Drosophila melanogaster

111 known processes

Timp (Dmel_CG6281)

Tissue inhibitor of metalloproteases

(Aliases: DTIMP,TIMP,CG6281,timp,Dmel\CG6281,Dtimp,dTIMP)

Timp biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of tube length open tracheal systemGO:0035159240.884
regulation of tube architecture open tracheal systemGO:0035152680.778
regulation of defense responseGO:00313471020.643
dorsal trunk growth open tracheal systemGO:003500170.625
cellular response to light stimulusGO:0071482370.581
regulation of immune system processGO:00026821760.504
regulation of tube size open tracheal systemGO:0035151430.484
cellular response to abiotic stimulusGO:0071214580.453
open tracheal system developmentGO:00074242040.391
regulation of immune responseGO:00507761180.282
cellular response to radiationGO:0071478520.280
immune effector processGO:0002252980.273
cell adhesionGO:00071551360.271
molting cycle chitin based cuticleGO:0007591560.268
extracellular matrix disassemblyGO:002261740.261
anatomical structure homeostasisGO:0060249970.251
response to fibroblast growth factorGO:0071774100.240
regulation of tube sizeGO:0035150460.240
extracellular structure organizationGO:0043062460.227
tracheal outgrowth open tracheal systemGO:0007426180.219
regulation of response to stressGO:00801342000.198
immune system processGO:00023763470.192
negative regulation of cell communicationGO:00106482230.175
positive regulation of defense responseGO:0031349590.171
cellular component disassemblyGO:0022411460.165
catabolic processGO:00090564090.163
Human
positive regulation of response to stimulusGO:00485843230.162
activation of innate immune responseGO:000221840.158
negative regulation of signalingGO:00230572190.154
gland morphogenesisGO:00226121450.152
regenerationGO:0031099160.150
biological adhesionGO:00226101380.150
positive regulation of cellular biosynthetic processGO:00313283160.133
regulation of innate immune responseGO:0045088710.132
positive regulation of immune responseGO:0050778630.127
imaginal disc derived appendage morphogenesisGO:00351143950.125
negative regulation of multicellular organismal processGO:00512411420.125
Human
response to light stimulusGO:00094161240.122
response to woundingGO:0009611940.108
respiratory system developmentGO:00605412130.107
growthGO:00400073590.104
molting cycleGO:0042303560.101
developmental growthGO:00485892800.096
positive regulation of immune system processGO:0002684680.086
defense responseGO:00069523000.086
negative regulation of fibroblast growth factor receptor signaling pathwayGO:004003720.084
cellular metal ion homeostasisGO:0006875310.068
regulation of anatomical structure sizeGO:00900661630.067
cell recognitionGO:00080371020.066
lateral inhibitionGO:00463312060.066
negative regulation of signal transductionGO:00099682060.059
positive regulation of biosynthetic processGO:00098913160.059
homeostatic processGO:00425921990.056
regulation of cell differentiationGO:00455953020.054
Mouse
negative regulation of response to stimulusGO:00485852580.053
post embryonic appendage morphogenesisGO:00351203850.053
salivary gland developmentGO:00074311620.053
mapk cascadeGO:00001651070.052
Mouse
positive regulation of developmental processGO:00510941430.052
melanin metabolic processGO:0006582470.050
cellular response to fibroblast growth factor stimulusGO:0044344100.049
substrate adhesion dependent cell spreadingGO:003444620.049
muscle cell developmentGO:0055001500.049
small molecule metabolic processGO:00442813050.049
Mouse
developmental growth involved in morphogenesisGO:0060560650.049
response to organic cyclic compoundGO:0014070890.049
innate immune responseGO:00450871440.048
salivary gland morphogenesisGO:00074351450.048
regulation of phosphorus metabolic processGO:00511742100.048
Mouse
sterol homeostasisGO:005509240.048
immune responseGO:00069552460.046
extracellular matrix organizationGO:0030198320.045
positive regulation of immune effector processGO:0002699280.043
circadian sleep wake cycle processGO:0022410240.043
response to lipopolysaccharideGO:003249640.043
regulation of epithelial cell migration open tracheal systemGO:2000274110.042
histolysisGO:00075591020.042
response to high light intensityGO:000964410.042
heart processGO:0003015370.041
proteolysisGO:00065081920.041
regulation of cell proliferationGO:00421271630.041
Human Mouse
positive regulation of phosphate metabolic processGO:00459371390.040
regulation of response to woundingGO:1903034190.040
organic cyclic compound catabolic processGO:19013611680.040
response to radiationGO:00093141550.039
cellular response to endogenous stimulusGO:0071495800.039
regulation of circadian rhythmGO:0042752490.039
regulation of proteolysisGO:0030162870.039
positive regulation of nitrogen compound metabolic processGO:00511733540.039
cellular response to light intensityGO:007148410.039
regulation of phosphorylationGO:00423251470.038
Mouse
response to organic substanceGO:00100332840.037
Mouse
instar larval developmentGO:0002168550.037
positive regulation of cell migrationGO:003033520.037
microtubule organizing center organizationGO:00310231680.037
gland developmentGO:00487321910.036
exocrine system developmentGO:00352721620.036
carboxylic acid metabolic processGO:0019752920.035
deathGO:00162652840.035
protein modification processGO:00362114380.035
cellular catabolic processGO:00442483720.035
Human
positive regulation of signalingGO:00230562430.035
regulation of mapk cascadeGO:0043408920.034
Mouse
wing disc morphogenesisGO:00074723440.034
positive regulation of phosphorus metabolic processGO:00105621390.033
organelle assemblyGO:00709251980.032
organic substance catabolic processGO:19015753080.032
Human
learning or memoryGO:00076111410.032
catecholamine biosynthetic processGO:004242330.032
cellular homeostasisGO:0019725800.031
imaginal disc derived appendage developmentGO:00487373990.031
centrosome organizationGO:00512971630.030
dopamine biosynthetic processGO:004241630.030
regulation of multicellular organismal developmentGO:20000264140.030
Human Mouse
kidney developmentGO:000182230.030
regulation of response to external stimulusGO:00321011150.029
negative regulation of rna metabolic processGO:00512532510.029
endocytosisGO:00068973100.029
regulation of cellular protein metabolic processGO:00322682430.029
indole containing compound biosynthetic processGO:004243540.028
cell cell signaling involved in cell fate commitmentGO:00451682100.028
tissue deathGO:00162711020.028
connective tissue developmentGO:006144830.027
single organism catabolic processGO:00447122280.026
centrosome duplicationGO:00512981210.026
negative regulation of cellular metabolic processGO:00313243820.026
myotube cell developmentGO:001490430.026
programmed cell deathGO:00125012570.026
regulation of immune effector processGO:0002697520.025
establishment or maintenance of cell polarityGO:00071631670.025
cuticle pigmentationGO:0048067220.025
cellular response to high light intensityGO:007148610.025
establishment of localization in cellGO:00516494020.025
cellular chemical homeostasisGO:0055082400.024
salivary gland cell autophagic cell deathGO:0035071830.024
cellular response to growth factor stimulusGO:0071363300.024
positive regulation of innate immune responseGO:0045089380.024
cellular response to organic substanceGO:00713101320.024
Mouse
fluid transportGO:0042044190.023
rhythmic processGO:00485111060.023
aromatic compound catabolic processGO:00194391660.023
extrinsic apoptotic signaling pathwayGO:009719110.023
negative regulation of cell differentiationGO:00455961430.023
carbohydrate derivative biosynthetic processGO:1901137850.022
response to endogenous stimulusGO:00097191190.022
phosphorylationGO:00163102940.022
Mouse
cellular component assembly involved in morphogenesisGO:00109271510.022
pigment metabolic processGO:0042440840.022
positive regulation of protein metabolic processGO:00512471280.022
regulation of tube diameter open tracheal systemGO:0035158110.022
regionalizationGO:00030024160.022
cellular protein modification processGO:00064644380.022
muscle attachmentGO:0016203360.022
cellular ion homeostasisGO:0006873390.021
protein phosphorylationGO:00064681690.021
positive regulation of cell communicationGO:00106472500.021
production of molecular mediator of immune responseGO:0002440460.021
purine nucleoside catabolic processGO:00061521120.021
negative regulation of cellular response to growth factor stimulusGO:009028860.020
purine ribonucleotide metabolic processGO:00091501450.020
Mouse
imaginal disc growthGO:0007446370.020
protein transportGO:00150311550.020
vesicle mediated transportGO:00161923810.020
organic substance transportGO:00717022570.020
epibolyGO:009050420.019
cation homeostasisGO:0055080510.019
regulation of cell morphogenesis involved in differentiationGO:0010769610.019
single organism behaviorGO:00447083910.019
body morphogenesisGO:001017120.019
cell deathGO:00082192790.019
cellular macromolecule catabolic processGO:00442651360.019
establishment of protein localizationGO:00451841630.018
memoryGO:0007613940.018
appendage morphogenesisGO:00351073970.018
phagocytosisGO:00069092150.018
regulation of multi organism processGO:00439001310.018
Human
agingGO:00075681430.018
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.018
gene silencingGO:00164581380.018
melanization defense responseGO:0035006450.017
epithelial structure maintenanceGO:0010669170.017
macromolecule catabolic processGO:00090571610.017
Human
regulation of wnt signaling pathwayGO:0030111680.017
regulation of anatomical structure morphogenesisGO:00226032420.017
localization of cellGO:00516742570.017
Human
response to ecdysoneGO:0035075340.017
nucleotide metabolic processGO:00091171610.017
Mouse
regulation of cell substrate adhesionGO:001081020.017
oxoacid metabolic processGO:00434361030.017
imaginal disc eversionGO:000756140.017
developmental programmed cell deathGO:00106231380.017
cardiovascular system developmentGO:0072358820.017
steroid catabolic processGO:000670610.017
positive regulation of signal transductionGO:00099672230.017
imaginal disc derived wing morphogenesisGO:00074763370.017
skeletal muscle organ developmentGO:0060538480.016
positive regulation of protein kinase activityGO:0045860250.016
organonitrogen compound metabolic processGO:19015643180.016
Mouse
response to abiotic stimulusGO:00096283410.016
terminal branching open tracheal systemGO:0007430170.015
protein localizationGO:00081042840.015
imaginal disc fusionGO:0046528190.015
regulation of protein modification processGO:00313991120.015
positive regulation of macromolecule biosynthetic processGO:00105572830.015
regulation of establishment of protein localizationGO:0070201610.015
dephosphorylationGO:0016311510.015
cell agingGO:000756920.015
organonitrogen compound biosynthetic processGO:19015661170.015
positive regulation of response to biotic stimulusGO:0002833310.014
response to bacteriumGO:00096171980.014
positive regulation of antimicrobial peptide biosynthetic processGO:0002807260.014
cell proliferationGO:00082832990.014
Human Mouse
heterocycle catabolic processGO:00467001660.014
sensory perceptionGO:00076001960.014
sensory organ morphogenesisGO:00905962600.014
positive regulation of cell motilityGO:200014730.014
axis specificationGO:00097981670.014
response to growth factorGO:0070848310.014
organic hydroxy compound metabolic processGO:1901615830.014
cellular amide metabolic processGO:0043603800.014
myofibril assemblyGO:0030239360.014
positive regulation of growthGO:0045927750.014
mitochondrion organizationGO:0007005650.014
rhythmic behaviorGO:0007622760.014
cellular macromolecular complex assemblyGO:00346221530.014
cellular response to organic cyclic compoundGO:0071407320.013
wound healingGO:0042060750.013
establishment or maintenance of bipolar cell polarityGO:0061245340.013
ribose phosphate metabolic processGO:00196931450.013
Mouse
autophagic cell deathGO:0048102830.013
camera type eye morphogenesisGO:004859320.013
cellular ketone metabolic processGO:0042180240.013
cellular response to molecule of bacterial originGO:007121930.013
encapsulation of foreign targetGO:0035010380.013
muscle tissue morphogenesisGO:006041520.013
long term memoryGO:0007616620.013
aromatic amino acid family metabolic processGO:000907230.013
cellular response to dna damage stimulusGO:00069742230.013
embryonic development via the syncytial blastodermGO:00017001480.013
regulation of synaptic transmissionGO:0050804690.013
basement membrane organizationGO:0071711100.013
organic acid metabolic processGO:00060821030.013
intracellular signal transductionGO:00355563000.013
Mouse
regulation of neural precursor cell proliferationGO:2000177350.013
ribonucleotide catabolic processGO:00092611090.013
regulation of localizationGO:00328792750.012
Human
epithelial cell migration open tracheal systemGO:0007427320.012
positive regulation of nucleobase containing compound metabolic processGO:00459353320.012
phenol containing compound metabolic processGO:0018958570.012
leg disc morphogenesisGO:0007478800.012
regulation of cell divisionGO:0051302720.012
mitotic cytokinesisGO:0000281500.012
immune response activating signal transductionGO:000275720.012
regulation of hydrolase activityGO:0051336970.012
positive regulation of response to external stimulusGO:0032103440.012
tissue homeostasisGO:0001894360.012
epiboly involved in wound healingGO:009050520.012
establishment or maintenance of cytoskeleton polarityGO:0030952440.012
negative regulation of cellular component organizationGO:00511291080.012
hindbrain developmentGO:003090220.012
proteolysis involved in cellular protein catabolic processGO:0051603830.012
negative regulation of macromolecule biosynthetic processGO:00105582700.012
positive regulation of rna biosynthetic processGO:19026802660.012
negative regulation of stem cell proliferationGO:2000647300.012
antifungal humoral responseGO:0019732120.012
enzyme linked receptor protein signaling pathwayGO:00071671790.012
primary amino compound biosynthetic processGO:190116220.011
neuron recognitionGO:00080381010.011
regulation of cell deathGO:00109411730.011
imaginal disc fusion thorax closureGO:0046529190.011
jnk cascadeGO:0007254500.011
salivary gland histolysisGO:0035070880.011
positive regulation of phosphorylationGO:0042327870.011
peptide metabolic processGO:0006518800.011
regulation of response to biotic stimulusGO:0002831630.011
negative regulation of gene expression epigeneticGO:0045814770.011
muscle organ developmentGO:00075171270.011
fibroblast growth factor receptor signaling pathwayGO:0008543100.011
larval developmentGO:00021641040.011
signal transduction by phosphorylationGO:00230141070.011
Mouse
serotonin metabolic processGO:004242820.011
protein catabolic processGO:00301631010.011
Human
dorsal ventral pattern formationGO:00099531330.011
negative regulation of developmental processGO:00510932010.011
Human
positive regulation of cellular amine metabolic processGO:003324000.011
skeletal muscle fiber developmentGO:004874130.011
nucleoside phosphate metabolic processGO:00067531620.010
Mouse
regulation of nervous system developmentGO:00519602480.010
Mouse
cellular response to biotic stimulusGO:007121640.010
positive regulation of protein serine threonine kinase activityGO:0071902150.010
neural precursor cell proliferationGO:0061351750.010
protein secretionGO:0009306450.010
segmentationGO:00352822070.010
cytoskeleton dependent cytokinesisGO:0061640810.010
striated muscle myosin thick filament assemblyGO:007168830.010
regulation of kinase activityGO:0043549530.010
regulation of protein metabolic processGO:00512462560.010
regulation of cell adhesionGO:0030155270.010

Timp disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.021
nervous system diseaseDOID:86300.017
bone diseaseDOID:008000100.016
connective tissue diseaseDOID:6500.016
musculoskeletal system diseaseDOID:1700.016
vascular diseaseDOID:17800.011
artery diseaseDOID:005082800.011
cardiovascular system diseaseDOID:128700.011