Drosophila melanogaster

147 known processes

Sir2 (Dmel_CG5216)

CG5216 gene product from transcript CG5216-RA

(Aliases: sir2,BEST:LD38188,Dmel\CG5216,CG5216,dSir2,l(2)05326,dSIR2,SIR2,Sir2L,D.mel1,dsir2,dmSRT406,DSir2)

Sir2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
chromatin organizationGO:00063252071.000
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.998
chromosome organizationGO:00512763600.998
negative regulation of cellular biosynthetic processGO:00313272770.996
negative regulation of rna biosynthetic processGO:19026792400.994
chromatin silencingGO:0006342760.992
histone modificationGO:00165701060.992
negative regulation of biosynthetic processGO:00098902770.991
negative regulation of macromolecule biosynthetic processGO:00105582700.988
negative regulation of gene expression epigeneticGO:0045814770.977
chromatin modificationGO:00165681470.969
negative regulation of nucleic acid templated transcriptionGO:19035072400.968
response to organic substanceGO:00100332840.968
gene silencingGO:00164581380.967
regulation of gene expression epigeneticGO:00400291280.962
negative regulation of rna metabolic processGO:00512532510.957
negative regulation of gene expressionGO:00106293870.955
cellular response to chemical stimulusGO:00708871990.953
Human Mouse
cellular catabolic processGO:00442483720.948
Human Mouse
negative regulation of nitrogen compound metabolic processGO:00511722650.937
intracellular signal transductionGO:00355563000.932
Human Mouse
histone acetylationGO:0016573380.928
negative regulation of cell communicationGO:00106482230.927
Human Mouse
negative regulation of cellular metabolic processGO:00313243820.911
regulation of organelle organizationGO:00330431960.907
response to oxygen containing compoundGO:19017002000.902
regulation of transcription from rna polymerase ii promoterGO:00063573780.846
Human Mouse
positive regulation of nitrogen compound metabolic processGO:00511733540.842
Human Mouse
covalent chromatin modificationGO:00165691060.840
negative regulation of transcription dna templatedGO:00458922370.839
protein acetylationGO:0006473390.815
protein acylationGO:0043543420.815
positive regulation of rna metabolic processGO:00512542710.813
Human Mouse
positive regulation of response to stimulusGO:00485843230.794
negative regulation of signalingGO:00230572190.785
Human Mouse
peptidyl lysine acetylationGO:0018394390.772
positive regulation of cellular biosynthetic processGO:00313283160.771
Human Mouse
peptidyl amino acid modificationGO:00181931050.764
positive regulation of nucleobase containing compound metabolic processGO:00459353320.754
Human Mouse
single organism cellular localizationGO:19025801800.745
Human
regulation of cellular response to stressGO:0080135890.744
Human Mouse
muscle structure developmentGO:00610612240.720
regulation of cell differentiationGO:00455953020.713
Mouse
positive regulation of macromolecule metabolic processGO:00106044050.707
Human Mouse
cell deathGO:00082192790.698
positive regulation of nucleic acid templated transcriptionGO:19035082660.677
Human Mouse
positive regulation of autophagyGO:0010508210.664
Human Mouse
protein localization to organelleGO:0033365820.663
Human
transcription from rna polymerase ii promoterGO:00063663680.662
Human Mouse
growthGO:00400073590.645
Human
negative regulation of nucleobase containing compound metabolic processGO:00459342610.618
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.606
Human Mouse
positive regulation of organelle organizationGO:0010638650.601
Human
positive regulation of macromolecule biosynthetic processGO:00105572830.581
Human Mouse
response to endogenous stimulusGO:00097191190.572
Human Mouse
determination of adult lifespanGO:00083401370.550
regulation of cell cycle processGO:00105641810.547
negative regulation of signal transductionGO:00099682060.547
Human Mouse
intracellular transportGO:00469072280.537
Human
cellular response to dna damage stimulusGO:00069742230.525
Human Mouse
regulation of cell developmentGO:00602842150.521
protein localization to nucleusGO:0034504550.517
Human
heterocycle catabolic processGO:00467001660.516
Human
negative regulation of neuron deathGO:1901215180.513
Mouse
jnk cascadeGO:0007254500.512
positive regulation of transcription dna templatedGO:00458932660.512
Human Mouse
regionalizationGO:00030024160.504
cellular response to starvationGO:0009267610.495
Human Mouse
regulation of apoptotic processGO:00429811300.495
catabolic processGO:00090564090.494
Human Mouse
cellular macromolecule localizationGO:00707272200.484
Human
regulation of response to stressGO:00801342000.456
Human Mouse
protein localization to chromatinGO:007116830.433
response to alcoholGO:0097305950.423
regulation of intracellular signal transductionGO:19025312360.416
Human Mouse
cellular protein localizationGO:00346131600.406
Human
internal peptidyl lysine acetylationGO:0018393380.398
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630110.392
Human Mouse
cellular response to ionizing radiationGO:0071479150.381
Mouse
regulation of catabolic processGO:00098941700.375
Human Mouse
internal protein amino acid acetylationGO:0006475380.371
cell type specific apoptotic processGO:0097285380.366
Mouse
regulation of chromosome organizationGO:0033044640.366
regulation of histone modificationGO:0031056200.365
cell migrationGO:00164772380.355
cellular protein modification processGO:00064644380.352
response to nitrogen compoundGO:1901698900.344
Human Mouse
positive regulation of gene expressionGO:00106282900.339
Human Mouse
positive regulation of biosynthetic processGO:00098913160.337
Human Mouse
response to organonitrogen compoundGO:0010243750.330
Human Mouse
male gamete generationGO:00482322010.327
Mouse
positive regulation of developmental processGO:00510941430.317
Human
heterochromatin organizationGO:0070828250.313
spindle organizationGO:00070512530.309
response to organic cyclic compoundGO:0014070890.299
Human
regulation of anatomical structure morphogenesisGO:00226032420.289
response to ionizing radiationGO:0010212320.289
Mouse
regulation of cell deathGO:00109411730.287
establishment of protein localizationGO:00451841630.274
Human
immune responseGO:00069552460.266
Human
negative regulation of cell differentiationGO:00455961430.263
Mouse
protein modification processGO:00362114380.263
eye morphogenesisGO:00485922600.258
dna damage checkpointGO:0000077780.257
regulation of autophagyGO:0010506620.248
Human Mouse
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.248
Human Mouse
peptidyl lysine modificationGO:0018205570.248
cellular response to insulin stimulusGO:0032869280.238
Human
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092380.236
Mouse
protein targetingGO:0006605640.223
Human
cellular response to nutrient levelsGO:0031669620.215
Human Mouse
autophagyGO:00069141080.212
Human Mouse
stress activated mapk cascadeGO:0051403520.209
response to lipidGO:0033993380.207
Human
histone h4 k16 acetylationGO:004398440.205
regulation of stress activated mapk cascadeGO:0032872410.203
positive regulation of catabolic processGO:00098961050.203
Human Mouse
regulation of growthGO:00400082330.200
Human
positive regulation of phosphorus metabolic processGO:00105621390.199
Human Mouse
protein complex biogenesisGO:00702712010.199
deathGO:00162652840.199
localization of cellGO:00516742570.196
regulation of cellular ketone metabolic processGO:001056530.193
Mouse
macromolecular complex assemblyGO:00650032560.188
regulation of multicellular organismal developmentGO:20000264140.186
adult behaviorGO:00305341370.181
regulation of cellular catabolic processGO:00313291570.181
Human Mouse
organelle fissionGO:00482853400.180
cellular macromolecular complex assemblyGO:00346221530.176
regulation of protein metabolic processGO:00512462560.174
positive regulation of multicellular organismal processGO:00512401430.168
positive regulation of rna biosynthetic processGO:19026802660.167
Human Mouse
camera type eye morphogenesisGO:004859320.163
response to extracellular stimulusGO:00099911160.161
response to bacteriumGO:00096171980.159
positive regulation of response to external stimulusGO:0032103440.158
Human Mouse
regulation of cellular amino acid metabolic processGO:000652100.154
response to abiotic stimulusGO:00096283410.154
Human Mouse
regulation of histone acetylationGO:003506570.152
response to sterolGO:0036314340.151
protein targeting to nucleusGO:0044744510.151
Human
single organism catabolic processGO:00447122280.150
Human Mouse
stress activated protein kinase signaling cascadeGO:0031098550.150
regulation of chromatin organizationGO:1902275320.147
protein transportGO:00150311550.147
Human
regulation of cell cycle phase transitionGO:19019871300.145
regulation of chromatin modificationGO:1903308280.144
single organism behaviorGO:00447083910.143
purine nucleoside catabolic processGO:00061521120.140
male pronucleus assemblyGO:003503960.139
positive regulation of multicellular organism growthGO:0040018210.138
negative regulation of programmed cell deathGO:0043069720.137
Human Mouse
negative regulation of apoptotic processGO:0043066630.132
Human Mouse
columnar cuboidal epithelial cell differentiationGO:00020652560.132
negative regulation of organelle organizationGO:0010639560.130
protein localizationGO:00081042840.129
Human
regulation of immune system processGO:00026821760.127
Human
eye developmentGO:00016543230.126
positive regulation of macroautophagyGO:001623980.125
Human Mouse
regulation of cellular amine metabolic processGO:003323830.125
organic substance catabolic processGO:19015753080.124
Human
positive regulation of multi organism processGO:0043902400.122
dna packagingGO:0006323910.122
purine ribonucleotide catabolic processGO:00091541090.118
response to other organismGO:00517072930.117
rhythmic processGO:00485111060.116
Human Mouse
cell motilityGO:00488702510.115
regulation of phosphorylationGO:00423251470.114
Human Mouse
regulation of jnk cascadeGO:0046328400.112
cellular macromolecule catabolic processGO:00442651360.111
Human
purine nucleoside triphosphate metabolic processGO:00091441190.110
regulation of dna metabolic processGO:0051052340.110
Human
regulation of notch signaling pathwayGO:00085931000.109
dna metabolic processGO:00062592270.107
Human Mouse
photoreceptor cell differentiationGO:00465301700.106
dna integrity checkpointGO:0031570810.106
developmental growthGO:00485892800.104
positive regulation of cellular catabolic processGO:0031331950.100
Human Mouse
establishment of localization in cellGO:00516494020.099
Human
epithelial cell differentiationGO:00308553220.098
positive regulation of immune responseGO:0050778630.098
Human
stem cell maintenanceGO:0019827670.097
cellular response to organic substanceGO:00713101320.096
Human Mouse
regulation of programmed cell deathGO:00430671520.096
regulation of neuron deathGO:1901214260.094
Mouse
nucleoside triphosphate metabolic processGO:00091411200.092
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178650.091
Mouse
nucleobase containing compound catabolic processGO:00346551650.090
Human
pigmentationGO:0043473750.090
negative regulation of cellular component organizationGO:00511291080.089
chromatin remodelingGO:0006338720.089
Human
purine ribonucleoside triphosphate metabolic processGO:00092051190.088
positive regulation of cell communicationGO:00106472500.087
Human Mouse
mitotic nuclear divisionGO:00070672130.087
dendrite morphogenesisGO:00488131990.086
rna catabolic processGO:0006401370.086
regulation of cellular component biogenesisGO:00440872010.086
cellular ketone metabolic processGO:0042180240.085
Mouse
macroautophagyGO:0016236420.085
Human Mouse
positive regulation of antimicrobial peptide biosynthetic processGO:0002807260.082
macromolecule catabolic processGO:00090571610.082
Human
response to external biotic stimulusGO:00432072930.082
embryonic morphogenesisGO:00485982060.081
negative regulation of chromatin silencingGO:003193690.080
protein complex assemblyGO:00064612000.080
regulation of response to external stimulusGO:00321011150.079
Human Mouse
regulation of chromatin silencingGO:0031935360.078
Human
multicellular organism growthGO:0035264460.078
nucleotide catabolic processGO:00091661090.077
regulation of phosphorus metabolic processGO:00511742100.077
Human Mouse
glial cell differentiationGO:0010001350.076
signal transduction by phosphorylationGO:00230141070.075
regulation of stress activated protein kinase signaling cascadeGO:0070302420.075
regulation of cell cycleGO:00517262910.074
Human
myotube differentiationGO:0014902460.074
sex differentiationGO:0007548810.073
Mouse
heterochromatin organization involved in chromatin silencingGO:007086890.073
reproductive structure developmentGO:0048608740.073
Mouse
establishment of protein localization to organelleGO:0072594620.072
Human
programmed cell deathGO:00125012570.072
vesicle mediated transportGO:00161923810.071
response to starvationGO:0042594970.071
Human Mouse
purine ribonucleotide metabolic processGO:00091501450.070
mapk cascadeGO:00001651070.069
intracellular protein transportGO:00068861040.069
Human
regulation of multicellular organism growthGO:0040014400.069
purine nucleoside metabolic processGO:00422781270.068
positive regulation of growthGO:0045927750.068
compound eye photoreceptor cell differentiationGO:00017511400.067
amine metabolic processGO:0009308120.066
cell divisionGO:00513012480.065
camera type eye developmentGO:004301040.065
negative regulation of response to stimulusGO:00485852580.064
Human Mouse
stem cell developmentGO:0048864790.063
regulation of macroautophagyGO:0016241150.061
Human Mouse
regulation of epithelial cell differentiationGO:003085640.061
regulation of organ morphogenesisGO:2000027780.059
nuclear divisionGO:00002803320.059
regulation of defense responseGO:00313471020.057
apoptotic signaling pathwayGO:0097190270.055
Human Mouse
regulation of small gtpase mediated signal transductionGO:0051056930.055
compound eye developmentGO:00487493070.055
response to virusGO:0009615280.054
neurological system processGO:00508773580.054
epithelial cell developmentGO:00020642740.054
cellular response to endogenous stimulusGO:0071495800.054
Human Mouse
positive regulation of signal transductionGO:00099672230.054
Human
proteolysisGO:00065081920.053
Human
response to biotic stimulusGO:00096072940.053
embryo development ending in birth or egg hatchingGO:00097921520.053
morphogenesis of a branching epitheliumGO:0061138450.052
organic substance transportGO:00717022570.052
Human Mouse
regulation of phosphate metabolic processGO:00192202100.052
Human Mouse
protein alkylationGO:0008213430.052
Human
notch signaling pathwayGO:00072191200.051
establishment or maintenance of cell polarityGO:00071631670.050
response to ketoneGO:1901654340.050
Human
positive regulation of protein metabolic processGO:00512471280.050
Human Mouse
positive regulation of programmed cell deathGO:0043068620.050
Human Mouse
response to lipopolysaccharideGO:003249640.049
endocytosisGO:00068973100.049
cellular protein complex assemblyGO:0043623710.048
negative regulation of protein metabolic processGO:0051248850.048
Human
eye photoreceptor cell differentiationGO:00017541450.048
hemopoiesisGO:0030097460.047
purine nucleotide catabolic processGO:00061951090.047
regulation of mapk cascadeGO:0043408920.047
phagocytosisGO:00069092150.047
head developmentGO:00603221350.046
nucleoside catabolic processGO:00091641120.046
purine nucleoside triphosphate catabolic processGO:00091461080.046
defense responseGO:00069523000.046
single organism membrane organizationGO:0044802930.046
secondary metabolic processGO:0019748750.045
posttranscriptional regulation of gene expressionGO:00106081450.045
Mouse
organonitrogen compound catabolic processGO:19015651280.045
positive regulation of phosphate metabolic processGO:00459371390.045
Human Mouse
negative regulation of developmental processGO:00510932010.044
Human Mouse
glycosyl compound catabolic processGO:19016581120.044
columnar cuboidal epithelial cell developmentGO:00020662490.043
nuclear importGO:0051170510.043
Human
positive regulation of phosphorylationGO:0042327870.043
Human Mouse
central nervous system developmentGO:00074172010.042
regulation of proteolysisGO:0030162870.042
Human
multi multicellular organism processGO:00447061230.042
behavioral response to ethanolGO:0048149490.042
positive regulation of jun kinase activityGO:004350740.042
muscle cell differentiationGO:00426921030.041
organophosphate metabolic processGO:00196371950.041
positive regulation of molecular functionGO:00440931360.041
Human Mouse
protein dna complex subunit organizationGO:0071824860.041
regulation of peptidyl lysine acetylationGO:200075670.040
syncytium formation by plasma membrane fusionGO:0000768430.040
cellular response to nitrogen compoundGO:1901699510.040
Human
positive regulation of response to extracellular stimulusGO:003210680.040
Human Mouse
immune system developmentGO:0002520570.039
dna replicationGO:0006260480.039
innate immune responseGO:00450871440.039
purine ribonucleoside metabolic processGO:00461281270.039
carbohydrate derivative catabolic processGO:19011361180.039
ribonucleoside triphosphate metabolic processGO:00091991190.039
appendage developmentGO:00487364010.039
organic cyclic compound catabolic processGO:19013611680.038
Human
ribonucleotide catabolic processGO:00092611090.038
cytoplasmic transportGO:00164821300.038
Human
agingGO:00075681430.038
convergent extensionGO:006002620.037
single organism intracellular transportGO:19025822070.037
Human
gliogenesisGO:0042063800.037
single organism nuclear importGO:1902593510.037
Human
organophosphate catabolic processGO:00464341120.037
organonitrogen compound metabolic processGO:19015643180.037
carbohydrate derivative metabolic processGO:19011352170.036
chromatin assemblyGO:0031497480.036
regulation of protein modification processGO:00313991120.035
ribonucleotide metabolic processGO:00092591450.035
ribonucleoside triphosphate catabolic processGO:00092031080.035
cell cycle checkpointGO:0000075950.035
regulation of transportGO:00510491810.035
Human Mouse
positive regulation of mapk cascadeGO:0043410630.035
regulation of transforming growth factor beta receptor signaling pathwayGO:001701560.034
Mouse
ras protein signal transductionGO:0007265880.034
tube developmentGO:00352952440.033
positive regulation of nervous system developmentGO:0051962690.033
positive regulation of cellular component organizationGO:00511301560.033
Human
positive regulation of developmental growthGO:0048639620.032
nucleoside metabolic processGO:00091161270.032
positive regulation of cellular protein metabolic processGO:00322701180.032
Human Mouse
regulation of catalytic activityGO:00507901850.032
Human Mouse
regulation of transcription by chromatin organizationGO:003440130.032
positive regulation of histone acetylationGO:003506630.032
response to woundingGO:0009611940.031
myoblast fusionGO:0007520430.031
brain developmentGO:00074201200.031
cell proliferationGO:00082832990.031
Human
cell fate specificationGO:0001708710.031
regulation of defense response to virus by hostGO:0050691100.031
oxoacid metabolic processGO:00434361030.030
Mouse
macromolecule deacylationGO:0098732110.030
positive regulation of transportGO:0051050920.030
Mouse
negative regulation of cellular protein metabolic processGO:0032269850.030
Human
regulation of developmental pigmentationGO:0048070240.030
ameboidal type cell migrationGO:00016671510.029
cellular amino acid metabolic processGO:0006520610.029
muscle organ developmentGO:00075171270.029
response to transforming growth factor betaGO:0071559180.028
Mouse
digestive system developmentGO:00551231490.028
protein import into nucleusGO:0006606510.028
Human
cellular response to organic cyclic compoundGO:0071407320.028
Human
organic acid metabolic processGO:00060821030.027
Mouse
aromatic compound catabolic processGO:00194391660.027
Human
posttranscriptional gene silencingGO:0016441460.027
response to hormoneGO:0009725450.027
Human Mouse
purine containing compound catabolic processGO:00725231120.027
development of primary sexual characteristicsGO:0045137500.027
Mouse
organelle assemblyGO:00709251980.027
positive regulation of catalytic activityGO:00430851180.026
Human Mouse
compound eye photoreceptor developmentGO:0042051780.026
purine ribonucleoside triphosphate catabolic processGO:00092071080.026
nucleobase containing small molecule metabolic processGO:00550861740.026
carboxylic acid metabolic processGO:0019752920.026
Mouse
cellular response to radiationGO:0071478520.026
Mouse
stem cell differentiationGO:00488631170.025
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052240.025
telencephalon developmentGO:002153720.025
positive regulation of signalingGO:00230562430.025
Human
positive regulation of intracellular signal transductionGO:19025331160.025
nucleoside triphosphate catabolic processGO:00091431080.025
regulation of jun kinase activityGO:004350680.025
chromatin mediated maintenance of transcriptionGO:004809670.024
neural precursor cell proliferationGO:0061351750.024
developmental pigmentationGO:0048066680.024
cellular protein catabolic processGO:0044257830.023
Human
regulation of apoptotic signaling pathwayGO:2001233100.023
Human Mouse
hindbrain developmentGO:003090220.023
transforming growth factor beta receptor signaling pathwayGO:0007179160.023
Mouse
body morphogenesisGO:001017120.023
regulation of photoreceptor cell differentiationGO:0046532340.022
cellular amine metabolic processGO:0044106120.022
cellular response to lipidGO:0071396200.022
Human
photoreceptor cell developmentGO:0042461960.022
negative regulation of multicellular organismal processGO:00512411420.022
sensory organ morphogenesisGO:00905962600.021
gland developmentGO:00487321910.021
ubiquitin dependent protein catabolic processGO:0006511780.021
Human
imaginal disc derived wing morphogenesisGO:00074763370.021
cellular nitrogen compound catabolic processGO:00442701650.021
Human
apoptotic processGO:00069151590.021
mrna catabolic processGO:0006402330.021
positive regulation of response to biotic stimulusGO:0002833310.021
regulation of immune effector processGO:0002697520.021
enzyme linked receptor protein signaling pathwayGO:00071671790.021
Human Mouse
small molecule metabolic processGO:00442813050.021
Mouse
regulation of sequence specific dna binding transcription factor activityGO:0051090120.020
Human
purine ribonucleoside catabolic processGO:00461301120.020
negative regulation of notch signaling pathwayGO:0045746410.020
prostaglandin biosynthetic processGO:000151610.020
Mouse
retina development in camera type eyeGO:006004140.020
cellular response to extracellular stimulusGO:0031668640.020
Human Mouse
immune system processGO:00023763470.020
Human
positive regulation of neurogenesisGO:0050769410.019
response to insulinGO:0032868290.019
Human Mouse
epithelial cell migrationGO:00106311480.019
cellular response to oxidative stressGO:0034599280.019
Human
gonad developmentGO:0008406500.019
Mouse
positive regulation of immune system processGO:0002684680.019
Human
purine containing compound metabolic processGO:00725211550.019
inositol lipid mediated signalingGO:004801740.018
intrinsic apoptotic signaling pathwayGO:0097193160.018
Human Mouse
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101180.018
Mouse
atp dependent chromatin remodelingGO:0043044220.018
organ growthGO:0035265560.018
positive regulation of production of molecular mediator of immune responseGO:0002702280.018
ribose phosphate metabolic processGO:00196931450.018
wound healingGO:0042060750.018
positive regulation of proteolysisGO:0045862520.018
Human
autophagic vacuole fusionGO:0000046150.017
purine nucleotide metabolic processGO:00061631460.017
positive regulation of cell differentiationGO:0045597640.017
negative regulation of protein processingGO:0010955310.017
regulation of developmental growthGO:00486381740.017
nucleosome positioningGO:001658430.017
humoral immune responseGO:00069591170.017
mitotic spindle organizationGO:00070522200.017
dna methylationGO:000630640.016
dorsal ventral pattern formationGO:00099531330.016
methylationGO:0032259470.016
Human
regulation of nucleocytoplasmic transportGO:0046822350.016
Human
regulation of hydrolase activityGO:0051336970.016
Human
forebrain developmentGO:003090020.016
dna methylation or demethylationGO:004472840.016
pigment metabolic processGO:0042440840.016
regulation of cell morphogenesisGO:00226041630.016
interspecies interaction between organismsGO:0044419160.016
regulation of dna replicationGO:0006275130.015
regulation of dna templated transcription in response to stressGO:004362040.015
positive regulation of cellular amino acid metabolic processGO:004576400.015
positive regulation of gene expression epigeneticGO:0045815160.015
chromatin assembly or disassemblyGO:0006333520.015
regulation of reproductive processGO:2000241540.015
connective tissue developmentGO:006144830.015
nurse cell apoptotic processGO:0045476170.015
negative regulation of intracellular signal transductionGO:1902532570.015
Human Mouse
mitotic cell cycle checkpointGO:0007093880.015
positive regulation of cell cycleGO:0045787430.015
regulation of neuron apoptotic processGO:0043523160.014
compound eye morphogenesisGO:00017452490.014
organelle inheritanceGO:004830820.014
ribonucleoside catabolic processGO:00424541120.014
cellular response to oxygen containing compoundGO:1901701790.014
Human
regulation of purine nucleotide metabolic processGO:1900542620.014
regulation of compound eye cone cell fate specificationGO:004268240.014
defense response to bacteriumGO:00427421780.014
dendrite developmentGO:00163582040.014
signal transduction in response to dna damageGO:004277030.014
Human
mesoderm developmentGO:0007498780.014
protein catabolic processGO:00301631010.014
Human
anterior posterior pattern specificationGO:00099521360.014
tissue morphogenesisGO:00487292970.014
negative regulation of defense responseGO:0031348350.014
regulation of phosphatase activityGO:001092130.014
multi organism reproductive behaviorGO:00447051210.014
axis specificationGO:00097981670.014
nucleosome organizationGO:0034728590.013
regulation of cell motilityGO:2000145230.013
regulation of chromatin assemblyGO:001084790.013
modification dependent protein catabolic processGO:0019941780.013
Human
response to peptideGO:1901652290.013
Human Mouse
positive regulation of cell deathGO:0010942690.013
Human Mouse
circadian rhythmGO:00076231050.013
Human Mouse
regulation of molecular functionGO:00650092170.013
Human Mouse
regulation of localizationGO:00328792750.013
Human Mouse
protein kinase b signalingGO:004349110.013
Human Mouse
dna conformation changeGO:00711031050.013
nucleoside phosphate catabolic processGO:19012921100.013
negative regulation of small gtpase mediated signal transductionGO:0051058130.013
mitochondrial membrane organizationGO:000700630.013
membrane organizationGO:00610241120.012
icosanoid biosynthetic processGO:004645610.012
Mouse
positive regulation of cell motilityGO:200014730.012
hematopoietic or lymphoid organ developmentGO:0048534570.012
positive regulation of cellular amine metabolic processGO:003324000.012
meiotic cell cycleGO:00513211710.012
response to ethanolGO:0045471590.012
signal transduction by p53 class mediatorGO:007233160.012
Human Mouse
larval developmentGO:00021641040.012
Worm
regulation of cellular protein metabolic processGO:00322682430.012
reproductive system developmentGO:0061458740.012
Mouse
bmp signaling pathwayGO:0030509270.012
negative regulation of neuron apoptotic processGO:0043524140.012
mitotic dna damage checkpointGO:0044773740.012
regulation of synaptic plasticityGO:0048167140.012
histone h3 acetylationGO:0043966110.012
Worm
immune response activating signal transductionGO:000275720.012
negative regulation of intrinsic apoptotic signaling pathwayGO:200124310.012
Human Mouse
cellular response to transforming growth factor beta stimulusGO:0071560180.012
Mouse
regulation of ras protein signal transductionGO:0046578930.011
mitotic sister chromatid segregationGO:0000070870.011

Sir2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.013