IMP: Integrative Multi-species Prediction

Drosophila melanogaster

131 known processes

Bap60 (Dmel_CG4303)

Brahma associated protein 60kD

(Aliases: Dmel\CG4303,i133,CG4303,BAPp60,i127,BAP60)

FLYBASE: FBgn0025463
Entrez: 32268
UniProtKB: Q9VYG2

Process Predictions
Disease Predictions

Bap60 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
cytoplasmic transport	GO:0016482	130	0.938
nuclear division	GO:0000280	332	0.861
negative regulation of cellular metabolic process	GO:0031324	382	0.850
embryo development ending in birth or egg hatching	GO:0009792	152	0.820	Worm
single organism cellular localization	GO:1902580	180	0.745
regionalization	GO:0003002	416	0.725
cellular protein modification process	GO:0006464	438	0.679
organelle fission	GO:0048285	340	0.569
neurological system process	GO:0050877	358	0.532
vesicle mediated transport	GO:0016192	381	0.523
intracellular signal transduction	GO:0035556	300	0.465
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.422
sex differentiation	GO:0007548	81	0.421	Worm
eye development	GO:0001654	323	0.409
reproductive system development	GO:0061458	74	0.409	Worm
catabolic process	GO:0009056	409	0.382
meiotic nuclear division	GO:0007126	151	0.365
single organism intracellular transport	GO:1902582	207	0.355
cellular catabolic process	GO:0044248	372	0.344
negative regulation of gene expression	GO:0010629	387	0.339
intracellular transport	GO:0046907	228	0.324
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.310
posttranscriptional regulation of gene expression	GO:0010608	145	0.309
morphogenesis of an epithelium	GO:0002009	276	0.292
cell cycle checkpoint	GO:0000075	95	0.289
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.275
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.252
cellular protein localization	GO:0034613	160	0.247
organic substance transport	GO:0071702	257	0.247
nucleocytoplasmic transport	GO:0006913	72	0.245
positive regulation of signaling	GO:0023056	243	0.240
posttranscriptional gene silencing by rna	GO:0035194	45	0.237
positive regulation of molecular function	GO:0044093	136	0.230
regulation of meiosis	GO:0040020	3	0.226
mrna metabolic process	GO:0016071	124	0.222
body morphogenesis	GO:0010171	2	0.217
cell death	GO:0008219	279	0.217
tissue morphogenesis	GO:0048729	297	0.214
respiratory system development	GO:0060541	213	0.213
autophagy	GO:0006914	108	0.210
organic cyclic compound catabolic process	GO:1901361	168	0.209
regulation of rna splicing	GO:0043484	69	0.206
positive regulation of response to stimulus	GO:0048584	323	0.203
death	GO:0016265	284	0.186
cell proliferation	GO:0008283	299	0.181
development of primary sexual characteristics	GO:0045137	50	0.178	Worm
positive regulation of cellular biosynthetic process	GO:0031328	316	0.177
cellular response to dna damage stimulus	GO:0006974	223	0.177
organic substance catabolic process	GO:1901575	308	0.157
regulation of transport	GO:0051049	181	0.157
response to radiation	GO:0009314	155	0.151
negative regulation of developmental process	GO:0051093	201	0.145
protein modification process	GO:0036211	438	0.145
regulation of cellular protein metabolic process	GO:0032268	243	0.141
chromatin modification	GO:0016568	147	0.132
response to extracellular stimulus	GO:0009991	116	0.125
covalent chromatin modification	GO:0016569	106	0.125
mrna splicing via spliceosome	GO:0000398	73	0.124
positive regulation of macromolecule metabolic process	GO:0010604	405	0.123
histone modification	GO:0016570	106	0.121
negative regulation of cell communication	GO:0010648	223	0.121
response to nutrient levels	GO:0031667	114	0.120
negative regulation of multicellular organismal process	GO:0051241	142	0.119
positive regulation of transport	GO:0051050	92	0.119
positive regulation of catalytic activity	GO:0043085	118	0.119
rna splicing	GO:0008380	83	0.118
homeostatic process	GO:0042592	199	0.116
cellular response to chemical stimulus	GO:0070887	199	0.116
apoptotic process	GO:0006915	159	0.111
retina development in camera type eye	GO:0060041	4	0.111
meiotic cell cycle	GO:0051321	171	0.109
dna integrity checkpoint	GO:0031570	81	0.108
cell division	GO:0051301	248	0.106
embryonic axis specification	GO:0000578	107	0.106
positive regulation of rna metabolic process	GO:0051254	271	0.105
memory	GO:0007613	94	0.103
positive regulation of biosynthetic process	GO:0009891	316	0.102
regulation of cell development	GO:0060284	215	0.101
dendrite morphogenesis	GO:0048813	199	0.099
protein transport	GO:0015031	155	0.094
segmentation	GO:0035282	207	0.092
regulation of intracellular signal transduction	GO:1902531	236	0.091
protein localization	GO:0008104	284	0.091
regulation of mrna splicing via spliceosome	GO:0048024	64	0.089
regulation of gene silencing	GO:0060968	63	0.086
blastoderm segmentation	GO:0007350	159	0.086
reproductive structure development	GO:0048608	74	0.085	Worm
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.084
cellular macromolecule localization	GO:0070727	220	0.082
negative regulation of cellular biosynthetic process	GO:0031327	277	0.081
embryonic development via the syncytial blastoderm	GO:0001700	148	0.080
open tracheal system development	GO:0007424	204	0.079
intracellular protein transport	GO:0006886	104	0.077
transcription from rna polymerase ii promoter	GO:0006366	368	0.071
chromatin organization	GO:0006325	207	0.070
central nervous system development	GO:0007417	201	0.069
rna processing	GO:0006396	147	0.068
mrna processing	GO:0006397	104	0.066
protein modification by small protein conjugation or removal	GO:0070647	106	0.065
regulation of protein metabolic process	GO:0051246	256	0.064
muscle structure development	GO:0061061	224	0.063
regulation of organelle organization	GO:0033043	196	0.059
cellular response to nutrient levels	GO:0031669	62	0.059
response to lipid	GO:0033993	38	0.058
positive regulation of erk1 and erk2 cascade	GO:0070374	36	0.057
dna damage checkpoint	GO:0000077	78	0.056
regulation of localization	GO:0032879	275	0.056
response to other organism	GO:0051707	293	0.055
cellular response to external stimulus	GO:0071496	66	0.055
regulation of mrna metabolic process	GO:1903311	72	0.053
compound eye development	GO:0048749	307	0.053
response to abiotic stimulus	GO:0009628	341	0.052
posttranscriptional gene silencing	GO:0016441	46	0.050
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.050
regulation of catalytic activity	GO:0050790	185	0.050
developmental growth	GO:0048589	280	0.049
protein targeting	GO:0006605	64	0.049
endocytosis	GO:0006897	310	0.049
immune response	GO:0006955	246	0.048
negative regulation of neural precursor cell proliferation	GO:2000178	27	0.048
regulation of gene expression epigenetic	GO:0040029	128	0.048	Human
positive regulation of signal transduction	GO:0009967	223	0.047
regulation of cell differentiation	GO:0045595	302	0.047
growth	GO:0040007	359	0.047
negative regulation of signaling	GO:0023057	219	0.046
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.045
oocyte development	GO:0048599	124	0.045
connective tissue development	GO:0061448	3	0.045
positive regulation of proteolysis	GO:0045862	52	0.044
epithelial cell migration	GO:0010631	148	0.044
programmed cell death	GO:0012501	257	0.044
cell motility	GO:0048870	251	0.044
mitotic g2 m transition checkpoint	GO:0044818	70	0.044
chromatin remodeling	GO:0006338	72	0.044
imaginal disc derived wing morphogenesis	GO:0007476	337	0.043
camera type eye development	GO:0043010	4	0.043
negative regulation of cell differentiation	GO:0045596	143	0.043
negative regulation of neurotransmitter secretion	GO:0046929	2	0.042
macromolecule catabolic process	GO:0009057	161	0.041
negative regulation of response to stimulus	GO:0048585	258	0.040
taxis	GO:0042330	304	0.040
gonad development	GO:0008406	50	0.038	Worm
chromosome organization	GO:0051276	360	0.038
response to light stimulus	GO:0009416	124	0.038
regulation of cell proliferation	GO:0042127	163	0.038
chromatin assembly or disassembly	GO:0006333	52	0.038
anterior posterior pattern specification	GO:0009952	136	0.038
establishment of localization in cell	GO:0051649	402	0.037
sensory organ morphogenesis	GO:0090596	260	0.037
positive regulation of multicellular organismal process	GO:0051240	143	0.037
response to endogenous stimulus	GO:0009719	119	0.037
dorsal ventral pattern formation	GO:0009953	133	0.036
nucleosome organization	GO:0034728	59	0.036	Human
response to organic substance	GO:0010033	284	0.035
positive regulation of phosphorus metabolic process	GO:0010562	139	0.035
protein localization to organelle	GO:0033365	82	0.035
signal transduction in response to dna damage	GO:0042770	3	0.034
stem cell differentiation	GO:0048863	117	0.034
tripartite regional subdivision	GO:0007351	103	0.034
establishment of protein localization	GO:0045184	163	0.034
nuclear transport	GO:0051169	72	0.034
rna splicing via transesterification reactions	GO:0000375	73	0.034
positive regulation of cell communication	GO:0010647	250	0.032
negative regulation of transcription dna templated	GO:0045892	237	0.032
cellular response to extracellular stimulus	GO:0031668	64	0.031
cellular response to organic substance	GO:0071310	132	0.031
regulation of intracellular transport	GO:0032386	64	0.031
regulation of immune system process	GO:0002682	176	0.030
negative regulation of cell cycle	GO:0045786	116	0.030
macromolecular complex assembly	GO:0065003	256	0.030
regulation of phosphorus metabolic process	GO:0051174	210	0.029
cellular response to starvation	GO:0009267	61	0.029
endomembrane system organization	GO:0010256	119	0.029
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.029
proteolysis involved in cellular protein catabolic process	GO:0051603	83	0.028
positive regulation of transcription dna templated	GO:0045893	266	0.028
histone acetylation	GO:0016573	38	0.028
regulation of multicellular organismal development	GO:2000026	414	0.028
positive regulation of rna biosynthetic process	GO:1902680	266	0.027
golgi organization	GO:0007030	66	0.027
jak stat cascade	GO:0007259	49	0.027
small molecule metabolic process	GO:0044281	305	0.026
gland development	GO:0048732	191	0.026
regulation of alternative mrna splicing via spliceosome	GO:0000381	60	0.025
phosphorylation	GO:0016310	294	0.025
positive regulation of gene expression	GO:0010628	290	0.025
regulation of chromatin organization	GO:1902275	32	0.024
cellular homeostasis	GO:0019725	80	0.024
gene silencing by rna	GO:0031047	57	0.024
developmental maturation	GO:0021700	172	0.024
axis specification	GO:0009798	167	0.024
protein processing	GO:0016485	68	0.024
negative regulation of rna metabolic process	GO:0051253	251	0.024
axonogenesis	GO:0007409	290	0.024
regulation of nervous system development	GO:0051960	248	0.024
regulation of catabolic process	GO:0009894	170	0.023
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.022
heart contraction	GO:0060047	26	0.021
cellular response to lipid	GO:0071396	20	0.021
protein phosphorylation	GO:0006468	169	0.021
g2 dna damage checkpoint	GO:0031572	69	0.021
dna repair	GO:0006281	54	0.021
regulation of meiotic cell cycle	GO:0051445	9	0.021
regulation of protein modification process	GO:0031399	112	0.021
larval development	GO:0002164	104	0.020	Worm
regulation of cellular localization	GO:0060341	136	0.020
regulation of nucleocytoplasmic transport	GO:0046822	35	0.020
single organism catabolic process	GO:0044712	228	0.020
fertilization	GO:0009566	26	0.020
gland morphogenesis	GO:0022612	145	0.020
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.020
dendrite development	GO:0016358	204	0.020
negative regulation of biosynthetic process	GO:0009890	277	0.019
protein catabolic process	GO:0030163	101	0.019
alternative mrna splicing via spliceosome	GO:0000380	60	0.019
protein modification by small protein conjugation	GO:0032446	79	0.019
regulation of response to stress	GO:0080134	200	0.019
imaginal disc derived appendage development	GO:0048737	399	0.018
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.018
embryonic morphogenesis	GO:0048598	206	0.018
anterior posterior axis specification	GO:0009948	109	0.018
formation of a compartment boundary	GO:0060288	4	0.018
molting cycle	GO:0042303	56	0.018
striated muscle cell differentiation	GO:0051146	90	0.018
mitotic cell cycle checkpoint	GO:0007093	88	0.018
response to alcohol	GO:0097305	95	0.018
epithelial structure maintenance	GO:0010669	17	0.018
anterior posterior axis specification embryo	GO:0008595	103	0.018
rna interference	GO:0016246	27	0.018
positive regulation of apoptotic signaling pathway	GO:2001235	4	0.017
embryonic organ development	GO:0048568	50	0.017
regulation of cell cycle process	GO:0010564	181	0.017
cognition	GO:0050890	141	0.017
negative regulation of intrinsic apoptotic signaling pathway	GO:2001243	1	0.017
mitotic dna integrity checkpoint	GO:0044774	75	0.017
regulation of mrna processing	GO:0050684	71	0.017
regulation of cellular response to stress	GO:0080135	89	0.017
positive regulation of nucleotide metabolic process	GO:0045981	55	0.017
protein deubiquitination	GO:0016579	17	0.016
negative regulation of cellular protein metabolic process	GO:0032269	85	0.016
cell fate specification	GO:0001708	71	0.016
dephosphorylation	GO:0016311	51	0.016
mrna 3 end processing	GO:0031124	28	0.016
protein import into nucleus	GO:0006606	51	0.016
cellular amide metabolic process	GO:0043603	80	0.016
positive regulation of nucleocytoplasmic transport	GO:0046824	24	0.016
regulation of apoptotic process	GO:0042981	130	0.016
phagocytosis	GO:0006909	215	0.016
regulation of transcription elongation from rna polymerase ii promoter	GO:0034243	15	0.015
mitotic g2 dna damage checkpoint	GO:0007095	69	0.015
regulation of developmental growth	GO:0048638	174	0.015
nucleoside catabolic process	GO:0009164	112	0.015
nuclear import	GO:0051170	51	0.015
protein modification by small protein removal	GO:0070646	28	0.015
protein acetylation	GO:0006473	39	0.015
negative regulation of cell cycle phase transition	GO:1901988	103	0.015
regulation of ras protein signal transduction	GO:0046578	93	0.014
regulation of molecular function	GO:0065009	217	0.014
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.014
purine ribonucleoside metabolic process	GO:0046128	127	0.014
positive regulation of phosphate metabolic process	GO:0045937	139	0.014
post embryonic appendage morphogenesis	GO:0035120	385	0.014
regulation of cell cycle	GO:0051726	291	0.014
response to starvation	GO:0042594	97	0.013
eye photoreceptor cell differentiation	GO:0001754	145	0.013
response to oxygen containing compound	GO:1901700	200	0.013
positive regulation of mapk cascade	GO:0043410	63	0.013
tube development	GO:0035295	244	0.013
head development	GO:0060322	135	0.013
signal transduction by phosphorylation	GO:0023014	107	0.013
cellular ketone metabolic process	GO:0042180	24	0.013
positive regulation of protein modification process	GO:0031401	58	0.013
oocyte dorsal ventral axis specification	GO:0007310	34	0.013
intracellular receptor signaling pathway	GO:0030522	19	0.013
protein import	GO:0017038	55	0.013
photoreceptor cell differentiation	GO:0046530	170	0.012
regulation of nuclear division	GO:0051783	58	0.012
regulation of phosphate metabolic process	GO:0019220	210	0.012
positive regulation of catabolic process	GO:0009896	105	0.012
protein complex biogenesis	GO:0070271	201	0.012
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.012
stem cell development	GO:0048864	79	0.012
immune system development	GO:0002520	57	0.012
regulation of protein modification by small protein conjugation or removal	GO:1903320	25	0.012
epithelial tube morphogenesis	GO:0060562	88	0.012
synaptic transmission	GO:0007268	288	0.012
negative regulation of purine nucleotide catabolic process	GO:0033122	1	0.012
peptidyl lysine modification	GO:0018205	57	0.012
positive regulation of gene expression epigenetic	GO:0045815	16	0.012	Human
blood circulation	GO:0008015	26	0.012
histone h2a acetylation	GO:0043968	1	0.012
eye morphogenesis	GO:0048592	260	0.012
digestive system development	GO:0055123	149	0.012
camera type eye morphogenesis	GO:0048593	2	0.012
cellular response to organic cyclic compound	GO:0071407	32	0.011
negative regulation of mitotic cell cycle	GO:0045930	109	0.011
diterpenoid biosynthetic process	GO:0016102	1	0.011
regulation of rac gtpase activity	GO:0032314	1	0.011
regulation of mitotic cell cycle	GO:0007346	190	0.011
protein ubiquitination	GO:0016567	70	0.011
appendage development	GO:0048736	401	0.011
protein maturation	GO:0051604	71	0.011
regulation of atp metabolic process	GO:1903578	6	0.011
negative regulation of rna biosynthetic process	GO:1902679	240	0.011
organonitrogen compound metabolic process	GO:1901564	318	0.011
nitrogen compound transport	GO:0071705	85	0.010
negative regulation of protein metabolic process	GO:0051248	85	0.010
aging	GO:0007568	143	0.010
macroautophagy	GO:0016236	42	0.010
carbohydrate derivative metabolic process	GO:1901135	217	0.010
golgi vesicle transport	GO:0048193	27	0.010
negative regulation of nucleotide metabolic process	GO:0045980	4	0.010
positive regulation of protein metabolic process	GO:0051247	128	0.010

Bap60 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of cellular proliferation	DOID:14566	0.091
disease of anatomical entity	DOID:7	0.055
cancer	DOID:162	0.048
organ system cancer	DOID:0050686	0.048
central nervous system disease	DOID:331	0.013
nervous system disease	DOID:863	0.013

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