Drosophila melanogaster

132 known processes

Fs(2)Ket (Dmel_CG2637)

Female sterile (2) Ketel

(Aliases: fs(2)ltoHD43,kettle,Fs(2)Sz7,Fs(2)Sz6,Hon,Dmel\CG2637,CG2637,Kpnb1,IMPbeta1,Ketel,dKap-beta,Fs(2)Hon,ketel,fs(2)lto2,imp-beta,38E.11,Ket,fs(2)lo-B)

Fs(2)Ket biological process predictions


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Biological processGO term IDProcess sizeProbabilityFunc Analog Org
chromosome organizationGO:00512763600.998
nuclear divisionGO:00002803320.991
organelle assemblyGO:00709251980.971
centrosome cycleGO:00070981370.960
oocyte developmentGO:00485991240.941
pronuclear migrationGO:003504640.935
chromatin remodelingGO:0006338720.912
establishment of localization in cellGO:00516494020.899
mitotic spindle organizationGO:00070522200.890
Worm
rna localizationGO:00064031150.838
organelle localizationGO:00516401480.828
microtubule organizing center organizationGO:00310231680.806
fertilizationGO:0009566260.792
oocyte differentiationGO:00099941450.754
intracellular mrna localization involved in pattern specification processGO:0060810560.738
mitotic nuclear divisionGO:00070672130.732
intracellular mrna localization involved in anterior posterior axis specificationGO:0060811530.722
cellular macromolecule localizationGO:00707272200.700
macromolecular complex assemblyGO:00650032560.668
spindle organizationGO:00070512530.666
Worm
single fertilizationGO:0007338240.660
intracellular mrna localizationGO:0008298660.645
protein dna complex assemblyGO:0065004630.638
organelle fissionGO:00482853400.624
regulation of oocyte developmentGO:0060281270.616
oocyte microtubule cytoskeleton organizationGO:0016325350.615
single organism cellular localizationGO:19025801800.606
oocyte constructionGO:00073081120.600
protein complex assemblyGO:00064612000.567
protein modification processGO:00362114380.547
Yeast
positive regulation of macromolecule metabolic processGO:00106044050.543
pole plasm mrna localizationGO:0019094490.539
nucleus localizationGO:0051647340.539
axis specificationGO:00097981670.539
meiotic nuclear divisionGO:00071261510.538
centrosome organizationGO:00512971630.534
organic substance transportGO:00717022570.533
cell maturationGO:00484691440.509
regulation of response to stressGO:00801342000.491
positive regulation of gene expressionGO:00106282900.461
male gamete generationGO:00482322010.456
embryo development ending in birth or egg hatchingGO:00097921520.440
Worm
regulation of pole plasm oskar mrna localizationGO:0007317270.435
developmental maturationGO:00217001720.425
regulation of nuclear divisionGO:0051783580.415
lipid biosynthetic processGO:0008610460.400
Yeast
regulation of cell cycleGO:00517262910.398
cell divisionGO:00513012480.384
positive regulation of cellular amino acid metabolic processGO:004576400.376
single organism intracellular transportGO:19025822070.354
cellular macromolecular complex assemblyGO:00346221530.349
oocyte axis specificationGO:00073091080.340
intracellular transportGO:00469072280.334
maternal determination of anterior posterior axis embryoGO:0008358740.327
embryonic axis specificationGO:00005781070.317
negative regulation of gene expressionGO:00106293870.305
response to other organismGO:00517072930.302
regulation of mitotic cell cycleGO:00073461900.296
regionalizationGO:00030024160.291
positive regulation of cellular biosynthetic processGO:00313283160.288
regulation of cytoskeleton organizationGO:0051493890.282
cellular protein localizationGO:00346131600.280
chorion containing eggshell formationGO:00073041050.276
taxisGO:00423303040.275
epithelial cell developmentGO:00020642740.270
intracellular protein transportGO:00068861040.265
chromatin organizationGO:00063252070.263
positive regulation of response to stimulusGO:00485843230.258
oocyte dorsal ventral axis specificationGO:0007310340.253
spermatogenesisGO:00072832000.252
embryonic cleavageGO:004001650.249
protein localizationGO:00081042840.249
dna conformation changeGO:00711031050.244
embryonic pattern specificationGO:00098801740.237
anterior posterior pattern specificationGO:00099521360.236
regulation of cell cycle processGO:00105641810.221
larval developmentGO:00021641040.215
centrosome duplicationGO:00512981210.211
ubiquitin dependent protein catabolic processGO:0006511780.210
oocyte anterior posterior axis specificationGO:0007314720.210
response to abiotic stimulusGO:00096283410.203
positive regulation of transcription dna templatedGO:00458932660.195
regulation of cellular localizationGO:00603411360.193
pole plasm rna localizationGO:0007316520.189
nucleocytoplasmic transportGO:0006913720.186
establishment of protein localizationGO:00451841630.186
actin filament based processGO:00300292200.182
regulation of intracellular transportGO:0032386640.181
regulation of embryonic pattern specificationGO:1902875270.180
protein complex biogenesisGO:00702712010.179
establishment or maintenance of microtubule cytoskeleton polarityGO:0030951410.177
positive regulation of macromolecule biosynthetic processGO:00105572830.175
mitotic g2 m transition checkpointGO:0044818700.173
tripartite regional subdivisionGO:00073511030.172
pole plasm assemblyGO:0007315610.166
cellular component assembly involved in morphogenesisGO:00109271510.164
dna packagingGO:0006323910.163
pole plasm oskar mrna localizationGO:0045451460.162
positive regulation of nucleic acid templated transcriptionGO:19035082660.161
body morphogenesisGO:001017120.158
protein transportGO:00150311550.152
defense response to other organismGO:00985422250.151
cellular protein complex assemblyGO:0043623710.147
response to hypoxiaGO:0001666530.139
chromatin assembly or disassemblyGO:0006333520.136
microtubule polymerization or depolymerizationGO:0031109390.134
regulation of mitotic cell cycle phase transitionGO:19019901300.133
nuclear transportGO:0051169720.132
cellular protein modification processGO:00064644380.130
Yeast
dorsal ventral pattern formationGO:00099531330.126
response to external biotic stimulusGO:00432072930.125
cellular component disassemblyGO:0022411460.124
chromatin assemblyGO:0031497480.123
regulation of multi organism processGO:00439001310.123
regulation of cysteine type endopeptidase activityGO:2000116270.123
regulation of establishment of protein localizationGO:0070201610.123
negative regulation of nitrogen compound metabolic processGO:00511722650.122
localization of cellGO:00516742570.118
ribonucleoprotein complex assemblyGO:0022618230.117
regulation of organelle organizationGO:00330431960.113
muscle structure developmentGO:00610612240.112
regulation of alternative mrna splicing via spliceosomeGO:0000381600.111
sensory perception of soundGO:0007605560.107
response to biotic stimulusGO:00096072940.106
neurological system processGO:00508773580.105
regulation of localizationGO:00328792750.103
regulation of cytoplasmic transportGO:1903649470.099
chemotaxisGO:00069352490.098
establishment or maintenance of cytoskeleton polarityGO:0030952440.098
peptidyl lysine modificationGO:0018205570.097
positive regulation of nitrogen compound metabolic processGO:00511733540.097
Yeast
regulation of meiosisGO:004002030.092
dna metabolic processGO:00062592270.091
positive regulation of cellular amine metabolic processGO:003324000.090
segmentationGO:00352822070.086
positive regulation of protein metabolic processGO:00512471280.086
chromatin modificationGO:00165681470.086
positive regulation of signalingGO:00230562430.084
myotube cell developmentGO:001490430.083
meiotic cell cycleGO:00513211710.082
positive regulation of signal transductionGO:00099672230.082
amine metabolic processGO:0009308120.082
Yeast
establishment of nucleus localizationGO:0040023260.081
spermatid differentiationGO:00485151140.081
nuclear exportGO:0051168240.079
apoptotic processGO:00069151590.075
positive regulation of biosynthetic processGO:00098913160.074
ribonucleoprotein complex biogenesisGO:0022613310.074
modification dependent macromolecule catabolic processGO:0043632790.073
striated muscle cell developmentGO:0055002500.073
ommatidial rotationGO:0016318200.071
response to decreased oxygen levelsGO:0036293580.071
regulation of gene expression epigeneticGO:00400291280.071
establishment of organelle localizationGO:00516561220.071
actin cytoskeleton organizationGO:00300362060.070
eggshell chorion gene amplificationGO:000730790.069
positive regulation of developmental processGO:00510941430.069
positive regulation of protein import into nucleusGO:0042307210.069
male pronucleus assemblyGO:003503960.068
spindle assembly involved in mitosisGO:0090307500.068
epithelial cell differentiationGO:00308553220.068
response to bacteriumGO:00096171980.067
synaptic transmissionGO:00072682880.067
regulation of mrna metabolic processGO:1903311720.063
negative regulation of rna biosynthetic processGO:19026792400.063
regulation of reproductive processGO:2000241540.063
posttranscriptional regulation of gene expressionGO:00106081450.062
cellular protein catabolic processGO:0044257830.061
organonitrogen compound metabolic processGO:19015643180.060
Yeast
germarium derived oocyte fate determinationGO:0007294260.060
spindle assembly involved in female meiosisGO:0007056140.059
myofibril assemblyGO:0030239360.059
response to reactive oxygen speciesGO:0000302240.059
positive regulation of rna biosynthetic processGO:19026802660.058
spindle assembly involved in meiosisGO:0090306200.058
positive regulation of mitotic cell cycleGO:0045931340.058
immune responseGO:00069552460.058
multicellular organismal agingGO:00102591400.057
defense responseGO:00069523000.056
cell cycle checkpointGO:0000075950.056
positive regulation of cell cycleGO:0045787430.056
cytokinesisGO:0000910900.055
spindle assemblyGO:0051225800.054
regulation of protein localizationGO:0032880760.053
regulation of protein metabolic processGO:00512462560.053
Yeast
positive regulation of cell cycle processGO:0090068280.052
striated muscle cell differentiationGO:0051146900.051
regulation of cell divisionGO:0051302720.051
regulation of apoptotic processGO:00429811300.050
blastoderm segmentationGO:00073501590.050
regulation of cellular component biogenesisGO:00440872010.049
rrna processingGO:000636430.049
establishment of rna localizationGO:0051236470.049
anterior posterior axis specificationGO:00099481090.049
cytoplasmic transportGO:00164821300.049
cell fate determinationGO:0001709910.048
positive regulation of cell communicationGO:00106472500.047
establishment of protein localization to organelleGO:0072594620.046
chromosome condensationGO:0030261410.046
multi organism behaviorGO:00517051750.046
rna transportGO:0050658460.045
digestive tract developmentGO:00485651490.045
reproductive system developmentGO:0061458740.045
negative regulation of nucleic acid templated transcriptionGO:19035072400.045
regulation of transportGO:00510491810.045
gene silencingGO:00164581380.045
oocyte nucleus localization involved in oocyte dorsal ventral axis specificationGO:0051663120.044
response to oxygen levelsGO:0070482590.044
digestive system developmentGO:00551231490.042
chromatin silencingGO:0006342760.042
modification dependent protein catabolic processGO:0019941780.042
negative regulation of macromolecule biosynthetic processGO:00105582700.040
negative regulation of growthGO:0045926840.040
g1 s transition of mitotic cell cycleGO:0000082310.039
response to temperature stimulusGO:00092661060.039
regulation of cellular amine metabolic processGO:003323830.038
ribonucleoprotein complex subunit organizationGO:0071826280.038
protein localization to organelleGO:0033365820.038
protein catabolic processGO:00301631010.037
ovarian follicle cell developmentGO:00307072480.037
rna splicingGO:0008380830.037
positive regulation of nucleocytoplasmic transportGO:0046824240.037
regulation of transcription from rna polymerase ii promoterGO:00063573780.036
meiosis iGO:0007127590.036
actin filament organizationGO:00070151260.035
nucleobase containing compound transportGO:0015931560.035
protein processingGO:0016485680.034
rna processingGO:00063961470.034
regulation of cellular ketone metabolic processGO:001056530.033
sensory perceptionGO:00076001960.033
translationGO:0006412690.033
negative regulation of gene expression epigeneticGO:0045814770.033
microtubule cytoskeleton organization involved in mitosisGO:1902850520.033
regulation of cell maturationGO:1903429270.033
meiotic cell cycle processGO:19030461320.032
reproductive structure developmentGO:0048608740.032
development of primary sexual characteristicsGO:0045137500.032
nitrogen compound transportGO:0071705850.032
single organism biosynthetic processGO:00447112060.032
Yeast
cellular response to decreased oxygen levelsGO:0036294300.032
cell migrationGO:00164772380.031
regulation of microtubule cytoskeleton organizationGO:0070507410.031
vesicle mediated transportGO:00161923810.031
positive regulation of multicellular organismal processGO:00512401430.030
establishment of meiotic spindle orientationGO:005129620.030
regulation of protein catabolic processGO:0042176550.030
cell motilityGO:00488702510.029
oxoacid metabolic processGO:00434361030.029
regulation of nucleobase containing compound transportGO:003223940.029
protein targeting to nucleusGO:0044744510.029
positive regulation of rna metabolic processGO:00512542710.028
determination of adult lifespanGO:00083401370.028
regulation of protein transportGO:0051223570.028
cell growthGO:00160491080.028
nuclear envelope organizationGO:000699870.027
spermatid developmentGO:0007286980.027
cellular amine metabolic processGO:0044106120.027
Yeast
neuron projection guidanceGO:00974852410.027
meiotic chromosome segregationGO:0045132590.027
positive regulation of protein modification processGO:0031401580.027
regulation of transcription by chromatin organizationGO:003440130.027
protein polymerizationGO:0051258420.026
negative regulation of nucleobase containing compound metabolic processGO:00459342610.026
eggshell formationGO:00307031050.026
cellular response to abiotic stimulusGO:0071214580.026
regulation of endopeptidase activityGO:0052548360.026
regulation of notch signaling pathwayGO:00085931000.026
muscle cell developmentGO:0055001500.026
notch signaling pathwayGO:00072191200.026
mitotic sister chromatid segregationGO:0000070870.026
regulation of cell cycle phase transitionGO:19019871300.025
protein modification by small protein conjugation or removalGO:00706471060.025
Yeast
eggshell chorion assemblyGO:0007306660.025
proteolysisGO:00065081920.025
regulation of nucleocytoplasmic transportGO:0046822350.025
innate immune responseGO:00450871440.025
asymmetric cell divisionGO:0008356370.024
deathGO:00162652840.024
cellular response to oxygen levelsGO:0071453300.024
oocyte maturationGO:000155630.024
regulation of microtubule based processGO:0032886490.024
positive regulation of histone acetylationGO:003506630.023
regulation of protein modification processGO:00313991120.023
Yeast
atp dependent chromatin remodelingGO:0043044220.023
cell adhesionGO:00071551360.023
regulation of cellular response to stressGO:0080135890.023
positive regulation of intracellular protein transportGO:0090316300.023
positive regulation of apoptotic processGO:0043065470.023
positive regulation of intracellular transportGO:0032388420.022
centriole replicationGO:0007099240.022
regulation of phosphatase activityGO:001092130.022
response to heatGO:0009408630.022
nucleoside triphosphate metabolic processGO:00091411200.022
camera type eye developmentGO:004301040.022
ribonucleotide metabolic processGO:00092591450.022
transcription from rna polymerase ii promoterGO:00063663680.022
dorsal ventral axis specificationGO:0009950660.021
anterior posterior axis specification embryoGO:00085951030.021
growthGO:00400073590.021
mitotic spindle checkpointGO:0071174110.021
microtubule polymerizationGO:0046785150.021
protein import into nucleusGO:0006606510.021
positive regulation of cellular protein metabolic processGO:00322701180.020
actomyosin structure organizationGO:0031032560.020
female meiosis iGO:000714480.020
positive regulation of developmental growthGO:0048639620.020
dna methylationGO:000630640.020
regulation of multicellular organismal developmentGO:20000264140.020
regulation of gliogenesisGO:0014013110.020
regulation of actin cytoskeleton organizationGO:0032956420.020
negative regulation of organelle organizationGO:0010639560.019
positive regulation of transportGO:0051050920.019
negative regulation of mitotic cell cycle phase transitionGO:19019911030.019
response to oxidative stressGO:0006979860.019
organic acid metabolic processGO:00060821030.019
regulation of nuclear transcribed mrna poly a tail shorteningGO:006021140.019
intercellular bridge organizationGO:0043063140.019
regulation of mitosisGO:0007088560.019
developmental growthGO:00485892800.018
mitotic dna integrity checkpointGO:0044774750.018
cellular protein complex disassemblyGO:0043624350.018
multicellular organismal homeostasisGO:0048871410.018
negative regulation of rna metabolic processGO:00512532510.018
dna amplificationGO:0006277110.018
negative regulation of biosynthetic processGO:00098902770.018
cellular nitrogen compound catabolic processGO:00442701650.017
regulation of intracellular protein transportGO:0033157460.017
establishment of epithelial cell apical basal polarityGO:0045198100.017
regulation of cellular amino acid metabolic processGO:000652100.017
somatic muscle developmentGO:0007525660.017
regulation of embryonic developmentGO:0045995680.017
protein targetingGO:0006605640.017
skeletal muscle organ developmentGO:0060538480.017
attachment of spindle microtubules to kinetochoreGO:000860850.017
genitalia developmentGO:0048806260.017
regulation of cellular protein metabolic processGO:00322682430.016
Yeast
microtubule anchoringGO:0034453110.016
ncrna metabolic processGO:0034660430.016
cellular response to hypoxiaGO:0071456280.016
carbohydrate derivative metabolic processGO:19011352170.016
alternative mrna splicing via spliceosomeGO:0000380600.016
gonad developmentGO:0008406500.016
oocyte microtubule cytoskeleton polarizationGO:0008103220.016
regulation of proteolysisGO:0030162870.016
positive regulation of immune responseGO:0050778630.016
regulation of protein acetylationGO:190198370.016
negative regulation of cell cycle processGO:00109481090.015
atp metabolic processGO:0046034490.015
cellular response to oxygen containing compoundGO:1901701790.015
negative regulation of developmental processGO:00510932010.015
negative regulation of transcription dna templatedGO:00458922370.015
secretionGO:00469031090.015
nucleobase containing small molecule metabolic processGO:00550861740.015
gland morphogenesisGO:00226121450.014
protein maturationGO:0051604710.014
mrna splicing via spliceosomeGO:0000398730.014
regulation of cell differentiationGO:00455953020.014
positive regulation of phosphorylationGO:0042327870.014
lipid localizationGO:0010876540.014
sister chromatid segregationGO:0000819920.014
female meiotic divisionGO:0007143700.014
detection of stimulusGO:00516061560.014
regulation of cell proliferationGO:00421271630.014
regulation of gene silencingGO:0060968630.014
digestive tract morphogenesisGO:00485461270.014
programmed cell deathGO:00125012570.014
small molecule metabolic processGO:00442813050.014
Yeast
regulation of mrna splicing via spliceosomeGO:0048024640.014
pronuclear fusionGO:000734440.014
regulation of chromatin silencingGO:0031935360.014
skeletal muscle fiber developmentGO:004874130.014
homeostatic processGO:00425921990.014
muscle cell differentiationGO:00426921030.013
cellular homeostasisGO:0019725800.013
photoreceptor cell developmentGO:0042461960.013
nucleosome organizationGO:0034728590.013
nucleosome assemblyGO:0006334350.013
regulation of mrna processingGO:0050684710.013
carboxylic acid metabolic processGO:0019752920.013
negative regulation of signal transduction by p53 class mediatorGO:190179710.013
cell deathGO:00082192790.013
cell proliferationGO:00082832990.013
protein modification by small protein conjugationGO:0032446790.013
positive regulation of defense responseGO:0031349590.013
regulation of protein processingGO:0070613320.013
macromolecule catabolic processGO:00090571610.013
regulation of cell developmentGO:00602842150.013
negative regulation of proteasomal protein catabolic processGO:1901799160.013
regulation of phosphorylationGO:00423251470.012
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.012
negative regulation of mitotic cell cycleGO:00459301090.012
negative regulation of cysteine type endopeptidase activity involved in apoptotic processGO:004315420.012
posttranscriptional gene silencing by rnaGO:0035194450.012
positive regulation of nucleobase containing compound metabolic processGO:00459353320.012
Yeast
cellular catabolic processGO:00442483720.012
axonogenesisGO:00074092900.012
positive regulation of growthGO:0045927750.012
positive regulation of protein localization to nucleusGO:1900182210.012
positive regulation of cell developmentGO:0010720610.012
centrosome separationGO:0051299200.012
positive regulation of nervous system developmentGO:0051962690.012
endocytosisGO:00068973100.012
muscle organ developmentGO:00075171270.012
negative regulation of multicellular organismal processGO:00512411420.012
spindle assembly involved in female meiosis iGO:000705750.011
regulation of production of molecular mediator of immune responseGO:0002700440.011
positive regulation of transcription factor import into nucleusGO:0042993190.011
negative regulation of proteolysisGO:0045861310.011
regulation of canonical wnt signaling pathwayGO:0060828150.011
phagocytosisGO:00069092150.011
positive regulation of immune system processGO:0002684680.011
cell cycle phase transitionGO:00447701400.011
covalent chromatin modificationGO:00165691060.011
maintenance of location in cellGO:0051651280.011
g2 dna damage checkpointGO:0031572690.011
defense response to bacteriumGO:00427421780.011
regulation of immune effector processGO:0002697520.011
regulation of protein export from nucleusGO:004682530.011
protein importGO:0017038550.011
mrna metabolic processGO:00160711240.011
regulation of meiotic cell cycleGO:005144590.011
regulation of cellular catabolic processGO:00313291570.011
Yeast
gene silencing by rnaGO:0031047570.010
negative regulation of phosphatase activityGO:001092330.010
histone modificationGO:00165701060.010
positive regulation of innate immune responseGO:0045089380.010
nuclear importGO:0051170510.010
nucleus organizationGO:0006997450.010
Yeast
regulation of cell deathGO:00109411730.010

Fs(2)Ket disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.056
disease of cellular proliferationDOID:1456600.023
cancerDOID:16200.023
organ system cancerDOID:005068600.023
nervous system diseaseDOID:86300.013