Drosophila melanogaster

370 known processes

scrib (Dmel_CG42614)

scribbled

(Aliases: CT17324,CG42614,Dmel\CG42614,l(3)j7B3,vart,MENE (3R)-F,Scrib,l(3)S042405,smi97B,l(3)c00119,0424/05,Scb,Scrb,CG5462,ird15,CG5467,l(3)673,Dmel_CG5462,ird,Dmel_CG5467,SCR)

scrib biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
establishment of planar polarityGO:0001736870.994
immune responseGO:00069552460.942
dendrite developmentGO:00163582040.917
morphogenesis of a polarized epitheliumGO:0001738930.894
cell cell junction organizationGO:0045216550.888
eye developmentGO:00016543230.879
dendrite morphogenesisGO:00488131990.828
eye morphogenesisGO:00485922600.803
cell proliferationGO:00082832990.802
humoral immune responseGO:00069591170.791
cell cell junction assemblyGO:0007043380.771
negative regulation of cell proliferationGO:0008285690.769
cell junction organizationGO:0034330570.745
establishment of tissue polarityGO:0007164870.703
establishment of epithelial cell apical basal polarityGO:0045198100.694
epithelial cell differentiationGO:00308553220.683
establishment of ommatidial planar polarityGO:0042067490.669
compound eye developmentGO:00487493070.660
vesicle mediated transportGO:00161923810.659
open tracheal system developmentGO:00074242040.650
peripheral nervous system developmentGO:0007422520.623
cell junction assemblyGO:0034329420.623
sensory organ morphogenesisGO:00905962600.622
regulation of dendrite morphogenesisGO:0048814280.593
regulation of cell differentiationGO:00455953020.580
compound eye photoreceptor developmentGO:0042051780.541
negative regulation of organ growthGO:0046621150.529
male gamete generationGO:00482322010.480
regulation of organ growthGO:0046620420.463
head developmentGO:00603221350.454
chemosensory behaviorGO:00076351060.439
regulation of cell proliferationGO:00421271630.439
lateral inhibitionGO:00463312060.427
positive regulation of endopeptidase activityGO:0010950260.413
spermatogenesisGO:00072832000.411
eye photoreceptor cell differentiationGO:00017541450.389
negative regulation of epithelial cell proliferationGO:005068040.368
single organismal cell cell adhesionGO:0016337450.342
imaginal disc growthGO:0007446370.341
regulation of imaginal disc growthGO:0045570260.340
response to abiotic stimulusGO:00096283410.333
negative regulation of imaginal disc growthGO:004557180.330
actin cytoskeleton organizationGO:00300362060.324
positive regulation of peptidase activityGO:0010952290.312
compound eye photoreceptor cell differentiationGO:00017511400.305
establishment or maintenance of cell polarityGO:00071631670.294
regulation of epithelial cell proliferationGO:005067840.286
regulation of protein metabolic processGO:00512462560.274
lipid localizationGO:0010876540.262
proteolysisGO:00065081920.261
equator specificationGO:004531740.240
appendage developmentGO:00487364010.229
cellular catabolic processGO:00442483720.227
eye photoreceptor cell developmentGO:0042462810.223
single organism cell adhesionGO:0098602470.221
autophagyGO:00069141080.218
positive regulation of protein metabolic processGO:00512471280.212
organ growthGO:0035265560.209
respiratory system developmentGO:00605412130.205
endocytosisGO:00068973100.197
olfactory behaviorGO:0042048970.191
establishment of epithelial cell polarityGO:0090162130.190
spermatid differentiationGO:00485151140.190
cell divisionGO:00513012480.189
immune system processGO:00023763470.179
stem cell maintenanceGO:0019827670.177
imaginal disc derived wing hair organizationGO:0035317450.172
photoreceptor cell developmentGO:0042461960.171
single organism behaviorGO:00447083910.166
regulation of immune system processGO:00026821760.166
regulation of neurogenesisGO:00507671580.165
regulation of cellular protein metabolic processGO:00322682430.164
post embryonic appendage morphogenesisGO:00351203850.164
response to oxygen containing compoundGO:19017002000.163
columnar cuboidal epithelial cell differentiationGO:00020652560.162
asymmetric protein localizationGO:0008105330.159
negative regulation of response to stimulusGO:00485852580.151
regulation of tube architecture open tracheal systemGO:0035152680.150
non sensory hair organizationGO:0035316470.149
hippo signalingGO:0035329200.147
regulation of cell cycle processGO:00105641810.137
morphogenesis of an epitheliumGO:00020092760.135
positive regulation of proteolysisGO:0045862520.134
establishment of imaginal disc derived wing hair orientationGO:0001737240.133
protein import into nucleusGO:0006606510.123
imaginal disc derived appendage morphogenesisGO:00351143950.117
cell cycle phase transitionGO:00447701400.116
photoreceptor cell differentiationGO:00465301700.115
asymmetric stem cell divisionGO:0098722490.108
tube developmentGO:00352952440.106
positive regulation of cellular component organizationGO:00511301560.105
striated muscle tissue developmentGO:0014706270.104
modification dependent macromolecule catabolic processGO:0043632790.102
wing disc morphogenesisGO:00074723440.100
peripheral nervous system neuron differentiationGO:004893480.099
actin filament based processGO:00300292200.099
regulation of multicellular organismal developmentGO:20000264140.098
macromolecule catabolic processGO:00090571610.095
intracellular signal transductionGO:00355563000.092
columnar cuboidal epithelial cell developmentGO:00020662490.087
cell adhesionGO:00071551360.087
regulation of endopeptidase activityGO:0052548360.086
muscle tissue developmentGO:0060537300.085
production of molecular mediator of immune responseGO:0002440460.085
epithelial cell developmentGO:00020642740.084
compound eye morphogenesisGO:00017452490.080
negative regulation of biosynthetic processGO:00098902770.079
regulation of immune responseGO:00507761180.078
regulation of phosphorus metabolic processGO:00511742100.077
regulation of multi organism processGO:00439001310.076
tissue morphogenesisGO:00487292970.076
stem cell divisionGO:0017145690.072
regulation of intracellular signal transductionGO:19025312360.072
protein catabolic processGO:00301631010.071
branching involved in open tracheal system developmentGO:0060446450.070
muscle organ developmentGO:00075171270.069
synapse assemblyGO:00074161430.069
mushroom body developmentGO:0016319700.069
positive regulation of immune system processGO:0002684680.068
organic substance transportGO:00717022570.068
regulation of phosphate metabolic processGO:00192202100.067
negative regulation of developmental processGO:00510932010.067
cellular protein catabolic processGO:0044257830.066
embryonic pattern specificationGO:00098801740.065
calcium dependent cell cell adhesion via plasma membrane cell adhesion moleculesGO:001633990.065
brain developmentGO:00074201200.064
regulation of hippo signalingGO:0035330140.064
proteasomal protein catabolic processGO:0010498590.064
negative regulation of signalingGO:00230572190.063
imaginal disc eversionGO:000756140.063
cellular protein modification processGO:00064644380.062
regulation of response to stressGO:00801342000.062
response to radiationGO:00093141550.061
negative regulation of signal transductionGO:00099682060.061
membrane organizationGO:00610241120.061
heterophilic cell cell adhesion via plasma membrane cell adhesion moleculesGO:000715780.060
signal transduction by phosphorylationGO:00230141070.059
positive regulation of cell deathGO:0010942690.059
protein modification processGO:00362114380.059
endomembrane system organizationGO:00102561190.059
regulation of innate immune responseGO:0045088710.058
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161540.056
regulation of cytoskeleton organizationGO:0051493890.056
cell cell adhesion mediated by cadherinGO:004433160.055
regulation of organelle organizationGO:00330431960.055
regulation of proteolysisGO:0030162870.055
establishment of spindle orientationGO:0051294180.055
hindbrain developmentGO:003090220.054
stem cell developmentGO:0048864790.054
regulation of protein modification processGO:00313991120.053
cellular macromolecule catabolic processGO:00442651360.053
r7 cell differentiationGO:0045466430.053
lipid storageGO:0019915380.052
ommatidial rotationGO:0016318200.052
regulation of phosphorylationGO:00423251470.051
transcription from rna polymerase ii promoterGO:00063663680.051
single organism intracellular transportGO:19025822070.051
asymmetric neuroblast divisionGO:0055059330.050
asymmetric cell divisionGO:0008356370.050
larval developmentGO:00021641040.049
establishment of apical basal cell polarityGO:0035089120.049
positive regulation of nucleobase containing compound metabolic processGO:00459353320.048
actin filament organizationGO:00070151260.048
antimicrobial humoral responseGO:0019730990.047
regionalizationGO:00030024160.047
establishment or maintenance of epithelial cell apical basal polarityGO:0045197240.047
zonula adherens assemblyGO:004518660.046
proteolysis involved in cellular protein catabolic processGO:0051603830.046
positive regulation of synaptic growth at neuromuscular junctionGO:0045887260.046
response to woundingGO:0009611940.045
imaginal disc derived appendage developmentGO:00487373990.045
regulation of neuroblast proliferationGO:1902692340.045
regulation of cell developmentGO:00602842150.044
positive regulation of nitrogen compound metabolic processGO:00511733540.044
negative regulation of molecular functionGO:0044092510.043
single organism cellular localizationGO:19025801800.041
positive regulation of cell differentiationGO:0045597640.041
protein transportGO:00150311550.041
germ line stem cell maintenanceGO:0030718500.040
cytoskeleton dependent cytokinesisGO:0061640810.040
imaginal disc derived leg morphogenesisGO:0007480800.040
negative regulation of cell communicationGO:00106482230.040
cellular response to extracellular stimulusGO:0031668640.039
regulation of catabolic processGO:00098941700.038
axonal fasciculationGO:0007413120.038
regulation of defense responseGO:00313471020.038
regulation of protein localizationGO:0032880760.038
germarium derived female germ line cyst formationGO:0030727420.038
regulation of tube size open tracheal systemGO:0035151430.038
regulation of pathway restricted smad protein phosphorylationGO:006039310.037
cell deathGO:00082192790.037
wound healingGO:0042060750.037
leg disc morphogenesisGO:0007478800.037
chromosome separationGO:0051304420.037
chromosome segregationGO:00070591570.036
rhabdomere developmentGO:0042052380.036
phosphorylationGO:00163102940.035
synaptic transmissionGO:00072682880.035
regulation of transcription from rna polymerase ii promoterGO:00063573780.035
establishment of localization in cellGO:00516494020.034
negative regulation of macromolecule biosynthetic processGO:00105582700.034
ubiquitin dependent protein catabolic processGO:0006511780.034
negative regulation of neuroblast proliferationGO:0007406270.034
neuroblast proliferationGO:0007405740.033
developmental maturationGO:00217001720.033
r3 r4 cell fate commitmentGO:0007464100.033
positive regulation of macromolecule metabolic processGO:00106044050.033
chemotaxisGO:00069352490.033
dorsal appendage formationGO:0046843470.032
positive regulation of cell cycle processGO:0090068280.032
tube morphogenesisGO:00352391910.032
phagocytosisGO:00069092150.032
regulation of tube length open tracheal systemGO:0035159240.032
cellular macromolecule localizationGO:00707272200.031
response to light stimulusGO:00094161240.031
muscle structure developmentGO:00610612240.031
mitotic cell cycle phase transitionGO:00447721380.031
regulation of cellular localizationGO:00603411360.031
cellular homeostasisGO:0019725800.031
r8 cell fate specificationGO:004546450.030
adherens junction organizationGO:0034332270.030
positive regulation of nervous system developmentGO:0051962690.030
negative regulation of developmental growthGO:0048640640.030
eye photoreceptor cell fate commitmentGO:0042706370.029
cell cell adhesionGO:0098609260.029
synapse organizationGO:00508081960.029
protein phosphorylationGO:00064681690.029
imaginal disc derived wing morphogenesisGO:00074763370.029
regulation of neuron differentiationGO:00456641030.029
regulation of cellular catabolic processGO:00313291570.029
dendrite self avoidanceGO:007059380.029
protein localizationGO:00081042840.028
positive regulation of phosphorus metabolic processGO:00105621390.028
regulation of nervous system developmentGO:00519602480.028
establishment or maintenance of monopolar cell polarityGO:0061339150.028
taxisGO:00423303040.028
apoptotic processGO:00069151590.028
torc1 signalingGO:0038202120.028
embryonic organ developmentGO:0048568500.028
establishment of protein localization to organelleGO:0072594620.028
regulation of peptidase activityGO:0052547390.027
neuron fate commitmentGO:0048663500.027
ovarian follicle cell developmentGO:00307072480.027
catabolic processGO:00090564090.027
regulation of cell adhesionGO:0030155270.026
histolysisGO:00075591020.026
regulation of cell cycle phase transitionGO:19019871300.026
meiotic cell cycle processGO:19030461320.026
protein targeting to nucleusGO:0044744510.026
regulation of response to biotic stimulusGO:0002831630.026
regulation of hydrolase activityGO:0051336970.025
negative regulation of cell differentiationGO:00455961430.025
positive regulation of signalingGO:00230562430.025
regulation of stem cell proliferationGO:0072091400.025
spermatid developmentGO:0007286980.024
chromatin organizationGO:00063252070.024
cellular response to external stimulusGO:0071496660.024
positive regulation of biosynthetic processGO:00098913160.023
axonogenesisGO:00074092900.023
metal ion transportGO:0030001740.022
organic substance catabolic processGO:19015753080.022
metal ion homeostasisGO:0055065440.022
regulation of molecular functionGO:00650092170.022
histoblast morphogenesisGO:000748890.021
chromosome organizationGO:00512763600.021
central nervous system developmentGO:00074172010.021
single organism membrane organizationGO:0044802930.021
apical constrictionGO:0003383180.021
mitotic sister chromatid separationGO:0051306300.021
negative regulation of stem cell proliferationGO:2000647300.021
myotube cell developmentGO:001490430.021
histone modificationGO:00165701060.021
protein kinase b signalingGO:004349110.020
cell cell signaling involved in cell fate commitmentGO:00451682100.020
regulation of transportGO:00510491810.020
instar larval developmentGO:0002168550.020
gland developmentGO:00487321910.020
innate immune responseGO:00450871440.020
negative regulation of cell cycleGO:00457861160.020
establishment of epithelial cell planar polarityGO:009016340.019
axon guidanceGO:00074112330.019
r3 r4 cell differentiationGO:0048056120.019
homeostatic processGO:00425921990.019
regulation of cell deathGO:00109411730.019
embryonic development via the syncytial blastodermGO:00017001480.019
single organism catabolic processGO:00447122280.019
establishment or maintenance of apical basal cell polarityGO:0035088340.019
regulation of cell cell adhesionGO:0022407210.019
regulation of protein transportGO:0051223570.019
developmental programmed cell deathGO:00106231380.019
regulation of cysteine type endopeptidase activityGO:2000116270.019
positive regulation of nucleic acid templated transcriptionGO:19035082660.019
positive regulation of apoptotic processGO:0043065470.019
growthGO:00400073590.018
blastoderm segmentationGO:00073501590.018
cytoplasmic transportGO:00164821300.018
synaptic growth at neuromuscular junctionGO:00511241190.018
regulation of chromosome organizationGO:0033044640.018
regulation of notch signaling pathwayGO:00085931000.018
negative regulation of notch signaling pathwayGO:0045746410.018
regulation of cell cycleGO:00517262910.018
regulation of actin cytoskeleton organizationGO:0032956420.018
positive regulation of i kappab kinase nf kappab signalingGO:004312310.018
embryonic morphogenesisGO:00485982060.017
morphogenesis of a branching structureGO:0001763450.017
positive regulation of cell cycleGO:0045787430.017
negative regulation of dendrite morphogenesisGO:005077420.017
divalent inorganic cation homeostasisGO:0072507290.017
regulation of establishment of protein localization to plasma membraneGO:009000370.017
establishment of body hair planar orientationGO:004810510.017
cytoplasm organizationGO:0007028640.017
glial cell developmentGO:0021782270.017
tissue deathGO:00162711020.016
response to biotic stimulusGO:00096072940.016
germarium derived oocyte fate determinationGO:0007294260.016
extrinsic apoptotic signaling pathwayGO:009719110.016
asymmetric protein localization involved in cell fate determinationGO:004516790.016
negative regulation of neural precursor cell proliferationGO:2000178270.016
establishment of spindle localizationGO:0051293220.016
regulation of establishment of planar polarityGO:0090175220.016
positive regulation of cell developmentGO:0010720610.016
response to other organismGO:00517072930.016
chaeta developmentGO:0022416970.016
cellular metal ion homeostasisGO:0006875310.016
response to organic substanceGO:00100332840.016
apical protein localizationGO:004517650.016
maintenance of locationGO:0051235730.016
positive regulation of organelle organizationGO:0010638650.015
regulation of cellular response to stressGO:0080135890.015
positive regulation of intracellular signal transductionGO:19025331160.015
dormancy processGO:002261120.015
regulation of organ morphogenesisGO:2000027780.015
negative regulation of protein metabolic processGO:0051248850.015
juvenile hormone mediated signaling pathwayGO:003562630.015
regulation of dendrite developmentGO:0050773370.015
regulation of programmed cell deathGO:00430671520.014
oocyte differentiationGO:00099941450.014
regulation of mitotic sister chromatid separationGO:0010965280.014
regulation of mitosisGO:0007088560.014
cellular divalent inorganic cation homeostasisGO:0072503230.014
regulation of protein deacetylationGO:009031120.014
regulation of jnk cascadeGO:0046328400.014
stem cell differentiationGO:00488631170.014
cellular protein localizationGO:00346131600.014
germ line stem cell divisionGO:0042078250.014
agingGO:00075681430.014
biological adhesionGO:00226101380.014
negative regulation of transforming growth factor beta receptor signaling pathwayGO:003051240.013
regulation of anatomical structure morphogenesisGO:00226032420.013
negative regulation of intracellular signal transductionGO:1902532570.013
ion homeostasisGO:0050801550.013
detection of stimulusGO:00516061560.013
establishment or maintenance of polarity of follicular epitheliumGO:0016334260.013
branching morphogenesis of an epithelial tubeGO:0048754450.013
positive regulation of phosphate metabolic processGO:00459371390.013
defense response to gram negative bacteriumGO:0050829940.013
nitrogen compound transportGO:0071705850.013
posttranscriptional regulation of gene expressionGO:00106081450.013
embryo development ending in birth or egg hatchingGO:00097921520.013
small gtpase mediated signal transductionGO:0007264880.013
regulation of cell junction assemblyGO:190188820.013
negative regulation of hippo signalingGO:003533150.013
epithelial cell migrationGO:00106311480.013
specification of organ identityGO:001009230.013
glial cell differentiationGO:0010001350.013
positive regulation of macromolecule biosynthetic processGO:00105572830.013
organelle inheritanceGO:004830820.013
positive regulation of developmental processGO:00510941430.013
immune effector processGO:0002252980.013
wnt signaling pathwayGO:0016055980.013
protein localization to organelleGO:0033365820.013
organic hydroxy compound metabolic processGO:1901615830.012
salivary gland histolysisGO:0035070880.012
leg disc developmentGO:0035218920.012
striated muscle cell differentiationGO:0051146900.012
protein localization to nucleusGO:0034504550.012
dna alkylationGO:000630540.012
regulation of catalytic activityGO:00507901850.012
positive regulation of cysteine type endopeptidase activityGO:2001056240.012
regulation of localizationGO:00328792750.012
neural precursor cell proliferationGO:0061351750.012
negative regulation of immune responseGO:0050777390.012
positive regulation of cell communicationGO:00106472500.012
positive regulation of rna biosynthetic processGO:19026802660.012
dna methylation or demethylationGO:004472840.012
tissue migrationGO:00901301550.012
heart developmentGO:0007507820.012
modification dependent protein catabolic processGO:0019941780.012
cellular response to oxygen containing compoundGO:1901701790.012
regulation of establishment of protein localizationGO:0070201610.012
cell recognitionGO:00080371020.012
zymogen activationGO:0031638200.012
basement membrane organizationGO:0071711100.012
body morphogenesisGO:001017120.012
positive regulation of molecular functionGO:00440931360.012
spindle organizationGO:00070512530.012
metaphase anaphase transition of cell cycleGO:0044784280.011
establishment of body hair or bristle planar orientationGO:004810460.011
negative regulation of catalytic activityGO:0043086420.011
deathGO:00162652840.011
positive regulation of protein localization to plasma membraneGO:190307830.011
regulation of antimicrobial humoral responseGO:0002759500.011
positive regulation of organ growthGO:0046622120.011
ras protein signal transductionGO:0007265880.011
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280230.011
establishment of mitotic spindle localizationGO:0040001170.011
morphogenesis of follicular epitheliumGO:0016333360.011
positive regulation of phosphorylationGO:0042327870.011
oxoacid metabolic processGO:00434361030.011
positive regulation of catalytic activityGO:00430851180.011
organonitrogen compound metabolic processGO:19015643180.011
positive regulation of catabolic processGO:00098961050.011
regulation of developmental pigmentationGO:0048070240.011
cation homeostasisGO:0055080510.010
cell cell adhesion via plasma membrane adhesion moleculesGO:0098742260.010
defense response to other organismGO:00985422250.010
chromatin modificationGO:00165681470.010
cell fate specificationGO:0001708710.010
regulation of cell divisionGO:0051302720.010
regulation of post embryonic developmentGO:0048580100.010
regulation of hemocyte proliferationGO:0035206370.010
ovarian follicle cell migrationGO:00072971210.010
regulation of cell morphogenesisGO:00226041630.010
nucleobase containing compound catabolic processGO:00346551650.010
regulation of mapk cascadeGO:0043408920.010
negative regulation of cellular biosynthetic processGO:00313272770.010
response to lipopolysaccharideGO:003249640.010
photoreceptor cell maintenanceGO:0045494110.010
positive regulation of response to stimulusGO:00485843230.010

scrib disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.015
auditory system diseaseDOID:274200.015
sensory system diseaseDOID:005015500.015
disease of anatomical entityDOID:700.015
nonsyndromic deafnessDOID:005056300.015