Drosophila melanogaster

132 known processes

Dll (Dmel_CG3629)

Distal-less

(Aliases: E(Arp),dl,Art,Ba,En(Arp),l(2)01092,dll,CG3629,BcDNA:LP01770,Dmel\CG3629,2.7,l(2)387)

Dll biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of transcription from rna polymerase ii promoterGO:00063573780.996
Mouse
leg disc developmentGO:0035218920.993
imaginal disc derived appendage morphogenesisGO:00351143950.986
positive regulation of macromolecule metabolic processGO:00106044050.971
imaginal disc derived leg segmentationGO:0036011260.969
post embryonic appendage morphogenesisGO:00351203850.967
regionalizationGO:00030024160.964
appendage morphogenesisGO:00351073970.959
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.949
imaginal disc derived leg morphogenesisGO:0007480800.937
positive regulation of rna metabolic processGO:00512542710.923
camera type eye developmentGO:004301040.922
Zebrafish
positive regulation of nucleobase containing compound metabolic processGO:00459353320.908
anterior posterior pattern specificationGO:00099521360.904
positive regulation of rna biosynthetic processGO:19026802660.889
appendage developmentGO:00487364010.836
imaginal disc derived appendage developmentGO:00487373990.833
positive regulation of transcription dna templatedGO:00458932660.830
regulation of cell fate commitmentGO:0010453290.828
positive regulation of nitrogen compound metabolic processGO:00511733540.827
leg disc morphogenesisGO:0007478800.816
tissue morphogenesisGO:00487292970.808
Zebrafish
heart developmentGO:0007507820.775
positive regulation of nucleic acid templated transcriptionGO:19035082660.741
circulatory system developmentGO:0072359820.733
eye antennal disc developmentGO:0035214600.726
regulation of cell fate specificationGO:0042659270.660
imaginal disc derived wing morphogenesisGO:00074763370.647
renal tubule developmentGO:0061326640.612
positive regulation of macromolecule biosynthetic processGO:00105572830.603
negative regulation of nucleobase containing compound metabolic processGO:00459342610.593
Mouse
positive regulation of gene expressionGO:00106282900.586
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.560
Mouse
sensory organ morphogenesisGO:00905962600.560
Zebrafish Mouse
epithelial cell developmentGO:00020642740.551
epithelial cell differentiationGO:00308553220.548
Zebrafish Mouse
camera type eye photoreceptor cell differentiationGO:006021920.540
neuron fate specificationGO:0048665120.539
Zebrafish
dendrite guidanceGO:0070983210.533
regulation of nervous system developmentGO:00519602480.512
Mouse
retina development in camera type eyeGO:006004140.511
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.509
Mouse
eye developmentGO:00016543230.485
Zebrafish
renal system developmentGO:0072001720.480
wing disc pattern formationGO:0035222660.477
wing disc morphogenesisGO:00074723440.471
embryonic organ developmentGO:0048568500.448
Zebrafish Mouse
imaginal disc pattern formationGO:0007447910.446
cell fate specificationGO:0001708710.441
Zebrafish
segmentationGO:00352822070.421
localization of cellGO:00516742570.416
cardiovascular system developmentGO:0072358820.407
blastoderm segmentationGO:00073501590.399
muscle structure developmentGO:00610612240.396
appendage segmentationGO:0035285260.389
hair cell differentiationGO:0035315470.379
Zebrafish
male courtship behaviorGO:0008049630.350
retinal cone cell differentiationGO:004267020.343
gland developmentGO:00487321910.335
regulation of r7 cell differentiationGO:0045676150.328
embryonic pattern specificationGO:00098801740.317
tube developmentGO:00352952440.316
positive regulation of biosynthetic processGO:00098913160.299
negative regulation of macromolecule biosynthetic processGO:00105582700.297
Mouse
heart morphogenesisGO:0003007320.295
eye morphogenesisGO:00485922600.295
eye photoreceptor cell differentiationGO:00017541450.285
regulation of photoreceptor cell differentiationGO:0046532340.267
negative regulation of rna metabolic processGO:00512532510.262
Mouse
brain developmentGO:00074201200.261
regulation of cell differentiationGO:00455953020.258
Mouse
smoothened signaling pathwayGO:0007224490.244
head developmentGO:00603221350.234
kidney morphogenesisGO:006099330.232
neurological system processGO:00508773580.230
neuroblast differentiationGO:0014016290.228
compound eye developmentGO:00487493070.224
segment specificationGO:0007379330.222
compound eye morphogenesisGO:00017452490.222
limb developmentGO:006017310.220
Mouse
head segmentationGO:0035287130.220
malpighian tubule developmentGO:0072002640.215
hindgut morphogenesisGO:0007442580.209
columnar cuboidal epithelial cell differentiationGO:00020652560.204
specification of segmental identity trunkGO:003529270.199
neural retina developmentGO:000340740.189
compound eye photoreceptor cell differentiationGO:00017511400.189
sex differentiationGO:0007548810.186
transcription from rna polymerase ii promoterGO:00063663680.181
Mouse
specification of organ identityGO:001009230.180
negative regulation of biosynthetic processGO:00098902770.178
Mouse
negative regulation of cellular biosynthetic processGO:00313272770.176
Mouse
nephron tubule morphogenesisGO:007207830.174
protein dna complex assemblyGO:0065004630.171
epithelial cell proliferationGO:0050673150.171
Mouse
determination of imaginal disc primordiumGO:0007445110.167
positive regulation of cellular biosynthetic processGO:00313283160.163
negative regulation of response to stimulusGO:00485852580.162
Mouse
negative regulation of transcription dna templatedGO:00458922370.162
Mouse
reproductive behaviorGO:00190981220.161
adult behaviorGO:00305341370.161
reproductive structure developmentGO:0048608740.160
photoreceptor cell differentiationGO:00465301700.160
renal tubule morphogenesisGO:0061333440.157
negative regulation of nitrogen compound metabolic processGO:00511722650.156
Mouse
chaeta developmentGO:0022416970.155
stem cell differentiationGO:00488631170.149
retina morphogenesis in camera type eyeGO:006004220.143
antennal developmentGO:0007469250.140
larval developmentGO:00021641040.139
Worm
morphogenesis of an epitheliumGO:00020092760.139
Zebrafish
urogenital system developmentGO:0001655720.137
response to toxic substanceGO:0009636220.134
body morphogenesisGO:001017120.134
dendrite morphogenesisGO:00488131990.132
sensory perceptionGO:00076001960.131
limb morphogenesisGO:003510810.124
Mouse
secretionGO:00469031090.122
cell deathGO:00082192790.121
Mouse
mesodermal cell fate specificationGO:000750120.118
zygotic determination of anterior posterior axis embryoGO:0007354270.116
specification of segmental identity headGO:0007380110.112
chaeta morphogenesisGO:0008407420.111
digestive tract developmentGO:00485651490.110
protein dna complex subunit organizationGO:0071824860.110
regulation of organ morphogenesisGO:2000027780.110
camera type eye morphogenesisGO:004859320.109
morphogenesis of a branching epitheliumGO:0061138450.107
ectodermal placode morphogenesisGO:007169740.106
Zebrafish
negative regulation of rna biosynthetic processGO:19026792400.105
Mouse
chemotaxisGO:00069352490.104
reproductive system developmentGO:0061458740.103
antennal morphogenesisGO:0048800140.102
leg disc proximal distal pattern formationGO:000747990.101
dorsal ventral pattern formationGO:00099531330.100
somatic muscle developmentGO:0007525660.099
vesicle mediated transportGO:00161923810.098
response to organic cyclic compoundGO:0014070890.098
central nervous system developmentGO:00074172010.098
embryo development ending in birth or egg hatchingGO:00097921520.097
Mouse Worm
positive regulation of signalingGO:00230562430.096
negative regulation of nucleic acid templated transcriptionGO:19035072400.095
Mouse
embryonic development via the syncytial blastodermGO:00017001480.094
axis specificationGO:00097981670.094
growthGO:00400073590.094
imaginal disc derived leg joint morphogenesisGO:0016348150.093
eye antennal disc morphogenesisGO:0007455340.092
neuron fate commitmentGO:0048663500.092
Zebrafish Mouse
imaginal disc derived wing margin morphogenesisGO:0008587410.090
spinal cord developmentGO:002151010.088
apoptotic process involved in morphogenesisGO:006056130.088
male courtship behavior veined wing extensionGO:0048065220.087
stem cell proliferationGO:0072089880.087
muscle tissue developmentGO:0060537300.086
negative regulation of notch signaling pathwayGO:0045746410.085
Mouse
anterior posterior axis specificationGO:00099481090.084
columnar cuboidal epithelial cell developmentGO:00020662490.084
malpighian tubule morphogenesisGO:0007443440.084
anterior malpighian tubule developmentGO:0061327120.084
cell migrationGO:00164772380.082
kidney epithelium developmentGO:007207330.081
cardiocyte differentiationGO:0035051290.080
imaginal disc derived wing vein specificationGO:0007474480.079
dendrite developmentGO:00163582040.079
regulation of cell developmentGO:00602842150.078
Mouse
kidney developmentGO:000182230.078
multi organism behaviorGO:00517051750.077
response to abiotic stimulusGO:00096283410.077
regulation of epithelial cell differentiationGO:003085640.076
positive regulation of response to stimulusGO:00485843230.075
lymph gland developmentGO:0048542280.075
cell proliferationGO:00082832990.074
Mouse
regulation of epithelial cell proliferationGO:005067840.071
Mouse
hindgut developmentGO:0061525580.071
courtship behaviorGO:0007619680.070
ovarian follicle cell developmentGO:00307072480.068
nephron developmentGO:007200630.068
muscle cell fate commitmentGO:0042693140.067
cell fate commitment involved in pattern specificationGO:0060581310.066
dorsal ventral pattern formation imaginal discGO:0007450510.066
anterior posterior axis specification embryoGO:00085951030.065
embryonic morphogenesisGO:00485982060.065
Zebrafish Mouse
connective tissue developmentGO:006144830.064
Zebrafish
digestive tract morphogenesisGO:00485461270.063
terminal region determinationGO:0007362250.063
positive regulation of signal transductionGO:00099672230.059
trunk segmentationGO:003529080.059
forebrain developmentGO:003090020.058
Mouse
organ growthGO:0035265560.058
ocellus developmentGO:000805640.058
anterior head developmentGO:009706530.057
equator specificationGO:004531740.057
single organism intracellular transportGO:19025822070.056
outflow tract morphogenesisGO:000315140.056
nephron epithelium morphogenesisGO:007208830.056
photoreceptor cell fate specificationGO:004370490.055
establishment of localization in cellGO:00516494020.055
protein transportGO:00150311550.055
regulation of notch signaling pathwayGO:00085931000.054
Mouse
endocytosisGO:00068973100.054
regulation of neuron differentiationGO:00456641030.053
cardioblast differentiationGO:0010002200.053
torso signaling pathwayGO:0008293210.051
detection of stimulus involved in sensory perceptionGO:0050906920.051
neural precursor cell proliferationGO:0061351750.051
regulation of organ growthGO:0046620420.049
cell motilityGO:00488702510.049
response to organic substanceGO:00100332840.049
cardiac cell fate commitmentGO:0060911170.048
tissue deathGO:00162711020.048
positive regulation of cell communicationGO:00106472500.048
multicellular organismal reproductive behaviorGO:00330571100.048
hindbrain developmentGO:003090220.047
regulation of imaginal disc derived wing sizeGO:0044719200.046
embryonic axis specificationGO:00005781070.046
muscle cell fate specificationGO:004269470.045
establishment of protein localizationGO:00451841630.045
regulation of defense responseGO:00313471020.043
negative regulation of signal transductionGO:00099682060.043
Mouse
notum cell fate specificationGO:003531050.042
axon guidanceGO:00074112330.040
regulation of cell proliferationGO:00421271630.040
Mouse
developmental maturationGO:00217001720.040
negative regulation of gene expressionGO:00106293870.040
neuroblast developmentGO:0014019130.039
positive regulation of developmental processGO:00510941430.039
neuron recognitionGO:00080381010.038
antennal joint developmentGO:004809850.037
female genitalia developmentGO:003054060.037
neuroblast fate commitmentGO:0014017190.037
photoreceptor cell fate commitmentGO:0046552410.037
nephron epithelium developmentGO:007200930.037
nephron morphogenesisGO:007202830.036
response to nitrogen compoundGO:1901698900.035
cardioblast cell fate commitmentGO:0042684140.034
male courtship behavior veined wing vibrationGO:0016545210.034
cellular protein modification processGO:00064644380.034
histolysisGO:00075591020.033
telencephalon developmentGO:002153720.033
Mouse
mesenchymal cell differentiationGO:004876210.033
positive regulation of cellular protein metabolic processGO:00322701180.033
nitrogen compound transportGO:0071705850.032
gland morphogenesisGO:00226121450.032
tube morphogenesisGO:00352391910.032
hematopoietic or lymphoid organ developmentGO:0048534570.032
multi organism reproductive behaviorGO:00447051210.032
protein modification processGO:00362114380.032
muscle organ developmentGO:00075171270.031
response to woundingGO:0009611940.031
epidermis developmentGO:0008544650.031
Zebrafish
organic substance transportGO:00717022570.031
negative regulation of signalingGO:00230572190.031
Mouse
striated muscle tissue developmentGO:0014706270.030
cell divisionGO:00513012480.030
single organism behaviorGO:00447083910.030
response to endogenous stimulusGO:00097191190.029
epithelial tube morphogenesisGO:0060562880.028
taxisGO:00423303040.027
nephron tubule developmentGO:007208030.027
response to lipidGO:0033993380.027
digestive system developmentGO:00551231490.027
phagocytosisGO:00069092150.027
branching morphogenesis of an epithelial tubeGO:0048754450.027
r7 cell differentiationGO:0045466430.027
wing disc dorsal ventral pattern formationGO:0048190470.027
adult locomotory behaviorGO:0008344760.026
tripartite regional subdivisionGO:00073511030.026
female sex differentiationGO:0046660200.026
embryonic hindgut morphogenesisGO:0048619480.026
chorion containing eggshell formationGO:00073041050.025
axonogenesisGO:00074092900.025
eye photoreceptor cell developmentGO:0042462810.024
immune system developmentGO:0002520570.024
developmental growthGO:00485892800.024
sensory perception of mechanical stimulusGO:0050954720.024
negative regulation of nervous system developmentGO:0051961920.024
Mouse
regulation of catalytic activityGO:00507901850.024
positive regulation of protein metabolic processGO:00512471280.024
neuron projection guidanceGO:00974852410.023
organ formationGO:0048645390.023
macromolecule catabolic processGO:00090571610.023
regulation of heart morphogenesisGO:200082630.023
mesoderm developmentGO:0007498780.023
mesenchymal cell developmentGO:001403110.023
positive regulation of cell differentiationGO:0045597640.022
matingGO:00076181200.022
synapse assemblyGO:00074161430.022
notch signaling pathwayGO:00072191200.022
Mouse
phosphorylationGO:00163102940.022
multicellular organismal agingGO:00102591400.022
muscle tissue morphogenesisGO:006041520.022
dna templated transcriptional preinitiation complex assemblyGO:0070897200.021
developmental growth involved in morphogenesisGO:0060560650.021
protein localizationGO:00081042840.021
stem cell developmentGO:0048864790.021
cell fate determinationGO:0001709910.021
mesenchyme developmentGO:006048590.021
eye photoreceptor cell fate commitmentGO:0042706370.021
immune system processGO:00023763470.021
skeletal muscle organ developmentGO:0060538480.021
negative regulation of cellular metabolic processGO:00313243820.021
Mouse
regulation of neural precursor cell proliferationGO:2000177350.020
developmental inductionGO:003112830.020
central nervous system neuron differentiationGO:002195380.020
Mouse
regulation of neurogenesisGO:00507671580.020
Mouse
mating behaviorGO:00076171060.020
regulation of transportGO:00510491810.019
cell fate specification involved in pattern specificationGO:006057380.019
posterior head segmentationGO:003528960.019
wound healingGO:0042060750.019
regulation of dendrite morphogenesisGO:0048814280.019
regulation of molecular functionGO:00650092170.019
negative regulation of multicellular organismal processGO:00512411420.019
Mouse
gonad developmentGO:0008406500.018
secretion by cellGO:00329401010.018
positive regulation of cell deathGO:0010942690.018
glial cell differentiationGO:0010001350.018
Mouse
muscle organ morphogenesisGO:004864470.018
catabolic processGO:00090564090.018
nerve developmentGO:002167560.018
wing and notum subfield formationGO:0035309130.018
organic substance catabolic processGO:19015753080.018
peripheral nervous system developmentGO:0007422520.018
mesoderm morphogenesisGO:0048332220.017
development of primary sexual characteristicsGO:0045137500.017
positive regulation of notch signaling pathwayGO:0045747340.017
skin developmentGO:0043588650.017
Zebrafish
negative regulation of cell proliferationGO:0008285690.017
exocrine system developmentGO:00352721620.017
negative regulation of epithelial cell proliferationGO:005068040.017
circadian regulation of gene expressionGO:003292250.017
ecdysone mediated induction of salivary gland cell autophagic cell deathGO:0035072120.016
regulation of localizationGO:00328792750.016
imaginal disc derived wing vein morphogenesisGO:0008586440.016
cell cell signaling involved in cell fate commitmentGO:00451682100.016
glandular epithelial cell differentiationGO:000206710.016
muscle cell differentiationGO:00426921030.016
programmed cell deathGO:00125012570.016
Mouse
positive regulation of multicellular organismal processGO:00512401430.016
morphogenesis of a polarized epitheliumGO:0001738930.016
cellular response to chemical stimulusGO:00708871990.016
regulation of cellular localizationGO:00603411360.016
enteroendocrine cell differentiationGO:003588310.015
regulation of programmed cell deathGO:00430671520.015
Mouse
asymmetric cell divisionGO:0008356370.015
regulation of hormone levelsGO:0010817400.015
instar larval developmentGO:0002168550.015
negative regulation of cell fate specificationGO:0009996150.015
regulation of reproductive processGO:2000241540.015
enzyme linked receptor protein signaling pathwayGO:00071671790.015
positive regulation of cellular amide metabolic processGO:0034250260.015
genital disc sexually dimorphic developmentGO:003526340.015
genitalia developmentGO:0048806260.015
ameboidal type cell migrationGO:00016671510.014
positive regulation of phosphorylationGO:0042327870.014
agingGO:00075681430.014
negative regulation of cell communicationGO:00106482230.014
Mouse
negative regulation of sequence specific dna binding transcription factor activityGO:004343340.014
establishment of planar polarityGO:0001736870.014
positive regulation of intracellular protein transportGO:0090316300.014
multi multicellular organism processGO:00447061230.014
positive regulation of cell proliferationGO:0008284470.014
Mouse
genital disc developmentGO:0035215440.014
positive regulation of phosphorus metabolic processGO:00105621390.014
haltere developmentGO:0007482100.014
response to organonitrogen compoundGO:0010243750.014
regulation of cell morphogenesis involved in differentiationGO:0010769610.014
response to oxygen containing compoundGO:19017002000.014
endoderm formationGO:000170630.014
deathGO:00162652840.014
Mouse
intracellular transportGO:00469072280.014
response to ecdysoneGO:0035075340.014
gonad morphogenesisGO:003526270.014
cellular response to hexose stimulusGO:007133110.013
eggshell formationGO:00307031050.013
cell maturationGO:00484691440.013
cellular catabolic processGO:00442483720.013
signal releaseGO:0023061490.013
proximal distal pattern formationGO:0009954150.013
germ cell migrationGO:0008354430.013
defense responseGO:00069523000.013
cellular response to monosaccharide stimulusGO:007132620.013
embryonic hemopoiesisGO:0035162260.013
male gamete generationGO:00482322010.013
positive regulation of nervous system developmentGO:0051962690.013
cell activationGO:000177590.013
regulation of neuron projection developmentGO:0010975690.013
regulation of phosphatase activityGO:001092130.013
negative regulation of programmed cell deathGO:0043069720.013
Mouse
autophagyGO:00069141080.012
rhythmic behaviorGO:0007622760.012
protein modification by small protein conjugationGO:0032446790.012
single organism cellular localizationGO:19025801800.012
transcription initiation from rna polymerase ii promoterGO:0006367250.012
positive regulation of neurogenesisGO:0050769410.012
regulation of system processGO:0044057360.012
sensory neuron axon guidanceGO:009737420.012
developmental programmed cell deathGO:00106231380.012
apposition of dorsal and ventral imaginal disc derived wing surfacesGO:0007475150.012
intracellular receptor signaling pathwayGO:0030522190.012
regulation of stem cell proliferationGO:0072091400.012
tissue migrationGO:00901301550.012
regulation of hydrolase activityGO:0051336970.012
cranial nerve developmentGO:002154510.012
rna polymerase ii transcriptional preinitiation complex assemblyGO:0051123200.012
positive regulation of epithelial cell differentiationGO:003085810.012
regulation of cell cycleGO:00517262910.012
leg disc pattern formationGO:0035223110.012
open tracheal system developmentGO:00074242040.011
compound eye photoreceptor developmentGO:0042051780.011
regulation of rna polymerase ii transcriptional preinitiation complex assemblyGO:004589810.011
mesodermal cell fate commitmentGO:000171070.011
response to biotic stimulusGO:00096072940.011
photoreceptor cell developmentGO:0042461960.011
hemocyte differentiationGO:0042386380.011
protein importGO:0017038550.011
ectodermal placode developmentGO:007169640.011
Zebrafish
cellular response to organic substanceGO:00713101320.011
embryonic heart tube developmentGO:0035050220.011
non sensory hair organizationGO:0035316470.011
respiratory system developmentGO:00605412130.011
cardiac muscle cell differentiationGO:005500740.011
positive regulation of proteolysisGO:0045862520.011
positive regulation of transportGO:0051050920.011
response to alcoholGO:0097305950.011
apoptotic processGO:00069151590.010
Mouse
myotube cell developmentGO:001490430.010
dorsal ventral axis specificationGO:0009950660.010
establishment of tissue polarityGO:0007164870.010
regulation of phosphate metabolic processGO:00192202100.010
negative regulation of cell fate commitmentGO:0010454170.010
development of primary female sexual characteristicsGO:0046545120.010
musculoskeletal movementGO:005088130.010

Dll disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.042
disease of cellular proliferationDOID:1456600.024
organ system cancerDOID:005068600.024
cancerDOID:16200.024
cardiovascular system diseaseDOID:128700.013