Drosophila melanogaster

170 known processes

Caf1 (Dmel_CG4236)

Chromatin assembly factor 1 subunit

(Aliases: Caf1p55,NURF-55,NURF,CG4236,dCAF-1,p55/NURF-55,CAF1,RbAp48,dCAF-1 p55,Caf1/p55,Nurf55,d-CAF1,P55,CAF1p55,Nurf-55,caf1,Caf-1,154659_at,p55,Dmel\CG4236,NURF55,CAF1-55,dNURF,CAF-1,55,p55CAF1,Nurf,caf-1,MSI1/RbAp48/CAC3/LIN-53,caf1 p55)

Caf1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
nucleosome organizationGO:0034728590.991
cellular response to dna damage stimulusGO:00069742230.989
protein dna complex subunit organizationGO:0071824860.984
positive regulation of rna biosynthetic processGO:19026802660.927
mitotic g2 m transition checkpointGO:0044818700.857
eye developmentGO:00016543230.810
posttranscriptional gene silencingGO:0016441460.787
Worm
histone modificationGO:00165701060.779
chromosome organizationGO:00512763600.773
negative regulation of macromolecule biosynthetic processGO:00105582700.768
chromatin modificationGO:00165681470.766
regulation of gene expression epigeneticGO:00400291280.757
regulation of response to stressGO:00801342000.732
cell cycle checkpointGO:0000075950.730
dna damage checkpointGO:0000077780.719
positive regulation of nitrogen compound metabolic processGO:00511733540.716
negative regulation of cell cycle phase transitionGO:19019881030.711
dna integrity checkpointGO:0031570810.709
chromatin organizationGO:00063252070.691
g2 dna damage checkpointGO:0031572690.676
positive regulation of nucleic acid templated transcriptionGO:19035082660.631
transcription from rna polymerase ii promoterGO:00063663680.567
regulation of intracellular signal transductionGO:19025312360.556
gene silencingGO:00164581380.544
protein localization to nucleusGO:0034504550.542
negative regulation of transcription dna templatedGO:00458922370.537
dna metabolic processGO:00062592270.509
negative regulation of mitotic cell cycle phase transitionGO:19019911030.498
positive regulation of response to stimulusGO:00485843230.496
negative regulation of biosynthetic processGO:00098902770.468
mitotic g2 dna damage checkpointGO:0007095690.451
intracellular signal transductionGO:00355563000.441
regulation of transcription from rna polymerase ii promoterGO:00063573780.397
positive regulation of developmental processGO:00510941430.392
regulation of cellular response to stressGO:0080135890.390
regulation of mitotic cell cycleGO:00073461900.378
regulation of sister chromatid cohesionGO:000706320.363
single organism nuclear importGO:1902593510.346
aromatic compound catabolic processGO:00194391660.340
Human
cell deathGO:00082192790.330
Worm
mitotic dna damage checkpointGO:0044773740.325
negative regulation of nucleobase containing compound metabolic processGO:00459342610.318
protein localization to chromatinGO:007116830.316
covalent chromatin modificationGO:00165691060.312
positive regulation of biosynthetic processGO:00098913160.310
establishment of localization in cellGO:00516494020.310
negative regulation of cell cycle processGO:00109481090.296
regulation of cell proliferationGO:00421271630.294
negative regulation of rna metabolic processGO:00512532510.292
positive regulation of phosphate metabolic processGO:00459371390.287
single organism intracellular transportGO:19025822070.286
chromatin remodelingGO:0006338720.283
mitotic dna integrity checkpointGO:0044774750.279
response to oxygen containing compoundGO:19017002000.277
positive regulation of signal transductionGO:00099672230.276
protein targeting to nucleusGO:0044744510.268
regulation of cellular amino acid metabolic processGO:000652100.267
positive regulation of gene expressionGO:00106282900.265
regulation of programmed cell deathGO:00430671520.264
camera type eye developmentGO:004301040.263
compound eye photoreceptor cell differentiationGO:00017511400.254
atp dependent chromatin remodelingGO:0043044220.251
Human
regulation of cellular ketone metabolic processGO:001056530.239
gene silencing by rnaGO:0031047570.233
Worm
body morphogenesisGO:001017120.231
negative regulation of gene expression epigeneticGO:0045814770.227
programmed cell deathGO:00125012570.224
Worm
negative regulation of gene expressionGO:00106293870.214
positive regulation of cell developmentGO:0010720610.210
positive regulation of macromolecule metabolic processGO:00106044050.209
positive regulation of transcription dna templatedGO:00458932660.208
negative regulation of mitotic cell cycleGO:00459301090.203
epithelial cell differentiationGO:00308553220.202
proteolysis involved in cellular protein catabolic processGO:0051603830.201
mitotic cell cycle phase transitionGO:00447721380.200
rna interferenceGO:0016246270.199
Worm
regionalizationGO:00030024160.199
nuclear importGO:0051170510.177
mitotic cell cycle checkpointGO:0007093880.175
small molecule metabolic processGO:00442813050.172
Human
regulation of cell deathGO:00109411730.170
compound eye developmentGO:00487493070.170
skin developmentGO:0043588650.166
posttranscriptional gene silencing by rnaGO:0035194450.163
Worm
positive regulation of cellular biosynthetic processGO:00313283160.161
peptidyl lysine methylationGO:0018022160.156
regulation of phosphorylationGO:00423251470.155
cellular macromolecule catabolic processGO:00442651360.153
positive regulation of macromolecule biosynthetic processGO:00105572830.150
negative regulation of signal transductionGO:00099682060.148
regulation of cell cycle processGO:00105641810.148
regulation of cell cycle g1 s phase transitionGO:1902806230.147
response to ionizing radiationGO:0010212320.144
cell cycle phase transitionGO:00447701400.138
negative regulation of cell proliferationGO:0008285690.135
cell proliferationGO:00082832990.132
nuclear divisionGO:00002803320.130
developmental growthGO:00485892800.130
Zebrafish
negative regulation of intracellular signal transductionGO:1902532570.130
organonitrogen compound metabolic processGO:19015643180.123
Human
meiotic cell cycle processGO:19030461320.121
cellular response to chemical stimulusGO:00708871990.121
organic acid metabolic processGO:00060821030.121
nucleosome mobilizationGO:004276690.118
negative regulation of wnt signaling pathwayGO:0030178280.116
protein dna complex assemblyGO:0065004630.115
positive regulation of multicellular organismal processGO:00512401430.114
muscle structure developmentGO:00610612240.112
embryo development ending in birth or egg hatchingGO:00097921520.112
Worm
regulation of protein metabolic processGO:00512462560.112
cellular response to organic substanceGO:00713101320.111
regulation of dna metabolic processGO:0051052340.110
apoptotic processGO:00069151590.110
Worm
negative regulation of nitrogen compound metabolic processGO:00511722650.105
regulation of cellular amine metabolic processGO:003323830.104
negative regulation of cellular metabolic processGO:00313243820.104
organophosphate metabolic processGO:00196371950.103
Human
protein modification processGO:00362114380.103
negative regulation of signalingGO:00230572190.103
cellular response to ionizing radiationGO:0071479150.103
mitotic spindle organizationGO:00070522200.102
regulation of g1 s transition of mitotic cell cycleGO:2000045230.101
organic substance catabolic processGO:19015753080.101
Human
notch signaling pathwayGO:00072191200.100
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.099
single organism cellular localizationGO:19025801800.098
positive regulation of phosphorylationGO:0042327870.094
regulation of mitotic cell cycle phase transitionGO:19019901300.093
nucleoside triphosphate catabolic processGO:00091431080.093
Human
meiotic nuclear divisionGO:00071261510.092
histone h4 k16 acetylationGO:004398440.090
intermediate filament cytoskeleton organizationGO:004510410.090
positive regulation of cellular protein metabolic processGO:00322701180.088
purine ribonucleoside catabolic processGO:00461301120.087
Human
phosphorylationGO:00163102940.087
positive regulation of catalytic activityGO:00430851180.085
compound eye morphogenesisGO:00017452490.085
positive regulation of nucleobase containing compound metabolic processGO:00459353320.085
negative regulation of nucleic acid templated transcriptionGO:19035072400.083
double strand break repairGO:0006302260.081
eye morphogenesisGO:00485922600.080
negative regulation of developmental processGO:00510932010.079
Worm
vesicle mediated transportGO:00161923810.078
positive regulation of rna metabolic processGO:00512542710.077
peptidyl lysine acetylationGO:0018394390.077
negative regulation of apoptotic processGO:0043066630.077
posttranscriptional regulation of gene expressionGO:00106081450.076
Worm
negative regulation of cellular biosynthetic processGO:00313272770.076
dna repairGO:0006281540.075
regulation of phosphorus metabolic processGO:00511742100.075
carboxylic acid metabolic processGO:0019752920.073
heterocycle catabolic processGO:00467001660.072
Human
regulation of multicellular organismal developmentGO:20000264140.072
Worm
ribonucleoside triphosphate metabolic processGO:00091991190.071
Human
catabolic processGO:00090564090.070
Human
gliogenesisGO:0042063800.069
ecdysone mediated induction of salivary gland cell autophagic cell deathGO:0035072120.069
regulation of cellular localizationGO:00603411360.068
negative regulation of cell deathGO:0060548810.068
meiotic cell cycleGO:00513211710.066
regulation of apoptotic processGO:00429811300.065
protein import into nucleusGO:0006606510.065
response to organic substanceGO:00100332840.065
Rat
protein catabolic processGO:00301631010.064
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.064
positive regulation of cell communicationGO:00106472500.063
meiosis iGO:0007127590.062
intracellular steroid hormone receptor signaling pathwayGO:0030518120.061
modification dependent macromolecule catabolic processGO:0043632790.061
terminal button organizationGO:0072553190.061
growthGO:00400073590.061
Human Zebrafish
cellular protein localizationGO:00346131600.060
modification dependent protein catabolic processGO:0019941780.059
regulation of nervous system developmentGO:00519602480.059
regulation of phosphate metabolic processGO:00192202100.058
regulation of growthGO:00400082330.058
Human
regulation of cell cycle phase transitionGO:19019871300.057
chromatin silencingGO:0006342760.056
blastoderm segmentationGO:00073501590.056
regulation of establishment of protein localizationGO:0070201610.055
cellular response to oxygen containing compoundGO:1901701790.055
purine nucleotide catabolic processGO:00061951090.054
Human
regulation of intracellular protein transportGO:0033157460.054
nucleotide metabolic processGO:00091171610.053
Human
positive regulation of cellular amine metabolic processGO:003324000.052
nucleocytoplasmic transportGO:0006913720.051
phagocytosisGO:00069092150.049
ubiquitin dependent protein catabolic processGO:0006511780.048
muscle organ developmentGO:00075171270.048
positive regulation of phosphorus metabolic processGO:00105621390.048
cellular protein modification processGO:00064644380.047
response to radiationGO:00093141550.047
regulation of mapk cascadeGO:0043408920.046
chromatin assemblyGO:0031497480.046
carbohydrate derivative metabolic processGO:19011352170.046
Human
nucleobase containing compound catabolic processGO:00346551650.046
Human
positive regulation of signalingGO:00230562430.046
oxoacid metabolic processGO:00434361030.046
regulation of protein localization to nucleusGO:1900180290.045
organelle fissionGO:00482853400.045
protein localizationGO:00081042840.045
purine nucleoside monophosphate metabolic processGO:0009126500.044
Human
establishment of protein localization to organelleGO:0072594620.043
retina development in camera type eyeGO:006004140.042
nucleoside triphosphate metabolic processGO:00091411200.042
Human
regulation of cell differentiationGO:00455953020.042
negative regulation of response to stimulusGO:00485852580.042
nucleoside phosphate metabolic processGO:00067531620.042
Human
leg disc developmentGO:0035218920.042
purine ribonucleotide catabolic processGO:00091541090.041
Human
regulation of catabolic processGO:00098941700.041
positive regulation of protein modification processGO:0031401580.040
positive regulation of intracellular transportGO:0032388420.040
cellular amine metabolic processGO:0044106120.040
histone exchangeGO:0043486210.040
regulation of developmental growthGO:00486381740.039
positive regulation of cellular amino acid metabolic processGO:004576400.039
regulation of localizationGO:00328792750.039
amine metabolic processGO:0009308120.039
regulation of neural precursor cell proliferationGO:2000177350.039
negative regulation of cell cycleGO:00457861160.038
dna templated transcription elongationGO:0006354180.038
dna replication initiationGO:000627060.037
positive regulation of intracellular signal transductionGO:19025331160.037
positive regulation of molecular functionGO:00440931360.036
response to sterolGO:0036314340.036
chromosome segregationGO:00070591570.036
positive regulation of cell proliferationGO:0008284470.036
sensory organ morphogenesisGO:00905962600.035
cellular amino acid metabolic processGO:0006520610.035
peptidyl amino acid modificationGO:00181931050.035
regulation of phosphatase activityGO:001092130.035
cellular catabolic processGO:00442483720.035
Human
internal protein amino acid acetylationGO:0006475380.034
induction of programmed cell death by hormonesGO:0035081120.034
apoptotic signaling pathwayGO:0097190270.033
forebrain developmentGO:003090020.033
purine nucleoside triphosphate catabolic processGO:00091461080.033
Human
camera type eye morphogenesisGO:004859320.033
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.032
dna conformation changeGO:00711031050.031
immune responseGO:00069552460.031
regulation of organelle organizationGO:00330431960.031
protein importGO:0017038550.031
hemopoiesisGO:0030097460.031
striated muscle tissue developmentGO:0014706270.031
regulation of response to dna damage stimulusGO:2001020230.031
regulation of protein import into nucleusGO:0042306280.030
regulation of nucleocytoplasmic transportGO:0046822350.030
regulation of intracellular transportGO:0032386640.029
positive regulation of protein import into nucleusGO:0042307210.029
positive regulation of protein phosphorylationGO:0001934340.029
mitochondrial membrane organizationGO:000700630.029
cellular ketone metabolic processGO:0042180240.029
ribonucleoside monophosphate metabolic processGO:0009161510.028
Human
negative regulation of transcription factor import into nucleusGO:004299240.028
regulation of cellular protein metabolic processGO:00322682430.028
cellular protein catabolic processGO:0044257830.027
axis specificationGO:00097981670.027
nuclear dna replicationGO:003326010.027
spindle organizationGO:00070512530.027
digestive tract developmentGO:00485651490.027
Worm
intracellular transportGO:00469072280.026
organ growthGO:0035265560.026
proteolysisGO:00065081920.026
regulation of mrna processingGO:0050684710.026
ribonucleoside triphosphate catabolic processGO:00092031080.026
Human
peptidyl lysine trimethylationGO:001802360.026
carbohydrate derivative catabolic processGO:19011361180.026
Human
peptidyl lysine modificationGO:0018205570.025
reproductive structure developmentGO:0048608740.025
Worm
negative regulation of multicellular organismal processGO:00512411420.025
Worm
cell growthGO:00160491080.025
Human
chromosome separationGO:0051304420.025
dna packagingGO:0006323910.024
regulation of transportGO:00510491810.024
regulation of notch signaling pathwayGO:00085931000.024
ribose phosphate metabolic processGO:00196931450.023
Human
regulation of imaginal disc growthGO:0045570260.023
regulation of cell cycleGO:00517262910.023
regulation of protein localizationGO:0032880760.023
tissue morphogenesisGO:00487292970.022
regulation of organ growthGO:0046620420.022
nuclear transportGO:0051169720.022
regulation of anatomical structure morphogenesisGO:00226032420.022
protein complex assemblyGO:00064612000.022
oocyte differentiationGO:00099941450.022
regulation of protein catabolic processGO:0042176550.022
macromolecule catabolic processGO:00090571610.022
purine ribonucleotide metabolic processGO:00091501450.022
Human
intracellular protein transportGO:00068861040.021
exocrine system developmentGO:00352721620.021
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630110.021
negative regulation of cell cycle g1 s phase transitionGO:1902807130.021
methylationGO:0032259470.021
negative regulation of cell differentiationGO:00455961430.020
mitotic sister chromatid segregationGO:0000070870.020
regulation of cytoplasmic transportGO:1903649470.020
organic cyclic compound catabolic processGO:19013611680.020
Human
gland developmentGO:00487321910.019
deathGO:00162652840.019
Worm
cell divisionGO:00513012480.019
cytoplasmic transportGO:00164821300.019
regulation of chromosome organizationGO:0033044640.019
ribonucleotide metabolic processGO:00092591450.019
Human
developmental programmed cell deathGO:00106231380.018
positive regulation of cell differentiationGO:0045597640.018
positive regulation of developmental growthGO:0048639620.018
negative regulation of immune system processGO:0002683500.018
negative regulation of programmed cell deathGO:0043069720.018
nucleobase containing small molecule metabolic processGO:00550861740.018
Human
male meiosisGO:0007140520.018
protein phosphorylationGO:00064681690.018
regulation of cellular component biogenesisGO:00440872010.018
regulation of cell developmentGO:00602842150.018
positive regulation of neurogenesisGO:0050769410.017
determination of left right symmetryGO:000736890.017
proteasomal protein catabolic processGO:0010498590.017
regulation of small gtpase mediated signal transductionGO:0051056930.017
hippo signalingGO:0035329200.017
purine ribonucleoside triphosphate metabolic processGO:00092051190.017
Human
asymmetric neuroblast division resulting in ganglion mother cell formationGO:005506020.016
digestive tract morphogenesisGO:00485461270.016
Worm
ribonucleotide catabolic processGO:00092611090.016
Human
ribonucleoside catabolic processGO:00424541120.016
Human
response to lipidGO:0033993380.016
Rat
intracellular receptor signaling pathwayGO:0030522190.016
embryonic pattern specificationGO:00098801740.016
histone acetylationGO:0016573380.016
peptidyl serine phosphorylationGO:001810570.016
peptidyl serine modificationGO:001820970.015
imaginal disc derived leg morphogenesisGO:0007480800.015
leg disc morphogenesisGO:0007478800.015
regulation of molecular functionGO:00650092170.015
glial cell differentiationGO:0010001350.015
nucleoside monophosphate metabolic processGO:0009123520.015
Human
positive regulation of bindingGO:005109940.015
spermatogenesisGO:00072832000.014
purine nucleoside triphosphate metabolic processGO:00091441190.014
Human
positive regulation of transportGO:0051050920.014
regulation of dna templated transcription elongationGO:0032784170.014
mapk cascadeGO:00001651070.014
reproductive system developmentGO:0061458740.014
Worm
purine nucleoside catabolic processGO:00061521120.014
Human
g1 s transition of mitotic cell cycleGO:0000082310.014
regulation of multicellular organism growthGO:0040014400.014
tricarboxylic acid metabolic processGO:007235010.014
negative regulation of rna biosynthetic processGO:19026792400.013
regulation of cellular protein catabolic processGO:1903362440.013
chromatin assembly or disassemblyGO:0006333520.013
intrinsic apoptotic signaling pathwayGO:0097193160.013
protein modification by small protein conjugation or removalGO:00706471060.013
positive regulation of protein localization to nucleusGO:1900182210.013
positive regulation of nucleocytoplasmic transportGO:0046824240.013
regulation of proteolysisGO:0030162870.013
digestive system developmentGO:00551231490.013
Worm
epidermal cell differentiationGO:0009913510.013
transcription elongation from rna polymerase ii promoterGO:0006368180.013
cellular response to lipidGO:0071396200.013
negative regulation of cell communicationGO:00106482230.012
positive regulation of i kappab kinase nf kappab signalingGO:004312310.012
positive regulation of protein metabolic processGO:00512471280.012
limb developmentGO:006017310.012
hematopoietic or lymphoid organ developmentGO:0048534570.012
gene silencing by mirnaGO:0035195220.012
small gtpase mediated signal transductionGO:0007264880.012
glycosyl compound metabolic processGO:19016571270.012
Human
regulation of multi organism processGO:00439001310.012
anatomical structure homeostasisGO:0060249970.012
positive regulation of epidermal growth factor activated receptor activityGO:004574110.012
protein localization to organelleGO:0033365820.012
taxisGO:00423303040.012
ncrna metabolic processGO:0034660430.012
production of mirnas involved in gene silencing by mirnaGO:0035196100.012
mitotic sister chromatid separationGO:0051306300.012
nucleoside catabolic processGO:00091641120.012
Human
dorsal ventral axis specificationGO:0009950660.011
macromolecular complex assemblyGO:00650032560.011
single organism catabolic processGO:00447122280.011
Human
cytokinesisGO:0000910900.011
negative regulation of gtp catabolic processGO:003312510.011
negative regulation of notch signaling pathwayGO:0045746410.011
regulation of mitosisGO:0007088560.011
negative regulation of nucleotide metabolic processGO:004598040.011
tube morphogenesisGO:00352391910.011
Worm
dna templated transcription initiationGO:0006352250.011
atp catabolic processGO:0006200380.011
Human
negative regulation of nucleoside metabolic processGO:004597810.011
instar larval developmentGO:0002168550.011
organic substance transportGO:00717022570.011
negative regulation of g1 s transition of mitotic cell cycleGO:2000134130.010
regulation of chromatin organizationGO:1902275320.010
response to alcoholGO:0097305950.010
regulation of wnt signaling pathwayGO:0030111680.010
multicellular organismal reproductive behaviorGO:00330571100.010
nitric oxide metabolic processGO:004620910.010
regulation of jnk cascadeGO:0046328400.010
chemotaxisGO:00069352490.010
negative regulation of purine nucleotide catabolic processGO:003312210.010
regulation of protein deacetylationGO:009031120.010
regulation of canonical wnt signaling pathwayGO:0060828150.010

Caf1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
organ system cancerDOID:005068600.055
disease of cellular proliferationDOID:1456600.055
cancerDOID:16200.055
bone development diseaseDOID:008000600.012
bone diseaseDOID:008000100.012
disease of anatomical entityDOID:700.012
connective tissue diseaseDOID:6500.012
dysostosisDOID:193400.012
brachydactylyDOID:005058100.012
musculoskeletal system diseaseDOID:1700.012