IMP: Integrative Multi-species Prediction

Drosophila melanogaster

0 known processes

CG2118 (Dmel_CG2118)

CG2118 gene product from transcript CG2118-RB

(Aliases: mcc,Dmel\CG2118,MCC)

Entrez: 43750
FLYBASE: FBgn0039877
UniProtKB: Q9V9T5
UniProtKB: Q8I0S9

Process Predictions
Disease Predictions

CG2118 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
organonitrogen compound metabolic process	GO:1901564	318	0.117
cell motility	GO:0048870	251	0.110
response to organic substance	GO:0010033	284	0.104
single organism catabolic process	GO:0044712	228	0.103
homeostatic process	GO:0042592	199	0.099
small molecule metabolic process	GO:0044281	305	0.086
localization of cell	GO:0051674	257	0.079
response to temperature stimulus	GO:0009266	106	0.078
response to abiotic stimulus	GO:0009628	341	0.075
response to nitrogen compound	GO:1901698	90	0.073
purine ribonucleoside triphosphate catabolic process	GO:0009207	108	0.072
nucleobase containing small molecule metabolic process	GO:0055086	174	0.069
cellular response to arsenic containing substance	GO:0071243	6	0.069
cation transport	GO:0006812	110	0.068
response to heat	GO:0009408	63	0.065
intracellular signal transduction	GO:0035556	300	0.061
regulation of cellular protein metabolic process	GO:0032268	243	0.059
glycosyl compound metabolic process	GO:1901657	127	0.059
cell migration	GO:0016477	238	0.058
oxidation reduction process	GO:0055114	123	0.056
single organism biosynthetic process	GO:0044711	206	0.055
endocytosis	GO:0006897	310	0.054
single organism intracellular transport	GO:1902582	207	0.053
negative regulation of cellular metabolic process	GO:0031324	382	0.050
phosphorylation	GO:0016310	294	0.045
response to oxygen containing compound	GO:1901700	200	0.045
mitochondrion organization	GO:0007005	65	0.044
organic substance catabolic process	GO:1901575	308	0.044
ribonucleotide catabolic process	GO:0009261	109	0.043
nucleobase containing compound catabolic process	GO:0034655	165	0.043
organic substance transport	GO:0071702	257	0.043
protein phosphorylation	GO:0006468	169	0.042
purine nucleoside metabolic process	GO:0042278	127	0.042
detection of stimulus	GO:0051606	156	0.042
nucleoside catabolic process	GO:0009164	112	0.041
organelle fission	GO:0048285	340	0.041
developmental growth	GO:0048589	280	0.040
vesicle mediated transport	GO:0016192	381	0.040
protein modification process	GO:0036211	438	0.040
translation	GO:0006412	69	0.040
nucleoside metabolic process	GO:0009116	127	0.039
purine ribonucleoside metabolic process	GO:0046128	127	0.039
cellular catabolic process	GO:0044248	372	0.039
small molecule catabolic process	GO:0044282	21	0.039
cellular nitrogen compound catabolic process	GO:0044270	165	0.039
catabolic process	GO:0009056	409	0.038
cellular amino acid metabolic process	GO:0006520	61	0.038
purine ribonucleoside catabolic process	GO:0046130	112	0.037
purine containing compound catabolic process	GO:0072523	112	0.037
organonitrogen compound catabolic process	GO:1901565	128	0.037
nucleoside phosphate catabolic process	GO:1901292	110	0.036
ion transport	GO:0006811	145	0.036
ribonucleotide metabolic process	GO:0009259	145	0.036
nucleoside phosphate metabolic process	GO:0006753	162	0.036
positive regulation of response to stimulus	GO:0048584	323	0.036
dna metabolic process	GO:0006259	227	0.035
aromatic compound catabolic process	GO:0019439	166	0.035
phagocytosis	GO:0006909	215	0.035
purine ribonucleoside triphosphate metabolic process	GO:0009205	119	0.035
morphogenesis of an epithelium	GO:0002009	276	0.035
organic cyclic compound catabolic process	GO:1901361	168	0.034
regulation of developmental growth	GO:0048638	174	0.034
carbohydrate derivative catabolic process	GO:1901136	118	0.034
connective tissue development	GO:0061448	3	0.034
cellular lipid metabolic process	GO:0044255	83	0.033
regulation of catabolic process	GO:0009894	170	0.033
purine ribonucleotide metabolic process	GO:0009150	145	0.032
negative regulation of developmental process	GO:0051093	201	0.032
posttranscriptional regulation of gene expression	GO:0010608	145	0.032
ion transmembrane transport	GO:0034220	122	0.032
heterocycle catabolic process	GO:0046700	166	0.030
atp metabolic process	GO:0046034	49	0.030
ribonucleoside catabolic process	GO:0042454	112	0.030
purine containing compound metabolic process	GO:0072521	155	0.030
establishment of localization in cell	GO:0051649	402	0.030
negative regulation of gene expression	GO:0010629	387	0.030
nucleotide metabolic process	GO:0009117	161	0.030
organic acid metabolic process	GO:0006082	103	0.029
purine nucleotide catabolic process	GO:0006195	109	0.029
positive regulation of cellular component organization	GO:0051130	156	0.029
regulation of multicellular organismal development	GO:2000026	414	0.028
regulation of translation	GO:0006417	56	0.028
dna integrity checkpoint	GO:0031570	81	0.028
divalent metal ion transport	GO:0070838	26	0.028
regulation of programmed cell death	GO:0043067	152	0.027
positive regulation of gene expression	GO:0010628	290	0.027
organophosphate catabolic process	GO:0046434	112	0.027
purine nucleoside monophosphate metabolic process	GO:0009126	50	0.027
taxis	GO:0042330	304	0.027
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.027
skeletal muscle fiber development	GO:0048741	3	0.026
wound healing	GO:0042060	75	0.026
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.026
cellular protein localization	GO:0034613	160	0.026
heterochromatin organization	GO:0070828	25	0.026
detection of light stimulus	GO:0009583	58	0.026
regulation of apoptotic process	GO:0042981	130	0.026
glycosyl compound catabolic process	GO:1901658	112	0.026
detection of abiotic stimulus	GO:0009582	66	0.026
cellular response to chemical stimulus	GO:0070887	199	0.025
immune system process	GO:0002376	347	0.025
positive regulation of developmental growth	GO:0048639	62	0.025
positive regulation of cell migration	GO:0030335	2	0.025
organophosphate metabolic process	GO:0019637	195	0.025
immune response	GO:0006955	246	0.025
intracellular protein transport	GO:0006886	104	0.024
purine nucleoside triphosphate catabolic process	GO:0009146	108	0.024
kidney development	GO:0001822	3	0.024
regulation of intracellular signal transduction	GO:1902531	236	0.024
carbohydrate derivative metabolic process	GO:1901135	217	0.024
purine nucleotide metabolic process	GO:0006163	146	0.024
ribose phosphate metabolic process	GO:0019693	145	0.024
regulation of catalytic activity	GO:0050790	185	0.023
ion homeostasis	GO:0050801	55	0.023
cellular response to organic substance	GO:0071310	132	0.023
ribonucleoside monophosphate metabolic process	GO:0009161	51	0.022
molting cycle chitin based cuticle	GO:0007591	56	0.022
cellular macromolecule localization	GO:0070727	220	0.022
detection of external stimulus	GO:0009581	66	0.022
regulation of dna metabolic process	GO:0051052	34	0.022
synaptic transmission	GO:0007268	288	0.022
positive regulation of protein metabolic process	GO:0051247	128	0.022
intracellular transport	GO:0046907	228	0.022
epithelial cell differentiation	GO:0030855	322	0.022
protein localization	GO:0008104	284	0.021
chromosome organization	GO:0051276	360	0.021
positive regulation of catalytic activity	GO:0043085	118	0.021
regulation of protein metabolic process	GO:0051246	256	0.021
ribonucleoside triphosphate metabolic process	GO:0009199	119	0.021
ribonucleoside metabolic process	GO:0009119	127	0.021
neuron recognition	GO:0008038	101	0.021
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.021
metal ion transport	GO:0030001	74	0.021
regulation of cell cycle process	GO:0010564	181	0.021
response to starvation	GO:0042594	97	0.020
aging	GO:0007568	143	0.020
positive regulation of intracellular signal transduction	GO:1902533	116	0.020
regulation of phosphorus metabolic process	GO:0051174	210	0.020
positive regulation of biosynthetic process	GO:0009891	316	0.019
response to glucose	GO:0009749	2	0.019
cellular protein modification process	GO:0006464	438	0.019
protein complex biogenesis	GO:0070271	201	0.019
cellular response to dna damage stimulus	GO:0006974	223	0.019
positive regulation of multicellular organismal process	GO:0051240	143	0.019
response to endoplasmic reticulum stress	GO:0034976	28	0.019
response to lipopolysaccharide	GO:0032496	4	0.019
cellular response to heat	GO:0034605	24	0.019
multicellular organismal aging	GO:0010259	140	0.018
regulation of cuticle pigmentation	GO:0048079	16	0.018
determination of adult lifespan	GO:0008340	137	0.018
positive regulation of reactive oxygen species metabolic process	GO:2000379	0	0.018
positive regulation of cellular catabolic process	GO:0031331	95	0.018
response to organic cyclic compound	GO:0014070	89	0.018
purine nucleoside catabolic process	GO:0006152	112	0.018
cell aging	GO:0007569	2	0.018
response to endogenous stimulus	GO:0009719	119	0.018
negative regulation of rna biosynthetic process	GO:1902679	240	0.018
ribonucleoside monophosphate catabolic process	GO:0009158	39	0.018
regulation of cellular component biogenesis	GO:0044087	201	0.018
positive regulation of growth	GO:0045927	75	0.018
regulation of innate immune response	GO:0045088	71	0.017
regulation of phosphate metabolic process	GO:0019220	210	0.017
establishment of protein localization	GO:0045184	163	0.017
positive regulation of cellular biosynthetic process	GO:0031328	316	0.017
nucleoside triphosphate catabolic process	GO:0009143	108	0.017
cytoplasmic transport	GO:0016482	130	0.017
negative regulation of transcription dna templated	GO:0045892	237	0.017
response to hexose	GO:0009746	3	0.017
response to organophosphorus	GO:0046683	2	0.017
nucleoside triphosphate metabolic process	GO:0009141	120	0.017
nucleoside monophosphate metabolic process	GO:0009123	52	0.017
growth	GO:0040007	359	0.017
response to oxidative stress	GO:0006979	86	0.016
regulation of molecular function	GO:0065009	217	0.016
immune response regulating signaling pathway	GO:0002764	2	0.016
regulation of bmp signaling pathway	GO:0030510	23	0.016
appendage development	GO:0048736	401	0.016
protein transport	GO:0015031	155	0.016
organic acid catabolic process	GO:0016054	16	0.016
glycerolipid catabolic process	GO:0046503	3	0.016
maintenance of location	GO:0051235	73	0.016
monocarboxylic acid transport	GO:0015718	3	0.016
cellular response to cadmium ion	GO:0071276	6	0.015
cellular response to metal ion	GO:0071248	6	0.015
protein complex assembly	GO:0006461	200	0.015
detection of stimulus involved in sensory perception	GO:0050906	92	0.015
purine ribonucleotide catabolic process	GO:0009154	109	0.015
response to radiation	GO:0009314	155	0.015
dna conformation change	GO:0071103	105	0.015
urogenital system development	GO:0001655	72	0.015
response to light stimulus	GO:0009416	124	0.015
positive regulation of phosphate metabolic process	GO:0045937	139	0.015
positive regulation of cellular protein metabolic process	GO:0032270	118	0.015
generation of precursor metabolites and energy	GO:0006091	42	0.015
activation of innate immune response	GO:0002218	4	0.015
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.015
mushroom body development	GO:0016319	70	0.014
cellular response to lipopolysaccharide	GO:0071222	3	0.014
dorsal ventral axis specification	GO:0009950	66	0.014
regulation of response to stress	GO:0080134	200	0.014
nucleoside monophosphate catabolic process	GO:0009125	39	0.014
cellular response to molecule of bacterial origin	GO:0071219	3	0.014
macromolecular complex assembly	GO:0065003	256	0.014
columnar cuboidal epithelial cell differentiation	GO:0002065	256	0.014
jak stat cascade	GO:0007259	49	0.014
membrane organization	GO:0061024	112	0.014
phototransduction	GO:0007602	52	0.014
cellular response to biotic stimulus	GO:0071216	4	0.014
regulation of cellular ketone metabolic process	GO:0010565	3	0.014
oxoacid metabolic process	GO:0043436	103	0.014
response to monosaccharide	GO:0034284	4	0.014
carboxylic acid metabolic process	GO:0019752	92	0.014
synapse organization	GO:0050808	196	0.014
regulation of cellular catabolic process	GO:0031329	157	0.014
open tracheal system development	GO:0007424	204	0.014
protein targeting	GO:0006605	64	0.014
positive regulation of signal transduction	GO:0009967	223	0.014
heart morphogenesis	GO:0003007	32	0.013
purine nucleoside triphosphate metabolic process	GO:0009144	119	0.013
dorsal ventral pattern formation	GO:0009953	133	0.013
ribonucleoside triphosphate catabolic process	GO:0009203	108	0.013
apoptotic process	GO:0006915	159	0.013
nucleotide catabolic process	GO:0009166	109	0.013
phosphatidylethanolamine metabolic process	GO:0046337	1	0.013
phospholipid homeostasis	GO:0055091	1	0.013
calcium ion transport	GO:0006816	24	0.013
nuclear division	GO:0000280	332	0.013
regulation of defense response	GO:0031347	102	0.013
embryonic morphogenesis	GO:0048598	206	0.013
positive regulation of cysteine type endopeptidase activity involved in apoptotic process	GO:0043280	23	0.013
acylglycerol biosynthetic process	GO:0046463	2	0.013
cellular response to inorganic substance	GO:0071241	8	0.013
nuclear import	GO:0051170	51	0.013
lipid localization	GO:0010876	54	0.013
regulation of cellular response to stress	GO:0080135	89	0.012
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.012
fatty acid metabolic process	GO:0006631	20	0.012
ameboidal type cell migration	GO:0001667	151	0.012
embryonic development via the syncytial blastoderm	GO:0001700	148	0.012
cell proliferation	GO:0008283	299	0.012
positive regulation of nervous system development	GO:0051962	69	0.012
positive regulation of immune response	GO:0050778	63	0.012
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.012
positive regulation of programmed cell death	GO:0043068	62	0.012
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	116	0.012
protein import	GO:0017038	55	0.012
programmed cell death	GO:0012501	257	0.012
regulation of cell differentiation	GO:0045595	302	0.012
chemical homeostasis	GO:0048878	92	0.012
macromolecule catabolic process	GO:0009057	161	0.012
positive regulation of phosphorus metabolic process	GO:0010562	139	0.012
regulation of neurogenesis	GO:0050767	158	0.012
kidney epithelium development	GO:0072073	3	0.012
response to inorganic substance	GO:0010035	44	0.012
purine ribonucleoside monophosphate catabolic process	GO:0009169	38	0.011
dna damage checkpoint	GO:0000077	78	0.011
establishment of protein localization to organelle	GO:0072594	62	0.011
response to wounding	GO:0009611	94	0.011
transcription from rna polymerase ii promoter	GO:0006366	368	0.011
nephron tubule development	GO:0072080	3	0.011
single organism membrane organization	GO:0044802	93	0.011
protein localization to organelle	GO:0033365	82	0.011
regulation of purine nucleotide catabolic process	GO:0033121	48	0.011
regulation of intracellular transport	GO:0032386	64	0.011
regulation of nucleoside metabolic process	GO:0009118	50	0.011
proteolysis	GO:0006508	192	0.011
post embryonic appendage morphogenesis	GO:0035120	385	0.011
positive regulation of defense response	GO:0031349	59	0.011
cation transmembrane transport	GO:0098655	88	0.011
regulation of anatomical structure morphogenesis	GO:0022603	242	0.011
purine nucleoside monophosphate catabolic process	GO:0009128	38	0.011
disaccharide metabolic process	GO:0005984	4	0.010
single organism nuclear import	GO:1902593	51	0.010
single organism cellular localization	GO:1902580	180	0.010
male mating behavior	GO:0060179	70	0.010
positive regulation of cell motility	GO:2000147	3	0.010
cellular lipid catabolic process	GO:0044242	16	0.010
dna duplex unwinding	GO:0032508	16	0.010
regulation of cell cycle	GO:0051726	291	0.010
digestive tract development	GO:0048565	149	0.010
cell maturation	GO:0048469	144	0.010
cellularization	GO:0007349	90	0.010
gtp catabolic process	GO:0006184	72	0.010
imaginal disc derived wing morphogenesis	GO:0007476	337	0.010
cuticle development	GO:0042335	86	0.010
forebrain development	GO:0030900	2	0.010
regulation of purine nucleotide metabolic process	GO:1900542	62	0.010
sulfur compound metabolic process	GO:0006790	59	0.010

CG2118 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability	Func Analog Org
disease of anatomical entity	DOID:7	0.024
disease of metabolism	DOID:0014667	0.023	Human
inherited metabolic disorder	DOID:655	0.023	Human
nervous system disease	DOID:863	0.017
central nervous system disease	DOID:331	0.013

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