Drosophila melanogaster

30 known processes

Pgk (Dmel_CG3127)

Phosphoglycerate kinase

(Aliases: pgk,CG3127,l(2)23AB3,PGK,Dmel\CG3127,ESTS:169C9S,l(2)23Ac,169C9S,anon-sts18)

Pgk biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
synaptic transmissionGO:00072682880.925
generation of precursor metabolites and energyGO:0006091420.876
oxidation reduction processGO:00551141230.846
nad metabolic processGO:001967410.780
synapse organizationGO:00508081960.748
establishment of localization in cellGO:00516494020.745
carbohydrate catabolic processGO:001605270.641
transmembrane transportGO:00550851390.618
mitochondrion organizationGO:0007005650.613
single organism biosynthetic processGO:00447112060.586
organic acid metabolic processGO:00060821030.529
organonitrogen compound metabolic processGO:19015643180.480
pyruvate metabolic processGO:000609070.452
carbohydrate metabolic processGO:0005975820.445
single organism carbohydrate metabolic processGO:0044723720.415
myotube differentiationGO:0014902460.405
striated muscle cell differentiationGO:0051146900.394
ion transportGO:00068111450.390
energy derivation by oxidation of organic compoundsGO:0015980320.388
carbohydrate biosynthetic processGO:0016051170.382
oxoacid metabolic processGO:00434361030.381
secretion by cellGO:00329401010.380
carboxylic acid metabolic processGO:0019752920.349
ribonucleoside biosynthetic processGO:004245530.342
single organism carbohydrate catabolic processGO:004472470.332
actomyosin structure organizationGO:0031032560.330
enzyme linked receptor protein signaling pathwayGO:00071671790.313
glycolytic processGO:000609660.310
muscle cell differentiationGO:00426921030.306
nucleoside metabolic processGO:00091161270.301
myoblast fusionGO:0007520430.282
cellular component assembly involved in morphogenesisGO:00109271510.266
cellular response to chemical stimulusGO:00708871990.265
negative regulation of signalingGO:00230572190.262
lipid localizationGO:0010876540.253
cation transmembrane transportGO:0098655880.241
nicotinamide nucleotide metabolic processGO:004649620.238
cellular amino acid metabolic processGO:0006520610.236
neuron neuron synaptic transmissionGO:0007270140.225
organophosphate metabolic processGO:00196371950.221
negative regulation of response to stimulusGO:00485852580.209
syncytium formationGO:0006949430.198
regulation of localizationGO:00328792750.196
homeostatic processGO:00425921990.189
syncytium formation by plasma membrane fusionGO:0000768430.186
muscle structure developmentGO:00610612240.183
atp biosynthetic processGO:000675420.183
cellular response to reactive oxygen speciesGO:0034614140.179
defense responseGO:00069523000.175
small molecule metabolic processGO:00442813050.174
secretionGO:00469031090.174
monocarboxylic acid metabolic processGO:0032787290.169
programmed cell deathGO:00125012570.165
regulation of transportGO:00510491810.164
cellular lipid metabolic processGO:0044255830.157
oxidoreduction coenzyme metabolic processGO:000673320.155
regulation of synaptic transmissionGO:0050804690.150
ion transmembrane transportGO:00342201220.148
signal releaseGO:0023061490.144
organic substance catabolic processGO:19015753080.143
response to organic substanceGO:00100332840.142
single organism catabolic processGO:00447122280.138
catabolic processGO:00090564090.138
lipid storageGO:0019915380.137
synapse assemblyGO:00074161430.134
negative regulation of protein metabolic processGO:0051248850.134
cellular ketone metabolic processGO:0042180240.132
inorganic cation transmembrane transportGO:0098662610.129
response to oxygen containing compoundGO:19017002000.125
protein complex assemblyGO:00064612000.122
appendage morphogenesisGO:00351073970.120
metal ion transportGO:0030001740.113
cellular macromolecular complex assemblyGO:00346221530.110
regulation of cellular localizationGO:00603411360.110
purine nucleoside metabolic processGO:00422781270.107
neurotransmitter transportGO:0006836370.104
regulation of response to stressGO:00801342000.099
negative regulation of signal transductionGO:00099682060.098
pyridine containing compound metabolic processGO:007252430.097
response to organonitrogen compoundGO:0010243750.095
single organism membrane organizationGO:0044802930.094
cellular protein modification processGO:00064644380.094
cellular protein complex assemblyGO:0043623710.091
regulation of cell deathGO:00109411730.091
cellular respirationGO:0045333260.088
purine nucleoside biosynthetic processGO:004245130.087
posttranscriptional regulation of gene expressionGO:00106081450.086
nucleotide metabolic processGO:00091171610.085
negative regulation of cell communicationGO:00106482230.084
response to abiotic stimulusGO:00096283410.084
neuromuscular synaptic transmissionGO:0007274670.083
protein localizationGO:00081042840.083
lipid metabolic processGO:00066291210.083
hexose metabolic processGO:001931880.082
response to glucoseGO:000974920.082
locomotory behaviorGO:00076261760.081
somatic muscle developmentGO:0007525660.080
cation transportGO:00068121100.080
deathGO:00162652840.077
cellular polysaccharide metabolic processGO:0044264110.077
g protein coupled receptor signaling pathwayGO:00071861360.076
atp metabolic processGO:0046034490.074
lipid catabolic processGO:0016042210.073
regulation of secretion by cellGO:1903530390.073
cell deathGO:00082192790.073
phosphorylationGO:00163102940.070
membrane organizationGO:00610241120.069
response to monosaccharideGO:003428440.068
agingGO:00075681430.068
ribonucleoside triphosphate biosynthetic processGO:000920120.067
synaptic transmission glutamatergicGO:003524970.067
regulation of membrane potentialGO:0042391350.067
myofibril assemblyGO:0030239360.065
actin filament based processGO:00300292200.063
purine ribonucleoside metabolic processGO:00461281270.062
glucose metabolic processGO:000600650.062
positive regulation of cell communicationGO:00106472500.061
response to mechanical stimulusGO:0009612280.061
regulation of secretionGO:0051046440.061
regulation of programmed cell deathGO:00430671520.059
polysaccharide metabolic processGO:0005976110.059
myosin filament organizationGO:003103350.058
negative regulation of cellular protein metabolic processGO:0032269850.057
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178650.055
response to extracellular stimulusGO:00099911160.052
neurotransmitter secretionGO:0007269350.052
response to oxidative stressGO:0006979860.050
regulation of mitochondrion organizationGO:0010821120.050
inorganic ion transmembrane transportGO:0098660730.049
regulation of neurotransmitter levelsGO:0001505380.046
response to endogenous stimulusGO:00097191190.046
purine nucleotide biosynthetic processGO:0006164290.045
response to temperature stimulusGO:00092661060.045
response to nitrogen compoundGO:1901698900.045
oxidative phosphorylationGO:000611990.044
actin cytoskeleton organizationGO:00300362060.044
neuron deathGO:0070997270.043
cellular carbohydrate metabolic processGO:0044262220.042
organelle assemblyGO:00709251980.042
positive regulation of signalingGO:00230562430.042
adult behaviorGO:00305341370.041
ribonucleoside triphosphate metabolic processGO:00091991190.041
translationGO:0006412690.041
purine containing compound metabolic processGO:00725211550.041
striated muscle myosin thick filament assemblyGO:007168830.040
regulation of response to oxidative stressGO:190288240.039
adult locomotory behaviorGO:0008344760.038
regulation of cellular component biogenesisGO:00440872010.038
glucan biosynthetic processGO:000925020.038
nucleoside biosynthetic processGO:000916330.037
regulation of ion transportGO:0043269390.037
monosaccharide metabolic processGO:000599690.037
regulation of developmental growthGO:00486381740.037
glycosyl compound metabolic processGO:19016571270.036
macromolecular complex assemblyGO:00650032560.036
response to organic cyclic compoundGO:0014070890.035
mechanosensory behaviorGO:0007638120.035
regulation of protein metabolic processGO:00512462560.035
lipid modificationGO:0030258240.035
nucleobase containing small molecule metabolic processGO:00550861740.035
response to peptide hormoneGO:0043434290.034
regulation of neurotransmitter secretionGO:0046928140.034
neurological system processGO:00508773580.033
cellular macromolecule localizationGO:00707272200.032
male gamete generationGO:00482322010.031
carbohydrate derivative metabolic processGO:19011352170.031
potassium ion transportGO:0006813200.031
regulation of catalytic activityGO:00507901850.031
purine ribonucleoside monophosphate biosynthetic processGO:000916830.031
protein complex biogenesisGO:00702712010.030
cellular response to growth factor stimulusGO:0071363300.030
organonitrogen compound biosynthetic processGO:19015661170.029
regulation of cellular amine metabolic processGO:003323830.029
single organism behaviorGO:00447083910.028
regulation of cellular protein metabolic processGO:00322682430.028
striated muscle cell developmentGO:0055002500.028
response to reactive oxygen speciesGO:0000302240.028
regulation of apoptotic processGO:00429811300.028
columnar cuboidal epithelial cell developmentGO:00020662490.027
maintenance of locationGO:0051235730.027
establishment of protein localizationGO:00451841630.027
response to organophosphorusGO:004668320.026
protein phosphorylationGO:00064681690.026
eggshell chorion assemblyGO:0007306660.026
purine nucleoside triphosphate metabolic processGO:00091441190.026
camera type eye developmentGO:004301040.025
negative regulation of organelle organizationGO:0010639560.025
positive regulation of macromolecule metabolic processGO:00106044050.025
negative regulation of multicellular organismal processGO:00512411420.025
innate immune responseGO:00450871440.024
purine nucleoside monophosphate biosynthetic processGO:000912730.024
axon guidanceGO:00074112330.024
determination of adult lifespanGO:00083401370.024
polysaccharide biosynthetic processGO:000027170.023
electron transport chainGO:0022900140.023
intracellular protein transmembrane transportGO:006500240.023
larval developmentGO:00021641040.023
negative regulation of biosynthetic processGO:00098902770.023
organic hydroxy compound metabolic processGO:1901615830.022
myosin filament assemblyGO:003103450.022
substrate adhesion dependent cell spreadingGO:003444620.022
muscle contractionGO:0006936130.022
cellular response to organic substanceGO:00713101320.022
embryo development ending in birth or egg hatchingGO:00097921520.022
synaptic vesicle recyclingGO:0036465280.022
vesicle mediated transportGO:00161923810.022
response to heatGO:0009408630.022
organic substance transportGO:00717022570.021
response to decreased oxygen levelsGO:0036293580.021
monovalent inorganic cation transportGO:0015672400.021
regulation of molecular functionGO:00650092170.021
respiratory electron transport chainGO:0022904110.021
purine ribonucleoside triphosphate metabolic processGO:00092051190.021
protein modification processGO:00362114380.020
cellular response to oxygen containing compoundGO:1901701790.020
macromolecule catabolic processGO:00090571610.020
regulation of ion transmembrane transportGO:0034765270.020
appendage developmentGO:00487364010.020
glycogen biosynthetic processGO:000597820.020
cellular homeostasisGO:0019725800.020
cell motilityGO:00488702510.020
regionalizationGO:00030024160.020
negative regulation of cell cycleGO:00457861160.019
proteolysisGO:00065081920.019
rna localizationGO:00064031150.019
regulation of organelle organizationGO:00330431960.019
cellular carbohydrate biosynthetic processGO:003463770.019
cellular amine metabolic processGO:0044106120.019
cell type specific apoptotic processGO:0097285380.019
nucleoside monophosphate metabolic processGO:0009123520.019
spermatogenesisGO:00072832000.019
negative regulation of programmed cell deathGO:0043069720.018
neuromuscular junction developmentGO:00075281490.018
immune system processGO:00023763470.018
activation of mapk activityGO:000018790.018
negative regulation of cell deathGO:0060548810.018
axon developmentGO:00615642970.017
apoptotic processGO:00069151590.017
cellular response to endogenous stimulusGO:0071495800.017
positive regulation of developmental processGO:00510941430.017
regulation of cellular amino acid metabolic processGO:000652100.017
positive regulation of molecular functionGO:00440931360.017
positive regulation of cellular biosynthetic processGO:00313283160.017
divalent inorganic cation transportGO:0072511300.017
tube developmentGO:00352952440.017
carbohydrate derivative biosynthetic processGO:1901137850.016
pyridine nucleotide metabolic processGO:001936220.016
forebrain developmentGO:003090020.016
muscle system processGO:0003012210.016
cellular response to organonitrogen compoundGO:0071417360.016
nucleoside phosphate metabolic processGO:00067531620.016
regulation of cell substrate adhesionGO:001081020.016
imaginal disc derived wing morphogenesisGO:00074763370.016
nuclear divisionGO:00002803320.016
integrin mediated signaling pathwayGO:000722930.016
ribonucleoside metabolic processGO:00091191270.016
immune responseGO:00069552460.015
single organism cellular localizationGO:19025801800.015
endomembrane system organizationGO:00102561190.015
cell migrationGO:00164772380.015
developmental growthGO:00485892800.015
cellular catabolic processGO:00442483720.015
positive regulation of phosphorus metabolic processGO:00105621390.015
purine ribonucleotide metabolic processGO:00091501450.015
anion homeostasisGO:005508130.015
intracellular mrna localization involved in pattern specification processGO:0060810560.015
purine nucleoside triphosphate biosynthetic processGO:000914520.015
isoprenoid metabolic processGO:000672080.014
protein catabolic processGO:00301631010.014
multi organism reproductive behaviorGO:00447051210.014
morphogenesis of an epitheliumGO:00020092760.014
cellular protein localizationGO:00346131600.014
chemotaxisGO:00069352490.014
lateral inhibitionGO:00463312060.014
response to starvationGO:0042594970.014
positive regulation of macromolecule biosynthetic processGO:00105572830.014
regulation of multicellular organism growthGO:0040014400.014
ribose phosphate biosynthetic processGO:0046390280.014
pigment metabolic processGO:0042440840.013
positive regulation of peptidyl tyrosine phosphorylationGO:005073140.013
ribonucleotide metabolic processGO:00092591450.013
cellular response to peptide hormone stimulusGO:0071375280.013
positive regulation of phosphate metabolic processGO:00459371390.013
intracellular transportGO:00469072280.013
cellular carbohydrate catabolic processGO:004427520.013
positive regulation of nucleobase containing compound metabolic processGO:00459353320.013
regenerationGO:0031099160.013
purine nucleotide metabolic processGO:00061631460.013
regulation of phosphate metabolic processGO:00192202100.013
positive regulation of nucleotide metabolic processGO:0045981550.013
meiotic cell cycleGO:00513211710.013
nucleotide biosynthetic processGO:0009165340.013
spinal cord developmentGO:002151010.012
organic hydroxy compound catabolic processGO:190161640.012
negative regulation of cellular component organizationGO:00511291080.012
cellular response to nutrient levelsGO:0031669620.012
anatomical structure homeostasisGO:0060249970.012
cell adhesionGO:00071551360.012
skeletal muscle fiber developmentGO:004874130.012
regulation of hormone levelsGO:0010817400.012
cell agingGO:000756920.012
regulation of cellular ketone metabolic processGO:001056530.012
sperm mitochondrion organizationGO:003038270.012
negative regulation of cellular biosynthetic processGO:00313272770.012
negative regulation of developmental processGO:00510932010.012
eggshell formationGO:00307031050.012
regulation of purine nucleotide metabolic processGO:1900542620.012
regulation of cytoskeleton organizationGO:0051493890.012
endocytosisGO:00068973100.012
response to hypoxiaGO:0001666530.012
response to hexoseGO:000974630.012
oocyte differentiationGO:00099941450.012
nucleoside triphosphate metabolic processGO:00091411200.011
retina development in camera type eyeGO:006004140.011
regulation of nucleotide catabolic processGO:0030811480.011
sex differentiationGO:0007548810.011
regulation of cell cycle phase transitionGO:19019871300.011
positive regulation of synaptic transmissionGO:0050806150.011
epithelial cell differentiationGO:00308553220.011
myotube cell developmentGO:001490430.011
response to calcium ionGO:005159210.011
purine ribonucleoside triphosphate biosynthetic processGO:000920620.011
alcohol catabolic processGO:004616440.011
positive regulation of cellular amine metabolic processGO:003324000.011
neuron projection guidanceGO:00974852410.011
nitrogen compound transportGO:0071705850.011
regulation of intracellular signal transductionGO:19025312360.011
response to oxygen levelsGO:0070482590.011
peptidyl amino acid modificationGO:00181931050.011
intracellular signal transductionGO:00355563000.011
chromosome organizationGO:00512763600.011
taxisGO:00423303040.011
negative regulation of molecular functionGO:0044092510.011
cellular response to decreased oxygen levelsGO:0036294300.011
nucleoside catabolic processGO:00091641120.011
cellular response to oxidative stressGO:0034599280.011
negative regulation of neuron apoptotic processGO:0043524140.010
apoptotic signaling pathwayGO:0097190270.010
negative regulation of cell developmentGO:0010721620.010
mitochondrial transportGO:000683980.010
regulation of hemocyte proliferationGO:0035206370.010
positive regulation of response to stimulusGO:00485843230.010
epithelial tube morphogenesisGO:0060562880.010
ribose phosphate metabolic processGO:00196931450.010
imaginal disc derived appendage morphogenesisGO:00351143950.010
regulation of mitotic cell cycle phase transitionGO:19019901300.010
regulation of cell adhesionGO:0030155270.010

Pgk disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
glucose metabolism diseaseDOID:419400.843
carbohydrate metabolism diseaseDOID:005001300.843
acquired metabolic diseaseDOID:006015800.843
disease of metabolismDOID:001466700.843
disease of anatomical entityDOID:700.068
inherited metabolic disorderDOID:65500.051
kidney diseaseDOID:55700.035
urinary system diseaseDOID:1800.035
synucleinopathyDOID:005089000.010
nervous system diseaseDOID:86300.010
central nervous system diseaseDOID:33100.010
neurodegenerative diseaseDOID:128900.010