:0048749	307	0.128
establishment of organelle localization	GO:0051656	122	0.128
development of primary sexual characteristics	GO:0045137	50	0.127
negative regulation of gene expression	GO:0010629	387	0.127
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	65	0.123
secretion by cell	GO:0032940	101	0.123
dorsal ventral axon guidance	GO:0033563	2	0.122
germarium derived egg chamber formation	GO:0007293	101	0.121
positive regulation of cellular component biogenesis	GO:0044089	80	0.121
negative regulation of apoptotic process	GO:0043066	63	0.120
ribonucleoside catabolic process	GO:0042454	112	0.119	Mouse
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	116	0.118
neuromuscular junction development	GO:0007528	149	0.118
negative regulation of cellular component organization	GO:0051129	108	0.118
striated muscle myosin thick filament assembly	GO:0071688	3	0.114
purine nucleoside metabolic process	GO:0042278	127	0.113	Mouse
meiotic cell cycle process	GO:1903046	132	0.112
myofibril assembly	GO:0030239	36	0.112
establishment of nucleus localization	GO:0040023	26	0.112
signal transduction by phosphorylation	GO:0023014	107	0.110
dorsal ventral axis specification	GO:0009950	66	0.109
response to biotic stimulus	GO:0009607	294	0.109
positive regulation of catalytic activity	GO:0043085	118	0.109
mitotic nuclear division	GO:0007067	213	0.107
regulation of response to stress	GO:0080134	200	0.106
positive regulation of signal transduction	GO:0009967	223	0.105	Mouse
learning or memory	GO:0007611	141	0.104
negative regulation of signal transduction	GO:0009968	206	0.103
negative regulation of synapse assembly	GO:0051964	39	0.102
proteolysis	GO:0006508	192	0.101
establishment of protein localization to membrane	GO:0090150	11	0.100	Human Mouse
oocyte axis specification	GO:0007309	108	0.099
positive regulation of molecular function	GO:0044093	136	0.099
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.095
positive regulation of cell migration	GO:0030335	2	0.095
regulation of catalytic activity	GO:0050790	185	0.094
regulation of microtubule cytoskeleton organization	GO:0070507	41	0.094
cellular catabolic process	GO:0044248	372	0.093	Mouse
neuron projection extension	GO:1990138	32	0.092
regulation of small gtpase mediated signal transduction	GO:0051056	93	0.090
nucleoside phosphate catabolic process	GO:1901292	110	0.089	Mouse
sensory organ morphogenesis	GO:0090596	260	0.088
oviposition	GO:0018991	19	0.087
nucleoside catabolic process	GO:0009164	112	0.087	Mouse
actin filament bundle organization	GO:0061572	28	0.086
central nervous system development	GO:0007417	201	0.085
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.085
reproductive system development	GO:0061458	74	0.084
cell division	GO:0051301	248	0.083
negative regulation of signaling	GO:0023057	219	0.083
positive regulation of cellular amino acid metabolic process	GO:0045764	0	0.082
hindbrain development	GO:0030902	2	0.082
neuron recognition	GO:0008038	101	0.081
actin filament polymerization	GO:0030041	27	0.081
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.079
defense response	GO:0006952	300	0.078
carbohydrate derivative metabolic process	GO:1901135	217	0.078	Mouse
ras protein signal transduction	GO:0007265	88	0.078
plasma membrane organization	GO:0007009	26	0.077	Human
negative regulation of multicellular organismal process	GO:0051241	142	0.077
head development	GO:0060322	135	0.076
epithelium migration	GO:0090132	148	0.076	Mouse
regulation of cell cycle process	GO:0010564	181	0.076
striated muscle cell development	GO:0055002	50	0.076
regulation of neuron projection development	GO:0010975	69	0.075
amine metabolic process	GO:0009308	12	0.074
regulation of protein phosphorylation	GO:0001932	64	0.074
regulation of translation	GO:0006417	56	0.073
negative regulation of cell proliferation	GO:0008285	69	0.073	Mouse
gland morphogenesis	GO:0022612	145	0.072
rho protein signal transduction	GO:0007266	14	0.071
defense response to other organism	GO:0098542	225	0.071
negative regulation of cell development	GO:0010721	62	0.070
purine nucleotide catabolic process	GO:0006195	109	0.070	Mouse
positive regulation of cytoskeleton organization	GO:0051495	21	0.070
positive regulation of cell communication	GO:0010647	250	0.070	Mouse
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.069
regulation of ras protein signal transduction	GO:0046578	93	0.069
cell adhesion	GO:0007155	136	0.069	Mouse
developmental cell growth	GO:0048588	52	0.068
neuron migration	GO:0001764	5	0.067
mrna metabolic process	GO:0016071	124	0.067
protein catabolic process	GO:0030163	101	0.066
mapk cascade	GO:0000165	107	0.066
associative learning	GO:0008306	65	0.065
regulation of mapk cascade	GO:0043408	92	0.065
actin cytoskeleton reorganization	GO:0031532	22	0.065
maintenance of location	GO:0051235	73	0.064
positive regulation of cell motility	GO:2000147	3	0.063
regulation of actin filament length	GO:0030832	27	0.063
heart morphogenesis	GO:0003007	32	0.062
purine nucleoside triphosphate catabolic process	GO:0009146	108	0.061	Mouse
neuronal action potential	GO:0019228	10	0.060
eye photoreceptor cell development	GO:0042462	81	0.060
morphogenesis of a branching epithelium	GO:0061138	45	0.059
organic substance catabolic process	GO:1901575	308	0.059	Mouse
nerve development	GO:0021675	6	0.059
epidermis development	GO:0008544	65	0.059
regulation of tube size	GO:0035150	46	0.059
carbohydrate derivative catabolic process	GO:1901136	118	0.059	Mouse
regulation of dendrite development	GO:0050773	37	0.058
regulation of multicellular organism growth	GO:0040014	40	0.058
purine ribonucleoside triphosphate metabolic process	GO:0009205	119	0.058	Mouse
sex differentiation	GO:0007548	81	0.058
eye development	GO:0001654	323	0.057
response to bacterium	GO:0009617	198	0.057
response to abiotic stimulus	GO:0009628	341	0.057
negative regulation of neurogenesis	GO:0050768	53	0.056
stress activated mapk cascade	GO:0051403	52	0.054
regulation of hydrolase activity	GO:0051336	97	0.054
digestive tract development	GO:0048565	149	0.054	Mouse
negative regulation of cellular protein metabolic process	GO:0032269	85	0.053
genitalia development	GO:0048806	26	0.052
regulation of cell size	GO:0008361	63	0.052
purine containing compound metabolic process	GO:0072521	155	0.051	Mouse
stress activated protein kinase signaling cascade	GO:0031098	55	0.050
purine nucleoside monophosphate metabolic process	GO:0009126	50	0.050	Mouse
cell fate determination	GO:0001709	91	0.050
positive regulation of signaling	GO:0023056	243	0.050	Mouse
immune response	GO:0006955	246	0.050
microtubule based transport	GO:0010970	42	0.049	Mouse
border follicle cell migration	GO:0007298	113	0.049
ameboidal type cell migration	GO:0001667	151	0.049	Mouse
protein localization to membrane	GO:0072657	19	0.049	Human Mouse
response to organic substance	GO:0010033	284	0.049
meiotic chromosome segregation	GO:0045132	59	0.049
neuromuscular process	GO:0050905	21	0.049
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.048
anatomical structure homeostasis	GO:0060249	97	0.047
locomotory behavior	GO:0007626	176	0.047
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090100	9	0.046
regulation of protein modification process	GO:0031399	112	0.046
organophosphate metabolic process	GO:0019637	195	0.045	Mouse
protein transport	GO:0015031	155	0.045	Human Mouse
oxoacid metabolic process	GO:0043436	103	0.045
regulation of actin filament polymerization	GO:0030833	25	0.045
stem cell proliferation	GO:0072089	88	0.044
positive regulation of mapk cascade	GO:0043410	63	0.044
small gtpase mediated signal transduction	GO:0007264	88	0.044
positive regulation of actin filament polymerization	GO:0030838	11	0.044
positive regulation of axonogenesis	GO:0050772	2	0.044
regulation of establishment of protein localization	GO:0070201	61	0.043
anterior posterior axis specification embryo	GO:0008595	103	0.043
meiotic cell cycle	GO:0051321	171	0.043
multicellular organismal signaling	GO:0035637	12	0.042
regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090092	38	0.042
establishment or maintenance of microtubule cytoskeleton polarity	GO:0030951	41	0.041
purine ribonucleoside triphosphate catabolic process	GO:0009207	108	0.041	Mouse
negative regulation of epithelial cell proliferation	GO:0050680	4	0.041
nephron development	GO:0072006	3	0.040
regulation of cell morphogenesis	GO:0022604	163	0.040
organic acid metabolic process	GO:0006082	103	0.040
regulation of molecular function	GO:0065009	217	0.040
embryonic axis specification	GO:0000578	107	0.040
nucleoside triphosphate catabolic process	GO:0009143	108	0.040	Mouse
regulation of jnk cascade	GO:0046328	40	0.039
regulation of anatomical structure morphogenesis	GO:0022603	242	0.039
substrate adhesion dependent cell spreading	GO:0034446	2	0.039
purine nucleoside catabolic process	GO:0006152	112	0.039	Mouse
detection of chemical stimulus	GO:0009593	93	0.039
purine containing compound catabolic process	GO:0072523	112	0.038	Mouse
phagocytosis	GO:0006909	215	0.038
cell cycle phase transition	GO:0044770	140	0.038
response to other organism	GO:0051707	293	0.038
positive regulation of neuron differentiation	GO:0045666	26	0.038
negative regulation of developmental process	GO:0051093	201	0.037
protein localization to nucleus	GO:0034504	55	0.037
positive regulation of purine nucleotide catabolic process	GO:0033123	46	0.037
negative regulation of catalytic activity	GO:0043086	42	0.037
negative regulation of neural precursor cell proliferation	GO:2000178	27	0.037
response to wounding	GO:0009611	94	0.036	Human Mouse
columnar cuboidal epithelial cell development	GO:0002066	249	0.036
cellular cation homeostasis	GO:0030003	38	0.036
exocytosis	GO:0006887	28	0.036
regulation of sequestering of calcium ion	GO:0051282	3	0.036
regulation of proteolysis	GO:0030162	87	0.035
detection of stimulus involved in sensory perception	GO:0050906	92	0.035
single organism biosynthetic process	GO:0044711	206	0.035
purine ribonucleotide catabolic process	GO:0009154	109	0.035	Mouse
lipid storage	GO:0019915	38	0.035
germarium derived oocyte fate determination	GO:0007294	26	0.035
striated muscle contraction	GO:0006941	5	0.034
establishment of cell polarity	GO:0030010	40	0.034
regulation of gliogenesis	GO:0014013	11	0.034
retinal ganglion cell axon guidance	GO:0031290	12	0.033
regulation of stress activated protein kinase signaling cascade	GO:0070302	42	0.033
epithelial tube morphogenesis	GO:0060562	88	0.033
response to nitrogen compound	GO:1901698	90	0.033
renal system development	GO:0072001	72	0.033
positive regulation of protein metabolic process	GO:0051247	128	0.032
organonitrogen compound catabolic process	GO:1901565	128	0.032	Mouse
negative regulation of rho protein signal transduction	GO:0035024	1	0.032
single organism catabolic process	GO:0044712	228	0.032	Mouse
organophosphate catabolic process	GO:0046434	112	0.031	Mouse
cardiocyte differentiation	GO:0035051	29	0.031
regulation of cellular response to stress	GO:0080135	89	0.031
neuron maturation	GO:0042551	31	0.031
regulation of cellular amino acid metabolic process	GO:0006521	0	0.031
chorion containing eggshell formation	GO:0007304	105	0.030
dorsal appendage formation	GO:0046843	47	0.030
negative regulation of protein metabolic process	GO:0051248	85	0.030
positive regulation of lipid metabolic process	GO:0045834	4	0.030
cellular amino acid metabolic process	GO:0006520	61	0.030
oocyte fate determination	GO:0030716	27	0.030
carboxylic acid metabolic process	GO:0019752	92	0.030
positive regulation of cell projection organization	GO:0031346	29	0.030
ovarian follicle cell migration	GO:0007297	121	0.029
regulation of nucleoside metabolic process	GO:0009118	50	0.029
regulation of imaginal disc growth	GO:0045570	26	0.029
negative regulation of mitotic cell cycle phase transition	GO:1901991	103	0.029
muscle tissue development	GO:0060537	30	0.028
positive regulation of transcription dna templated	GO:0045893	266	0.028
cell projection assembly	GO:0030031	94	0.028
negative regulation of synaptic growth at neuromuscular junction	GO:0045886	39	0.028
anterior posterior axis specification	GO:0009948	109	0.028
humoral immune response	GO:0006959	117	0.028
wound healing	GO:0042060	75	0.028	Mouse
dorsal trunk growth open tracheal system	GO:0035001	7	0.028
somatic muscle development	GO:0007525	66	0.027
regionalization	GO:0003002	416	0.027
cellular response to dna damage stimulus	GO:0006974	223	0.027
nucleoside phosphate metabolic process	GO:0006753	162	0.027	Mouse
positive regulation of cell proliferation	GO:0008284	47	0.027
axonal defasciculation	GO:0007414	12	0.026
blastoderm segmentation	GO:0007350	159	0.026
establishment of protein localization to organelle	GO:0072594	62	0.026	Mouse
response to oxygen containing compound	GO:1901700	200	0.026
tissue migration	GO:0090130	155	0.026	Mouse
positive regulation of protein phosphorylation	GO:0001934	34	0.026
secretion	GO:0046903	109	0.026
regulation of cellular amine metabolic process	GO:0033238	3	0.026
cell growth	GO:0016049	108	0.026
cellular amine metabolic process	GO:0044106	12	0.025
ribonucleotide metabolic process	GO:0009259	145	0.025	Mouse
cellular macromolecule catabolic process	GO:0044265	136	0.025
multicellular organismal homeostasis	GO:0048871	41	0.025
brain development	GO:0007420	120	0.025
regulation of cell migration	GO:0030334	22	0.024	Mouse
spinal cord development	GO:0021510	1	0.024
imaginal disc growth	GO:0007446	37	0.024
lipid localization	GO:0010876	54	0.024

shot disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability	Func Analog Org
disease of anatomical entity	DOID:7	0.355	Human
benign neoplasm	DOID:0060072	0.139
disease of cellular proliferation	DOID:14566	0.139
cardiovascular system disease	DOID:1287	0.072

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