IMP: Integrative Multi-species Prediction

Drosophila melanogaster

0 known processes

Dek (Dmel_CG5935)

CG5935 gene product from transcript CG5935-RA

(Aliases: Dmel\CG5935,anon-WO0172774.192,EG:EG0003.6,l(2)k09907,CG5935,anon-WO0172774.191,DEK,anon-WO0172774.194,l(2)04154,dDEK,CG593)

Entrez: 47906
FLYBASE: FBgn0026533
UniProtKB: Q8T0D3
UniProtKB: Q8IFW6
UniProtKB: A1ZAK3
UniProtKB: A1ZAK4

Process Predictions
Disease Predictions

Dek biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
negative regulation of transcription dna templated	GO:0045892	237	0.785
positive regulation of rna biosynthetic process	GO:1902680	266	0.393
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.385
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.361
dna metabolic process	GO:0006259	227	0.329
negative regulation of cellular biosynthetic process	GO:0031327	277	0.231
regulation of chromatin silencing	GO:0031935	36	0.216
negative regulation of biosynthetic process	GO:0009890	277	0.206
regulation of mitotic cell cycle	GO:0007346	190	0.192
cell proliferation	GO:0008283	299	0.189
mrna metabolic process	GO:0016071	124	0.188
positive regulation of transcription dna templated	GO:0045893	266	0.186
negative regulation of rna biosynthetic process	GO:1902679	240	0.180
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.164
nuclear division	GO:0000280	332	0.148
cellular response to dna damage stimulus	GO:0006974	223	0.136
catabolic process	GO:0009056	409	0.136
gene silencing	GO:0016458	138	0.129
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.127
cellular catabolic process	GO:0044248	372	0.122
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.120
regulation of gene expression epigenetic	GO:0040029	128	0.113
regulation of cell cycle	GO:0051726	291	0.110
regulation of protein metabolic process	GO:0051246	256	0.102
photoreceptor cell differentiation	GO:0046530	170	0.098
mrna processing	GO:0006397	104	0.085
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.082
organelle fission	GO:0048285	340	0.080
chromatin silencing	GO:0006342	76	0.079
dna integrity checkpoint	GO:0031570	81	0.077
mitotic nuclear division	GO:0007067	213	0.069
negative regulation of gene expression epigenetic	GO:0045814	77	0.067
dendrite development	GO:0016358	204	0.066
aging	GO:0007568	143	0.065
cellular protein modification process	GO:0006464	438	0.065
regulation of cell death	GO:0010941	173	0.065
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.064
cell cycle checkpoint	GO:0000075	95	0.063
negative regulation of rna metabolic process	GO:0051253	251	0.060
spindle organization	GO:0007051	253	0.057
negative regulation of gene expression	GO:0010629	387	0.056
regulation of cellular protein metabolic process	GO:0032268	243	0.055
chromatin remodeling	GO:0006338	72	0.055
negative regulation of cellular protein metabolic process	GO:0032269	85	0.055
positive regulation of macromolecule metabolic process	GO:0010604	405	0.052
regulation of apoptotic process	GO:0042981	130	0.052
multicellular organismal aging	GO:0010259	140	0.052
rna splicing via transesterification reactions with bulged adenosine as nucleophile	GO:0000377	73	0.050
mitotic cell cycle checkpoint	GO:0007093	88	0.049
regulation of gene silencing	GO:0060968	63	0.047
regulation of cell cycle phase transition	GO:1901987	130	0.046
covalent chromatin modification	GO:0016569	106	0.046
chromosome organization	GO:0051276	360	0.043
positive regulation of rna metabolic process	GO:0051254	271	0.043
histone modification	GO:0016570	106	0.043
nucleus organization	GO:0006997	45	0.040
regulation of phosphate metabolic process	GO:0019220	210	0.039
response to oxygen containing compound	GO:1901700	200	0.039
positive regulation of phosphate metabolic process	GO:0045937	139	0.038
cell cycle phase transition	GO:0044770	140	0.037
regulation of transcription by chromatin organization	GO:0034401	3	0.036
compound eye development	GO:0048749	307	0.036
organ growth	GO:0035265	56	0.035
heterocycle catabolic process	GO:0046700	166	0.035
dna damage checkpoint	GO:0000077	78	0.035
regulation of cell cycle process	GO:0010564	181	0.034
neurological system process	GO:0050877	358	0.033
regulation of phosphorus metabolic process	GO:0051174	210	0.033
organonitrogen compound metabolic process	GO:1901564	318	0.033
positive regulation of gene expression	GO:0010628	290	0.033
mitotic dna integrity checkpoint	GO:0044774	75	0.032
protein complex assembly	GO:0006461	200	0.031
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	119	0.031
rhythmic process	GO:0048511	106	0.031
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.030
chromatin modification	GO:0016568	147	0.030
eye development	GO:0001654	323	0.030
protein modification process	GO:0036211	438	0.030
compound eye photoreceptor cell differentiation	GO:0001751	140	0.030
embryo development ending in birth or egg hatching	GO:0009792	152	0.030
multi organism behavior	GO:0051705	175	0.028
regulation of cell proliferation	GO:0042127	163	0.028
mitotic spindle organization	GO:0007052	220	0.028
negative regulation of translation	GO:0017148	28	0.028
response to organic substance	GO:0010033	284	0.028
alternative mrna splicing via spliceosome	GO:0000380	60	0.028
cellular nitrogen compound catabolic process	GO:0044270	165	0.027
positive regulation of response to stimulus	GO:0048584	323	0.027
small gtpase mediated signal transduction	GO:0007264	88	0.027
growth	GO:0040007	359	0.027
regulation of rna splicing	GO:0043484	69	0.027
g2 dna damage checkpoint	GO:0031572	69	0.027
mitotic g2 dna damage checkpoint	GO:0007095	69	0.026
organic substance catabolic process	GO:1901575	308	0.025
positive regulation of multicellular organism growth	GO:0040018	21	0.025
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.025
immune system process	GO:0002376	347	0.025
meiotic nuclear division	GO:0007126	151	0.025
meiosis i	GO:0007127	59	0.025
negative regulation of mitotic cell cycle phase transition	GO:1901991	103	0.024
intracellular receptor signaling pathway	GO:0030522	19	0.023
nucleobase containing compound catabolic process	GO:0034655	165	0.023
negative regulation of cellular metabolic process	GO:0031324	382	0.023
dna conformation change	GO:0071103	105	0.022
chromatin assembly or disassembly	GO:0006333	52	0.022
positive regulation of mapk cascade	GO:0043410	63	0.022
ras protein signal transduction	GO:0007265	88	0.021
rna processing	GO:0006396	147	0.021
transcription from rna polymerase ii promoter	GO:0006366	368	0.021
ovarian follicle cell cell adhesion	GO:0007299	4	0.021
sensory organ morphogenesis	GO:0090596	260	0.021
positive regulation of epidermal growth factor activated receptor activity	GO:0045741	1	0.021
posttranscriptional regulation of gene expression	GO:0010608	145	0.021
meiotic cell cycle	GO:0051321	171	0.020
chromatin organization	GO:0006325	207	0.020
cellular macromolecule catabolic process	GO:0044265	136	0.020
nucleotide metabolic process	GO:0009117	161	0.020
methylation	GO:0032259	47	0.019
macromolecule catabolic process	GO:0009057	161	0.019
translation	GO:0006412	69	0.019
death	GO:0016265	284	0.019
formation of a compartment boundary	GO:0060288	4	0.019
posttranscriptional gene silencing	GO:0016441	46	0.018
single organism membrane organization	GO:0044802	93	0.018
dendrite morphogenesis	GO:0048813	199	0.018
small molecule metabolic process	GO:0044281	305	0.018
cell death	GO:0008219	279	0.018
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.018
eye morphogenesis	GO:0048592	260	0.018
regulation of programmed cell death	GO:0043067	152	0.018
multi organism reproductive behavior	GO:0044705	121	0.018
organic cyclic compound catabolic process	GO:1901361	168	0.018
histone lysine demethylation	GO:0070076	6	0.018
organophosphate metabolic process	GO:0019637	195	0.017
regulation of mrna processing	GO:0050684	71	0.017
atp dependent chromatin remodeling	GO:0043044	22	0.017
aromatic compound catabolic process	GO:0019439	166	0.017
cleavage furrow formation	GO:0036089	2	0.017
regulation of phosphorylation	GO:0042325	147	0.017
developmental growth	GO:0048589	280	0.016
nuclear pore organization	GO:0006999	1	0.016
regulation of mitotic cell cycle phase transition	GO:1901990	130	0.016
regulation of cellular component biogenesis	GO:0044087	201	0.016
fatty acid derivative biosynthetic process	GO:1901570	1	0.016
intracellular signal transduction	GO:0035556	300	0.016
regulation of developmental growth	GO:0048638	174	0.015
eye photoreceptor cell differentiation	GO:0001754	145	0.015
nucleosome organization	GO:0034728	59	0.015
positive regulation of biosynthetic process	GO:0009891	316	0.015
spermatogenesis	GO:0007283	200	0.015
intracellular transport	GO:0046907	228	0.015
positive regulation of cellular component biogenesis	GO:0044089	80	0.015
negative regulation of protein metabolic process	GO:0051248	85	0.014
mitotic cell cycle phase transition	GO:0044772	138	0.014
response to external biotic stimulus	GO:0043207	293	0.014
positive regulation of signal transduction	GO:0009967	223	0.014
protein transport	GO:0015031	155	0.014
negative regulation of intrinsic apoptotic signaling pathway	GO:2001243	1	0.013
response to alcohol	GO:0097305	95	0.013
regulation of alternative mrna splicing via spliceosome	GO:0000381	60	0.013
positive regulation of catalytic activity	GO:0043085	118	0.013
imaginal disc growth	GO:0007446	37	0.013
negative regulation of cell cycle phase transition	GO:1901988	103	0.013
cellular macromolecular complex assembly	GO:0034622	153	0.013
establishment of protein localization	GO:0045184	163	0.013
regulation of response to stress	GO:0080134	200	0.013
cellular protein catabolic process	GO:0044257	83	0.013
cell adhesion	GO:0007155	136	0.013
mitochondrial membrane organization	GO:0007006	3	0.012
regulation of mrna metabolic process	GO:1903311	72	0.012
protein import	GO:0017038	55	0.012
positive regulation of phosphorus metabolic process	GO:0010562	139	0.012
rhythmic behavior	GO:0007622	76	0.012
adult behavior	GO:0030534	137	0.012
positive regulation of signaling	GO:0023056	243	0.012
nucleobase containing small molecule metabolic process	GO:0055086	174	0.012
apoptotic process	GO:0006915	159	0.012
positive regulation of cellular biosynthetic process	GO:0031328	316	0.012
programmed cell death	GO:0012501	257	0.012
memory	GO:0007613	94	0.012
glycosyl compound catabolic process	GO:1901658	112	0.012
protein localization	GO:0008104	284	0.011
morphogenesis of an epithelium	GO:0002009	276	0.011
response to biotic stimulus	GO:0009607	294	0.011
rna splicing	GO:0008380	83	0.011
regulation of mrna splicing via spliceosome	GO:0048024	64	0.011
circadian rhythm	GO:0007623	105	0.011
amide biosynthetic process	GO:0043604	42	0.011
negative regulation of phosphatase activity	GO:0010923	3	0.011
positive regulation of cell communication	GO:0010647	250	0.011
macromolecular complex assembly	GO:0065003	256	0.011
humoral immune response	GO:0006959	117	0.011
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.010
positive regulation of cellular component organization	GO:0051130	156	0.010
male gamete generation	GO:0048232	201	0.010
body morphogenesis	GO:0010171	2	0.010
positive regulation of hydrolase activity	GO:0051345	78	0.010
regulation of protein modification process	GO:0031399	112	0.010

Dek disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org

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