Drosophila melanogaster

102 known processes

CycB (Dmel_CG3510)

Cyclin B

(Aliases: cyclinB,cyc-B,cyclin B,cyc B,3510,Cyc B,cycB,Dmel\CG3510,mAbF2F4,2g,CG3510,Cycb,DmcycB,CYCB)

CycB biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
organelle fissionGO:00482853401.000
chromosome segregationGO:00070591571.000
meiotic nuclear divisionGO:00071261511.000
Yeast
nuclear divisionGO:00002803321.000
cell divisionGO:00513012481.000
sister chromatid segregationGO:0000819920.999
dna conformation changeGO:00711031050.998
Mouse Rat
mitotic nuclear divisionGO:00070672130.998
meiotic cell cycleGO:00513211710.998
Yeast
meiotic cell cycle processGO:19030461320.994
Yeast
negative regulation of cellular metabolic processGO:00313243820.989
Yeast Rat
negative regulation of gene expressionGO:00106293870.984
Rat
mitotic sister chromatid segregationGO:0000070870.982
mitotic spindle organizationGO:00070522200.979
Human Yeast Fly
negative regulation of rna biosynthetic processGO:19026792400.979
mitotic cell cycle embryonicGO:0045448380.973
chromosome condensationGO:0030261410.972
Mouse Rat
regulation of mitotic cell cycleGO:00073461900.970
Human Yeast
oocyte maturationGO:000155630.967
Rat Worm
regulation of cell cycleGO:00517262910.963
regulation of cell cycle processGO:00105641810.952
Human Yeast
spindle organizationGO:00070512530.948
Human Yeast Fly
mitotic sister chromatid separationGO:0051306300.944
negative regulation of nucleobase containing compound metabolic processGO:00459342610.944
negative regulation of macromolecule biosynthetic processGO:00105582700.941
cytokinesisGO:0000910900.939
ubiquitin dependent protein catabolic processGO:0006511780.935
single fertilizationGO:0007338240.929
regulation of cell divisionGO:0051302720.923
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434370.921
mitotic cell cycle phase transitionGO:00447721380.907
Human Yeast
meiotic spindle organizationGO:0000212360.895
chromosome organizationGO:00512763600.894
pronuclear migrationGO:003504640.893
modification dependent protein catabolic processGO:0019941780.889
organelle assemblyGO:00709251980.884
Yeast
regulation of mitotic metaphase anaphase transitionGO:0030071260.884
negative regulation of rna metabolic processGO:00512532510.882
regulation of mitosisGO:0007088560.874
spindle elongationGO:0051231830.848
Yeast
spindle assemblyGO:0051225800.846
Yeast
positive regulation of mitotic cell cycleGO:0045931340.846
Human
oocyte developmentGO:00485991240.837
Rat Worm
oocyte differentiationGO:00099941450.833
Rat Worm
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.831
protein complex biogenesisGO:00702712010.826
Yeast Rat
negative regulation of biosynthetic processGO:00098902770.822
cellular protein catabolic processGO:0044257830.816
proteolysis involved in cellular protein catabolic processGO:0051603830.812
negative regulation of cell cycleGO:00457861160.794
Human
macromolecular complex assemblyGO:00650032560.792
Yeast Rat
regulation of proteasomal protein catabolic processGO:0061136390.785
meiosis iiGO:0007135230.785
meiotic chromosome segregationGO:0045132590.777
attachment of spindle microtubules to kinetochoreGO:000860850.772
dna packagingGO:0006323910.768
Mouse Rat
microtubule anchoringGO:0034453110.765
organelle localizationGO:00516401480.764
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161540.760
regulation of organelle organizationGO:00330431960.758
Human Yeast Rat
modification dependent macromolecule catabolic processGO:0043632790.745
regulation of mitotic sister chromatid separationGO:0010965280.743
maintenance of location in cellGO:0051651280.743
cell cycle comprising mitosis without cytokinesisGO:0033301250.735
negative regulation of cellular biosynthetic processGO:00313272770.726
embryo development ending in birth or egg hatchingGO:00097921520.707
Mouse Worm
protein complex assemblyGO:00064612000.702
Yeast Rat
negative regulation of nitrogen compound metabolic processGO:00511722650.695
regulation of mitotic cell cycle phase transitionGO:19019901300.681
Human
regulation of chromosome segregationGO:0051983320.675
Human
regulation of cellular protein catabolic processGO:1903362440.670
negative regulation of transcription dna templatedGO:00458922370.665
regulation of cyclin dependent protein serine threonine kinase activityGO:000007930.655
Yeast
female meiotic divisionGO:0007143700.637
body morphogenesisGO:001017120.614
dna metabolic processGO:00062592270.613
Yeast Mouse Rat
regulation of cytoskeleton organizationGO:0051493890.608
Human Yeast
chromosome localizationGO:0050000200.608
reproductive system developmentGO:0061458740.599
establishment of chromosome localizationGO:0051303200.586
cellular macromolecule catabolic processGO:00442651360.581
nucleus organizationGO:0006997450.577
regulation of nuclear divisionGO:0051783580.564
regulation of metaphase anaphase transition of cell cycleGO:1902099260.563
positive regulation of cell cycle processGO:0090068280.560
Yeast
negative regulation of mitotic sister chromatid separationGO:2000816130.555
meiosis iGO:0007127590.552
Yeast
protein catabolic processGO:00301631010.551
cellular catabolic processGO:00442483720.540
negative regulation of nucleic acid templated transcriptionGO:19035072400.526
cell cycle dna replicationGO:0044786230.522
Yeast
nucleus localizationGO:0051647340.513
positive regulation of cellular protein metabolic processGO:00322701180.510
Rat Worm
regulation of proteolysis involved in cellular protein catabolic processGO:1903050440.509
establishment or maintenance of cell polarityGO:00071631670.503
positive regulation of cellular biosynthetic processGO:00313283160.499
Yeast
asymmetric cell divisionGO:0008356370.496
fertilizationGO:0009566260.484
regulation of cellular catabolic processGO:00313291570.481
meiotic sister chromatid segregationGO:004514460.472
gene silencingGO:00164581380.455
regulation of mitotic sister chromatid segregationGO:0033047280.455
positive regulation of mitotic cell cycle phase transitionGO:1901992200.454
positive regulation of cellular component organizationGO:00511301560.453
Human Yeast Rat
regulation of cell cycle phase transitionGO:19019871300.450
Human
protein localizationGO:00081042840.449
cytoskeleton dependent cytokinesisGO:0061640810.430
regulation of mitotic spindle organizationGO:006023690.427
Human Yeast
positive regulation of macromolecule metabolic processGO:00106044050.427
Yeast Rat Worm
negative regulation of mitotic cell cycle phase transitionGO:19019911030.426
Human
regulation of protein catabolic processGO:0042176550.421
regulation of microtubule based processGO:0032886490.417
Human Yeast
regulation of localizationGO:00328792750.400
Human
positive regulation of nitrogen compound metabolic processGO:00511733540.396
Yeast Rat
germarium derived egg chamber formationGO:00072931010.387
metaphase anaphase transition of cell cycleGO:0044784280.374
epithelial cell differentiationGO:00308553220.371
negative regulation of mitotic cell cycleGO:00459301090.358
Human
gonad developmentGO:0008406500.353
syncytial blastoderm mitotic cell cycleGO:0035186210.342
positive regulation of multicellular organismal processGO:00512401430.341
Rat
regulation of spindle organizationGO:0090224170.323
Human Yeast
spindle checkpointGO:0031577110.318
Human
regulation of sister chromatid segregationGO:0033045280.316
metaphase anaphase transition of mitotic cell cycleGO:0007091280.310
macromolecule catabolic processGO:00090571610.303
regulation of microtubule cytoskeleton organizationGO:0070507410.299
Human Yeast
cystoblast divisionGO:0007282100.299
chromosome separationGO:0051304420.297
female meiosis iGO:000714480.290
spindle assembly involved in female meiosisGO:0007056140.269
regulation of gene expression epigeneticGO:00400291280.264
maintenance of locationGO:0051235730.258
positive regulation of proteasomal protein catabolic processGO:1901800200.257
negative regulation of protein metabolic processGO:0051248850.257
Yeast Rat
chromosome movement towards spindle poleGO:005130540.256
digestive system developmentGO:00551231490.256
Rat
regulation of cell differentiationGO:00455953020.256
germarium derived female germ line cyst formationGO:0030727420.251
female germ line cyst formationGO:0048135420.251
regulation of proteolysisGO:0030162870.247
establishment of organelle localizationGO:00516561220.246
developmental maturationGO:00217001720.235
Rat Worm
mitotic spindle checkpointGO:0071174110.233
Human
mitotic spindle assembly checkpointGO:0007094110.232
oxoacid metabolic processGO:00434361030.231
positive regulation of chromosome segregationGO:0051984100.231
Human
cellular macromolecule localizationGO:00707272200.228
centrosome cycleGO:00070981370.222
reproductive structure developmentGO:0048608740.222
mitotic spindle elongationGO:0000022810.222
Yeast
positive regulation of proteolysisGO:0045862520.219
regulation of meiosisGO:004002030.217
actin cytoskeleton organizationGO:00300362060.214
spindle assembly involved in meiosisGO:0090306200.211
proteasomal protein catabolic processGO:0010498590.210
negative regulation of mitotic sister chromatid segregationGO:0033048130.203
proteolysisGO:00065081920.201
positive regulation of cell cycleGO:0045787430.200
Human Yeast Mouse
regulation of chromatin bindingGO:003556130.196
spindle assembly involved in mitosisGO:0090307500.195
embryonic morphogenesisGO:00485982060.192
microtubule cytoskeleton organization involved in mitosisGO:1902850520.185
cell maturationGO:00484691440.182
Rat Worm
centrosome organizationGO:00512971630.182
cell cycle phase transitionGO:00447701400.178
Human Yeast
negative regulation of cell divisionGO:0051782170.170
nuclear envelope organizationGO:000699870.169
negative regulation of mitotic metaphase anaphase transitionGO:0045841130.158
positive regulation of cell proliferationGO:0008284470.150
Mouse Rat
regulation of cell proliferationGO:00421271630.144
Mouse Rat
regulation of catabolic processGO:00098941700.141
meiotic cell cycle phase transitionGO:004477140.139
Yeast
regulation of cellular component biogenesisGO:00440872010.137
positive regulation of transportGO:0051050920.134
mitotic chromosome condensationGO:0007076220.130
morphogenesis of an epitheliumGO:00020092760.127
central nervous system developmentGO:00074172010.125
pole cell developmentGO:0007277260.124
establishment of localization in cellGO:00516494020.121
phosphorylationGO:00163102940.120
organic substance transportGO:00717022570.119
negative regulation of cellular component organizationGO:00511291080.116
Human
germ line cyst formationGO:0048134440.115
genitalia developmentGO:0048806260.111
embryonic development via the syncytial blastodermGO:00017001480.110
negative regulation of metaphase anaphase transition of cell cycleGO:1902100130.109
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052240.108
positive regulation of mitotic sister chromatid separationGO:1901970100.106
mitotic cytokinesisGO:0000281500.104
cell proliferationGO:00082832990.103
Mouse Rat
regulation of mitotic cell cycle embryonicGO:0009794110.103
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic processGO:0031145300.102
regulation of cellular protein metabolic processGO:00322682430.098
negative regulation of organelle organizationGO:0010639560.097
Human
negative regulation of cellular protein metabolic processGO:0032269850.097
Yeast Rat
positive regulation of macromolecule biosynthetic processGO:00105572830.096
Yeast
mitotic cell cycle checkpointGO:0007093880.096
Human
response to abiotic stimulusGO:00096283410.095
Rat
apoptotic processGO:00069151590.095
positive regulation of protein metabolic processGO:00512471280.095
Rat Worm
regulation of chromosome organizationGO:0033044640.094
Rat
spindle assembly involved in female meiosis iGO:000705750.092
rna localizationGO:00064031150.090
meiotic cytokinesisGO:0033206330.090
positive regulation of metaphase anaphase transition of cell cycleGO:1902101100.088
posttranscriptional regulation of gene expressionGO:00106081450.086
negative regulation of proteolysisGO:0045861310.086
cell cycle g2 m phase transitionGO:0044839220.083
Yeast
negative regulation of protein catabolic processGO:0042177170.083
ribonucleoprotein complex biogenesisGO:0022613310.083
carboxylic acid metabolic processGO:0019752920.081
negative regulation of sister chromatid segregationGO:0033046130.081
chromosome organization involved in meiosisGO:0070192100.080
g1 s transition of mitotic cell cycleGO:0000082310.080
Yeast
regulation of cell cycle g1 s phase transitionGO:1902806230.080
negative regulation of cell cycle processGO:00109481090.080
Human
positive regulation of response to stimulusGO:00485843230.079
establishment of nucleus localizationGO:0040023260.079
organic acid metabolic processGO:00060821030.077
response to organic substanceGO:00100332840.076
Rat
negative regulation of chromosome segregationGO:0051985140.074
male meiosisGO:0007140520.073
mrna processingGO:00063971040.072
Rat
development of primary sexual characteristicsGO:0045137500.072
positive regulation of signal transductionGO:00099672230.072
positive regulation of cellular catabolic processGO:0031331950.072
cell deathGO:00082192790.068
intracellular protein transportGO:00068861040.068
microtubule organizing center organizationGO:00310231680.067
Yeast
regulation of spindle elongationGO:003288710.066
Yeast
positive regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032436190.066
g2 m transition of mitotic cell cycleGO:0000086190.065
Yeast
regulation of protein complex assemblyGO:0043254420.064
cellular response to organic substanceGO:00713101320.063
Rat
cell migrationGO:00164772380.061
tube developmentGO:00352952440.061
Rat
positive regulation of cellular protein catabolic processGO:1903364240.054
regulation of cellular localizationGO:00603411360.054
Human
positive regulation of signalingGO:00230562430.053
negative regulation of cellular catabolic processGO:0031330340.052
negative regulation of nuclear divisionGO:0051784170.052
regulation of cell developmentGO:00602842150.052
protein localization to organelleGO:0033365820.051
positive regulation of cell communicationGO:00106472500.051
negative regulation of proteasomal protein catabolic processGO:1901799160.050
negative regulation of cell communicationGO:00106482230.050
tissue morphogenesisGO:00487292970.049
establishment of cell polarityGO:0030010400.048
negative regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032435160.047
regulation of multicellular organismal developmentGO:20000264140.047
Rat
single organism catabolic processGO:00447122280.046
regulation of meiotic cell cycleGO:005144590.046
regulation of wnt signaling pathwayGO:0030111680.045
regulation of protein metabolic processGO:00512462560.045
positive regulation of rna metabolic processGO:00512542710.045
Rat
deathGO:00162652840.045
chromatin organizationGO:00063252070.045
Mouse Rat
eye developmentGO:00016543230.044
sex differentiationGO:0007548810.043
multi organism reproductive behaviorGO:00447051210.043
nucleocytoplasmic transportGO:0006913720.042
wnt signaling pathwayGO:0016055980.040
protein targetingGO:0006605640.040
maintenance of protein locationGO:0045185280.040
growthGO:00400073590.039
Mouse Rat
actin filament based processGO:00300292200.039
protein transportGO:00150311550.039
multicellular organismal agingGO:00102591400.038
eye morphogenesisGO:00485922600.038
positive regulation of catabolic processGO:00098961050.037
dendrite morphogenesisGO:00488131990.037
mitotic spindle stabilizationGO:004314860.037
Human
positive regulation of cell cycle phase transitionGO:1901989200.036
protein importGO:0017038550.035
localization of cellGO:00516742570.035
regulation of protein localizationGO:0032880760.034
Human
regulation of intracellular transportGO:0032386640.034
dna replicationGO:0006260480.034
Yeast
oocyte anterior posterior axis specificationGO:0007314720.033
oocyte constructionGO:00073081120.033
organic substance catabolic processGO:19015753080.033
negative regulation of signalingGO:00230572190.033
pole cell formationGO:0007279190.032
synaptonemal complex organizationGO:007019350.032
male gamete generationGO:00482322010.032
Rat
nuclear migrationGO:0007097200.031
stem cell proliferationGO:0072089880.031
catabolic processGO:00090564090.030
positive regulation of gene expressionGO:00106282900.030
Rat
establishment of protein localizationGO:00451841630.030
positive regulation of nucleobase containing compound metabolic processGO:00459353320.030
Yeast Rat
notch signaling pathwayGO:00072191200.030
programmed cell deathGO:00125012570.029
centrosome separationGO:0051299200.029
cellular response to dna damage stimulusGO:00069742230.029
cell cycle g1 s phase transitionGO:0044843310.029
Yeast
nuclear transportGO:0051169720.029
determination of adult lifespanGO:00083401370.028
chromatin silencingGO:0006342760.027
regulation of nucleocytoplasmic transportGO:0046822350.027
cell motilityGO:00488702510.027
appendage developmentGO:00487364010.027
regulation of cellular ketone metabolic processGO:001056530.026
negative regulation of meiotic cell cycleGO:005144720.026
regulation of phosphorus metabolic processGO:00511742100.026
regulation of transportGO:00510491810.026
maintenance of protein location in cellGO:0032507260.025
chromatin assembly or disassemblyGO:0006333520.025
neurological system processGO:00508773580.025
establishment of spindle orientationGO:0051294180.025
positive regulation of mitotic metaphase anaphase transitionGO:0045842100.025
covalent chromatin modificationGO:00165691060.025
Mouse Rat
regionalizationGO:00030024160.025
intracellular transportGO:00469072280.025
regulation of protein kinase activityGO:0045859510.024
negative regulation of catabolic processGO:0009895360.024
positive regulation of growthGO:0045927750.024
Rat
protein import into nucleusGO:0006606510.024
dendrite developmentGO:00163582040.023
regulation of protein serine threonine kinase activityGO:0071900250.023
Yeast
stem cell divisionGO:0017145690.023
camera type eye developmentGO:004301040.023
kinetochore organizationGO:005138390.023
cellular response to chemical stimulusGO:00708871990.023
Rat
microtubule based movementGO:0007018510.023
negative regulation of developmental processGO:00510932010.023
negative regulation of proteolysis involved in cellular protein catabolic processGO:1903051170.023
rna interferenceGO:0016246270.022
immune system processGO:00023763470.021
Mouse
cellular protein complex assemblyGO:0043623710.021
embryonic pattern specificationGO:00098801740.021
membrane disassemblyGO:003039740.021
dna integrity checkpointGO:0031570810.020
transcription from rna polymerase ii promoterGO:00063663680.020
larval developmentGO:00021641040.020
Worm
lateral inhibitionGO:00463312060.020
positive regulation of phosphate metabolic processGO:00459371390.020
Rat Worm
spindle midzone assemblyGO:005125540.020
posttranscriptional gene silencingGO:0016441460.020
regulation of gene silencingGO:0060968630.019
cellular macromolecular complex assemblyGO:00346221530.019
centrosome duplicationGO:00512981210.019
mitotic sister chromatid cohesionGO:000706460.018
positive regulation of nucleic acid templated transcriptionGO:19035082660.018
intracellular signal transductionGO:00355563000.018
regulation of developmental growthGO:00486381740.018
Rat
male sex differentiationGO:0046661250.017
regulation of g1 s transition of mitotic cell cycleGO:2000045230.017
negative regulation of protein processingGO:0010955310.017
positive regulation of cellular component biogenesisGO:0044089800.016
positive regulation of cell divisionGO:0051781160.016
columnar cuboidal epithelial cell differentiationGO:00020652560.016
phagocytosisGO:00069092150.016
regulation of molecular functionGO:00650092170.016
single organism biosynthetic processGO:00447112060.016
Yeast
gland developmentGO:00487321910.015
Mouse
regulation of transcription from rna polymerase ii promoterGO:00063573780.015
intercellular bridge organizationGO:0043063140.015
reproductive behaviorGO:00190981220.015
brain developmentGO:00074201200.015
protein localization to nucleusGO:0034504550.015
nitrogen compound transportGO:0071705850.015
dna damage checkpointGO:0000077780.014
positive regulation of phosphorylationGO:0042327870.014
Rat Worm
negative regulation of gtp catabolic processGO:003312510.014
regulation of striated muscle contractionGO:000694220.014
cytoplasmic microtubule organizationGO:0031122220.014
response to temperature stimulusGO:00092661060.013
regulation of catalytic activityGO:00507901850.013
positive regulation of biosynthetic processGO:00098913160.013
Yeast
spindle assembly checkpointGO:0071173110.013
nuclear importGO:0051170510.013
negative regulation of chromosome organizationGO:2001251190.013
endomembrane system organizationGO:00102561190.013
negative regulation of nucleoside metabolic processGO:004597810.013
mitochondrial membrane organizationGO:000700630.013
rna transportGO:0050658460.013
response to light stimulusGO:00094161240.013
negative regulation of mitosisGO:0045839160.013
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178650.013
single organism nuclear importGO:1902593510.013
negative regulation of wnt signaling pathwayGO:0030178280.013
negative regulation of phosphorus metabolic processGO:0010563450.013
Yeast Rat
cellular protein localizationGO:00346131600.012
cell cycle checkpointGO:0000075950.012
Human
positive regulation of developmental processGO:00510941430.012
Rat
negative regulation of protein maturationGO:1903318310.012
regulation of postsynaptic membrane potentialGO:006007850.012
oocyte axis specificationGO:00073091080.012
dephosphorylationGO:0016311510.012
Yeast
g2 dna damage checkpointGO:0031572690.012
mitotic g2 dna damage checkpointGO:0007095690.012
nuclear dna replicationGO:003326010.012
establishment of spindle localizationGO:0051293220.012
regulation of dna replicationGO:0006275130.012
Yeast
establishment of rna localizationGO:0051236470.012
negative regulation of signal transductionGO:00099682060.011
regulation of cytoplasmic transportGO:1903649470.011
embryonic organ developmentGO:0048568500.011
regulation of exit from mitosisGO:000709670.011
regulation of protein maturationGO:1903317320.011
neural precursor cell proliferationGO:0061351750.011
lipid storageGO:0019915380.011
negative regulation of protein depolymerizationGO:1901880230.011
Human
negative regulation of gtpase activityGO:003426010.011
positive regulation of bindingGO:005109940.011
cellularizationGO:0007349900.011
retina development in camera type eyeGO:006004140.011
regulation of embryonic developmentGO:0045995680.011
negative regulation of cell cycle phase transitionGO:19019881030.011
Human
nucleobase containing compound transportGO:0015931560.011
eggshell formationGO:00307031050.011
negative regulation of nucleotide metabolic processGO:004598040.010
digestive tract morphogenesisGO:00485461270.010
positive regulation of dna metabolic processGO:0051054120.010
Yeast
camera type eye morphogenesisGO:004859320.010
sensory organ morphogenesisGO:00905962600.010
oocyte dorsal ventral axis specificationGO:0007310340.010
dorsal ventral pattern formationGO:00099531330.010
regulation of phosphate metabolic processGO:00192202100.010
endomitotic cell cycleGO:000711370.010
stem cell differentiationGO:00488631170.010
regulation of protein processingGO:0070613320.010

CycB disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
cancerDOID:16200.087
organ system cancerDOID:005068600.087
disease of cellular proliferationDOID:1456600.087
disease of anatomical entityDOID:700.036