Drosophila melanogaster

144 known processes

alpha-Spec (Dmel_CG1977)

alpha Spectrin

(Aliases: l(3)62Bd,dre3,alpha-spectrin,Spec,l(3)dre3,l(3)04276,alfa-Spec,Dmel\CG1977,spectrin,anon-EST:fe2E2,alphaSp,alpha-spec,alpha-Sp,alpha-Spect,alpha,CG1977,alpha-Spc,alpha-Spe,l(3)alpha-Spec,klo,3A9,alphaSpec)

alpha-Spec biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
germarium derived female germ line cyst formationGO:0030727420.965
axon developmentGO:00615642970.943
oocyte differentiationGO:00099941450.930
oocyte developmentGO:00485991240.872
germarium derived egg chamber formationGO:00072931010.863
establishment of localization in cellGO:00516494020.819
synaptic transmissionGO:00072682880.749
organelle localizationGO:00516401480.744
neuromuscular junction developmentGO:00075281490.708
axonogenesisGO:00074092900.707
regulation of multicellular organismal developmentGO:20000264140.692
catabolic processGO:00090564090.640
regulation of synaptic growth at neuromuscular junctionGO:0008582890.615
pole plasm assemblyGO:0007315610.592
female germ line cyst formationGO:0048135420.576
actin filament based processGO:00300292200.573
negative regulation of protein complex disassemblyGO:0043242230.560
establishment of organelle localizationGO:00516561220.557
regulation of cellular component biogenesisGO:00440872010.537
cell proliferationGO:00082832990.506
regulation of synapse organizationGO:00508071100.490
pole plasm oskar mrna localizationGO:0045451460.477
regulation of transcription from rna polymerase ii promoterGO:00063573780.476
establishment or maintenance of cell polarityGO:00071631670.439
regulation of synapse assemblyGO:0051963940.417
oocyte axis specificationGO:00073091080.405
germ line cyst formationGO:0048134440.391
body morphogenesisGO:001017120.385
oocyte anterior posterior axis specificationGO:0007314720.362
sensory organ morphogenesisGO:00905962600.348
regulation of oocyte developmentGO:0060281270.343
microtubule depolymerizationGO:0007019250.339
oocyte constructionGO:00073081120.333
pole plasm mrna localizationGO:0019094490.327
synaptic growth at neuromuscular junctionGO:00511241190.325
membrane organizationGO:00610241120.322
locomotory behaviorGO:00076261760.317
regulation of growthGO:00400082330.312
synaptic vesicle fusion to presynaptic membraneGO:003162970.301
synaptic vesicle recyclingGO:0036465280.296
eye morphogenesisGO:00485922600.295
positive regulation of cellular component organizationGO:00511301560.294
regulation of cell differentiationGO:00455953020.289
growthGO:00400073590.281
regulation of nervous system developmentGO:00519602480.270
synaptic vesicle transportGO:0048489500.263
positive regulation of macromolecule metabolic processGO:00106044050.257
regulation of vesicle mediated transportGO:0060627590.249
developmental growthGO:00485892800.240
organic substance catabolic processGO:19015753080.239
signal releaseGO:0023061490.235
regulation of cytoskeleton organizationGO:0051493890.230
negative regulation of microtubule polymerization or depolymerizationGO:0031111210.229
cellular component disassemblyGO:0022411460.220
mrna metabolic processGO:00160711240.215
negative regulation of cellular metabolic processGO:00313243820.212
regulation of secretion by cellGO:1903530390.206
regulation of cell developmentGO:00602842150.203
compound eye morphogenesisGO:00017452490.203
central nervous system developmentGO:00074172010.196
establishment of vesicle localizationGO:0051650510.190
maintenance of presynaptic active zone structureGO:004879080.190
learning or memoryGO:00076111410.182
vesicle mediated transportGO:00161923810.182
cytoskeleton dependent intracellular transportGO:0030705440.179
negative regulation of cell communicationGO:00106482230.179
positive regulation of biosynthetic processGO:00098913160.175
protein complex disassemblyGO:0043241360.172
regulation of microtubule polymerization or depolymerizationGO:0031110270.170
regulation of organelle organizationGO:00330431960.165
protein modification processGO:00362114380.165
negative regulation of protein depolymerizationGO:1901880230.161
regulation of microtubule cytoskeleton organizationGO:0070507410.152
synapse assemblyGO:00074161430.151
regulation of cellular localizationGO:00603411360.148
macromolecular complex disassemblyGO:0032984370.143
negative regulation of nucleobase containing compound metabolic processGO:00459342610.137
neuron projection guidanceGO:00974852410.136
cellular macromolecular complex assemblyGO:00346221530.134
pole plasm rna localizationGO:0007316520.133
protein depolymerizationGO:0051261310.131
cellular protein complex assemblyGO:0043623710.131
compound eye developmentGO:00487493070.130
regulation of microtubule based processGO:0032886490.123
photoreceptor cell differentiationGO:00465301700.120
single organism intracellular transportGO:19025822070.120
cognitionGO:00508901410.117
vesicle organizationGO:0016050440.113
secretionGO:00469031090.110
nuclear transcribed mrna catabolic process nonsense mediated decayGO:000018480.106
cytoplasm organizationGO:0007028640.105
single organism membrane organizationGO:0044802930.104
posttranscriptional gene silencing by rnaGO:0035194450.103
positive regulation of cellular biosynthetic processGO:00313283160.103
rna localizationGO:00064031150.099
positive regulation of macromolecule biosynthetic processGO:00105572830.098
protein localization to plasma membraneGO:0072659130.098
positive regulation of organelle organizationGO:0010638650.094
morphogenesis of follicular epitheliumGO:0016333360.094
asymmetric protein localizationGO:0008105330.092
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092380.090
epithelial cell developmentGO:00020642740.090
negative regulation of cellular biosynthetic processGO:00313272770.090
associative learningGO:0008306650.090
neurological system processGO:00508773580.087
regulation of gene expression epigeneticGO:00400291280.085
positive regulation of protein metabolic processGO:00512471280.083
single organism cellular localizationGO:19025801800.083
regulation of localizationGO:00328792750.082
heterocycle catabolic processGO:00467001660.081
endoplasmic reticulum organizationGO:0007029130.081
regulation of transportGO:00510491810.080
molting cycleGO:0042303560.079
secretion by cellGO:00329401010.078
negative regulation of gene expressionGO:00106293870.077
multicellular organismal reproductive behaviorGO:00330571100.076
protein modification by small protein conjugationGO:0032446790.076
organonitrogen compound metabolic processGO:19015643180.076
membrane fusionGO:0061025420.075
actin filament polymerizationGO:0030041270.075
positive regulation of axonogenesisGO:005077220.075
intracellular transportGO:00469072280.074
microtubule polymerization or depolymerizationGO:0031109390.073
transcription from rna polymerase ii promoterGO:00063663680.073
notch signaling pathwayGO:00072191200.071
response to biotic stimulusGO:00096072940.071
establishment or maintenance of apical basal cell polarityGO:0035088340.070
regulation of secretionGO:0051046440.069
forebrain developmentGO:003090020.069
small molecule metabolic processGO:00442813050.069
microtubule based transportGO:0010970420.068
regulation of actin filament based processGO:0032970420.068
chemotaxisGO:00069352490.067
ovarian follicle cell developmentGO:00307072480.066
eye developmentGO:00016543230.066
regulation of cell deathGO:00109411730.066
posttranscriptional regulation of gene expressionGO:00106081450.065
regulation of protein complex assemblyGO:0043254420.065
positive regulation of nitrogen compound metabolic processGO:00511733540.064
axon cargo transportGO:0008088290.063
positive regulation of rna metabolic processGO:00512542710.061
positive regulation of secretion by cellGO:1903532200.061
memoryGO:0007613940.061
negative regulation of nervous system developmentGO:0051961920.061
multi organism behaviorGO:00517051750.061
ovipositionGO:0018991190.061
macroautophagyGO:0016236420.060
negative regulation of synaptic growth at neuromuscular junctionGO:0045886390.058
cellular catabolic processGO:00442483720.057
protein ubiquitinationGO:0016567700.056
organic substance transportGO:00717022570.055
organelle assemblyGO:00709251980.052
maternal determination of anterior posterior axis embryoGO:0008358740.052
germarium derived oocyte fate determinationGO:0007294260.051
macromolecular complex assemblyGO:00650032560.051
intracellular mrna localization involved in pattern specification processGO:0060810560.051
nucleus localizationGO:0051647340.051
anterior posterior axis specificationGO:00099481090.051
negative regulation of cellular component organizationGO:00511291080.050
nucleobase containing compound catabolic processGO:00346551650.050
protein localizationGO:00081042840.049
cell divisionGO:00513012480.049
cell maturationGO:00484691440.048
negative regulation of synapse assemblyGO:0051964390.048
actin cytoskeleton organizationGO:00300362060.047
negative regulation of multicellular organismal processGO:00512411420.047
developmental programmed cell deathGO:00106231380.047
single organism membrane fusionGO:0044801420.047
negative regulation of macromolecule biosynthetic processGO:00105582700.047
single organism behaviorGO:00447083910.046
aromatic compound catabolic processGO:00194391660.046
regulation of multi organism processGO:00439001310.046
cation homeostasisGO:0055080510.046
regulation of reproductive processGO:2000241540.045
defense responseGO:00069523000.045
positive regulation of cell projection organizationGO:0031346290.044
tube developmentGO:00352952440.044
positive regulation of cell communicationGO:00106472500.043
protein catabolic processGO:00301631010.043
cellular ion homeostasisGO:0006873390.043
cellular nitrogen compound catabolic processGO:00442701650.043
golgi vesicle transportGO:0048193270.043
negative regulation of epithelial cell proliferationGO:005068040.043
establishment of synaptic vesicle localizationGO:0097480500.042
positive regulation of cellular component biogenesisGO:0044089800.042
oocyte maturationGO:000155630.042
tripartite regional subdivisionGO:00073511030.041
positive regulation of gene expressionGO:00106282900.041
regulation of synaptic transmissionGO:0050804690.041
positive regulation of developmental processGO:00510941430.041
blastoderm segmentationGO:00073501590.040
cytoplasmic transport nurse cell to oocyteGO:0007303120.040
regulation of neurogenesisGO:00507671580.040
negative regulation of developmental processGO:00510932010.039
cellular ketone metabolic processGO:0042180240.039
regulation of microtubule depolymerizationGO:0031114240.038
plasma membrane organizationGO:0007009260.038
positive regulation of transportGO:0051050920.038
macromolecule catabolic processGO:00090571610.038
chromosome segregationGO:00070591570.038
branching involved in open tracheal system developmentGO:0060446450.038
regulation of protein complex disassemblyGO:0043244290.038
organic cyclic compound catabolic processGO:19013611680.037
positive regulation of response to stimulusGO:00485843230.037
positive regulation of nucleic acid templated transcriptionGO:19035082660.037
establishment of protein localization to membraneGO:0090150110.036
regulation of cell proliferationGO:00421271630.036
intracellular mrna localizationGO:0008298660.036
regulation of protein depolymerizationGO:1901879270.036
positive regulation of signalingGO:00230562430.036
spindle localizationGO:0051653220.035
epithelial cell differentiationGO:00308553220.035
actin polymerization or depolymerizationGO:0008154310.034
adult locomotory behaviorGO:0008344760.034
cell recognitionGO:00080371020.034
regulation of erbb signaling pathwayGO:1901184420.033
regulation of mitotic cell cycleGO:00073461900.033
regulation of nurse cell apoptotic processGO:004547790.033
negative regulation of signalingGO:00230572190.032
multi multicellular organism processGO:00447061230.032
synapse organizationGO:00508081960.032
organophosphate catabolic processGO:00464341120.032
positive regulation of cell developmentGO:0010720610.032
phosphorylationGO:00163102940.032
cation transportGO:00068121100.032
response to external biotic stimulusGO:00432072930.031
nitrogen compound transportGO:0071705850.030
camera type eye morphogenesisGO:004859320.030
positive regulation of transcription dna templatedGO:00458932660.029
response to organic substanceGO:00100332840.029
protein complex assemblyGO:00064612000.029
chemosensory behaviorGO:00076351060.028
synaptic vesicle primingGO:001608210.028
positive regulation of nervous system developmentGO:0051962690.028
positive regulation of multicellular organismal processGO:00512401430.028
regulation of notch signaling pathwayGO:00085931000.028
ameboidal type cell migrationGO:00016671510.028
establishment of nucleus localizationGO:0040023260.028
carbohydrate derivative metabolic processGO:19011352170.028
amine metabolic processGO:0009308120.028
regulation of hemocyte proliferationGO:0035206370.027
asymmetric cell divisionGO:0008356370.027
ventral cord developmentGO:0007419160.027
oocyte nucleus localization involved in oocyte dorsal ventral axis specificationGO:0051663120.027
synaptic vesicle endocytosisGO:0048488280.027
cell adhesionGO:00071551360.027
developmental maturationGO:00217001720.027
taxisGO:00423303040.027
negative regulation of response to stimulusGO:00485852580.026
protein complex biogenesisGO:00702712010.026
proteolysis involved in cellular protein catabolic processGO:0051603830.026
regulation of cell maturationGO:1903429270.025
positive regulation of axon guidanceGO:190266910.025
negative regulation of microtubule depolymerizationGO:0007026210.025
cell migrationGO:00164772380.024
neurotransmitter transportGO:0006836370.024
border follicle cell migrationGO:00072981130.024
homeostatic processGO:00425921990.024
mapk cascadeGO:00001651070.023
oocyte dorsal ventral axis specificationGO:0007310340.023
enzyme linked receptor protein signaling pathwayGO:00071671790.023
regulation of response to stressGO:00801342000.023
mitotic nuclear divisionGO:00070672130.023
ribonucleoside metabolic processGO:00091191270.023
positive regulation of nucleobase containing compound metabolic processGO:00459353320.023
negative regulation of notch signaling pathwayGO:0045746410.023
regulation of actin polymerization or depolymerizationGO:0008064270.023
chromosome organizationGO:00512763600.023
substrate adhesion dependent cell spreadingGO:003444620.023
regulation of programmed cell deathGO:00430671520.023
tissue morphogenesisGO:00487292970.022
phosphatidylinositol phosphorylationGO:0046854100.022
regulation of phosphatase activityGO:001092130.022
negative regulation of organelle organizationGO:0010639560.022
regulation of embryonic pattern specificationGO:1902875270.022
microtubule based movementGO:0007018510.022
positive regulation of receptor mediated endocytosisGO:004826070.021
oxoacid metabolic processGO:00434361030.021
meiotic nuclear divisionGO:00071261510.021
cellularizationGO:0007349900.021
vesicle fusionGO:0006906190.021
carboxylic acid metabolic processGO:0019752920.021
gene silencingGO:00164581380.021
regulation of intracellular signal transductionGO:19025312360.020
striated muscle cell differentiationGO:0051146900.020
endocytosisGO:00068973100.020
regulation of epithelial cell proliferationGO:005067840.020
cellular macromolecule localizationGO:00707272200.020
response to reactive oxygen speciesGO:0000302240.020
mrna processingGO:00063971040.020
regulation of cell substrate adhesionGO:001081020.019
regulation of protein polymerizationGO:0032271280.019
symbiosis encompassing mutualism through parasitismGO:0044403160.019
metal ion transportGO:0030001740.019
cellular macromolecule catabolic processGO:00442651360.019
cellular protein modification processGO:00064644380.019
positive regulation of signal transductionGO:00099672230.019
anterior posterior axis specification embryoGO:00085951030.019
neurotransmitter secretionGO:0007269350.019
hindbrain developmentGO:003090220.019
vesicle localizationGO:0051648550.019
spinal cord developmentGO:002151010.019
cytoplasmic transportGO:00164821300.019
single organism catabolic processGO:00447122280.019
organelle fissionGO:00482853400.019
ovarian follicle cell migrationGO:00072971210.018
regulation of endocytosisGO:0030100370.018
photoreceptor cell axon guidanceGO:0072499230.018
endomembrane system organizationGO:00102561190.018
cell cycle g1 s phase transitionGO:0044843310.018
regulation of protein metabolic processGO:00512462560.018
establishment of spindle localizationGO:0051293220.017
establishment or maintenance of bipolar cell polarityGO:0061245340.017
morphogenesis of an epitheliumGO:00020092760.017
response to starvationGO:0042594970.017
long term memoryGO:0007616620.017
epithelium migrationGO:00901321480.016
protein polymerizationGO:0051258420.016
regulation of actin cytoskeleton organizationGO:0032956420.016
negative regulation of rna metabolic processGO:00512532510.016
reproductive behaviorGO:00190981220.016
response to organic cyclic compoundGO:0014070890.016
negative regulation of nucleic acid templated transcriptionGO:19035072400.016
axis specificationGO:00097981670.016
glial cell developmentGO:0021782270.016
protein modification by small protein conjugation or removalGO:00706471060.016
nucleus organizationGO:0006997450.016
establishment of protein localization to plasma membraneGO:009000290.016
cytokinesisGO:0000910900.015
imaginal disc growthGO:0007446370.015
conditioned taste aversionGO:000166130.015
skeletal muscle fiber developmentGO:004874130.015
ribonucleotide metabolic processGO:00092591450.015
tissue migrationGO:00901301550.015
cell deathGO:00082192790.015
axon guidanceGO:00074112330.015
positive regulation of growthGO:0045927750.015
regulation of lamellipodium assemblyGO:0010591150.015
ribonucleoprotein complex subunit organizationGO:0071826280.015
muscle tissue developmentGO:0060537300.014
single organism carbohydrate metabolic processGO:0044723720.014
regulation of system processGO:0044057360.014
regulation of cell projection organizationGO:0031344920.014
cellular homeostasisGO:0019725800.014
establishment of mitochondrion localizationGO:005165470.014
positive regulation of developmental pigmentationGO:004808750.014
positive regulation of cell cycleGO:0045787430.014
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.014
negative regulation of protein metabolic processGO:0051248850.014
embryonic pattern specificationGO:00098801740.014
learningGO:0007612750.014
positive regulation of exocytosisGO:004592140.014
eye antennal disc developmentGO:0035214600.013
negative regulation of biosynthetic processGO:00098902770.013
negative regulation of nitrogen compound metabolic processGO:00511722650.013
negative regulation of cell cycleGO:00457861160.013
membrane buddingGO:000690040.013
meiotic cell cycleGO:00513211710.013
ovarian follicle cell stalk formationGO:0030713170.013
cell cycle arrestGO:000705040.013
sensory perception of chemical stimulusGO:00076061160.013
determination of adult lifespanGO:00083401370.013
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.013
positive regulation of protein localization to plasma membraneGO:190307830.013
negative regulation of hormone biosynthetic processGO:003235310.013
organic hydroxy compound metabolic processGO:1901615830.012
response to oxygen containing compoundGO:19017002000.012
anterior posterior pattern specificationGO:00099521360.012
regulation of mapk cascadeGO:0043408920.012
purine ribonucleoside monophosphate catabolic processGO:0009169380.012
regulation of phosphorus metabolic processGO:00511742100.012
response to lipopolysaccharideGO:003249640.012
brain developmentGO:00074201200.012
nucleobase containing small molecule metabolic processGO:00550861740.012
membrane tubulationGO:009732040.012
establishment or maintenance of polarity of follicular epitheliumGO:0016334260.012
cell cell signaling involved in cell fate commitmentGO:00451682100.012
regulation of cellular ketone metabolic processGO:001056530.012
regulation of neuron deathGO:1901214260.012
cellular response to chemical stimulusGO:00708871990.012
protein transportGO:00150311550.012
cortical actin cytoskeleton organizationGO:0030866240.012
response to alkaloidGO:0043279260.012
larval developmentGO:00021641040.012
cellular amine metabolic processGO:0044106120.012
regulation of translationGO:0006417560.011
muscle organ developmentGO:00075171270.011
carbohydrate metabolic processGO:0005975820.011
regulation of pole plasm oskar mrna localizationGO:0007317270.011
positive regulation of filopodium assemblyGO:0051491150.011
sex differentiationGO:0007548810.011
organic acid metabolic processGO:00060821030.011
positive regulation of mapk cascadeGO:0043410630.011
regulation of cellular amine metabolic processGO:003323830.011
purine nucleotide metabolic processGO:00061631460.011
positive regulation of axon extensionGO:004577320.011
organonitrogen compound biosynthetic processGO:19015661170.011
phagocytosisGO:00069092150.011
negative regulation of mitotic cell cycleGO:00459301090.011
purine nucleoside metabolic processGO:00422781270.011
purine nucleoside monophosphate metabolic processGO:0009126500.011
oocyte microtubule cytoskeleton organizationGO:0016325350.011
regulation of neuron differentiationGO:00456641030.011
rna splicingGO:0008380830.010
response to toxic substanceGO:0009636220.010
positive regulation of neurogenesisGO:0050769410.010
developmental growth involved in morphogenesisGO:0060560650.010
negative regulation of rna biosynthetic processGO:19026792400.010
regulation of developmental growthGO:00486381740.010

alpha-Spec disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.177
cardiovascular system diseaseDOID:128700.055
disease of cellular proliferationDOID:1456600.019
cancerDOID:16200.019
musculoskeletal system diseaseDOID:1700.016
organ system cancerDOID:005068600.012