Drosophila melanogaster

257 known processes

spn-E (Dmel_CG3158)

spindle E

(Aliases: fs(3)hls,homeless,spn-E/hls,hls,CG3158,Dmel\CG3158,fs(1)hls,Spn-E,spn E,spnE)

spn-E biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
meiosis iGO:0007127590.996
meiotic cell cycle processGO:19030461320.991
intracellular mrna localizationGO:0008298660.990
oocyte differentiationGO:00099941450.985
regulation of pole plasm oskar mrna localizationGO:0007317270.982
transpositionGO:0032196130.982
negative regulation of transpositionGO:0010529120.982
pole plasm mrna localizationGO:0019094490.980
oocyte constructionGO:00073081120.980
oocyte developmentGO:00485991240.977
chromosome organizationGO:00512763600.966
oocyte anterior posterior axis specificationGO:0007314720.964
karyosome formationGO:0030717220.961
rna localizationGO:00064031150.957
germarium derived oocyte fate determinationGO:0007294260.950
germarium derived egg chamber formationGO:00072931010.948
oocyte axis specificationGO:00073091080.943
germarium derived oocyte differentiationGO:0030706290.940
intracellular mrna localization involved in anterior posterior axis specificationGO:0060811530.936
meiotic chromosome segregationGO:0045132590.925
meiotic nuclear divisionGO:00071261510.922
Mouse
regulation of gene expression epigeneticGO:00400291280.915
sister chromatid segregationGO:0000819920.894
anterior posterior pattern specificationGO:00099521360.883
dna recombinationGO:0006310320.880
cell maturationGO:00484691440.832
pole plasm assemblyGO:0007315610.825
posttranscriptional gene silencingGO:0016441460.819
axis specificationGO:00097981670.816
negative regulation of gene expressionGO:00106293870.809
segmentationGO:00352822070.803
meiotic cell cycleGO:00513211710.797
Mouse
dorsal appendage formationGO:0046843470.792
maternal determination of anterior posterior axis embryoGO:0008358740.787
regulation of transpositionGO:0010528130.773
pole plasm oskar mrna localizationGO:0045451460.764
pole plasm rna localizationGO:0007316520.754
dna metabolic processGO:00062592270.739
organelle fissionGO:00482853400.734
gene silencingGO:00164581380.691
anterior posterior axis specificationGO:00099481090.682
anterior posterior axis specification embryoGO:00085951030.680
cellular macromolecule localizationGO:00707272200.678
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.666
eggshell formationGO:00307031050.657
oocyte nucleus localization involved in oocyte dorsal ventral axis specificationGO:0051663120.656
negative regulation of biosynthetic processGO:00098902770.628
targeting of mrna for destruction involved in rna interferenceGO:003042340.627
chorion containing eggshell formationGO:00073041050.624
chromosome segregationGO:00070591570.621
cellular nitrogen compound catabolic processGO:00442701650.610
negative regulation of macromolecule biosynthetic processGO:00105582700.606
oocyte maturationGO:000155630.603
gene silencing by rnaGO:0031047570.598
embryonic axis specificationGO:00005781070.598
regulation of response to stressGO:00801342000.591
regulation of oocyte developmentGO:0060281270.573
negative regulation of cellular biosynthetic processGO:00313272770.561
cell divisionGO:00513012480.560
chromosome organization involved in meiosisGO:0070192100.545
oocyte dorsal ventral axis specificationGO:0007310340.535
developmental maturationGO:00217001720.512
positive regulation of nuclear transcribed mrna poly a tail shorteningGO:006021340.504
regulation of mitotic cell cycleGO:00073461900.503
blastoderm segmentationGO:00073501590.502
negative regulation of dna recombinationGO:004591020.489
nucleotide excision repairGO:000628980.486
eggshell chorion assemblyGO:0007306660.484
dna alkylationGO:000630540.473
Mouse
male gamete generationGO:00482322010.457
Mouse
spindle organizationGO:00070512530.455
female germ line stem cell asymmetric divisionGO:0048132140.455
regulation of nuclear transcribed mrna poly a tail shorteningGO:006021140.442
negative regulation of cellular metabolic processGO:00313243820.421
aromatic compound catabolic processGO:00194391660.419
pole plasm protein localizationGO:0007318100.416
nuclear divisionGO:00002803320.416
negative regulation of transcription dna templatedGO:00458922370.415
reciprocal dna recombinationGO:0035825190.412
tripartite regional subdivisionGO:00073511030.400
reciprocal meiotic recombinationGO:0007131190.386
nucleobase containing compound catabolic processGO:00346551650.384
regulation of cell divisionGO:0051302720.377
positive regulation of mrna catabolic processGO:006101450.373
mitotic spindle organizationGO:00070522200.350
regionalizationGO:00030024160.350
regulation of cell cycle processGO:00105641810.345
pirna metabolic processGO:0034587100.344
Mouse
regulation of meiosisGO:004002030.321
posttranscriptional regulation of gene expressionGO:00106081450.320
catabolic processGO:00090564090.316
cellular macromolecule catabolic processGO:00442651360.305
organelle assemblyGO:00709251980.302
dna repairGO:0006281540.291
dna methylation or demethylationGO:004472840.289
Mouse
pronuclear migrationGO:003504640.288
positive regulation of mrna processingGO:005068540.287
regulation of mrna 3 end processingGO:003144070.281
cellular catabolic processGO:00442483720.279
organic cyclic compound catabolic processGO:19013611680.273
intracellular mrna localization involved in pattern specification processGO:0060810560.272
male meiosisGO:0007140520.266
Mouse
mitotic cell cycle phase transitionGO:00447721380.262
female meiotic divisionGO:0007143700.262
cellular component assembly involved in morphogenesisGO:00109271510.259
regulation of cell cycleGO:00517262910.258
regulation of cell cycle phase transitionGO:19019871300.248
negative regulation of response to stimulusGO:00485852580.244
dna modificationGO:000630450.244
Mouse
mrna metabolic processGO:00160711240.237
negative regulation of mitotic cell cycle phase transitionGO:19019911030.230
negative regulation of nucleobase containing compound metabolic processGO:00459342610.229
negative regulation of mitotic cell cycleGO:00459301090.228
regulation of mitotic cell cycle phase transitionGO:19019901300.223
production of sirna involved in rna interferenceGO:0030422110.212
immune system processGO:00023763470.209
double strand break repairGO:0006302260.203
negative regulation of rna biosynthetic processGO:19026792400.202
meiotic sister chromatid segregationGO:004514460.197
microtubule organizing center organizationGO:00310231680.188
heterochromatin organization involved in chromatin silencingGO:007086890.186
regulation of embryonic pattern specificationGO:1902875270.184
cellular response to dna damage stimulusGO:00069742230.171
mrna catabolic processGO:0006402330.169
oocyte microtubule cytoskeleton organizationGO:0016325350.169
female germ line cyst formationGO:0048135420.158
germ line stem cell divisionGO:0042078250.156
posttranscriptional gene silencing by rnaGO:0035194450.153
regulation of mrna processingGO:0050684710.153
response to abiotic stimulusGO:00096283410.151
regulation of oskar mrna translationGO:004601180.151
regulation of multi organism processGO:00439001310.146
negative regulation of gene expression epigeneticGO:0045814770.145
negative regulation of cell cycle processGO:00109481090.144
chromatin silencingGO:0006342760.144
negative regulation of oskar mrna translationGO:000731950.141
regulation of cell proliferationGO:00421271630.138
embryonic pattern specificationGO:00098801740.136
meiotic chromosome separationGO:005130780.136
cell cycle phase transitionGO:00447701400.134
production of small rna involved in gene silencing by rnaGO:0070918150.134
single organism cellular localizationGO:19025801800.132
rna catabolic processGO:0006401370.132
negative regulation of nucleic acid templated transcriptionGO:19035072400.130
cytoplasm organizationGO:0007028640.128
regulation of nuclear divisionGO:0051783580.126
regulation of cell differentiationGO:00455953020.121
fertilizationGO:0009566260.117
Mouse
regulation of catabolic processGO:00098941700.116
meiotic spindle organizationGO:0000212360.112
positive regulation of response to stimulusGO:00485843230.108
negative regulation of nitrogen compound metabolic processGO:00511722650.104
spermatogenesisGO:00072832000.096
Mouse
dsrna fragmentationGO:0031050150.096
heterocycle catabolic processGO:00467001660.095
mrna processingGO:00063971040.090
rna processingGO:00063961470.089
regulation of transcription from rna polymerase ii promoterGO:00063573780.089
anatomical structure homeostasisGO:0060249970.089
positive regulation of nuclear transcribed mrna catabolic process deadenylation dependent decayGO:190015340.086
regulation of protein metabolic processGO:00512462560.084
transcription from rna polymerase ii promoterGO:00063663680.081
mitotic sister chromatid segregationGO:0000070870.081
germarium derived female germ line cyst formationGO:0030727420.081
germline stem cell asymmetric divisionGO:0098728150.080
ovarian follicle cell developmentGO:00307072480.078
programmed cell deathGO:00125012570.078
dna methylationGO:000630640.077
Mouse
dna biosynthetic processGO:0071897240.076
spindle assembly involved in female meiosisGO:0007056140.075
nuclear transcribed mrna catabolic processGO:0000956240.075
regulation of cellular catabolic processGO:00313291570.073
ribonucleoprotein complex subunit organizationGO:0071826280.072
mitotic dna integrity checkpointGO:0044774750.072
columnar cuboidal epithelial cell developmentGO:00020662490.072
mitotic chromosome condensationGO:0007076220.069
apoptotic processGO:00069151590.069
ncrna metabolic processGO:0034660430.069
Mouse
regulation of meiotic cell cycleGO:005144590.068
oocyte fate determinationGO:0030716270.068
negative regulation of rna metabolic processGO:00512532510.067
ovarian fusome organizationGO:0030723110.067
cellular response to dsrnaGO:0071359150.067
response to other organismGO:00517072930.063
organic substance catabolic processGO:19015753080.062
positive regulation of hydrolase activityGO:0051345780.060
negative regulation of cell differentiationGO:00455961430.059
positive regulation of cellular catabolic processGO:0031331950.059
response to dsrnaGO:0043331150.059
negative regulation of cell cycle phase transitionGO:19019881030.056
macromolecule catabolic processGO:00090571610.054
double strand break repair via nonhomologous end joiningGO:000630350.053
germ line cyst formationGO:0048134440.053
synaptonemal complex organizationGO:007019350.052
positive regulation of nitrogen compound metabolic processGO:00511733540.051
dorsal ventral pattern formationGO:00099531330.049
negative regulation of cellular component organizationGO:00511291080.048
regulation of nervous system developmentGO:00519602480.048
establishment or maintenance of cell polarityGO:00071631670.047
cell deathGO:00082192790.046
deathGO:00162652840.044
dna catabolic processGO:0006308160.044
positive regulation of defense responseGO:0031349590.044
regulation of cell developmentGO:00602842150.044
meiosis iiGO:0007135230.044
cell cycle checkpointGO:0000075950.044
positive regulation of mrna metabolic processGO:190331350.043
cellular protein complex assemblyGO:0043623710.043
rna 3 end processingGO:0031123450.043
regulation of hydrolase activityGO:0051336970.042
positive regulation of cellular biosynthetic processGO:00313283160.042
cell proliferationGO:00082832990.042
telomere organizationGO:0032200210.041
mitotic g2 dna damage checkpointGO:0007095690.040
g2 dna damage checkpointGO:0031572690.040
translationGO:0006412690.038
regulation of mrna metabolic processGO:1903311720.038
negative regulation of developmental processGO:00510932010.038
epithelial cell differentiationGO:00308553220.038
positive regulation of macromolecule metabolic processGO:00106044050.037
spermatid developmentGO:0007286980.036
protein complex assemblyGO:00064612000.036
immune responseGO:00069552460.036
regulation of anatomical structure morphogenesisGO:00226032420.035
positive regulation of protein metabolic processGO:00512471280.035
regulation of phosphorus metabolic processGO:00511742100.034
mitotic recombinationGO:000631220.034
regulation of multicellular organismal developmentGO:20000264140.034
positive regulation of macromolecule biosynthetic processGO:00105572830.034
chromosome condensationGO:0030261410.033
mrna polyadenylationGO:0006378110.033
regulation of cellular protein metabolic processGO:00322682430.032
chromatin organizationGO:00063252070.031
regulation of gene silencingGO:0060968630.031
negative regulation of cell cycleGO:00457861160.029
regulation of translationGO:0006417560.029
defense response to other organismGO:00985422250.029
nuclear transcribed mrna catabolic process deadenylation dependent decayGO:0000288140.029
protein localizationGO:00081042840.028
regulation of transcription by chromatin organizationGO:003440130.028
regulation of chromatin silencingGO:0031935360.028
regulation of defense responseGO:00313471020.027
regulation of hemocyte proliferationGO:0035206370.027
establishment of nucleus localizationGO:0040023260.026
mitotic g2 m transition checkpointGO:0044818700.026
positive regulation of immune system processGO:0002684680.025
regulation of organelle organizationGO:00330431960.025
positive regulation of cell cycle processGO:0090068280.025
striated muscle cell developmentGO:0055002500.025
spindle assemblyGO:0051225800.024
tube morphogenesisGO:00352391910.024
pole cell formationGO:0007279190.024
macromolecular complex assemblyGO:00650032560.024
cellular macromolecular complex assemblyGO:00346221530.024
stem cell developmentGO:0048864790.024
protein complex biogenesisGO:00702712010.023
oocyte localization involved in germarium derived egg chamber formationGO:0030720120.023
nuclear envelope organizationGO:000699870.023
negative regulation of cell divisionGO:0051782170.023
establishment of oocyte nucleus localization involved in oocyte dorsal ventral axis specificationGO:003072260.023
rna interferenceGO:0016246270.022
regulation of immune responseGO:00507761180.022
response to bacteriumGO:00096171980.022
response to temperature stimulusGO:00092661060.022
ribonucleoprotein complex assemblyGO:0022618230.021
positive regulation of atp catabolic processGO:190329130.021
intracellular signal transductionGO:00355563000.021
positive regulation of signalingGO:00230562430.020
ribonucleoside monophosphate metabolic processGO:0009161510.020
telomere maintenanceGO:0000723210.020
response to external biotic stimulusGO:00432072930.019
stem cell divisionGO:0017145690.019
regulation of developmental growthGO:00486381740.019
nucleus localizationGO:0051647340.019
negative regulation of protein metabolic processGO:0051248850.019
meiotic sister chromatid cohesionGO:005117760.019
defense response to bacteriumGO:00427421780.019
purine ribonucleoside monophosphate catabolic processGO:0009169380.019
phosphorylationGO:00163102940.019
regulation of cell deathGO:00109411730.019
mitotic nuclear divisionGO:00070672130.019
positive regulation of cell cycleGO:0045787430.018
sex differentiationGO:0007548810.018
regulation of cell maturationGO:1903429270.018
epithelial cell developmentGO:00020642740.018
positive regulation of translationGO:0045727120.018
positive regulation of rna metabolic processGO:00512542710.017
ribonucleoside monophosphate catabolic processGO:0009158390.017
polarity specification of dorsal ventral axisGO:000995160.017
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178650.017
positive regulation of catabolic processGO:00098961050.017
regulation of response to dna damage stimulusGO:2001020230.017
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630110.017
digestive tract morphogenesisGO:00485461270.017
small molecule metabolic processGO:00442813050.017
negative regulation of multicellular organismal processGO:00512411420.017
pole cell developmentGO:0007277260.017
purine ribonucleotide catabolic processGO:00091541090.017
regulation of apoptotic processGO:00429811300.017
spindle assembly involved in meiosisGO:0090306200.017
gland morphogenesisGO:00226121450.017
single fertilizationGO:0007338240.017
response to hypoxiaGO:0001666530.016
response to decreased oxygen levelsGO:0036293580.016
organophosphate catabolic processGO:00464341120.016
lateral inhibitionGO:00463312060.016
purine nucleoside monophosphate metabolic processGO:0009126500.016
centriole assemblyGO:0098534240.016
myofibril assemblyGO:0030239360.016
dna conformation changeGO:00711031050.015
regulation of catalytic activityGO:00507901850.015
digestive tract developmentGO:00485651490.015
membrane disassemblyGO:003039740.015
positive regulation of immune responseGO:0050778630.015
regulation of innate immune responseGO:0045088710.015
purine nucleoside monophosphate catabolic processGO:0009128380.015
purine ribonucleoside monophosphate metabolic processGO:0009167500.015
regulation of dna recombinationGO:000001840.015
regulation of dna metabolic processGO:0051052340.015
embryo development ending in birth or egg hatchingGO:00097921520.014
germ line stem cell maintenanceGO:0030718500.014
nucleoside monophosphate catabolic processGO:0009125390.014
positive regulation of phosphate metabolic processGO:00459371390.014
mitotic cell cycle checkpointGO:0007093880.014
response to biotic stimulusGO:00096072940.014
developmental programmed cell deathGO:00106231380.014
regulation of double strand break repairGO:200077930.014
regulation of molecular functionGO:00650092170.014
oxoacid metabolic processGO:00434361030.014
humoral immune responseGO:00069591170.014
response to oxygen containing compoundGO:19017002000.013
positive regulation of catalytic activityGO:00430851180.013
positive regulation of intracellular signal transductionGO:19025331160.013
regulation of phosphate metabolic processGO:00192202100.013
heterochromatin organizationGO:0070828250.013
purine nucleoside triphosphate metabolic processGO:00091441190.013
development of primary sexual characteristicsGO:0045137500.013
endocytosisGO:00068973100.012
negative regulation of cell communicationGO:00106482230.012
establishment of localization in cellGO:00516494020.012
establishment or maintenance of microtubule cytoskeleton polarityGO:0030951410.012
positive regulation of cellular protein metabolic processGO:00322701180.012
regulation of nucleocytoplasmic transportGO:0046822350.012
regulation of reproductive processGO:2000241540.012
regulation of signal transduction by p53 class mediatorGO:190179610.012
cellular response to organic cyclic compoundGO:0071407320.012
non recombinational repairGO:000072670.012
establishment of spindle orientationGO:0051294180.012
polarity specification of anterior posterior axisGO:000994950.012
meiotic chromosome condensationGO:001003230.012
nuclear migrationGO:0007097200.012
cystoblast divisionGO:0007282100.012
positive regulation of dna endoreduplicationGO:003287740.011
mitotic dna damage checkpointGO:0044773740.011
regulation of transposition rna mediatedGO:001052530.011
spermatid differentiationGO:00485151140.011
ribonucleoside catabolic processGO:00424541120.011
gliogenesisGO:0042063800.011
regulation of cellular response to stressGO:0080135890.011
negative regulation of cellular protein metabolic processGO:0032269850.011
maintenance of location in cellGO:0051651280.011
nuclear transcribed mrna poly a tail shorteningGO:0000289120.011
organophosphate metabolic processGO:00196371950.011
chromosome separationGO:0051304420.011
positive regulation of nucleobase containing compound metabolic processGO:00459353320.011
negative regulation of transcription factor import into nucleusGO:004299240.011
cytoskeleton dependent cytokinesisGO:0061640810.011
response to heatGO:0009408630.011
nucleoside triphosphate catabolic processGO:00091431080.011
photoreceptor cell differentiationGO:00465301700.011
cell fate determinationGO:0001709910.010
cellular protein modification processGO:00064644380.010
atp catabolic processGO:0006200380.010
positive regulation of innate immune responseGO:0045089380.010
stem cell differentiationGO:00488631170.010
oocyte microtubule cytoskeleton polarizationGO:0008103220.010
nucleoside metabolic processGO:00091161270.010
lipid localizationGO:0010876540.010
response to nitrogen compoundGO:1901698900.010
microtubule anchoringGO:0034453110.010

spn-E disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.050
cancerDOID:16200.036
disease of cellular proliferationDOID:1456600.036
organ system cancerDOID:005068600.011
thoracic cancerDOID:509300.011