IMP: Integrative Multi-species Prediction

Drosophila melanogaster

207 known processes

lwr (Dmel_CG3018)

lesswright

(Aliases: ubc9,Lwr,dip4,dUBC9,l(2)05487,l(2)05486,UBC9,Ubc 9,Dmubc9,CG3018,Dmel\CG3018,FBgn0010602,l(2)01519,dUbc9,Ubc9,DmUbc9,i56,hbl,semi,Ubc-9,DUbc9,i105,l(2)02858)

Entrez: 33226
FLYBASE: FBgn0010602
UniProtKB: Q7KNM2

Process Predictions
Disease Predictions

lwr biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
embryo development ending in birth or egg hatching	GO:0009792	152	0.989
negative regulation of cellular metabolic process	GO:0031324	382	0.988	Human Mouse Worm
negative regulation of cellular biosynthetic process	GO:0031327	277	0.987	Human Mouse Worm
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.981	Human Mouse Worm
positive regulation of cellular biosynthetic process	GO:0031328	316	0.974
positive regulation of rna metabolic process	GO:0051254	271	0.968
negative regulation of transcription dna templated	GO:0045892	237	0.966	Human Mouse Worm
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.961	Human Mouse Worm
chromosome organization	GO:0051276	360	0.953
positive regulation of macromolecule metabolic process	GO:0010604	405	0.946
protein modification process	GO:0036211	438	0.944
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.938	Human Mouse Worm
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.937
positive regulation of transcription dna templated	GO:0045893	266	0.908
immune system process	GO:0002376	347	0.906
chromatin organization	GO:0006325	207	0.874
chromatin modification	GO:0016568	147	0.847
positive regulation of gene expression	GO:0010628	290	0.845
negative regulation of biosynthetic process	GO:0009890	277	0.839	Human Mouse Worm
positive regulation of rna biosynthetic process	GO:1902680	266	0.829
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.826
negative regulation of gene expression	GO:0010629	387	0.800	Human Mouse Worm
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	119	0.775	Human Mouse Worm
cellular protein modification process	GO:0006464	438	0.769
response to external biotic stimulus	GO:0043207	293	0.742
transcription from rna polymerase ii promoter	GO:0006366	368	0.741	Human Mouse Worm
positive regulation of cellular protein metabolic process	GO:0032270	118	0.736
defense response to other organism	GO:0098542	225	0.731
cellular macromolecular complex assembly	GO:0034622	153	0.728
regulation of gene expression epigenetic	GO:0040029	128	0.720
negative regulation of rna biosynthetic process	GO:1902679	240	0.683	Human Mouse Worm
axonogenesis	GO:0007409	290	0.664
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.661	Human Mouse Worm
positive regulation of biosynthetic process	GO:0009891	316	0.649
multicellular organismal reproductive behavior	GO:0033057	110	0.646	Worm
covalent chromatin modification	GO:0016569	106	0.623
camera type eye development	GO:0043010	4	0.615
apoptotic process	GO:0006915	159	0.596	Worm
taxis	GO:0042330	304	0.587
negative regulation of signaling	GO:0023057	219	0.568
posttranscriptional gene silencing by rna	GO:0035194	45	0.544
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.542	Human Mouse Worm
histone modification	GO:0016570	106	0.537
regulation of multi organism process	GO:0043900	131	0.528
regulation of response to stress	GO:0080134	200	0.511
rna interference	GO:0016246	27	0.510
cell death	GO:0008219	279	0.504	Worm
protein complex assembly	GO:0006461	200	0.501
negative regulation of rna metabolic process	GO:0051253	251	0.489	Human Mouse Worm
chemotaxis	GO:0006935	249	0.476
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.473
regulation of apoptotic process	GO:0042981	130	0.471
cellular response to organic substance	GO:0071310	132	0.464
positive regulation of multi organism process	GO:0043902	40	0.459
death	GO:0016265	284	0.456	Worm
macromolecular complex assembly	GO:0065003	256	0.455
regionalization	GO:0003002	416	0.451
appendage development	GO:0048736	401	0.449
immune response	GO:0006955	246	0.431
meiotic nuclear division	GO:0007126	151	0.427
positive regulation of protein metabolic process	GO:0051247	128	0.421
protein acetylation	GO:0006473	39	0.407
negative regulation of mitotic cell cycle phase transition	GO:1901991	103	0.404
posttranscriptional regulation of gene expression	GO:0010608	145	0.396
neuron projection guidance	GO:0097485	241	0.382
negative regulation of gene expression epigenetic	GO:0045814	77	0.381
embryonic pattern specification	GO:0009880	174	0.380
cellular component assembly involved in morphogenesis	GO:0010927	151	0.370
intracellular transport	GO:0046907	228	0.368
chromatin assembly	GO:0031497	48	0.357
regulation of cellular component biogenesis	GO:0044087	201	0.355
eye development	GO:0001654	323	0.354
negative regulation of signal transduction	GO:0009968	206	0.343
dna conformation change	GO:0071103	105	0.337
regulation of protein metabolic process	GO:0051246	256	0.325
methylation	GO:0032259	47	0.314
vesicle mediated transport	GO:0016192	381	0.307
blastoderm segmentation	GO:0007350	159	0.306
dna packaging	GO:0006323	91	0.299
response to biotic stimulus	GO:0009607	294	0.297
histone acetylation	GO:0016573	38	0.296
reproductive structure development	GO:0048608	74	0.286	Worm
negative regulation of cell communication	GO:0010648	223	0.286
cell maturation	GO:0048469	144	0.283
striated muscle cell differentiation	GO:0051146	90	0.268
endocytosis	GO:0006897	310	0.265
negative regulation of apoptotic process	GO:0043066	63	0.264
regulation of response to gamma radiation	GO:2001228	4	0.256
posttranscriptional gene silencing	GO:0016441	46	0.255
dendrite development	GO:0016358	204	0.253
regulation of immune response	GO:0050776	118	0.249
protein dna complex subunit organization	GO:0071824	86	0.245
regulation of cell death	GO:0010941	173	0.245
gonad development	GO:0008406	50	0.245	Worm
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.235
phagocytosis	GO:0006909	215	0.233
regulation of defense response	GO:0031347	102	0.225
body morphogenesis	GO:0010171	2	0.222
dendrite morphogenesis	GO:0048813	199	0.222
intracellular receptor signaling pathway	GO:0030522	19	0.216	Rat
gene silencing by rna	GO:0031047	57	0.215
defense response	GO:0006952	300	0.213
axon development	GO:0061564	297	0.211
pole plasm assembly	GO:0007315	61	0.209
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.206	Human Mouse Worm
protein complex biogenesis	GO:0070271	201	0.205
striated muscle cell development	GO:0055002	50	0.196
dna metabolic process	GO:0006259	227	0.195
segmentation	GO:0035282	207	0.191
purine ribonucleoside triphosphate catabolic process	GO:0009207	108	0.191
negative regulation of cell differentiation	GO:0045596	143	0.188
regulation of molecular function	GO:0065009	217	0.183	Rat
chromatin silencing	GO:0006342	76	0.176
response to bacterium	GO:0009617	198	0.175
muscle cell development	GO:0055001	50	0.174
immune effector process	GO:0002252	98	0.165
dna integrity checkpoint	GO:0031570	81	0.161
internal peptidyl lysine acetylation	GO:0018393	38	0.158
regulation of immune system process	GO:0002682	176	0.155
cellular response to chemical stimulus	GO:0070887	199	0.143
response to other organism	GO:0051707	293	0.142
oviposition	GO:0018991	19	0.133	Worm
nuclear division	GO:0000280	332	0.131
response to light stimulus	GO:0009416	124	0.129
regulation of cellular catabolic process	GO:0031329	157	0.128
regulation of cell proliferation	GO:0042127	163	0.128
cell cycle phase transition	GO:0044770	140	0.128
negative regulation of response to stimulus	GO:0048585	258	0.127
retina development in camera type eye	GO:0060041	4	0.122
reproductive behavior	GO:0019098	122	0.121	Worm
peptidyl amino acid modification	GO:0018193	105	0.118
positive regulation of phosphate metabolic process	GO:0045937	139	0.116
multi multicellular organism process	GO:0044706	123	0.115	Worm
camera type eye morphogenesis	GO:0048593	2	0.113
regulation of intracellular signal transduction	GO:1902531	236	0.111	Mouse
sensory organ morphogenesis	GO:0090596	260	0.108
regulation of transport	GO:0051049	181	0.107
innate immune response	GO:0045087	144	0.106
dendrite guidance	GO:0070983	21	0.106
muscle structure development	GO:0061061	224	0.102	Worm
cellular protein complex assembly	GO:0043623	71	0.100
molting cycle process	GO:0022404	29	0.100
positive regulation of molecular function	GO:0044093	136	0.099	Rat
small molecule metabolic process	GO:0044281	305	0.099
interspecies interaction between organisms	GO:0044419	16	0.096
g2 dna damage checkpoint	GO:0031572	69	0.096
genitalia development	GO:0048806	26	0.096	Worm
mitotic spindle organization	GO:0007052	220	0.095	Yeast
multi organism behavior	GO:0051705	175	0.093	Worm
cell migration	GO:0016477	238	0.092
protein localization	GO:0008104	284	0.092
regulation of proteolysis	GO:0030162	87	0.091
nuclear transcribed mrna catabolic process	GO:0000956	24	0.091
regulation of cellular protein metabolic process	GO:0032268	243	0.091
dna damage checkpoint	GO:0000077	78	0.090
organic hydroxy compound metabolic process	GO:1901615	83	0.090
mitotic g2 dna damage checkpoint	GO:0007095	69	0.090
regulation of localization	GO:0032879	275	0.089	Worm
regulation of cell cycle	GO:0051726	291	0.088
gland development	GO:0048732	191	0.087
negative regulation of programmed cell death	GO:0043069	72	0.086
transcription initiation from rna polymerase ii promoter	GO:0006367	25	0.085
peptidyl lysine acetylation	GO:0018394	39	0.085
organelle fission	GO:0048285	340	0.085
heterocycle catabolic process	GO:0046700	166	0.084
molting cycle chitin based cuticle	GO:0007591	56	0.084
internal protein amino acid acetylation	GO:0006475	38	0.083
mitotic dna integrity checkpoint	GO:0044774	75	0.083
mitotic g2 m transition checkpoint	GO:0044818	70	0.083
transcription elongation from rna polymerase ii promoter	GO:0006368	18	0.082
negative regulation of cellular component organization	GO:0051129	108	0.081
dorsal ventral pattern formation	GO:0009953	133	0.077
male gamete generation	GO:0048232	201	0.077
development of primary sexual characteristics	GO:0045137	50	0.074	Worm
humoral immune response	GO:0006959	117	0.073
developmental maturation	GO:0021700	172	0.071
gene silencing	GO:0016458	138	0.070
spermatogenesis	GO:0007283	200	0.070
columnar cuboidal epithelial cell differentiation	GO:0002065	256	0.068
dna templated transcription elongation	GO:0006354	18	0.068
positive regulation of response to stimulus	GO:0048584	323	0.067	Mouse Rat
regulation of response to external stimulus	GO:0032101	115	0.066
pole plasm mrna localization	GO:0019094	49	0.066
positive regulation of programmed cell death	GO:0043068	62	0.065
protein modification by small protein conjugation or removal	GO:0070647	106	0.065
regulation of immune effector process	GO:0002697	52	0.065
sex differentiation	GO:0007548	81	0.064	Worm
positive regulation of proteolysis	GO:0045862	52	0.063
regulation of catalytic activity	GO:0050790	185	0.063
muscle cell differentiation	GO:0042692	103	0.062
central nervous system development	GO:0007417	201	0.060
response to heat	GO:0009408	63	0.059
regulation of response to biotic stimulus	GO:0002831	63	0.059
actin cytoskeleton organization	GO:0030036	206	0.059
peptidyl lysine modification	GO:0018205	57	0.057
pole plasm rna localization	GO:0007316	52	0.057
regulation of innate immune response	GO:0045088	71	0.057
telencephalon development	GO:0021537	2	0.056
pole plasm oskar mrna localization	GO:0045451	46	0.055
positive regulation of ribosome biogenesis	GO:0090070	3	0.054
cellular macromolecule localization	GO:0070727	220	0.053
nuclear transport	GO:0051169	72	0.052
regulation of cellular response to stress	GO:0080135	89	0.052
negative regulation of cell cycle phase transition	GO:1901988	103	0.051
nucleocytoplasmic transport	GO:0006913	72	0.051
determination of dorsal ventral asymmetry	GO:0048262	3	0.051
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.051
proteasome mediated ubiquitin dependent protein catabolic process	GO:0043161	54	0.051	Rat
positive regulation of protein modification process	GO:0031401	58	0.050
cellular amino acid metabolic process	GO:0006520	61	0.050
negative regulation of cell cycle process	GO:0010948	109	0.048
negative regulation of purine nucleotide catabolic process	GO:0033122	1	0.048
heart development	GO:0007507	82	0.048
positive regulation of cellular component biogenesis	GO:0044089	80	0.048
regulation of mitotic cell cycle phase transition	GO:1901990	130	0.048
programmed cell death	GO:0012501	257	0.047	Worm
defense response to bacterium	GO:0042742	178	0.046
negative regulation of cell cycle	GO:0045786	116	0.046
regulation of catabolic process	GO:0009894	170	0.046
embryonic morphogenesis	GO:0048598	206	0.046
regulation of cellular localization	GO:0060341	136	0.045
actin filament based process	GO:0030029	220	0.044
embryonic organ development	GO:0048568	50	0.044
cell proliferation	GO:0008283	299	0.043
single organism cellular localization	GO:1902580	180	0.043
regulation of programmed cell death	GO:0043067	152	0.042
larval development	GO:0002164	104	0.042
mitotic cell cycle checkpoint	GO:0007093	88	0.041
regulation of gene silencing	GO:0060968	63	0.041
protein phosphorylation	GO:0006468	169	0.041
lipid localization	GO:0010876	54	0.040
anterior posterior axis specification	GO:0009948	109	0.040
oocyte development	GO:0048599	124	0.040
eye morphogenesis	GO:0048592	260	0.040
regulation of production of molecular mediator of immune response	GO:0002700	44	0.040
organic substance transport	GO:0071702	257	0.039
response to radiation	GO:0009314	155	0.038
regulation of protein modification process	GO:0031399	112	0.038
positive regulation of cell proliferation	GO:0008284	47	0.038
organelle inheritance	GO:0048308	2	0.037
regulation of intracellular transport	GO:0032386	64	0.037
wing disc morphogenesis	GO:0007472	344	0.037
embryonic axis specification	GO:0000578	107	0.036
negative regulation of nucleoside metabolic process	GO:0045978	1	0.036
anterior posterior axis specification embryo	GO:0008595	103	0.036
organonitrogen compound metabolic process	GO:1901564	318	0.036
reproductive system development	GO:0061458	74	0.035	Worm
meiotic cell cycle	GO:0051321	171	0.035
post embryonic appendage morphogenesis	GO:0035120	385	0.035
cellular response to organic cyclic compound	GO:0071407	32	0.035
ribonucleoprotein complex subunit organization	GO:0071826	28	0.035
axis specification	GO:0009798	167	0.034
nitrogen compound transport	GO:0071705	85	0.034
multi organism reproductive behavior	GO:0044705	121	0.034	Worm
axon guidance	GO:0007411	233	0.034
macromolecule methylation	GO:0043414	45	0.034
oocyte anterior posterior axis specification	GO:0007314	72	0.034
appendage morphogenesis	GO:0035107	397	0.033
molting cycle	GO:0042303	56	0.033
positive regulation of growth	GO:0045927	75	0.033
regulation of symbiosis encompassing mutualism through parasitism	GO:0043903	15	0.033
positive regulation of intracellular signal transduction	GO:1902533	116	0.032	Mouse
photoreceptor cell differentiation	GO:0046530	170	0.032
regulation of i kappab kinase nf kappab signaling	GO:0043122	2	0.032	Mouse
defense response to virus	GO:0051607	23	0.031
histone h2a acetylation	GO:0043968	1	0.031
establishment of localization in cell	GO:0051649	402	0.031
chromatin assembly or disassembly	GO:0006333	52	0.031
mrna metabolic process	GO:0016071	124	0.031
organelle assembly	GO:0070925	198	0.031
single organism nuclear import	GO:1902593	51	0.030
regulation of meiosis	GO:0040020	3	0.030
negative regulation of cell proliferation	GO:0008285	69	0.029
ribonucleoprotein complex biogenesis	GO:0022613	31	0.029
positive regulation of catabolic process	GO:0009896	105	0.029
maternal determination of anterior posterior axis embryo	GO:0008358	74	0.028
retina morphogenesis in camera type eye	GO:0060042	2	0.028
organic cyclic compound catabolic process	GO:1901361	168	0.027
cellular macromolecule catabolic process	GO:0044265	136	0.027	Rat
myofibril assembly	GO:0030239	36	0.027
protein alkylation	GO:0008213	43	0.027
receptor mediated endocytosis	GO:0006898	21	0.026
protein acylation	GO:0043543	42	0.026
negative regulation of cell death	GO:0060548	81	0.026
compound eye development	GO:0048749	307	0.025
protein transport	GO:0015031	155	0.025
stem cell differentiation	GO:0048863	117	0.025
cellular protein localization	GO:0034613	160	0.025
regulation of dna templated transcription elongation	GO:0032784	17	0.025
dna templated transcription initiation	GO:0006352	25	0.024
intracellular signal transduction	GO:0035556	300	0.024	Mouse
intracellular mrna localization	GO:0008298	66	0.024
neural retina development	GO:0003407	4	0.023
negative regulation of immune system process	GO:0002683	50	0.023
oocyte morphogenesis	GO:0048601	3	0.023
negative regulation of organelle organization	GO:0010639	56	0.023
dendrite regeneration	GO:0031104	2	0.023
compound eye photoreceptor cell differentiation	GO:0001751	140	0.023
positive regulation of signal transduction	GO:0009967	223	0.023	Mouse Rat
response to lipid	GO:0033993	38	0.023
cellular response to lipid	GO:0071396	20	0.023
cellular catabolic process	GO:0044248	372	0.023	Rat
mitotic sister chromatid segregation	GO:0000070	87	0.022
tube development	GO:0035295	244	0.022	Worm
regulation of striated muscle contraction	GO:0006942	2	0.022
positive regulation of phosphorus metabolic process	GO:0010562	139	0.022
zygotic specification of dorsal ventral axis	GO:0007352	3	0.022
histone h4 acetylation	GO:0043967	13	0.022
negative regulation of protein metabolic process	GO:0051248	85	0.021
localization of cell	GO:0051674	257	0.021
maternal determination of dorsal ventral axis ovarian follicular epithelium soma encoded	GO:0008071	1	0.021
organic substance catabolic process	GO:1901575	308	0.021	Rat
regulation of planar cell polarity pathway involved in axis elongation	GO:2000040	2	0.020
cytoplasmic transport	GO:0016482	130	0.020
regulation of phosphorylation	GO:0042325	147	0.020
membrane organization	GO:0061024	112	0.019
chromosome condensation	GO:0030261	41	0.019
cellular response to dna damage stimulus	GO:0006974	223	0.019
response to organic cyclic compound	GO:0014070	89	0.019
defense response to gram negative bacterium	GO:0050829	94	0.019
positive regulation of cell maturation	GO:1903431	2	0.019
cellular component disassembly	GO:0022411	46	0.018
exocrine system development	GO:0035272	162	0.018
regulation of hydrolase activity	GO:0051336	97	0.018
negative regulation of gtp catabolic process	GO:0033125	1	0.018
regulation of ras protein signal transduction	GO:0046578	93	0.018
growth	GO:0040007	359	0.018
intracellular mrna localization involved in pattern specification process	GO:0060810	56	0.018
regulation of heterochromatin assembly	GO:0031445	8	0.018
phospholipid transport	GO:0015914	2	0.018
regulation of mitotic cell cycle	GO:0007346	190	0.018
nucleoside phosphate catabolic process	GO:1901292	110	0.017
regulation of ruffle assembly	GO:1900027	1	0.017
response to organic substance	GO:0010033	284	0.017
glycosyl compound metabolic process	GO:1901657	127	0.017
cell motility	GO:0048870	251	0.017
chromatin remodeling	GO:0006338	72	0.017
guanosine containing compound catabolic process	GO:1901069	74	0.017
establishment of protein localization	GO:0045184	163	0.017
mitochondrion organization	GO:0007005	65	0.016
synapse organization	GO:0050808	196	0.016
response to oxygen containing compound	GO:1901700	200	0.016
actomyosin structure organization	GO:0031032	56	0.016
intracellular mrna localization involved in anterior posterior axis specification	GO:0060811	53	0.016
amine metabolic process	GO:0009308	12	0.016
positive regulation of immune response	GO:0050778	63	0.016
regulation of phosphate metabolic process	GO:0019220	210	0.016
positive regulation of catalytic activity	GO:0043085	118	0.016
modification dependent macromolecule catabolic process	GO:0043632	79	0.015	Rat
pigment metabolic process	GO:0042440	84	0.015
purine nucleoside triphosphate catabolic process	GO:0009146	108	0.015
production of small rna involved in gene silencing by rna	GO:0070918	15	0.015
regulation of hemocyte proliferation	GO:0035206	37	0.015
oocyte microtubule cytoskeleton polarization	GO:0008103	22	0.015
meiotic nuclear envelope disassembly	GO:0051078	2	0.015
imaginal disc derived appendage development	GO:0048737	399	0.015
histone methylation	GO:0016571	40	0.014
regulation of cellular amine metabolic process	GO:0033238	3	0.014
symbiosis encompassing mutualism through parasitism	GO:0044403	16	0.014
regulation of cell proliferation involved in compound eye morphogenesis	GO:2000495	2	0.014
positive regulation of phosphorylation	GO:0042327	87	0.014
protein import	GO:0017038	55	0.014
oocyte fate commitment	GO:0048600	2	0.014
positive regulation of defense response	GO:0031349	59	0.014
regulation of sequence specific dna binding transcription factor activity	GO:0051090	12	0.014	Rat
lateral inhibition	GO:0046331	206	0.014
positive regulation of cell communication	GO:0010647	250	0.013	Mouse Rat
regulation of nucleotide metabolic process	GO:0006140	62	0.013
imaginal disc derived wing expansion	GO:0048526	7	0.013
antimicrobial humoral response	GO:0019730	99	0.013
positive regulation of cellular catabolic process	GO:0031331	95	0.013
purine ribonucleotide catabolic process	GO:0009154	109	0.013
negative regulation of developmental growth	GO:0048640	64	0.013
regulation of cell cycle process	GO:0010564	181	0.012
border follicle cell delamination	GO:0030709	3	0.012
anatomical structure homeostasis	GO:0060249	97	0.012
i kappab kinase nf kappab signaling	GO:0007249	6	0.012	Mouse
negative regulation of nucleotide catabolic process	GO:0030812	1	0.012
oocyte construction	GO:0007308	112	0.012
response to extracellular stimulus	GO:0009991	116	0.012
meiotic spindle checkpoint	GO:0044779	1	0.012
dorsal vessel heart proper cell fate commitment	GO:0035053	2	0.012
regeneration	GO:0031099	16	0.012
phosphorylation	GO:0016310	294	0.012
tissue death	GO:0016271	102	0.012
cellular amide metabolic process	GO:0043603	80	0.011
negative regulation of terminal cell fate specification open tracheal system	GO:0035155	2	0.011
regulation of system process	GO:0044057	36	0.011
nitric oxide metabolic process	GO:0046209	1	0.011
specification of segmental identity antennal segment	GO:0007383	2	0.011
oocyte differentiation	GO:0009994	145	0.011
carboxylic acid metabolic process	GO:0019752	92	0.011
tripartite regional subdivision	GO:0007351	103	0.011
oocyte axis specification	GO:0007309	108	0.011
ribonucleotide catabolic process	GO:0009261	109	0.011
regulation of ral gtpase activity	GO:0032315	1	0.011
regulation of cdc42 protein signal transduction	GO:0032489	3	0.011
post embryonic hemopoiesis	GO:0035166	17	0.011
regulation of cell cycle phase transition	GO:1901987	130	0.011
dna integration	GO:0015074	1	0.011
regulation of growth	GO:0040008	233	0.011
regulation of protein stability	GO:0031647	43	0.011
tricarboxylic acid metabolic process	GO:0072350	1	0.011
regulation of humoral immune response	GO:0002920	51	0.011
nucleoside triphosphate metabolic process	GO:0009141	120	0.011
negative regulation of multicellular organismal process	GO:0051241	142	0.011
regulation of endocrine process	GO:0044060	2	0.011
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.010
respiratory system development	GO:0060541	213	0.010
histone lysine methylation	GO:0034968	32	0.010
mitotic dna damage checkpoint	GO:0044773	74	0.010
regulation of dna metabolic process	GO:0051052	34	0.010
negative regulation of dna templated transcription initiation	GO:2000143	1	0.010

lwr disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
spinocerebellar degeneration	DOID:2478	0.018
disease of anatomical entity	DOID:7	0.018
central nervous system disease	DOID:331	0.018
spinocerebellar ataxia	DOID:1441	0.018
neurodegenerative disease	DOID:1289	0.018
nervous system disease	DOID:863	0.018
syndrome	DOID:225	0.011

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