Drosophila melanogaster

72 known processes

Sam-S (Dmel_CG2674)

S-adenosylmethionine Synthetase

(Aliases: Su(z)5,CG2674,Dmel\CG2674,SamS,METK,M(2)21AB,M(2)21A-B,m(2)21ab)

Sam-S biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
chromatin organizationGO:00063252070.840
negative regulation of nucleobase containing compound metabolic processGO:00459342610.829
negative regulation of cellular biosynthetic processGO:00313272770.623
negative regulation of nitrogen compound metabolic processGO:00511722650.557
chromosome organizationGO:00512763600.549
organonitrogen compound metabolic processGO:19015643180.392
purine containing compound metabolic processGO:00725211550.389
gene silencingGO:00164581380.345
organophosphate metabolic processGO:00196371950.311
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.309
establishment of localization in cellGO:00516494020.267
peptidyl lysine modificationGO:0018205570.264
nucleoside metabolic processGO:00091161270.264
endocytosisGO:00068973100.233
heterocycle catabolic processGO:00467001660.212
small molecule metabolic processGO:00442813050.181
purine ribonucleotide metabolic processGO:00091501450.176
negative regulation of biosynthetic processGO:00098902770.167
immune system developmentGO:0002520570.161
cellular catabolic processGO:00442483720.158
histone modificationGO:00165701060.150
response to biotic stimulusGO:00096072940.147
purine nucleotide metabolic processGO:00061631460.145
covalent chromatin modificationGO:00165691060.143
negative regulation of cellular metabolic processGO:00313243820.134
purine ribonucleoside metabolic processGO:00461281270.134
posttranscriptional regulation of gene expressionGO:00106081450.133
nucleotide metabolic processGO:00091171610.132
regulation of cell cycleGO:00517262910.131
deathGO:00162652840.127
nucleobase containing compound catabolic processGO:00346551650.125
purine nucleoside metabolic processGO:00422781270.122
nucleoside phosphate metabolic processGO:00067531620.121
catabolic processGO:00090564090.109
posttranscriptional gene silencingGO:0016441460.104
response to oxidative stressGO:0006979860.101
aromatic compound catabolic processGO:00194391660.101
organic acid metabolic processGO:00060821030.100
cellular protein modification processGO:00064644380.099
ribonucleoside metabolic processGO:00091191270.097
negative regulation of macromolecule biosynthetic processGO:00105582700.095
cell deathGO:00082192790.093
negative regulation of nucleic acid templated transcriptionGO:19035072400.092
organonitrogen compound catabolic processGO:19015651280.090
ribonucleoside triphosphate catabolic processGO:00092031080.087
negative regulation of rna biosynthetic processGO:19026792400.087
single organism membrane fusionGO:0044801420.085
cellular nitrogen compound catabolic processGO:00442701650.085
programmed cell deathGO:00125012570.085
regulation of translationGO:0006417560.085
purine ribonucleoside monophosphate metabolic processGO:0009167500.084
ribonucleotide metabolic processGO:00092591450.084
chromatin modificationGO:00165681470.084
regulation of multicellular organism growthGO:0040014400.081
translationGO:0006412690.080
carbohydrate derivative metabolic processGO:19011352170.080
nucleoside triphosphate metabolic processGO:00091411200.079
axonogenesisGO:00074092900.075
ribose phosphate metabolic processGO:00196931450.075
neuron projection guidanceGO:00974852410.074
oxoacid metabolic processGO:00434361030.073
columnar cuboidal epithelial cell differentiationGO:00020652560.073
response to external biotic stimulusGO:00432072930.073
chromatin assemblyGO:0031497480.072
cellular response to dna damage stimulusGO:00069742230.070
multicellular organism growthGO:0035264460.068
organic substance catabolic processGO:19015753080.067
purine ribonucleotide catabolic processGO:00091541090.066
learningGO:0007612750.066
gene silencing by rnaGO:0031047570.064
positive regulation of growthGO:0045927750.063
purine nucleoside catabolic processGO:00061521120.062
organonitrogen compound biosynthetic processGO:19015661170.062
cellular protein localizationGO:00346131600.061
regulation of gene expression epigeneticGO:00400291280.060
cellular macromolecule catabolic processGO:00442651360.058
growthGO:00400073590.058
regulation of immune system processGO:00026821760.057
response to other organismGO:00517072930.057
regulation of molecular functionGO:00650092170.055
protein complex biogenesisGO:00702712010.055
nucleobase containing small molecule metabolic processGO:00550861740.055
purine nucleoside monophosphate metabolic processGO:0009126500.055
negative regulation of rna metabolic processGO:00512532510.054
carbohydrate derivative catabolic processGO:19011361180.054
amine metabolic processGO:0009308120.054
intracellular transportGO:00469072280.052
ribonucleoside triphosphate metabolic processGO:00091991190.052
chromatin silencingGO:0006342760.052
morphogenesis of an epitheliumGO:00020092760.051
purine containing compound catabolic processGO:00725231120.051
nuclear divisionGO:00002803320.051
purine ribonucleoside triphosphate catabolic processGO:00092071080.051
epithelial cell differentiationGO:00308553220.051
embryo development ending in birth or egg hatchingGO:00097921520.050
reproductive structure developmentGO:0048608740.050
ribonucleoside monophosphate metabolic processGO:0009161510.050
positive regulation of biosynthetic processGO:00098913160.049
regulation of programmed cell deathGO:00430671520.048
protein complex disassemblyGO:0043241360.048
organic cyclic compound catabolic processGO:19013611680.048
negative regulation of gene expressionGO:00106293870.047
atp metabolic processGO:0046034490.047
negative regulation of apoptotic processGO:0043066630.047
immune system processGO:00023763470.046
mitotic sister chromatid segregationGO:0000070870.046
matingGO:00076181200.046
dna damage checkpointGO:0000077780.046
purine nucleoside triphosphate catabolic processGO:00091461080.045
apoptotic processGO:00069151590.045
nucleoside catabolic processGO:00091641120.045
negative regulation of developmental processGO:00510932010.044
nucleoside triphosphate catabolic processGO:00091431080.043
protein acetylationGO:0006473390.042
regulation of growthGO:00400082330.042
neurological system processGO:00508773580.042
regulation of protein metabolic processGO:00512462560.042
single organism behaviorGO:00447083910.042
mitotic dna damage checkpointGO:0044773740.041
determination of adult lifespanGO:00083401370.041
response to oxygen containing compoundGO:19017002000.041
stem cell maintenanceGO:0019827670.039
positive regulation of developmental growthGO:0048639620.039
sister chromatid segregationGO:0000819920.039
protein modification processGO:00362114380.039
purine nucleotide catabolic processGO:00061951090.039
nucleotide catabolic processGO:00091661090.039
ribonucleoside monophosphate catabolic processGO:0009158390.038
regulation of cell cycle processGO:00105641810.037
positive regulation of multicellular organism growthGO:0040018210.036
regulation of catalytic activityGO:00507901850.036
maintenance of locationGO:0051235730.035
cell cell signaling involved in cell fate commitmentGO:00451682100.035
intracellular signal transductionGO:00355563000.035
localization of cellGO:00516742570.035
eye photoreceptor cell differentiationGO:00017541450.034
regulation of gene silencingGO:0060968630.034
organelle fissionGO:00482853400.034
transcription from rna polymerase ii promoterGO:00063663680.033
regulation of cell deathGO:00109411730.033
positive regulation of nucleobase containing compound metabolic processGO:00459353320.033
glycosyl compound catabolic processGO:19016581120.033
protein acylationGO:0043543420.032
purine ribonucleoside triphosphate metabolic processGO:00092051190.032
mitotic nuclear divisionGO:00070672130.032
ribonucleoside catabolic processGO:00424541120.031
nucleoside phosphate catabolic processGO:19012921100.031
posttranscriptional gene silencing by rnaGO:0035194450.031
defense responseGO:00069523000.031
positive regulation of gene expressionGO:00106282900.031
dna integrity checkpointGO:0031570810.031
rna localizationGO:00064031150.030
organic substance transportGO:00717022570.030
organophosphate biosynthetic processGO:0090407460.030
sensory perception of soundGO:0007605560.029
purine nucleoside triphosphate metabolic processGO:00091441190.029
associative learningGO:0008306650.029
negative regulation of response to stimulusGO:00485852580.029
axon guidanceGO:00074112330.029
homeostatic processGO:00425921990.029
macromolecule catabolic processGO:00090571610.029
regulation of nervous system developmentGO:00519602480.029
positive regulation of nucleic acid templated transcriptionGO:19035082660.028
purine ribonucleoside monophosphate catabolic processGO:0009169380.028
cellular homeostasisGO:0019725800.028
negative regulation of cell cycle processGO:00109481090.028
hemopoiesisGO:0030097460.028
body morphogenesisGO:001017120.027
purine ribonucleoside catabolic processGO:00461301120.027
meiotic nuclear divisionGO:00071261510.027
enteroendocrine cell differentiationGO:003588310.027
positive regulation of cell deathGO:0010942690.026
macromolecular complex assemblyGO:00650032560.026
regulation of developmental growthGO:00486381740.026
cytoplasmic transportGO:00164821300.026
sex differentiationGO:0007548810.026
protein localization to organelleGO:0033365820.026
single organism biosynthetic processGO:00447112060.026
positive regulation of immune system processGO:0002684680.026
internal protein amino acid acetylationGO:0006475380.026
positive regulation of cell migrationGO:003033520.026
chemotaxisGO:00069352490.025
cellular amino acid metabolic processGO:0006520610.025
regulation of cellular protein metabolic processGO:00322682430.025
organelle localizationGO:00516401480.025
positive regulation of rna biosynthetic processGO:19026802660.025
reproductive system developmentGO:0061458740.025
lipid localizationGO:0010876540.025
negative regulation of cellular component organizationGO:00511291080.024
regulation of anatomical structure morphogenesisGO:00226032420.024
positive regulation of catalytic activityGO:00430851180.024
ovarian follicle cell developmentGO:00307072480.024
mesenchymal cell differentiationGO:004876210.023
genitalia developmentGO:0048806260.023
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281250.023
appendage developmentGO:00487364010.023
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.023
cell migrationGO:00164772380.022
response to bacteriumGO:00096171980.022
regulation of mitotic cell cycleGO:00073461900.022
negative regulation of cell deathGO:0060548810.022
dorsal ventral pattern formationGO:00099531330.022
imaginal disc derived wing morphogenesisGO:00074763370.022
cellular response to chemical stimulusGO:00708871990.022
positive regulation of translationGO:0045727120.022
regulation of proteolysisGO:0030162870.022
dna metabolic processGO:00062592270.022
atp catabolic processGO:0006200380.021
protein modification by small protein conjugation or removalGO:00706471060.021
organophosphate catabolic processGO:00464341120.021
phagocytosisGO:00069092150.021
response to alcoholGO:0097305950.021
ribonucleotide catabolic processGO:00092611090.021
stem cell developmentGO:0048864790.021
carbohydrate metabolic processGO:0005975820.020
cell cycle phase transitionGO:00447701400.020
cation homeostasisGO:0055080510.020
rna interferenceGO:0016246270.020
glycosyl compound metabolic processGO:19016571270.020
developmental growthGO:00485892800.020
dna replicationGO:0006260480.019
positive regulation of protein metabolic processGO:00512471280.019
eye developmentGO:00016543230.019
regulation of cell differentiationGO:00455953020.019
nucleoside monophosphate metabolic processGO:0009123520.019
cellular amine metabolic processGO:0044106120.019
positive regulation of cellular protein metabolic processGO:00322701180.019
regulation of notch signaling pathwayGO:00085931000.019
nucleocytoplasmic transportGO:0006913720.019
regulation of transcription from rna polymerase ii promoterGO:00063573780.019
vesicle mediated transportGO:00161923810.019
response to radiationGO:00093141550.019
negative regulation of cell differentiationGO:00455961430.018
cellular response to dsrnaGO:0071359150.018
negative regulation of transcription dna templatedGO:00458922370.017
nuclear transportGO:0051169720.017
cellular macromolecular complex assemblyGO:00346221530.017
compound eye photoreceptor cell differentiationGO:00017511400.017
cellular response to organic cyclic compoundGO:0071407320.017
regulation of organelle organizationGO:00330431960.017
ncrna metabolic processGO:0034660430.017
learning or memoryGO:00076111410.017
tissue deathGO:00162711020.017
regulation of apoptotic processGO:00429811300.017
hematopoietic or lymphoid organ developmentGO:0048534570.017
adult behaviorGO:00305341370.017
cellular response to decreased oxygen levelsGO:0036294300.016
mitotic dna integrity checkpointGO:0044774750.016
alcohol metabolic processGO:0006066250.016
appendage morphogenesisGO:00351073970.016
protein transmembrane transportGO:007180640.016
negative regulation of cellular protein metabolic processGO:0032269850.016
developmental maturationGO:00217001720.016
regulation of mitotic cell cycle phase transitionGO:19019901300.016
protein localizationGO:00081042840.016
regulation of cellular localizationGO:00603411360.016
response to glucoseGO:000974920.016
peptidyl amino acid modificationGO:00181931050.015
positive regulation of cellular amine metabolic processGO:003324000.015
nitrogen compound transportGO:0071705850.015
cell cycle checkpointGO:0000075950.015
organic hydroxy compound biosynthetic processGO:1901617210.015
regulation of chromatin silencingGO:0031935360.015
regulation of cellular component biogenesisGO:00440872010.015
g2 dna damage checkpointGO:0031572690.015
protein dna complex subunit organizationGO:0071824860.015
regulation of localizationGO:00328792750.015
cellular component disassemblyGO:0022411460.015
meiotic cell cycleGO:00513211710.014
stem cell differentiationGO:00488631170.014
positive regulation of macromolecule biosynthetic processGO:00105572830.014
mitotic g2 m transition checkpointGO:0044818700.014
cognitionGO:00508901410.014
positive regulation of response to stimulusGO:00485843230.014
cell maturationGO:00484691440.014
proteolysisGO:00065081920.014
purine nucleoside monophosphate catabolic processGO:0009128380.014
regionalizationGO:00030024160.014
positive regulation of programmed cell deathGO:0043068620.014
hematopoietic progenitor cell differentiationGO:000224410.014
nucleoside monophosphate catabolic processGO:0009125390.014
dna packagingGO:0006323910.014
positive regulation of molecular functionGO:00440931360.014
cell type specific apoptotic processGO:0097285380.013
negative regulation of programmed cell deathGO:0043069720.013
negative regulation of mitotic cell cycle phase transitionGO:19019911030.013
protein transportGO:00150311550.013
spindle assembly involved in mitosisGO:0090307500.013
taxisGO:00423303040.013
positive regulation of hydrolase activityGO:0051345780.013
regulation of cell cycle phase transitionGO:19019871300.013
positive regulation of apoptotic processGO:0043065470.013
histone deubiquitinationGO:001657880.013
positive regulation of proteolysisGO:0045862520.013
cellular macromolecule localizationGO:00707272200.013
spindle organizationGO:00070512530.013
histolysisGO:00075591020.013
mitotic g2 dna damage checkpointGO:0007095690.013
secretion by cellGO:00329401010.013
peptidyl lysine acetylationGO:0018394390.013
hindbrain developmentGO:003090220.013
olfactory learningGO:0008355560.013
production of sirna involved in rna interferenceGO:0030422110.012
epithelial cell developmentGO:00020642740.012
male mating behaviorGO:0060179700.012
organelle fusionGO:0048284460.012
sensory organ morphogenesisGO:00905962600.012
organic hydroxy compound metabolic processGO:1901615830.012
purine containing compound biosynthetic processGO:0072522300.012
regulation of endopeptidase activityGO:0052548360.012
response to temperature stimulusGO:00092661060.012
regulation of neurogenesisGO:00507671580.012
chromatin assembly or disassemblyGO:0006333520.012
cellular protein complex disassemblyGO:0043624350.012
positive regulation of cellular component organizationGO:00511301560.012
proteolysis involved in cellular protein catabolic processGO:0051603830.012
exocrine system developmentGO:00352721620.011
salivary gland cell autophagic cell deathGO:0035071830.011
spindle assemblyGO:0051225800.011
single organism cellular localizationGO:19025801800.011
salivary gland histolysisGO:0035070880.011
positive regulation of cell motilityGO:200014730.011
mitotic cell cycle phase transitionGO:00447721380.011
negative regulation of protein metabolic processGO:0051248850.011
sensory perception of mechanical stimulusGO:0050954720.011
protein catabolic processGO:00301631010.011
regulation of cyclin dependent protein serine threonine kinase activityGO:000007930.011
photoreceptor cell differentiationGO:00465301700.011
locomotory behaviorGO:00076261760.011
spermatogenesisGO:00072832000.011
positive regulation of transcription dna templatedGO:00458932660.010
positive regulation of rna metabolic processGO:00512542710.010
nuclear exportGO:0051168240.010
response to monosaccharideGO:003428440.010
lipid storageGO:0019915380.010
macromolecular complex disassemblyGO:0032984370.010
anterior posterior pattern specificationGO:00099521360.010
regulation of dna templated transcription in response to stressGO:004362040.010
embryonic organ developmentGO:0048568500.010

Sam-S disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.031
nervous system diseaseDOID:86300.026