IMP: Integrative Multi-species Prediction

Drosophila melanogaster

0 known processes

NHP2 (Dmel_CG5258)

CG5258 gene product from transcript CG5258-RA

(Aliases: Dmel\CG5258,FBgn0029148,CG5258)

FLYBASE: FBgn0029148
Entrez: 44005
UniProtKB: Q9V3U2
UniProtKB: M9PCI2

Process Predictions
Disease Predictions

NHP2 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
rna processing	GO:0006396	147	0.562
macromolecular complex assembly	GO:0065003	256	0.198
rrna processing	GO:0006364	3	0.146
ncrna metabolic process	GO:0034660	43	0.136
positive regulation of rna metabolic process	GO:0051254	271	0.125
ribosomal large subunit biogenesis	GO:0042273	1	0.107
positive regulation of biosynthetic process	GO:0009891	316	0.088
ribonucleoprotein complex biogenesis	GO:0022613	31	0.079
positive regulation of cellular biosynthetic process	GO:0031328	316	0.075
positive regulation of rna biosynthetic process	GO:1902680	266	0.075
vesicle mediated transport	GO:0016192	381	0.071
organelle assembly	GO:0070925	198	0.068
mrna metabolic process	GO:0016071	124	0.067
macromolecule catabolic process	GO:0009057	161	0.064
positive regulation of gene expression	GO:0010628	290	0.064
ncrna processing	GO:0034470	30	0.050
positive regulation of transcription dna templated	GO:0045893	266	0.048
endocytosis	GO:0006897	310	0.047
reproductive system development	GO:0061458	74	0.045
gonad development	GO:0008406	50	0.042
response to organic substance	GO:0010033	284	0.042
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.040
cell motility	GO:0048870	251	0.037
regulation of cell cycle phase transition	GO:1901987	130	0.037
negative regulation of cellular metabolic process	GO:0031324	382	0.036
regulation of mitotic cell cycle	GO:0007346	190	0.034
cellular macromolecular complex assembly	GO:0034622	153	0.034
nuclear transcribed mrna catabolic process	GO:0000956	24	0.034
rna splicing	GO:0008380	83	0.034
phosphorylation	GO:0016310	294	0.033
dna metabolic process	GO:0006259	227	0.033
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.033
embryo development ending in birth or egg hatching	GO:0009792	152	0.032
organonitrogen compound metabolic process	GO:1901564	318	0.032
negative regulation of cell cycle process	GO:0010948	109	0.032
regulation of cell cycle	GO:0051726	291	0.031
carboxylic acid metabolic process	GO:0019752	92	0.031
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.030
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.030
protein modification process	GO:0036211	438	0.030
cellular response to chemical stimulus	GO:0070887	199	0.030
development of primary sexual characteristics	GO:0045137	50	0.029
positive regulation of macromolecule metabolic process	GO:0010604	405	0.029
positive regulation of signaling	GO:0023056	243	0.029
cellular protein modification process	GO:0006464	438	0.028
organic substance catabolic process	GO:1901575	308	0.028
actin filament based process	GO:0030029	220	0.027
negative regulation of cell cycle phase transition	GO:1901988	103	0.026
cellular macromolecule catabolic process	GO:0044265	136	0.026
mrna catabolic process	GO:0006402	33	0.026
sex differentiation	GO:0007548	81	0.026
rna catabolic process	GO:0006401	37	0.025
response to biotic stimulus	GO:0009607	294	0.024
regulation of mitotic cell cycle phase transition	GO:1901990	130	0.024
epithelial cell differentiation	GO:0030855	322	0.023
establishment of localization in cell	GO:0051649	402	0.023
protein transport	GO:0015031	155	0.023
regulation of cell cycle process	GO:0010564	181	0.023
reproductive structure development	GO:0048608	74	0.022
intracellular transport	GO:0046907	228	0.022
ribonucleoprotein complex assembly	GO:0022618	23	0.021
programmed cell death	GO:0012501	257	0.021
cellular catabolic process	GO:0044248	372	0.021
cellular response to organic substance	GO:0071310	132	0.021
actin cytoskeleton organization	GO:0030036	206	0.019
regulation of catalytic activity	GO:0050790	185	0.019
protein localization	GO:0008104	284	0.019
response to other organism	GO:0051707	293	0.019
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.018
establishment of organelle localization	GO:0051656	122	0.018
ribonucleoprotein complex subunit organization	GO:0071826	28	0.018
body morphogenesis	GO:0010171	2	0.018
localization of cell	GO:0051674	257	0.017
gland development	GO:0048732	191	0.017
developmental growth	GO:0048589	280	0.017
negative regulation of purine nucleotide catabolic process	GO:0033122	1	0.017
ribosome biogenesis	GO:0042254	8	0.017
transcription from rna polymerase ii promoter	GO:0006366	368	0.017
regulation of molecular function	GO:0065009	217	0.017
positive regulation of response to stimulus	GO:0048584	323	0.017
protein complex biogenesis	GO:0070271	201	0.016
oxoacid metabolic process	GO:0043436	103	0.016
cytoplasmic transport	GO:0016482	130	0.016
positive regulation of cell communication	GO:0010647	250	0.016
cellular macromolecule localization	GO:0070727	220	0.016
regulation of catabolic process	GO:0009894	170	0.016
organic acid metabolic process	GO:0006082	103	0.016
immune system process	GO:0002376	347	0.015
phagocytosis	GO:0006909	215	0.015
exocrine system development	GO:0035272	162	0.015
regulation of cell proliferation	GO:0042127	163	0.015
chromosome organization	GO:0051276	360	0.015
response to external biotic stimulus	GO:0043207	293	0.015
small molecule metabolic process	GO:0044281	305	0.015
positive regulation of signal transduction	GO:0009967	223	0.015
negative regulation of intrinsic apoptotic signaling pathway	GO:2001243	1	0.014
organelle localization	GO:0051640	148	0.014
morphogenesis of an epithelium	GO:0002009	276	0.014
death	GO:0016265	284	0.014
multi organism reproductive behavior	GO:0044705	121	0.014
cell cycle checkpoint	GO:0000075	95	0.014
negative regulation of rna metabolic process	GO:0051253	251	0.014
heterocycle catabolic process	GO:0046700	166	0.013
protein alkylation	GO:0008213	43	0.013
multi organism behavior	GO:0051705	175	0.013
reproductive behavior	GO:0019098	122	0.013
tissue morphogenesis	GO:0048729	297	0.013
establishment of protein localization	GO:0045184	163	0.013
negative regulation of multicellular organismal process	GO:0051241	142	0.013
negative regulation of cell cycle	GO:0045786	116	0.013
mrna splicing via spliceosome	GO:0000398	73	0.013
single organism intracellular transport	GO:1902582	207	0.013
regulation of immune system process	GO:0002682	176	0.013
cellular amino acid metabolic process	GO:0006520	61	0.012
cellular response to dna damage stimulus	GO:0006974	223	0.012
cell cycle phase transition	GO:0044770	140	0.012
striated muscle cell differentiation	GO:0051146	90	0.012
regulation of protein metabolic process	GO:0051246	256	0.012
mitotic cell cycle phase transition	GO:0044772	138	0.012
organonitrogen compound biosynthetic process	GO:1901566	117	0.011
negative regulation of protein metabolic process	GO:0051248	85	0.011
immune system development	GO:0002520	57	0.011
regulation of multicellular organismal development	GO:2000026	414	0.011
macromolecule methylation	GO:0043414	45	0.011
negative regulation of gene expression	GO:0010629	387	0.011
protein complex assembly	GO:0006461	200	0.011
histone modification	GO:0016570	106	0.011
fertilization	GO:0009566	26	0.011
autophagic cell death	GO:0048102	83	0.011
g2 dna damage checkpoint	GO:0031572	69	0.011
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.011
negative regulation of mitotic cell cycle	GO:0045930	109	0.011
mitotic dna integrity checkpoint	GO:0044774	75	0.010
cell proliferation	GO:0008283	299	0.010
base excision repair	GO:0006284	2	0.010
salivary gland development	GO:0007431	162	0.010
nuclear transport	GO:0051169	72	0.010
negative regulation of cellular biosynthetic process	GO:0031327	277	0.010
methylation	GO:0032259	47	0.010
positive regulation of chromatin modification	GO:1903310	17	0.010
receptor mediated endocytosis	GO:0006898	21	0.010

NHP2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org

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