IMP: Integrative Multi-species Prediction

Drosophila melanogaster

36 known processes

d4 (Dmel_CG2682)

CG2682 gene product from transcript CG2682-RB

(Aliases: CG2682,Dmel\CG2682,D4,dd4,Dd4)

FLYBASE: FBgn0033015
Entrez: 35485
UniProtKB: A1Z6E6
UniProtKB: Q0E9P4
UniProtKB: Q7K3G5

Process Predictions
Disease Predictions

d4 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

Filter by process size:

Biological process	GO term ID	Process size	Probability
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.230
regulation of phosphate metabolic process	GO:0019220	210	0.207
positive regulation of transcription dna templated	GO:0045893	266	0.199
regulation of mitotic cell cycle phase transition	GO:1901990	130	0.146
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.115
protein modification process	GO:0036211	438	0.106
cellular protein modification process	GO:0006464	438	0.091
regulation of phosphorus metabolic process	GO:0051174	210	0.089
meiotic cell cycle	GO:0051321	171	0.089
organelle assembly	GO:0070925	198	0.084
signal transduction by phosphorylation	GO:0023014	107	0.074
regulation of localization	GO:0032879	275	0.073
organelle fission	GO:0048285	340	0.064
transcription from rna polymerase ii promoter	GO:0006366	368	0.064
positive regulation of gene expression	GO:0010628	290	0.064
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.062
phosphorylation	GO:0016310	294	0.060
positive regulation of rna biosynthetic process	GO:1902680	266	0.060
regulation of intracellular signal transduction	GO:1902531	236	0.059
positive regulation of biosynthetic process	GO:0009891	316	0.055
positive regulation of signal transduction	GO:0009967	223	0.052
regionalization	GO:0003002	416	0.048
protein complex biogenesis	GO:0070271	201	0.048
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.046
intracellular signal transduction	GO:0035556	300	0.045
positive regulation of rna metabolic process	GO:0051254	271	0.045
dna integrity checkpoint	GO:0031570	81	0.044
neural precursor cell proliferation	GO:0061351	75	0.044
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.042
nuclear division	GO:0000280	332	0.041
positive regulation of cellular biosynthetic process	GO:0031328	316	0.040
regulation of phosphorylation	GO:0042325	147	0.039
positive regulation of macromolecule metabolic process	GO:0010604	405	0.036
regulation of protein localization	GO:0032880	76	0.035
reproductive structure development	GO:0048608	74	0.035
mapk cascade	GO:0000165	107	0.035
positive regulation of response to stimulus	GO:0048584	323	0.034
regulation of cell cycle phase transition	GO:1901987	130	0.033
endocytosis	GO:0006897	310	0.033
gonad development	GO:0008406	50	0.032
vesicle mediated transport	GO:0016192	381	0.031
histone lysine demethylation	GO:0070076	6	0.031
catabolic process	GO:0009056	409	0.031
negative regulation of cellular metabolic process	GO:0031324	382	0.030
sex differentiation	GO:0007548	81	0.030
positive regulation of signaling	GO:0023056	243	0.030
cellular response to dna damage stimulus	GO:0006974	223	0.030
negative regulation of signal transduction	GO:0009968	206	0.029
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.029
organic substance transport	GO:0071702	257	0.029
cell cycle phase transition	GO:0044770	140	0.028
cellular macromolecule catabolic process	GO:0044265	136	0.027
positive regulation of phosphorylation	GO:0042327	87	0.026
mitotic g2 dna damage checkpoint	GO:0007095	69	0.026
regulation of cell cycle	GO:0051726	291	0.025
cell proliferation	GO:0008283	299	0.025
stem cell proliferation	GO:0072089	88	0.024
dna damage checkpoint	GO:0000077	78	0.024
positive regulation of cellular component organization	GO:0051130	156	0.024
organic substance catabolic process	GO:1901575	308	0.024
organelle inheritance	GO:0048308	2	0.023
regulation of transport	GO:0051049	181	0.023
positive regulation of phosphorus metabolic process	GO:0010562	139	0.023
negative regulation of phosphorus metabolic process	GO:0010563	45	0.023
macromolecule catabolic process	GO:0009057	161	0.022
development of primary sexual characteristics	GO:0045137	50	0.022
intracellular transport	GO:0046907	228	0.022
adult behavior	GO:0030534	137	0.021
establishment of protein localization	GO:0045184	163	0.021
heterocycle catabolic process	GO:0046700	166	0.021
embryo development ending in birth or egg hatching	GO:0009792	152	0.021
chromosome segregation	GO:0007059	157	0.020
regulation of hemocyte proliferation	GO:0035206	37	0.020
response to abiotic stimulus	GO:0009628	341	0.020
positive regulation of cell communication	GO:0010647	250	0.020
g2 dna damage checkpoint	GO:0031572	69	0.019
negative regulation of mitotic cell cycle phase transition	GO:1901991	103	0.019
protein localization	GO:0008104	284	0.019
ras protein signal transduction	GO:0007265	88	0.019
negative regulation of cell cycle phase transition	GO:1901988	103	0.018
convergent extension	GO:0060026	2	0.018
regulation of multicellular organismal development	GO:2000026	414	0.018
appendage development	GO:0048736	401	0.018
maintenance of location	GO:0051235	73	0.018
positive regulation of phosphate metabolic process	GO:0045937	139	0.018
establishment of localization in cell	GO:0051649	402	0.017
defense response	GO:0006952	300	0.017
formation of a compartment boundary	GO:0060288	4	0.017
regulation of response to stress	GO:0080134	200	0.016
macromolecular complex assembly	GO:0065003	256	0.016
regulation of establishment of protein localization	GO:0070201	61	0.016
blastoderm segmentation	GO:0007350	159	0.015
reproductive system development	GO:0061458	74	0.015
diterpenoid biosynthetic process	GO:0016102	1	0.015
regulation of cell proliferation	GO:0042127	163	0.015
regulation of cellular component biogenesis	GO:0044087	201	0.015
segmentation	GO:0035282	207	0.015
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.015
extrinsic apoptotic signaling pathway	GO:0097191	1	0.015
regulation of cellular protein metabolic process	GO:0032268	243	0.015
response to wounding	GO:0009611	94	0.014
chromosome organization	GO:0051276	360	0.014
regulation of protein metabolic process	GO:0051246	256	0.014
regulation of translation	GO:0006417	56	0.014
cellular nitrogen compound catabolic process	GO:0044270	165	0.014
negative regulation of phosphate metabolic process	GO:0045936	45	0.014
regulation of ras protein signal transduction	GO:0046578	93	0.013
cilium assembly	GO:0042384	38	0.013
small gtpase mediated signal transduction	GO:0007264	88	0.013
mitotic dna damage checkpoint	GO:0044773	74	0.013
nucleobase containing compound catabolic process	GO:0034655	165	0.013
regulation of molecular function	GO:0065009	217	0.013
secretion by cell	GO:0032940	101	0.013
multicellular organismal aging	GO:0010259	140	0.013
response to biotic stimulus	GO:0009607	294	0.013
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.012
epithelial cell differentiation	GO:0030855	322	0.012
negative regulation of cellular biosynthetic process	GO:0031327	277	0.012
nitric oxide metabolic process	GO:0046209	1	0.012
actin cytoskeleton organization	GO:0030036	206	0.012
cell maturation	GO:0048469	144	0.012
homeostatic process	GO:0042592	199	0.012
negative regulation of protein metabolic process	GO:0051248	85	0.012
reactive nitrogen species metabolic process	GO:2001057	0	0.012
morphogenesis of an epithelium	GO:0002009	276	0.012
mrna metabolic process	GO:0016071	124	0.012
gland development	GO:0048732	191	0.012
mitotic dna integrity checkpoint	GO:0044774	75	0.012
defense response to other organism	GO:0098542	225	0.011
neuroblast proliferation	GO:0007405	74	0.011
phagocytosis	GO:0006909	215	0.011
protein targeting	GO:0006605	64	0.011
positive regulation of neuron projection regeneration	GO:0070572	3	0.011
aromatic compound catabolic process	GO:0019439	166	0.011
anterior posterior axis specification	GO:0009948	109	0.011
death	GO:0016265	284	0.011
cellular catabolic process	GO:0044248	372	0.011
cilium morphogenesis	GO:0060271	39	0.011
chromatin modification	GO:0016568	147	0.011
mitotic nuclear division	GO:0007067	213	0.011
mitochondrial membrane organization	GO:0007006	3	0.011
negative regulation of response to stimulus	GO:0048585	258	0.011
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	119	0.011
regulation of cell cycle process	GO:0010564	181	0.011
regulation of secretion by cell	GO:1903530	39	0.010
sister chromatid segregation	GO:0000819	92	0.010
cell cycle checkpoint	GO:0000075	95	0.010
regulation of erk1 and erk2 cascade	GO:0070372	39	0.010
appendage morphogenesis	GO:0035107	397	0.010
single organism intracellular transport	GO:1902582	207	0.010
negative regulation of protein binding	GO:0032091	1	0.010
negative regulation of cell death	GO:0060548	81	0.010

d4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	disease of anatomical entity	DOID:7	0	0.030

Loading network...

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network