| cullin deneddylation | GO:0010388 | 3 | 0.978 | Human |
| protein deneddylation | GO:0000338 | 8 | 0.836 | |
| mitotic cell cycle checkpoint | GO:0007093 | 88 | 0.425 | |
| mitotic dna integrity checkpoint | GO:0044774 | 75 | 0.402 | |
| cellular response to dna damage stimulus | GO:0006974 | 223 | 0.358 | |
| mitotic dna damage checkpoint | GO:0044773 | 74 | 0.340 | |
| mitotic g2 dna damage checkpoint | GO:0007095 | 69 | 0.335 | |
| negative regulation of mitotic cell cycle phase transition | GO:1901991 | 103 | 0.320 | |
| mitotic g2 m transition checkpoint | GO:0044818 | 70 | 0.319 | |
| modification dependent macromolecule catabolic process | GO:0043632 | 79 | 0.280 | |
| negative regulation of cell cycle phase transition | GO:1901988 | 103 | 0.272 | |
| g2 dna damage checkpoint | GO:0031572 | 69 | 0.250 | |
| protein modification by small protein removal | GO:0070646 | 28 | 0.244 | |
| negative regulation of cell cycle process | GO:0010948 | 109 | 0.220 | |
| negative regulation of mitotic cell cycle | GO:0045930 | 109 | 0.200 | |
| cellular protein modification process | GO:0006464 | 438 | 0.197 | |
| cell cycle phase transition | GO:0044770 | 140 | 0.185 | |
| positive regulation of nucleobase containing compound metabolic process | GO:0045935 | 332 | 0.179 | |
| protein ubiquitination | GO:0016567 | 70 | 0.159 | |
| cellular catabolic process | GO:0044248 | 372 | 0.141 | |
| protein modification process | GO:0036211 | 438 | 0.137 | |
| mitotic spindle organization | GO:0007052 | 220 | 0.128 | |
| macromolecule catabolic process | GO:0009057 | 161 | 0.126 | |
| regulation of mitotic cell cycle | GO:0007346 | 190 | 0.124 | |
| positive regulation of gene expression | GO:0010628 | 290 | 0.109 | |
| regulation of proteasomal ubiquitin dependent protein catabolic process | GO:0032434 | 37 | 0.104 | |
| protein modification by small protein conjugation or removal | GO:0070647 | 106 | 0.102 | |
| cell cycle checkpoint | GO:0000075 | 95 | 0.097 | |
| modification dependent protein catabolic process | GO:0019941 | 78 | 0.092 | |
| positive regulation of macromolecule biosynthetic process | GO:0010557 | 283 | 0.088 | |
| positive regulation of macromolecule metabolic process | GO:0010604 | 405 | 0.084 | |
| histone modification | GO:0016570 | 106 | 0.083 | |
| catabolic process | GO:0009056 | 409 | 0.081 | |
| organic substance catabolic process | GO:1901575 | 308 | 0.081 | |
| mrna cis splicing via spliceosome | GO:0045292 | 1 | 0.079 | |
| regulation of mitotic cell cycle phase transition | GO:1901990 | 130 | 0.078 | |
| cellular macromolecule catabolic process | GO:0044265 | 136 | 0.078 | |
| posttranscriptional regulation of gene expression | GO:0010608 | 145 | 0.077 | |
| regulation of catabolic process | GO:0009894 | 170 | 0.076 | |
| positive regulation of nucleic acid templated transcription | GO:1903508 | 266 | 0.075 | |
| positive regulation of transcription dna templated | GO:0045893 | 266 | 0.072 | |
| chromosome organization | GO:0051276 | 360 | 0.072 | |
| regulation of protein metabolic process | GO:0051246 | 256 | 0.069 | |
| positive regulation of rna biosynthetic process | GO:1902680 | 266 | 0.068 | |
| chromatin modification | GO:0016568 | 147 | 0.068 | |
| ubiquitin dependent protein catabolic process | GO:0006511 | 78 | 0.063 | |
| positive regulation of cellular biosynthetic process | GO:0031328 | 316 | 0.063 | |
| regulation of cellular catabolic process | GO:0031329 | 157 | 0.062 | |
| dna templated transcriptional preinitiation complex assembly | GO:0070897 | 20 | 0.061 | |
| positive regulation of response to stimulus | GO:0048584 | 323 | 0.060 | |
| cellular protein catabolic process | GO:0044257 | 83 | 0.056 | |
| positive regulation of nitrogen compound metabolic process | GO:0051173 | 354 | 0.055 | |
| negative regulation of gene expression | GO:0010629 | 387 | 0.052 | |
| positive regulation of rna metabolic process | GO:0051254 | 271 | 0.051 | |
| regulation of proteolysis | GO:0030162 | 87 | 0.050 | |
| regulation of transcription from rna polymerase ii promoter | GO:0006357 | 378 | 0.048 | |
| dna damage checkpoint | GO:0000077 | 78 | 0.045 | |
| regulation of cell cycle phase transition | GO:1901987 | 130 | 0.045 | |
| regulation of cell cycle process | GO:0010564 | 181 | 0.044 | |
| proteolysis involved in cellular protein catabolic process | GO:0051603 | 83 | 0.042 | |
| dna templated transcription initiation | GO:0006352 | 25 | 0.042 | |
| proteolysis | GO:0006508 | 192 | 0.039 | |
| negative regulation of rna metabolic process | GO:0051253 | 251 | 0.037 | |
| transcription from rna polymerase ii promoter | GO:0006366 | 368 | 0.037 | |
| cell projection assembly | GO:0030031 | 94 | 0.035 | |
| spindle organization | GO:0007051 | 253 | 0.035 | |
| dna integrity checkpoint | GO:0031570 | 81 | 0.034 | |
| phagocytosis | GO:0006909 | 215 | 0.034 | |
| organonitrogen compound metabolic process | GO:1901564 | 318 | 0.033 | |
| negative regulation of cell proliferation | GO:0008285 | 69 | 0.033 | |
| negative regulation of cell cycle | GO:0045786 | 116 | 0.032 | |
| protein catabolic process | GO:0030163 | 101 | 0.031 | |
| regulation of cellular protein metabolic process | GO:0032268 | 243 | 0.030 | |
| organelle assembly | GO:0070925 | 198 | 0.029 | |
| regulation of cellular component biogenesis | GO:0044087 | 201 | 0.029 | |
| protein modification by small protein conjugation | GO:0032446 | 79 | 0.028 | |
| intraspecies interaction between organisms | GO:0051703 | 4 | 0.026 | |
| positive regulation of transcription from rna polymerase ii promoter | GO:0045944 | 204 | 0.026 | |
| regulation of cellular protein catabolic process | GO:1903362 | 44 | 0.025 | |
| methylation | GO:0032259 | 47 | 0.025 | |
| heterocycle catabolic process | GO:0046700 | 166 | 0.024 | |
| purine ribonucleotide catabolic process | GO:0009154 | 109 | 0.023 | |
| regulation of proteolysis involved in cellular protein catabolic process | GO:1903050 | 44 | 0.023 | |
| enzyme linked receptor protein signaling pathway | GO:0007167 | 179 | 0.023 | |
| establishment of nucleus localization | GO:0040023 | 26 | 0.023 | |
| negative regulation of nucleobase containing compound metabolic process | GO:0045934 | 261 | 0.022 | |
| lateral inhibition | GO:0046331 | 206 | 0.022 | |
| immune response | GO:0006955 | 246 | 0.022 | |
| endocytosis | GO:0006897 | 310 | 0.022 | |
| aromatic compound catabolic process | GO:0019439 | 166 | 0.022 | |
| ribonucleoside triphosphate catabolic process | GO:0009203 | 108 | 0.022 | |
| positive regulation of biosynthetic process | GO:0009891 | 316 | 0.022 | |
| eye photoreceptor cell differentiation | GO:0001754 | 145 | 0.021 | |
| positive regulation of signaling | GO:0023056 | 243 | 0.021 | |
| regulation of localization | GO:0032879 | 275 | 0.020 | |
| chromatin organization | GO:0006325 | 207 | 0.020 | |
| proteasomal protein catabolic process | GO:0010498 | 59 | 0.020 | |
| cellular nitrogen compound catabolic process | GO:0044270 | 165 | 0.020 | |
| negative regulation of cellular catabolic process | GO:0031330 | 34 | 0.020 | |
| negative regulation of nitrogen compound metabolic process | GO:0051172 | 265 | 0.020 | |
| cellular response to chemical stimulus | GO:0070887 | 199 | 0.020 | |
| establishment of oocyte nucleus localization involved in oocyte dorsal ventral axis specification | GO:0030722 | 6 | 0.020 | |
| covalent chromatin modification | GO:0016569 | 106 | 0.020 | |
| glycosyl compound catabolic process | GO:1901658 | 112 | 0.020 | |
| response to heat | GO:0009408 | 63 | 0.019 | |
| proteasome mediated ubiquitin dependent protein catabolic process | GO:0043161 | 54 | 0.019 | |
| rna polymerase ii transcriptional preinitiation complex assembly | GO:0051123 | 20 | 0.019 | |
| protein alkylation | GO:0008213 | 43 | 0.019 | |
| cell division | GO:0051301 | 248 | 0.019 | |
| nucleobase containing compound catabolic process | GO:0034655 | 165 | 0.018 | |
| purine nucleotide metabolic process | GO:0006163 | 146 | 0.018 | |
| regulation of smoothened signaling pathway | GO:0008589 | 28 | 0.018 | |
| smoothened signaling pathway | GO:0007224 | 49 | 0.018 | |
| regulation of hydrolase activity | GO:0051336 | 97 | 0.018 | |
| cytokinesis | GO:0000910 | 90 | 0.018 | |
| sister chromatid segregation | GO:0000819 | 92 | 0.018 | |
| nucleoside metabolic process | GO:0009116 | 127 | 0.017 | |
| single organism catabolic process | GO:0044712 | 228 | 0.017 | |
| negative regulation of cellular biosynthetic process | GO:0031327 | 277 | 0.017 | |
| regulation of molecular function | GO:0065009 | 217 | 0.017 | |
| cytoskeleton dependent cytokinesis | GO:0061640 | 81 | 0.017 | |
| carbohydrate derivative catabolic process | GO:1901136 | 118 | 0.017 | |
| regulation of epidermal growth factor receptor signaling pathway | GO:0042058 | 42 | 0.017 | |
| chromosome segregation | GO:0007059 | 157 | 0.017 | |
| cellular response to heat | GO:0034605 | 24 | 0.017 | |
| microtubule cytoskeleton organization involved in mitosis | GO:1902850 | 52 | 0.016 | |
| cellular macromolecular complex assembly | GO:0034622 | 153 | 0.016 | |
| regulation of erbb signaling pathway | GO:1901184 | 42 | 0.016 | |
| ribonucleoside catabolic process | GO:0042454 | 112 | 0.016 | |
| negative regulation of molecular function | GO:0044092 | 51 | 0.016 | |
| purine containing compound metabolic process | GO:0072521 | 155 | 0.016 | |
| negative regulation of cellular macromolecule biosynthetic process | GO:2000113 | 267 | 0.016 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 85 | 0.015 | |
| purine containing compound catabolic process | GO:0072523 | 112 | 0.015 | |
| positive regulation of signal transduction | GO:0009967 | 223 | 0.015 | |
| regulation of protein stability | GO:0031647 | 43 | 0.015 | |
| regulation of protein modification process | GO:0031399 | 112 | 0.015 | |
| positive regulation of catabolic process | GO:0009896 | 105 | 0.014 | |
| molting cycle | GO:0042303 | 56 | 0.014 | |
| protein neddylation | GO:0045116 | 5 | 0.014 | |
| response to external biotic stimulus | GO:0043207 | 293 | 0.014 | |
| regulation of intracellular signal transduction | GO:1902531 | 236 | 0.014 | |
| centrosome organization | GO:0051297 | 163 | 0.014 | |
| transcription initiation from rna polymerase ii promoter | GO:0006367 | 25 | 0.013 | |
| mitotic cell cycle phase transition | GO:0044772 | 138 | 0.013 | |
| intracellular signal transduction | GO:0035556 | 300 | 0.013 | |
| regulation of phosphorus metabolic process | GO:0051174 | 210 | 0.013 | |
| positive regulation of proteolysis | GO:0045862 | 52 | 0.013 | |
| protein dna complex subunit organization | GO:0071824 | 86 | 0.013 | |
| regulation of dna templated transcription elongation | GO:0032784 | 17 | 0.013 | |
| positive regulation of cell communication | GO:0010647 | 250 | 0.012 | |
| photoreceptor cell differentiation | GO:0046530 | 170 | 0.012 | |
| organelle fission | GO:0048285 | 340 | 0.012 | |
| purine nucleotide catabolic process | GO:0006195 | 109 | 0.012 | |
| immune system process | GO:0002376 | 347 | 0.012 | |
| carbohydrate derivative metabolic process | GO:1901135 | 217 | 0.012 | |
| positive regulation of phosphate metabolic process | GO:0045937 | 139 | 0.012 | |
| negative regulation of transcription dna templated | GO:0045892 | 237 | 0.012 | |
| regulation of protein catabolic process | GO:0042176 | 55 | 0.012 | |
| organonitrogen compound catabolic process | GO:1901565 | 128 | 0.012 | |
| positive regulation of cell motility | GO:2000147 | 3 | 0.012 | |
| positive regulation of cellular component biogenesis | GO:0044089 | 80 | 0.011 | |
| negative regulation of proteolysis involved in cellular protein catabolic process | GO:1903051 | 17 | 0.011 | |
| mrna catabolic process | GO:0006402 | 33 | 0.011 | |
| spinal cord development | GO:0021510 | 1 | 0.011 | |
| regulation of neuroblast proliferation | GO:1902692 | 34 | 0.011 | |
| appendage development | GO:0048736 | 401 | 0.011 | |
| negative regulation of cellular metabolic process | GO:0031324 | 382 | 0.011 | |
| compound eye photoreceptor cell differentiation | GO:0001751 | 140 | 0.011 | |
| nucleoside catabolic process | GO:0009164 | 112 | 0.011 | |
| rna interference | GO:0016246 | 27 | 0.011 | |
| positive regulation of cellular catabolic process | GO:0031331 | 95 | 0.011 | |
| cellular response to organic substance | GO:0071310 | 132 | 0.011 | |
| camera type eye development | GO:0043010 | 4 | 0.010 | |
| negative regulation of macromolecule biosynthetic process | GO:0010558 | 270 | 0.010 | |
| organophosphate catabolic process | GO:0046434 | 112 | 0.010 | |
| histone methylation | GO:0016571 | 40 | 0.010 | |
| regulation of protein modification by small protein conjugation or removal | GO:1903320 | 25 | 0.010 | |
| cilium organization | GO:0044782 | 41 | 0.010 | |
| regulation of cell cycle | GO:0051726 | 291 | 0.010 | |
| ras protein signal transduction | GO:0007265 | 88 | 0.010 | |
| positive regulation of proteasomal ubiquitin dependent protein catabolic process | GO:0032436 | 19 | 0.010 | |
| purine ribonucleotide metabolic process | GO:0009150 | 145 | 0.010 | |
