Drosophila melanogaster

157 known processes

msps (Dmel_CG5000)

mini spindles

(Aliases: Dis1,Dmel\CG5000,MSPS,Msps,XMAP215,CG5000,TOG,anon-WO0140519.136)

msps biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
dna metabolic processGO:00062592270.962
developmental maturationGO:00217001720.945
sister chromatid segregationGO:0000819920.938
neuron projection guidanceGO:00974852410.911
axonogenesisGO:00074092900.903
establishment of localization in cellGO:00516494020.855
Worm
organic substance catabolic processGO:19015753080.813
mitotic sister chromatid segregationGO:0000070870.802
positive regulation of cellular component organizationGO:00511301560.799
growthGO:00400073590.792
cellular protein complex assemblyGO:0043623710.786
embryo development ending in birth or egg hatchingGO:00097921520.762
Worm
regulation of mitotic cell cycleGO:00073461900.760
mitotic nuclear divisionGO:00070672130.751
positive regulation of cellular catabolic processGO:0031331950.710
microtubule organizing center organizationGO:00310231680.706
Human
intracellular transportGO:00469072280.701
macromolecule catabolic processGO:00090571610.657
regulation of microtubule based processGO:0032886490.652
chemotaxisGO:00069352490.651
neurological system processGO:00508773580.643
macromolecular complex assemblyGO:00650032560.636
taxisGO:00423303040.574
regulation of cellular catabolic processGO:00313291570.567
regulation of localizationGO:00328792750.563
cellular catabolic processGO:00442483720.560
regulation of microtubule cytoskeleton organizationGO:0070507410.556
positive regulation of developmental processGO:00510941430.545
negative regulation of signalingGO:00230572190.533
regulation of cell shapeGO:00083601130.528
centrosome organizationGO:00512971630.522
Human
single organism cellular localizationGO:19025801800.505
negative regulation of signal transductionGO:00099682060.500
regulation of catabolic processGO:00098941700.499
organelle localizationGO:00516401480.499
Worm
cellular macromolecule localizationGO:00707272200.484
catabolic processGO:00090564090.473
single organism behaviorGO:00447083910.469
regulation of transferase activityGO:0051338580.463
chromosome organizationGO:00512763600.462
positive regulation of multicellular organismal processGO:00512401430.451
protein modification processGO:00362114380.435
vesicle mediated transportGO:00161923810.390
organelle assemblyGO:00709251980.387
cellular macromolecule catabolic processGO:00442651360.381
cellular macromolecular complex assemblyGO:00346221530.376
spindle organizationGO:00070512530.375
protein localizationGO:00081042840.365
negative regulation of cellular metabolic processGO:00313243820.357
nucleus localizationGO:0051647340.356
Worm
regulation of molecular functionGO:00650092170.356
meiotic cell cycle processGO:19030461320.353
Worm
negative regulation of response to stimulusGO:00485852580.348
regulation of cell cycleGO:00517262910.333
axon guidanceGO:00074112330.328
localization of cellGO:00516742570.325
dna repairGO:0006281540.316
regulation of cell cycle processGO:00105641810.309
regulation of organelle organizationGO:00330431960.308
regulation of cellular localizationGO:00603411360.291
chromosome segregationGO:00070591570.277
ubiquitin dependent protein catabolic processGO:0006511780.271
mitotic sister chromatid separationGO:0051306300.251
regulation of cell morphogenesisGO:00226041630.249
proteolysis involved in cellular protein catabolic processGO:0051603830.244
meiotic spindle organizationGO:0000212360.241
Worm
cell maturationGO:00484691440.241
modification dependent macromolecule catabolic processGO:0043632790.229
negative regulation of gene expressionGO:00106293870.221
protein targetingGO:0006605640.220
positive regulation of phosphate metabolic processGO:00459371390.220
cellular protein modification processGO:00064644380.217
mitotic spindle organizationGO:00070522200.216
heterocycle catabolic processGO:00467001660.198
regulation of protein metabolic processGO:00512462560.198
cellular response to chemical stimulusGO:00708871990.197
regulation of cellular component biogenesisGO:00440872010.196
oocyte developmentGO:00485991240.193
regulation of cell proliferationGO:00421271630.191
regulation of gene expression epigeneticGO:00400291280.188
regulation of cell developmentGO:00602842150.178
positive regulation of developmental growthGO:0048639620.178
positive regulation of nervous system developmentGO:0051962690.174
regulation of catalytic activityGO:00507901850.173
axon developmentGO:00615642970.171
negative regulation of cellular component organizationGO:00511291080.170
regulation of mitosisGO:0007088560.169
oocyte differentiationGO:00099941450.168
protein complex biogenesisGO:00702712010.161
endocytosisGO:00068973100.158
nucleoside triphosphate metabolic processGO:00091411200.154
positive regulation of cellular component biogenesisGO:0044089800.149
centrosome cycleGO:00070981370.149
dna conformation changeGO:00711031050.148
regulation of protein modification processGO:00313991120.145
regulation of cytoskeleton organizationGO:0051493890.144
regulation of phosphorus metabolic processGO:00511742100.142
spindle assemblyGO:0051225800.141
regulation of multicellular organismal developmentGO:20000264140.141
regulation of phosphate metabolic processGO:00192202100.139
positive regulation of transportGO:0051050920.139
cell migrationGO:00164772380.134
regulation of protein localizationGO:0032880760.134
regulation of transportGO:00510491810.133
cellular protein localizationGO:00346131600.131
positive regulation of organelle organizationGO:0010638650.131
phosphorylationGO:00163102940.130
organonitrogen compound metabolic processGO:19015643180.129
single organism catabolic processGO:00447122280.123
deathGO:00162652840.122
regulation of mitotic sister chromatid segregationGO:0033047280.119
negative regulation of cell communicationGO:00106482230.118
single organism intracellular transportGO:19025822070.118
regulation of cell cycle phase transitionGO:19019871300.117
negative regulation of protein complex disassemblyGO:0043242230.116
regulation of neuron deathGO:1901214260.116
organelle fissionGO:00482853400.113
embryonic development via the syncytial blastodermGO:00017001480.113
regulation of kinase activityGO:0043549530.112
regulation of mitotic cell cycle phase transitionGO:19019901300.111
positive regulation of nucleobase containing compound metabolic processGO:00459353320.110
mitotic cell cycle phase transitionGO:00447721380.107
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052240.107
developmental growthGO:00485892800.103
positive regulation of response to stimulusGO:00485843230.099
protein complex assemblyGO:00064612000.099
cellular protein catabolic processGO:0044257830.099
positive regulation of catalytic activityGO:00430851180.098
intracellular protein transportGO:00068861040.097
regulation of cell divisionGO:0051302720.096
nucleobase containing compound catabolic processGO:00346551650.096
aromatic compound catabolic processGO:00194391660.095
regulation of nuclear divisionGO:0051783580.091
cellular response to dna damage stimulusGO:00069742230.088
regulation of mitotic sister chromatid separationGO:0010965280.087
positive regulation of protein modification processGO:0031401580.086
positive regulation of signal transductionGO:00099672230.086
positive regulation of catabolic processGO:00098961050.085
proteolysisGO:00065081920.085
regulation of phosphorylationGO:00423251470.084
apoptotic processGO:00069151590.083
positive regulation of gene expressionGO:00106282900.083
response to abiotic stimulusGO:00096283410.083
response to hypoxiaGO:0001666530.082
positive regulation of signalingGO:00230562430.080
protein localization to organelleGO:0033365820.079
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.076
purine nucleotide catabolic processGO:00061951090.076
nuclear divisionGO:00002803320.074
cytoplasmic transportGO:00164821300.074
organic substance transportGO:00717022570.073
regulation of cellular protein metabolic processGO:00322682430.072
regulation of establishment of protein localizationGO:0070201610.072
modification dependent protein catabolic processGO:0019941780.071
positive regulation of macromolecule metabolic processGO:00106044050.071
positive regulation of growthGO:0045927750.071
positive regulation of phosphorus metabolic processGO:00105621390.070
regulation of protein phosphorylationGO:0001932640.070
small gtpase mediated signal transductionGO:0007264880.069
protein catabolic processGO:00301631010.069
positive regulation of phosphorylationGO:0042327870.068
adult behaviorGO:00305341370.068
negative regulation of cellular protein metabolic processGO:0032269850.067
regulation of purine nucleotide catabolic processGO:0033121480.067
determination of adult lifespanGO:00083401370.065
negative regulation of phosphorus metabolic processGO:0010563450.065
positive regulation of nitrogen compound metabolic processGO:00511733540.064
mitotic cell cycle embryonicGO:0045448380.063
regulation of intracellular transportGO:0032386640.062
positive regulation of rna metabolic processGO:00512542710.062
cell deathGO:00082192790.061
positive regulation of hydrolase activityGO:0051345780.061
protein phosphorylationGO:00064681690.060
purine ribonucleoside triphosphate metabolic processGO:00092051190.059
cellular nitrogen compound catabolic processGO:00442701650.059
membrane organizationGO:00610241120.057
positive regulation of nucleic acid templated transcriptionGO:19035082660.057
regulation of protein targetingGO:1903533290.057
positive regulation of cell developmentGO:0010720610.057
regulation of mitotic metaphase anaphase transitionGO:0030071260.057
protein modification by small protein conjugation or removalGO:00706471060.056
regulation of nucleotide catabolic processGO:0030811480.055
ribonucleoside triphosphate catabolic processGO:00092031080.055
positive regulation of rna biosynthetic processGO:19026802660.054
negative regulation of gene expression epigeneticGO:0045814770.054
mitotic spindle elongationGO:0000022810.053
cellular response to organic substanceGO:00713101320.052
regulation of nervous system developmentGO:00519602480.051
regulation of axonogenesisGO:0050770320.051
regulation of nucleoside metabolic processGO:0009118500.050
nucleus organizationGO:0006997450.050
regulation of chromosome segregationGO:0051983320.050
ribonucleotide catabolic processGO:00092611090.049
regulation of ras protein signal transductionGO:0046578930.049
multicellular organismal reproductive behaviorGO:00330571100.049
Worm
cellular amino acid metabolic processGO:0006520610.049
organic cyclic compound catabolic processGO:19013611680.048
purine ribonucleoside metabolic processGO:00461281270.047
regulation of hydrolase activityGO:0051336970.045
regulation of protein localization to nucleusGO:1900180290.045
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic processGO:0031145300.045
cell growthGO:00160491080.044
metaphase anaphase transition of mitotic cell cycleGO:0007091280.043
eye developmentGO:00016543230.042
brain developmentGO:00074201200.042
sensory organ morphogenesisGO:00905962600.042
gene silencingGO:00164581380.042
regulation of protein transportGO:0051223570.041
sex differentiationGO:0007548810.041
Worm
locomotory behaviorGO:00076261760.041
negative regulation of phosphate metabolic processGO:0045936450.041
ribonucleoside monophosphate catabolic processGO:0009158390.040
maintenance of protein location in cellGO:0032507260.040
regulation of cytoplasmic transportGO:1903649470.040
phenol containing compound metabolic processGO:0018958570.039
protein transportGO:00150311550.039
establishment of protein localization to organelleGO:0072594620.039
regulation of vesicle mediated transportGO:0060627590.039
organophosphate metabolic processGO:00196371950.039
nucleoside catabolic processGO:00091641120.039
agingGO:00075681430.038
regulation of wnt signaling pathwayGO:0030111680.038
single organism membrane organizationGO:0044802930.038
negative regulation of mitotic cell cycle phase transitionGO:19019911030.038
response to organic substanceGO:00100332840.037
regulation of intracellular signal transductionGO:19025312360.037
adult locomotory behaviorGO:0008344760.036
negative regulation of phosphorylationGO:0042326350.036
microtubule based movementGO:0007018510.036
regulation of small gtpase mediated signal transductionGO:0051056930.036
ras protein signal transductionGO:0007265880.036
purine nucleotide metabolic processGO:00061631460.036
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161540.036
cell divisionGO:00513012480.036
Worm
oocyte axis specificationGO:00073091080.035
protein ubiquitinationGO:0016567700.035
negative regulation of organelle organizationGO:0010639560.035
negative regulation of intrinsic apoptotic signaling pathwayGO:200124310.034
cognitionGO:00508901410.034
regulation of cell sizeGO:0008361630.034
purine ribonucleotide catabolic processGO:00091541090.034
protein localization to nucleusGO:0034504550.034
nucleotide catabolic processGO:00091661090.034
cell fate determinationGO:0001709910.033
negative regulation of molecular functionGO:0044092510.033
response to lipopolysaccharideGO:003249640.033
protein polymerizationGO:0051258420.033
purine ribonucleoside triphosphate catabolic processGO:00092071080.033
positive regulation of protein metabolic processGO:00512471280.032
pseudocleavage involved in syncytial blastoderm formationGO:003058990.032
actin cytoskeleton organizationGO:00300362060.032
positive regulation of cell communicationGO:00106472500.032
small molecule metabolic processGO:00442813050.032
mitochondrion distributionGO:0048311100.032
regulation of nucleocytoplasmic transportGO:0046822350.031
regulation of cellular protein catabolic processGO:1903362440.031
nuclear migrationGO:0007097200.031
Worm
intracellular signal transductionGO:00355563000.031
regulation of metaphase anaphase transition of cell cycleGO:1902099260.031
photoreceptor cell differentiationGO:00465301700.030
organophosphate catabolic processGO:00464341120.030
glycosyl compound metabolic processGO:19016571270.030
purine nucleoside triphosphate metabolic processGO:00091441190.030
glycosyl compound catabolic processGO:19016581120.029
nucleocytoplasmic transportGO:0006913720.029
positive regulation of neuron differentiationGO:0045666260.029
macromolecular complex disassemblyGO:0032984370.029
regulation of synapse structure and activityGO:00508031280.029
positive regulation of molecular functionGO:00440931360.028
cytokinesisGO:0000910900.028
wnt signaling pathwayGO:0016055980.028
eye morphogenesisGO:00485922600.028
negative regulation of cell differentiationGO:00455961430.027
positive regulation of transcription dna templatedGO:00458932660.027
nuclear importGO:0051170510.027
body morphogenesisGO:001017120.027
Worm
negative regulation of developmental processGO:00510932010.027
microtubule polymerization or depolymerizationGO:0031109390.027
cell proliferationGO:00082832990.027
cellular amine metabolic processGO:0044106120.027
negative regulation of necrotic cell deathGO:006054710.027
positive regulation of chromatin silencing at telomereGO:003194020.027
reproductive system developmentGO:0061458740.027
Worm
ribose phosphate metabolic processGO:00196931450.026
oocyte constructionGO:00073081120.026
regulation of nucleotide metabolic processGO:0006140620.026
gliogenesisGO:0042063800.026
regulation of mrna 3 end processingGO:003144070.025
positive regulation of purine nucleotide metabolic processGO:1900544550.025
oxoacid metabolic processGO:00434361030.025
regulation of response to stressGO:00801342000.025
positive regulation of macromolecule biosynthetic processGO:00105572830.024
regulation of hemocyte proliferationGO:0035206370.024
positive regulation of nucleotide metabolic processGO:0045981550.024
establishment of organelle localizationGO:00516561220.024
Worm
metaphase anaphase transition of cell cycleGO:0044784280.024
regulation of immune system processGO:00026821760.024
actin filament based processGO:00300292200.023
anterior posterior pattern specificationGO:00099521360.023
regulation of reproductive processGO:2000241540.023
positive regulation of gtp catabolic processGO:0033126430.023
photoreceptor cell developmentGO:0042461960.023
programmed cell deathGO:00125012570.023
enzyme linked receptor protein signaling pathwayGO:00071671790.023
purine ribonucleotide metabolic processGO:00091501450.023
signal transduction by phosphorylationGO:00230141070.023
regulation of intracellular protein transportGO:0033157460.023
regulation of growthGO:00400082330.023
negative regulation of rna metabolic processGO:00512532510.023
negative regulation of microtubule polymerization or depolymerizationGO:0031111210.023
sensory perceptionGO:00076001960.023
positive regulation of cell differentiationGO:0045597640.022
phagocytosisGO:00069092150.022
negative regulation of cytoskeleton organizationGO:0051494300.022
regulation of protein kinase activityGO:0045859510.022
negative regulation of nucleobase containing compound metabolic processGO:00459342610.022
negative regulation of protein metabolic processGO:0051248850.022
microtubule cytoskeleton organization involved in mitosisGO:1902850520.022
negative regulation of macromolecule biosynthetic processGO:00105582700.021
regulation of cellular amine metabolic processGO:003323830.021
telencephalon developmentGO:002153720.021
regulation of cellular component movementGO:0051270420.021
positive regulation of nucleotide catabolic processGO:0030813460.021
positive regulation of cellular biosynthetic processGO:00313283160.020
purine nucleoside triphosphate catabolic processGO:00091461080.020
amine metabolic processGO:0009308120.020
positive regulation of cell cycle g2 m phase transitionGO:190275120.020
regulation of multi organism processGO:00439001310.020
organic acid metabolic processGO:00060821030.020
atp metabolic processGO:0046034490.020
endosomal transportGO:0016197440.020
nucleotide metabolic processGO:00091171610.019
response to oxygen containing compoundGO:19017002000.019
molting cycleGO:0042303560.019
positive regulation of intracellular transportGO:0032388420.019
ribonucleoside triphosphate metabolic processGO:00091991190.019
multicellular organismal agingGO:00102591400.019
regulation of protein catabolic processGO:0042176550.019
spermatogenesisGO:00072832000.019
positive regulation of cellular protein metabolic processGO:00322701180.018
proteasomal protein catabolic processGO:0010498590.018
carbohydrate derivative catabolic processGO:19011361180.018
regulation of protein complex assemblyGO:0043254420.018
developmental cell growthGO:0048588520.018
protein import into nucleusGO:0006606510.018
cellular component disassemblyGO:0022411460.017
negative regulation of epithelial cell proliferationGO:005068040.017
hindbrain developmentGO:003090220.017
pronuclear migrationGO:003504640.017
Worm
epithelial cell developmentGO:00020642740.017
regulation of cellular ketone metabolic processGO:001056530.017
innate immune responseGO:00450871440.017
positive regulation of mapk cascadeGO:0043410630.017
cellular ketone metabolic processGO:0042180240.017
positive regulation of neurogenesisGO:0050769410.017
regulation of mapk cascadeGO:0043408920.016
actin filament organizationGO:00070151260.016
nucleobase containing small molecule metabolic processGO:00550861740.016
spindle assembly involved in mitosisGO:0090307500.016
response to light stimulusGO:00094161240.016
gland morphogenesisGO:00226121450.016
purine containing compound catabolic processGO:00725231120.015
mrna 3 end processingGO:0031124280.015
regulation of endocytosisGO:0030100370.015
cardiovascular system developmentGO:0072358820.015
mitochondrial membrane organizationGO:000700630.015
ribonucleoside metabolic processGO:00091191270.015
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.014
regulation of protein import into nucleusGO:0042306280.014
single organism biosynthetic processGO:00447112060.014
immune system processGO:00023763470.014
negative regulation of mitotic cell cycleGO:00459301090.014
positive regulation of cellular amine metabolic processGO:003324000.014
cell adhesionGO:00071551360.014
negative regulation of multicellular organismal processGO:00512411420.014
negative regulation of catalytic activityGO:0043086420.014
chromosome condensationGO:0030261410.014
positive regulation of proteolysisGO:0045862520.014
purine ribonucleoside catabolic processGO:00461301120.014
regulation of cell differentiationGO:00455953020.014
negative regulation of mitotic sister chromatid segregationGO:0033048130.014
nucleoside metabolic processGO:00091161270.014
regulation of apoptotic processGO:00429811300.014
negative regulation of cell developmentGO:0010721620.014
regulation of chromosome organizationGO:0033044640.014
protein modification by small protein conjugationGO:0032446790.014
regulation of cellular response to stressGO:0080135890.014
erk1 and erk2 cascadeGO:0070371390.014
negative regulation of protein depolymerizationGO:1901880230.014
digestive system developmentGO:00551231490.013
negative regulation of nervous system developmentGO:0051961920.013
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.013
glial cell differentiationGO:0010001350.013
regulation of dna metabolic processGO:0051052340.013
dna packagingGO:0006323910.013
positive regulation of cdc42 gtpase activityGO:004308920.013
negative regulation of biosynthetic processGO:00098902770.013
purine nucleoside metabolic processGO:00422781270.013
chromatin silencingGO:0006342760.013
maintenance of location in cellGO:0051651280.013
head developmentGO:00603221350.013
epithelial cell differentiationGO:00308553220.012
dna replicationGO:0006260480.012
carbohydrate derivative metabolic processGO:19011352170.012
positive regulation of kinase activityGO:0033674250.012
digestive tract developmentGO:00485651490.012
regulation of protein serine threonine kinase activityGO:0071900250.012
reproductive structure developmentGO:0048608740.012
Worm
organ growthGO:0035265560.012
regulation of multicellular organism growthGO:0040014400.012
immune response regulating signaling pathwayGO:000276420.012
lipid metabolic processGO:00066291210.012
nucleoside phosphate catabolic processGO:19012921100.012
detection of stimulusGO:00516061560.012
establishment of nucleus localizationGO:0040023260.012
Worm
regulation of gene silencingGO:0060968630.012
reactive oxygen species biosynthetic processGO:190340900.011
response to oxygen levelsGO:0070482590.011
phospholipid metabolic processGO:0006644230.011
histone h3 k9 modificationGO:0061647120.011
positive regulation of cell proliferationGO:0008284470.011
purine nucleoside monophosphate metabolic processGO:0009126500.011
positive regulation of bindingGO:005109940.011
hematopoietic stem cell differentiationGO:006021810.011
forebrain developmentGO:003090020.011
eye antennal disc developmentGO:0035214600.011
gene silencing by rnaGO:0031047570.011
stress granule disassemblyGO:003561710.011
immune responseGO:00069552460.011
cellular response to endogenous stimulusGO:0071495800.011
tripartite regional subdivisionGO:00073511030.011
multi multicellular organism processGO:00447061230.011
Worm
neuron migrationGO:000176450.011
compound eye morphogenesisGO:00017452490.011
neuron recognitionGO:00080381010.011
response to lipidGO:0033993380.010
positive regulation of endocytosisGO:0045807220.010
cell projection assemblyGO:0030031940.010
nucleoside monophosphate catabolic processGO:0009125390.010
positive regulation of multicellular organism growthGO:0040018210.010
regulation of proteolysis involved in cellular protein catabolic processGO:1903050440.010
positive regulation of protein transportGO:0051222370.010
nucleoside triphosphate catabolic processGO:00091431080.010
kinetochore organizationGO:005138390.010
developmental programmed cell deathGO:00106231380.010

msps disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.158
organ system cancerDOID:005068600.036
disease of cellular proliferationDOID:1456600.036
cancerDOID:16200.036
nervous system diseaseDOID:86300.027