Drosophila melanogaster

122 known processes

sec8 (Dmel_CG2095)

CG2095 gene product from transcript CG2095-RA

(Aliases: CG2095,Sec8,Sec8p,Dmel\CG2095,dsec8)

sec8 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cytokinetic processGO:0032506270.993
cytoskeleton dependent cytokinesisGO:0061640810.990
meiotic cytokinesisGO:0033206330.975
regulation of protein complex disassemblyGO:0043244290.941
ovarian follicle cell migrationGO:00072971210.927
spermatogenesisGO:00072832000.894
negative regulation of protein depolymerizationGO:1901880230.864
cytokinesisGO:0000910900.836
meiosis ii cytokinesisGO:0007111110.829
nuclear divisionGO:00002803320.825
protein depolymerizationGO:0051261310.818
border follicle cell migrationGO:00072981130.804
meiosis i cytokinesisGO:0007110120.800
synapse organizationGO:00508081960.792
cell divisionGO:00513012480.778
contractile ring contractionGO:0036213120.742
meiosis iiGO:0007135230.741
regulation of protein depolymerizationGO:1901879270.736
spindle organizationGO:00070512530.699
negative regulation of microtubule depolymerizationGO:0007026210.687
spermatid developmentGO:0007286980.671
cellular protein complex disassemblyGO:0043624350.664
spindle stabilizationGO:0043146140.631
cellularizationGO:0007349900.602
organelle fissionGO:00482853400.594
regulation of microtubule depolymerizationGO:0031114240.558
epithelial cell differentiationGO:00308553220.552
regulation of microtubule polymerization or depolymerizationGO:0031110270.504
actin cytoskeleton organizationGO:00300362060.498
male gamete generationGO:00482322010.493
columnar cuboidal epithelial cell developmentGO:00020662490.455
regulation of spindle organizationGO:0090224170.453
actomyosin contractile ring contractionGO:0000916120.412
spermatid differentiationGO:00485151140.379
cellular component disassemblyGO:0022411460.374
regulation of cell cycleGO:00517262910.361
meiotic spindle stabilizationGO:004314780.337
intracellular transportGO:00469072280.332
meiotic cell cycle processGO:19030461320.332
protein complex disassemblyGO:0043241360.324
establishment of localization in cellGO:00516494020.293
negative regulation of microtubule polymerization or depolymerizationGO:0031111210.285
microtubule depolymerizationGO:0007019250.272
cellular macromolecule localizationGO:00707272200.271
regulation of synapse structure and activityGO:00508031280.259
epithelial cell developmentGO:00020642740.249
negative regulation of protein complex disassemblyGO:0043242230.244
meiotic nuclear divisionGO:00071261510.238
negative regulation of cytoskeleton organizationGO:0051494300.236
appendage morphogenesisGO:00351073970.232
cell migrationGO:00164772380.226
regulation of cell cycle processGO:00105641810.225
regulation of organelle organizationGO:00330431960.225
actomyosin structure organizationGO:0031032560.224
regulation of microtubule cytoskeleton organizationGO:0070507410.208
mitotic nuclear divisionGO:00070672130.198
protein complex biogenesisGO:00702712010.196
regulation of mitotic cell cycleGO:00073461900.172
regulation of microtubule based processGO:0032886490.169
anterior posterior axis specification embryoGO:00085951030.163
nucleotide metabolic processGO:00091171610.159
cellular response to heatGO:0034605240.153
sperm individualizationGO:0007291480.152
neuromuscular junction developmentGO:00075281490.149
segmentationGO:00352822070.131
striated muscle cell differentiationGO:0051146900.124
single organism intracellular transportGO:19025822070.123
meiosis iGO:0007127590.121
meiotic spindle organizationGO:0000212360.118
mitotic cell cycle phase transitionGO:00447721380.116
meiotic cell cycleGO:00513211710.116
anterior posterior axis specificationGO:00099481090.115
establishment or maintenance of bipolar cell polarityGO:0061245340.114
regulation of cell cycle phase transitionGO:19019871300.109
actin filament based processGO:00300292200.106
negative regulation of cellular component organizationGO:00511291080.102
synapse assemblyGO:00074161430.094
dendrite morphogenesisGO:00488131990.094
rna splicingGO:0008380830.093
protein localizationGO:00081042840.092
regulation of multicellular organismal developmentGO:20000264140.091
intracellular signal transductionGO:00355563000.087
blastoderm segmentationGO:00073501590.086
muscle cell differentiationGO:00426921030.085
regulation of cell deathGO:00109411730.082
spindle assemblyGO:0051225800.080
axonogenesisGO:00074092900.080
endosomal transportGO:0016197440.080
epithelium migrationGO:00901321480.078
regulation of synapse organizationGO:00508071100.075
positive regulation of cellular biosynthetic processGO:00313283160.074
microtubule polymerization or depolymerizationGO:0031109390.072
epithelial cell migrationGO:00106311480.071
mitotic cytokinesisGO:0000281500.071
macromolecular complex disassemblyGO:0032984370.071
single organism cellular localizationGO:19025801800.070
regulation of mitotic cell cycle phase transitionGO:19019901300.069
ovarian follicle cell developmentGO:00307072480.069
macromolecular complex assemblyGO:00650032560.069
regulation of cytoskeleton organizationGO:0051493890.068
anterior posterior pattern specificationGO:00099521360.065
wing disc morphogenesisGO:00074723440.065
organophosphate metabolic processGO:00196371950.065
small molecule metabolic processGO:00442813050.065
synaptic transmissionGO:00072682880.064
rna splicing via transesterification reactionsGO:0000375730.062
post embryonic appendage morphogenesisGO:00351203850.062
centrosome organizationGO:00512971630.061
organonitrogen compound metabolic processGO:19015643180.061
axon developmentGO:00615642970.059
imaginal disc derived wing morphogenesisGO:00074763370.058
regulation of cellular localizationGO:00603411360.058
determination of adult lifespanGO:00083401370.056
purine ribonucleoside metabolic processGO:00461281270.055
vesicle mediated transportGO:00161923810.054
cellular protein localizationGO:00346131600.054
ribonucleotide metabolic processGO:00092591450.054
purine ribonucleotide catabolic processGO:00091541090.050
synaptic growth at neuromuscular junctionGO:00511241190.047
microtubule organizing center organizationGO:00310231680.047
regulation of transcription from rna polymerase ii promoterGO:00063573780.047
positive regulation of transportGO:0051050920.046
compound eye developmentGO:00487493070.045
nucleobase containing small molecule metabolic processGO:00550861740.045
purine containing compound metabolic processGO:00725211550.044
purine nucleotide metabolic processGO:00061631460.044
imaginal disc derived appendage developmentGO:00487373990.044
regulation of nervous system developmentGO:00519602480.044
regulation of cell divisionGO:0051302720.044
purine nucleoside triphosphate metabolic processGO:00091441190.044
cell maturationGO:00484691440.044
columnar cuboidal epithelial cell differentiationGO:00020652560.043
morphogenesis of an epitheliumGO:00020092760.042
intracellular mrna localizationGO:0008298660.042
regulation of cell shapeGO:00083601130.042
cell motilityGO:00488702510.041
regulation of anatomical structure morphogenesisGO:00226032420.041
head developmentGO:00603221350.041
ameboidal type cell migrationGO:00016671510.041
regulation of synaptic growth at neuromuscular junctionGO:0008582890.041
tripartite regional subdivisionGO:00073511030.040
secretionGO:00469031090.039
negative regulation of organelle organizationGO:0010639560.039
organic substance transportGO:00717022570.039
nucleoside metabolic processGO:00091161270.038
transcription from rna polymerase ii promoterGO:00063663680.038
intracellular mrna localization involved in anterior posterior axis specificationGO:0060811530.037
positive regulation of macromolecule metabolic processGO:00106044050.037
proteolysisGO:00065081920.037
cellular macromolecule catabolic processGO:00442651360.037
ribose phosphate metabolic processGO:00196931450.037
purine ribonucleoside triphosphate metabolic processGO:00092051190.037
nucleoside triphosphate metabolic processGO:00091411200.036
cytoplasmic transport nurse cell to oocyteGO:0007303120.036
brain developmentGO:00074201200.036
forebrain developmentGO:003090020.035
protein maturationGO:0051604710.035
carbohydrate derivative metabolic processGO:19011352170.035
telencephalon developmentGO:002153720.034
embryo development ending in birth or egg hatchingGO:00097921520.034
cellular protein modification processGO:00064644380.034
protein complex assemblyGO:00064612000.034
eye morphogenesisGO:00485922600.033
glycosyl compound metabolic processGO:19016571270.033
intracellular protein transportGO:00068861040.033
embryonic axis specificationGO:00005781070.033
tissue migrationGO:00901301550.033
establishment of protein localizationGO:00451841630.032
oocyte axis specificationGO:00073091080.032
axis specificationGO:00097981670.031
embryonic development via the syncytial blastodermGO:00017001480.030
tissue morphogenesisGO:00487292970.030
purine ribonucleotide metabolic processGO:00091501450.030
organelle assemblyGO:00709251980.030
nucleoside phosphate metabolic processGO:00067531620.030
maternal determination of anterior posterior axis embryoGO:0008358740.030
cytoplasmic transportGO:00164821300.029
developmental maturationGO:00217001720.029
regulation of catabolic processGO:00098941700.029
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.029
regulation of cell morphogenesisGO:00226041630.029
protein catabolic processGO:00301631010.029
growthGO:00400073590.028
Worm
oocyte developmentGO:00485991240.028
pole plasm rna localizationGO:0007316520.028
protein processingGO:0016485680.028
neurotransmitter transportGO:0006836370.027
rna localizationGO:00064031150.027
plasma membrane organizationGO:0007009260.027
chromatin assembly or disassemblyGO:0006333520.027
purine ribonucleoside catabolic processGO:00461301120.027
muscle structure developmentGO:00610612240.026
positive regulation of nitrogen compound metabolic processGO:00511733540.026
positive regulation of nucleic acid templated transcriptionGO:19035082660.026
actomyosin contractile ring organizationGO:0044837100.026
establishment or maintenance of apical basal cell polarityGO:0035088340.026
rna processingGO:00063961470.026
positive regulation of nucleobase containing compound metabolic processGO:00459353320.026
guanosine containing compound catabolic processGO:1901069740.026
embryonic pattern specificationGO:00098801740.025
localization of cellGO:00516742570.025
endocytic recyclingGO:0032456130.024
regulation of catalytic activityGO:00507901850.024
actomyosin contractile ring assemblyGO:0000915100.024
heterocycle catabolic processGO:00467001660.024
regulation of behaviorGO:0050795750.024
male meiosis cytokinesisGO:0007112260.024
cell cycle checkpointGO:0000075950.024
regulation of nuclear divisionGO:0051783580.024
regulation of programmed cell deathGO:00430671520.022
regulation of cell developmentGO:00602842150.022
assembly of actomyosin apparatus involved in cytokinesisGO:0000912110.022
protein import into nucleusGO:0006606510.022
gtp catabolic processGO:0006184720.022
ribonucleoside triphosphate metabolic processGO:00091991190.022
cellular component assembly involved in morphogenesisGO:00109271510.021
organic substance catabolic processGO:19015753080.021
neuron recognitionGO:00080381010.021
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281250.021
dendrite developmentGO:00163582040.021
positive regulation of macromolecule biosynthetic processGO:00105572830.021
cellular lipid metabolic processGO:0044255830.021
regulation of transportGO:00510491810.020
oocyte constructionGO:00073081120.020
cytoplasm organizationGO:0007028640.020
neurotransmitter secretionGO:0007269350.020
eggshell formationGO:00307031050.020
purine containing compound catabolic processGO:00725231120.020
positive regulation of rna metabolic processGO:00512542710.020
regulation of cellular component biogenesisGO:00440872010.019
catabolic processGO:00090564090.019
nucleoside catabolic processGO:00091641120.019
purine nucleotide catabolic processGO:00061951090.019
endomembrane system organizationGO:00102561190.019
positive regulation of transcription dna templatedGO:00458932660.018
spermatocyte divisionGO:0048137130.018
chorion containing eggshell formationGO:00073041050.018
regulation of localizationGO:00328792750.018
regulation of nucleoside metabolic processGO:0009118500.018
oocyte anterior posterior axis specificationGO:0007314720.018
regulation of cellular protein metabolic processGO:00322682430.018
regulation of phosphatase activityGO:001092130.018
purine nucleoside metabolic processGO:00422781270.018
nucleocytoplasmic transportGO:0006913720.018
intracellular mrna localization involved in pattern specification processGO:0060810560.018
cellular catabolic processGO:00442483720.017
ribonucleoside metabolic processGO:00091191270.017
cell type specific apoptotic processGO:0097285380.017
positive regulation of endopeptidase activityGO:0010950260.017
regulation of intracellular signal transductionGO:19025312360.017
cell cycle phase transitionGO:00447701400.017
regulation of protein metabolic processGO:00512462560.017
axon guidanceGO:00074112330.017
cell recognitionGO:00080371020.017
positive regulation of hydrolase activityGO:0051345780.017
regulation of vesicle mediated transportGO:0060627590.017
mitotic sister chromatid segregationGO:0000070870.017
negative regulation of cell communicationGO:00106482230.016
negative regulation of signalingGO:00230572190.016
regulation of endopeptidase activityGO:0052548360.016
protein modification processGO:00362114380.016
immune responseGO:00069552460.016
guanosine containing compound metabolic processGO:1901068740.016
regulation of cellular catabolic processGO:00313291570.016
regulation of molecular functionGO:00650092170.016
negative regulation of response to stimulusGO:00485852580.015
chromosome segregationGO:00070591570.015
eye developmentGO:00016543230.015
regulation of developmental growthGO:00486381740.015
Worm
appendage developmentGO:00487364010.015
syncytium formation by plasma membrane fusionGO:0000768430.015
positive regulation of catalytic activityGO:00430851180.015
positive regulation of signalingGO:00230562430.015
regulation of secretionGO:0051046440.015
cellular protein catabolic processGO:0044257830.015
gtp metabolic processGO:0046039720.014
endocytosisGO:00068973100.014
regulation of protein localizationGO:0032880760.014
regulation of protein catabolic processGO:0042176550.014
asymmetric protein localizationGO:0008105330.014
deathGO:00162652840.014
protein transportGO:00150311550.014
positive regulation of cysteine type endopeptidase activityGO:2001056240.014
negative regulation of developmental processGO:00510932010.014
regulation of embryonic developmentGO:0045995680.014
muscle cell developmentGO:0055001500.014
cation transportGO:00068121100.014
positive regulation of rna biosynthetic processGO:19026802660.013
regulation of endocytosisGO:0030100370.013
response to other organismGO:00517072930.013
mrna metabolic processGO:00160711240.013
chromosome organizationGO:00512763600.013
ribonucleoside triphosphate catabolic processGO:00092031080.013
regulation of cysteine type endopeptidase activityGO:2000116270.013
modification dependent macromolecule catabolic processGO:0043632790.013
sister chromatid segregationGO:0000819920.013
multicellular organismal agingGO:00102591400.013
regulation of apoptotic processGO:00429811300.013
proteasomal protein catabolic processGO:0010498590.013
regulation of neurotransmitter levelsGO:0001505380.013
photoreceptor cell differentiationGO:00465301700.013
camera type eye developmentGO:004301040.013
negative regulation of catabolic processGO:0009895360.013
rrna processingGO:000636430.012
establishment or maintenance of epithelial cell apical basal polarityGO:0045197240.012
nucleus organizationGO:0006997450.012
morphogenesis of follicular epitheliumGO:0016333360.012
cellular macromolecular complex assemblyGO:00346221530.012
carbohydrate metabolic processGO:0005975820.012
purine nucleoside triphosphate catabolic processGO:00091461080.012
positive regulation of response to stimulusGO:00485843230.012
regulation of synapse assemblyGO:0051963940.012
eye photoreceptor cell developmentGO:0042462810.012
regulation of proteolysisGO:0030162870.012
neuroblast proliferationGO:0007405740.012
response to heatGO:0009408630.012
negative regulation of mitotic cell cycle phase transitionGO:19019911030.012
phagocytosisGO:00069092150.012
spindle assembly involved in mitosisGO:0090307500.012
positive regulation of biosynthetic processGO:00098913160.012
regionalizationGO:00030024160.012
nucleoside phosphate catabolic processGO:19012921100.011
sensory organ morphogenesisGO:00905962600.011
cell deathGO:00082192790.011
membrane organizationGO:00610241120.011
protein localization to membraneGO:0072657190.011
dorsal appendage formationGO:0046843470.011
nucleobase containing compound catabolic processGO:00346551650.011
protein importGO:0017038550.011
cellular response to dna damage stimulusGO:00069742230.011
adult locomotory behaviorGO:0008344760.011
organic cyclic compound catabolic processGO:19013611680.011
pole plasm assemblyGO:0007315610.011
regulation of gtpase activityGO:0043087440.011
positive regulation of organelle organizationGO:0010638650.011
stem cell proliferationGO:0072089880.011
purine ribonucleoside triphosphate catabolic processGO:00092071080.011
central nervous system developmentGO:00074172010.011
establishment or maintenance of cell polarityGO:00071631670.010
regulation of chromosome organizationGO:0033044640.010
embryonic organ developmentGO:0048568500.010
ion transportGO:00068111450.010
striated muscle cell developmentGO:0055002500.010
secretion by cellGO:00329401010.010

sec8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.028
central nervous system diseaseDOID:33100.024
parkinson s diseaseDOID:1433000.024
nervous system diseaseDOID:86300.024
synucleinopathyDOID:005089000.024
neurodegenerative diseaseDOID:128900.024