Drosophila melanogaster

93 known processes

Zyx102EF (Dmel_CG32018)

CG32018 gene product from transcript CG32018-RA

(Aliases: zyx102,zyxin,BcDNA:LD06023,lim,Zyx102,Lim102EF,Zyxin,ZYX102,Dmel\CG32018,DLim-1,DmLIM-1,CG32018)

Zyx102EF biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
intracellular signal transductionGO:00355563000.678
negative regulation of signalingGO:00230572190.595
negative regulation of macromolecule biosynthetic processGO:00105582700.450
negative regulation of response to stimulusGO:00485852580.433
cellular response to dna damage stimulusGO:00069742230.361
cellular response to external stimulusGO:0071496660.321
regulation of catabolic processGO:00098941700.317
neuromuscular junction developmentGO:00075281490.313
transcription from rna polymerase ii promoterGO:00063663680.306
wnt signaling pathwayGO:0016055980.276
positive regulation of cellular biosynthetic processGO:00313283160.272
sensory organ morphogenesisGO:00905962600.265
regulation of proteolysisGO:0030162870.262
regulation of growthGO:00400082330.260
positive regulation of nucleic acid templated transcriptionGO:19035082660.258
nucleocytoplasmic transportGO:0006913720.250
regulation of cellular protein metabolic processGO:00322682430.238
negative regulation of signal transductionGO:00099682060.238
regulation of transcription from rna polymerase ii promoterGO:00063573780.236
negative regulation of cellular metabolic processGO:00313243820.229
positive regulation of signal transductionGO:00099672230.217
negative regulation of cell communicationGO:00106482230.215
negative regulation of wnt signaling pathwayGO:0030178280.212
regulation of phosphate metabolic processGO:00192202100.211
negative regulation of gene expressionGO:00106293870.210
regulation of wnt signaling pathwayGO:0030111680.208
regulation of intracellular signal transductionGO:19025312360.203
spermatid developmentGO:0007286980.199
regulation of protein metabolic processGO:00512462560.190
regulation of intracellular protein transportGO:0033157460.190
establishment of localization in cellGO:00516494020.183
aromatic compound catabolic processGO:00194391660.177
protein modification processGO:00362114380.174
negative regulation of developmental growthGO:0048640640.171
regulation of phosphorus metabolic processGO:00511742100.171
embryonic morphogenesisGO:00485982060.170
regulation of multicellular organismal developmentGO:20000264140.161
positive regulation of transcription dna templatedGO:00458932660.157
protein modification by small protein conjugation or removalGO:00706471060.152
gastrulationGO:0007369700.148
regulation of cellular catabolic processGO:00313291570.145
positive regulation of gtpase activityGO:0043547430.143
regulation of cytoplasmic transportGO:1903649470.141
compound eye developmentGO:00487493070.138
regulation of anatomical structure morphogenesisGO:00226032420.137
tube developmentGO:00352952440.130
molting cycle chitin based cuticleGO:0007591560.129
wing disc morphogenesisGO:00074723440.129
cell proliferationGO:00082832990.127
positive regulation of wnt signaling pathwayGO:0030177250.127
photoreceptor cell differentiationGO:00465301700.124
intracellular transportGO:00469072280.123
positive regulation of response to stimulusGO:00485843230.123
cellular catabolic processGO:00442483720.121
regulation of endopeptidase activityGO:0052548360.120
cuticle pigmentationGO:0048067220.119
catabolic processGO:00090564090.118
regulation of cell differentiationGO:00455953020.115
positive regulation of phosphate metabolic processGO:00459371390.112
protein processingGO:0016485680.111
cell divisionGO:00513012480.110
cellular protein modification processGO:00064644380.107
regulation of macroautophagyGO:0016241150.104
positive regulation of biosynthetic processGO:00098913160.103
single organism behaviorGO:00447083910.102
regulation of establishment of protein localizationGO:0070201610.102
cellular macromolecule localizationGO:00707272200.101
regulation of nervous system developmentGO:00519602480.101
regulation of phosphorylationGO:00423251470.101
protein maturationGO:0051604710.098
negative regulation of nucleic acid templated transcriptionGO:19035072400.097
protein localizationGO:00081042840.097
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.096
nucleoside catabolic processGO:00091641120.093
positive regulation of nitrogen compound metabolic processGO:00511733540.091
gene silencingGO:00164581380.090
positive regulation of cell communicationGO:00106472500.090
response to organic substanceGO:00100332840.090
positive regulation of rna biosynthetic processGO:19026802660.089
regulation of synapse structure and activityGO:00508031280.088
digestive tract developmentGO:00485651490.088
cytokinesisGO:0000910900.087
tube morphogenesisGO:00352391910.086
negative regulation of protein processingGO:0010955310.085
negative regulation of synaptic growth at neuromuscular junctionGO:0045886390.085
compound eye morphogenesisGO:00017452490.084
imaginal disc derived appendage developmentGO:00487373990.083
negative regulation of rna metabolic processGO:00512532510.082
locomotory behaviorGO:00076261760.081
negative regulation of nucleobase containing compound metabolic processGO:00459342610.081
response to radiationGO:00093141550.080
response to extracellular stimulusGO:00099911160.079
posttranscriptional regulation of gene expressionGO:00106081450.078
negative regulation of growthGO:0045926840.077
regulation of autophagyGO:0010506620.077
spermatogenesisGO:00072832000.077
carbohydrate derivative metabolic processGO:19011352170.077
organonitrogen compound metabolic processGO:19015643180.075
synapse organizationGO:00508081960.075
positive regulation of macromolecule metabolic processGO:00106044050.074
growthGO:00400073590.073
proteolysisGO:00065081920.073
positive regulation of nucleobase containing compound metabolic processGO:00459353320.073
positive regulation of rna metabolic processGO:00512542710.070
cellular response to oxidative stressGO:0034599280.070
single organism intracellular transportGO:19025822070.068
positive regulation of gene expressionGO:00106282900.068
positive regulation of protein metabolic processGO:00512471280.067
negative regulation of cell differentiationGO:00455961430.066
positive regulation of catalytic activityGO:00430851180.066
positive regulation of signalingGO:00230562430.065
cytoplasmic transportGO:00164821300.064
negative regulation of cellular protein metabolic processGO:0032269850.064
salivary gland cell autophagic cell deathGO:0035071830.063
regulation of intracellular transportGO:0032386640.063
positive regulation of catabolic processGO:00098961050.062
positive regulation of developmental processGO:00510941430.062
negative regulation of programmed cell deathGO:0043069720.062
positive regulation of organelle organizationGO:0010638650.061
regulation of translationGO:0006417560.061
purine nucleotide metabolic processGO:00061631460.059
organonitrogen compound biosynthetic processGO:19015661170.058
central nervous system developmentGO:00074172010.058
carbohydrate derivative catabolic processGO:19011361180.057
small molecule metabolic processGO:00442813050.056
adult chitin containing cuticle pigmentationGO:0048085160.056
negative regulation of biosynthetic processGO:00098902770.056
imaginal disc derived wing vein specificationGO:0007474480.054
regulation of hydrolase activityGO:0051336970.053
nuclear transportGO:0051169720.052
negative regulation of peptidyl tyrosine phosphorylationGO:005073260.051
tissue morphogenesisGO:00487292970.051
sister chromatid segregationGO:0000819920.051
neuron maturationGO:0042551310.050
regulation of molecular functionGO:00650092170.050
establishment of protein localizationGO:00451841630.050
developmental maturationGO:00217001720.049
chromosome segregationGO:00070591570.049
sperm individualizationGO:0007291480.049
purine ribonucleoside triphosphate catabolic processGO:00092071080.048
organic substance catabolic processGO:19015753080.048
regulation of cellular component biogenesisGO:00440872010.048
purine ribonucleoside catabolic processGO:00461301120.048
organelle assemblyGO:00709251980.048
negative regulation of protein metabolic processGO:0051248850.047
macromolecule catabolic processGO:00090571610.047
single organism carbohydrate metabolic processGO:0044723720.046
cuticle developmentGO:0042335860.045
protein localization to nucleusGO:0034504550.044
rhythmic behaviorGO:0007622760.044
neurological system processGO:00508773580.043
regulation of mitotic cell cycleGO:00073461900.043
positive regulation of cellular component organizationGO:00511301560.043
regulation of catalytic activityGO:00507901850.042
vesicle mediated transportGO:00161923810.042
regulation of gtp catabolic processGO:0033124440.042
regulation of ras protein signal transductionGO:0046578930.042
protein catabolic processGO:00301631010.042
establishment of organelle localizationGO:00516561220.041
response to organic cyclic compoundGO:0014070890.041
positive regulation of macromolecule biosynthetic processGO:00105572830.040
cellular response to nutrient levelsGO:0031669620.040
synapse assemblyGO:00074161430.040
regulation of cell developmentGO:00602842150.040
ribonucleoside triphosphate catabolic processGO:00092031080.040
regulation of peptidase activityGO:0052547390.040
chitin based cuticle sclerotizationGO:0007593190.039
positive regulation of phosphorus metabolic processGO:00105621390.039
nucleobase containing compound catabolic processGO:00346551650.039
positive regulation of mapk cascadeGO:0043410630.039
positive regulation of intracellular signal transductionGO:19025331160.038
response to nutrient levelsGO:00316671140.038
eye morphogenesisGO:00485922600.038
post embryonic appendage morphogenesisGO:00351203850.038
carbohydrate derivative biosynthetic processGO:1901137850.037
cellular nitrogen compound catabolic processGO:00442701650.037
regulation of protein import into nucleusGO:0042306280.037
negative regulation of cellular biosynthetic processGO:00313272770.037
cytoskeleton dependent cytokinesisGO:0061640810.036
regulation of cellular localizationGO:00603411360.036
muscle structure developmentGO:00610612240.035
glycoprotein metabolic processGO:0009100410.035
digestive system developmentGO:00551231490.035
cell fate determinationGO:0001709910.035
purine containing compound metabolic processGO:00725211550.034
synaptic growth at neuromuscular junctionGO:00511241190.034
cell deathGO:00082192790.034
cellular response to extracellular stimulusGO:0031668640.034
regulation of developmental growthGO:00486381740.034
protein complex assemblyGO:00064612000.034
protein ubiquitinationGO:0016567700.033
cellular response to starvationGO:0009267610.033
cellular protein localizationGO:00346131600.033
female meiotic divisionGO:0007143700.033
regulation of synapse assemblyGO:0051963940.033
amine metabolic processGO:0009308120.033
chromosome organizationGO:00512763600.033
salivary gland histolysisGO:0035070880.033
regulation of mapk cascadeGO:0043408920.033
rhythmic processGO:00485111060.032
phosphorylationGO:00163102940.032
gland developmentGO:00487321910.031
response to external biotic stimulusGO:00432072930.031
purine nucleoside triphosphate catabolic processGO:00091461080.031
negative regulation of developmental processGO:00510932010.031
regulation of nucleocytoplasmic transportGO:0046822350.030
negative regulation of transcription dna templatedGO:00458922370.030
regulation of cellular response to stressGO:0080135890.030
ras protein signal transductionGO:0007265880.030
response to abiotic stimulusGO:00096283410.030
nuclear importGO:0051170510.030
protein import into nucleusGO:0006606510.030
gland morphogenesisGO:00226121450.029
positive regulation of molecular functionGO:00440931360.029
nucleobase containing small molecule metabolic processGO:00550861740.029
nucleoside triphosphate metabolic processGO:00091411200.029
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.029
positive regulation of cellular catabolic processGO:0031331950.029
skeletal muscle organ developmentGO:0060538480.028
male gamete generationGO:00482322010.028
positive regulation of cellular protein metabolic processGO:00322701180.028
carbohydrate metabolic processGO:0005975820.028
eye developmentGO:00016543230.028
signal transduction by phosphorylationGO:00230141070.028
nucleus localizationGO:0051647340.028
stem cell differentiationGO:00488631170.027
mitotic cytokinesisGO:0000281500.027
lipid metabolic processGO:00066291210.027
carbohydrate biosynthetic processGO:0016051170.027
positive regulation of lipid biosynthetic processGO:004688930.027
ribonucleoside triphosphate metabolic processGO:00091991190.027
regulation of transportGO:00510491810.027
activation of cysteine type endopeptidase activityGO:0097202170.027
imaginal disc derived appendage morphogenesisGO:00351143950.026
mapk cascadeGO:00001651070.026
nucleoside phosphate metabolic processGO:00067531620.026
segment specificationGO:0007379330.026
regulation of small gtpase mediated signal transductionGO:0051056930.026
negative regulation of erk1 and erk2 cascadeGO:007037330.026
mitotic sister chromatid segregationGO:0000070870.026
purine nucleoside catabolic processGO:00061521120.026
heterocycle catabolic processGO:00467001660.025
positive regulation of immune responseGO:0050778630.025
regulation of cell proliferationGO:00421271630.025
positive regulation of cysteine type endopeptidase activityGO:2001056240.025
erk1 and erk2 cascadeGO:0070371390.025
proteolysis involved in cellular protein catabolic processGO:0051603830.025
positive regulation of endopeptidase activityGO:0010950260.025
negative regulation of endopeptidase activityGO:0010951110.025
cellular macromolecule catabolic processGO:00442651360.025
negative regulation of cell cycleGO:00457861160.025
organonitrogen compound catabolic processGO:19015651280.024
negative regulation of mitotic cell cycle phase transitionGO:19019911030.024
exocrine system developmentGO:00352721620.024
regulation of immune system processGO:00026821760.024
regulation of cellular amino acid metabolic processGO:000652100.024
regulation of carbohydrate metabolic processGO:0006109100.024
regulation of gene expression epigeneticGO:00400291280.024
regulation of localizationGO:00328792750.024
endocytosisGO:00068973100.024
cellularizationGO:0007349900.023
regulation of cell deathGO:00109411730.023
gtp metabolic processGO:0046039720.023
olfactory behaviorGO:0042048970.023
negative regulation of proteolysisGO:0045861310.023
single organism catabolic processGO:00447122280.023
protein importGO:0017038550.023
regulation of protein processingGO:0070613320.023
regulation of protein localization to nucleusGO:1900180290.023
negative regulation of phosphorus metabolic processGO:0010563450.022
response to starvationGO:0042594970.022
positive regulation of hydrolase activityGO:0051345780.022
ribose phosphate metabolic processGO:00196931450.022
translationGO:0006412690.022
digestive tract morphogenesisGO:00485461270.022
cellular response to chemical stimulusGO:00708871990.022
regulation of microtubule based processGO:0032886490.022
negative regulation of nitrogen compound metabolic processGO:00511722650.022
photoreceptor cell developmentGO:0042461960.022
dendrite developmentGO:00163582040.022
histolysisGO:00075591020.022
adult locomotory behaviorGO:0008344760.022
organelle localizationGO:00516401480.021
learning or memoryGO:00076111410.021
regulation of multi organism processGO:00439001310.021
circadian rhythmGO:00076231050.021
muscle organ developmentGO:00075171270.021
positive regulation of proteolysisGO:0045862520.021
organophosphate biosynthetic processGO:0090407460.021
cellular carbohydrate metabolic processGO:0044262220.021
purine nucleoside metabolic processGO:00422781270.021
purine ribonucleoside triphosphate metabolic processGO:00092051190.021
intracellular protein transportGO:00068861040.021
negative regulation of apoptotic processGO:0043066630.021
response to bacteriumGO:00096171980.021
regulation of nucleotide metabolic processGO:0006140620.021
single organism cellular localizationGO:19025801800.021
response to nitrogen compoundGO:1901698900.021
regulation of ras gtpase activityGO:0032318380.020
nephron morphogenesisGO:007202830.020
regulation of gtpase activityGO:0043087440.020
nucleoside triphosphate catabolic processGO:00091431080.020
morphogenesis of an epitheliumGO:00020092760.020
regulation of purine nucleotide metabolic processGO:1900542620.020
sensory perception of chemical stimulusGO:00076061160.020
camera type eye morphogenesisGO:004859320.020
meiotic cell cycleGO:00513211710.020
asymmetric protein localizationGO:0008105330.020
cellular amine metabolic processGO:0044106120.020
somatic muscle developmentGO:0007525660.020
cell growthGO:00160491080.019
negative regulation of protein maturationGO:1903318310.019
negative regulation of cell cycle processGO:00109481090.019
gene silencing by rnaGO:0031047570.019
cellular protein catabolic processGO:0044257830.019
cell type specific apoptotic processGO:0097285380.019
polysaccharide biosynthetic processGO:000027170.019
organic cyclic compound catabolic processGO:19013611680.019
protein modification by small protein conjugationGO:0032446790.018
oxoacid metabolic processGO:00434361030.018
morphogenesis of a branching structureGO:0001763450.018
regulation of protein modification processGO:00313991120.018
developmental growthGO:00485892800.018
regulation of cell divisionGO:0051302720.018
neural precursor cell proliferationGO:0061351750.018
dendrite morphogenesisGO:00488131990.018
enzyme linked receptor protein signaling pathwayGO:00071671790.018
single organism nuclear importGO:1902593510.018
nucleoside metabolic processGO:00091161270.018
positive regulation of purine nucleotide catabolic processGO:0033123460.018
positive regulation of ras gtpase activityGO:0032320360.018
regulation of microtubule cytoskeleton organizationGO:0070507410.018
regulation of protein localizationGO:0032880760.018
instar larval developmentGO:0002168550.018
appendage morphogenesisGO:00351073970.018
localization of cellGO:00516742570.018
spermatid differentiationGO:00485151140.018
regulation of stress activated mapk cascadeGO:0032872410.017
protein phosphorylationGO:00064681690.017
positive regulation of gtp catabolic processGO:0033126430.017
synaptic transmissionGO:00072682880.017
lipid biosynthetic processGO:0008610460.017
learningGO:0007612750.017
macroautophagyGO:0016236420.017
positive regulation of growthGO:0045927750.017
nucleotide metabolic processGO:00091171610.017
organelle fissionGO:00482853400.017
regulation of synaptic transmissionGO:0050804690.017
protein modification by small protein removalGO:0070646280.017
negative regulation of cell deathGO:0060548810.017
meiosis iGO:0007127590.017
forebrain developmentGO:003090020.017
regulation of cellular protein catabolic processGO:1903362440.017
organic substance transportGO:00717022570.017
small gtpase mediated signal transductionGO:0007264880.016
negative regulation of catabolic processGO:0009895360.016
regulation of cellular ketone metabolic processGO:001056530.016
eye photoreceptor cell developmentGO:0042462810.016
regulation of i kappab kinase nf kappab signalingGO:004312220.016
regulation of cellular amine metabolic processGO:003323830.016
dopamine metabolic processGO:004241770.016
organophosphate metabolic processGO:00196371950.016
neuroblast divisionGO:0055057350.016
purine containing compound biosynthetic processGO:0072522300.015
regulation of response to nutrient levelsGO:0032107180.015
tissue deathGO:00162711020.015
negative regulation of erbb signaling pathwayGO:1901185290.015
stress activated protein kinase signaling cascadeGO:0031098550.015
salivary gland morphogenesisGO:00074351450.015
olfactory learningGO:0008355560.015
triglyceride biosynthetic processGO:001943220.015
regulation of cell cycle processGO:00105641810.015
establishment of protein localization to organelleGO:0072594620.015
carboxylic acid metabolic processGO:0019752920.015
eye photoreceptor cell differentiationGO:00017541450.015
regulation of synaptic growth at neuromuscular junctionGO:0008582890.015
inter male aggressive behaviorGO:0002121600.015
cellular macromolecular complex assemblyGO:00346221530.015
autophagic cell deathGO:0048102830.015
positive regulation of purine nucleotide metabolic processGO:1900544550.015
regulation of erk1 and erk2 cascadeGO:0070372390.015
protein transportGO:00150311550.015
larval developmentGO:00021641040.015
regulation of organelle organizationGO:00330431960.014
regulation of nucleotide catabolic processGO:0030811480.014
negative regulation of intracellular signal transductionGO:1902532570.014
protein complex biogenesisGO:00702712010.014
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.014
purine nucleotide catabolic processGO:00061951090.014
negative regulation of cytoplasmic transportGO:190365080.014
glycosyl compound metabolic processGO:19016571270.014
regulation of transcription factor import into nucleusGO:0042990220.014
regulation of apoptotic processGO:00429811300.014
endosomal transportGO:0016197440.014
regulation of immune responseGO:00507761180.014
positive regulation of ras protein signal transductionGO:0046579430.014
chromatin remodelingGO:0006338720.013
immune system processGO:00023763470.013
posttranscriptional gene silencingGO:0016441460.013
protein targeting to nucleusGO:0044744510.013
peptidyl tyrosine phosphorylationGO:0018108240.013
nucleoside phosphate catabolic processGO:19012921100.013
regulation of epithelial cell proliferationGO:005067840.013
phagocytosisGO:00069092150.013
sensory perceptionGO:00076001960.013
protein heterooligomerizationGO:005129140.013
apoptotic processGO:00069151590.013
cellular response to endogenous stimulusGO:0071495800.013
developmental programmed cell deathGO:00106231380.013
meiotic cell cycle processGO:19030461320.013
immune response activating signal transductionGO:000275720.012
regulation of developmental pigmentationGO:0048070240.012
spindle organizationGO:00070512530.012
imaginal disc growthGO:0007446370.012
cytoplasmic microtubule organizationGO:0031122220.012
response to biotic stimulusGO:00096072940.012
segmentationGO:00352822070.012
positive regulation of cellular component biogenesisGO:0044089800.012
negative regulation of nervous system developmentGO:0051961920.012
embryonic pattern specificationGO:00098801740.012
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052240.012
stem cell proliferationGO:0072089880.012
rho protein signal transductionGO:0007266140.012
protein targetingGO:0006605640.012
compound eye photoreceptor cell differentiationGO:00017511400.012
establishment of spindle localizationGO:0051293220.012
immune effector processGO:0002252980.012
cell migrationGO:00164772380.012
glycoprotein biosynthetic processGO:0009101410.012
microtubule cytoskeleton organization involved in mitosisGO:1902850520.011
guanosine containing compound catabolic processGO:1901069740.011
organic acid metabolic processGO:00060821030.011
wound healingGO:0042060750.011
adult behaviorGO:00305341370.011
purine ribonucleotide catabolic processGO:00091541090.011
stem cell maintenanceGO:0019827670.011
positive regulation of i kappab kinase nf kappab signalingGO:004312310.011
activation of jun kinase activityGO:000725730.011
cognitionGO:00508901410.011
imaginal disc derived wing margin morphogenesisGO:0008587410.011
response to endogenous stimulusGO:00097191190.011
regulation of programmed cell deathGO:00430671520.011
nf kappab import into nucleusGO:004234810.011
gtp catabolic processGO:0006184720.011
posttranscriptional gene silencing by rnaGO:0035194450.011
positive regulation of cell developmentGO:0010720610.010
programmed cell deathGO:00125012570.010
negative regulation of mapk cascadeGO:0043409230.010
negative regulation of mitotic cell cycleGO:00459301090.010
regulation of protein modification by small protein conjugation or removalGO:1903320250.010
imaginal disc derived wing morphogenesisGO:00074763370.010
synaptic vesicle localizationGO:0097479530.010
positive regulation of developmental growthGO:0048639620.010
cellular amino acid metabolic processGO:0006520610.010
purine nucleoside triphosphate metabolic processGO:00091441190.010
positive regulation of jun kinase activityGO:004350740.010
leg disc developmentGO:0035218920.010
golgi organizationGO:0007030660.010
negative regulation of cellular catabolic processGO:0031330340.010
meiotic nuclear divisionGO:00071261510.010
circulatory system developmentGO:0072359820.010
regulation of transferase activityGO:0051338580.010
nephron tubule morphogenesisGO:007207830.010
mitotic dna integrity checkpointGO:0044774750.010

Zyx102EF disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
organ system cancerDOID:005068600.018
cancerDOID:16200.018
disease of cellular proliferationDOID:1456600.018
nervous system diseaseDOID:86300.012
disease of anatomical entityDOID:700.012