IMP: Integrative Multi-species Prediction

Drosophila melanogaster

106 known processes

fs(1)h (Dmel_CG2252)

female sterile (1) homeotic

(Aliases: l(1)G0093,fs(1)1456,Fs(1)hL,CG2252,N72,l(1)7Da,fsh,fst(1)h,fs(1)26/26A,Dmel\CG2252,clone 1.81,rnc,fs(1)R10.4,anon-EST:fe1G2,anon-EST:Liang-1.81,fs(1)M16,l(1)G0495,Fs(1)hS)

Entrez: 31722
FLYBASE: FBgn0004656
UniProtKB: M9PGM8
UniProtKB: E1JJJ8
UniProtKB: M9PE02
UniProtKB: P13709
UniProtKB: M9PJC7

Process Predictions
Disease Predictions

fs(1)h biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
protein modification process	GO:0036211	438	0.713	Human Mouse
positive regulation of rna metabolic process	GO:0051254	271	0.701	Human Mouse
protein modification by small protein conjugation	GO:0032446	79	0.683
embryonic morphogenesis	GO:0048598	206	0.616
negative regulation of cellular metabolic process	GO:0031324	382	0.497
cell division	GO:0051301	248	0.480
regulation of response to stress	GO:0080134	200	0.429	Human
phosphorylation	GO:0016310	294	0.422	Human Mouse
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.387	Human Mouse
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.379	Human Worm
regulation of cell differentiation	GO:0045595	302	0.364
regulation of cellular ketone metabolic process	GO:0010565	3	0.348
epithelial cell differentiation	GO:0030855	322	0.347
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.340	Human Mouse
growth	GO:0040007	359	0.324	Mouse
negative regulation of gene expression	GO:0010629	387	0.316
negative regulation of mitotic cell cycle	GO:0045930	109	0.310
regulation of cellular protein metabolic process	GO:0032268	243	0.304	Human
cell cycle checkpoint	GO:0000075	95	0.264	Human
stem cell differentiation	GO:0048863	117	0.262	Worm
embryonic development via the syncytial blastoderm	GO:0001700	148	0.261
cellular protein modification process	GO:0006464	438	0.257	Human Mouse
negative regulation of cellular biosynthetic process	GO:0031327	277	0.239
negative regulation of cell communication	GO:0010648	223	0.238
response to radiation	GO:0009314	155	0.233
long term memory	GO:0007616	62	0.230
small molecule metabolic process	GO:0044281	305	0.219
positive regulation of gene expression	GO:0010628	290	0.216	Human Mouse
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.216	Human
cellular amino acid metabolic process	GO:0006520	61	0.207
eye development	GO:0001654	323	0.193
protein ubiquitination	GO:0016567	70	0.191
tube development	GO:0035295	244	0.191
regionalization	GO:0003002	416	0.177
positive regulation of macromolecule metabolic process	GO:0010604	405	0.176	Human Mouse
epithelium migration	GO:0090132	148	0.162
regulation of phosphorus metabolic process	GO:0051174	210	0.160	Human
organic substance catabolic process	GO:1901575	308	0.156
response to abiotic stimulus	GO:0009628	341	0.156
digestive tract morphogenesis	GO:0048546	127	0.153
covalent chromatin modification	GO:0016569	106	0.151	Mouse
regulation of catalytic activity	GO:0050790	185	0.142
tube morphogenesis	GO:0035239	191	0.142
columnar cuboidal epithelial cell differentiation	GO:0002065	256	0.140
chromosome organization	GO:0051276	360	0.138	Human Mouse
neuroblast fate commitment	GO:0014017	19	0.135	Worm
tissue morphogenesis	GO:0048729	297	0.135
developmental growth	GO:0048589	280	0.133	Mouse
positive regulation of response to stimulus	GO:0048584	323	0.132	Human
regulation of response to external stimulus	GO:0032101	115	0.130	Human
regulation of embryonic development	GO:0045995	68	0.125
cellular ketone metabolic process	GO:0042180	24	0.124
negative regulation of intracellular signal transduction	GO:1902532	57	0.123
regulation of phosphorylation	GO:0042325	147	0.122	Human
regulation of anatomical structure morphogenesis	GO:0022603	242	0.121
intracellular signal transduction	GO:0035556	300	0.120	Human
regulation of defense response	GO:0031347	102	0.116	Human
transcription from rna polymerase ii promoter	GO:0006366	368	0.115	Human Worm
sensory organ morphogenesis	GO:0090596	260	0.114
regulation of cell projection organization	GO:0031344	92	0.113
regulation of nervous system development	GO:0051960	248	0.110
negative regulation of multicellular organismal process	GO:0051241	142	0.109
cellular amine metabolic process	GO:0044106	12	0.108
positive regulation of cell communication	GO:0010647	250	0.106	Human
peptidyl amino acid modification	GO:0018193	105	0.106	Mouse
regulation of localization	GO:0032879	275	0.106
carboxylic acid metabolic process	GO:0019752	92	0.105
positive regulation of rna biosynthetic process	GO:1902680	266	0.104	Human Mouse
immune system process	GO:0002376	347	0.104
camera type eye development	GO:0043010	4	0.103
male gamete generation	GO:0048232	201	0.101	Mouse
eye morphogenesis	GO:0048592	260	0.101
protein modification by small protein conjugation or removal	GO:0070647	106	0.100
negative regulation of developmental process	GO:0051093	201	0.098
regulation of multicellular organismal development	GO:2000026	414	0.098	Worm
hindbrain development	GO:0030902	2	0.097
programmed cell death	GO:0012501	257	0.096
photoreceptor cell differentiation	GO:0046530	170	0.095
regulation of epithelial cell differentiation	GO:0030856	4	0.091
chromatin organization	GO:0006325	207	0.090	Human Mouse
negative regulation of signaling	GO:0023057	219	0.090
positive regulation of transcription dna templated	GO:0045893	266	0.087	Human Mouse
negative regulation of molecular function	GO:0044092	51	0.087
regulation of cellular amine metabolic process	GO:0033238	3	0.087
oxoacid metabolic process	GO:0043436	103	0.086
regulation of immune system process	GO:0002682	176	0.086
regulation of cell cycle process	GO:0010564	181	0.086	Human
dendrite development	GO:0016358	204	0.086
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.085
regulation of wnt signaling pathway	GO:0030111	68	0.084
regulation of cellular response to stress	GO:0080135	89	0.084	Human
learning or memory	GO:0007611	141	0.081
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.081
death	GO:0016265	284	0.080
regulation of notch signaling pathway	GO:0008593	100	0.080
peptidyl tyrosine phosphorylation	GO:0018108	24	0.079
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.076	Human Mouse
cell migration	GO:0016477	238	0.076
amine metabolic process	GO:0009308	12	0.076
embryo development ending in birth or egg hatching	GO:0009792	152	0.075	Mouse Worm
regulation of protein metabolic process	GO:0051246	256	0.074	Human
regulation of organelle organization	GO:0033043	196	0.073
ectodermal placode morphogenesis	GO:0071697	4	0.073
apoptotic process	GO:0006915	159	0.072
regulation of protein modification process	GO:0031399	112	0.072	Human
signal transduction by phosphorylation	GO:0023014	107	0.072
establishment of localization in cell	GO:0051649	402	0.071
positive regulation of signal transduction	GO:0009967	223	0.070	Human
cell adhesion	GO:0007155	136	0.068
cell motility	GO:0048870	251	0.068
establishment or maintenance of microtubule cytoskeleton polarity	GO:0030951	41	0.065
chromosome segregation	GO:0007059	157	0.065	Mouse
morphogenesis of follicular epithelium	GO:0016333	36	0.065
positive regulation of biosynthetic process	GO:0009891	316	0.065	Human Mouse
dna integrity checkpoint	GO:0031570	81	0.064	Human
positive regulation of multicellular organismal process	GO:0051240	143	0.064
negative regulation of cell cycle phase transition	GO:1901988	103	0.063
nuclear division	GO:0000280	332	0.062	Mouse
positive regulation of catalytic activity	GO:0043085	118	0.062
ectodermal placode development	GO:0071696	4	0.062
histone h3 k4 methylation	GO:0051568	16	0.061
cuticle development	GO:0042335	86	0.059
negative regulation of nervous system development	GO:0051961	92	0.059
immune system development	GO:0002520	57	0.058
hematopoietic progenitor cell differentiation	GO:0002244	1	0.058
response to organic substance	GO:0010033	284	0.058
modification dependent macromolecule catabolic process	GO:0043632	79	0.057
regulation of developmental growth	GO:0048638	174	0.056
regulation of cell development	GO:0060284	215	0.056
imaginal disc derived appendage development	GO:0048737	399	0.056
ovarian follicle cell development	GO:0030707	248	0.055
organic acid metabolic process	GO:0006082	103	0.055
cytoplasmic transport nurse cell to oocyte	GO:0007303	12	0.054
biological adhesion	GO:0022610	138	0.054
regulation of cellular amino acid metabolic process	GO:0006521	0	0.052
embryonic hemopoiesis	GO:0035162	26	0.052
cellular macromolecule catabolic process	GO:0044265	136	0.051
regulation of actin filament based process	GO:0032970	42	0.051
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.051	Human Mouse
cell death	GO:0008219	279	0.051
regulation of apoptotic process	GO:0042981	130	0.051
regulation of intracellular signal transduction	GO:1902531	236	0.049	Human
digestive tract development	GO:0048565	149	0.049
mitotic cell cycle phase transition	GO:0044772	138	0.049	Human
response to biotic stimulus	GO:0009607	294	0.048
endocytosis	GO:0006897	310	0.047
histone h4 acetylation	GO:0043967	13	0.047	Mouse
morphogenesis of an epithelium	GO:0002009	276	0.046
compound eye morphogenesis	GO:0001745	249	0.045
regulation of anatomical structure size	GO:0090066	163	0.044
organonitrogen compound metabolic process	GO:1901564	318	0.044
proteolysis	GO:0006508	192	0.044
positive regulation of signaling	GO:0023056	243	0.044	Human
epithelial cell development	GO:0002064	274	0.044
synapse assembly	GO:0007416	143	0.044
regulation of cell morphogenesis	GO:0022604	163	0.043
vesicle mediated transport	GO:0016192	381	0.042
cellular response to chemical stimulus	GO:0070887	199	0.042
protein catabolic process	GO:0030163	101	0.042
histone h4 k16 acetylation	GO:0043984	4	0.042
regulation of cell death	GO:0010941	173	0.041
spermatogenesis	GO:0007283	200	0.041	Mouse
catabolic process	GO:0009056	409	0.040
retina development in camera type eye	GO:0060041	4	0.040
localization of cell	GO:0051674	257	0.040
regulation of mapk cascade	GO:0043408	92	0.039
negative regulation of cellular protein metabolic process	GO:0032269	85	0.039
regulation of multi organism process	GO:0043900	131	0.038
eggshell chorion assembly	GO:0007306	66	0.038
neurological system process	GO:0050877	358	0.038
positive regulation of cellular biosynthetic process	GO:0031328	316	0.038	Human Mouse
dna metabolic process	GO:0006259	227	0.038	Human
negative regulation of phosphorus metabolic process	GO:0010563	45	0.038
columnar cuboidal epithelial cell development	GO:0002066	249	0.037
anterior posterior pattern specification	GO:0009952	136	0.037
mapk cascade	GO:0000165	107	0.037
protein localization to nucleus	GO:0034504	55	0.037
cellular response to hexose stimulus	GO:0071331	1	0.036
protein transport	GO:0015031	155	0.036
signal transduction by p53 class mediator	GO:0072331	6	0.036
response to nutrient levels	GO:0031667	114	0.036
regulation of proteolysis	GO:0030162	87	0.035
regulation of cellular localization	GO:0060341	136	0.035
positive regulation of developmental process	GO:0051094	143	0.035
convergent extension	GO:0060026	2	0.035
nucleobase containing compound catabolic process	GO:0034655	165	0.034
immune response regulating signaling pathway	GO:0002764	2	0.034
regulation of neuron projection development	GO:0010975	69	0.034
chromatin modification	GO:0016568	147	0.034	Human Mouse
spinal cord development	GO:0021510	1	0.034
regulation of dendrite morphogenesis	GO:0048814	28	0.034
camera type eye morphogenesis	GO:0048593	2	0.034
compound eye development	GO:0048749	307	0.034
germarium derived egg chamber formation	GO:0007293	101	0.033
negative regulation of rna metabolic process	GO:0051253	251	0.033
negative regulation of transcription dna templated	GO:0045892	237	0.033
regulation of tube size	GO:0035150	46	0.033
synaptic growth at neuromuscular junction	GO:0051124	119	0.033
regulation of mitotic cell cycle phase transition	GO:1901990	130	0.033	Human
regulation of molecular function	GO:0065009	217	0.033	Mouse
photoreceptor cell development	GO:0042461	96	0.033
cytoplasmic transport	GO:0016482	130	0.033
memory	GO:0007613	94	0.033
appendage morphogenesis	GO:0035107	397	0.033
developmental programmed cell death	GO:0010623	138	0.032
epidermal growth factor receptor signaling pathway	GO:0007173	58	0.031
negative regulation of apoptotic process	GO:0043066	63	0.031
actin filament bundle assembly	GO:0051017	26	0.030
positive regulation of defense response	GO:0031349	59	0.030
notch signaling pathway	GO:0007219	120	0.030
developmental pigmentation	GO:0048066	68	0.030
response to endogenous stimulus	GO:0009719	119	0.029
immune response activating signal transduction	GO:0002757	2	0.029
mitotic nuclear division	GO:0007067	213	0.029
negative regulation of protein metabolic process	GO:0051248	85	0.029
terminal region determination	GO:0007362	25	0.028
negative regulation of signal transduction	GO:0009968	206	0.028
positive regulation of cell death	GO:0010942	69	0.028
intracellular transport	GO:0046907	228	0.028
dna damage checkpoint	GO:0000077	78	0.027	Human
organelle localization	GO:0051640	148	0.027
phagocytosis	GO:0006909	215	0.027
chorion containing eggshell formation	GO:0007304	105	0.027
hematopoietic or lymphoid organ development	GO:0048534	57	0.027
regulation of peptidyl tyrosine phosphorylation	GO:0050730	10	0.026
macromolecule catabolic process	GO:0009057	161	0.026
cuticle pigmentation	GO:0048067	22	0.025
dosage compensation	GO:0007549	16	0.025
positive regulation of cellular amino acid metabolic process	GO:0045764	0	0.025
body morphogenesis	GO:0010171	2	0.025
membrane depolarization	GO:0051899	4	0.025
protein localization	GO:0008104	284	0.025
negative regulation of phosphate metabolic process	GO:0045936	45	0.025
nuclear transport	GO:0051169	72	0.025
response to organonitrogen compound	GO:0010243	75	0.024
negative regulation of cell cycle	GO:0045786	116	0.024	Human
establishment or maintenance of polarity of follicular epithelium	GO:0016334	26	0.024
regulation of hydrolase activity	GO:0051336	97	0.024
spindle organization	GO:0007051	253	0.024
regulation of protein complex assembly	GO:0043254	42	0.024
stem cell fate commitment	GO:0048865	25	0.024	Worm
positive regulation of transport	GO:0051050	92	0.024
response to heat	GO:0009408	63	0.024
nucleocytoplasmic transport	GO:0006913	72	0.023
regulation of cell cycle phase transition	GO:1901987	130	0.023	Human
regulation of cell division	GO:0051302	72	0.023
histone modification	GO:0016570	106	0.023	Mouse
humoral immune response	GO:0006959	117	0.023
negative regulation of proteolysis	GO:0045861	31	0.023
digestive system development	GO:0055123	149	0.023
appendage development	GO:0048736	401	0.023
indole containing compound biosynthetic process	GO:0042435	4	0.022
positive regulation of phosphorus metabolic process	GO:0010562	139	0.022
establishment of ommatidial planar polarity	GO:0042067	49	0.022
actin filament based process	GO:0030029	220	0.022
regulation of excitatory postsynaptic membrane potential	GO:0060079	3	0.022
positive regulation of cell motility	GO:2000147	3	0.022
negative regulation of biosynthetic process	GO:0009890	277	0.021
positive regulation of cell migration	GO:0030335	2	0.021
activation of innate immune response	GO:0002218	4	0.021
ubiquitin dependent protein catabolic process	GO:0006511	78	0.021
tissue migration	GO:0090130	155	0.021
cell fate determination	GO:0001709	91	0.021
canonical wnt signaling pathway	GO:0060070	21	0.021
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.021
positive regulation of peptidyl tyrosine phosphorylation	GO:0050731	4	0.020
molting cycle	GO:0042303	56	0.020
positive regulation of cellular component organization	GO:0051130	156	0.020
pigmentation	GO:0043473	75	0.020
cellular homeostasis	GO:0019725	80	0.020
regulation of synapse organization	GO:0050807	110	0.020
regulation of programmed cell death	GO:0043067	152	0.020
response to temperature stimulus	GO:0009266	106	0.020
cellular response to biotic stimulus	GO:0071216	4	0.020
ribose phosphate metabolic process	GO:0019693	145	0.019
regulation of malpighian tubule diameter	GO:0035297	3	0.019
response to organic cyclic compound	GO:0014070	89	0.019
embryonic pattern specification	GO:0009880	174	0.019
regulation of transport	GO:0051049	181	0.019
regulation of mitotic cell cycle	GO:0007346	190	0.019	Human
response to oxygen containing compound	GO:1901700	200	0.019
nuclear import	GO:0051170	51	0.019
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.019
positive regulation of epithelial cell differentiation	GO:0030858	1	0.019
peptidyl tyrosine modification	GO:0018212	24	0.019
cell fate commitment involved in formation of primary germ layer	GO:0060795	10	0.019
regulation of transferase activity	GO:0051338	58	0.018
regulation of cellular component size	GO:0032535	98	0.018
regulation of response to biotic stimulus	GO:0002831	63	0.018
small gtpase mediated signal transduction	GO:0007264	88	0.018
peptidyl threonine phosphorylation	GO:0018107	2	0.018
positive regulation of cellular amine metabolic process	GO:0033240	0	0.018
cellular catabolic process	GO:0044248	372	0.018
regulation of embryonic pattern specification	GO:1902875	27	0.018
wing disc morphogenesis	GO:0007472	344	0.018
mrna splicing via spliceosome	GO:0000398	73	0.018
positive regulation of cell proliferation	GO:0008284	47	0.018
molting cycle chitin based cuticle	GO:0007591	56	0.018
negative regulation of kinase activity	GO:0033673	16	0.018
mitotic spindle organization	GO:0007052	220	0.018
regulation of cell shape	GO:0008360	113	0.018
negative regulation of response to stimulus	GO:0048585	258	0.017	Human
negative regulation of cell death	GO:0060548	81	0.017
regulation of neurogenesis	GO:0050767	158	0.017
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.017
establishment or maintenance of cell polarity	GO:0007163	167	0.017
cellular response to growth factor stimulus	GO:0071363	30	0.017
regulation of proteasomal ubiquitin dependent protein catabolic process	GO:0032434	37	0.017
regulation of photoreceptor cell differentiation	GO:0046532	34	0.017
proximal distal pattern formation	GO:0009954	15	0.017
response to external biotic stimulus	GO:0043207	293	0.017
regulation of neuron differentiation	GO:0045664	103	0.017
hemopoiesis	GO:0030097	46	0.017
antimicrobial humoral response	GO:0019730	99	0.017
compound eye retinal cell programmed cell death	GO:0046667	23	0.017
homeostatic process	GO:0042592	199	0.017
dorsal ventral pattern formation	GO:0009953	133	0.017
positive regulation of intracellular signal transduction	GO:1902533	116	0.017	Human
regulation of protein complex disassembly	GO:0043244	29	0.017
cell activation	GO:0001775	9	0.016
ectodermal placode formation	GO:0060788	4	0.016
negative regulation of protein complex disassembly	GO:0043242	23	0.016
cellular response to lipopolysaccharide	GO:0071222	3	0.016
spermatid differentiation	GO:0048515	114	0.016
production of molecular mediator of immune response	GO:0002440	46	0.016
regulation of protein targeting	GO:1903533	29	0.016
regulation of nuclear division	GO:0051783	58	0.016
compound eye photoreceptor cell differentiation	GO:0001751	140	0.016
ameboidal type cell migration	GO:0001667	151	0.016
regulation of cell cycle	GO:0051726	291	0.016	Human
single organism biosynthetic process	GO:0044711	206	0.015
protein processing	GO:0016485	68	0.015
nucleus localization	GO:0051647	34	0.015
imaginal disc derived wing vein morphogenesis	GO:0008586	44	0.015
negative regulation of catalytic activity	GO:0043086	42	0.015
regulation of antimicrobial peptide production	GO:0002784	44	0.015
stem cell development	GO:0048864	79	0.015
single organism cell adhesion	GO:0098602	47	0.015
regulation of cellular component biogenesis	GO:0044087	201	0.015
regulation of intracellular protein transport	GO:0033157	46	0.015
stem cell maintenance	GO:0019827	67	0.015
protein targeting to nucleus	GO:0044744	51	0.015
negative regulation of cellular component organization	GO:0051129	108	0.015
germarium derived female germ line cyst encapsulation	GO:0030708	8	0.015
nitrogen compound transport	GO:0071705	85	0.015
regulation of phosphatase activity	GO:0010921	3	0.015
positive regulation of phosphate metabolic process	GO:0045937	139	0.015
single organism catabolic process	GO:0044712	228	0.015
single organismal cell cell adhesion	GO:0016337	45	0.015
sister chromatid segregation	GO:0000819	92	0.015
positive regulation of molecular function	GO:0044093	136	0.015	Mouse
post embryonic appendage morphogenesis	GO:0035120	385	0.015
organic substance transport	GO:0071702	257	0.015
protein phosphorylation	GO:0006468	169	0.015	Human Mouse
female germ line cyst encapsulation	GO:0048139	8	0.014
rna processing	GO:0006396	147	0.014	Mouse
regulation of cellular component movement	GO:0051270	42	0.014
regulation of synaptic vesicle exocytosis	GO:2000300	3	0.014
proteasome mediated ubiquitin dependent protein catabolic process	GO:0043161	54	0.014
response to extracellular stimulus	GO:0009991	116	0.014
protein maturation	GO:0051604	71	0.014
mitotic dna integrity checkpoint	GO:0044774	75	0.014
tube formation	GO:0035148	21	0.014
dorsal closure	GO:0007391	79	0.014
motor neuron axon guidance	GO:0008045	58	0.014
instar larval development	GO:0002168	55	0.014
synaptic transmission	GO:0007268	288	0.014
negative regulation of transferase activity	GO:0051348	18	0.014
establishment of protein localization	GO:0045184	163	0.014
regulation of cell size	GO:0008361	63	0.014
head involution	GO:0008258	35	0.014
positive regulation of immune response	GO:0050778	63	0.014
insulin receptor signaling pathway	GO:0008286	25	0.014
negative regulation of cell cycle process	GO:0010948	109	0.014	Human
erbb signaling pathway	GO:0038127	58	0.014
histolysis	GO:0007559	102	0.013
g2 dna damage checkpoint	GO:0031572	69	0.013
anatomical structure homeostasis	GO:0060249	97	0.013
establishment of organelle localization	GO:0051656	122	0.013
cellular component disassembly	GO:0022411	46	0.013
positive regulation of neurotransmitter secretion	GO:0001956	2	0.013
convergent extension involved in gastrulation	GO:0060027	2	0.013
axonogenesis	GO:0007409	290	0.013
negative regulation of microtubule polymerization or depolymerization	GO:0031111	21	0.013
negative regulation of phosphorylation	GO:0042326	35	0.013
regulation of actin cytoskeleton organization	GO:0032956	42	0.013
chitin based cuticle development	GO:0040003	49	0.013
pigment cell differentiation	GO:0050931	3	0.013
pattern recognition receptor signaling pathway	GO:0002221	2	0.013
meiotic cell cycle	GO:0051321	171	0.013	Mouse
negative regulation of cellular catabolic process	GO:0031330	34	0.013
outflow tract morphogenesis	GO:0003151	4	0.013
immune response	GO:0006955	246	0.013
histone h3 acetylation	GO:0043966	11	0.013	Mouse
cellular component assembly involved in morphogenesis	GO:0010927	151	0.013
negative regulation of programmed cell death	GO:0043069	72	0.012
negative regulation of protein processing	GO:0010955	31	0.012
positive regulation of neurogenesis	GO:0050769	41	0.012
retina morphogenesis in camera type eye	GO:0060042	2	0.012
nucleobase containing small molecule metabolic process	GO:0055086	174	0.012
regulation of vesicle mediated transport	GO:0060627	59	0.012
regulation of rna splicing	GO:0043484	69	0.012	Mouse
regulation of nucleocytoplasmic transport	GO:0046822	35	0.012
head development	GO:0060322	135	0.012
defense response	GO:0006952	300	0.012	Human
inter male aggressive behavior	GO:0002121	60	0.012
maintenance of location	GO:0051235	73	0.012
regulation of cellular response to oxidative stress	GO:1900407	4	0.012
mitotic dna damage checkpoint	GO:0044773	74	0.012
germ line cyst encapsulation	GO:0048138	8	0.012
compound eye photoreceptor development	GO:0042051	78	0.012
forebrain development	GO:0030900	2	0.011
positive regulation of protein metabolic process	GO:0051247	128	0.011
regulation of protein transport	GO:0051223	57	0.011
negative regulation of mitotic cell cycle phase transition	GO:1901991	103	0.011
taxis	GO:0042330	304	0.011
positive regulation of stem cell differentiation	GO:2000738	3	0.011
salivary gland cell autophagic cell death	GO:0035071	83	0.011
cortical actin cytoskeleton organization	GO:0030866	24	0.011
ecdysone mediated induction of salivary gland cell autophagic cell death	GO:0035072	12	0.011
cell aging	GO:0007569	2	0.011
chromatin remodeling	GO:0006338	72	0.011	Human Mouse
response to lipopolysaccharide	GO:0032496	4	0.011
telencephalon development	GO:0021537	2	0.011
regulation of cellular protein catabolic process	GO:1903362	44	0.011
regulation of dendrite development	GO:0050773	37	0.011
positive regulation of nucleocytoplasmic transport	GO:0046824	24	0.011
negative regulation of wnt signaling pathway	GO:0030178	28	0.011
medulla oblongata development	GO:0021550	2	0.011
wnt signaling pathway	GO:0016055	98	0.011
protein import into nucleus	GO:0006606	51	0.011
regulation of response to dna damage stimulus	GO:2001020	23	0.011	Human
cell fate specification	GO:0001708	71	0.011	Worm
negative regulation of immune system process	GO:0002683	50	0.011
wing disc dorsal ventral pattern formation	GO:0048190	47	0.011
stem cell proliferation	GO:0072089	88	0.011
substrate dependent cell migration	GO:0006929	3	0.011
neuron death	GO:0070997	27	0.010
cytoskeleton dependent cytokinesis	GO:0061640	81	0.010
regulation of response to oxidative stress	GO:1902882	4	0.010
circulatory system process	GO:0003013	37	0.010
intracellular protein transport	GO:0006886	104	0.010
regulation of cell junction assembly	GO:1901888	2	0.010
response to light stimulus	GO:0009416	124	0.010
peptidyl threonine modification	GO:0018210	3	0.010
proteasomal protein catabolic process	GO:0010498	59	0.010
peripheral nervous system development	GO:0007422	52	0.010
jak stat cascade	GO:0007259	49	0.010
eye photoreceptor cell differentiation	GO:0001754	145	0.010
regulation of immune effector process	GO:0002697	52	0.010
organelle fission	GO:0048285	340	0.010	Mouse
skeletal muscle organ development	GO:0060538	48	0.010
positive regulation of hydrolase activity	GO:0051345	78	0.010
protein import	GO:0017038	55	0.010
actin filament bundle organization	GO:0061572	28	0.010
regulation of erk1 and erk2 cascade	GO:0070372	39	0.010
positive regulation of immune system process	GO:0002684	68	0.010
cellular protein catabolic process	GO:0044257	83	0.010
defense response to other organism	GO:0098542	225	0.010

fs(1)h disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of cellular proliferation	DOID:14566	0.059
cancer	DOID:162	0.059
disease of anatomical entity	DOID:7	0.014

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