Drosophila melanogaster

37 known processes

Uch-L3 (Dmel_CG3431)

Ubiquitin C-terminal hydrolase

(Aliases: uch-L3,l(3)j2B8,CG3431,Dmel\CG3431,dUCH37,BcDNA:LD24440,p37A,BcDNA.LD24440,UCH)

Uch-L3 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
protein modification processGO:00362114380.585
regulation of gene expression epigeneticGO:00400291280.475
regulation of neurogenesisGO:00507671580.345
modification dependent macromolecule catabolic processGO:0043632790.330
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052240.316
protein modification by small protein conjugation or removalGO:00706471060.311
cellular protein modification processGO:00064644380.310
positive regulation of nitrogen compound metabolic processGO:00511733540.306
dendrite developmentGO:00163582040.285
cellular protein catabolic processGO:0044257830.231
negative regulation of neuroblast proliferationGO:0007406270.217
positive regulation of biosynthetic processGO:00098913160.198
positive regulation of rna metabolic processGO:00512542710.191
positive regulation of transcription dna templatedGO:00458932660.186
sensory perceptionGO:00076001960.181
positive regulation of gene expressionGO:00106282900.180
mitotic cell cycle checkpointGO:0007093880.174
positive regulation of nucleic acid templated transcriptionGO:19035082660.171
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.158
intracellular signal transductionGO:00355563000.149
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161540.147
positive regulation of nucleobase containing compound metabolic processGO:00459353320.144
positive regulation of proteasomal protein catabolic processGO:1901800200.141
dendrite morphogenesisGO:00488131990.138
chromosome organizationGO:00512763600.137
protein modification by small protein removalGO:0070646280.128
tissue deathGO:00162711020.114
mrna splice site selectionGO:000637610.111
protein ubiquitinationGO:0016567700.108
dna templated transcriptional preinitiation complex assemblyGO:0070897200.108
proteolysisGO:00065081920.105
mitotic sister chromatid segregationGO:0000070870.103
macromolecule catabolic processGO:00090571610.100
ubiquitin dependent protein catabolic processGO:0006511780.099
imaginal disc derived appendage developmentGO:00487373990.098
imaginal disc derived wing morphogenesisGO:00074763370.093
positive regulation of cellular biosynthetic processGO:00313283160.089
mrna metabolic processGO:00160711240.088
compound eye photoreceptor cell differentiationGO:00017511400.083
positive regulation of macromolecule biosynthetic processGO:00105572830.082
rna processingGO:00063961470.080
rna splicingGO:0008380830.078
reproductive structure developmentGO:0048608740.076
ion transportGO:00068111450.074
cullin deneddylationGO:001038830.070
cell deathGO:00082192790.069
cellular macromolecule catabolic processGO:00442651360.068
cellular component assembly involved in morphogenesisGO:00109271510.067
positive regulation of macromolecule metabolic processGO:00106044050.067
mitotic cell cycle phase transitionGO:00447721380.066
appendage morphogenesisGO:00351073970.064
cellular response to dna damage stimulusGO:00069742230.064
negative regulation of nucleic acid templated transcriptionGO:19035072400.063
proteolysis involved in cellular protein catabolic processGO:0051603830.062
positive regulation of rna biosynthetic processGO:19026802660.061
protein catabolic processGO:00301631010.061
gland morphogenesisGO:00226121450.060
modification dependent protein catabolic processGO:0019941780.060
determination of adult lifespanGO:00083401370.056
regulation of neuron differentiationGO:00456641030.056
axon developmentGO:00615642970.056
mrna processingGO:00063971040.055
camera type eye developmentGO:004301040.054
body morphogenesisGO:001017120.053
positive regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032436190.053
imaginal disc derived leg morphogenesisGO:0007480800.053
eye photoreceptor cell differentiationGO:00017541450.052
wing disc morphogenesisGO:00074723440.052
regulation of transcription from rna polymerase ii promoterGO:00063573780.050
mitotic nuclear divisionGO:00070672130.050
small gtpase mediated signal transductionGO:0007264880.049
negative regulation of neurogenesisGO:0050768530.049
negative regulation of rna biosynthetic processGO:19026792400.049
deathGO:00162652840.048
regulation of localizationGO:00328792750.048
sex differentiationGO:0007548810.048
catabolic processGO:00090564090.047
chromatin organizationGO:00063252070.046
regulation of mitotic cell cycle phase transitionGO:19019901300.045
regulation of intracellular signal transductionGO:19025312360.044
regulation of proteasomal protein catabolic processGO:0061136390.044
neuroblast proliferationGO:0007405740.043
mitotic sister chromatid separationGO:0051306300.043
salivary gland morphogenesisGO:00074351450.043
stem cell differentiationGO:00488631170.043
posttranscriptional regulation of gene expressionGO:00106081450.042
imaginal disc derived appendage morphogenesisGO:00351143950.042
sister chromatid segregationGO:0000819920.042
single organism behaviorGO:00447083910.042
regulation of multicellular organismal developmentGO:20000264140.042
myofibril assemblyGO:0030239360.041
macromolecular complex assemblyGO:00650032560.041
regulation of catabolic processGO:00098941700.041
cilium assemblyGO:0042384380.040
posttranscriptional gene silencingGO:0016441460.039
striated muscle myosin thick filament assemblyGO:007168830.039
protein dna complex assemblyGO:0065004630.039
negative regulation of mitotic cell cycle phase transitionGO:19019911030.038
regulation of r7 cell differentiationGO:0045676150.037
regulation of phosphate metabolic processGO:00192202100.037
stem cell proliferationGO:0072089880.037
nuclear divisionGO:00002803320.036
cellular catabolic processGO:00442483720.036
cell proliferationGO:00082832990.036
mitotic spindle organizationGO:00070522200.035
intracellular transportGO:00469072280.035
appendage developmentGO:00487364010.035
regulation of cell cycle processGO:00105641810.035
larval developmentGO:00021641040.034
photoreceptor cell differentiationGO:00465301700.034
response to bacteriumGO:00096171980.034
chromosome segregationGO:00070591570.034
purine ribonucleoside triphosphate metabolic processGO:00092051190.033
regulation of organelle organizationGO:00330431960.033
small molecule metabolic processGO:00442813050.033
neuron projection guidanceGO:00974852410.033
response to ecdysoneGO:0035075340.032
autophagic cell deathGO:0048102830.032
negative regulation of nitrogen compound metabolic processGO:00511722650.032
protein k48 linked ubiquitinationGO:007093630.032
rna interferenceGO:0016246270.032
regulation of mitotic sister chromatid segregationGO:0033047280.032
transcription from rna polymerase ii promoterGO:00063663680.032
response to endogenous stimulusGO:00097191190.032
positive regulation of response to stimulusGO:00485843230.032
cell divisionGO:00513012480.032
gene silencing by rnaGO:0031047570.031
regulation of nervous system developmentGO:00519602480.031
positive regulation of cellular component biogenesisGO:0044089800.031
post embryonic appendage morphogenesisGO:00351203850.031
exocrine system developmentGO:00352721620.031
regulation of mitotic sister chromatid separationGO:0010965280.031
regulation of cell developmentGO:00602842150.031
positive regulation of cellular protein catabolic processGO:1903364240.031
er nucleus signaling pathwayGO:000698490.031
transmembrane transportGO:00550851390.031
regulation of neuron projection developmentGO:0010975690.030
regulation of cellular component biogenesisGO:00440872010.030
regulation of neuroblast proliferationGO:1902692340.030
mitotic g2 m transition checkpointGO:0044818700.030
histolysisGO:00075591020.030
ras protein signal transductionGO:0007265880.029
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.029
chromatin remodelingGO:0006338720.029
salivary gland developmentGO:00074311620.029
positive regulation of signalingGO:00230562430.029
organonitrogen compound metabolic processGO:19015643180.029
neuromuscular synaptic transmissionGO:0007274670.029
negative regulation of stem cell proliferationGO:2000647300.029
cell projection assemblyGO:0030031940.029
organic substance catabolic processGO:19015753080.029
regulation of protein localizationGO:0032880760.029
metaphase anaphase transition of cell cycleGO:0044784280.028
positive regulation of catabolic processGO:00098961050.028
rna splicing via transesterification reactionsGO:0000375730.028
regulation of response to stressGO:00801342000.028
regulation of cellular protein metabolic processGO:00322682430.028
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377730.028
rna polymerase ii transcriptional preinitiation complex assemblyGO:0051123200.028
spindle assembly involved in mitosisGO:0090307500.028
compound eye developmentGO:00487493070.027
gene silencingGO:00164581380.027
regulation of cell cycle phase transitionGO:19019871300.027
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic processGO:0031145300.027
embryo development ending in birth or egg hatchingGO:00097921520.026
signal transduction by phosphorylationGO:00230141070.026
endocytosisGO:00068973100.026
positive regulation of neurogenesisGO:0050769410.026
regulation of phosphorus metabolic processGO:00511742100.026
regulation of cellular amine metabolic processGO:003323830.026
protein modification by small protein conjugationGO:0032446790.026
regulation of molecular functionGO:00650092170.026
induction of programmed cell death by hormonesGO:0035081120.025
cellular macromolecular complex assemblyGO:00346221530.025
purine nucleoside triphosphate metabolic processGO:00091441190.025
regulation of intracellular transportGO:0032386640.025
vesicle mediated transportGO:00161923810.025
dna metabolic processGO:00062592270.024
positive regulation of phosphorus metabolic processGO:00105621390.024
regulation of cellular catabolic processGO:00313291570.024
chromosome separationGO:0051304420.024
salivary gland cell autophagic cell deathGO:0035071830.024
histone h2a acetylationGO:004396810.024
cell cycle phase transitionGO:00447701400.024
regulation of hydrolase activityGO:0051336970.024
neurological system processGO:00508773580.023
ion transmembrane transportGO:00342201220.023
regulation of photoreceptor cell differentiationGO:0046532340.023
chromatin modificationGO:00165681470.023
protein complex biogenesisGO:00702712010.023
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.023
regulation of phosphorylationGO:00423251470.023
embryonic development via the syncytial blastodermGO:00017001480.023
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434370.022
gonad developmentGO:0008406500.022
organelle fissionGO:00482853400.022
regulation of innate immune responseGO:0045088710.022
negative regulation of transcription dna templatedGO:00458922370.022
negative regulation of mitotic cell cycleGO:00459301090.022
negative regulation of gene expressionGO:00106293870.022
positive regulation of cellular catabolic processGO:0031331950.022
histone exchangeGO:0043486210.022
regulation of microtubule based processGO:0032886490.022
regulation of sister chromatid segregationGO:0033045280.021
regulation of dendrite developmentGO:0050773370.021
nuclear migrationGO:0007097200.021
organelle assemblyGO:00709251980.021
compound eye photoreceptor developmentGO:0042051780.021
positive regulation of r7 cell differentiationGO:004567870.020
regulation of mitotic cell cycleGO:00073461900.020
eye morphogenesisGO:00485922600.020
regulation of defense responseGO:00313471020.020
negative regulation of nucleobase containing compound metabolic processGO:00459342610.020
adult behaviorGO:00305341370.020
mrna cis splicing via spliceosomeGO:004529210.020
positive regulation of cellular protein metabolic processGO:00322701180.019
proteasomal protein catabolic processGO:0010498590.019
reproductive system developmentGO:0061458740.019
nucleus localizationGO:0051647340.019
gliogenesisGO:0042063800.019
dosage compensationGO:0007549160.018
establishment of nucleus localizationGO:0040023260.018
developmental programmed cell deathGO:00106231380.018
axonogenesisGO:00074092900.018
negative regulation of cellular metabolic processGO:00313243820.018
rna localizationGO:00064031150.018
negative regulation of cell cycle phase transitionGO:19019881030.018
cellular nitrogen compound catabolic processGO:00442701650.018
eye developmentGO:00016543230.018
positive regulation of protein metabolic processGO:00512471280.017
positive regulation of cellular amino acid metabolic processGO:004576400.017
regulation of chromosome organizationGO:0033044640.017
regulation of protein metabolic processGO:00512462560.017
regionalizationGO:00030024160.017
regulation of cytoplasmic transportGO:1903649470.017
protein deneddylationGO:000033880.017
regulation of gene silencingGO:0060968630.017
establishment of organelle localizationGO:00516561220.016
protein deubiquitinationGO:0016579170.016
metaphase anaphase transition of mitotic cell cycleGO:0007091280.016
positive regulation of proteolysisGO:0045862520.016
spindle organizationGO:00070512530.016
regulation of chromosome segregationGO:0051983320.016
innate immune responseGO:00450871440.016
spliceosomal snrnp assemblyGO:000038720.016
regulation of mitotic metaphase anaphase transitionGO:0030071260.016
imaginal disc derived leg segmentationGO:0036011260.016
lateral inhibitionGO:00463312060.016
aromatic compound catabolic processGO:00194391660.016
positive regulation of metaphase anaphase transition of cell cycleGO:1902101100.016
rhabdomere developmentGO:0042052380.016
inorganic ion transmembrane transportGO:0098660730.016
regulation of intracellular protein transportGO:0033157460.016
ubiquitin homeostasisGO:001099210.015
response to ketoneGO:1901654340.015
programmed cell deathGO:00125012570.015
organic cyclic compound catabolic processGO:19013611680.015
regulation of meiosisGO:004002030.015
negative regulation of biosynthetic processGO:00098902770.015
negative regulation of meiotic cell cycleGO:005144720.015
regulation of cellular amino acid metabolic processGO:000652100.015
regulation of cell cycleGO:00517262910.015
negative regulation of cell differentiationGO:00455961430.015
defense response to other organismGO:00985422250.015
lipid localizationGO:0010876540.015
protein neddylationGO:004511650.015
regulation of wnt signaling pathwayGO:0030111680.015
mitotic dna damage checkpointGO:0044773740.015
carbohydrate derivative catabolic processGO:19011361180.015
locomotory behaviorGO:00076261760.014
phagocytosisGO:00069092150.014
g2 dna damage checkpointGO:0031572690.014
protein complex assemblyGO:00064612000.014
negative regulation of cell developmentGO:0010721620.014
negative regulation of cell communicationGO:00106482230.014
dna damage checkpointGO:0000077780.014
dendrite guidanceGO:0070983210.014
positive regulation of phosphate metabolic processGO:00459371390.014
posttranscriptional gene silencing by rnaGO:0035194450.014
stem cell developmentGO:0048864790.014
response to endoplasmic reticulum stressGO:0034976280.014
negative regulation of cellular biosynthetic processGO:00313272770.014
dna templated transcription elongationGO:0006354180.014
single organism catabolic processGO:00447122280.014
nucleoside phosphate catabolic processGO:19012921100.013
organophosphate metabolic processGO:00196371950.013
regulation of stem cell proliferationGO:0072091400.013
negative regulation of cellular catabolic processGO:0031330340.013
purine nucleotide metabolic processGO:00061631460.013
regulation of small gtpase mediated signal transductionGO:0051056930.013
spinal cord developmentGO:002151010.013
homeostatic processGO:00425921990.013
response to alcoholGO:0097305950.013
development of primary sexual characteristicsGO:0045137500.013
regulation of chromatin silencingGO:0031935360.013
developmental maturationGO:00217001720.013
regulation of establishment of protein localizationGO:0070201610.013
sensory organ morphogenesisGO:00905962600.013
mitotic cytokinesisGO:0000281500.013
regulation of mrna processingGO:0050684710.013
dna templated transcription initiationGO:0006352250.013
entry into cell of other organism involved in symbiotic interactionGO:005180630.013
cilium morphogenesisGO:0060271390.013
establishment or maintenance of microtubule cytoskeleton polarityGO:0030951410.012
regulation of synapse organizationGO:00508071100.012
regulation of transportGO:00510491810.012
regulation of cell divisionGO:0051302720.012
heterocycle catabolic processGO:00467001660.012
regulation of proteolysis involved in cellular protein catabolic processGO:1903050440.012
regulation of protein modification processGO:00313991120.012
regulation of cell proliferationGO:00421271630.012
ribonucleoside triphosphate metabolic processGO:00091991190.012
regulation of proteolysisGO:0030162870.012
nucleoside phosphate metabolic processGO:00067531620.012
regulation of cellular localizationGO:00603411360.012
nitrogen compound transportGO:0071705850.012
negative regulation of cell cycle processGO:00109481090.012
nucleobase containing small molecule metabolic processGO:00550861740.012
histone h4 k20 methylationGO:003477040.012
negative regulation of gene expression epigeneticGO:0045814770.012
compound eye morphogenesisGO:00017452490.012
protein localizationGO:00081042840.012
regulation of alternative mrna splicing via spliceosomeGO:0000381600.012
immune responseGO:00069552460.012
ribonucleotide metabolic processGO:00092591450.012
neuron recognitionGO:00080381010.012
limb developmentGO:006017310.012
response to abiotic stimulusGO:00096283410.011
positive regulation of photoreceptor cell differentiationGO:0046534120.011
agingGO:00075681430.011
establishment of cell polarityGO:0030010400.011
regulation of mrna metabolic processGO:1903311720.011
chromatin silencingGO:0006342760.011
establishment of localization in cellGO:00516494020.011
regulation of nuclear divisionGO:0051783580.011
negative regulation of neural precursor cell proliferationGO:2000178270.011
establishment of oocyte nucleus localization involved in oocyte dorsal ventral axis specificationGO:003072260.011
regulation of pathway restricted smad protein phosphorylationGO:006039310.011
regulation of protein catabolic processGO:0042176550.011
cellular response to sterol depletionGO:007150130.011
regulation of mapk cascadeGO:0043408920.011
taxisGO:00423303040.011
regulation of ras protein signal transductionGO:0046578930.011
regulation of smoothened signaling pathwayGO:0008589280.011
negative regulation of sequence specific dna binding transcription factor activityGO:004343340.011
chromatin assembly or disassemblyGO:0006333520.010
enzyme linked receptor protein signaling pathwayGO:00071671790.010
regulation of cell differentiationGO:00455953020.010
cytokinetic cell separationGO:000092010.010
synapse organizationGO:00508081960.010
pronuclear migrationGO:003504640.010
atp dependent chromatin remodelingGO:0043044220.010
regulation of metaphase anaphase transition of cell cycleGO:1902099260.010
positive regulation of erk1 and erk2 cascadeGO:0070374360.010
defense responseGO:00069523000.010
regulation of cellular response to growth factor stimulusGO:0090287130.010

Uch-L3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.036
disease of anatomical entityDOID:700.036
sensory system diseaseDOID:005015500.010
central nervous system diseaseDOID:33100.010