Drosophila melanogaster

97 known processes

dre4 (Dmel_CG1828)

CG1828 gene product from transcript CG1828-RB

(Aliases: DRE4/dSPT16,CG1828,Spt16,dSPT16,spt16,dSpt16,dspt16,l(3)dre4,Dmel\CG1828,l(3)62Bg)

dre4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cell cycle checkpointGO:0000075950.697
mitotic dna damage checkpointGO:0044773740.681
positive regulation of rna metabolic processGO:00512542710.536
dna damage checkpointGO:0000077780.520
positive regulation of nitrogen compound metabolic processGO:00511733540.505
negative regulation of cell cycleGO:00457861160.494
negative regulation of mitotic cell cycle phase transitionGO:19019911030.492
embryo development ending in birth or egg hatchingGO:00097921520.483
Worm
cellular response to dna damage stimulusGO:00069742230.460
male gamete generationGO:00482322010.389
cell cycle phase transitionGO:00447701400.389
g2 dna damage checkpointGO:0031572690.374
mitotic cell cycle checkpointGO:0007093880.310
dna metabolic processGO:00062592270.296
negative regulation of cell cycle phase transitionGO:19019881030.296
negative regulation of mitotic cell cycleGO:00459301090.293
negative regulation of gene expressionGO:00106293870.281
cellular protein modification processGO:00064644380.266
mitotic cell cycle phase transitionGO:00447721380.257
negative regulation of biosynthetic processGO:00098902770.244
protein modification by small protein conjugation or removalGO:00706471060.213
positive regulation of gene expressionGO:00106282900.204
regulation of cell cycle phase transitionGO:19019871300.197
spermatogenesisGO:00072832000.196
regionalizationGO:00030024160.196
larval developmentGO:00021641040.194
sister chromatid segregationGO:0000819920.193
protein complex assemblyGO:00064612000.186
negative regulation of transcription dna templatedGO:00458922370.171
protein transportGO:00150311550.165
positive regulation of cellular biosynthetic processGO:00313283160.163
dna repairGO:0006281540.162
determination of adult lifespanGO:00083401370.162
establishment or maintenance of cell polarityGO:00071631670.161
regulation of mitotic cell cycle phase transitionGO:19019901300.158
spermatid differentiationGO:00485151140.158
proteolysisGO:00065081920.157
mitotic g2 m transition checkpointGO:0044818700.152
macromolecular complex assemblyGO:00650032560.151
protein ubiquitinationGO:0016567700.149
vesicle mediated transportGO:00161923810.146
organelle assemblyGO:00709251980.145
cellular protein localizationGO:00346131600.141
growthGO:00400073590.140
dna integrity checkpointGO:0031570810.139
regulation of cell cycle processGO:00105641810.131
regulation of dna templated transcription elongationGO:0032784170.130
agingGO:00075681430.129
positive regulation of macromolecule biosynthetic processGO:00105572830.129
negative regulation of cell cycle processGO:00109481090.122
gene silencingGO:00164581380.119
mitotic dna integrity checkpointGO:0044774750.117
cell migrationGO:00164772380.116
immune system processGO:00023763470.113
negative regulation of macromolecule biosynthetic processGO:00105582700.113
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.113
apoptotic processGO:00069151590.111
developmental maturationGO:00217001720.110
embryonic development via the syncytial blastodermGO:00017001480.107
protein maturationGO:0051604710.105
regulation of cellular localizationGO:00603411360.104
negative regulation of cellular metabolic processGO:00313243820.101
protein localizationGO:00081042840.101
single organism cellular localizationGO:19025801800.099
nucleobase containing small molecule metabolic processGO:00550861740.096
negative regulation of nucleobase containing compound metabolic processGO:00459342610.095
spermatid developmentGO:0007286980.094
regulation of neurogenesisGO:00507671580.094
regulation of molecular functionGO:00650092170.092
regulation of gene expression epigeneticGO:00400291280.091
purine nucleoside metabolic processGO:00422781270.091
purine containing compound catabolic processGO:00725231120.088
protein complex biogenesisGO:00702712010.088
cell maturationGO:00484691440.087
reproductive system developmentGO:0061458740.087
body morphogenesisGO:001017120.085
mrna splice site selectionGO:000637610.080
protein modification by small protein conjugationGO:0032446790.079
embryonic morphogenesisGO:00485982060.078
mitotic g2 dna damage checkpointGO:0007095690.077
positive regulation of rna biosynthetic processGO:19026802660.077
positive regulation of nucleobase containing compound metabolic processGO:00459353320.077
protein processingGO:0016485680.076
multicellular organismal agingGO:00102591400.076
regulation of developmental growthGO:00486381740.074
multicellular organism growthGO:0035264460.073
positive regulation of signal transductionGO:00099672230.071
dna templated transcription elongationGO:0006354180.070
protein catabolic processGO:00301631010.070
chromatin organizationGO:00063252070.069
ribose phosphate metabolic processGO:00196931450.069
negative regulation of cellular biosynthetic processGO:00313272770.069
cellular macromolecule catabolic processGO:00442651360.068
negative regulation of nitrogen compound metabolic processGO:00511722650.067
protein modification processGO:00362114380.066
glycosyl compound catabolic processGO:19016581120.064
embryonic pattern specificationGO:00098801740.064
cell proliferationGO:00082832990.062
developmental programmed cell deathGO:00106231380.062
cellular macromolecular complex assemblyGO:00346221530.060
negative regulation of developmental processGO:00510932010.060
purine nucleoside triphosphate catabolic processGO:00091461080.060
protein importGO:0017038550.058
regulation of proteolysisGO:0030162870.058
positive regulation of proteolysisGO:0045862520.057
establishment of localization in cellGO:00516494020.057
phosphorylationGO:00163102940.056
meiotic cell cycleGO:00513211710.055
regulation of cellular protein metabolic processGO:00322682430.055
positive regulation of macromolecule metabolic processGO:00106044050.055
regulation of mitotic cell cycleGO:00073461900.055
single organism intracellular transportGO:19025822070.054
chromosome organizationGO:00512763600.054
organonitrogen compound metabolic processGO:19015643180.054
programmed cell deathGO:00125012570.053
negative regulation of nucleic acid templated transcriptionGO:19035072400.053
posttranscriptional gene silencing by rnaGO:0035194450.051
sex differentiationGO:0007548810.051
cytoskeleton dependent cytokinesisGO:0061640810.051
genitalia developmentGO:0048806260.051
imaginal disc derived wing morphogenesisGO:00074763370.051
ubiquitin dependent protein catabolic processGO:0006511780.050
mitotic sister chromatid segregationGO:0000070870.050
developmental growthGO:00485892800.050
nucleoside metabolic processGO:00091161270.049
purine containing compound metabolic processGO:00725211550.049
regulation of meiosisGO:004002030.048
spindle organizationGO:00070512530.048
notch signaling pathwayGO:00072191200.048
zymogen activationGO:0031638200.048
purine ribonucleoside metabolic processGO:00461281270.047
modification dependent macromolecule catabolic processGO:0043632790.047
deathGO:00162652840.047
axon developmentGO:00615642970.046
activation of cysteine type endopeptidase activityGO:0097202170.045
cell motilityGO:00488702510.045
mrna processingGO:00063971040.045
heterocycle catabolic processGO:00467001660.045
cellular catabolic processGO:00442483720.045
macromolecule catabolic processGO:00090571610.045
cellular protein complex assemblyGO:0043623710.043
positive regulation of catabolic processGO:00098961050.041
activation of cysteine type endopeptidase activity involved in apoptotic processGO:0006919160.041
catabolic processGO:00090564090.041
positive regulation of peptidase activityGO:0010952290.040
histone mrna metabolic processGO:000833480.040
positive regulation of immune responseGO:0050778630.040
reproductive structure developmentGO:0048608740.040
regulation of small gtpase mediated signal transductionGO:0051056930.039
positive regulation of biosynthetic processGO:00098913160.039
regulation of cellular component biogenesisGO:00440872010.039
intracellular transportGO:00469072280.039
positive regulation of signalingGO:00230562430.039
stem cell differentiationGO:00488631170.038
protein dna complex subunit organizationGO:0071824860.038
positive regulation of immune system processGO:0002684680.038
positive regulation of molecular functionGO:00440931360.038
dendrite developmentGO:00163582040.038
compound eye photoreceptor cell differentiationGO:00017511400.038
spindle assembly involved in mitosisGO:0090307500.037
multicellular organismal reproductive behaviorGO:00330571100.037
nucleoside phosphate metabolic processGO:00067531620.036
transcription from rna polymerase ii promoterGO:00063663680.036
negative regulation of rna biosynthetic processGO:19026792400.035
protein modification by small protein removalGO:0070646280.035
cellular macromolecule localizationGO:00707272200.035
purine nucleotide metabolic processGO:00061631460.035
endocytosisGO:00068973100.035
proteolysis involved in cellular protein catabolic processGO:0051603830.035
multi organism behaviorGO:00517051750.035
purine nucleoside catabolic processGO:00061521120.034
regulation of multi organism processGO:00439001310.034
regulation of cell cycleGO:00517262910.034
regulation of cell differentiationGO:00455953020.034
regulation of multicellular organism growthGO:0040014400.033
rna splicing via transesterification reactionsGO:0000375730.033
intracellular signal transductionGO:00355563000.033
hemopoiesisGO:0030097460.033
cell divisionGO:00513012480.032
multi multicellular organism processGO:00447061230.032
modification dependent protein catabolic processGO:0019941780.032
ribonucleoside catabolic processGO:00424541120.032
humoral immune responseGO:00069591170.032
establishment of organelle localizationGO:00516561220.032
positive regulation of catalytic activityGO:00430851180.031
positive regulation of developmental growthGO:0048639620.031
molting cycleGO:0042303560.030
Worm
cellular protein catabolic processGO:0044257830.030
gonad developmentGO:0008406500.030
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161540.030
rna processingGO:00063961470.030
synapse organizationGO:00508081960.029
cellular response to lipopolysaccharideGO:007122230.029
organic substance catabolic processGO:19015753080.029
nucleoside triphosphate metabolic processGO:00091411200.029
mrna splicing via spliceosomeGO:0000398730.029
chromosome segregationGO:00070591570.029
small gtpase mediated signal transductionGO:0007264880.028
mrna metabolic processGO:00160711240.028
establishment of protein localizationGO:00451841630.028
positive regulation of nucleic acid templated transcriptionGO:19035082660.028
positive regulation of cell communicationGO:00106472500.028
carbohydrate derivative metabolic processGO:19011352170.027
organelle fissionGO:00482853400.027
cytoplasmic transportGO:00164821300.027
cellular nitrogen compound catabolic processGO:00442701650.026
epithelial cell developmentGO:00020642740.026
purine ribonucleotide metabolic processGO:00091501450.026
chromatin modificationGO:00165681470.026
posttranscriptional regulation of gene expressionGO:00106081450.026
cellular protein complex disassemblyGO:0043624350.026
appendage morphogenesisGO:00351073970.026
morphogenesis of an epitheliumGO:00020092760.026
protein dna complex assemblyGO:0065004630.025
protein targeting to nucleusGO:0044744510.025
protein deubiquitinationGO:0016579170.025
covalent chromatin modificationGO:00165691060.025
proteasomal protein catabolic processGO:0010498590.025
regulation of immune system processGO:00026821760.025
regulation of notch signaling pathwayGO:00085931000.025
purine ribonucleoside triphosphate catabolic processGO:00092071080.025
protein targetingGO:0006605640.025
organonitrogen compound catabolic processGO:19015651280.024
regulation of phosphorylationGO:00423251470.024
ribonucleoside triphosphate metabolic processGO:00091991190.024
intracellular protein transportGO:00068861040.024
necrotic cell deathGO:007026510.024
regulation of catalytic activityGO:00507901850.024
regulation of intracellular signal transductionGO:19025312360.024
mrna catabolic processGO:0006402330.024
positive regulation of protein metabolic processGO:00512471280.023
regulation of protein transportGO:0051223570.023
axis specificationGO:00097981670.023
regulation of phosphorus metabolic processGO:00511742100.023
response to oxidative stressGO:0006979860.023
small molecule metabolic processGO:00442813050.022
positive regulation of endopeptidase activityGO:0010950260.022
carbohydrate derivative catabolic processGO:19011361180.022
spliceosomal complex assemblyGO:000024510.022
ribonucleotide catabolic processGO:00092611090.022
axonogenesisGO:00074092900.022
nucleoside catabolic processGO:00091641120.022
germarium derived egg chamber formationGO:00072931010.022
eye photoreceptor cell differentiationGO:00017541450.022
ras protein signal transductionGO:0007265880.021
multi organism reproductive behaviorGO:00447051210.021
development of primary sexual characteristicsGO:0045137500.021
negative regulation of neuroblast proliferationGO:0007406270.021
regulation of protein complex disassemblyGO:0043244290.021
positive regulation of response to stimulusGO:00485843230.021
neuroblast proliferationGO:0007405740.021
nucleobase containing compound catabolic processGO:00346551650.021
postreplication repairGO:000630120.020
regulation of multicellular organismal developmentGO:20000264140.020
stem cell developmentGO:0048864790.020
phagocytosisGO:00069092150.020
ribonucleoside metabolic processGO:00091191270.020
regulation of programmed cell deathGO:00430671520.020
organophosphate metabolic processGO:00196371950.020
mitotic nuclear divisionGO:00070672130.019
gene silencing by rnaGO:0031047570.019
rna splicingGO:0008380830.019
regulation of transcription from rna polymerase ii promoterGO:00063573780.019
tissue morphogenesisGO:00487292970.019
aromatic compound catabolic processGO:00194391660.018
establishment of protein localization to organelleGO:0072594620.018
negative regulation of rna metabolic processGO:00512532510.018
regulation of protein modification processGO:00313991120.018
posttranscriptional gene silencingGO:0016441460.018
regulation of immune responseGO:00507761180.018
negative regulation of proteasomal protein catabolic processGO:1901799160.018
regulation of cellular ketone metabolic processGO:001056530.018
glycosyl compound metabolic processGO:19016571270.018
regulation of protein metabolic processGO:00512462560.018
regulation of cell deathGO:00109411730.018
regulation of catabolic processGO:00098941700.018
regulation of response to stressGO:00801342000.018
positive regulation of hydrolase activityGO:0051345780.017
regulation of phosphate metabolic processGO:00192202100.017
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280230.017
camera type eye developmentGO:004301040.017
double strand break repairGO:0006302260.017
regulation of protein localizationGO:0032880760.017
localization of cellGO:00516742570.017
ovarian follicle cell developmentGO:00307072480.016
receptor mediated endocytosisGO:0006898210.016
defense response to other organismGO:00985422250.016
cellular component disassemblyGO:0022411460.016
nuclear divisionGO:00002803320.016
rna interferenceGO:0016246270.016
organic substance transportGO:00717022570.016
positive regulation of cellular component organizationGO:00511301560.016
stem cell maintenanceGO:0019827670.015
ribonucleoside monophosphate metabolic processGO:0009161510.015
negative regulation of intrinsic apoptotic signaling pathwayGO:200124310.015
positive regulation of transcription dna templatedGO:00458932660.015
protein localization to organelleGO:0033365820.015
regulation of protein catabolic processGO:0042176550.015
defense response to bacteriumGO:00427421780.015
cellular amine metabolic processGO:0044106120.015
regulation of mrna metabolic processGO:1903311720.015
purine nucleoside triphosphate metabolic processGO:00091441190.015
blastoderm segmentationGO:00073501590.015
peptidyl amino acid modificationGO:00181931050.015
hematopoietic or lymphoid organ developmentGO:0048534570.015
alternative mrna splicing via spliceosomeGO:0000380600.015
purine ribonucleoside catabolic processGO:00461301120.014
rna 3 end processingGO:0031123450.014
microtubule organizing center organizationGO:00310231680.014
anterior posterior axis specificationGO:00099481090.014
regulation of response to external stimulusGO:00321011150.014
cellular response to molecule of bacterial originGO:007121930.014
mitotic cytokinesisGO:0000281500.014
molting cycle chitin based cuticleGO:0007591560.014
nuclear rna surveillanceGO:007102730.014
negative regulation of protein complex disassemblyGO:0043242230.014
neuron projection guidanceGO:00974852410.013
negative regulation of cellular catabolic processGO:0031330340.013
positive regulation of intracellular signal transductionGO:19025331160.013
regulation of cellular amino acid metabolic processGO:000652100.013
response to biotic stimulusGO:00096072940.013
lipid localizationGO:0010876540.013
regulation of protein localization to nucleusGO:1900180290.013
appendage developmentGO:00487364010.013
response to oxygen containing compoundGO:19017002000.013
ncrna metabolic processGO:0034660430.013
regulation of g2 m transition of mitotic cell cycleGO:0010389150.013
negative regulation of sister chromatid segregationGO:0033046130.013
enzyme linked receptor protein signaling pathwayGO:00071671790.013
cytokinesisGO:0000910900.013
maternal determination of anterior posterior axis embryoGO:0008358740.013
regulation of hydrolase activityGO:0051336970.013
actin filament based processGO:00300292200.013
positive regulation of protein transportGO:0051222370.012
imaginal disc derived appendage morphogenesisGO:00351143950.012
nuclear importGO:0051170510.012
negative regulation of response to stimulusGO:00485852580.012
columnar cuboidal epithelial cell developmentGO:00020662490.012
regulation of meiotic cell cycleGO:005144590.012
regulation of localizationGO:00328792750.012
tripartite regional subdivisionGO:00073511030.012
protein localization to nucleusGO:0034504550.012
columnar cuboidal epithelial cell differentiationGO:00020652560.012
negative regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032435160.012
mitotic spindle organizationGO:00070522200.012
positive regulation of growthGO:0045927750.012
response to abiotic stimulusGO:00096283410.011
response to external biotic stimulusGO:00432072930.011
cell deathGO:00082192790.011
histone h3 k4 methylationGO:0051568160.011
neuron maturationGO:0042551310.011
cellular response to biotic stimulusGO:007121640.011
photoreceptor cell differentiationGO:00465301700.011
nucleosome assemblyGO:0006334350.011
negative regulation of neural precursor cell proliferationGO:2000178270.011
positive regulation of protein import into nucleusGO:0042307210.011
ribonucleoprotein complex subunit organizationGO:0071826280.011
ovipositionGO:0018991190.011
eye developmentGO:00016543230.011
transcription initiation from rna polymerase ii promoterGO:0006367250.011
dna packagingGO:0006323910.011
single organism catabolic processGO:00447122280.011
regulation of defense responseGO:00313471020.010
negative regulation of chromosome segregationGO:0051985140.010
histone mrna 3 end processingGO:000639880.010
purine nucleotide catabolic processGO:00061951090.010
negative regulation of cell differentiationGO:00455961430.010
segmentationGO:00352822070.010
dna conformation changeGO:00711031050.010
oocyte anterior posterior axis specificationGO:0007314720.010
innate immune responseGO:00450871440.010
positive regulation of phosphorus metabolic processGO:00105621390.010
regulation of intracellular transportGO:0032386640.010
positive regulation of protein localization to nucleusGO:1900182210.010
negative regulation of catabolic processGO:0009895360.010
purine ribonucleotide catabolic processGO:00091541090.010

dre4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.034
disease of anatomical entityDOID:700.034
disease of cellular proliferationDOID:1456600.010
cancerDOID:16200.010