IMP: Integrative Multi-species Prediction

Drosophila melanogaster

6 known processes

CG1887 (Dmel_CG1887)

CG1887 gene product from transcript CG1887-RD

(Aliases: Dmel\CG1887)

Entrez: 38252
FLYBASE: FBgn0035290
UniProtKB: F0JAR1
UniProtKB: A8JNI3
UniProtKB: R9PY22

Process Predictions
Disease Predictions

CG1887 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
anion homeostasis	GO:0055081	3	0.092
response to light stimulus	GO:0009416	124	0.087	Fly
imaginal disc derived appendage development	GO:0048737	399	0.080
single organism biosynthetic process	GO:0044711	206	0.076	Rat Fly
post embryonic appendage morphogenesis	GO:0035120	385	0.072
appendage development	GO:0048736	401	0.063
wing disc morphogenesis	GO:0007472	344	0.063
vesicle mediated transport	GO:0016192	381	0.062	Human Rat Fly
regulation of multicellular organismal development	GO:2000026	414	0.062
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.061
cell cell signaling involved in cell fate commitment	GO:0045168	210	0.060
appendage morphogenesis	GO:0035107	397	0.060
ethanolamine containing compound metabolic process	GO:0042439	4	0.057
cholesterol homeostasis	GO:0042632	3	0.054
regulation of localization	GO:0032879	275	0.053	Human Rat
imaginal disc derived wing morphogenesis	GO:0007476	337	0.053
organic substance transport	GO:0071702	257	0.052	Human Rat Fly
lateral inhibition	GO:0046331	206	0.051
neutral lipid biosynthetic process	GO:0046460	2	0.048
response to abiotic stimulus	GO:0009628	341	0.047	Fly
cellular response to chemical stimulus	GO:0070887	199	0.047	Human
phagocytosis	GO:0006909	215	0.046	Human Rat Fly
positive regulation of lipid storage	GO:0010884	4	0.046	Human
organic substance catabolic process	GO:1901575	308	0.045
organonitrogen compound metabolic process	GO:1901564	318	0.045
sulfur compound metabolic process	GO:0006790	59	0.044
acylglycerol catabolic process	GO:0046464	3	0.044
proteoglycan metabolic process	GO:0006029	10	0.043
endocytosis	GO:0006897	310	0.043	Human Rat Fly
cellular lipid metabolic process	GO:0044255	83	0.043	Fly
oxoacid metabolic process	GO:0043436	103	0.043
cell adhesion	GO:0007155	136	0.042
response to organic substance	GO:0010033	284	0.041	Human
meiotic cell cycle	GO:0051321	171	0.041
sterol homeostasis	GO:0055092	4	0.041
carbohydrate derivative metabolic process	GO:1901135	217	0.040
triglyceride biosynthetic process	GO:0019432	2	0.039
meiotic nuclear division	GO:0007126	151	0.038
carbohydrate derivative biosynthetic process	GO:1901137	85	0.038
macromolecular complex assembly	GO:0065003	256	0.037
g protein coupled receptor signaling pathway	GO:0007186	136	0.037
open tracheal system development	GO:0007424	204	0.037
single organism catabolic process	GO:0044712	228	0.037
positive regulation of response to stimulus	GO:0048584	323	0.036	Human
homeostatic process	GO:0042592	199	0.035
transcription from rna polymerase ii promoter	GO:0006366	368	0.035
catabolic process	GO:0009056	409	0.034
nuclear division	GO:0000280	332	0.034
small molecule metabolic process	GO:0044281	305	0.034
developmental growth	GO:0048589	280	0.033
neutral lipid catabolic process	GO:0046461	3	0.032
regulation of cell differentiation	GO:0045595	302	0.032
defense response	GO:0006952	300	0.031
triglyceride catabolic process	GO:0019433	3	0.031
cellular response to organic substance	GO:0071310	132	0.031	Human
cholesterol transport	GO:0030301	2	0.031	Human
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.030
intracellular signal transduction	GO:0035556	300	0.030
protein complex biogenesis	GO:0070271	201	0.030
cellular catabolic process	GO:0044248	372	0.030
positive regulation of cell communication	GO:0010647	250	0.030
amine metabolic process	GO:0009308	12	0.029
carboxylic acid metabolic process	GO:0019752	92	0.029
phospholipid homeostasis	GO:0055091	1	0.029
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.027
negative regulation of rna metabolic process	GO:0051253	251	0.026
defense response to other organism	GO:0098542	225	0.026
organic acid metabolic process	GO:0006082	103	0.026
taxis	GO:0042330	304	0.026	Fly
organelle fission	GO:0048285	340	0.026
positive regulation of signal transduction	GO:0009967	223	0.026
protein modification process	GO:0036211	438	0.026
response to temperature stimulus	GO:0009266	106	0.026	Fly
protein complex assembly	GO:0006461	200	0.026
organophosphate metabolic process	GO:0019637	195	0.026
epithelial cell differentiation	GO:0030855	322	0.025
compound eye development	GO:0048749	307	0.025
regulation of lipid storage	GO:0010883	22	0.025	Human
rhythmic process	GO:0048511	106	0.025
localization of cell	GO:0051674	257	0.024
positive regulation of macromolecule metabolic process	GO:0010604	405	0.024
respiratory system development	GO:0060541	213	0.024
single organism behavior	GO:0044708	391	0.024
lipid localization	GO:0010876	54	0.024	Human Rat Fly
positive regulation of multicellular organismal process	GO:0051240	143	0.024
glycerolipid catabolic process	GO:0046503	3	0.024
proteoglycan biosynthetic process	GO:0030166	10	0.023
olfactory behavior	GO:0042048	97	0.023
regulation of anatomical structure morphogenesis	GO:0022603	242	0.023
meiosis i	GO:0007127	59	0.023
positive regulation of signaling	GO:0023056	243	0.023
regulation of anatomical structure size	GO:0090066	163	0.023
response to oxygen containing compound	GO:1901700	200	0.022	Human
regulation of lipid transport	GO:0032368	3	0.022
cellular amine metabolic process	GO:0044106	12	0.022
negative regulation of biosynthetic process	GO:0009890	277	0.022
cell proliferation	GO:0008283	299	0.022
positive regulation of gene expression	GO:0010628	290	0.022
phosphatidylethanolamine metabolic process	GO:0046337	1	0.022
response to organophosphorus	GO:0046683	2	0.022
defense response to bacterium	GO:0042742	178	0.022
response to copper ion	GO:0046688	4	0.022
positive regulation of transport	GO:0051050	92	0.022
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.022
growth	GO:0040007	359	0.021
cell motility	GO:0048870	251	0.021
body morphogenesis	GO:0010171	2	0.021
negative regulation of cellular biosynthetic process	GO:0031327	277	0.021
regulation of sequestering of triglyceride	GO:0010889	3	0.021
cellular amino acid metabolic process	GO:0006520	61	0.021
regionalization	GO:0003002	416	0.021
jak stat cascade	GO:0007259	49	0.021
cellular macromolecule localization	GO:0070727	220	0.021
axon development	GO:0061564	297	0.021
organic hydroxy compound metabolic process	GO:1901615	83	0.021
cell migration	GO:0016477	238	0.020
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.020
glycoprotein metabolic process	GO:0009100	41	0.020
pigmentation	GO:0043473	75	0.020	Fly
establishment of localization in cell	GO:0051649	402	0.020
maintenance of location	GO:0051235	73	0.020	Human
positive regulation of cellular biosynthetic process	GO:0031328	316	0.020
actin cytoskeleton organization	GO:0030036	206	0.020
organonitrogen compound catabolic process	GO:1901565	128	0.020
compound eye morphogenesis	GO:0001745	249	0.019
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.019
regulation of sterol transport	GO:0032371	1	0.019
single organism cellular localization	GO:1902580	180	0.019
determination of adult lifespan	GO:0008340	137	0.019
male meiosis	GO:0007140	52	0.019
chemotaxis	GO:0006935	249	0.019
sensory organ morphogenesis	GO:0090596	260	0.019
glycoprotein biosynthetic process	GO:0009101	41	0.019
aging	GO:0007568	143	0.019
eye morphogenesis	GO:0048592	260	0.018
regulation of transport	GO:0051049	181	0.018	Rat
cellular ketone metabolic process	GO:0042180	24	0.018
pigment metabolic process	GO:0042440	84	0.018	Fly
response to biotic stimulus	GO:0009607	294	0.018	Human
positive regulation of catalytic activity	GO:0043085	118	0.018	Human
morphogenesis of an epithelium	GO:0002009	276	0.018
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.018
chromosome organization	GO:0051276	360	0.018
columnar cuboidal epithelial cell development	GO:0002066	249	0.018
protein localization	GO:0008104	284	0.018
chemosensory behavior	GO:0007635	106	0.018
chemical homeostasis	GO:0048878	92	0.017
cellular response to abiotic stimulus	GO:0071214	58	0.017	Fly
negative regulation of cellular metabolic process	GO:0031324	382	0.017
eye photoreceptor cell differentiation	GO:0001754	145	0.017
ribonucleoside metabolic process	GO:0009119	127	0.017
phosphatidic acid metabolic process	GO:0046473	1	0.017
positive regulation of biosynthetic process	GO:0009891	316	0.017
immune response	GO:0006955	246	0.017
regulation of cellular component biogenesis	GO:0044087	201	0.017
response to alcohol	GO:0097305	95	0.017
epithelial cell migration	GO:0010631	148	0.017
regulation of intracellular signal transduction	GO:1902531	236	0.017
tissue migration	GO:0090130	155	0.017
cell death	GO:0008219	279	0.017	Fly
lipid metabolic process	GO:0006629	121	0.017	Rat Fly
photoreceptor cell differentiation	GO:0046530	170	0.016
positive regulation of intracellular signal transduction	GO:1902533	116	0.016
glycosyl compound metabolic process	GO:1901657	127	0.016
regulation of cellular ketone metabolic process	GO:0010565	3	0.016
organophosphate catabolic process	GO:0046434	112	0.016
acylglycerol biosynthetic process	GO:0046463	2	0.016
compound eye photoreceptor cell differentiation	GO:0001751	140	0.016
death	GO:0016265	284	0.016	Fly
heparan sulfate proteoglycan biosynthetic process	GO:0015012	10	0.016
connective tissue development	GO:0061448	3	0.016
meiotic cell cycle process	GO:1903046	132	0.016
eye pigment metabolic process	GO:0042441	33	0.016	Fly
negative regulation of transcription dna templated	GO:0045892	237	0.016
cellular protein modification process	GO:0006464	438	0.016
embryonic pattern specification	GO:0009880	174	0.015
response to external biotic stimulus	GO:0043207	293	0.015	Human
alditol phosphate metabolic process	GO:0052646	2	0.015
germ cell migration	GO:0008354	43	0.015
response to other organism	GO:0051707	293	0.015	Human
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.015
heparan sulfate proteoglycan metabolic process	GO:0030201	10	0.015
intracellular transport	GO:0046907	228	0.015
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.015
regulation of catalytic activity	GO:0050790	185	0.015	Human
protein transport	GO:0015031	155	0.015
nucleoside phosphate metabolic process	GO:0006753	162	0.015
columnar cuboidal epithelial cell differentiation	GO:0002065	256	0.015
regulation of molecular function	GO:0065009	217	0.015	Human
mitotic nuclear division	GO:0007067	213	0.015
purine containing compound metabolic process	GO:0072521	155	0.015
regulation of cholesterol transport	GO:0032374	1	0.015
positive regulation of molecular function	GO:0044093	136	0.015	Human
cellular response to radiation	GO:0071478	52	0.015	Fly
ion transport	GO:0006811	145	0.015
positive regulation of phosphorus metabolic process	GO:0010562	139	0.015
negative regulation of rna biosynthetic process	GO:1902679	240	0.014
response to nitrogen compound	GO:1901698	90	0.014
cell division	GO:0051301	248	0.014
digestive system development	GO:0055123	149	0.014
regulation of cellular catabolic process	GO:0031329	157	0.014
response to bacterium	GO:0009617	198	0.014	Human
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.014
small molecule biosynthetic process	GO:0044283	37	0.014
cation transport	GO:0006812	110	0.014
regulation of phosphorus metabolic process	GO:0051174	210	0.014
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.014
biological adhesion	GO:0022610	138	0.014	Human
cellular protein localization	GO:0034613	160	0.014
regulation of phosphate metabolic process	GO:0019220	210	0.014
cellular modified amino acid metabolic process	GO:0006575	45	0.014
regulation of immune system process	GO:0002682	176	0.014	Human
regulation of growth	GO:0040008	233	0.014
positive regulation of rna metabolic process	GO:0051254	271	0.014
regulation of cellular protein metabolic process	GO:0032268	243	0.013
triglyceride metabolic process	GO:0006641	12	0.013
tube development	GO:0035295	244	0.013
lipid biosynthetic process	GO:0008610	46	0.013	Rat
gland development	GO:0048732	191	0.013	Fly
detection of external stimulus	GO:0009581	66	0.013	Fly
histolysis	GO:0007559	102	0.013	Fly
compound eye photoreceptor development	GO:0042051	78	0.013
ameboidal type cell migration	GO:0001667	151	0.013
eye development	GO:0001654	323	0.013
acylglycerol metabolic process	GO:0006639	12	0.013
detection of stimulus	GO:0051606	156	0.013	Human Fly
single organism intracellular transport	GO:1902582	207	0.013
chromosome segregation	GO:0007059	157	0.013
regulation of developmental growth	GO:0048638	174	0.013
lipid homeostasis	GO:0055088	33	0.013
endomembrane system organization	GO:0010256	119	0.013
regulation of cell cycle	GO:0051726	291	0.013
cellular response to endogenous stimulus	GO:0071495	80	0.013
regulation of cell development	GO:0060284	215	0.013
axon guidance	GO:0007411	233	0.013
carbohydrate derivative catabolic process	GO:1901136	118	0.013
regulation of tube architecture open tracheal system	GO:0035152	68	0.013
nucleobase containing small molecule metabolic process	GO:0055086	174	0.013
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	116	0.013
embryonic development via the syncytial blastoderm	GO:0001700	148	0.013
purine ribonucleoside metabolic process	GO:0046128	127	0.013
response to extracellular stimulus	GO:0009991	116	0.013
embryonic axis specification	GO:0000578	107	0.013
cellular response to biotic stimulus	GO:0071216	4	0.013	Human
response to radiation	GO:0009314	155	0.013	Fly
positive regulation of transcription dna templated	GO:0045893	266	0.013
phosphorylation	GO:0016310	294	0.012
segmentation	GO:0035282	207	0.012
kidney development	GO:0001822	3	0.012
triglyceride homeostasis	GO:0070328	18	0.012
embryo development ending in birth or egg hatching	GO:0009792	152	0.012
neurological system process	GO:0050877	358	0.012
response to endogenous stimulus	GO:0009719	119	0.012
purine nucleotide metabolic process	GO:0006163	146	0.012
epithelial cell development	GO:0002064	274	0.012
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.012
single organism membrane organization	GO:0044802	93	0.012
pigment metabolic process involved in pigmentation	GO:0043474	33	0.012	Fly
tube morphogenesis	GO:0035239	191	0.012
disaccharide transport	GO:0015766	2	0.012
ovarian follicle cell development	GO:0030707	248	0.012
spindle organization	GO:0007051	253	0.012
phosphatidylcholine metabolic process	GO:0046470	3	0.012
actin filament based process	GO:0030029	220	0.012
cell cell adhesion	GO:0098609	26	0.012
purine nucleoside metabolic process	GO:0042278	127	0.012
cellular response to light stimulus	GO:0071482	37	0.012	Fly
establishment of protein localization	GO:0045184	163	0.012
apoptotic process	GO:0006915	159	0.012	Fly
proteolysis	GO:0006508	192	0.012
ommochrome biosynthetic process	GO:0006727	19	0.012
response to calcium ion	GO:0051592	1	0.012
ribonucleotide metabolic process	GO:0009259	145	0.012
rna processing	GO:0006396	147	0.012
ribose phosphate metabolic process	GO:0019693	145	0.012
developmental pigmentation	GO:0048066	68	0.012	Fly
regulation of immune response	GO:0050776	118	0.012	Human
nucleoside catabolic process	GO:0009164	112	0.012
axis specification	GO:0009798	167	0.012
organonitrogen compound biosynthetic process	GO:1901566	117	0.012
oocyte development	GO:0048599	124	0.012
cell maturation	GO:0048469	144	0.012
membrane organization	GO:0061024	112	0.012
developmental maturation	GO:0021700	172	0.012
regulation of protein metabolic process	GO:0051246	256	0.011
rna localization	GO:0006403	115	0.011
regulation of catabolic process	GO:0009894	170	0.011
axonogenesis	GO:0007409	290	0.011
adult behavior	GO:0030534	137	0.011
negative regulation of developmental process	GO:0051093	201	0.011
circadian rhythm	GO:0007623	105	0.011
exocrine system development	GO:0035272	162	0.011	Fly
regulation of nervous system development	GO:0051960	248	0.011
vitamin metabolic process	GO:0006766	2	0.011
response to nutrient levels	GO:0031667	114	0.011
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.011
neuron projection guidance	GO:0097485	241	0.011
cellular homeostasis	GO:0019725	80	0.011
regulation of organelle organization	GO:0033043	196	0.011
ras protein signal transduction	GO:0007265	88	0.011
nucleotide metabolic process	GO:0009117	161	0.011
blastoderm segmentation	GO:0007350	159	0.011
pigment biosynthetic process	GO:0046148	36	0.011	Fly
neutral lipid metabolic process	GO:0006638	12	0.011
purine nucleoside triphosphate metabolic process	GO:0009144	119	0.011
notch signaling pathway	GO:0007219	120	0.011
regulation of response to stress	GO:0080134	200	0.011	Human
positive regulation of phosphate metabolic process	GO:0045937	139	0.010
multi organism behavior	GO:0051705	175	0.010
regulation of cellular amine metabolic process	GO:0033238	3	0.010
gene silencing	GO:0016458	138	0.010
lipid catabolic process	GO:0016042	21	0.010
epithelium migration	GO:0090132	148	0.010
response to organic cyclic compound	GO:0014070	89	0.010
tissue morphogenesis	GO:0048729	297	0.010
forebrain development	GO:0030900	2	0.010
salivary gland development	GO:0007431	162	0.010	Fly
immune response regulating signaling pathway	GO:0002764	2	0.010	Human
sulfur compound biosynthetic process	GO:0044272	16	0.010
positive regulation of cell motility	GO:2000147	3	0.010
cellular response to lipopolysaccharide	GO:0071222	3	0.010	Human
intracellular protein transport	GO:0006886	104	0.010
tripartite regional subdivision	GO:0007351	103	0.010
organic cyclic compound catabolic process	GO:1901361	168	0.010
nucleoside metabolic process	GO:0009116	127	0.010

CG1887 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
lipid metabolism disorder	DOID:3146	0.116
inherited metabolic disorder	DOID:655	0.116
familial combined hyperlipidemia	DOID:13809	0.116
disease of metabolism	DOID:0014667	0.116
familial hyperlipidemia	DOID:1168	0.116
disease of anatomical entity	DOID:7	0.065
familial hypertriglyceridemia	DOID:0050527	0.046
acquired metabolic disease	DOID:0060158	0.034
diabetes mellitus	DOID:9351	0.034
carbohydrate metabolism disease	DOID:0050013	0.034
glucose metabolism disease	DOID:4194	0.034
familial lipoprotein lipase deficiency	DOID:14118	0.033
hair disease	DOID:421	0.028
hypotrichosis	DOID:4535	0.028
integumentary system disease	DOID:16	0.028
type 2 diabetes mellitus	DOID:9352	0.023
nervous system disease	DOID:863	0.013

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