Drosophila melanogaster

95 known processes

Pcl (Dmel_CG5109)

Polycomblike

(Aliases: Dmel\CG5109,CG5109,pcl,l(2)s1859,PCL)

Pcl biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
negative regulation of transcription dna templatedGO:00458922370.999
negative regulation of nucleobase containing compound metabolic processGO:00459342610.999
negative regulation of macromolecule biosynthetic processGO:00105582700.999
negative regulation of nucleic acid templated transcriptionGO:19035072400.998
negative regulation of cellular biosynthetic processGO:00313272770.997
gene silencingGO:00164581380.988
imaginal disc derived appendage developmentGO:00487373990.979
negative regulation of gene expressionGO:00106293870.976
imaginal disc derived appendage morphogenesisGO:00351143950.958
regulation of transcription from rna polymerase ii promoterGO:00063573780.949
Mouse
wing disc morphogenesisGO:00074723440.943
appendage morphogenesisGO:00351073970.936
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.935
regionalizationGO:00030024160.902
Mouse
negative regulation of rna biosynthetic processGO:19026792400.900
negative regulation of biosynthetic processGO:00098902770.896
negative regulation of rna metabolic processGO:00512532510.891
negative regulation of nitrogen compound metabolic processGO:00511722650.881
imaginal disc derived wing morphogenesisGO:00074763370.881
negative regulation of cellular metabolic processGO:00313243820.852
defense response to fungusGO:0050832480.845
chromatin silencingGO:0006342760.692
imaginal disc derived leg morphogenesisGO:0007480800.690
regulation of gene expression epigeneticGO:00400291280.666
trunk segmentationGO:003529080.658
response to fungusGO:0009620500.647
chromatin organizationGO:00063252070.619
appendage developmentGO:00487364010.608
leg disc developmentGO:0035218920.600
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.598
Mouse
chromatin modificationGO:00165681470.583
specification of segmental identity trunkGO:003529270.533
segmentationGO:00352822070.532
Mouse
covalent chromatin modificationGO:00165691060.526
Human Mouse
imaginal disc pattern formationGO:0007447910.457
positive regulation of macromolecule biosynthetic processGO:00105572830.447
Mouse
tissue morphogenesisGO:00487292970.406
segment specificationGO:0007379330.403
Mouse
post embryonic appendage morphogenesisGO:00351203850.364
chromatin mediated maintenance of transcriptionGO:004809670.347
transcription from rna polymerase ii promoterGO:00063663680.329
Mouse
neuroblast differentiationGO:0014016290.323
positive regulation of rna metabolic processGO:00512542710.303
Mouse
ectodermal placode morphogenesisGO:007169740.284
regulation of cell shapeGO:00083601130.263
regulation of dna templated transcription elongationGO:0032784170.257
regulation of response to gamma radiationGO:200122840.252
positive regulation of macromolecule metabolic processGO:00106044050.176
Human Mouse
enzyme linked receptor protein signaling pathwayGO:00071671790.174
dorsal ventral pattern formation imaginal discGO:0007450510.174
protein modification processGO:00362114380.172
Human Mouse
epithelial cell differentiationGO:00308553220.166
wnt signaling pathwayGO:0016055980.161
nephron developmentGO:007200630.157
negative regulation of gene expression epigeneticGO:0045814770.145
chemosensory behaviorGO:00076351060.129
embryonic morphogenesisGO:00485982060.122
carbohydrate derivative metabolic processGO:19011352170.120
histone modificationGO:00165701060.118
Human Mouse
histone lysine methylationGO:0034968320.117
Human Mouse
leg disc morphogenesisGO:0007478800.117
imaginal disc derived wing margin morphogenesisGO:0008587410.108
chromosome organizationGO:00512763600.107
eye antennal disc developmentGO:0035214600.107
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.103
Mouse
reproductive structure developmentGO:0048608740.102
peptidyl lysine modificationGO:0018205570.096
histone h3 k4 methylationGO:0051568160.095
sex differentiationGO:0007548810.094
organelle fissionGO:00482853400.093
vesicle mediated transportGO:00161923810.084
regulation of molecular functionGO:00650092170.082
salivary gland cell autophagic cell deathGO:0035071830.081
methylationGO:0032259470.079
Human Mouse
morphogenesis of an epitheliumGO:00020092760.079
zygotic determination of anterior posterior axis embryoGO:0007354270.079
compound eye developmentGO:00487493070.078
tissue deathGO:00162711020.074
regulation of multicellular organism growthGO:0040014400.073
positive regulation of phosphorus metabolic processGO:00105621390.072
spermatogenesisGO:00072832000.068
dendrite developmentGO:00163582040.068
ectodermal placode developmentGO:007169640.066
positive regulation of nucleic acid templated transcriptionGO:19035082660.064
Mouse
sex determinationGO:0007530180.064
phagocytosisGO:00069092150.062
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.061
positive regulation of biosynthetic processGO:00098913160.060
Mouse
sensory perceptionGO:00076001960.057
apposition of dorsal and ventral imaginal disc derived wing surfacesGO:0007475150.054
germarium derived female germ line cyst encapsulationGO:003070880.053
body morphogenesisGO:001017120.052
regulation of phosphorus metabolic processGO:00511742100.051
embryonic pattern specificationGO:00098801740.050
neurological system processGO:00508773580.047
imaginal disc derived wing vein specificationGO:0007474480.047
circadian behaviorGO:0048512760.046
ectodermal placode formationGO:006078840.046
histone methylationGO:0016571400.045
Human Mouse
endocytosisGO:00068973100.045
dendrite morphogenesisGO:00488131990.045
salivary gland histolysisGO:0035070880.044
nucleosome positioningGO:001658430.043
reproductive system developmentGO:0061458740.043
germ line cyst encapsulationGO:004813880.043
eye photoreceptor cell differentiationGO:00017541450.042
regulation of chromosome organizationGO:0033044640.042
Human Mouse
protein dna complex subunit organizationGO:0071824860.042
cellular protein modification processGO:00064644380.041
Human Mouse
wing disc pattern formationGO:0035222660.040
regulation of meiosisGO:004002030.039
male gamete generationGO:00482322010.038
single organism behaviorGO:00447083910.036
stem cell developmentGO:0048864790.036
Mouse
mesodermal cell fate specificationGO:000750120.035
central nervous system developmentGO:00074172010.035
response to ecdysoneGO:0035075340.034
carbohydrate metabolic processGO:0005975820.034
protein alkylationGO:0008213430.033
Human Mouse
organonitrogen compound metabolic processGO:19015643180.033
histone ubiquitinationGO:001657440.032
nephron epithelium developmentGO:007200930.032
secretionGO:00469031090.032
chromatin remodelingGO:0006338720.031
regulation of phosphate metabolic processGO:00192202100.031
dorsal ventral pattern formationGO:00099531330.031
protein acetylationGO:0006473390.030
positive regulation of cell communicationGO:00106472500.029
wing disc dorsal ventral pattern formationGO:0048190470.029
response to ketoneGO:1901654340.029
imaginal disc derived wing vein morphogenesisGO:0008586440.029
intestinal epithelial structure maintenanceGO:006072930.029
secretion by cellGO:00329401010.028
regulation of chromatin silencingGO:0031935360.028
single organism carbohydrate metabolic processGO:0044723720.028
protein methylationGO:0006479430.027
Human Mouse
neuron recognitionGO:00080381010.027
neuroblast fate determinationGO:0007400120.027
regulation of catalytic activityGO:00507901850.027
macromolecule methylationGO:0043414450.027
Human Mouse
mating behaviorGO:00076171060.027
response to sterolGO:0036314340.026
hindbrain developmentGO:003090220.026
organophosphate metabolic processGO:00196371950.026
positive regulation of signalingGO:00230562430.025
positive regulation of nitrogen compound metabolic processGO:00511733540.025
Mouse
female germ line cyst encapsulationGO:004813980.025
negative regulation of cell communicationGO:00106482230.024
maintenance of gastrointestinal epitheliumGO:003027730.024
limb morphogenesisGO:003510810.024
response to biotic stimulusGO:00096072940.023
eye developmentGO:00016543230.023
wound healing spreading of epidermal cellsGO:003531310.023
regulation of histone modificationGO:0031056200.022
Human Mouse
gastrulationGO:0007369700.022
regulation of protein metabolic processGO:00512462560.022
Human Mouse
synaptic target recognitionGO:0008039450.022
compound eye photoreceptor cell differentiationGO:00017511400.022
histone acetylationGO:0016573380.022
brain developmentGO:00074201200.022
developmental programmed cell deathGO:00106231380.022
nucleosome organizationGO:0034728590.022
dna damage checkpointGO:0000077780.022
anterior posterior pattern specificationGO:00099521360.021
compound eye morphogenesisGO:00017452490.021
positive regulation of nucleobase containing compound metabolic processGO:00459353320.021
Mouse
autophagic cell deathGO:0048102830.020
gonad developmentGO:0008406500.020
signal transduction by phosphorylationGO:00230141070.020
regulation of protein modification processGO:00313991120.020
Human Mouse
negative regulation of signal transductionGO:00099682060.019
multi organism reproductive behaviorGO:00447051210.019
paracrine signalingGO:003800170.019
gene silencing by rnaGO:0031047570.019
glycoprotein metabolic processGO:0009100410.019
columnar cuboidal epithelial cell developmentGO:00020662490.019
meiotic cell cycleGO:00513211710.019
blastoderm segmentationGO:00073501590.019
programmed cell deathGO:00125012570.019
skin developmentGO:0043588650.018
regulation of epithelial cell differentiationGO:003085640.018
dna integrity checkpointGO:0031570810.018
neuroblast fate commitmentGO:0014017190.018
response to external biotic stimulusGO:00432072930.017
muscle structure developmentGO:00610612240.017
positive regulation of response to stimulusGO:00485843230.017
epithelial tube morphogenesisGO:0060562880.016
locomotory behaviorGO:00076261760.016
development of primary sexual characteristicsGO:0045137500.016
cardioblast cell fate commitmentGO:0042684140.016
cellular response to endogenous stimulusGO:0071495800.016
open tracheal system developmentGO:00074242040.016
convergent extensionGO:006002620.015
homeostatic processGO:00425921990.015
small molecule metabolic processGO:00442813050.015
transmembrane transportGO:00550851390.015
carbohydrate derivative biosynthetic processGO:1901137850.015
response to superoxideGO:000030330.015
positive regulation of cellular protein metabolic processGO:00322701180.015
Human Mouse
regulation of cell cycleGO:00517262910.015
cell recognitionGO:00080371020.015
positive regulation of gene expressionGO:00106282900.015
Mouse
neuroblast developmentGO:0014019130.014
positive regulation of catalytic activityGO:00430851180.014
gland developmentGO:00487321910.014
nuclear divisionGO:00002803320.014
ecdysone mediated induction of salivary gland cell autophagic cell deathGO:0035072120.014
purine ribonucleotide catabolic processGO:00091541090.014
matingGO:00076181200.014
olfactory behaviorGO:0042048970.014
internal protein amino acid acetylationGO:0006475380.014
ion transportGO:00068111450.013
ovarian follicle cell stalk formationGO:0030713170.013
sensory organ morphogenesisGO:00905962600.013
optic placode formationGO:000174340.013
nucleoside phosphate catabolic processGO:19012921100.013
mapk cascadeGO:00001651070.013
dna alkylationGO:000630540.013
regulation of decapentaplegic signaling pathwayGO:009009780.013
morphogenesis of follicular epitheliumGO:0016333360.013
hematopoietic or lymphoid organ developmentGO:0048534570.013
embryonic development via the syncytial blastodermGO:00017001480.013
fertilizationGO:0009566260.012
organelle assemblyGO:00709251980.012
embryonic organ developmentGO:0048568500.012
negative regulation of response to gamma radiationGO:200122940.012
tube morphogenesisGO:00352391910.012
regulation of tube sizeGO:0035150460.012
renal tubule developmentGO:0061326640.012
pigmentationGO:0043473750.012
long chain fatty acid metabolic processGO:000167630.012
defense responseGO:00069523000.012
anterior head developmentGO:009706530.012
regulation of epidermal growth factor receptor signaling pathwayGO:0042058420.012
regulation of organelle organizationGO:00330431960.011
Human Mouse
interspecies interaction between organismsGO:0044419160.011
positive regulation of rna biosynthetic processGO:19026802660.011
Mouse
ribonucleotide catabolic processGO:00092611090.011
protein glycosylationGO:0006486320.011
histolysisGO:00075591020.011
negative regulation of response to stimulusGO:00485852580.011
wound healingGO:0042060750.011
positive regulation of gene expression epigeneticGO:0045815160.011
protein dna complex assemblyGO:0065004630.011
larval developmentGO:00021641040.011
multicellular organism growthGO:0035264460.011
purine ribonucleotide metabolic processGO:00091501450.011
positive regulation of cellular biosynthetic processGO:00313283160.011
Mouse
tube developmentGO:00352952440.011
mitotic nuclear divisionGO:00070672130.011
positive regulation of phosphorylationGO:0042327870.011
camera type eye morphogenesisGO:004859320.011
kidney developmentGO:000182230.011
response to organic substanceGO:00100332840.011
myofibril assemblyGO:0030239360.010
imaginal disc derived female genitalia developmentGO:000748660.010
positive regulation of transcription dna templatedGO:00458932660.010
Mouse
negative regulation of cellular protein metabolic processGO:0032269850.010
Mouse

Pcl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
cancerDOID:16200.024
organ system cancerDOID:005068600.024
disease of cellular proliferationDOID:1456600.024
nervous system diseaseDOID:86300.011
disease of anatomical entityDOID:700.011