Drosophila melanogaster

115 known processes

ird5 (Dmel_CG4201)

immune response deficient 5

(Aliases: Ikkbeta,DIK,ird5/DmIkk[beta],Dmel\CG4201,Dmikkbeta,IKKb,DmIKKb,Ird-5,dIKK,IKKbeta,Lak,dIKK-beta,Ird5,DmIKKbeta,DmIkkbeta,IKKB,IKK,ird,IKK-beta,DLAK,DmIKK,IK,DmIKKBeta,ikk,anon-89Bd,IRD-5,LRK,dLak,CG4201,Ik,dmIKKbeta)

ird5 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of biosynthetic process of antibacterial peptides active against gram positive bacteriaGO:000281630.997
humoral immune responseGO:00069591170.993
antibacterial humoral responseGO:0019731440.991
positive regulation of defense response to virus by hostGO:0002230100.970
immune responseGO:00069552460.966
positive regulation of antibacterial peptide productionGO:0002803200.962
regulation of defense response to virus by hostGO:0050691100.958
regulation of biosynthetic process of antibacterial peptides active against gram negative bacteriaGO:0002813140.952
positive regulation of antimicrobial humoral responseGO:0002760280.950
regulation of antibacterial peptide biosynthetic processGO:0002808220.930
antibacterial peptide productionGO:0002778220.925
regulation of defense response to virusGO:0050688140.924
positive regulation of antibacterial peptide biosynthetic processGO:0006963200.923
antimicrobial peptide productionGO:0002775460.923
immune system processGO:00023763470.918
positive regulation of antimicrobial peptide productionGO:0002225280.917
regulation of defense response to bacteriumGO:1900424300.908
antimicrobial humoral responseGO:0019730990.906
defense response to virusGO:0051607230.904
antibacterial peptide biosynthetic processGO:0002780220.903
regulation of antibacterial peptide productionGO:0002786220.900
antifungal peptide productionGO:000278170.894
positive regulation of biosynthetic process of antibacterial peptides active against gram negative bacteriaGO:0006964120.876
biosynthetic process of antibacterial peptides active against gram negative bacteriaGO:0002812140.851
defense response to bacteriumGO:00427421780.851
regulation of response to external stimulusGO:00321011150.840
peptidoglycan recognition protein signaling pathwayGO:0061057160.838
immune effector processGO:0002252980.834
defense response to other organismGO:00985422250.825
peptide metabolic processGO:0006518800.819
regulation of antimicrobial peptide productionGO:0002784440.815
positive regulation of humoral immune responseGO:0002922280.792
antifungal humoral responseGO:0019732120.761
response to peptidoglycanGO:003249420.749
regulation of response to biotic stimulusGO:0002831630.738
positive regulation of response to biotic stimulusGO:0002833310.737
regulation of immune effector processGO:0002697520.722
regulation of humoral immune responseGO:0002920510.716
regulation of multi organism processGO:00439001310.716
response to external biotic stimulusGO:00432072930.715
cellular amide metabolic processGO:0043603800.685
positive regulation of immune effector processGO:0002699280.677
regulation of antimicrobial humoral responseGO:0002759500.661
biosynthetic process of antibacterial peptides active against gram positive bacteriaGO:000281530.658
regulation of cellular amide metabolic processGO:0034248390.649
positive regulation of antifungal peptide biosynthetic processGO:000696750.641
response to biotic stimulusGO:00096072940.632
regulation of production of molecular mediator of immune responseGO:0002700440.631
response to bacteriumGO:00096171980.628
positive regulation of antimicrobial peptide biosynthetic processGO:0002807260.625
regulation of antimicrobial peptide biosynthetic processGO:0002805380.623
defense responseGO:00069523000.607
positive regulation of response to external stimulusGO:0032103440.605
regulation of immune responseGO:00507761180.600
antimicrobial peptide biosynthetic processGO:0002777380.594
defense response to gram negative bacteriumGO:0050829940.585
response to other organismGO:00517072930.574
response to virusGO:0009615280.566
production of molecular mediator of immune responseGO:0002440460.526
negative regulation of peptidoglycan recognition protein signaling pathwayGO:006106030.427
regulation of defense responseGO:00313471020.401
positive regulation of cellular amide metabolic processGO:0034250260.320
cellular protein modification processGO:00064644380.313
positive regulation of defense response to bacteriumGO:1900426230.302
amide biosynthetic processGO:0043604420.282
positive regulation of biosynthetic process of antibacterial peptides active against gram positive bacteriaGO:000696530.280
positive regulation of production of molecular mediator of immune responseGO:0002702280.280
positive regulation of defense responseGO:0031349590.274
regulation of i kappab kinase nf kappab signalingGO:004312220.266
Zebrafish Mouse
positive regulation of immune responseGO:0050778630.228
activation of innate immune responseGO:000221840.210
regulation of peptidoglycan recognition protein signaling pathwayGO:006105840.207
regulation of antifungal peptide productionGO:000278860.199
regulation of endopeptidase activityGO:0052548360.191
Fly
regulation of innate immune responseGO:0045088710.190
positive regulation of endopeptidase activityGO:0010950260.189
Fly
regulation of antifungal peptide biosynthetic processGO:000281050.189
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280230.189
Fly
cellular response to external stimulusGO:0071496660.185
cellular response to extracellular stimulusGO:0031668640.183
regulation of immune system processGO:00026821760.183
innate immune responseGO:00450871440.181
positive regulation of multi organism processGO:0043902400.181
negative regulation of gene expressionGO:00106293870.175
peptide biosynthetic processGO:0043043420.173
organonitrogen compound metabolic processGO:19015643180.166
gene silencing by rnaGO:0031047570.161
positive regulation of biosynthetic processGO:00098913160.159
cognitionGO:00508901410.155
organonitrogen compound biosynthetic processGO:19015661170.151
antifungal peptide biosynthetic processGO:000278350.149
establishment of localization in cellGO:00516494020.147
Fly
protein localizationGO:00081042840.145
response to extracellular stimulusGO:00099911160.143
cell cycle checkpointGO:0000075950.136
regulation of response to stressGO:00801342000.136
chromosome organizationGO:00512763600.132
immune response regulating signaling pathwayGO:000276420.132
establishment of protein localizationGO:00451841630.129
intracellular signal transductionGO:00355563000.129
Zebrafish Mouse
cellular response to mechanical stimulusGO:007126020.128
regulation of defense response to fungusGO:190015060.127
pigmentationGO:0043473750.126
positive regulation of antifungal peptide productionGO:000280460.125
response to nutrient levelsGO:00316671140.122
regulation of cell cycleGO:00517262910.121
dendrite morphogenesisGO:00488131990.121
single organism intracellular transportGO:19025822070.120
Fly
mitotic dna integrity checkpointGO:0044774750.120
defense response to gram positive bacteriumGO:0050830410.119
negative regulation of defense response to bacteriumGO:190042570.113
cellularizationGO:0007349900.110
negative regulation of cellular metabolic processGO:00313243820.109
deathGO:00162652840.108
Zebrafish Rat Fly
negative regulation of cell cycle phase transitionGO:19019881030.107
small rna loading onto riscGO:007092260.106
imaginal disc derived appendage morphogenesisGO:00351143950.106
regulation of cellular protein metabolic processGO:00322682430.105
Fly
posttranscriptional regulation of gene expressionGO:00106081450.104
response to lipopolysaccharideGO:003249640.104
immune response activating signal transductionGO:000275720.104
response to starvationGO:0042594970.104
positive regulation of immune system processGO:0002684680.101
organelle assemblyGO:00709251980.098
programmed cell deathGO:00125012570.097
Zebrafish Fly
catabolic processGO:00090564090.093
activation of cysteine type endopeptidase activity involved in apoptotic processGO:0006919160.093
reactive oxygen species metabolic processGO:0072593220.092
internal peptidyl lysine acetylationGO:0018393380.090
heterochromatin organizationGO:0070828250.088
innate immune response activating signal transductionGO:000275820.088
positive regulation of response to stimulusGO:00485843230.086
rna interferenceGO:0016246270.085
gene silencingGO:00164581380.085
regulation of intracellular signal transductionGO:19025312360.085
Human Zebrafish Mouse
cell deathGO:00082192790.081
Zebrafish Rat Fly
negative regulation of stem cell proliferationGO:2000647300.081
cytoplasmic transportGO:00164821300.079
dna metabolic processGO:00062592270.078
signal transduction in response to dna damageGO:004277030.077
regulation of cell differentiationGO:00455953020.077
negative regulation of cell communicationGO:00106482230.076
Zebrafish
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281250.075
Fly
chromatin organizationGO:00063252070.074
activation of cysteine type endopeptidase activityGO:0097202170.074
melanization defense responseGO:0035006450.072
cellular macromolecule localizationGO:00707272200.072
lipopolysaccharide mediated signaling pathwayGO:003166310.071
response to organophosphorusGO:004668320.071
regulation of cell deathGO:00109411730.071
Zebrafish Rat Fly
regulation of macroautophagyGO:0016241150.070
dna integrity checkpointGO:0031570810.070
developmental maturationGO:00217001720.070
Fly
nuclear transportGO:0051169720.069
regulation of programmed cell deathGO:00430671520.068
Zebrafish Fly
regulation of protein metabolic processGO:00512462560.068
Fly
cellular catabolic processGO:00442483720.067
maintenance of protein location in cellGO:0032507260.066
response to abiotic stimulusGO:00096283410.065
positive regulation of cellular biosynthetic processGO:00313283160.064
positive regulation of cell deathGO:0010942690.064
Rat Fly
protein transportGO:00150311550.064
secondary metabolic processGO:0019748750.063
single organism catabolic processGO:00447122280.062
fat soluble vitamin metabolic processGO:000677510.062
zymogen activationGO:0031638200.061
negative regulation of signalingGO:00230572190.060
Zebrafish
cellular protein localizationGO:00346131600.059
pigment metabolic processGO:0042440840.059
negative regulation of mitotic cell cycleGO:00459301090.059
i kappab kinase nf kappab signalingGO:000724960.058
Zebrafish Mouse
mitotic spindle organizationGO:00070522200.057
pattern recognition receptor signaling pathwayGO:000222120.057
benzene containing compound metabolic processGO:004253730.056
positive regulation of multicellular organismal processGO:00512401430.055
regulation of peptidase activityGO:0052547390.054
Fly
cardiovascular system developmentGO:0072358820.053
internal protein amino acid acetylationGO:0006475380.053
dendrite developmentGO:00163582040.053
protein localization to nucleusGO:0034504550.053
regulation of gene expression epigeneticGO:00400291280.053
regulation of cell cycle processGO:00105641810.053
positive regulation of cell communicationGO:00106472500.052
Mouse
intracellular transportGO:00469072280.052
Fly
cellular response to dna damage stimulusGO:00069742230.052
protein complex assemblyGO:00064612000.052
regulation of nucleocytoplasmic transportGO:0046822350.052
mucosal immune responseGO:0002385100.052
nucleocytoplasmic transportGO:0006913720.051
macromolecular complex assemblyGO:00650032560.051
positive regulation of protein transportGO:0051222370.050
negative regulation of response to stimulusGO:00485852580.050
Zebrafish
regulation of cellular response to stressGO:0080135890.050
organic substance transportGO:00717022570.049
salivary gland morphogenesisGO:00074351450.049
regulation of mitotic cell cycleGO:00073461900.049
positive regulation of nitrogen compound metabolic processGO:00511733540.049
cellular response to lipopolysaccharideGO:007122230.049
posttranscriptional gene silencing by rnaGO:0035194450.049
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.048
cellular response to starvationGO:0009267610.048
microtubule organizing center organizationGO:00310231680.048
response to woundingGO:0009611940.048
dna damage checkpointGO:0000077780.047
positive regulation of proteolysisGO:0045862520.047
Fly
cellular response to abiotic stimulusGO:0071214580.047
positive regulation of macromolecule metabolic processGO:00106044050.047
Human Fly
g2 dna damage checkpointGO:0031572690.047
gastrulation involving germ band extensionGO:0010004360.047
melanin metabolic processGO:0006582470.046
developmental programmed cell deathGO:00106231380.046
regulation of autophagyGO:0010506620.045
head involutionGO:0008258350.045
response to organonitrogen compoundGO:0010243750.045
regulation of establishment of protein localizationGO:0070201610.045
positive regulation of signalingGO:00230562430.043
Mouse
organic substance catabolic processGO:19015753080.043
histolysisGO:00075591020.043
response to organic cyclic compoundGO:0014070890.042
regulation of mitotic cell cycle phase transitionGO:19019901300.042
apoptotic signaling pathwayGO:0097190270.042
tissue deathGO:00162711020.042
chitin based cuticle sclerotizationGO:0007593190.041
response to organic substanceGO:00100332840.041
Human Rat
regulation of intracellular transportGO:0032386640.041
regulation of multicellular organismal developmentGO:20000264140.040
jnk cascadeGO:0007254500.040
positive regulation of cellular component organizationGO:00511301560.040
positive regulation of molecular functionGO:00440931360.040
Human Mouse Rat Fly
nf kappab import into nucleusGO:004234810.040
extrinsic apoptotic signaling pathwayGO:009719110.040
organelle fissionGO:00482853400.040
positive regulation of gene expressionGO:00106282900.039
Human
regulation of catalytic activityGO:00507901850.039
Fly
cellular response to molecule of bacterial originGO:007121930.038
protein modification processGO:00362114380.038
single organism cellular localizationGO:19025801800.038
salivary gland cell autophagic cell deathGO:0035071830.038
posttranscriptional gene silencingGO:0016441460.037
regulation of cytoplasmic transportGO:1903649470.037
negative regulation of rna biosynthetic processGO:19026792400.037
phagocytosisGO:00069092150.037
salivary gland histolysisGO:0035070880.037
defense response to fungusGO:0050832480.037
regulation of intracellular protein transportGO:0033157460.037
apoptotic processGO:00069151590.036
Zebrafish Fly
regulation of cell cycle phase transitionGO:19019871300.036
positive regulation of cellular catabolic processGO:0031331950.036
cellular response to biotic stimulusGO:007121640.036
response to temperature stimulusGO:00092661060.036
cell proliferationGO:00082832990.036
Mouse Rat
negative regulation of cell cycle processGO:00109481090.036
gland morphogenesisGO:00226121450.036
cellular response to organic substanceGO:00713101320.036
Human
regulation of gene silencingGO:0060968630.036
post embryonic appendage morphogenesisGO:00351203850.035
courtship behaviorGO:0007619680.035
cellular response to oxygen containing compoundGO:1901701790.034
macromolecule catabolic processGO:00090571610.034
response to fungusGO:0009620500.034
cellular response to dsrnaGO:0071359150.034
regulation of cellular localizationGO:00603411360.034
heterocycle catabolic processGO:00467001660.034
mitotic cell cycle phase transitionGO:00447721380.034
compound eye morphogenesisGO:00017452490.034
regulation of protein import into nucleusGO:0042306280.033
neuron remodelingGO:0016322290.033
Fly
protein complex biogenesisGO:00702712010.033
production of small rna involved in gene silencing by rnaGO:0070918150.033
single organism behaviorGO:00447083910.033
imaginal disc derived wing morphogenesisGO:00074763370.033
protein targeting to nucleusGO:0044744510.033
regulation of nf kappab import into nucleusGO:004234510.033
response to radiationGO:00093141550.033
negative regulation of rna metabolic processGO:00512532510.033
regulation of molecular functionGO:00650092170.033
Human Mouse Rat Fly
regulation of catabolic processGO:00098941700.032
proteolysisGO:00065081920.032
Fly
membrane organizationGO:00610241120.032
regulation of transportGO:00510491810.032
Mouse
neurological system processGO:00508773580.032
regulation of cellular component biogenesisGO:00440872010.032
memoryGO:0007613940.032
negative regulation of response to external stimulusGO:0032102220.031
protein localization to organelleGO:0033365820.031
regulation of cellular catabolic processGO:00313291570.031
negative regulation of cellular biosynthetic processGO:00313272770.031
male mating behaviorGO:0060179700.030
salivary gland developmentGO:00074311620.030
regulation of response to woundingGO:1903034190.030
nuclear divisionGO:00002803320.030
negative regulation of signal transductionGO:00099682060.030
Zebrafish
positive regulation of cell cycle processGO:0090068280.030
retinal cell programmed cell deathGO:0046666250.029
wing disc morphogenesisGO:00074723440.029
response to nitrogen compoundGO:1901698900.029
organ or tissue specific immune responseGO:0002251100.029
autophagyGO:00069141080.029
single organism nuclear importGO:1902593510.029
protein targetingGO:0006605640.029
cell cycle phase transitionGO:00447701400.029
negative regulation of cell cycleGO:00457861160.029
positive regulation of transportGO:0051050920.028
Mouse
regulation of jnk cascadeGO:0046328400.028
central nervous system developmentGO:00074172010.028
Zebrafish
developmental pigmentationGO:0048066680.028
regulation of localizationGO:00328792750.028
Mouse
endocytosisGO:00068973100.028
lysosomal transportGO:0007041130.028
response to alkaloidGO:0043279260.028
positive regulation of protein import into nucleusGO:0042307210.028
response to unfolded proteinGO:000698690.028
mitotic dna damage checkpointGO:0044773740.028
chromosome segregationGO:00070591570.027
stem cell proliferationGO:0072089880.027
protein maturationGO:0051604710.027
dsrna fragmentationGO:0031050150.027
dorsal closureGO:0007391790.027
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178650.027
positive regulation of peptidase activityGO:0010952290.027
Fly
response to dsrnaGO:0043331150.026
cellular response to organic cyclic compoundGO:0071407320.026
nitrogen compound transportGO:0071705850.026
digestive tract developmentGO:00485651490.026
Zebrafish
autophagic cell deathGO:0048102830.026
apoptotic process involved in developmentGO:1902742200.026
regulation of cysteine type endopeptidase activityGO:2000116270.026
Fly
transcription from rna polymerase ii promoterGO:00063663680.026
Human
neuromuscular synaptic transmissionGO:0007274670.026
peptidyl amino acid modificationGO:00181931050.026
nuclear importGO:0051170510.026
histone acetylationGO:0016573380.026
embryonic development via the syncytial blastodermGO:00017001480.025
cuticle developmentGO:0042335860.025
intracellular protein transportGO:00068861040.025
negative regulation of nucleobase containing compound metabolic processGO:00459342610.025
cell divisionGO:00513012480.025
Fly
positive regulation of nucleobase containing compound metabolic processGO:00459353320.025
Human
protein acylationGO:0043543420.025
rna processingGO:00063961470.025
sperm individualizationGO:0007291480.025
regulation of protein localizationGO:0032880760.025
chromatin silencingGO:0006342760.024
organic hydroxy compound metabolic processGO:1901615830.024
regulation of hydrolase activityGO:0051336970.024
Fly
pigment biosynthetic processGO:0046148360.024
mitotic g2 m transition checkpointGO:0044818700.024
fat soluble vitamin biosynthetic processGO:004236210.024
negative regulation of transcription dna templatedGO:00458922370.024
negative regulation of biosynthetic processGO:00098902770.024
spindle organizationGO:00070512530.024
agingGO:00075681430.024
regulation of wnt signaling pathwayGO:0030111680.024
pole cell developmentGO:0007277260.024
cellular macromolecule catabolic processGO:00442651360.024
gastrulation with mouth forming firstGO:0001703360.023
negative regulation of protein metabolic processGO:0051248850.023
negative regulation of macromolecule biosynthetic processGO:00105582700.023
mitotic cell cycle checkpointGO:0007093880.023
regulation of developmental growthGO:00486381740.023
neural retina developmentGO:000340740.023
protein importGO:0017038550.023
stress activated mapk cascadeGO:0051403520.023
regulation of phosphorylationGO:00423251470.023
chromatin modificationGO:00165681470.023
protein modification by small protein conjugation or removalGO:00706471060.023
peripheral nervous system developmentGO:0007422520.023
regulation of transcription from rna polymerase ii promoterGO:00063573780.023
Human
gland developmentGO:00487321910.023
Mouse
negative regulation of immune responseGO:0050777390.022
regulation of synapse organizationGO:00508071100.022
telencephalon developmentGO:002153720.022
detection of light stimulusGO:0009583580.022
positive regulation of innate immune responseGO:0045089380.022
digestive system developmentGO:00551231490.022
Zebrafish
oocyte dorsal ventral axis specificationGO:0007310340.022
positive regulation of catabolic processGO:00098961050.022
cellular response to chemical stimulusGO:00708871990.022
Human
macroautophagyGO:0016236420.022
regionalizationGO:00030024160.022
Zebrafish
peptidyl lysine modificationGO:0018205570.022
positive regulation of cellular protein metabolic processGO:00322701180.021
Fly
regulation of growthGO:00400082330.021
response to endogenous stimulusGO:00097191190.021
positive regulation of rna biosynthetic processGO:19026802660.021
Human
segment polarity determinationGO:0007367250.021
heterochromatin organization involved in chromatin silencingGO:007086890.020
protein import into nucleusGO:0006606510.020
positive regulation of intracellular signal transductionGO:19025331160.020
Mouse
synaptic growth at neuromuscular junctionGO:00511241190.020
positive regulation of catalytic activityGO:00430851180.020
Fly
spindle assemblyGO:0051225800.020
positive regulation of nucleocytoplasmic transportGO:0046824240.020
organic cyclic compound catabolic processGO:19013611680.020
negative regulation of nitrogen compound metabolic processGO:00511722650.020
positive regulation of apoptotic signaling pathwayGO:200123540.020
ectopic germ cell programmed cell deathGO:003523480.020
regulation of cell cycle g1 s phase transitionGO:1902806230.020
connective tissue developmentGO:006144830.020
response to oxidative stressGO:0006979860.020
male gamete generationGO:00482322010.020
dorsal ventral axis specificationGO:0009950660.020
respiratory system developmentGO:00605412130.020
Fly
positive regulation of rna metabolic processGO:00512542710.019
Human
appendage developmentGO:00487364010.019
positive regulation of i kappab kinase nf kappab signalingGO:004312310.019
Mouse
embryonic morphogenesisGO:00485982060.019
Zebrafish
regulation of nuclear divisionGO:0051783580.019
response to lipidGO:0033993380.019
Rat
enzyme linked receptor protein signaling pathwayGO:00071671790.019
negative regulation of cellular component organizationGO:00511291080.019
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.019
Human
interspecies interaction between organismsGO:0044419160.019
forebrain developmentGO:003090020.019
positive regulation of apoptotic processGO:0043065470.019
Fly
positive regulation of growthGO:0045927750.019
positive regulation of hydrolase activityGO:0051345780.019
Fly
embryonic pattern specificationGO:00098801740.019
Zebrafish
negative regulation of nucleic acid templated transcriptionGO:19035072400.019
sensory organ morphogenesisGO:00905962600.019
detection of abiotic stimulusGO:0009582660.019
compound eye retinal cell programmed cell deathGO:0046667230.019
regulation of stress activated protein kinase signaling cascadeGO:0070302420.019
cellular response to sterol depletionGO:007150130.019
establishment of tissue polarityGO:0007164870.018
regulation of proteolysisGO:0030162870.018
Fly
positive regulation of cell cycleGO:0045787430.018
regulation of mapk cascadeGO:0043408920.018
regulation of reactive oxygen species metabolic processGO:200037780.018
apoptotic cell clearanceGO:0043277140.018
alternative mrna splicing via spliceosomeGO:0000380600.018
neuron maturationGO:0042551310.018
Fly
vesicle mediated transportGO:00161923810.018
Fly
myotube cell developmentGO:001490430.018
spermatid developmentGO:0007286980.018
mitotic nuclear divisionGO:00070672130.017
cellular response to nutrient levelsGO:0031669620.017
locomotory behaviorGO:00076261760.017
regulation of apoptotic processGO:00429811300.017
Zebrafish Fly
cellular amino acid metabolic processGO:0006520610.017
positive regulation of intracellular transportGO:0032388420.017
negative regulation of mitotic cell cycle phase transitionGO:19019911030.017
microtubule cytoskeleton organization involved in mitosisGO:1902850520.017
cellular nitrogen compound catabolic processGO:00442701650.017
ncrna metabolic processGO:0034660430.017
mating behaviorGO:00076171060.017
embryo development ending in birth or egg hatchingGO:00097921520.017
Zebrafish
mrna metabolic processGO:00160711240.017
exocrine system developmentGO:00352721620.017
cellular response to nitrogen compoundGO:1901699510.017
positive regulation of macromolecule biosynthetic processGO:00105572830.017
Human
protein processingGO:0016485680.017
germ line stem cell maintenanceGO:0030718500.016
nucleobase containing compound transportGO:0015931560.016
regulation of epithelial cell differentiationGO:003085640.016
peptidyl lysine acetylationGO:0018394390.016
response to copper ionGO:004668840.016
imaginal disc fusionGO:0046528190.016
regulation of protein transportGO:0051223570.016
limb developmentGO:006017310.016
cation transportGO:00068121100.016
Mouse
spermatogenesisGO:00072832000.016
positive regulation of developmental growthGO:0048639620.016
positive regulation of developmental processGO:00510941430.016
camera type eye developmentGO:004301040.016
cell cycle arrestGO:000705040.016
centrosome duplicationGO:00512981210.016
negative regulation of innate immune responseGO:0045824300.016
covalent chromatin modificationGO:00165691060.016
regulation of synaptic growth at neuromuscular junctionGO:0008582890.015
regulation of ras gtpase activityGO:0032318380.015
positive regulation of cell migrationGO:003033520.015
regulation of response to extracellular stimulusGO:0032104180.015
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stressGO:007005940.015
cellular response to ethanolGO:007136140.015
regulation of anatomical structure morphogenesisGO:00226032420.015
vitamin metabolic processGO:000676620.015
positive regulation of phosphate metabolic processGO:00459371390.015
small gtpase mediated signal transductionGO:0007264880.015
endomembrane system organizationGO:00102561190.015
appendage morphogenesisGO:00351073970.015
retina development in camera type eyeGO:006004140.015
molting cycle chitin based cuticleGO:0007591560.015
cell cell signaling involved in cell fate commitmentGO:00451682100.015
membrane depolarizationGO:005189940.015
response to ethanolGO:0045471590.015
morphogenesis of an epitheliumGO:00020092760.015
Zebrafish Mouse
negative regulation of growthGO:0045926840.015
negative regulation of cell differentiationGO:00455961430.015
negative regulation of cell deathGO:0060548810.015
Zebrafish
regulation of synapse structure and activityGO:00508031280.015
muscle cell differentiationGO:00426921030.015

ird5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.077
cancerDOID:16200.018
disease of cellular proliferationDOID:1456600.018
organ system cancerDOID:005068600.016