Drosophila melanogaster

176 known processes

Atpalpha (Dmel_CG5670)

Na pump alpha subunit

(Aliases: Na+/K+ ATPase alpha subunit,Na+-K+-ATPase,l(3)j6A4,JY,K[+]-ATPase alpha-subunit,Na,Na/K-ATPase,Na-p,CG5670,Na[+],ATPa,dnATPase,ATPBagr,l(3)01453,l(3)01164,Na[+]/K[+] ATPase,Na/K-ATPase alpha-subunit,NaK,l(3)rM454,Da-47,K-ATPase,ATPalpha,NaK ATPase,Na[+]-K[+]-ATPase alpha[[5]]-subunit,Na[+]K[+]ATPase,K[+]-ATPase,l(3)04492,Na[+]/K[+]-ATPase,K[+] -ATPase,Atpa,K[+]-ATPase alpha subunit,Na[+]K[+] ATPase,l(3)j3B2,l(3)j3B7,l(3)ry136,Na[+]/K[+]ATPase,Dmel\CG5670,K ATPase,Atp a,sodium/potassium transporting ATPase alpha)

Atpalpha biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
muscle structure developmentGO:00610612241.000
Zebrafish
synaptic transmissionGO:00072682880.998
single organism behaviorGO:00447083910.997
regulation of tube architecture open tracheal systemGO:0035152680.996
respiratory system developmentGO:00605412130.995
tissue morphogenesisGO:00487292970.993
Zebrafish
embryo development ending in birth or egg hatchingGO:00097921520.990
cellular component assembly involved in morphogenesisGO:00109271510.984
cell cell junction assemblyGO:0007043380.982
cell motilityGO:00488702510.981
Zebrafish Mouse
growthGO:00400073590.978
actin filament based processGO:00300292200.977
Rat
open tracheal system developmentGO:00074242040.972
actin cytoskeleton organizationGO:00300362060.966
synapse organizationGO:00508081960.964
embryonic morphogenesisGO:00485982060.960
Zebrafish
adult locomotory behaviorGO:0008344760.954
locomotory behaviorGO:00076261760.951
cell deathGO:00082192790.950
striated muscle cell differentiationGO:0051146900.948
positive regulation of developmental processGO:00510941430.932
organelle localizationGO:00516401480.893
muscle cell differentiationGO:00426921030.867
neuromuscular synaptic transmissionGO:0007274670.867
regulation of multicellular organismal developmentGO:20000264140.867
regulation of cell differentiationGO:00455953020.857
cation transmembrane transportGO:0098655880.852
synapse assemblyGO:00074161430.844
myofibril assemblyGO:0030239360.841
larval developmentGO:00021641040.819
Worm
heart developmentGO:0007507820.808
Zebrafish
localization of cellGO:00516742570.800
Zebrafish Mouse
establishment of localization in cellGO:00516494020.794
regulation of cell developmentGO:00602842150.791
organelle assemblyGO:00709251980.776
response to mechanical stimulusGO:0009612280.767
regulation of tube size open tracheal systemGO:0035151430.760
ion transportGO:00068111450.754
striated muscle cell developmentGO:0055002500.750
gliogenesisGO:0042063800.746
response to abiotic stimulusGO:00096283410.735
head developmentGO:00603221350.733
Zebrafish
axonogenesisGO:00074092900.721
cation transportGO:00068121100.718
regulation of anatomical structure sizeGO:00900661630.689
agingGO:00075681430.687
organic substance transportGO:00717022570.676
branching involved in open tracheal system developmentGO:0060446450.673
establishment of organelle localizationGO:00516561220.670
positive regulation of cell deathGO:0010942690.662
regulation of neurotransmitter levelsGO:0001505380.660
Mouse
programmed cell deathGO:00125012570.648
multicellular organismal agingGO:00102591400.645
deathGO:00162652840.623
vesicle mediated transportGO:00161923810.610
oxoacid metabolic processGO:00434361030.594
endocytosisGO:00068973100.583
developmental growthGO:00485892800.582
adult behaviorGO:00305341370.566
circulatory system developmentGO:0072359820.564
Zebrafish
transmembrane transportGO:00550851390.538
synaptic vesicle transportGO:0048489500.535
cell growthGO:00160491080.529
spermatogenesisGO:00072832000.518
Mouse
tube developmentGO:00352952440.518
Zebrafish
striated muscle myosin thick filament assemblyGO:007168830.517
apical junction assemblyGO:0043297320.502
heart morphogenesisGO:0003007320.479
Zebrafish
regulation of neurogenesisGO:00507671580.472
protein catabolic processGO:00301631010.466
Worm
multicellular organismal reproductive behaviorGO:00330571100.463
single organism intracellular transportGO:19025822070.454
cellular response to organic substanceGO:00713101320.452
Human Mouse
central nervous system developmentGO:00074172010.451
Zebrafish
positive regulation of cellular component organizationGO:00511301560.449
developmental maturationGO:00217001720.445
cell divisionGO:00513012480.444
regulation of cell projection organizationGO:0031344920.431
forebrain developmentGO:003090020.426
intracellular transportGO:00469072280.419
single organism cellular localizationGO:19025801800.399
regulation of neuron projection developmentGO:0010975690.393
regulation of organelle organizationGO:00330431960.393
morphogenesis of an epitheliumGO:00020092760.390
Zebrafish
regulation of programmed cell deathGO:00430671520.388
cardiovascular system developmentGO:0072358820.386
Zebrafish
protein localizationGO:00081042840.385
cell junction assemblyGO:0034329420.376
regulation of nervous system developmentGO:00519602480.369
regulation of cellular component biogenesisGO:00440872010.366
cell maturationGO:00484691440.366
response to light stimulusGO:00094161240.359
Mouse
organic acid metabolic processGO:00060821030.356
neuromuscular junction developmentGO:00075281490.347
establishment of synaptic vesicle localizationGO:0097480500.346
synaptic vesicle recyclingGO:0036465280.342
neurological system processGO:00508773580.341
regulation of transportGO:00510491810.338
Mouse Rat
epithelial cell differentiationGO:00308553220.335
positive regulation of cell proliferationGO:0008284470.334
regulation of transmembrane transportGO:0034762270.333
mating behaviorGO:00076171060.331
cell migrationGO:00164772380.329
Zebrafish
ameboidal type cell migrationGO:00016671510.321
cell junction organizationGO:0034330570.321
regulation of localizationGO:00328792750.320
Mouse Rat
positive regulation of cell differentiationGO:0045597640.319
nucleobase containing small molecule metabolic processGO:00550861740.314
defense responseGO:00069523000.309
tube morphogenesisGO:00352391910.306
Zebrafish
actomyosin structure organizationGO:0031032560.301
cellular homeostasisGO:0019725800.289
Human Zebrafish Mouse
regulation of anatomical structure morphogenesisGO:00226032420.283
regulation of embryonic developmentGO:0045995680.281
glial cell differentiationGO:0010001350.277
developmental cell growthGO:0048588520.275
neuron projection guidanceGO:00974852410.260
spermatid developmentGO:0007286980.259
cellular response to chemical stimulusGO:00708871990.251
Human Mouse
regulation of synaptic transmissionGO:0050804690.248
cellular amino acid metabolic processGO:0006520610.244
spermatid differentiationGO:00485151140.244
secretion by cellGO:00329401010.237
regionalizationGO:00030024160.234
Zebrafish
regulation of molecular functionGO:00650092170.228
positive regulation of programmed cell deathGO:0043068620.226
organic substance catabolic processGO:19015753080.221
protein complex assemblyGO:00064612000.218
anatomical structure homeostasisGO:0060249970.209
muscle cell developmentGO:0055001500.209
generation of precursor metabolites and energyGO:0006091420.206
learning or memoryGO:00076111410.201
Mouse
cellular protein complex assemblyGO:0043623710.194
regulation of cell morphogenesisGO:00226041630.188
cellular respirationGO:0045333260.184
cell cell junction organizationGO:0045216550.180
neuron deathGO:0070997270.179
response to organic substanceGO:00100332840.175
Human Mouse
epidermis developmentGO:0008544650.172
epithelial tube morphogenesisGO:0060562880.171
Zebrafish
skeletal muscle organ developmentGO:0060538480.171
Zebrafish
positive regulation of apoptotic processGO:0043065470.164
lipid metabolic processGO:00066291210.163
Mouse
cell proliferationGO:00082832990.159
regulation of cellular protein metabolic processGO:00322682430.153
regulation of apoptotic processGO:00429811300.150
macromolecular complex assemblyGO:00650032560.148
receptor mediated endocytosisGO:0006898210.148
glycosyl compound metabolic processGO:19016571270.146
cellular protein localizationGO:00346131600.139
determination of adult lifespanGO:00083401370.138
regulation of cell cycle processGO:00105641810.137
developmental growth involved in morphogenesisGO:0060560650.134
neuron neuron synaptic transmissionGO:0007270140.133
apoptotic processGO:00069151590.133
carboxylic acid metabolic processGO:0019752920.129
catabolic processGO:00090564090.124
synaptic vesicle localizationGO:0097479530.123
somatic muscle developmentGO:0007525660.123
regulation of tube length open tracheal systemGO:0035159240.120
regulation of cellular response to stressGO:0080135890.118
regulation of protein metabolic processGO:00512462560.118
negative regulation of cell communicationGO:00106482230.111
organonitrogen compound metabolic processGO:19015643180.110
embryonic development via the syncytial blastodermGO:00017001480.109
negative regulation of signal transductionGO:00099682060.107
response to oxygen containing compoundGO:19017002000.107
Human Mouse
neurotransmitter secretionGO:0007269350.106
cell recognitionGO:00080371020.106
digestive system developmentGO:00551231490.105
exocytosisGO:0006887280.105
cognitionGO:00508901410.105
Mouse
sensory organ morphogenesisGO:00905962600.103
Zebrafish
glial cell developmentGO:0021782270.102
cell type specific apoptotic processGO:0097285380.097
ion transmembrane transportGO:00342201220.096
neurotransmitter transportGO:0006836370.094
Mouse
epithelial cell migration open tracheal systemGO:0007427320.094
embryonic organ developmentGO:0048568500.093
Zebrafish
energy derivation by oxidation of organic compoundsGO:0015980320.093
response to woundingGO:0009611940.092
imaginal disc derived appendage morphogenesisGO:00351143950.091
regulation of secretion by cellGO:1903530390.089
oxidation reduction processGO:00551141230.088
reproductive system developmentGO:0061458740.087
molting cycleGO:0042303560.085
action potentialGO:0001508130.084
Worm
secretionGO:00469031090.084
appendage morphogenesisGO:00351073970.084
taxisGO:00423303040.083
Zebrafish
purine ribonucleoside monophosphate metabolic processGO:0009167500.083
regulation of cellular localizationGO:00603411360.082
organophosphate metabolic processGO:00196371950.079
response to external biotic stimulusGO:00432072930.079
negative regulation of response to stimulusGO:00485852580.079
intercellular transportGO:001049620.078
apoptotic signaling pathwayGO:0097190270.077
macromolecule catabolic processGO:00090571610.075
Worm
purine nucleoside biosynthetic processGO:004245130.074
reproductive structure developmentGO:0048608740.074
axon guidanceGO:00074112330.074
regulation of ion transportGO:0043269390.073
Mouse Rat
nuclear divisionGO:00002803320.072
eye developmentGO:00016543230.072
regulation of phosphatase activityGO:001092130.071
response to oxidative stressGO:0006979860.070
establishment of protein localizationGO:00451841630.070
cellular catabolic processGO:00442483720.068
vesicle localizationGO:0051648550.067
regulation of cell deathGO:00109411730.067
positive regulation of cellular component biogenesisGO:0044089800.066
extracellular structure organizationGO:0043062460.066
Zebrafish
axonal fasciculationGO:0007413120.066
metal ion transportGO:0030001740.065
regulation of protein polymerizationGO:0032271280.064
establishment of tissue polarityGO:0007164870.064
response to endogenous stimulusGO:00097191190.064
Human Mouse
positive regulation of multicellular organismal processGO:00512401430.063
Mouse
cellular protein modification processGO:00064644380.063
signal releaseGO:0023061490.063
cellular macromolecular complex assemblyGO:00346221530.060
neuronal action potentialGO:0019228100.060
positive regulation of transportGO:0051050920.060
regulation of cell morphogenesis involved in differentiationGO:0010769610.060
gonad developmentGO:0008406500.059
epidermal cell differentiationGO:0009913510.059
protein complex biogenesisGO:00702712010.059
anion transportGO:0006820410.058
synaptic vesicle fusion to presynaptic membraneGO:003162970.058
single organism biosynthetic processGO:00447112060.058
Mouse
regulation of growthGO:00400082330.057
negative regulation of cell differentiationGO:00455961430.057
response to temperature stimulusGO:00092661060.056
regulation of secretionGO:0051046440.055
regulation of protein complex assemblyGO:0043254420.055
protein transportGO:00150311550.055
organic cyclic compound catabolic processGO:19013611680.054
extracellular matrix organizationGO:0030198320.054
Zebrafish
actin filament polymerizationGO:0030041270.054
regulation of transmembrane transporter activityGO:002289860.054
immune system processGO:00023763470.053
synaptic vesicle endocytosisGO:0048488280.052
small molecule metabolic processGO:00442813050.052
body morphogenesisGO:001017120.051
Zebrafish
cellular macromolecule localizationGO:00707272200.051
sensory perceptionGO:00076001960.050
morphogenesis of a branching epitheliumGO:0061138450.050
matingGO:00076181200.050
juvenile hormone mediated signaling pathwayGO:003562630.049
purine ribonucleoside metabolic processGO:00461281270.049
organelle fissionGO:00482853400.048
rhythmic behaviorGO:0007622760.048
digestive tract morphogenesisGO:00485461270.047
response to biotic stimulusGO:00096072940.045
response to growth factorGO:0070848310.045
neuron projection extensionGO:1990138320.044
reproductive behaviorGO:00190981220.044
regulation of rac gtpase activityGO:003231410.043
muscle organ developmentGO:00075171270.043
Zebrafish
regulation of membrane potentialGO:0042391350.043
Human Mouse Rat Worm
male gamete generationGO:00482322010.043
Mouse
blastoderm segmentationGO:00073501590.042
protein polymerizationGO:0051258420.042
post embryonic appendage morphogenesisGO:00351203850.042
dendrite developmentGO:00163582040.040
negative regulation of intrinsic apoptotic signaling pathwayGO:200124310.039
regulation of apoptotic signaling pathwayGO:2001233100.039
wound healingGO:0042060750.039
muscle attachmentGO:0016203360.039
eye morphogenesisGO:00485922600.038
carbohydrate metabolic processGO:0005975820.038
ribonucleoside monophosphate metabolic processGO:0009161510.037
biological adhesionGO:00226101380.037
germarium derived egg chamber formationGO:00072931010.036
retina development in camera type eyeGO:006004140.036
ribose phosphate metabolic processGO:00196931450.036
response to heatGO:0009408630.036
neural precursor cell proliferationGO:0061351750.034
epithelial cell developmentGO:00020642740.032
sleepGO:0030431490.032
brain developmentGO:00074201200.032
Zebrafish
learningGO:0007612750.032
Mouse
positive regulation of signal transductionGO:00099672230.031
establishment of blood brain barrierGO:0060856160.031
circadian rhythmGO:00076231050.031
regulation of protein phosphorylationGO:0001932640.031
purine ribonucleotide catabolic processGO:00091541090.031
embryonic pattern specificationGO:00098801740.030
regulation of actin polymerization or depolymerizationGO:0008064270.030
cellular response to endogenous stimulusGO:0071495800.030
Human Mouse
sex differentiationGO:0007548810.030
neuroblast proliferationGO:0007405740.030
regulation of cell cycleGO:00517262910.030
olfactory learningGO:0008355560.029
regulation of synapse structure and activityGO:00508031280.028
heart processGO:0003015370.028
Zebrafish Mouse Rat
compound eye developmentGO:00487493070.028
myosin filament assemblyGO:003103450.027
appendage developmentGO:00487364010.027
histone h3 k9 modificationGO:0061647120.027
regulation of multi organism processGO:00439001310.027
negative regulation of programmed cell deathGO:0043069720.027
epithelial cell migrationGO:00106311480.026
histone h3 s10 phosphorylationGO:004398720.026
eggshell formationGO:00307031050.026
negative regulation of phosphatase activityGO:001092330.026
homeostatic processGO:00425921990.026
meiotic nuclear envelope disassemblyGO:005107820.026
positive regulation of growthGO:0045927750.025
response to starvationGO:0042594970.025
detection of light stimulus involved in sensory perceptionGO:005096290.025
positive regulation of macromolecule metabolic processGO:00106044050.025
imaginal disc derived appendage developmentGO:00487373990.025
septate junction assemblyGO:0019991260.024
axon extensionGO:0048675320.024
positive regulation of nucleobase containing compound metabolic processGO:00459353320.024
enzyme linked receptor protein signaling pathwayGO:00071671790.024
response to alcoholGO:0097305950.023
positive regulation of cell developmentGO:0010720610.023
male mating behaviorGO:0060179700.023
nucleocytoplasmic transportGO:0006913720.022
columnar cuboidal epithelial cell developmentGO:00020662490.022
response to radiationGO:00093141550.022
Mouse
regulation of ion transmembrane transportGO:0034765270.022
regulation of neuron differentiationGO:00456641030.022
regulation of cell substrate adhesionGO:001081020.022
detection of light stimulusGO:0009583580.022
cell proliferation involved in compound eye morphogenesisGO:003573640.022
cell projection assemblyGO:0030031940.021
purine nucleoside triphosphate metabolic processGO:00091441190.021
camera type eye developmentGO:004301040.020
protein phosphorylationGO:00064681690.020
carbohydrate derivative catabolic processGO:19011361180.020
phagocytosisGO:00069092150.020
dendrite morphogenesisGO:00488131990.020
negative regulation of intrinsic apoptotic signaling pathway by p53 class mediatorGO:190225410.020
ribonucleoside triphosphate catabolic processGO:00092031080.020
positive regulation of secretionGO:0051047220.019
positive regulation of neurotransmitter secretionGO:000195620.019
negative regulation of mitotic anaphase promoting complex activityGO:006056420.019
cellular response to oxidative stressGO:0034599280.019
morphogenesis of a branching structureGO:0001763450.019
oocyte maturationGO:000155630.018
cytoplasmic transportGO:00164821300.018
ribonucleoside triphosphate biosynthetic processGO:000920120.018
digestive tract developmentGO:00485651490.018
embryonic axis specificationGO:00005781070.018
negative regulation of apoptotic processGO:0043066630.018
inorganic cation transmembrane transportGO:0098662610.018
proteolysisGO:00065081920.017
multicellular organismal signalingGO:0035637120.017
tissue migrationGO:00901301550.017
immune responseGO:00069552460.017
dorsal appendage formationGO:0046843470.017
skin developmentGO:0043588650.017
establishment of vesicle localizationGO:0051650510.017
negative regulation of cellular metabolic processGO:00313243820.017
Mouse
nuclear transportGO:0051169720.017
organonitrogen compound catabolic processGO:19015651280.017
phospholipid transportGO:001591420.017
regulation of necrotic cell deathGO:001093910.017
chemotaxisGO:00069352490.016
development of primary sexual characteristicsGO:0045137500.016
rna processingGO:00063961470.016
mitotic spindle organizationGO:00070522200.016
regulation of neurotransmitter secretionGO:0046928140.016
protein destabilizationGO:003164820.016
positive regulation of signalingGO:00230562430.016
positive regulation of protein complex assemblyGO:0031334220.016
cytokinesisGO:0000910900.016
regulation of phosphate metabolic processGO:00192202100.016
cellular response to nutrientGO:003167010.016
glycosyl compound catabolic processGO:19016581120.015
negative regulation of signalingGO:00230572190.015
nucleobase containing compound catabolic processGO:00346551650.015
regulation of microtubule cytoskeleton organizationGO:0070507410.015
stem cell proliferationGO:0072089880.015
circulatory system processGO:0003013370.015
Zebrafish Mouse Rat
monocarboxylic acid metabolic processGO:0032787290.015
stem cell differentiationGO:00488631170.015
axon ensheathmentGO:0008366100.014
regulation of mapk cascadeGO:0043408920.014
atp metabolic processGO:0046034490.014
purine containing compound catabolic processGO:00725231120.014
chorion containing eggshell formationGO:00073041050.014
negative regulation of organelle organizationGO:0010639560.014
regulation of cell proliferationGO:00421271630.014
nucleoside monophosphate metabolic processGO:0009123520.014
positive regulation of chromatin silencing at telomereGO:003194020.014
positive regulation of phosphorylationGO:0042327870.014
chromosome segregationGO:00070591570.014
multi organism reproductive behaviorGO:00447051210.014
neuron recognitionGO:00080381010.013
embryonic heart tube developmentGO:0035050220.013
Zebrafish
positive regulation of lipid catabolic processGO:005099610.013
regulation of chromosome organizationGO:0033044640.013
regulation of hemocyte proliferationGO:0035206370.013
negative regulation of signal transduction by p53 class mediatorGO:190179710.013
nucleoside phosphate metabolic processGO:00067531620.013
positive regulation of cellular protein metabolic processGO:00322701180.012
monovalent inorganic cation transportGO:0015672400.012
regulation of response to stressGO:00801342000.012
cleavage furrow formationGO:003608920.012
protein targetingGO:0006605640.012
cellular response to oxygen containing compoundGO:1901701790.012
actin filament organizationGO:00070151260.012
histone h3 k36 methylationGO:001045210.012
muscle tissue developmentGO:0060537300.012
Zebrafish
germarium derived female germ line cyst formationGO:0030727420.012
response to organic cyclic compoundGO:0014070890.012
Human Mouse
positive regulation of molecular functionGO:00440931360.012
regulation of actin filament based processGO:0032970420.012
Rat
regulation of short term neuronal synaptic plasticityGO:004817250.012
lateral inhibitionGO:00463312060.011
actin polymerization or depolymerizationGO:0008154310.011
ribonucleoside metabolic processGO:00091191270.011
chromosome organizationGO:00512763600.011
negative regulation of gtpase activityGO:003426010.011
peptidyl arginine omega n methylationGO:003524740.011
negative regulation of sister chromatid cohesionGO:004587510.011
transmission of nerve impulseGO:0019226120.011
phosphorylationGO:00163102940.011
regulation of neuron apoptotic processGO:0043523160.011
rna localizationGO:00064031150.011
neurotransmitter receptor metabolic processGO:004521330.011
regulation of developmental growthGO:00486381740.011
segmentationGO:00352822070.011
negative regulation of nitrogen compound metabolic processGO:00511722650.011
nucleobase containing compound transportGO:0015931560.011
maintenance of locationGO:0051235730.011
female germ line cyst formationGO:0048135420.011
synaptic transmission gabaergicGO:005193210.010
positive regulation of macromolecule biosynthetic processGO:00105572830.010
regulation of actin cytoskeleton organizationGO:0032956420.010
purine nucleoside catabolic processGO:00061521120.010
dendritic spine developmentGO:006099640.010
protein modification by small protein conjugation or removalGO:00706471060.010
heterocycle catabolic processGO:00467001660.010
mitochondrion organizationGO:0007005650.010
negative regulation of rna metabolic processGO:00512532510.010
establishment of planar polarityGO:0001736870.010
asymmetric neuroblast division resulting in ganglion mother cell formationGO:005506020.010
wing disc morphogenesisGO:00074723440.010
positive regulation of histone modificationGO:0031058120.010
response to nitrogen compoundGO:1901698900.010
purine nucleoside monophosphate metabolic processGO:0009126500.010
meiotic nuclear divisionGO:00071261510.010
nucleoside metabolic processGO:00091161270.010

Atpalpha disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.094
musculoskeletal system diseaseDOID:1700.094
cancerDOID:16200.035
meningiomaDOID:356500.035
nervous system cancerDOID:309300.035
familial meningiomaDOID:458600.035
disease of cellular proliferationDOID:1456600.035
central nervous system cancerDOID:362000.035
organ system cancerDOID:005068600.035
benign neoplasmDOID:006007200.021
connective tissue diseaseDOID:6500.019
bone diseaseDOID:008000100.017
chromosomal diseaseDOID:008001400.015