Drosophila melanogaster

109 known processes

mbt (Dmel_CG18582)

mushroom bodies tiny

(Aliases: CG18582,Ste20,DmMBT,anon-EST:fe1G7,dPAK2,Dmel\CG18582,STE20,Mbt,DmPAK2,Pak2)

mbt biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
head developmentGO:00603221350.865
imaginal disc derived appendage morphogenesisGO:00351143950.694
mushroom body developmentGO:0016319700.689
regulation of phosphate metabolic processGO:00192202100.624
actin filament based processGO:00300292200.617
phosphorylationGO:00163102940.551
actin filament organizationGO:00070151260.542
eye developmentGO:00016543230.527
establishment of localization in cellGO:00516494020.516
regulation of cytoskeleton organizationGO:0051493890.514
single organism cellular localizationGO:19025801800.512
growthGO:00400073590.500
eye photoreceptor cell developmentGO:0042462810.495
guanosine containing compound metabolic processGO:1901068740.449
nucleotide catabolic processGO:00091661090.441
guanosine containing compound catabolic processGO:1901069740.427
response to abiotic stimulusGO:00096283410.425
ribonucleoside catabolic processGO:00424541120.423
purine nucleoside triphosphate catabolic processGO:00091461080.421
nucleobase containing compound catabolic processGO:00346551650.417
regulation of phosphorylationGO:00423251470.414
regulation of actin cytoskeleton organizationGO:0032956420.412
appendage morphogenesisGO:00351073970.394
centrosome organizationGO:00512971630.387
regulation of cellular component sizeGO:0032535980.379
purine ribonucleotide catabolic processGO:00091541090.378
actin cytoskeleton organizationGO:00300362060.378
regulation of cell sizeGO:0008361630.369
purine ribonucleoside catabolic processGO:00461301120.367
signal transduction by phosphorylationGO:00230141070.349
nucleoside triphosphate catabolic processGO:00091431080.337
carbohydrate derivative catabolic processGO:19011361180.336
cellular macromolecule localizationGO:00707272200.331
nucleoside catabolic processGO:00091641120.329
ribose phosphate metabolic processGO:00196931450.326
small gtpase mediated signal transductionGO:0007264880.322
purine ribonucleoside triphosphate catabolic processGO:00092071080.318
photoreceptor cell differentiationGO:00465301700.315
purine ribonucleoside triphosphate metabolic processGO:00092051190.309
regulation of neurogenesisGO:00507671580.303
regulation of small gtpase mediated signal transductionGO:0051056930.303
cell cell signaling involved in cell fate commitmentGO:00451682100.300
regulation of protein metabolic processGO:00512462560.299
regulation of growthGO:00400082330.294
imaginal disc derived appendage developmentGO:00487373990.290
ribonucleoside triphosphate catabolic processGO:00092031080.288
neurological system processGO:00508773580.287
Mouse
ras protein signal transductionGO:0007265880.286
positive regulation of gtp catabolic processGO:0033126430.285
heterocycle catabolic processGO:00467001660.285
aromatic compound catabolic processGO:00194391660.284
negative regulation of response to stimulusGO:00485852580.280
Mouse
cellular protein localizationGO:00346131600.279
purine nucleoside catabolic processGO:00061521120.279
appendage developmentGO:00487364010.268
regulation of developmental growthGO:00486381740.261
nucleobase containing small molecule metabolic processGO:00550861740.256
purine containing compound metabolic processGO:00725211550.256
developmental growthGO:00485892800.255
single organism membrane organizationGO:0044802930.254
regulation of catalytic activityGO:00507901850.253
regulation of photoreceptor cell differentiationGO:0046532340.248
gtp catabolic processGO:0006184720.248
glycosyl compound catabolic processGO:19016581120.243
regulation of intracellular signal transductionGO:19025312360.242
morphogenesis of an epitheliumGO:00020092760.238
post embryonic appendage morphogenesisGO:00351203850.237
purine nucleotide catabolic processGO:00061951090.233
chromosome organizationGO:00512763600.232
nucleoside metabolic processGO:00091161270.232
lateral inhibitionGO:00463312060.228
nucleoside triphosphate metabolic processGO:00091411200.225
negative regulation of cell communicationGO:00106482230.218
Mouse
single organism intracellular transportGO:19025822070.209
regulation of phosphorus metabolic processGO:00511742100.205
organophosphate metabolic processGO:00196371950.197
nucleoside phosphate metabolic processGO:00067531620.193
regulation of catabolic processGO:00098941700.189
positive regulation of phosphorus metabolic processGO:00105621390.188
nucleoside phosphate catabolic processGO:19012921100.187
nucleotide metabolic processGO:00091171610.183
regulation of organelle organizationGO:00330431960.180
positive regulation of phosphate metabolic processGO:00459371390.180
cellular nitrogen compound catabolic processGO:00442701650.179
positive regulation of catalytic activityGO:00430851180.178
purine nucleotide metabolic processGO:00061631460.176
purine ribonucleotide metabolic processGO:00091501450.173
purine ribonucleoside metabolic processGO:00461281270.171
muscle structure developmentGO:00610612240.169
protein localizationGO:00081042840.163
imaginal disc derived wing morphogenesisGO:00074763370.162
organonitrogen compound catabolic processGO:19015651280.159
protein localization to organelleGO:0033365820.159
regulation of cellular component biogenesisGO:00440872010.155
regulation of gtp catabolic processGO:0033124440.153
regulation of anatomical structure sizeGO:00900661630.153
ribonucleoside triphosphate metabolic processGO:00091991190.150
epithelial cell differentiationGO:00308553220.147
positive regulation of gtpase activityGO:0043547430.146
wing disc morphogenesisGO:00074723440.142
regulation of cell differentiationGO:00455953020.139
positive regulation of cellular protein metabolic processGO:00322701180.139
intracellular signal transductionGO:00355563000.139
transcription from rna polymerase ii promoterGO:00063663680.136
ribonucleotide metabolic processGO:00092591450.136
response to woundingGO:0009611940.134
regulation of ras protein signal transductionGO:0046578930.134
purine containing compound catabolic processGO:00725231120.133
protein modification processGO:00362114380.133
regulation of gtpase activityGO:0043087440.133
cellular protein modification processGO:00064644380.131
multicellular organismal agingGO:00102591400.129
positive regulation of hydrolase activityGO:0051345780.126
actin filament bundle assemblyGO:0051017260.126
ribonucleoside metabolic processGO:00091191270.123
regulation of nervous system developmentGO:00519602480.120
tissue morphogenesisGO:00487292970.119
golgi organizationGO:0007030660.116
negative regulation of biosynthetic processGO:00098902770.115
actin filament bundle organizationGO:0061572280.113
organonitrogen compound metabolic processGO:19015643180.109
ribonucleotide catabolic processGO:00092611090.107
intracellular transportGO:00469072280.105
sensory organ morphogenesisGO:00905962600.102
regulation of cellular catabolic processGO:00313291570.101
negative regulation of small gtpase mediated signal transductionGO:0051058130.101
positive regulation of nucleoside metabolic processGO:0045979470.100
positive regulation of response to stimulusGO:00485843230.097
positive regulation of purine nucleotide catabolic processGO:0033123460.096
purine nucleoside triphosphate metabolic processGO:00091441190.096
regulation of ras gtpase activityGO:0032318380.096
gtp metabolic processGO:0046039720.094
glycosyl compound metabolic processGO:19016571270.094
endosomal transportGO:0016197440.094
eye morphogenesisGO:00485922600.088
carbohydrate derivative metabolic processGO:19011352170.087
regionalizationGO:00030024160.087
regulation of nucleoside metabolic processGO:0009118500.084
regulation of cell developmentGO:00602842150.083
embryo development ending in birth or egg hatchingGO:00097921520.083
catabolic processGO:00090564090.083
cell motilityGO:00488702510.083
protein complex disassemblyGO:0043241360.082
regulation of hydrolase activityGO:0051336970.082
regulation of proteolysisGO:0030162870.081
compound eye photoreceptor cell differentiationGO:00017511400.081
negative regulation of cellular metabolic processGO:00313243820.080
vesicle mediated transportGO:00161923810.079
cytoplasmic transportGO:00164821300.079
endomembrane system organizationGO:00102561190.077
regulation of response to stressGO:00801342000.077
positive regulation of signal transductionGO:00099672230.076
negative regulation of signalingGO:00230572190.076
Mouse
learningGO:0007612750.075
Mouse
regulation of nucleotide catabolic processGO:0030811480.074
cell proliferationGO:00082832990.073
macromolecular complex assemblyGO:00650032560.073
central nervous system developmentGO:00074172010.072
positive regulation of endopeptidase activityGO:0010950260.071
regulation of cellular response to stressGO:0080135890.071
regulation of nucleotide metabolic processGO:0006140620.071
positive regulation of nucleotide catabolic processGO:0030813460.070
rho protein signal transductionGO:0007266140.070
negative regulation of multicellular organismal processGO:00512411420.070
establishment of protein localizationGO:00451841630.070
regulation of cellular protein metabolic processGO:00322682430.070
positive regulation of programmed cell deathGO:0043068620.067
forebrain developmentGO:003090020.067
regulation of endopeptidase activityGO:0052548360.066
photoreceptor cell developmentGO:0042461960.065
regulation of purine nucleotide metabolic processGO:1900542620.065
regulation of macroautophagyGO:0016241150.064
stress activated protein kinase signaling cascadeGO:0031098550.063
neuronal stem cell divisionGO:0036445350.063
organic cyclic compound catabolic processGO:19013611680.063
positive regulation of nucleotide metabolic processGO:0045981550.062
enzyme linked receptor protein signaling pathwayGO:00071671790.062
cell divisionGO:00513012480.061
regulation of molecular functionGO:00650092170.060
organophosphate catabolic processGO:00464341120.060
dendrite developmentGO:00163582040.058
cellular response to dna damage stimulusGO:00069742230.058
regulation of cysteine type endopeptidase activityGO:2000116270.056
salivary gland developmentGO:00074311620.053
regulation of neuron differentiationGO:00456641030.052
positive regulation of response to external stimulusGO:0032103440.052
compound eye photoreceptor developmentGO:0042051780.051
immune system processGO:00023763470.051
positive regulation of cell communicationGO:00106472500.051
receptor clusteringGO:004311330.050
negative regulation of organelle organizationGO:0010639560.050
cellularizationGO:0007349900.049
purine nucleoside metabolic processGO:00422781270.048
exocrine system developmentGO:00352721620.048
positive regulation of ras gtpase activityGO:0032320360.048
positive regulation of signalingGO:00230562430.047
proteolysisGO:00065081920.047
negative regulation of cellular component organizationGO:00511291080.047
skin developmentGO:0043588650.047
centrosome cycleGO:00070981370.046
positive regulation of nucleobase containing compound metabolic processGO:00459353320.046
jnk cascadeGO:0007254500.046
negative regulation of nitrogen compound metabolic processGO:00511722650.043
regulation of stress activated mapk cascadeGO:0032872410.043
regulation of anatomical structure morphogenesisGO:00226032420.042
negative regulation of erk1 and erk2 cascadeGO:007037330.042
multicellular organism growthGO:0035264460.042
small molecule metabolic processGO:00442813050.042
cellular component disassemblyGO:0022411460.041
negative regulation of neurogenesisGO:0050768530.041
imaginal disc fusionGO:0046528190.041
regulation of peptidase activityGO:0052547390.041
terminal region determinationGO:0007362250.041
dendrite morphogenesisGO:00488131990.040
spermatid differentiationGO:00485151140.040
negative regulation of nervous system developmentGO:0051961920.039
negative regulation of cellular biosynthetic processGO:00313272770.039
positive regulation of mapk cascadeGO:0043410630.038
single organism catabolic processGO:00447122280.038
regulation of cell deathGO:00109411730.038
Mouse
negative regulation of gene expressionGO:00106293870.037
gland developmentGO:00487321910.037
spermatogenesisGO:00072832000.037
regulation of purine nucleotide catabolic processGO:0033121480.037
cognitionGO:00508901410.037
Mouse
imaginal disc derived wing vein specificationGO:0007474480.036
negative regulation of signal transductionGO:00099682060.036
Mouse
regulation of cell morphogenesisGO:00226041630.034
regulation of apoptotic processGO:00429811300.034
Mouse
negative regulation of intracellular signal transductionGO:1902532570.034
microtubule organizing center organizationGO:00310231680.033
positive regulation of purine nucleotide metabolic processGO:1900544550.033
protein depolymerizationGO:0051261310.033
response to organic substanceGO:00100332840.032
regulation of jnk cascadeGO:0046328400.032
establishment or maintenance of cell polarityGO:00071631670.032
ameboidal type cell migrationGO:00016671510.031
protein transportGO:00150311550.031
cellular catabolic processGO:00442483720.031
negative regulation of cell developmentGO:0010721620.030
stress activated mapk cascadeGO:0051403520.030
regulation of protein complex disassemblyGO:0043244290.030
apoptotic processGO:00069151590.030
Mouse
brain developmentGO:00074201200.030
positive regulation of phosphorylationGO:0042327870.030
compound eye morphogenesisGO:00017452490.029
mitochondrion localizationGO:0051646170.029
negative regulation of nucleic acid templated transcriptionGO:19035072400.028
endocytosisGO:00068973100.028
larval developmentGO:00021641040.028
cellular amine metabolic processGO:0044106120.027
notch receptor processingGO:0007220130.027
regulation of microtubule cytoskeleton organizationGO:0070507410.027
locomotory behaviorGO:00076261760.027
Mouse
positive regulation of multicellular organismal processGO:00512401430.027
protein complex assemblyGO:00064612000.026
cellular response to oxygen containing compoundGO:1901701790.026
organic substance catabolic processGO:19015753080.026
positive regulation of cellular component biogenesisGO:0044089800.026
respiratory system developmentGO:00605412130.025
embryonic morphogenesisGO:00485982060.025
regulation of synapse structure and activityGO:00508031280.025
epidermis developmentGO:0008544650.025
nucleocytoplasmic transportGO:0006913720.025
eye photoreceptor cell differentiationGO:00017541450.024
asymmetric stem cell divisionGO:0098722490.024
regulation of cell shapeGO:00083601130.024
cellular response to chemical stimulusGO:00708871990.024
regulation of multi organism processGO:00439001310.024
membrane organizationGO:00610241120.023
protein complex biogenesisGO:00702712010.023
chromatin assembly or disassemblyGO:0006333520.023
negative regulation of rna metabolic processGO:00512532510.023
positive regulation of cell developmentGO:0010720610.022
neuron projection extensionGO:1990138320.022
defense responseGO:00069523000.022
amine metabolic processGO:0009308120.022
male gamete generationGO:00482322010.022
positive regulation of cell projection organizationGO:0031346290.022
positive regulation of cell sizeGO:0045793210.022
cellular component assembly involved in morphogenesisGO:00109271510.021
regulation of transcription from rna polymerase ii promoterGO:00063573780.021
positive regulation of molecular functionGO:00440931360.021
oocyte developmentGO:00485991240.021
centrosome duplicationGO:00512981210.021
oocyte maturationGO:000155630.021
regulation of locomotionGO:0040012420.021
negative regulation of photoreceptor cell differentiationGO:004653380.021
oocyte differentiationGO:00099941450.021
negative regulation of notch signaling pathwayGO:0045746410.020
developmental maturationGO:00217001720.020
regulation of mapk cascadeGO:0043408920.020
regulation of cellular amine metabolic processGO:003323830.020
regulation of cell projection organizationGO:0031344920.020
positive regulation of catabolic processGO:00098961050.020
regulation of nucleocytoplasmic transportGO:0046822350.020
convergent extensionGO:006002620.020
regulation of stress activated protein kinase signaling cascadeGO:0070302420.020
actin polymerization or depolymerizationGO:0008154310.020
ommatidial rotationGO:0016318200.019
cellular response to peptideGO:1901653280.019
negative regulation of erbb signaling pathwayGO:1901185290.019
negative regulation of ras protein signal transductionGO:0046580130.019
establishment of cell polarityGO:0030010400.019
stem cell divisionGO:0017145690.019
regulation of response to nutrient levelsGO:0032107180.019
non sensory hair organizationGO:0035316470.019
deathGO:00162652840.018
Mouse
mapk cascadeGO:00001651070.018
actomyosin structure organizationGO:0031032560.018
establishment of protein localization to organelleGO:0072594620.018
nuclear divisionGO:00002803320.018
meiotic cell cycle processGO:19030461320.017
lipid metabolic processGO:00066291210.017
regulation of notch signaling pathwayGO:00085931000.017
regulation of neuron projection developmentGO:0010975690.017
cell projection assemblyGO:0030031940.017
epithelium migrationGO:00901321480.017
reproductive structure developmentGO:0048608740.017
secondary metabolic processGO:0019748750.017
regulation of protein complex assemblyGO:0043254420.016
protein maturationGO:0051604710.016
cell cycle checkpointGO:0000075950.016
regulation of embryonic developmentGO:0045995680.016
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178650.015
synapse assemblyGO:00074161430.015
negative regulation of catalytic activityGO:0043086420.015
germarium derived egg chamber formationGO:00072931010.015
positive regulation of neurogenesisGO:0050769410.015
negative regulation of cell differentiationGO:00455961430.015
regulation of actin polymerization or depolymerizationGO:0008064270.015
intracellular protein transportGO:00068861040.015
regulation of actin filament based processGO:0032970420.015
regulation of cellular amino acid metabolic processGO:000652100.014
imaginal disc derived wing hair organizationGO:0035317450.014
negative regulation of meiotic cell cycleGO:005144720.014
regulation of organ growthGO:0046620420.014
protein dna complex subunit organizationGO:0071824860.014
sex differentiationGO:0007548810.014
chaeta developmentGO:0022416970.014
negative regulation of developmental processGO:00510932010.014
positive regulation of organelle organizationGO:0010638650.014
muscle adaptationGO:004350010.014
positive regulation of kinase activityGO:0033674250.014
negative regulation of phosphate metabolic processGO:0045936450.014
mitotic nuclear divisionGO:00070672130.014
regulation of axonogenesisGO:0050770320.013
developmental growth involved in morphogenesisGO:0060560650.013
positive regulation of cysteine type endopeptidase activityGO:2001056240.013
establishment of ommatidial planar polarityGO:0042067490.013
nuclear transportGO:0051169720.013
cellular protein complex assemblyGO:0043623710.013
macromolecular complex disassemblyGO:0032984370.013
positive regulation of developmental processGO:00510941430.013
chromatin organizationGO:00063252070.013
phagocytosisGO:00069092150.012
spermatid developmentGO:0007286980.012
negative regulation of macromolecule biosynthetic processGO:00105582700.012
regulation of endocytosisGO:0030100370.012
macroautophagyGO:0016236420.012
negative regulation of cytoskeleton organizationGO:0051494300.012
actin filament polymerizationGO:0030041270.012
mitotic spindle organizationGO:00070522200.012
transposition rna mediatedGO:003219730.012
protein phosphorylationGO:00064681690.012
regulation of transportGO:00510491810.012
epidermal cell differentiationGO:0009913510.012
wound healingGO:0042060750.012
protein localization to membraneGO:0072657190.012
peptidyl amino acid modificationGO:00181931050.012
torso signaling pathwayGO:0008293210.012
organelle fissionGO:00482853400.012
localization of cellGO:00516742570.012
positive regulation of protein phosphorylationGO:0001934340.012
protein localization to nucleusGO:0034504550.011
synaptic transmissionGO:00072682880.011
tube developmentGO:00352952440.011
cortical actin cytoskeleton organizationGO:0030866240.011
synapse organizationGO:00508081960.011
nucleus organizationGO:0006997450.011
embryonic development via the syncytial blastodermGO:00017001480.011
response to temperature stimulusGO:00092661060.011
development of primary sexual characteristicsGO:0045137500.011
positive regulation of cytoskeleton organizationGO:0051495210.011
regulation of immune system processGO:00026821760.011
positive regulation of cellular catabolic processGO:0031331950.011
tube morphogenesisGO:00352391910.011
regulation of mrna metabolic processGO:1903311720.011
regulation of wnt signaling pathwayGO:0030111680.011
response to starvationGO:0042594970.011
positive regulation of protein kinase activityGO:0045860250.011
embryonic axis specificationGO:00005781070.011
regulation of actin filament bundle assemblyGO:003223180.011
protein import into nucleusGO:0006606510.011
mitotic sister chromatid segregationGO:0000070870.011
regulation of transferase activityGO:0051338580.011
positive regulation of cell deathGO:0010942690.011
regulation of localizationGO:00328792750.010
axis specificationGO:00097981670.010
positive regulation of protein metabolic processGO:00512471280.010
protein targeting to nucleusGO:0044744510.010
positive regulation of macromolecule biosynthetic processGO:00105572830.010
response to other organismGO:00517072930.010
positive regulation of cell motilityGO:200014730.010
anterior posterior axis specification embryoGO:00085951030.010
nuclear importGO:0051170510.010

mbt disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.036
disease of mental healthDOID:15000.011
developmental disorder of mental healthDOID:006003700.011