Drosophila melanogaster

67 known processes

Top1 (Dmel_CG6146)

Topoisomerase 1

(Aliases: CG6146,topo I,Dmel\CG6146,l(1)G0229,TOP1,dTopoI,TopoI,top1,TopI,topoI,l(1)G0134,Topo I,l(1)top1,l(1)G0201,l(1)G0278)

Top1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
growthGO:00400073590.945
cellular protein modification processGO:00064644380.852
developmental growthGO:00485892800.760
multicellular organismal agingGO:00102591400.737
Worm
cellular catabolic processGO:00442483720.667
cell cycle phase transitionGO:00447701400.648
chromosome organizationGO:00512763600.641
oocyte microtubule cytoskeleton organizationGO:0016325350.624
regulation of cell cycle phase transitionGO:19019871300.583
protein modification processGO:00362114380.578
regulation of mitotic cell cycleGO:00073461900.551
mitotic spindle organizationGO:00070522200.532
cytoplasmic transportGO:00164821300.518
dna packagingGO:0006323910.508
deathGO:00162652840.503
organic substance catabolic processGO:19015753080.502
lateral inhibitionGO:00463312060.501
regulation of mitotic cell cycle phase transitionGO:19019901300.478
protein modification by small protein conjugation or removalGO:00706471060.465
programmed cell deathGO:00125012570.454
catabolic processGO:00090564090.453
cell proliferationGO:00082832990.448
epithelial cell differentiationGO:00308553220.437
nucleobase containing compound catabolic processGO:00346551650.436
histone modificationGO:00165701060.405
cellular macromolecule catabolic processGO:00442651360.392
regulation of vesicle mediated transportGO:0060627590.392
positive regulation of developmental processGO:00510941430.381
single organism biosynthetic processGO:00447112060.373
regulation of chromosome organizationGO:0033044640.373
protein ubiquitinationGO:0016567700.363
macromolecule catabolic processGO:00090571610.361
morphogenesis of follicular epitheliumGO:0016333360.358
dna metabolic processGO:00062592270.356
regulation of cell cycleGO:00517262910.355
agingGO:00075681430.350
Worm
blastoderm segmentationGO:00073501590.347
negative regulation of mitotic cell cycleGO:00459301090.344
regulation of multicellular organismal developmentGO:20000264140.344
dna integrity checkpointGO:0031570810.329
aromatic compound catabolic processGO:00194391660.326
establishment of localization in cellGO:00516494020.311
regulation of growthGO:00400082330.307
regulation of cellular protein metabolic processGO:00322682430.288
modification dependent macromolecule catabolic processGO:0043632790.287
chromatin modificationGO:00165681470.287
Human
positive regulation of macromolecule biosynthetic processGO:00105572830.282
regulation of protein metabolic processGO:00512462560.281
heterocycle catabolic processGO:00467001660.275
germarium derived egg chamber formationGO:00072931010.275
proteolysis involved in cellular protein catabolic processGO:0051603830.265
covalent chromatin modificationGO:00165691060.263
intracellular transportGO:00469072280.263
positive regulation of biosynthetic processGO:00098913160.260
response to abiotic stimulusGO:00096283410.251
oocyte constructionGO:00073081120.249
positive regulation of gene expressionGO:00106282900.247
ubiquitin dependent protein catabolic processGO:0006511780.246
spindle organizationGO:00070512530.244
negative regulation of cell communicationGO:00106482230.234
regulation of catabolic processGO:00098941700.230
protein targetingGO:0006605640.229
embryonic pattern specificationGO:00098801740.225
positive regulation of catabolic processGO:00098961050.213
regulation of proteasomal protein catabolic processGO:0061136390.212
protein transportGO:00150311550.210
positive regulation of cellular catabolic processGO:0031331950.200
positive regulation of multicellular organismal processGO:00512401430.198
positive regulation of rna biosynthetic processGO:19026802660.197
body morphogenesisGO:001017120.197
Worm
chromosome condensationGO:0030261410.193
proteasomal protein catabolic processGO:0010498590.192
positive regulation of rna metabolic processGO:00512542710.188
organic cyclic compound catabolic processGO:19013611680.188
single organism cellular localizationGO:19025801800.187
cell deathGO:00082192790.182
negative regulation of developmental processGO:00510932010.177
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434370.177
regulation of cell proliferationGO:00421271630.172
protein modification by small protein conjugationGO:0032446790.170
regulation of cellular component biogenesisGO:00440872010.166
modification dependent protein catabolic processGO:0019941780.165
negative regulation of cellular metabolic processGO:00313243820.165
mitotic cell cycle checkpointGO:0007093880.161
tube developmentGO:00352952440.160
proteolysisGO:00065081920.158
vesicle mediated transportGO:00161923810.155
Worm
organelle fissionGO:00482853400.153
Worm
single organism behaviorGO:00447083910.153
nucleobase containing small molecule metabolic processGO:00550861740.147
cellular response to chemical stimulusGO:00708871990.146
positive regulation of growthGO:0045927750.146
regulation of localizationGO:00328792750.146
cellular nitrogen compound catabolic processGO:00442701650.145
determination of adult lifespanGO:00083401370.143
Worm
organic substance transportGO:00717022570.141
organonitrogen compound metabolic processGO:19015643180.141
translationGO:0006412690.139
positive regulation of response to stimulusGO:00485843230.137
gonad developmentGO:0008406500.136
Worm
germ line stem cell divisionGO:0042078250.133
cellular macromolecular complex assemblyGO:00346221530.129
nucleocytoplasmic transportGO:0006913720.129
positive regulation of protein metabolic processGO:00512471280.126
dna damage checkpointGO:0000077780.125
purine nucleoside triphosphate catabolic processGO:00091461080.124
regulation of cellular catabolic processGO:00313291570.123
positive regulation of cellular protein metabolic processGO:00322701180.122
regulation of intracellular protein transportGO:0033157460.120
positive regulation of protein catabolic processGO:0045732340.120
positive regulation of cell proliferationGO:0008284470.120
dorsal ventral axis specification ovarian follicular epitheliumGO:0008069130.119
ribose phosphate metabolic processGO:00196931450.118
cell cell signaling involved in cell fate commitmentGO:00451682100.117
negative regulation of signal transductionGO:00099682060.115
establishment or maintenance of cytoskeleton polarityGO:0030952440.115
purine nucleoside metabolic processGO:00422781270.114
digestive tract developmentGO:00485651490.114
wing disc morphogenesisGO:00074723440.113
chemical homeostasisGO:0048878920.112
positive regulation of signal transductionGO:00099672230.112
developmental programmed cell deathGO:00106231380.112
multicellular organism growthGO:0035264460.111
negative regulation of cellular protein metabolic processGO:0032269850.111
response to sterolGO:0036314340.110
regulation of molecular functionGO:00650092170.109
single organism intracellular transportGO:19025822070.108
regulation of developmental growthGO:00486381740.106
gland morphogenesisGO:00226121450.105
regulation of phosphorus metabolic processGO:00511742100.104
appendage morphogenesisGO:00351073970.103
hemocyte differentiationGO:0042386380.103
response to oxygen containing compoundGO:19017002000.102
germarium derived oocyte fate determinationGO:0007294260.102
positive regulation of macromolecule metabolic processGO:00106044050.102
nucleoside phosphate metabolic processGO:00067531620.102
cellular macromolecule localizationGO:00707272200.102
actin filament based processGO:00300292200.101
dorsal ventral pattern formationGO:00099531330.099
sex differentiationGO:0007548810.095
Worm
negative regulation of multicellular organismal processGO:00512411420.094
cellular response to dna damage stimulusGO:00069742230.093
molting cycle chitin based cuticleGO:0007591560.092
epidermal cell differentiationGO:0009913510.090
endocytosisGO:00068973100.089
Worm
carbohydrate derivative catabolic processGO:19011361180.089
actin cytoskeleton organizationGO:00300362060.088
intracellular protein transportGO:00068861040.088
phosphorylationGO:00163102940.088
dorsal ventral axis specificationGO:0009950660.087
rhythmic processGO:00485111060.085
Human
positive regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032436190.085
response to radiationGO:00093141550.085
spermatid differentiationGO:00485151140.084
nucleotide metabolic processGO:00091171610.083
regulation of cellular protein catabolic processGO:1903362440.083
immune system processGO:00023763470.083
salivary gland developmentGO:00074311620.081
cellularizationGO:0007349900.081
regulation of phosphorylationGO:00423251470.081
digestive tract morphogenesisGO:00485461270.081
axis specificationGO:00097981670.080
regulation of proteolysis involved in cellular protein catabolic processGO:1903050440.080
cell cycle checkpointGO:0000075950.079
compound eye developmentGO:00487493070.079
establishment of mitochondrion localizationGO:005165470.078
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161540.078
reproductive structure developmentGO:0048608740.078
Worm
regulation of cell differentiationGO:00455953020.078
photoreceptor cell differentiationGO:00465301700.077
cellular protein catabolic processGO:0044257830.077
cell cycle dna replicationGO:0044786230.077
regulation of transcription from rna polymerase ii promoterGO:00063573780.077
mitotic cell cycle phase transitionGO:00447721380.076
cellular lipid metabolic processGO:0044255830.076
negative regulation of cell cycle phase transitionGO:19019881030.076
response to oxygen levelsGO:0070482590.075
ovarian follicle cell developmentGO:00307072480.075
regulation of immune responseGO:00507761180.075
appendage developmentGO:00487364010.074
morphogenesis of an epitheliumGO:00020092760.072
cytoskeleton dependent intracellular transportGO:0030705440.072
organ growthGO:0035265560.071
dorsal appendage formationGO:0046843470.071
regulation of hydrolase activityGO:0051336970.071
protein localization to organelleGO:0033365820.071
cell fate determinationGO:0001709910.070
positive regulation of mitotic cell cycleGO:0045931340.070
negative regulation of protein metabolic processGO:0051248850.070
organophosphate metabolic processGO:00196371950.070
compound eye morphogenesisGO:00017452490.070
chromatin organizationGO:00063252070.069
Human
spermatogenesisGO:00072832000.068
negative regulation of cell differentiationGO:00455961430.068
nucleoside metabolic processGO:00091161270.067
sister chromatid segregationGO:0000819920.067
negative regulation of organelle organizationGO:0010639560.067
regulation of neuron differentiationGO:00456641030.065
oocyte differentiationGO:00099941450.061
regulation of organelle organizationGO:00330431960.061
purine nucleotide catabolic processGO:00061951090.060
centrosome cycleGO:00070981370.060
regulation of organ growthGO:0046620420.060
nucleoside triphosphate metabolic processGO:00091411200.059
meiotic cell cycle processGO:19030461320.059
Worm
positive regulation of cellular biosynthetic processGO:00313283160.059
glycosyl compound catabolic processGO:19016581120.059
cell divisionGO:00513012480.058
Mouse
negative regulation of phosphate metabolic processGO:0045936450.057
negative regulation of molecular functionGO:0044092510.056
regulation of intracellular signal transductionGO:19025312360.056
embryonic organ developmentGO:0048568500.055
nitrogen compound transportGO:0071705850.055
nuclear transportGO:0051169720.054
embryonic development via the syncytial blastodermGO:00017001480.054
female germ line cyst formationGO:0048135420.053
tissue deathGO:00162711020.052
negative regulation of mitotic cell cycle phase transitionGO:19019911030.052
regulation of multicellular organism growthGO:0040014400.052
oocyte localization involved in germarium derived egg chamber formationGO:0030720120.052
response to nutrient levelsGO:00316671140.052
purine nucleoside catabolic processGO:00061521120.051
positive regulation of cell developmentGO:0010720610.051
chromosome segregationGO:00070591570.051
small molecule metabolic processGO:00442813050.050
imaginal disc derived wing morphogenesisGO:00074763370.050
germarium derived female germ line cyst formationGO:0030727420.050
regulation of chromatin organizationGO:1902275320.050
negative regulation of sequence specific dna binding transcription factor activityGO:004343340.050
positive regulation of nucleic acid templated transcriptionGO:19035082660.049
positive regulation of intracellular signal transductionGO:19025331160.048
membrane organizationGO:00610241120.048
positive regulation of mitotic sister chromatid separationGO:1901970100.048
positive regulation of proteasomal protein catabolic processGO:1901800200.048
regulation of translationGO:0006417560.047
positive regulation of nucleobase containing compound metabolic processGO:00459353320.046
respiratory system developmentGO:00605412130.046
oocyte axis specificationGO:00073091080.046
regulation of cellular localizationGO:00603411360.045
developmental maturationGO:00217001720.045
regulation of transportGO:00510491810.045
establishment or maintenance of microtubule cytoskeleton polarityGO:0030951410.044
regulation of cell divisionGO:0051302720.044
positive regulation of signalingGO:00230562430.043
protein catabolic processGO:00301631010.043
post embryonic appendage morphogenesisGO:00351203850.042
negative regulation of growthGO:0045926840.042
response to organic substanceGO:00100332840.042
organophosphate catabolic processGO:00464341120.042
purine containing compound catabolic processGO:00725231120.041
positive regulation of molecular functionGO:00440931360.041
regulation of jnk cascadeGO:0046328400.041
response to hypoxiaGO:0001666530.041
instar larval developmentGO:0002168550.040
intracellular signal transductionGO:00355563000.040
salivary gland cell autophagic cell deathGO:0035071830.040
oocyte microtubule cytoskeleton polarizationGO:0008103220.040
regulation of intracellular transportGO:0032386640.040
negative regulation of cell cycleGO:00457861160.040
single organism membrane organizationGO:0044802930.040
cell growthGO:00160491080.040
positive regulation of nervous system developmentGO:0051962690.040
developmental cell growthGO:0048588520.039
protein maturationGO:0051604710.039
germline stem cell asymmetric divisionGO:0098728150.038
connective tissue developmentGO:006144830.038
embryo development ending in birth or egg hatchingGO:00097921520.038
Worm
phagocytosisGO:00069092150.038
positive regulation of cell communicationGO:00106472500.038
stem cell proliferationGO:0072089880.038
imaginal disc derived appendage developmentGO:00487373990.037
epithelial cell developmentGO:00020642740.037
cellular response to abiotic stimulusGO:0071214580.037
oocyte dorsal ventral axis specificationGO:0007310340.037
purine ribonucleoside triphosphate metabolic processGO:00092051190.036
stem cell divisionGO:0017145690.036
positive regulation of hydrolase activityGO:0051345780.036
eye developmentGO:00016543230.036
negative regulation of biosynthetic processGO:00098902770.036
male gamete generationGO:00482322010.035
regulation of purine nucleotide metabolic processGO:1900542620.035
regulation of cellular ketone metabolic processGO:001056530.035
purine containing compound metabolic processGO:00725211550.035
regulation of protein transportGO:0051223570.034
negative regulation of cell deathGO:0060548810.034
organonitrogen compound catabolic processGO:19015651280.034
positive regulation of nitrogen compound metabolic processGO:00511733540.034
larval developmentGO:00021641040.034
negative regulation of response to stimulusGO:00485852580.034
germarium derived female germ line cyst encapsulationGO:003070880.034
protein complex assemblyGO:00064612000.033
mapk cascadeGO:00001651070.033
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.033
purine ribonucleotide metabolic processGO:00091501450.033
dna endoreduplicationGO:0042023220.032
muscle cell differentiationGO:00426921030.032
methylationGO:0032259470.032
germarium derived oocyte differentiationGO:0030706290.032
ribonucleoprotein complex biogenesisGO:0022613310.032
response to uvGO:0009411240.032
regulation of chromosome segregationGO:0051983320.032
positive regulation of multicellular organism growthGO:0040018210.032
carbohydrate derivative metabolic processGO:19011352170.032
nuclear exportGO:0051168240.031
ion transportGO:00068111450.031
oocyte anterior posterior axis specificationGO:0007314720.031
nucleus organizationGO:0006997450.031
regulation of nucleocytoplasmic transportGO:0046822350.031
oocyte developmentGO:00485991240.030
reproductive system developmentGO:0061458740.030
Worm
purine ribonucleoside triphosphate catabolic processGO:00092071080.030
salivary gland morphogenesisGO:00074351450.030
cellular protein localizationGO:00346131600.030
negative regulation of catabolic processGO:0009895360.030
ovarian follicle cell stalk formationGO:0030713170.030
autophagic cell deathGO:0048102830.030
maintenance of locationGO:0051235730.030
stress activated mapk cascadeGO:0051403520.029
regulation of proteolysisGO:0030162870.029
small gtpase mediated signal transductionGO:0007264880.029
production of small rna involved in gene silencing by rnaGO:0070918150.029
lipid storageGO:0019915380.029
muscle structure developmentGO:00610612240.029
response to woundingGO:0009611940.028
histolysisGO:00075591020.028
maternal determination of anterior posterior axis embryoGO:0008358740.028
nucleoside catabolic processGO:00091641120.028
gene silencingGO:00164581380.028
regulation of establishment of protein localizationGO:0070201610.028
positive regulation of cell cycle processGO:0090068280.027
negative regulation of stress activated mapk cascadeGO:0032873190.027
spermatid developmentGO:0007286980.026
nucleoside triphosphate catabolic processGO:00091431080.026
nucleoside phosphate catabolic processGO:19012921100.026
striated muscle cell differentiationGO:0051146900.026
imaginal disc derived appendage morphogenesisGO:00351143950.025
regulation of protein localizationGO:0032880760.025
positive regulation of cell differentiationGO:0045597640.025
transcription from rna polymerase ii promoterGO:00063663680.025
cell motilityGO:00488702510.025
eye morphogenesisGO:00485922600.025
single organism catabolic processGO:00447122280.025
actin filament organizationGO:00070151260.025
regulation of nucleotide metabolic processGO:0006140620.025
nucleotide catabolic processGO:00091661090.024
development of primary sexual characteristicsGO:0045137500.024
Worm
skin developmentGO:0043588650.024
response to ketoneGO:1901654340.024
ribonucleoside catabolic processGO:00424541120.024
regulation of cell deathGO:00109411730.024
maintenance of protein locationGO:0045185280.024
rna interferenceGO:0016246270.024
posttranscriptional regulation of gene expressionGO:00106081450.024
cellular protein complex disassemblyGO:0043624350.024
negative regulation of gene expression epigeneticGO:0045814770.024
response to light stimulusGO:00094161240.024
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052240.023
cuticle developmentGO:0042335860.023
salivary gland histolysisGO:0035070880.023
regulation of exit from mitosisGO:000709670.023
regulation of notch signaling pathwayGO:00085931000.023
negative regulation of signalingGO:00230572190.023
protein localizationGO:00081042840.023
gland developmentGO:00487321910.023
anterior posterior axis specificationGO:00099481090.023
positive regulation of developmental growthGO:0048639620.023
locomotory behaviorGO:00076261760.023
innate immune responseGO:00450871440.022
gtp metabolic processGO:0046039720.022
purine ribonucleotide catabolic processGO:00091541090.022
digestive system developmentGO:00551231490.021
microtubule based movementGO:0007018510.021
cellular response to sterol depletionGO:007150130.021
eggshell chorion assemblyGO:0007306660.021
organic acid metabolic processGO:00060821030.021
pole plasm assemblyGO:0007315610.021
response to ecdysoneGO:0035075340.021
endomembrane system organizationGO:00102561190.021
head developmentGO:00603221350.021
positive regulation of phosphate metabolic processGO:00459371390.021
tube morphogenesisGO:00352391910.021
open tracheal system developmentGO:00074242040.021
genitalia developmentGO:0048806260.021
regionalizationGO:00030024160.021
regulation of organ morphogenesisGO:2000027780.020
protein complex biogenesisGO:00702712010.020
negative regulation of nervous system developmentGO:0051961920.020
establishment of protein localizationGO:00451841630.020
compound eye photoreceptor cell differentiationGO:00017511400.020
heterochromatin organization involved in chromatin silencingGO:007086890.020
purine nucleotide metabolic processGO:00061631460.020
response to decreased oxygen levelsGO:0036293580.020
macromolecular complex disassemblyGO:0032984370.020
forebrain developmentGO:003090020.020
positive regulation of cellular protein catabolic processGO:1903364240.020
gene silencing by rnaGO:0031047570.020
eggshell formationGO:00307031050.020
negative regulation of cell cycle processGO:00109481090.020
regulation of protein import into nucleusGO:0042306280.020
regulation of protein modification by small protein conjugation or removalGO:1903320250.019
negative regulation of phosphorylationGO:0042326350.019
segmentationGO:00352822070.019
atp metabolic processGO:0046034490.019
fusome organizationGO:0045478130.019
regulation of dna metabolic processGO:0051052340.019
regulation of epithelial cell differentiationGO:003085640.019
regulation of catalytic activityGO:00507901850.019
maintenance of protein location in cellGO:0032507260.019
regulation of mitotic spindle organizationGO:006023690.019
protein localization to nucleusGO:0034504550.018
posttranscriptional gene silencingGO:0016441460.018
positive regulation of proteolysisGO:0045862520.018
regulation of chromatin bindingGO:003556130.018
golgi vesicle transportGO:0048193270.018
positive regulation of metaphase anaphase transition of cell cycleGO:1902101100.018
nucleoside monophosphate catabolic processGO:0009125390.018
negative regulation of cellular catabolic processGO:0031330340.018
regulation of chromatin modificationGO:1903308280.017
regulation of anatomical structure sizeGO:00900661630.017
localization of cellGO:00516742570.017
regulation of cell cycle g1 s phase transitionGO:1902806230.017
ribonucleotide catabolic processGO:00092611090.017
cell cycle arrestGO:000705040.017
mitochondrion localizationGO:0051646170.017
establishment of planar polarityGO:0001736870.017
fertilizationGO:0009566260.017
negative regulation of intracellular signal transductionGO:1902532570.017
mitotic g2 m transition checkpointGO:0044818700.017
neuroblast proliferationGO:0007405740.017
ribonucleoside metabolic processGO:00091191270.017
dna conformation changeGO:00711031050.017
mitotic sister chromatid segregationGO:0000070870.017
negative regulation of protein processingGO:0010955310.016
golgi organizationGO:0007030660.016
protein processingGO:0016485680.016
regulation of mapk cascadeGO:0043408920.016
cellular amino acid metabolic processGO:0006520610.016
negative regulation of rna biosynthetic processGO:19026792400.016
regulation of cellular response to stressGO:0080135890.016
positive regulation of neuron differentiationGO:0045666260.016
positive regulation of catalytic activityGO:00430851180.016
mitotic dna damage checkpointGO:0044773740.015
regulation of programmed cell deathGO:00430671520.015
positive regulation of transcription dna templatedGO:00458932660.015
positive regulation of neurogenesisGO:0050769410.015
oocyte nucleus localization involved in oocyte dorsal ventral axis specificationGO:0051663120.015
cellular protein complex assemblyGO:0043623710.015
regulation of immune effector processGO:0002697520.015
positive regulation of cellular component organizationGO:00511301560.015
rna localizationGO:00064031150.015
cellular amine metabolic processGO:0044106120.015
regulation of stress activated protein kinase signaling cascadeGO:0070302420.015
mrna metabolic processGO:00160711240.015
regulation of cytoplasmic transportGO:1903649470.015
regulation of cellular amine metabolic processGO:003323830.014
regulation of mitotic sister chromatid segregationGO:0033047280.014
negative regulation of translationGO:0017148280.014
establishment or maintenance of cell polarityGO:00071631670.014
protein k48 linked ubiquitinationGO:007093630.014
phenol containing compound metabolic processGO:0018958570.014
stress activated protein kinase signaling cascadeGO:0031098550.014
long term memoryGO:0007616620.014
larval lymph gland hemopoiesisGO:0035167170.014
microtubule organizing center organizationGO:00310231680.014
positive regulation of phosphorus metabolic processGO:00105621390.014
establishment of meiotic spindle orientationGO:005129620.014
chromatin assembly or disassemblyGO:0006333520.014
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.014
response to biotic stimulusGO:00096072940.014
oxoacid metabolic processGO:00434361030.014
heart field specificationGO:000312800.014
anterior posterior pattern specificationGO:00099521360.014
imaginal disc growthGO:0007446370.014
negative regulation of cellular component organizationGO:00511291080.013
purine ribonucleoside metabolic processGO:00461281270.013
spindle stabilizationGO:0043146140.013
taxisGO:00423303040.013
protein polyubiquitinationGO:0000209110.013
regulation of cell developmentGO:00602842150.013
regulation of lipid metabolic processGO:0019216150.013
germ line cyst formationGO:0048134440.013
negative regulation of stress activated protein kinase signaling cascadeGO:0070303200.013
cell fate specificationGO:0001708710.013
nuclear envelope organizationGO:000699870.013
ras protein signal transductionGO:0007265880.013
protein importGO:0017038550.013
regulation of nervous system developmentGO:00519602480.013
regulation of neuron projection developmentGO:0010975690.013
purine ribonucleoside monophosphate metabolic processGO:0009167500.013
regulation of cytoskeleton organizationGO:0051493890.012
sensory organ morphogenesisGO:00905962600.012
negative regulation of phosphorus metabolic processGO:0010563450.012
hindgut developmentGO:0061525580.012

Top1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.115
disease of cellular proliferationDOID:1456600.024
cancerDOID:16200.024
nervous system diseaseDOID:86300.013
neurodegenerative diseaseDOID:128900.013
central nervous system diseaseDOID:33100.013