| protein modification by small protein conjugation or removal | GO:0070647 | 106 | 0.733 | Human Mouse |
| synapse organization | GO:0050808 | 196 | 0.693 | |
| cellular protein modification process | GO:0006464 | 438 | 0.663 | Human Mouse |
| chromatin organization | GO:0006325 | 207 | 0.540 | |
| dna metabolic process | GO:0006259 | 227 | 0.504 | Human Mouse |
| protein modification by small protein conjugation | GO:0032446 | 79 | 0.479 | Human Mouse |
| protein ubiquitination | GO:0016567 | 70 | 0.424 | Human Mouse |
| chromosome organization | GO:0051276 | 360 | 0.396 | |
| photoreceptor cell differentiation | GO:0046530 | 170 | 0.385 | |
| regulation of cell death | GO:0010941 | 173 | 0.335 | Human |
| regulation of catalytic activity | GO:0050790 | 185 | 0.310 | |
| protein acetylation | GO:0006473 | 39 | 0.299 | |
| protein modification process | GO:0036211 | 438 | 0.298 | Human Mouse |
| transcription from rna polymerase ii promoter | GO:0006366 | 368 | 0.284 | Zebrafish Mouse |
| regulation of gene expression epigenetic | GO:0040029 | 128 | 0.282 | Mouse |
| internal peptidyl lysine acetylation | GO:0018393 | 38 | 0.262 | |
| gene silencing | GO:0016458 | 138 | 0.248 | |
| positive regulation of macromolecule metabolic process | GO:0010604 | 405 | 0.245 | Human Mouse |
| regulation of protein metabolic process | GO:0051246 | 256 | 0.241 | |
| appendage morphogenesis | GO:0035107 | 397 | 0.225 | |
| carbohydrate derivative metabolic process | GO:1901135 | 217 | 0.221 | |
| nucleocytoplasmic transport | GO:0006913 | 72 | 0.199 | Human |
| trachea development | GO:0060438 | 29 | 0.198 | |
| post embryonic appendage morphogenesis | GO:0035120 | 385 | 0.193 | |
| taxis | GO:0042330 | 304 | 0.189 | |
| imaginal disc derived appendage development | GO:0048737 | 399 | 0.188 | |
| negative regulation of cell communication | GO:0010648 | 223 | 0.185 | Human |
| positive regulation of endopeptidase activity | GO:0010950 | 26 | 0.183 | |
| growth | GO:0040007 | 359 | 0.170 | Mouse |
| regulation of molecular function | GO:0065009 | 217 | 0.167 | |
| negative regulation of gene expression | GO:0010629 | 387 | 0.167 | Human Mouse |
| intracellular transport | GO:0046907 | 228 | 0.155 | Human |
| regulation of cell cycle process | GO:0010564 | 181 | 0.148 | |
| imaginal disc derived appendage morphogenesis | GO:0035114 | 395 | 0.134 | |
| chromatin remodeling | GO:0006338 | 72 | 0.133 | |
| chromatin modification | GO:0016568 | 147 | 0.130 | |
| protein acylation | GO:0043543 | 42 | 0.125 | |
| regulation of synapse organization | GO:0050807 | 110 | 0.119 | |
| positive regulation of nitrogen compound metabolic process | GO:0051173 | 354 | 0.117 | Human Mouse |
| larval midgut histolysis | GO:0035069 | 22 | 0.117 | |
| peptidyl lysine modification | GO:0018205 | 57 | 0.114 | |
| positive regulation of cellular biosynthetic process | GO:0031328 | 316 | 0.114 | Mouse |
| extracellular structure organization | GO:0043062 | 46 | 0.112 | |
| purine nucleotide metabolic process | GO:0006163 | 146 | 0.106 | |
| positive regulation of catalytic activity | GO:0043085 | 118 | 0.104 | |
| positive regulation of transcription from rna polymerase ii promoter | GO:0045944 | 204 | 0.104 | |
| nuclear division | GO:0000280 | 332 | 0.097 | |
| eye development | GO:0001654 | 323 | 0.097 | |
| catabolic process | GO:0009056 | 409 | 0.095 | Human Mouse |
| negative regulation of response to stimulus | GO:0048585 | 258 | 0.095 | Human |
| positive regulation of proteolysis | GO:0045862 | 52 | 0.092 | |
| protein catabolic process | GO:0030163 | 101 | 0.091 | Human Mouse |
| positive regulation of molecular function | GO:0044093 | 136 | 0.090 | |
| extracellular matrix organization | GO:0030198 | 32 | 0.089 | |
| compound eye photoreceptor cell differentiation | GO:0001751 | 140 | 0.088 | |
| cardiovascular system development | GO:0072358 | 82 | 0.087 | |
| regulation of mitotic cell cycle | GO:0007346 | 190 | 0.084 | |
| regionalization | GO:0003002 | 416 | 0.084 | |
| eye morphogenesis | GO:0048592 | 260 | 0.084 | |
| histone acetylation | GO:0016573 | 38 | 0.077 | |
| endocytosis | GO:0006897 | 310 | 0.077 | |
| negative regulation of programmed cell death | GO:0043069 | 72 | 0.075 | |
| chromatin silencing | GO:0006342 | 76 | 0.074 | |
| organelle localization | GO:0051640 | 148 | 0.072 | |
| regulation of gene silencing | GO:0060968 | 63 | 0.072 | |
| cellular catabolic process | GO:0044248 | 372 | 0.071 | |
| positive regulation of nucleobase containing compound metabolic process | GO:0045935 | 332 | 0.070 | Human Mouse |
| tissue death | GO:0016271 | 102 | 0.069 | |
| eggshell formation | GO:0030703 | 105 | 0.068 | |
| negative regulation of signaling | GO:0023057 | 219 | 0.065 | Human |
| dendrite morphogenesis | GO:0048813 | 199 | 0.065 | |
| negative regulation of nucleobase containing compound metabolic process | GO:0045934 | 261 | 0.065 | Human Mouse |
| columnar cuboidal epithelial cell development | GO:0002066 | 249 | 0.064 | |
| proteolysis | GO:0006508 | 192 | 0.064 | |
| regulation of programmed cell death | GO:0043067 | 152 | 0.062 | Human |
| nucleoside phosphate catabolic process | GO:1901292 | 110 | 0.061 | |
| vesicle mediated transport | GO:0016192 | 381 | 0.060 | |
| positive regulation of cysteine type endopeptidase activity | GO:2001056 | 24 | 0.059 | |
| cell proliferation | GO:0008283 | 299 | 0.056 | Mouse |
| appendage development | GO:0048736 | 401 | 0.054 | Zebrafish |
| reproductive system development | GO:0061458 | 74 | 0.053 | Mouse |
| notch receptor processing | GO:0007220 | 13 | 0.053 | |
| positive regulation of cellular component biogenesis | GO:0044089 | 80 | 0.052 | |
| imaginal disc derived wing morphogenesis | GO:0007476 | 337 | 0.050 | |
| circulatory system development | GO:0072359 | 82 | 0.049 | |
| regulation of phosphatase activity | GO:0010921 | 3 | 0.049 | |
| telencephalon development | GO:0021537 | 2 | 0.047 | |
| programmed cell death | GO:0012501 | 257 | 0.047 | Human |
| neuron projection guidance | GO:0097485 | 241 | 0.046 | |
| regulation of cell cycle | GO:0051726 | 291 | 0.045 | |
| synapse assembly | GO:0007416 | 143 | 0.044 | |
| negative regulation of cell death | GO:0060548 | 81 | 0.044 | |
| covalent chromatin modification | GO:0016569 | 106 | 0.043 | |
| morphogenesis of a branching epithelium | GO:0061138 | 45 | 0.043 | |
| organic substance catabolic process | GO:1901575 | 308 | 0.041 | Human Mouse |
| larval development | GO:0002164 | 104 | 0.041 | |
| regulation of cellular protein metabolic process | GO:0032268 | 243 | 0.041 | |
| induction of programmed cell death by hormones | GO:0035081 | 12 | 0.041 | |
| r7 cell differentiation | GO:0045466 | 43 | 0.040 | |
| embryo development ending in birth or egg hatching | GO:0009792 | 152 | 0.040 | Mouse |
| tissue morphogenesis | GO:0048729 | 297 | 0.040 | Mouse |
| connective tissue development | GO:0061448 | 3 | 0.038 | |
| gene silencing by rna | GO:0031047 | 57 | 0.038 | |
| internal protein amino acid acetylation | GO:0006475 | 38 | 0.037 | |
| respiratory system development | GO:0060541 | 213 | 0.037 | |
| protein maturation | GO:0051604 | 71 | 0.037 | |
| posttranscriptional regulation of gene expression | GO:0010608 | 145 | 0.035 | Human Mouse |
| nucleobase containing small molecule metabolic process | GO:0055086 | 174 | 0.035 | |
| positive regulation of nucleic acid templated transcription | GO:1903508 | 266 | 0.035 | Mouse |
| purine ribonucleoside metabolic process | GO:0046128 | 127 | 0.034 | |
| positive regulation of protein metabolic process | GO:0051247 | 128 | 0.034 | |
| regulation of phosphate metabolic process | GO:0019220 | 210 | 0.034 | |
| regulation of response to dna damage stimulus | GO:2001020 | 23 | 0.034 | Human |
| cell death | GO:0008219 | 279 | 0.034 | Human |
| dosage compensation | GO:0007549 | 16 | 0.034 | |
| histone h4 k16 acetylation | GO:0043984 | 4 | 0.034 | |
| compound eye photoreceptor development | GO:0042051 | 78 | 0.033 | |
| small molecule metabolic process | GO:0044281 | 305 | 0.033 | |
| peptidyl amino acid modification | GO:0018193 | 105 | 0.033 | |
| cell division | GO:0051301 | 248 | 0.033 | |
| induction of programmed cell death by ecdysone | GO:0035078 | 12 | 0.032 | |
| spermatogenesis | GO:0007283 | 200 | 0.032 | |
| regulation of phosphorus metabolic process | GO:0051174 | 210 | 0.032 | |
| positive regulation of phosphate metabolic process | GO:0045937 | 139 | 0.032 | |
| apoptotic process | GO:0006915 | 159 | 0.032 | Human |
| receptor clustering | GO:0043113 | 3 | 0.031 | |
| forebrain development | GO:0030900 | 2 | 0.031 | |
| negative regulation of biosynthetic process | GO:0009890 | 277 | 0.030 | Human Mouse |
| eye photoreceptor cell differentiation | GO:0001754 | 145 | 0.030 | |
| sulfur compound metabolic process | GO:0006790 | 59 | 0.030 | |
| eye photoreceptor cell development | GO:0042462 | 81 | 0.029 | |
| regulation of nervous system development | GO:0051960 | 248 | 0.029 | |
| nucleoside metabolic process | GO:0009116 | 127 | 0.029 | |
| cytoplasmic transport | GO:0016482 | 130 | 0.029 | Human |
| regulation of imaginal disc growth | GO:0045570 | 26 | 0.029 | |
| hemopoiesis | GO:0030097 | 46 | 0.028 | Zebrafish |
| carboxylic acid metabolic process | GO:0019752 | 92 | 0.028 | |
| negative regulation of signal transduction | GO:0009968 | 206 | 0.027 | Human |
| negative regulation of nitrogen compound metabolic process | GO:0051172 | 265 | 0.027 | Human Mouse |
| compound eye morphogenesis | GO:0001745 | 249 | 0.027 | |
| male gamete generation | GO:0048232 | 201 | 0.026 | |
| positive regulation of multicellular organismal process | GO:0051240 | 143 | 0.026 | |
| open tracheal system development | GO:0007424 | 204 | 0.025 | |
| terminal branching open tracheal system | GO:0007430 | 17 | 0.025 | |
| cell fate specification | GO:0001708 | 71 | 0.025 | |
| purine ribonucleoside triphosphate metabolic process | GO:0009205 | 119 | 0.025 | |
| macromolecule catabolic process | GO:0009057 | 161 | 0.024 | Human Mouse |
| purine ribonucleoside catabolic process | GO:0046130 | 112 | 0.024 | |
| brain development | GO:0007420 | 120 | 0.024 | |
| spindle organization | GO:0007051 | 253 | 0.024 | |
| positive regulation of cellular amino acid metabolic process | GO:0045764 | 0 | 0.024 | |
| nucleoside triphosphate catabolic process | GO:0009143 | 108 | 0.024 | |
| regulation of cellular response to stress | GO:0080135 | 89 | 0.024 | Human |
| single organism behavior | GO:0044708 | 391 | 0.023 | |
| positive regulation of peptidase activity | GO:0010952 | 29 | 0.023 | |
| peptidyl lysine methylation | GO:0018022 | 16 | 0.023 | |
| carbohydrate derivative biosynthetic process | GO:1901137 | 85 | 0.023 | |
| ion homeostasis | GO:0050801 | 55 | 0.023 | Mouse |
| single organism biosynthetic process | GO:0044711 | 206 | 0.022 | |
| macromolecular complex assembly | GO:0065003 | 256 | 0.022 | Human |
| purine nucleoside triphosphate catabolic process | GO:0009146 | 108 | 0.022 | |
| mitotic nuclear division | GO:0007067 | 213 | 0.022 | |
| negative regulation of rna metabolic process | GO:0051253 | 251 | 0.022 | Human Mouse |
| sex differentiation | GO:0007548 | 81 | 0.021 | |
| death | GO:0016265 | 284 | 0.021 | Human |
| pigmentation | GO:0043473 | 75 | 0.021 | |
| synaptic vesicle localization | GO:0097479 | 53 | 0.020 | |
| positive regulation of rna metabolic process | GO:0051254 | 271 | 0.020 | Mouse |
| positive regulation of macromolecule biosynthetic process | GO:0010557 | 283 | 0.020 | Mouse |
| ribonucleoside metabolic process | GO:0009119 | 127 | 0.020 | |
| regulation of notch signaling pathway | GO:0008593 | 100 | 0.020 | |
| segment polarity determination | GO:0007367 | 25 | 0.020 | |
| ribose phosphate metabolic process | GO:0019693 | 145 | 0.020 | |
| regulation of chromatin silencing | GO:0031935 | 36 | 0.019 | |
| posttranscriptional gene silencing | GO:0016441 | 46 | 0.019 | |
| imaginal disc growth | GO:0007446 | 37 | 0.019 | |
| ribonucleoside triphosphate metabolic process | GO:0009199 | 119 | 0.019 | |
| periodic partitioning | GO:0007365 | 29 | 0.019 | |
| nucleoside triphosphate metabolic process | GO:0009141 | 120 | 0.019 | |
| negative regulation of fibroblast growth factor receptor signaling pathway | GO:0040037 | 2 | 0.019 | |
| positive regulation of hydrolase activity | GO:0051345 | 78 | 0.019 | |
| negative regulation of cell differentiation | GO:0045596 | 143 | 0.018 | |
| response to extracellular stimulus | GO:0009991 | 116 | 0.018 | Mouse |
| organophosphate metabolic process | GO:0019637 | 195 | 0.018 | |
| axonogenesis | GO:0007409 | 290 | 0.018 | |
| regulation of cellular response to hypoxia | GO:1900037 | 3 | 0.018 | |
| regulation of multicellular organism growth | GO:0040014 | 40 | 0.018 | |
| positive regulation of cysteine type endopeptidase activity involved in apoptotic process | GO:0043280 | 23 | 0.017 | |
| regulation of purine nucleotide metabolic process | GO:1900542 | 62 | 0.017 | |
| positive regulation of phosphorus metabolic process | GO:0010562 | 139 | 0.017 | |
| negative regulation of catalytic activity | GO:0043086 | 42 | 0.017 | |
| small molecule biosynthetic process | GO:0044283 | 37 | 0.017 | |
| regulation of synapse structure and activity | GO:0050803 | 128 | 0.017 | |
| negative regulation of cellular macromolecule biosynthetic process | GO:2000113 | 267 | 0.017 | Human Mouse |
| regulation of organelle organization | GO:0033043 | 196 | 0.017 | |
| regulation of transcription from rna polymerase ii promoter | GO:0006357 | 378 | 0.017 | Human Zebrafish Mouse |
| nucleoside phosphate metabolic process | GO:0006753 | 162 | 0.017 | |
| cellular amino acid metabolic process | GO:0006520 | 61 | 0.016 | |
| negative regulation of apoptotic process | GO:0043066 | 63 | 0.016 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 0 | 0.016 | |
| endosomal transport | GO:0016197 | 44 | 0.016 | |
| regulation of nucleotide metabolic process | GO:0006140 | 62 | 0.016 | |
| response to biotic stimulus | GO:0009607 | 294 | 0.016 | |
| homeostatic process | GO:0042592 | 199 | 0.016 | Zebrafish Mouse |
| ecdysone mediated induction of salivary gland cell autophagic cell death | GO:0035072 | 12 | 0.015 | |
| central nervous system development | GO:0007417 | 201 | 0.015 | |
| mitochondrial membrane organization | GO:0007006 | 3 | 0.015 | |
| purine ribonucleotide metabolic process | GO:0009150 | 145 | 0.015 | |
| peptidyl lysine trimethylation | GO:0018023 | 6 | 0.015 | |
| negative regulation of chromatin silencing | GO:0031936 | 9 | 0.015 | |
| digestive system development | GO:0055123 | 149 | 0.015 | |
| columnar cuboidal epithelial cell differentiation | GO:0002065 | 256 | 0.015 | |
| regulation of cellular amine metabolic process | GO:0033238 | 3 | 0.015 | |
| amine metabolic process | GO:0009308 | 12 | 0.015 | |
| regulation of cysteine type endopeptidase activity | GO:2000116 | 27 | 0.015 | |
| ribonucleoside triphosphate catabolic process | GO:0009203 | 108 | 0.015 | |
| regulation of endopeptidase activity | GO:0052548 | 36 | 0.015 | |
| regulation of epithelial cell proliferation | GO:0050678 | 4 | 0.015 | |
| positive regulation of gene expression | GO:0010628 | 290 | 0.015 | Mouse |
| reproductive structure development | GO:0048608 | 74 | 0.014 | Mouse |
| chemotaxis | GO:0006935 | 249 | 0.014 | |
| regulation of eye photoreceptor cell development | GO:0042478 | 13 | 0.014 | |
| cellular protein catabolic process | GO:0044257 | 83 | 0.014 | |
| cellular response to abiotic stimulus | GO:0071214 | 58 | 0.014 | |
| purine nucleotide catabolic process | GO:0006195 | 109 | 0.014 | |
| organ growth | GO:0035265 | 56 | 0.014 | |
| protein localization | GO:0008104 | 284 | 0.014 | Human |
| negative regulation of wnt signaling pathway | GO:0030178 | 28 | 0.014 | |
| response to organic substance | GO:0010033 | 284 | 0.013 | Human Mouse |
| purine containing compound metabolic process | GO:0072521 | 155 | 0.013 | |
| establishment of localization in cell | GO:0051649 | 402 | 0.013 | Human |
| induction of programmed cell death | GO:0012502 | 12 | 0.013 | |
| organic acid metabolic process | GO:0006082 | 103 | 0.013 | |
| rna splicing | GO:0008380 | 83 | 0.013 | |
| epithelial cell development | GO:0002064 | 274 | 0.013 | |
| purine containing compound catabolic process | GO:0072523 | 112 | 0.013 | |
| cellular response to chemical stimulus | GO:0070887 | 199 | 0.013 | Human Mouse |
| developmental growth involved in morphogenesis | GO:0060560 | 65 | 0.013 | Mouse |
| multicellular organism growth | GO:0035264 | 46 | 0.013 | |
| nucleotide metabolic process | GO:0009117 | 161 | 0.012 | |
| regulation of cell differentiation | GO:0045595 | 302 | 0.012 | |
| regulation of cell proliferation | GO:0042127 | 163 | 0.012 | Mouse |
| regulation of ion transport | GO:0043269 | 39 | 0.012 | |
| cellular response to oxygen containing compound | GO:1901701 | 79 | 0.012 | Mouse |
| positive regulation of developmental growth | GO:0048639 | 62 | 0.012 | |
| digestive tract development | GO:0048565 | 149 | 0.012 | |
| synaptic transmission | GO:0007268 | 288 | 0.012 | |
| positive regulation of gene expression epigenetic | GO:0045815 | 16 | 0.012 | |
| nucleoside catabolic process | GO:0009164 | 112 | 0.012 | |
| exocrine system development | GO:0035272 | 162 | 0.012 | |
| regulation of protein localization | GO:0032880 | 76 | 0.011 | Human |
| histolysis | GO:0007559 | 102 | 0.011 | |
| heterocycle catabolic process | GO:0046700 | 166 | 0.011 | |
| head development | GO:0060322 | 135 | 0.011 | |
| positive regulation of cellular component organization | GO:0051130 | 156 | 0.011 | |
| nucleobase containing compound catabolic process | GO:0034655 | 165 | 0.011 | |
| lipid metabolic process | GO:0006629 | 121 | 0.011 | |
| regulation of protein ubiquitination | GO:0031396 | 22 | 0.011 | |
| tube morphogenesis | GO:0035239 | 191 | 0.011 | |
| ovarian follicle cell development | GO:0030707 | 248 | 0.011 | |
| trachea morphogenesis | GO:0060439 | 22 | 0.011 | |
| cellular nitrogen compound catabolic process | GO:0044270 | 165 | 0.011 | |
| sensory organ morphogenesis | GO:0090596 | 260 | 0.011 | |
| imaginal disc derived wing margin morphogenesis | GO:0008587 | 41 | 0.011 | |
| regulation of developmental growth | GO:0048638 | 174 | 0.011 | |
| phosphorylation | GO:0016310 | 294 | 0.011 | Mouse |
| cytoskeleton dependent intracellular transport | GO:0030705 | 44 | 0.010 | |
| regulation of compound eye photoreceptor development | GO:0045314 | 12 | 0.010 | |
| cell activation | GO:0001775 | 9 | 0.010 | |
| golgi vesicle transport | GO:0048193 | 27 | 0.010 | |
| positive regulation of purine nucleotide metabolic process | GO:1900544 | 55 | 0.010 | |
| positive regulation of transcription dna templated | GO:0045893 | 266 | 0.010 | Mouse |
| necrotic cell death | GO:0070265 | 1 | 0.010 | |
| localization of cell | GO:0051674 | 257 | 0.010 | |
| regulation of alternative mrna splicing via spliceosome | GO:0000381 | 60 | 0.010 | |