Drosophila melanogaster

372 known processes

p53 (Dmel_CG33336)

CG33336 gene product from transcript CG33336-RB

(Aliases: Dmel\CG33336,Dm-P53,dmp53,CG10873,D-p53,DmP53,prac,Dp53,Dmp53,CG33336,dp53,CG31325)

p53 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
dna metabolic processGO:00062592270.999
negative regulation of cell cycleGO:00457861160.997
Human Zebrafish Mouse
intrinsic apoptotic signaling pathwayGO:0097193160.996
negative regulation of cell cycle phase transitionGO:19019881030.995
Human Mouse
chromosome organizationGO:00512763600.994
Human Mouse
negative regulation of nitrogen compound metabolic processGO:00511722650.993
Human Zebrafish Mouse
cellular response to dna damage stimulusGO:00069742230.991
apoptotic signaling pathwayGO:0097190270.991
cellular protein modification processGO:00064644380.985
Mouse
positive regulation of nitrogen compound metabolic processGO:00511733540.984
negative regulation of transcription dna templatedGO:00458922370.984
Human Zebrafish Mouse
epithelial cell developmentGO:00020642740.982
Mouse
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630110.977
negative regulation of cellular biosynthetic processGO:00313272770.977
Human Zebrafish Mouse
response to radiationGO:00093141550.970
negative regulation of nucleobase containing compound metabolic processGO:00459342610.967
Human Zebrafish Mouse
mitotic cell cycle phase transitionGO:00447721380.960
Human Mouse
negative regulation of mitotic cell cycleGO:00459301090.959
Human Mouse
negative regulation of cellular metabolic processGO:00313243820.954
response to organic substanceGO:00100332840.950
Zebrafish Mouse
programmed cell deathGO:00125012570.945
double strand break repairGO:0006302260.944
Mouse
regulation of cell cycle phase transitionGO:19019871300.936
Human Mouse
negative regulation of cell cycle processGO:00109481090.928
Human Mouse
regulation of cell cycleGO:00517262910.927
mitotic cell cycle checkpointGO:0007093880.923
Human Mouse
mitotic dna damage checkpointGO:0044773740.920
Human Mouse
regulation of endopeptidase activityGO:0052548360.912
regulation of mitotic cell cycleGO:00073461900.908
Human Mouse
regulation of protein metabolic processGO:00512462560.899
axonogenesisGO:00074092900.895
embryo development ending in birth or egg hatchingGO:00097921520.893
Zebrafish Mouse Worm
response to abiotic stimulusGO:00096283410.891
negative regulation of rna biosynthetic processGO:19026792400.888
Human Zebrafish Mouse
columnar cuboidal epithelial cell differentiationGO:00020652560.879
Mouse
negative regulation of gene expressionGO:00106293870.875
Human Zebrafish Mouse
neuron deathGO:0070997270.869
Zebrafish Mouse
positive regulation of cellular protein metabolic processGO:00322701180.861
cell growthGO:00160491080.857
Human
cellular response to chemical stimulusGO:00708871990.852
Human Zebrafish Mouse
cellular catabolic processGO:00442483720.852
telomere organizationGO:0032200210.849
regulation of macroautophagyGO:0016241150.842
positive regulation of signal transductionGO:00099672230.841
regulation of gene expression epigeneticGO:00400291280.837
protein phosphorylationGO:00064681690.837
Mouse
axon developmentGO:00615642970.821
dna packagingGO:0006323910.815
Human
catabolic processGO:00090564090.815
positive regulation of macroautophagyGO:001623980.804
meiotic chromosome segregationGO:0045132590.799
Worm
gene silencingGO:00164581380.796
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.795
ectopic germ cell programmed cell deathGO:003523480.789
response to organonitrogen compoundGO:0010243750.785
chromatin organizationGO:00063252070.775
Human Mouse
signal transduction in response to dna damageGO:004277030.773
Human Zebrafish Mouse
negative regulation of rna metabolic processGO:00512532510.772
Human Zebrafish Mouse
negative regulation of mitotic cell cycle phase transitionGO:19019911030.771
Human Mouse
protein modification processGO:00362114380.771
Mouse
response to light stimulusGO:00094161240.769
cell cycle phase transitionGO:00447701400.766
Human Mouse
transcription from rna polymerase ii promoterGO:00063663680.766
cellular response to oxidative stressGO:0034599280.766
Human
regulation of organelle organizationGO:00330431960.744
Human Mouse
chromatin modificationGO:00165681470.740
Mouse
deathGO:00162652840.736
organelle fissionGO:00482853400.731
establishment of localization in cellGO:00516494020.728
immune responseGO:00069552460.726
Mouse
autophagyGO:00069141080.713
mitotic nuclear divisionGO:00070672130.705
negative regulation of neuron deathGO:1901215180.700
Mouse
proteolysisGO:00065081920.697
dna repairGO:0006281540.682
regulation of mitotic cell cycle phase transitionGO:19019901300.682
Human Mouse
positive regulation of rna metabolic processGO:00512542710.668
regulation of cellular response to stressGO:0080135890.666
positive regulation of cysteine type endopeptidase activityGO:2001056240.657
negative regulation of biosynthetic processGO:00098902770.653
Human Zebrafish Mouse
telomere maintenanceGO:0000723210.649
cellular response to abiotic stimulusGO:0071214580.638
mitotic dna integrity checkpointGO:0044774750.638
Human Mouse
positive regulation of macromolecule metabolic processGO:00106044050.634
positive regulation of cellular component organizationGO:00511301560.626
Human Mouse
cellular response to oxygen containing compoundGO:1901701790.624
regulation of multicellular organismal developmentGO:20000264140.623
growthGO:00400073590.622
negative regulation of cell deathGO:0060548810.618
Human Mouse
response to ionizing radiationGO:0010212320.617
cellular response to organic substanceGO:00713101320.613
Mouse
cellular macromolecule catabolic processGO:00442651360.608
histone modificationGO:00165701060.603
Mouse
regulation of cell deathGO:00109411730.590
regulation of phosphorylationGO:00423251470.586
positive regulation of gene expressionGO:00106282900.583
regulation of cell cycle processGO:00105641810.571
Human Mouse
brain developmentGO:00074201200.562
Mouse
dna integrity checkpointGO:0031570810.557
Human Zebrafish Mouse
cell deathGO:00082192790.550
regulation of cell divisionGO:0051302720.547
Zebrafish Mouse
embryonic development via the syncytial blastodermGO:00017001480.544
dna conformation changeGO:00711031050.543
Human
positive regulation of transcription dna templatedGO:00458932660.542
eye morphogenesisGO:00485922600.541
regulation of neuron apoptotic processGO:0043523160.539
Zebrafish Mouse
regulation of neuron deathGO:1901214260.536
Zebrafish Mouse
taxisGO:00423303040.530
organelle localizationGO:00516401480.526
positive regulation of cell communicationGO:00106472500.524
cellular protein catabolic processGO:0044257830.519
regulation of peptidase activityGO:0052547390.515
response to uvGO:0009411240.511
positive regulation of nucleobase containing compound metabolic processGO:00459353320.505
gliogenesisGO:0042063800.503
negative regulation of protein metabolic processGO:0051248850.500
Mouse
macromolecule catabolic processGO:00090571610.497
immune system processGO:00023763470.493
Zebrafish Mouse
negative regulation of gene expression epigeneticGO:0045814770.491
chemotaxisGO:00069352490.488
positive regulation of response to stimulusGO:00485843230.487
anatomical structure homeostasisGO:0060249970.474
Zebrafish
apoptotic processGO:00069151590.473
cell type specific apoptotic processGO:0097285380.467
Human Zebrafish Mouse
regulation of chromosome organizationGO:0033044640.465
Mouse
chromatin silencingGO:0006342760.464
positive regulation of signalingGO:00230562430.463
ovarian follicle cell developmentGO:00307072480.462
eggshell formationGO:00307031050.455
nuclear divisionGO:00002803320.454
regulation of intracellular signal transductionGO:19025312360.453
Human Mouse
homeostatic processGO:00425921990.449
Zebrafish Mouse
regulation of cell differentiationGO:00455953020.447
columnar cuboidal epithelial cell developmentGO:00020662490.429
regulation of cellular protein metabolic processGO:00322682430.427
regulation of catabolic processGO:00098941700.423
chorion containing eggshell formationGO:00073041050.423
negative regulation of response to stimulusGO:00485852580.422
Mouse
negative regulation of nucleic acid templated transcriptionGO:19035072400.413
Human Zebrafish Mouse
developmental growthGO:00485892800.412
meiotic cell cycle processGO:19030461320.398
phosphorylationGO:00163102940.379
cell cycle checkpointGO:0000075950.374
Human Zebrafish Mouse
positive regulation of endopeptidase activityGO:0010950260.373
negative regulation of intracellular signal transductionGO:1902532570.372
Mouse
compound eye developmentGO:00487493070.372
regulation of transferase activityGO:0051338580.368
cell cycle arrestGO:000705040.368
Human Mouse
regulation of proteolysisGO:0030162870.366
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281250.363
negative regulation of cell communicationGO:00106482230.363
Mouse
regulation of cysteine type endopeptidase activityGO:2000116270.356
cellular response to ionizing radiationGO:0071479150.353
regulation of response to extracellular stimulusGO:0032104180.349
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.346
Human Zebrafish Mouse
intrinsic apoptotic signaling pathway by p53 class mediatorGO:007233250.345
double strand break repair via homologous recombinationGO:0000724130.341
dna damage checkpointGO:0000077780.331
Human Zebrafish Mouse
regulation of mitosisGO:0007088560.327
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stressGO:007005940.326
Zebrafish
spindle organizationGO:00070512530.322
regulation of phosphorus metabolic processGO:00511742100.316
positive regulation of organelle organizationGO:0010638650.308
Human Mouse
organic substance catabolic processGO:19015753080.308
axon guidanceGO:00074112330.306
innate immune responseGO:00450871440.305
negative regulation of macromolecule biosynthetic processGO:00105582700.305
Human Zebrafish Mouse
regulation of cellular catabolic processGO:00313291570.304
cellular response to nutrient levelsGO:0031669620.304
nucleoside triphosphate catabolic processGO:00091431080.302
germ cell migrationGO:0008354430.301
translationGO:0006412690.299
positive regulation of rna biosynthetic processGO:19026802660.298
positive regulation of proteolysisGO:0045862520.291
developmental growth involved in morphogenesisGO:0060560650.289
regulation of dna metabolic processGO:0051052340.289
regulation of cell proliferationGO:00421271630.287
mitotic g2 dna damage checkpointGO:0007095690.286
cell motilityGO:00488702510.284
recombinational repairGO:0000725130.280
positive regulation of response to extracellular stimulusGO:003210680.280
central nervous system developmentGO:00074172010.279
Zebrafish Mouse
negative regulation of organelle organizationGO:0010639560.273
modification dependent protein catabolic processGO:0019941780.272
regionalizationGO:00030024160.268
Mouse
cellular response to starvationGO:0009267610.266
cellular response to gamma radiationGO:0071480100.264
regulation of cell cycle g1 s phase transitionGO:1902806230.262
Human Mouse
negative regulation of phosphorylationGO:0042326350.260
positive regulation of peptidase activityGO:0010952290.252
negative regulation of catalytic activityGO:0043086420.249
response to oxidative stressGO:0006979860.249
Human Mouse Worm
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161540.246
cellular response to external stimulusGO:0071496660.243
protein catabolic processGO:00301631010.240
neuron apoptotic processGO:0051402170.238
Zebrafish Mouse
dendrite morphogenesisGO:00488131990.235
response to nitrogen compoundGO:1901698900.234
cell migrationGO:00164772380.232
regulation of response to stressGO:00801342000.227
regulation of translationGO:0006417560.224
centrosome cycleGO:00070981370.223
eye developmentGO:00016543230.223
telomere cappingGO:0016233110.223
positive regulation of protein metabolic processGO:00512471280.220
defense responseGO:00069523000.219
Mouse
multicellular organismal agingGO:00102591400.218
dorsal closureGO:0007391790.216
regulation of transportGO:00510491810.216
negative regulation of programmed cell deathGO:0043069720.206
Human Mouse
dendrite developmentGO:00163582040.206
negative regulation of cellular component organizationGO:00511291080.204
positive regulation of cell deathGO:0010942690.198
locomotory behaviorGO:00076261760.195
cell proliferationGO:00082832990.194
positive regulation of cellular biosynthetic processGO:00313283160.193
epithelial cell differentiationGO:00308553220.191
Mouse
regulation of phosphate metabolic processGO:00192202100.189
chromosome segregationGO:00070591570.186
Worm
vesicle mediated transportGO:00161923810.185
response to oxygen containing compoundGO:19017002000.184
regulation of proteasomal protein catabolic processGO:0061136390.182
regulation of developmental growthGO:00486381740.181
regulation of catalytic activityGO:00507901850.179
neuron projection guidanceGO:00974852410.178
negative regulation of transferase activityGO:0051348180.177
positive regulation of developmental processGO:00510941430.177
apoptotic process involved in developmentGO:1902742200.176
sensory organ morphogenesisGO:00905962600.174
organ growthGO:0035265560.174
cellular response to radiationGO:0071478520.172
pigmentationGO:0043473750.171
positive regulation of phosphorylationGO:0042327870.171
Mouse
positive regulation of response to nutrient levelsGO:003210980.167
negative regulation of signalingGO:00230572190.167
Mouse
protein complex assemblyGO:00064612000.165
Human
dna recombinationGO:0006310320.165
agingGO:00075681430.162
extrinsic apoptotic signaling pathwayGO:009719110.161
response to x rayGO:001016580.161
execution phase of apoptosisGO:009719470.158
protein modification by small protein conjugation or removalGO:00706471060.158
meiotic nuclear divisionGO:00071261510.158
localization of cellGO:00516742570.157
regulation of protein kinase activityGO:0045859510.157
Mouse
negative regulation of cell cycle g1 s phase transitionGO:1902807130.156
Human Mouse
negative regulation of neuron apoptotic processGO:0043524140.155
Mouse
negative regulation of apoptotic processGO:0043066630.153
Human Mouse
microtubule organizing center organizationGO:00310231680.148
regulation of anatomical structure sizeGO:00900661630.145
Mouse
mitotic spindle organizationGO:00070522200.144
regulation of cell growthGO:0001558430.144
Human
stress activated mapk cascadeGO:0051403520.142
Mouse
developmental programmed cell deathGO:00106231380.142
regulation of response to nutrient levelsGO:0032107180.137
g2 dna damage checkpointGO:0031572690.137
regulation of apoptotic processGO:00429811300.137
response to inorganic substanceGO:0010035440.135
ubiquitin dependent protein catabolic processGO:0006511780.135
regulation of transcription from rna polymerase ii promoterGO:00063573780.134
negative regulation of phosphorus metabolic processGO:0010563450.134
compound eye morphogenesisGO:00017452490.132
cellular amide metabolic processGO:0043603800.131
regulation of autophagyGO:0010506620.131
development of primary sexual characteristicsGO:0045137500.131
protein modification by small protein conjugationGO:0032446790.130
positive regulation of macromolecule biosynthetic processGO:00105572830.129
developmental pigmentationGO:0048066680.128
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280230.128
regulation of nuclear divisionGO:0051783580.128
negative regulation of signal transductionGO:00099682060.128
Mouse
positive regulation of phosphate metabolic processGO:00459371390.126
Mouse
immune response regulating signaling pathwayGO:000276420.123
dna double strand break processingGO:000072930.122
regulation of protein phosphorylationGO:0001932640.121
Mouse
regulation of innate immune responseGO:0045088710.120
regulation of epithelial cell proliferationGO:005067840.119
Mouse
regulation of apoptotic signaling pathwayGO:2001233100.119
Human Mouse
proteasomal protein catabolic processGO:0010498590.118
regulation of wnt signaling pathwayGO:0030111680.117
protein localizationGO:00081042840.116
jnk cascadeGO:0007254500.114
Mouse
response to endogenous stimulusGO:00097191190.114
Mouse
regulation of growthGO:00400082330.113
canonical wnt signaling pathwayGO:0060070210.112
establishment or maintenance of cell polarityGO:00071631670.112
cellular component assembly involved in morphogenesisGO:00109271510.111
dna biosynthetic processGO:0071897240.110
eggshell chorion assemblyGO:0007306660.109
heterocycle catabolic processGO:00467001660.108
centrosome organizationGO:00512971630.104
regulation of molecular functionGO:00650092170.101
proteolysis involved in cellular protein catabolic processGO:0051603830.101
spermatogenesisGO:00072832000.100
Zebrafish
regulation of immune responseGO:00507761180.099
negative regulation of cellular response to oxidative stressGO:190040810.098
photoreceptor cell differentiationGO:00465301700.098
signal transduction by p53 class mediatorGO:007233160.098
cellular nitrogen compound catabolic processGO:00442701650.096
enzyme linked receptor protein signaling pathwayGO:00071671790.095
negative regulation of kinase activityGO:0033673160.094
modification dependent macromolecule catabolic processGO:0043632790.094
cellular response to organonitrogen compoundGO:0071417360.094
ribonucleoside triphosphate catabolic processGO:00092031080.094
neurological system processGO:00508773580.094
positive regulation of biosynthetic processGO:00098913160.092
regulation of anatomical structure morphogenesisGO:00226032420.091
Zebrafish
regulation of chromatin organizationGO:1902275320.089
Mouse
small molecule metabolic processGO:00442813050.088
defense response to other organismGO:00985422250.088
regulation of cellular protein catabolic processGO:1903362440.086
negative regulation of cellular protein metabolic processGO:0032269850.086
Mouse
regulation of nervous system developmentGO:00519602480.086
protein complex biogenesisGO:00702712010.085
Human
response to alkaloidGO:0043279260.085
positive regulation of apoptotic processGO:0043065470.084
rna splicingGO:0008380830.083
chromatin remodelingGO:0006338720.082
Mouse
negative regulation of g1 s transition of mitotic cell cycleGO:2000134130.081
Human Mouse
oxoacid metabolic processGO:00434361030.081
camera type eye developmentGO:004301040.080
regulation of stress activated protein kinase signaling cascadeGO:0070302420.080
Mouse
posttranscriptional regulation of gene expressionGO:00106081450.078
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434370.078
covalent chromatin modificationGO:00165691060.078
Mouse
compound eye retinal cell programmed cell deathGO:0046667230.078
single organism behaviorGO:00447083910.078
positive regulation of neuron apoptotic processGO:004352510.078
Zebrafish Mouse
negative regulation of multicellular organismal processGO:00512411420.077
aromatic compound catabolic processGO:00194391660.076
nucleobase containing compound catabolic processGO:00346551650.076
regulation of programmed cell deathGO:00430671520.075
response to alcoholGO:0097305950.075
protein acetylationGO:0006473390.075
determination of adult lifespanGO:00083401370.073
mitotic sister chromatid segregationGO:0000070870.073
regulation of localizationGO:00328792750.072
sister chromatid segregationGO:0000819920.072
protein ubiquitinationGO:0016567700.072
regulation of execution phase of apoptosisGO:190011750.071
morphogenesis of embryonic epitheliumGO:0016331940.071
Mouse
regulation of response to biotic stimulusGO:0002831630.071
endocytosisGO:00068973100.071
response to starvationGO:0042594970.071
signal transduction by phosphorylationGO:00230141070.071
Mouse
regulation of jnk cascadeGO:0046328400.071
Mouse
double strand break repair via synthesis dependent strand annealingGO:004500360.070
mitochondrion organizationGO:0007005650.068
Human Mouse
ribose phosphate metabolic processGO:00196931450.068
regulation of cellular ketone metabolic processGO:001056530.068
reproductive system developmentGO:0061458740.067
Mouse
cellular response to endogenous stimulusGO:0071495800.067
Mouse
positive regulation of protein modification processGO:0031401580.066
Mouse
sex differentiationGO:0007548810.066
Mouse
phenol containing compound metabolic processGO:0018958570.065
regulation of proteolysis involved in cellular protein catabolic processGO:1903050440.065
positive regulation of nucleic acid templated transcriptionGO:19035082660.065
positive regulation of intracellular signal transductionGO:19025331160.064
Human Mouse
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178650.063
Mouse
intracellular signal transductionGO:00355563000.063
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.062
Human Mouse
tube morphogenesisGO:00352391910.062
Mouse
regulation of response to external stimulusGO:00321011150.062
regulation of organ morphogenesisGO:2000027780.062
regulation of protein modification processGO:00313991120.062
Mouse
production of molecular mediator of immune responseGO:0002440460.061
response to superoxideGO:000030330.061
stress activated protein kinase signaling cascadeGO:0031098550.060
Mouse
positive regulation of catabolic processGO:00098961050.060
purine nucleoside triphosphate catabolic processGO:00091461080.060
purine nucleoside catabolic processGO:00061521120.060
organonitrogen compound metabolic processGO:19015643180.060
positive regulation of molecular functionGO:00440931360.060
g1 s transition of mitotic cell cycleGO:0000082310.060
Human Mouse
organic acid metabolic processGO:00060821030.059
positive regulation of execution phase of apoptosisGO:190011940.059
cell divisionGO:00513012480.058
Zebrafish Mouse
positive regulation of catalytic activityGO:00430851180.058
cellular response to reactive oxygen speciesGO:0034614140.058
regulation of cellular amino acid metabolic processGO:000652100.057
cellular response to nitrogen compoundGO:1901699510.057
histolysisGO:00075591020.056
response to organic cyclic compoundGO:0014070890.056
rna processingGO:00063961470.055
positive regulation of cell differentiationGO:0045597640.055
negative regulation of neurogenesisGO:0050768530.054
response to oxygen radicalGO:000030530.054
response to decreased oxygen levelsGO:0036293580.053
Human Zebrafish Worm
regulation of hydrolase activityGO:0051336970.053
ribonucleotide metabolic processGO:00092591450.052
response to purine containing compoundGO:0014074120.052
regulation of cytoskeleton organizationGO:0051493890.052
nuclear migrationGO:0007097200.051
kidney developmentGO:000182230.051
protein heterooligomerizationGO:005129140.051
secretionGO:00469031090.051
Mouse
regulation of protein catabolic processGO:0042176550.049
positive regulation of transferase activityGO:0051347260.049
neural precursor cell proliferationGO:0061351750.049
compound eye photoreceptor developmentGO:0042051780.049
cellular amine metabolic processGO:0044106120.049
regulation of cell sizeGO:0008361630.048
Mouse
negative regulation of molecular functionGO:0044092510.048
transforming growth factor beta receptor signaling pathwayGO:0007179160.048
Mouse
gonad developmentGO:0008406500.047
regulation of kinase activityGO:0043549530.047
cell fate specificationGO:0001708710.047
secretion by cellGO:00329401010.047
regulation of protein stabilityGO:0031647430.047
response to nutrient levelsGO:00316671140.046
positive regulation of autophagyGO:0010508210.045
positive regulation of protein phosphorylationGO:0001934340.045
Mouse
purine nucleotide catabolic processGO:00061951090.045
tube developmentGO:00352952440.044
Mouse
digestive tract morphogenesisGO:00485461270.044
Mouse
carboxylic acid metabolic processGO:0019752920.044
ribonucleoside metabolic processGO:00091191270.044
cellular response to insulin stimulusGO:0032869280.044
regulation of immune system processGO:00026821760.043
positive regulation of growthGO:0045927750.043
response to hypoxiaGO:0001666530.043
Human Zebrafish Worm
negative regulation of protein phosphorylationGO:0001933170.043
Mouse
wnt signaling pathwayGO:0016055980.043
cellular macromolecular complex assemblyGO:00346221530.043
embryonic pattern specificationGO:00098801740.043
regulation of gene silencingGO:0060968630.042
cellular ketone metabolic processGO:0042180240.042
cellular response to extracellular stimulusGO:0031668640.042
mitotic g2 m transition checkpointGO:0044818700.042
glial cell migrationGO:0008347310.042
response to transforming growth factor betaGO:0071559180.042
Mouse
imaginal disc derived wing morphogenesisGO:00074763370.042
regulation of mitotic sister chromatid separationGO:0010965280.041
regulation of cell developmentGO:00602842150.041
organic cyclic compound catabolic processGO:19013611680.041
regulation of protein transportGO:0051223570.040
activation of cysteine type endopeptidase activityGO:0097202170.040
chemical homeostasisGO:0048878920.039
Mouse
rhythmic processGO:00485111060.039
multi organism behaviorGO:00517051750.039
negative regulation of chromosome segregationGO:0051985140.039
respiratory system developmentGO:00605412130.039
dorsal appendage formationGO:0046843470.038
mitochondrial fusionGO:000805370.038
positive regulation of hydrolase activityGO:0051345780.037
response to drugGO:0042493170.037
Human Mouse
compound eye photoreceptor cell differentiationGO:00017511400.037
posttranscriptional gene silencingGO:0016441460.037
response to extracellular stimulusGO:00099911160.037
g2 m transition of mitotic cell cycleGO:0000086190.037
posttranscriptional gene silencing by rnaGO:0035194450.037
regulation of cellular response to oxidative stressGO:190040740.036
dna replicationGO:0006260480.036
Mouse
negative regulation of protein modification processGO:0031400290.036
Mouse
germarium derived oocyte fate determinationGO:0007294260.036
mitotic cell cycle embryonicGO:0045448380.036
cellular response to organic cyclic compoundGO:0071407320.035
nucleotide excision repairGO:000628980.035
Human
digestive system developmentGO:00551231490.035
Mouse
regulation of stress activated mapk cascadeGO:0032872410.035
Mouse
purine nucleoside metabolic processGO:00422781270.035
negative regulation of response to oxidative stressGO:190288310.034
purine ribonucleoside triphosphate catabolic processGO:00092071080.034
spermatid developmentGO:0007286980.034
response to gamma radiationGO:0010332170.033
response to bacteriumGO:00096171980.033
purine ribonucleoside triphosphate metabolic processGO:00092051190.033
tripartite regional subdivisionGO:00073511030.033
telencephalon developmentGO:002153720.032
Mouse
regulation of reactive oxygen species metabolic processGO:200037780.032
Human Mouse
negative regulation of apoptotic signaling pathwayGO:200123450.032
single organism cell adhesionGO:0098602470.032
axis specificationGO:00097981670.032
negative regulation of immune system processGO:0002683500.032
reactive oxygen species metabolic processGO:0072593220.032
Human Mouse
secondary metabolic processGO:0019748750.032
regulation of photoreceptor cell differentiationGO:0046532340.032
developmental maturationGO:00217001720.032
positive regulation of wnt signaling pathwayGO:0030177250.031
positive regulation of insulin receptor signaling pathwayGO:004662830.031
protein autophosphorylationGO:0046777150.031
response to lipidGO:0033993380.031
cell adhesionGO:00071551360.031
response to hormoneGO:0009725450.031
response to acid chemicalGO:0001101250.030
response to other organismGO:00517072930.030
regulation of epithelial cell differentiationGO:003085640.030
Mouse
appendage developmentGO:00487364010.030
Mouse
cellular macromolecule localizationGO:00707272200.030

p53 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.120
thoracic cancerDOID:509300.087
Human
organ system cancerDOID:005068600.087
Human
cancerDOID:16200.087
Human
disease of cellular proliferationDOID:1456600.087
Human
breast cancerDOID:161200.047
Human