Drosophila melanogaster

58 known processes

spn-B (Dmel_CG3325)

spindle B

(Aliases: Dmel\CG3325,rad51-like,Rad51,spnB,SpnB,XRCC3,CG3325)

spn-B biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
reciprocal meiotic recombinationGO:0007131191.000
germarium derived oocyte differentiationGO:0030706290.999
germarium derived egg chamber formationGO:00072931010.999
chorion containing eggshell formationGO:00073041050.998
karyosome formationGO:0030717220.993
polarity specification of dorsal ventral axisGO:000995160.991
germarium derived oocyte fate determinationGO:0007294260.991
reciprocal dna recombinationGO:0035825190.990
dna recombinationGO:0006310320.990
Human
recombinational repairGO:0000725130.985
Human
eggshell chorion assemblyGO:0007306660.979
meiosis iGO:0007127590.974
dorsal appendage formationGO:0046843470.965
columnar cuboidal epithelial cell differentiationGO:00020652560.960
eggshell formationGO:00307031050.957
polarity specification of anterior posterior axisGO:000994950.955
meiotic chromosome segregationGO:0045132590.955
organelle fissionGO:00482853400.955
ovarian follicle cell developmentGO:00307072480.950
meiotic cell cycleGO:00513211710.944
meiotic cell cycle processGO:19030461320.939
meiotic nuclear divisionGO:00071261510.935
double strand break repair via homologous recombinationGO:0000724130.919
Human
oocyte differentiationGO:00099941450.901
dna metabolic processGO:00062592270.890
Human
chromosome organizationGO:00512763600.889
dna damage checkpointGO:0000077780.877
columnar cuboidal epithelial cell developmentGO:00020662490.876
cellular response to dna damage stimulusGO:00069742230.818
Human
dorsal ventral axis specificationGO:0009950660.816
cell cycle checkpointGO:0000075950.809
Human
chromosome segregationGO:00070591570.808
dorsal ventral pattern formationGO:00099531330.765
specification of axis polarityGO:006500160.728
regulation of mitotic cell cycle phase transitionGO:19019901300.728
Human
dna geometric changeGO:0032392160.722
dna integrity checkpointGO:0031570810.718
double strand break repair via synthesis dependent strand annealingGO:004500360.710
g2 dna damage checkpointGO:0031572690.709
resolution of meiotic recombination intermediatesGO:000071260.691
axis specificationGO:00097981670.678
nuclear divisionGO:00002803320.674
mitotic cell cycle phase transitionGO:00447721380.665
epithelial cell developmentGO:00020642740.657
oocyte fate determinationGO:0030716270.649
double strand break repairGO:0006302260.635
Human
regulation of cell cycle processGO:00105641810.620
Human
regulation of cell cycle phase transitionGO:19019871300.619
Human
regulation of mitotic cell cycleGO:00073461900.604
Human
nucleotide excision repairGO:000628980.582
oocyte localization involved in germarium derived egg chamber formationGO:0030720120.525
mitotic dna damage checkpointGO:0044773740.505
oocyte nucleus localization involved in oocyte dorsal ventral axis specificationGO:0051663120.502
dna repairGO:0006281540.493
Human
cellular component assembly involved in morphogenesisGO:00109271510.475
oocyte dorsal ventral axis specificationGO:0007310340.466
aromatic compound catabolic processGO:00194391660.462
Human
positive regulation of mitotic cell cycle phase transitionGO:1901992200.455
female meiosis chromosome segregationGO:0016321330.452
microtubule organizing center organizationGO:00310231680.426
Human
negative regulation of cell cycle phase transitionGO:19019881030.390
Human
cell cycle phase transitionGO:00447701400.386
double strand break repair via nonhomologous end joiningGO:000630350.380
female meiotic divisionGO:0007143700.374
regionalizationGO:00030024160.358
heterocycle catabolic processGO:00467001660.357
Human
oocyte developmentGO:00485991240.330
dna duplex unwindingGO:0032508160.328
oocyte axis specificationGO:00073091080.328
anterior posterior pattern specificationGO:00099521360.326
organic cyclic compound catabolic processGO:19013611680.315
Human
regulation of cell cycleGO:00517262910.315
Human
dna synthesis involved in dna repairGO:000073150.308
nucleobase containing compound catabolic processGO:00346551650.303
Human
male gamete generationGO:00482322010.302
anterior posterior axis specificationGO:00099481090.287
spermatogenesisGO:00072832000.285
oocyte anterior posterior axis specificationGO:0007314720.283
cell fate determinationGO:0001709910.282
sister chromatid segregationGO:0000819920.273
non recombinational repairGO:000072670.273
organic substance catabolic processGO:19015753080.262
Human
mitotic dna integrity checkpointGO:0044774750.260
cellular catabolic processGO:00442483720.253
Human
cellular nitrogen compound catabolic processGO:00442701650.243
Human
response to abiotic stimulusGO:00096283410.241
actin cytoskeleton organizationGO:00300362060.221
male meiosisGO:0007140520.219
chromosome separationGO:0051304420.218
negative regulation of cell cycleGO:00457861160.207
Human
cellular macromolecule catabolic processGO:00442651360.201
Human
gene silencingGO:00164581380.197
telomere maintenance via recombinationGO:000072210.191
positive regulation of macromolecule biosynthetic processGO:00105572830.187
macromolecule catabolic processGO:00090571610.182
Human
mitotic g2 m transition checkpointGO:0044818700.177
epithelial cell differentiationGO:00308553220.169
positive regulation of mitotic cell cycleGO:0045931340.169
Human
oocyte constructionGO:00073081120.165
cellular macromolecule localizationGO:00707272200.154
purine ribonucleoside monophosphate metabolic processGO:0009167500.151
mitotic g2 dna damage checkpointGO:0007095690.150
cell divisionGO:00513012480.149
maternal determination of anterior posterior axis embryoGO:0008358740.142
g2 m transition of mitotic cell cycleGO:0000086190.132
dna catabolic processGO:0006308160.132
Human
small molecule metabolic processGO:00442813050.128
rna localizationGO:00064031150.127
transcription from rna polymerase ii promoterGO:00063663680.127
negative regulation of mitotic cell cycle phase transitionGO:19019911030.124
Human
response to organic substanceGO:00100332840.112
response to organonitrogen compoundGO:0010243750.109
intracellular mrna localizationGO:0008298660.105
dorsal ventral axis specification ovarian follicular epitheliumGO:0008069130.100
regulation of gene expression epigeneticGO:00400291280.100
regulation of dna metabolic processGO:0051052340.098
regulation of protein metabolic processGO:00512462560.093
Human
mitotic cell cycle checkpointGO:0007093880.088
Human
mitotic sister chromatid segregationGO:0000070870.087
positive regulation of dna endoreduplicationGO:003287740.084
regulation of transcription from rna polymerase ii promoterGO:00063573780.082
apoptotic processGO:00069151590.082
spindle organizationGO:00070512530.082
mitotic recombinationGO:000631220.080
Human
negative regulation of oskar mrna translationGO:000731950.079
positive regulation of cell cycle processGO:0090068280.077
Human
negative regulation of transpositionGO:0010529120.076
positive regulation of cellular biosynthetic processGO:00313283160.075
negative regulation of mitotic cell cycleGO:00459301090.074
Human
pole plasm assemblyGO:0007315610.073
negative regulation of signal transductionGO:00099682060.071
cell cycle dna replicationGO:0044786230.070
response to light stimulusGO:00094161240.069
negative regulation of cell cycle processGO:00109481090.069
Human
catabolic processGO:00090564090.066
Human
negative regulation of nucleic acid templated transcriptionGO:19035072400.066
gene silencing by rnaGO:0031047570.065
negative regulation of cellular component organizationGO:00511291080.064
Human
ras protein signal transductionGO:0007265880.064
ovarian fusome organizationGO:0030723110.063
meiotic chromosome separationGO:005130780.062
response to caffeineGO:0031000120.062
embryonic pattern specificationGO:00098801740.061
eggshell chorion gene amplificationGO:000730790.060
positive regulation of macromolecule metabolic processGO:00106044050.060
positive regulation of cell cycleGO:0045787430.060
Human
ribose phosphate metabolic processGO:00196931450.059
nucleobase containing small molecule metabolic processGO:00550861740.059
cell maturationGO:00484691440.058
chorion containing eggshell pattern formationGO:0030381110.058
pirna metabolic processGO:0034587100.055
ncrna 3 end processingGO:0043628170.055
deathGO:00162652840.053
cytoplasmic transport nurse cell to oocyteGO:0007303120.053
regulation of response to stressGO:00801342000.052
mitotic nuclear divisionGO:00070672130.052
cell cycle g2 m phase transitionGO:0044839220.052
nucleoside triphosphate catabolic processGO:00091431080.050
negative regulation of rna metabolic processGO:00512532510.049
positive regulation of biosynthetic processGO:00098913160.049
organonitrogen compound metabolic processGO:19015643180.049
response to radiationGO:00093141550.048
dna conformation changeGO:00711031050.048
phosphorylationGO:00163102940.047
actin filament based processGO:00300292200.047
purine ribonucleoside catabolic processGO:00461301120.047
actin filament organizationGO:00070151260.046
sister chromatid cohesionGO:0007062180.045
negative regulation of rna biosynthetic processGO:19026792400.045
programmed cell deathGO:00125012570.044
ribonucleoside catabolic processGO:00424541120.043
purine ribonucleoside metabolic processGO:00461281270.043
regulation of small gtpase mediated signal transductionGO:0051056930.042
ribonucleoside metabolic processGO:00091191270.042
regulation of pole plasm oskar mrna localizationGO:0007317270.040
negative regulation of cellular metabolic processGO:00313243820.040
Human
nucleoside phosphate catabolic processGO:19012921100.039
body morphogenesisGO:001017120.037
regulation of catabolic processGO:00098941700.037
Human
regulation of phosphorus metabolic processGO:00511742100.036
developmental maturationGO:00217001720.035
single organism biosynthetic processGO:00447112060.035
positive regulation of nitrogen compound metabolic processGO:00511733540.035
signal transduction by phosphorylationGO:00230141070.034
single organism cellular localizationGO:19025801800.034
blastoderm segmentationGO:00073501590.033
dna double strand break processingGO:000072930.033
oocyte maturationGO:000155630.033
endocytosisGO:00068973100.032
nucleoside metabolic processGO:00091161270.032
purine ribonucleoside triphosphate metabolic processGO:00092051190.032
targeting of mrna for destruction involved in rna interferenceGO:003042340.031
positive regulation of cellular component organizationGO:00511301560.031
purine containing compound catabolic processGO:00725231120.031
response to organic cyclic compoundGO:0014070890.031
mrna processingGO:00063971040.031
ribonucleoside monophosphate metabolic processGO:0009161510.031
purine containing compound metabolic processGO:00725211550.031
meiotic sister chromatid segregationGO:004514460.030
cellular macromolecular complex assemblyGO:00346221530.030
rna polymerase ii transcriptional preinitiation complex assemblyGO:0051123200.030
chromatin organizationGO:00063252070.029
purine ribonucleoside triphosphate catabolic processGO:00092071080.029
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.028
organelle assemblyGO:00709251980.028
chromatin modificationGO:00165681470.028
positive regulation of signal transductionGO:00099672230.027
positive regulation of signalingGO:00230562430.027
dna amplificationGO:0006277110.027
carbohydrate derivative metabolic processGO:19011352170.027
negative regulation of cellular biosynthetic processGO:00313272770.026
small gtpase mediated signal transductionGO:0007264880.026
protein modification processGO:00362114380.026
single organism catabolic processGO:00447122280.026
vesicle mediated transportGO:00161923810.026
posttranscriptional gene silencingGO:0016441460.026
nucleus localizationGO:0051647340.026
positive regulation of catabolic processGO:00098961050.026
nucleoside phosphate metabolic processGO:00067531620.025
enzyme linked receptor protein signaling pathwayGO:00071671790.025
cell deathGO:00082192790.025
response to camptothecinGO:190156320.025
chromatin remodelingGO:0006338720.025
cytoplasm organizationGO:0007028640.025
organophosphate metabolic processGO:00196371950.025
response to alkaloidGO:0043279260.025
oocyte microtubule cytoskeleton organizationGO:0016325350.024
negative regulation of cell communicationGO:00106482230.024
protein phosphorylationGO:00064681690.024
establishment of oocyte nucleus localization involved in oocyte dorsal ventral axis specificationGO:003072260.024
response to nitrogen compoundGO:1901698900.024
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.024
purine nucleoside monophosphate catabolic processGO:0009128380.023
nuclear dna replicationGO:003326010.023
purine nucleoside metabolic processGO:00422781270.023
purine nucleoside monophosphate metabolic processGO:0009126500.023
medium chain fatty acid metabolic processGO:005179110.023
regulation of meiosisGO:004002030.023
protein dna complex subunit organizationGO:0071824860.022
regulation of organelle organizationGO:00330431960.022
Human
positive regulation of response to stimulusGO:00485843230.022
positive regulation of nuclear transcribed mrna poly a tail shorteningGO:006021340.022
negative regulation of erk1 and erk2 cascadeGO:007037330.022
response to ionizing radiationGO:0010212320.022
regulation of nuclear divisionGO:0051783580.022
Human
purine nucleotide metabolic processGO:00061631460.021
regulation of cytoskeleton organizationGO:0051493890.021
Human
negative regulation of meiotic cell cycleGO:005144720.021
positive regulation of hydrolase activityGO:0051345780.021
sex differentiationGO:0007548810.021
regulation of multicellular organismal developmentGO:20000264140.021
cellular response to radiationGO:0071478520.021
positive regulation of intracellular signal transductionGO:19025331160.021
protein dna complex assemblyGO:0065004630.021
positive regulation of phosphate metabolic processGO:00459371390.020
positive regulation of cellular catabolic processGO:0031331950.020
cellular response to organic substanceGO:00713101320.020
positive regulation of gene expressionGO:00106282900.020
anion homeostasisGO:005508130.020
chaeta morphogenesisGO:0008407420.019
compound eye photoreceptor cell differentiationGO:00017511400.019
positive regulation of mapk cascadeGO:0043410630.019
nucleoside catabolic processGO:00091641120.019
protein complex assemblyGO:00064612000.019
glycosyl compound catabolic processGO:19016581120.019
nucleotide metabolic processGO:00091171610.019
regulation of programmed cell deathGO:00430671520.019
regulation of g2 m transition of mitotic cell cycleGO:0010389150.019
nucleoside triphosphate metabolic processGO:00091411200.018
peptidyl amino acid modificationGO:00181931050.018
embryo development ending in birth or egg hatchingGO:00097921520.018
embryonic axis specificationGO:00005781070.018
regulation of double strand break repairGO:200077930.018
purine nucleoside triphosphate metabolic processGO:00091441190.018
positive regulation of phosphorus metabolic processGO:00105621390.018
ribonucleotide catabolic processGO:00092611090.018
ribonucleoside triphosphate catabolic processGO:00092031080.018
response to endogenous stimulusGO:00097191190.018
posttranscriptional gene silencing by rnaGO:0035194450.017
phagocytosisGO:00069092150.017
regulation of mapk cascadeGO:0043408920.017
response to oxygen containing compoundGO:19017002000.017
purine nucleoside catabolic processGO:00061521120.017
positive regulation of cell cycle phase transitionGO:1901989200.017
erbb signaling pathwayGO:0038127580.017
glycosyl compound metabolic processGO:19016571270.017
regulation of erk1 and erk2 cascadeGO:0070372390.017
chromosome organization involved in meiosisGO:0070192100.017
epidermal growth factor receptor signaling pathwayGO:0007173580.017
ion transportGO:00068111450.017
dna alkylationGO:000630540.017
negative regulation of protein metabolic processGO:0051248850.017
Human
immune responseGO:00069552460.016
organonitrogen compound catabolic processGO:19015651280.016
morphogenesis of follicular epitheliumGO:0016333360.016
chromosome condensationGO:0030261410.016
positive regulation of mrna catabolic processGO:006101450.016
pole plasm rna localizationGO:0007316520.016
negative regulation of gene expressionGO:00106293870.016
Human
polyol biosynthetic processGO:004617330.016
regulation of cellular response to stressGO:0080135890.016
regulation of cellular localizationGO:00603411360.016
intracellular signal transductionGO:00355563000.016
response to decreased oxygen levelsGO:0036293580.016
carbohydrate derivative catabolic processGO:19011361180.016
organophosphate catabolic processGO:00464341120.016
positive regulation of dna metabolic processGO:0051054120.016
regulation of ras protein signal transductionGO:0046578930.016
rna processingGO:00063961470.016
regulation of phosphate metabolic processGO:00192202100.015
rna interferenceGO:0016246270.015
segmentationGO:00352822070.015
macromolecular complex assemblyGO:00650032560.015
regulation of mrna metabolic processGO:1903311720.015
male pronucleus assemblyGO:003503960.015
cell cycle arrestGO:000705040.015
purine ribonucleotide metabolic processGO:00091501450.015
negative regulation of organelle organizationGO:0010639560.015
Human
agingGO:00075681430.015
determination of adult lifespanGO:00083401370.015
purine ribonucleotide catabolic processGO:00091541090.014
establishment or maintenance of cell polarityGO:00071631670.014
dna biosynthetic processGO:0071897240.014
spermatid developmentGO:0007286980.014
regulation of cellular protein metabolic processGO:00322682430.014
Human
tissue morphogenesisGO:00487292970.014
anatomical structure homeostasisGO:0060249970.014
cell motilityGO:00488702510.014
negative regulation of signalingGO:00230572190.014
regulation of catalytic activityGO:00507901850.014
positive regulation of molecular functionGO:00440931360.014
cellular protein modification processGO:00064644380.014
regulation of response to dna damage stimulusGO:2001020230.014
ribonucleotide metabolic processGO:00092591450.013
nucleoside monophosphate metabolic processGO:0009123520.013
histone acetylationGO:0016573380.013
carboxylic acid metabolic processGO:0019752920.013
negative regulation of transcription dna templatedGO:00458922370.013
translesion synthesisGO:001998520.013
positive regulation of protein metabolic processGO:00512471280.013
nucleotide catabolic processGO:00091661090.013
positive regulation of catalytic activityGO:00430851180.013
positive regulation of phosphorylationGO:0042327870.013
negative regulation of biosynthetic processGO:00098902770.013
appendage morphogenesisGO:00351073970.013
cell agingGO:000756920.013
establishment of protein localizationGO:00451841630.013
mrna metabolic processGO:00160711240.013
regulation of apoptotic processGO:00429811300.013
ribonucleoside triphosphate metabolic processGO:00091991190.012
cell proliferationGO:00082832990.012
negative regulation of growthGO:0045926840.012
mapk cascadeGO:00001651070.012
regulation of phosphorylationGO:00423251470.012
anterior posterior axis specification embryoGO:00085951030.012
regulation of cellular catabolic processGO:00313291570.012
Human
reproductive system developmentGO:0061458740.012
negative regulation of intracellular signal transductionGO:1902532570.012
locomotory behaviorGO:00076261760.012
negative regulation of nucleobase containing compound metabolic processGO:00459342610.012
protein complex biogenesisGO:00702712010.012
dna replicationGO:0006260480.012
male meiosis iGO:000714190.012
response to organophosphorusGO:004668320.012
response to oxygen levelsGO:0070482590.012
secondary metabolite catabolic processGO:009048710.012
negative regulation of macromolecule biosynthetic processGO:00105582700.012
dna dependent dna replicationGO:0006261170.012
imaginal disc derived appendage developmentGO:00487373990.011
developmental growthGO:00485892800.011
dna templated transcriptional preinitiation complex assemblyGO:0070897200.011
postreplication repairGO:000630120.011
negative regulation of cellular protein metabolic processGO:0032269850.011
Human
establishment or maintenance of polarity of follicular epitheliumGO:0016334260.011
positive regulation of nuclear transcribed mrna catabolic process deadenylation dependent decayGO:190015340.011
growthGO:00400073590.011
purine ribonucleoside monophosphate catabolic processGO:0009169380.011
striated muscle cell differentiationGO:0051146900.011
meiotic sister chromatid cohesionGO:005117760.011
positive regulation of developmental processGO:00510941430.011
positive regulation of g2 m transition of mitotic cell cycleGO:001097120.011
neurological system processGO:00508773580.011
signal transduction in response to dna damageGO:004277030.011
regulation of mrna processingGO:0050684710.011
positive regulation of cell developmentGO:0010720610.011
positive regulation of cell communicationGO:00106472500.011
positive regulation of nucleic acid templated transcriptionGO:19035082660.011
telomere maintenanceGO:0000723210.011
response to uvGO:0009411240.011
immune response regulating signaling pathwayGO:000276420.011
positive regulation of multicellular organismal processGO:00512401430.011
protein localizationGO:00081042840.011
response to inorganic substanceGO:0010035440.011
oxoacid metabolic processGO:00434361030.011
tripartite regional subdivisionGO:00073511030.011
spinal cord patterningGO:002151110.011
ribonucleoside monophosphate catabolic processGO:0009158390.010
regulation of growthGO:00400082330.010
regulation of cell morphogenesisGO:00226041630.010
purine nucleotide catabolic processGO:00061951090.010
cellular response to ionizing radiationGO:0071479150.010
positive regulation of cellular protein metabolic processGO:00322701180.010
positive regulation of ras protein signal transductionGO:0046579430.010
purine nucleoside triphosphate catabolic processGO:00091461080.010
synaptic transmissionGO:00072682880.010
response to other organismGO:00517072930.010
female germ line cyst formationGO:0048135420.010

spn-B disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.273
bone marrow diseaseDOID:496100.273
anemiaDOID:235500.273
aplastic anemiaDOID:1244900.273
hematopoietic system diseaseDOID:7400.273
immune system diseaseDOID:291400.273
congenital hypoplastic anemiaDOID:134200.221
breast cancerDOID:161200.069
Human
thoracic cancerDOID:509300.069
Human
disease of cellular proliferationDOID:1456600.069
Human
cancerDOID:16200.069
Human
organ system cancerDOID:005068600.069
Human
cardiovascular system diseaseDOID:128700.026
hypertensionDOID:1076300.026
essential hypertensionDOID:1082500.026
artery diseaseDOID:005082800.026
vascular diseaseDOID:17800.026
glucose metabolism diseaseDOID:419400.015
acquired metabolic diseaseDOID:006015800.015
disease of metabolismDOID:001466700.015
carbohydrate metabolism diseaseDOID:005001300.015