IMP: Integrative Multi-species Prediction

Drosophila melanogaster

24 known processes

wapl (Dmel_CG3707)

wings apart-like

(Aliases: l(1)N2,Dmel\CG3707,EG:87B1.2,wap,l(1)N5[72],pasc,l74,l(1)2Df,RNA D,C204,l(1)C204,N2,RNAD,CG3707,l(1)2Dd)

FLYBASE: FBgn0004655
Entrez: 31187
UniProtKB: Q9W517
UniProtKB: X2JAA8

Process Predictions
Disease Predictions

wapl biological process predictions

Show only novel predictionsHighlight processes of functional analogs

Filter by process size:

Biological process	GO term ID	Process size	Probability	Func Analog Org
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.933	Human
meiotic chromosome segregation	GO:0045132	59	0.911
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.911
meiotic cell cycle	GO:0051321	171	0.883
nuclear division	GO:0000280	332	0.845
negative regulation of cellular metabolic process	GO:0031324	382	0.833	Human
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.833	Human
negative regulation of gene expression epigenetic	GO:0045814	77	0.826
gene silencing	GO:0016458	138	0.824
meiotic nuclear division	GO:0007126	151	0.803
regulation of chromatin silencing	GO:0031935	36	0.787
negative regulation of rna biosynthetic process	GO:1902679	240	0.779
response to other organism	GO:0051707	293	0.758
regulation of chromosome organization	GO:0033044	64	0.690	Human
negative regulation of gene expression	GO:0010629	387	0.665
tube development	GO:0035295	244	0.664
meiotic cell cycle process	GO:1903046	132	0.658
regulation of cell cycle	GO:0051726	291	0.637	Human
spindle organization	GO:0007051	253	0.624
chromosome organization	GO:0051276	360	0.615
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.602	Human
dendrite morphogenesis	GO:0048813	199	0.573
negative regulation of rna metabolic process	GO:0051253	251	0.555
positive regulation of transcription dna templated	GO:0045893	266	0.551
covalent chromatin modification	GO:0016569	106	0.499
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.490
chromatin modification	GO:0016568	147	0.452
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.449
reproductive structure development	GO:0048608	74	0.447
central nervous system development	GO:0007417	201	0.436
regulation of organelle organization	GO:0033043	196	0.425	Human
positive regulation of cellular component organization	GO:0051130	156	0.414
histone acetylation	GO:0016573	38	0.408
histone modification	GO:0016570	106	0.394
morphogenesis of an epithelium	GO:0002009	276	0.384
regulation of cellular protein metabolic process	GO:0032268	243	0.378
embryo development ending in birth or egg hatching	GO:0009792	152	0.364	Worm
muscle structure development	GO:0061061	224	0.361
tissue morphogenesis	GO:0048729	297	0.348
establishment of localization in cell	GO:0051649	402	0.333
cellular response to dna damage stimulus	GO:0006974	223	0.321
negative regulation of mitotic cell cycle phase transition	GO:1901991	103	0.314
organelle assembly	GO:0070925	198	0.312
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.311
mating	GO:0007618	120	0.309
mitotic cell cycle checkpoint	GO:0007093	88	0.297
purine nucleotide catabolic process	GO:0006195	109	0.294
regulation of protein metabolic process	GO:0051246	256	0.293
dna metabolic process	GO:0006259	227	0.278	Human
multi organism behavior	GO:0051705	175	0.270	Worm
ribonucleotide metabolic process	GO:0009259	145	0.267
multicellular organismal reproductive behavior	GO:0033057	110	0.265	Worm
mitotic dna damage checkpoint	GO:0044773	74	0.265
peptidyl lysine modification	GO:0018205	57	0.259
imaginal disc derived appendage development	GO:0048737	399	0.258
positive regulation of cellular biosynthetic process	GO:0031328	316	0.252
dendrite development	GO:0016358	204	0.244
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.241	Human
protein modification by small protein conjugation or removal	GO:0070647	106	0.239
chromatin silencing	GO:0006342	76	0.230
sensory organ morphogenesis	GO:0090596	260	0.228
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.219
organelle fission	GO:0048285	340	0.219
embryonic morphogenesis	GO:0048598	206	0.218
protein acetylation	GO:0006473	39	0.209
response to external biotic stimulus	GO:0043207	293	0.201
epithelial cell differentiation	GO:0030855	322	0.201
cell migration	GO:0016477	238	0.198
positive regulation of rna biosynthetic process	GO:1902680	266	0.196
sex differentiation	GO:0007548	81	0.191
negative regulation of cellular component organization	GO:0051129	108	0.190	Human
chromatin organization	GO:0006325	207	0.187
positive regulation of organelle organization	GO:0010638	65	0.183
compound eye photoreceptor cell differentiation	GO:0001751	140	0.183
cellular protein modification process	GO:0006464	438	0.182
dna damage checkpoint	GO:0000077	78	0.182
regulation of gene expression epigenetic	GO:0040029	128	0.178
internal protein amino acid acetylation	GO:0006475	38	0.178
nucleoside triphosphate metabolic process	GO:0009141	120	0.172
regulation of molecular function	GO:0065009	217	0.168	Human
purine ribonucleotide catabolic process	GO:0009154	109	0.167
protein complex assembly	GO:0006461	200	0.165
negative regulation of cellular biosynthetic process	GO:0031327	277	0.164	Human
regulation of catalytic activity	GO:0050790	185	0.156
response to biotic stimulus	GO:0009607	294	0.152
nucleotide catabolic process	GO:0009166	109	0.149
regulation of cell cycle phase transition	GO:1901987	130	0.149
epithelial cell development	GO:0002064	274	0.147
chromosome segregation	GO:0007059	157	0.147
purine nucleotide metabolic process	GO:0006163	146	0.143
columnar cuboidal epithelial cell development	GO:0002066	249	0.142
organonitrogen compound metabolic process	GO:1901564	318	0.142
regulation of immune system process	GO:0002682	176	0.138
peptidyl lysine acetylation	GO:0018394	39	0.137
localization of cell	GO:0051674	257	0.135
establishment or maintenance of cell polarity	GO:0007163	167	0.132
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.132
macromolecular complex assembly	GO:0065003	256	0.132
positive regulation of gene expression	GO:0010628	290	0.131
immune system process	GO:0002376	347	0.130
neuron projection guidance	GO:0097485	241	0.129
internal peptidyl lysine acetylation	GO:0018393	38	0.128
transcription from rna polymerase ii promoter	GO:0006366	368	0.124
cell division	GO:0051301	248	0.121
compound eye photoreceptor development	GO:0042051	78	0.117
ribonucleoside triphosphate catabolic process	GO:0009203	108	0.117
negative regulation of cell cycle process	GO:0010948	109	0.117	Human
dna integrity checkpoint	GO:0031570	81	0.117
negative regulation of response to stimulus	GO:0048585	258	0.115
heterocycle catabolic process	GO:0046700	166	0.114
immune response	GO:0006955	246	0.112
regulation of anatomical structure morphogenesis	GO:0022603	242	0.111
establishment of protein localization	GO:0045184	163	0.111
protein transport	GO:0015031	155	0.109
regulation of gene silencing	GO:0060968	63	0.109
negative regulation of transcription dna templated	GO:0045892	237	0.108
cellular catabolic process	GO:0044248	372	0.107
purine ribonucleoside monophosphate metabolic process	GO:0009167	50	0.103
mitotic spindle organization	GO:0007052	220	0.102
leg disc development	GO:0035218	92	0.102
nucleotide metabolic process	GO:0009117	161	0.102
negative regulation of biosynthetic process	GO:0009890	277	0.101	Human
eye photoreceptor cell development	GO:0042462	81	0.100
purine ribonucleoside metabolic process	GO:0046128	127	0.098
ribonucleoside triphosphate metabolic process	GO:0009199	119	0.098
female meiosis chromosome segregation	GO:0016321	33	0.098
negative regulation of cell cycle phase transition	GO:1901988	103	0.096
blastoderm segmentation	GO:0007350	159	0.095
defense response	GO:0006952	300	0.094
regulation of protein modification process	GO:0031399	112	0.092
cell motility	GO:0048870	251	0.091
imaginal disc derived wing morphogenesis	GO:0007476	337	0.090
regulation of cellular amino acid metabolic process	GO:0006521	0	0.089
columnar cuboidal epithelial cell differentiation	GO:0002065	256	0.087
protein modification process	GO:0036211	438	0.086
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.085
single organism catabolic process	GO:0044712	228	0.084
regulation of phosphorus metabolic process	GO:0051174	210	0.083
purine containing compound metabolic process	GO:0072521	155	0.081
regulation of immune response	GO:0050776	118	0.081
positive regulation of biosynthetic process	GO:0009891	316	0.078
defense response to other organism	GO:0098542	225	0.078
multi multicellular organism process	GO:0044706	123	0.078	Worm
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.077
purine nucleoside metabolic process	GO:0042278	127	0.077
carbohydrate derivative metabolic process	GO:1901135	217	0.077
establishment of planar polarity	GO:0001736	87	0.077
regulation of hydrolase activity	GO:0051336	97	0.076
cell fate specification	GO:0001708	71	0.073
protein maturation	GO:0051604	71	0.072
positive regulation of hydrolase activity	GO:0051345	78	0.069
regulation of cellular ketone metabolic process	GO:0010565	3	0.068
regulation of cellular amine metabolic process	GO:0033238	3	0.068
male mating behavior	GO:0060179	70	0.067
cell cycle checkpoint	GO:0000075	95	0.067
purine ribonucleotide metabolic process	GO:0009150	145	0.067
axon development	GO:0061564	297	0.067
single organism cellular localization	GO:1902580	180	0.064	Human
regulation of chromatin modification	GO:1903308	28	0.064
dna repair	GO:0006281	54	0.063
anterior posterior pattern specification	GO:0009952	136	0.062
embryonic pattern specification	GO:0009880	174	0.062
positive regulation of chromatin silencing	GO:0031937	16	0.061
chorion containing eggshell formation	GO:0007304	105	0.060
organophosphate metabolic process	GO:0019637	195	0.059
regulation of cell proliferation	GO:0042127	163	0.059
eye morphogenesis	GO:0048592	260	0.058
female meiotic division	GO:0007143	70	0.058
larval development	GO:0002164	104	0.058
positive regulation of macromolecule metabolic process	GO:0010604	405	0.057
regulation of cell shape	GO:0008360	113	0.057
head development	GO:0060322	135	0.057
intracellular transport	GO:0046907	228	0.057
purine ribonucleoside triphosphate catabolic process	GO:0009207	108	0.056
small molecule metabolic process	GO:0044281	305	0.055
purine nucleoside triphosphate metabolic process	GO:0009144	119	0.054
brain development	GO:0007420	120	0.053
response to alcohol	GO:0097305	95	0.053
eye photoreceptor cell differentiation	GO:0001754	145	0.052
positive regulation of molecular function	GO:0044093	136	0.052
histone h3 k9 acetylation	GO:0043970	3	0.052
macromolecule catabolic process	GO:0009057	161	0.051
amine metabolic process	GO:0009308	12	0.051
aromatic compound catabolic process	GO:0019439	166	0.050
neurological system process	GO:0050877	358	0.050
protein localization	GO:0008104	284	0.050	Human
body morphogenesis	GO:0010171	2	0.050
compound eye morphogenesis	GO:0001745	249	0.050
digestive system development	GO:0055123	149	0.049
chromatin remodeling	GO:0006338	72	0.049
cuticle development	GO:0042335	86	0.048
defense response to bacterium	GO:0042742	178	0.048
cellular ketone metabolic process	GO:0042180	24	0.048
regulation of proteolysis	GO:0030162	87	0.048
death	GO:0016265	284	0.048
negative regulation of signal transduction	GO:0009968	206	0.048
regulation of organ morphogenesis	GO:2000027	78	0.048
positive regulation of mitotic cell cycle	GO:0045931	34	0.047
regulation of cell death	GO:0010941	173	0.047
protein modification by small protein removal	GO:0070646	28	0.047
purine nucleoside catabolic process	GO:0006152	112	0.047
ribonucleoside metabolic process	GO:0009119	127	0.046
morphogenesis of a polarized epithelium	GO:0001738	93	0.046
cellular macromolecule localization	GO:0070727	220	0.045	Human
mitotic g2 dna damage checkpoint	GO:0007095	69	0.045
glycosyl compound catabolic process	GO:1901658	112	0.044
protein deacetylation	GO:0006476	9	0.044
photoreceptor cell differentiation	GO:0046530	170	0.043
negative regulation of organelle organization	GO:0010639	56	0.043	Human
actin cytoskeleton organization	GO:0030036	206	0.043
eye development	GO:0001654	323	0.043
meiosis i	GO:0007127	59	0.043
protein complex biogenesis	GO:0070271	201	0.042
positive regulation of catalytic activity	GO:0043085	118	0.042
cell cycle phase transition	GO:0044770	140	0.042
appendage development	GO:0048736	401	0.042
purine ribonucleoside triphosphate metabolic process	GO:0009205	119	0.042
negative regulation of cellular protein metabolic process	GO:0032269	85	0.041
development of primary sexual characteristics	GO:0045137	50	0.041
nucleoside catabolic process	GO:0009164	112	0.041
protein acylation	GO:0043543	42	0.041
regionalization	GO:0003002	416	0.041
regulation of meiosis	GO:0040020	3	0.040
chromatin mediated maintenance of transcription	GO:0048096	7	0.040
regulation of small gtpase mediated signal transduction	GO:0051056	93	0.040
reproductive system development	GO:0061458	74	0.040
negative regulation of cell communication	GO:0010648	223	0.039
purine nucleoside triphosphate catabolic process	GO:0009146	108	0.039
dna methylation	GO:0006306	4	0.039
positive regulation of nucleotide metabolic process	GO:0045981	55	0.039
embryonic development via the syncytial blastoderm	GO:0001700	148	0.038
ras protein signal transduction	GO:0007265	88	0.037
vesicle mediated transport	GO:0016192	381	0.037
organic substance transport	GO:0071702	257	0.037
glycosyl compound metabolic process	GO:1901657	127	0.037
nucleoside metabolic process	GO:0009116	127	0.037
nucleoside phosphate metabolic process	GO:0006753	162	0.037
positive regulation of cellular protein metabolic process	GO:0032270	118	0.036
axon guidance	GO:0007411	233	0.036
neuron recognition	GO:0008038	101	0.036
positive regulation of transferase activity	GO:0051347	26	0.036
single organism intracellular transport	GO:1902582	207	0.035
regulation of mitotic cell cycle phase transition	GO:1901990	130	0.035
gonad development	GO:0008406	50	0.035
negative regulation of cell cycle	GO:0045786	116	0.035	Human
cellular protein localization	GO:0034613	160	0.034	Human
compound eye development	GO:0048749	307	0.034
gtp metabolic process	GO:0046039	72	0.034
antimicrobial humoral response	GO:0019730	99	0.034
response to ecdysone	GO:0035075	34	0.033
purine ribonucleoside catabolic process	GO:0046130	112	0.033
small gtpase mediated signal transduction	GO:0007264	88	0.033
positive regulation of response to stimulus	GO:0048584	323	0.033
regulation of phosphate metabolic process	GO:0019220	210	0.033
meiotic chromosome condensation	GO:0010032	3	0.033
regulation of cell development	GO:0060284	215	0.032
limb development	GO:0060173	1	0.032
endocytosis	GO:0006897	310	0.032
protein dna complex subunit organization	GO:0071824	86	0.032
developmental programmed cell death	GO:0010623	138	0.031
intracellular receptor signaling pathway	GO:0030522	19	0.031
nuclear transport	GO:0051169	72	0.031
regulation of chromatin organization	GO:1902275	32	0.031
appendage morphogenesis	GO:0035107	397	0.031
growth	GO:0040007	359	0.031
leg disc morphogenesis	GO:0007478	80	0.030
nucleoside triphosphate catabolic process	GO:0009143	108	0.029
negative regulation of signaling	GO:0023057	219	0.029
renal system development	GO:0072001	72	0.028
embryonic organ development	GO:0048568	50	0.028
organic substance catabolic process	GO:1901575	308	0.028
positive regulation of protein metabolic process	GO:0051247	128	0.027
ribose phosphate metabolic process	GO:0019693	145	0.027
positive regulation of protein modification process	GO:0031401	58	0.027
cellular amino acid metabolic process	GO:0006520	61	0.027
cellular nitrogen compound catabolic process	GO:0044270	165	0.027
regulation of ras protein signal transduction	GO:0046578	93	0.026
intracellular signal transduction	GO:0035556	300	0.026
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	119	0.026
single organism membrane organization	GO:0044802	93	0.025
dna conformation change	GO:0071103	105	0.025
g2 dna damage checkpoint	GO:0031572	69	0.024
mitotic cell cycle phase transition	GO:0044772	138	0.024
nucleobase containing compound catabolic process	GO:0034655	165	0.024
organophosphate catabolic process	GO:0046434	112	0.024
mitotic dna integrity checkpoint	GO:0044774	75	0.024
positive regulation of phosphate metabolic process	GO:0045937	139	0.024
cytoskeleton dependent cytokinesis	GO:0061640	81	0.023
regulation of response to gamma radiation	GO:2001228	4	0.023
response to organic substance	GO:0010033	284	0.023
axis specification	GO:0009798	167	0.023
positive regulation of cellular amino acid metabolic process	GO:0045764	0	0.023
regulation of intracellular protein transport	GO:0033157	46	0.023
regulation of cellular catabolic process	GO:0031329	157	0.023
regulation of transferase activity	GO:0051338	58	0.022
negative regulation of chromosome organization	GO:2001251	19	0.022	Human
reproductive behavior	GO:0019098	122	0.022	Worm
protein targeting	GO:0006605	64	0.022
purine containing compound catabolic process	GO:0072523	112	0.022
establishment of protein localization to organelle	GO:0072594	62	0.022
regulation of apoptotic process	GO:0042981	130	0.022
mitotic cell cycle embryonic	GO:0045448	38	0.022
nucleocytoplasmic transport	GO:0006913	72	0.021
positive regulation of proteolysis	GO:0045862	52	0.021
dna methylation or demethylation	GO:0044728	4	0.021
regulation of compound eye cone cell fate specification	GO:0042682	4	0.021
cellular macromolecular complex assembly	GO:0034622	153	0.021
regulation of hemocyte proliferation	GO:0035206	37	0.021
negative regulation of neurogenesis	GO:0050768	53	0.021
positive regulation of cellular component biogenesis	GO:0044089	80	0.020
regulation of microtubule based process	GO:0032886	49	0.020
hematopoietic or lymphoid organ development	GO:0048534	57	0.020
regulation of protein transport	GO:0051223	57	0.020
regulation of cell differentiation	GO:0045595	302	0.020
negative regulation of catalytic activity	GO:0043086	42	0.020
regulation of protein phosphorylation	GO:0001932	64	0.020
regulation of cellular component biogenesis	GO:0044087	201	0.020
nucleoside phosphate catabolic process	GO:1901292	110	0.020
regulation of cell fate specification	GO:0042659	27	0.020
regulation of transport	GO:0051049	181	0.019
r3 r4 cell differentiation	GO:0048056	12	0.019
ribonucleotide catabolic process	GO:0009261	109	0.019
dna alkylation	GO:0006305	4	0.019
hemopoiesis	GO:0030097	46	0.019
axon choice point recognition	GO:0016198	26	0.019
homeostatic process	GO:0042592	199	0.019
regulation of cell fate commitment	GO:0010453	29	0.019
cellular macromolecule catabolic process	GO:0044265	136	0.019
regulation of purine nucleotide metabolic process	GO:1900542	62	0.019
digestive tract development	GO:0048565	149	0.018
regulation of neurogenesis	GO:0050767	158	0.018
ribonucleoside monophosphate metabolic process	GO:0009161	51	0.018
regulation of protein import into nucleus	GO:0042306	28	0.018
regulation of neuron differentiation	GO:0045664	103	0.018
response to sterol	GO:0036314	34	0.018
regulation of mitotic cell cycle	GO:0007346	190	0.018
post embryonic appendage morphogenesis	GO:0035120	385	0.017
jnk cascade	GO:0007254	50	0.017
regulation of programmed cell death	GO:0043067	152	0.017
response to ketone	GO:1901654	34	0.017
protein processing	GO:0016485	68	0.017
regulation of purine nucleotide catabolic process	GO:0033121	48	0.017
tube morphogenesis	GO:0035239	191	0.017
cellular component assembly involved in morphogenesis	GO:0010927	151	0.017
mitotic g2 m transition checkpoint	GO:0044818	70	0.017
negative regulation of multicellular organismal process	GO:0051241	142	0.017
nucleosome mobilization	GO:0042766	9	0.016
striated muscle cell development	GO:0055002	50	0.016
regulation of embryonic development	GO:0045995	68	0.016
cell proliferation	GO:0008283	299	0.016
digestive tract morphogenesis	GO:0048546	127	0.016
intracellular protein transport	GO:0006886	104	0.016
regulation of response to stress	GO:0080134	200	0.016
regulation of histone modification	GO:0031056	20	0.016
cellular response to organic substance	GO:0071310	132	0.016
regulation of multicellular organismal development	GO:2000026	414	0.016
histone h3 k27 methylation	GO:0070734	6	0.016
cellular response to endogenous stimulus	GO:0071495	80	0.016
regulation of cellular response to stress	GO:0080135	89	0.016
multi organism reproductive behavior	GO:0044705	121	0.016	Worm
tissue migration	GO:0090130	155	0.016
negative regulation of proteolysis	GO:0045861	31	0.015
positive regulation of catabolic process	GO:0009896	105	0.015
sister chromatid segregation	GO:0000819	92	0.015
protein modification by small protein conjugation	GO:0032446	79	0.015
negative regulation of phosphate metabolic process	GO:0045936	45	0.015
actin filament based process	GO:0030029	220	0.015
atp metabolic process	GO:0046034	49	0.015
actomyosin structure organization	GO:0031032	56	0.015
humoral immune response	GO:0006959	117	0.015
organonitrogen compound catabolic process	GO:1901565	128	0.015
regulation of protein targeting	GO:1903533	29	0.015
regulation of ras gtpase activity	GO:0032318	38	0.014
compound eye retinal cell programmed cell death	GO:0046667	23	0.014
negative regulation of protein metabolic process	GO:0051248	85	0.014
photoreceptor cell development	GO:0042461	96	0.014
cellular protein complex assembly	GO:0043623	71	0.014
epithelial tube morphogenesis	GO:0060562	88	0.014
compound eye photoreceptor fate commitment	GO:0001752	36	0.014
regulation of phosphatase activity	GO:0010921	3	0.014
regulation of proteasomal ubiquitin dependent protein catabolic process	GO:0032434	37	0.014
segmentation	GO:0035282	207	0.014
purine nucleoside monophosphate metabolic process	GO:0009126	50	0.014
pupal development	GO:0035209	11	0.013
dna packaging	GO:0006323	91	0.013
catabolic process	GO:0009056	409	0.013
regulation of embryonic cell shape	GO:0016476	30	0.013
regulation of localization	GO:0032879	275	0.013	Human
regulation of intracellular transport	GO:0032386	64	0.013
histone h4 k16 acetylation	GO:0043984	4	0.013
camera type eye development	GO:0043010	4	0.013
regulation of nucleocytoplasmic transport	GO:0046822	35	0.013
locomotory behavior	GO:0007626	176	0.013
proteolysis	GO:0006508	192	0.012
nucleobase containing small molecule metabolic process	GO:0055086	174	0.012
regulation of retinal cell programmed cell death	GO:0046668	18	0.012
dna templated transcriptional preinitiation complex assembly	GO:0070897	20	0.012
maternal determination of dorsal ventral axis ovarian follicular epithelium germ line encoded	GO:0008070	2	0.012
guanosine containing compound metabolic process	GO:1901068	74	0.012
positive regulation of immune system process	GO:0002684	68	0.012
compound eye cone cell fate commitment	GO:0042676	5	0.012
wing disc morphogenesis	GO:0007472	344	0.012
spindle checkpoint	GO:0031577	11	0.012
axon midline choice point recognition	GO:0016199	26	0.012
macromolecule deacylation	GO:0098732	11	0.012
eye photoreceptor cell fate commitment	GO:0042706	37	0.012
male gamete generation	GO:0048232	201	0.012
taxis	GO:0042330	304	0.012
dorsal vessel heart proper cell fate commitment	GO:0035053	2	0.012
axonogenesis	GO:0007409	290	0.012
ovarian follicle cell development	GO:0030707	248	0.012
ribonucleoside monophosphate catabolic process	GO:0009158	39	0.012
epidermis development	GO:0008544	65	0.012
histone deacetylation	GO:0016575	9	0.012
organic cyclic compound catabolic process	GO:1901361	168	0.012
negative regulation of protein processing	GO:0010955	31	0.012
chemical homeostasis	GO:0048878	92	0.012
positive regulation of nucleoside metabolic process	GO:0045979	47	0.011
embryonic hemopoiesis	GO:0035162	26	0.011
regulation of protein localization	GO:0032880	76	0.011	Human
chromosome organization involved in meiosis	GO:0070192	10	0.011
negative regulation of chromatin silencing	GO:0031936	9	0.011
negative regulation of protein modification process	GO:0031400	29	0.011
retina development in camera type eye	GO:0060041	4	0.011
negative regulation of phosphorylation	GO:0042326	35	0.011
response to organic cyclic compound	GO:0014070	89	0.011
oviposition	GO:0018991	19	0.011	Worm
mitochondrial membrane organization	GO:0007006	3	0.011
wnt signaling pathway	GO:0016055	98	0.011
genitalia development	GO:0048806	26	0.011
cytoplasmic transport	GO:0016482	130	0.011
regulation of striated muscle contraction	GO:0006942	2	0.010
ecdysone mediated induction of salivary gland cell autophagic cell death	GO:0035072	12	0.010
regulation of proteasomal protein catabolic process	GO:0061136	39	0.010
negative regulation of histone methylation	GO:0031061	3	0.010
response to endogenous stimulus	GO:0009719	119	0.010
phagocytosis	GO:0006909	215	0.010
establishment of ommatidial planar polarity	GO:0042067	49	0.010
protein phosphorylation	GO:0006468	169	0.010
regulation of nucleoside metabolic process	GO:0009118	50	0.010
phosphorylation	GO:0016310	294	0.010
cellular amine metabolic process	GO:0044106	12	0.010
protein catabolic process	GO:0030163	101	0.010

wapl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of cellular proliferation	DOID:14566	0.188
organ system cancer	DOID:0050686	0.055
cancer	DOID:162	0.055

Loading network...

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network