IMP: Integrative Multi-species Prediction

Drosophila melanogaster

0 known processes

CG4769 (Dmel_CG4769)

CG4769 gene product from transcript CG4769-RA

(Aliases: anon-EST:Posey141,Dmel\CG4769)

Entrez: 38612
FLYBASE: FBgn0035600
UniProtKB: Q9VRL0

Process Predictions
Disease Predictions

CG4769 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
multicellular organismal aging	GO:0010259	140	0.633	Worm
embryo development ending in birth or egg hatching	GO:0009792	152	0.363	Worm
determination of adult lifespan	GO:0008340	137	0.267	Worm
organonitrogen compound metabolic process	GO:1901564	318	0.218	Yeast Worm
aging	GO:0007568	143	0.205	Worm
growth	GO:0040007	359	0.183
death	GO:0016265	284	0.156
embryonic morphogenesis	GO:0048598	206	0.155
localization of cell	GO:0051674	257	0.121
developmental growth	GO:0048589	280	0.109
regulation of multicellular organismal development	GO:2000026	414	0.100
larval development	GO:0002164	104	0.096	Worm
nucleoside triphosphate metabolic process	GO:0009141	120	0.095	Yeast Worm
small molecule metabolic process	GO:0044281	305	0.093	Yeast Worm
spermatogenesis	GO:0007283	200	0.092
organophosphate metabolic process	GO:0019637	195	0.090	Yeast Worm
cell motility	GO:0048870	251	0.089
organic acid metabolic process	GO:0006082	103	0.086
brain development	GO:0007420	120	0.081
cellular respiration	GO:0045333	26	0.079	Yeast
establishment of localization in cell	GO:0051649	402	0.074	Worm
cellular amino acid metabolic process	GO:0006520	61	0.073
head development	GO:0060322	135	0.068
regulation of cell development	GO:0060284	215	0.067
purine ribonucleoside metabolic process	GO:0046128	127	0.065	Yeast Worm
central nervous system development	GO:0007417	201	0.065
ribose phosphate metabolic process	GO:0019693	145	0.065	Yeast Worm
body morphogenesis	GO:0010171	2	0.063
cell proliferation	GO:0008283	299	0.057
gonad development	GO:0008406	50	0.057	Worm
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.054
oxoacid metabolic process	GO:0043436	103	0.053
programmed cell death	GO:0012501	257	0.051
glycosyl compound metabolic process	GO:1901657	127	0.051	Yeast Worm
positive regulation of biosynthetic process	GO:0009891	316	0.048
negative regulation of stem cell proliferation	GO:2000647	30	0.047
nucleoside phosphate metabolic process	GO:0006753	162	0.047	Yeast Worm
cell death	GO:0008219	279	0.046
ribonucleotide metabolic process	GO:0009259	145	0.046	Yeast Worm
regulation of cell differentiation	GO:0045595	302	0.046
tube development	GO:0035295	244	0.045
purine nucleoside metabolic process	GO:0042278	127	0.043	Yeast Worm
nucleoside metabolic process	GO:0009116	127	0.043	Yeast Worm
positive regulation of multicellular organismal process	GO:0051240	143	0.041
nucleoside monophosphate metabolic process	GO:0009123	52	0.041	Yeast Worm
nucleobase containing small molecule metabolic process	GO:0055086	174	0.041	Yeast Worm
endomembrane system organization	GO:0010256	119	0.040
ribonucleoside catabolic process	GO:0042454	112	0.040
protein complex biogenesis	GO:0070271	201	0.039
cell migration	GO:0016477	238	0.039
carboxylic acid metabolic process	GO:0019752	92	0.039
cellular nitrogen compound catabolic process	GO:0044270	165	0.038
feeding behavior	GO:0007631	50	0.038
spermatid differentiation	GO:0048515	114	0.037
muscle structure development	GO:0061061	224	0.036
cellular macromolecular complex assembly	GO:0034622	153	0.036
protein complex assembly	GO:0006461	200	0.035
cellular protein complex assembly	GO:0043623	71	0.034
development of primary sexual characteristics	GO:0045137	50	0.034	Worm
epithelial cell differentiation	GO:0030855	322	0.032
phosphorylation	GO:0016310	294	0.032	Yeast
regulation of developmental growth	GO:0048638	174	0.032
cellular catabolic process	GO:0044248	372	0.031
reproductive structure development	GO:0048608	74	0.031	Worm
columnar cuboidal epithelial cell differentiation	GO:0002065	256	0.031
developmental programmed cell death	GO:0010623	138	0.031
endocytosis	GO:0006897	310	0.030
negative regulation of cellular metabolic process	GO:0031324	382	0.030
ribonucleoside monophosphate metabolic process	GO:0009161	51	0.030	Yeast Worm
reproductive system development	GO:0061458	74	0.030	Worm
eye development	GO:0001654	323	0.029
organic substance catabolic process	GO:1901575	308	0.029
negative regulation of developmental process	GO:0051093	201	0.029
regulation of phosphate metabolic process	GO:0019220	210	0.028
maintenance of location	GO:0051235	73	0.028
regulation of protein metabolic process	GO:0051246	256	0.027
purine ribonucleoside monophosphate metabolic process	GO:0009167	50	0.027	Yeast Worm
catabolic process	GO:0009056	409	0.026
regulation of localization	GO:0032879	275	0.026
intracellular signal transduction	GO:0035556	300	0.026
positive regulation of cellular biosynthetic process	GO:0031328	316	0.026
intracellular transport	GO:0046907	228	0.025	Worm
regulation of cellular protein metabolic process	GO:0032268	243	0.025
regulation of growth	GO:0040008	233	0.025
nucleotide metabolic process	GO:0009117	161	0.024	Yeast Worm
purine nucleotide metabolic process	GO:0006163	146	0.024	Yeast Worm
negative regulation of cell differentiation	GO:0045596	143	0.023
regulation of proteolysis	GO:0030162	87	0.023
positive regulation of developmental process	GO:0051094	143	0.023
positive regulation of macromolecule metabolic process	GO:0010604	405	0.023
regulation of programmed cell death	GO:0043067	152	0.023
spermatid development	GO:0007286	98	0.023
mitochondrion organization	GO:0007005	65	0.023
male gamete generation	GO:0048232	201	0.023
ribonucleoside metabolic process	GO:0009119	127	0.023	Yeast Worm
generation of precursor metabolites and energy	GO:0006091	42	0.022	Yeast
positive regulation of growth	GO:0045927	75	0.021
sex differentiation	GO:0007548	81	0.021	Worm
regulation of neurogenesis	GO:0050767	158	0.021
vesicle mediated transport	GO:0016192	381	0.021
response to organic substance	GO:0010033	284	0.021
purine containing compound metabolic process	GO:0072521	155	0.021	Yeast Worm
response to endogenous stimulus	GO:0009719	119	0.021
organic substance transport	GO:0071702	257	0.021
carbohydrate derivative metabolic process	GO:1901135	217	0.020	Yeast Worm
apoptotic process	GO:0006915	159	0.020
purine nucleoside monophosphate metabolic process	GO:0009126	50	0.020	Yeast Worm
purine ribonucleotide metabolic process	GO:0009150	145	0.019	Yeast Worm
neuroblast proliferation	GO:0007405	74	0.019
regulation of molecular function	GO:0065009	217	0.019
regulation of cell proliferation	GO:0042127	163	0.018
nucleobase containing compound catabolic process	GO:0034655	165	0.018
ion transmembrane transport	GO:0034220	122	0.018	Worm
tricarboxylic acid metabolic process	GO:0072350	1	0.018
tube morphogenesis	GO:0035239	191	0.018
proteolysis	GO:0006508	192	0.018
purine ribonucleoside monophosphate catabolic process	GO:0009169	38	0.017
response to decreased oxygen levels	GO:0036293	58	0.017
positive regulation of viral process	GO:0048524	2	0.017
single organism intracellular transport	GO:1902582	207	0.017	Worm
purine ribonucleotide catabolic process	GO:0009154	109	0.017
chromosome organization	GO:0051276	360	0.017
purine ribonucleoside triphosphate metabolic process	GO:0009205	119	0.016	Yeast Worm
stem cell proliferation	GO:0072089	88	0.016
ribonucleotide catabolic process	GO:0009261	109	0.016
digestive tract development	GO:0048565	149	0.016
positive regulation of cell communication	GO:0010647	250	0.016
electron transport chain	GO:0022900	14	0.015	Yeast
nucleoside triphosphate catabolic process	GO:0009143	108	0.015
positive regulation of signaling	GO:0023056	243	0.015
organonitrogen compound catabolic process	GO:1901565	128	0.015
regulation of cell death	GO:0010941	173	0.015
response to oxygen levels	GO:0070482	59	0.015
positive regulation of catalytic activity	GO:0043085	118	0.015
nucleoside phosphate catabolic process	GO:1901292	110	0.014
epithelial cell development	GO:0002064	274	0.014
homeostatic process	GO:0042592	199	0.014
single organism biosynthetic process	GO:0044711	206	0.014	Worm
regionalization	GO:0003002	416	0.014
centrosome organization	GO:0051297	163	0.014
regulation of apoptotic process	GO:0042981	130	0.014
ribonucleoside triphosphate catabolic process	GO:0009203	108	0.014
protein modification process	GO:0036211	438	0.014
cellular component assembly involved in morphogenesis	GO:0010927	151	0.014
cation transport	GO:0006812	110	0.014	Worm
nad metabolic process	GO:0019674	1	0.014
exocrine system development	GO:0035272	162	0.013
negative regulation of growth	GO:0045926	84	0.013
developmental maturation	GO:0021700	172	0.013
regulation of cell cycle	GO:0051726	291	0.013
regulation of hydrolase activity	GO:0051336	97	0.013
organophosphate catabolic process	GO:0046434	112	0.013
circulatory system development	GO:0072359	82	0.013
regulation of catalytic activity	GO:0050790	185	0.013
activation of cysteine type endopeptidase activity	GO:0097202	17	0.013
carbohydrate derivative catabolic process	GO:1901136	118	0.013
digestive system development	GO:0055123	149	0.013
aromatic compound catabolic process	GO:0019439	166	0.013
regulation of phosphorus metabolic process	GO:0051174	210	0.013
positive regulation of hydrolase activity	GO:0051345	78	0.013
sensory organ morphogenesis	GO:0090596	260	0.013
response to abiotic stimulus	GO:0009628	341	0.012
negative regulation of nervous system development	GO:0051961	92	0.012
regulation of stem cell proliferation	GO:0072091	40	0.012
regulation of viral genome replication	GO:0045069	4	0.012
negative regulation of purine nucleotide catabolic process	GO:0033122	1	0.012
lipid storage	GO:0019915	38	0.012
positive regulation of molecular function	GO:0044093	136	0.012
purine containing compound catabolic process	GO:0072523	112	0.012
purine nucleoside catabolic process	GO:0006152	112	0.012
protein maturation	GO:0051604	71	0.012
glycosyl compound catabolic process	GO:1901658	112	0.012
immune response	GO:0006955	246	0.012
negative regulation of multicellular organismal process	GO:0051241	142	0.012
defense response	GO:0006952	300	0.011
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.011
negative regulation of neuroblast proliferation	GO:0007406	27	0.011
purine nucleoside triphosphate metabolic process	GO:0009144	119	0.011	Yeast Worm
regulation of phosphatase activity	GO:0010921	3	0.011
organelle inheritance	GO:0048308	2	0.011
purine ribonucleoside catabolic process	GO:0046130	112	0.011
metal ion homeostasis	GO:0055065	44	0.010
response to organic cyclic compound	GO:0014070	89	0.010
atp catabolic process	GO:0006200	38	0.010
organophosphate biosynthetic process	GO:0090407	46	0.010	Worm
ion transport	GO:0006811	145	0.010	Worm
response to hypoxia	GO:0001666	53	0.010
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.010
positive regulation of binding	GO:0051099	4	0.010
ribonucleoside triphosphate metabolic process	GO:0009199	119	0.010	Yeast Worm

CG4769 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of metabolism	DOID:0014667	0.045
musculoskeletal system disease	DOID:17	0.015
osteogenesis imperfecta	DOID:12347	0.015
connective tissue disease	DOID:65	0.015
disease of anatomical entity	DOID:7	0.015
bone disease	DOID:0080001	0.015
bone development disease	DOID:0080006	0.015
osteochondrodysplasia	DOID:2256	0.015
inherited metabolic disorder	DOID:655	0.011

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