| regulation of gene expression epigenetic | GO:0040029 | 128 | 0.921 | |
| negative regulation of gene expression | GO:0010629 | 387 | 0.788 | |
| negative regulation of cellular macromolecule biosynthetic process | GO:2000113 | 267 | 0.712 | |
| negative regulation of cellular biosynthetic process | GO:0031327 | 277 | 0.648 | |
| internal protein amino acid acetylation | GO:0006475 | 38 | 0.640 | |
| macromolecular complex assembly | GO:0065003 | 256 | 0.639 | |
| chromatin organization | GO:0006325 | 207 | 0.630 | |
| peptidyl lysine modification | GO:0018205 | 57 | 0.606 | |
| negative regulation of biosynthetic process | GO:0009890 | 277 | 0.603 | |
| negative regulation of rna metabolic process | GO:0051253 | 251 | 0.600 | |
| negative regulation of cellular metabolic process | GO:0031324 | 382 | 0.596 | |
| negative regulation of gene expression epigenetic | GO:0045814 | 77 | 0.554 | |
| chromatin silencing | GO:0006342 | 76 | 0.471 | |
| dna conformation change | GO:0071103 | 105 | 0.466 | |
| negative regulation of nitrogen compound metabolic process | GO:0051172 | 265 | 0.460 | |
| negative regulation of transcription dna templated | GO:0045892 | 237 | 0.456 | |
| internal peptidyl lysine acetylation | GO:0018393 | 38 | 0.421 | |
| negative regulation of nucleic acid templated transcription | GO:1903507 | 240 | 0.416 | |
| peptidyl lysine acetylation | GO:0018394 | 39 | 0.412 | |
| protein dna complex subunit organization | GO:0071824 | 86 | 0.410 | |
| negative regulation of nucleobase containing compound metabolic process | GO:0045934 | 261 | 0.401 | |
| histone acetylation | GO:0016573 | 38 | 0.396 | |
| nucleosome organization | GO:0034728 | 59 | 0.389 | |
| chromatin modification | GO:0016568 | 147 | 0.367 | |
| chromosome organization | GO:0051276 | 360 | 0.352 | |
| cellular macromolecular complex assembly | GO:0034622 | 153 | 0.334 | |
| dna metabolic process | GO:0006259 | 227 | 0.325 | Human Yeast |
| protein dna complex assembly | GO:0065004 | 63 | 0.323 | |
| transcription from rna polymerase ii promoter | GO:0006366 | 368 | 0.301 | Yeast |
| positive regulation of macromolecule metabolic process | GO:0010604 | 405 | 0.292 | |
| negative regulation of rna biosynthetic process | GO:1902679 | 240 | 0.279 | |
| striated muscle cell differentiation | GO:0051146 | 90 | 0.257 | |
| chromatin assembly or disassembly | GO:0006333 | 52 | 0.257 | |
| g2 dna damage checkpoint | GO:0031572 | 69 | 0.248 | |
| chromatin assembly | GO:0031497 | 48 | 0.248 | |
| organelle assembly | GO:0070925 | 198 | 0.216 | |
| gene silencing | GO:0016458 | 138 | 0.212 | |
| negative regulation of macromolecule biosynthetic process | GO:0010558 | 270 | 0.209 | |
| protein modification process | GO:0036211 | 438 | 0.195 | |
| cellular protein modification process | GO:0006464 | 438 | 0.192 | |
| protein complex assembly | GO:0006461 | 200 | 0.189 | |
| dna damage checkpoint | GO:0000077 | 78 | 0.185 | |
| histone modification | GO:0016570 | 106 | 0.183 | |
| positive regulation of nucleic acid templated transcription | GO:1903508 | 266 | 0.172 | |
| regulation of cellular amine metabolic process | GO:0033238 | 3 | 0.154 | |
| chromatin remodeling | GO:0006338 | 72 | 0.147 | |
| positive regulation of macromolecule biosynthetic process | GO:0010557 | 283 | 0.141 | |
| positive regulation of transcription dna templated | GO:0045893 | 266 | 0.139 | |
| cell cycle checkpoint | GO:0000075 | 95 | 0.137 | |
| protein complex biogenesis | GO:0070271 | 201 | 0.137 | |
| peptidyl amino acid modification | GO:0018193 | 105 | 0.132 | |
| positive regulation of rna biosynthetic process | GO:1902680 | 266 | 0.131 | |
| cellular response to dna damage stimulus | GO:0006974 | 223 | 0.128 | Human Yeast |
| dna integrity checkpoint | GO:0031570 | 81 | 0.110 | |
| body morphogenesis | GO:0010171 | 2 | 0.110 | |
| cellular macromolecule localization | GO:0070727 | 220 | 0.110 | |
| cell cycle phase transition | GO:0044770 | 140 | 0.108 | |
| dendrite development | GO:0016358 | 204 | 0.108 | |
| tissue migration | GO:0090130 | 155 | 0.105 | |
| covalent chromatin modification | GO:0016569 | 106 | 0.098 | |
| positive regulation of cellular biosynthetic process | GO:0031328 | 316 | 0.095 | |
| positive regulation of gene expression | GO:0010628 | 290 | 0.094 | |
| protein localization | GO:0008104 | 284 | 0.091 | |
| positive regulation of biosynthetic process | GO:0009891 | 316 | 0.089 | |
| positive regulation of rna metabolic process | GO:0051254 | 271 | 0.087 | |
| embryo development ending in birth or egg hatching | GO:0009792 | 152 | 0.086 | |
| muscle structure development | GO:0061061 | 224 | 0.080 | |
| protein acylation | GO:0043543 | 42 | 0.080 | |
| gonad development | GO:0008406 | 50 | 0.075 | |
| mitotic g2 m transition checkpoint | GO:0044818 | 70 | 0.073 | |
| mitotic dna damage checkpoint | GO:0044773 | 74 | 0.072 | |
| regulation of transcription from rna polymerase ii promoter | GO:0006357 | 378 | 0.072 | Yeast |
| protein acetylation | GO:0006473 | 39 | 0.064 | |
| negative regulation of meiotic cell cycle | GO:0051447 | 2 | 0.063 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 0 | 0.063 | |
| dendrite morphogenesis | GO:0048813 | 199 | 0.063 | |
| regulation of protein transport | GO:0051223 | 57 | 0.062 | |
| establishment of protein localization | GO:0045184 | 163 | 0.060 | |
| histone exchange | GO:0043486 | 21 | 0.057 | |
| regulation of cell morphogenesis | GO:0022604 | 163 | 0.057 | |
| muscle cell differentiation | GO:0042692 | 103 | 0.054 | |
| histone h4 acetylation | GO:0043967 | 13 | 0.054 | Human |
| response to organic substance | GO:0010033 | 284 | 0.052 | |
| dorsal ventral pattern formation | GO:0009953 | 133 | 0.051 | |
| nucleosome assembly | GO:0006334 | 35 | 0.051 | |
| organelle fission | GO:0048285 | 340 | 0.050 | |
| histone h4 k20 methylation | GO:0034770 | 4 | 0.050 | |
| regionalization | GO:0003002 | 416 | 0.050 | |
| protein localization to organelle | GO:0033365 | 82 | 0.049 | |
| negative regulation of cell cycle process | GO:0010948 | 109 | 0.048 | |
| positive regulation of nitrogen compound metabolic process | GO:0051173 | 354 | 0.048 | |
| actin filament based process | GO:0030029 | 220 | 0.047 | |
| positive regulation of response to stimulus | GO:0048584 | 323 | 0.047 | |
| regulation of chromatin silencing | GO:0031935 | 36 | 0.047 | |
| amine metabolic process | GO:0009308 | 12 | 0.047 | |
| regulation of phosphate metabolic process | GO:0019220 | 210 | 0.046 | |
| muscle cell development | GO:0055001 | 50 | 0.046 | |
| nuclear division | GO:0000280 | 332 | 0.046 | |
| neurological system process | GO:0050877 | 358 | 0.046 | |
| anatomical structure homeostasis | GO:0060249 | 97 | 0.045 | |
| regulation of meiosis | GO:0040020 | 3 | 0.045 | |
| positive regulation of signal transduction | GO:0009967 | 223 | 0.045 | |
| defense response to bacterium | GO:0042742 | 178 | 0.044 | |
| regulation of cell cycle | GO:0051726 | 291 | 0.044 | |
| regulation of anatomical structure morphogenesis | GO:0022603 | 242 | 0.042 | |
| regulation of multi organism process | GO:0043900 | 131 | 0.041 | |
| rna catabolic process | GO:0006401 | 37 | 0.041 | |
| chromosome segregation | GO:0007059 | 157 | 0.040 | |
| peptidyl lysine trimethylation | GO:0018023 | 6 | 0.040 | |
| protein phosphorylation | GO:0006468 | 169 | 0.040 | |
| dna packaging | GO:0006323 | 91 | 0.039 | |
| negative regulation of cell cycle | GO:0045786 | 116 | 0.039 | |
| determination of dorsal ventral asymmetry | GO:0048262 | 3 | 0.038 | |
| embryonic morphogenesis | GO:0048598 | 206 | 0.038 | |
| meiotic cell cycle process | GO:1903046 | 132 | 0.038 | |
| regulation of heterochromatin assembly | GO:0031445 | 8 | 0.038 | |
| cellular component assembly involved in morphogenesis | GO:0010927 | 151 | 0.038 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 3 | 0.038 | |
| defense response to other organism | GO:0098542 | 225 | 0.037 | |
| reproductive behavior | GO:0019098 | 122 | 0.037 | |
| cytokinesis | GO:0000910 | 90 | 0.036 | |
| regulation of dna metabolic process | GO:0051052 | 34 | 0.035 | Yeast |
| establishment or maintenance of cell polarity | GO:0007163 | 167 | 0.035 | |
| negative regulation of transcription from rna polymerase ii promoter | GO:0000122 | 119 | 0.035 | |
| digestive tract morphogenesis | GO:0048546 | 127 | 0.034 | |
| carboxylic acid metabolic process | GO:0019752 | 92 | 0.033 | |
| mitotic cell cycle checkpoint | GO:0007093 | 88 | 0.033 | |
| cell fate specification | GO:0001708 | 71 | 0.033 | |
| multicellular organismal reproductive behavior | GO:0033057 | 110 | 0.033 | |
| regulation of phosphorus metabolic process | GO:0051174 | 210 | 0.033 | |
| regulation of organelle organization | GO:0033043 | 196 | 0.032 | |
| positive regulation of transcription from rna polymerase ii promoter | GO:0045944 | 204 | 0.032 | |
| positive regulation of cellular amine metabolic process | GO:0033240 | 0 | 0.032 | |
| positive regulation of nucleobase containing compound metabolic process | GO:0045935 | 332 | 0.032 | |
| regulation of dna templated transcription elongation | GO:0032784 | 17 | 0.032 | |
| macromolecule catabolic process | GO:0009057 | 161 | 0.031 | |
| rna processing | GO:0006396 | 147 | 0.031 | |
| multicellular organismal aging | GO:0010259 | 140 | 0.030 | |
| response to radiation | GO:0009314 | 155 | 0.030 | |
| signal transduction by phosphorylation | GO:0023014 | 107 | 0.029 | |
| intracellular transport | GO:0046907 | 228 | 0.029 | |
| cellular amino acid metabolic process | GO:0006520 | 61 | 0.029 | |
| epithelial cell development | GO:0002064 | 274 | 0.029 | |
| cellular ketone metabolic process | GO:0042180 | 24 | 0.029 | |
| meiotic nuclear division | GO:0007126 | 151 | 0.029 | |
| regulation of protein modification process | GO:0031399 | 112 | 0.028 | |
| mitotic cell cycle phase transition | GO:0044772 | 138 | 0.028 | |
| spindle assembly involved in mitosis | GO:0090307 | 50 | 0.028 | |
| positive regulation of cell communication | GO:0010647 | 250 | 0.027 | |
| epithelium migration | GO:0090132 | 148 | 0.027 | |
| negative regulation of protein metabolic process | GO:0051248 | 85 | 0.026 | |
| regulation of protein metabolic process | GO:0051246 | 256 | 0.026 | |
| chromatin silencing at centromere | GO:0030702 | 3 | 0.026 | |
| mitotic g2 dna damage checkpoint | GO:0007095 | 69 | 0.025 | |
| striated muscle cell development | GO:0055002 | 50 | 0.025 | |
| homeostatic process | GO:0042592 | 199 | 0.025 | |
| phosphorylation | GO:0016310 | 294 | 0.025 | |
| cellular protein complex assembly | GO:0043623 | 71 | 0.025 | |
| embryonic hindgut morphogenesis | GO:0048619 | 48 | 0.024 | |
| immune system process | GO:0002376 | 347 | 0.023 | |
| small molecule metabolic process | GO:0044281 | 305 | 0.023 | |
| phagocytosis | GO:0006909 | 215 | 0.023 | |
| single organism cellular localization | GO:1902580 | 180 | 0.023 | |
| dna dependent dna replication | GO:0006261 | 17 | 0.022 | Yeast |
| response to abiotic stimulus | GO:0009628 | 341 | 0.022 | |
| response to heat | GO:0009408 | 63 | 0.022 | |
| negative regulation of cell cycle phase transition | GO:1901988 | 103 | 0.021 | |
| tube morphogenesis | GO:0035239 | 191 | 0.021 | |
| stem cell division | GO:0017145 | 69 | 0.021 | |
| protein maturation | GO:0051604 | 71 | 0.021 | |
| mitotic dna integrity checkpoint | GO:0044774 | 75 | 0.021 | |
| morphogenesis of follicular epithelium | GO:0016333 | 36 | 0.021 | |
| response to external biotic stimulus | GO:0043207 | 293 | 0.021 | |
| positive regulation of cellular component biogenesis | GO:0044089 | 80 | 0.021 | |
| regulation of cell cycle process | GO:0010564 | 181 | 0.020 | |
| tissue morphogenesis | GO:0048729 | 297 | 0.020 | |
| positive regulation of intracellular transport | GO:0032388 | 42 | 0.020 | |
| growth | GO:0040007 | 359 | 0.020 | |
| negative regulation of cellular component organization | GO:0051129 | 108 | 0.020 | |
| response to biotic stimulus | GO:0009607 | 294 | 0.020 | |
| peptidyl lysine dimethylation | GO:0018027 | 3 | 0.020 | |
| male meiosis | GO:0007140 | 52 | 0.020 | |
| organic substance catabolic process | GO:1901575 | 308 | 0.019 | |
| negative regulation of molecular function | GO:0044092 | 51 | 0.019 | |
| positive regulation of gene expression epigenetic | GO:0045815 | 16 | 0.019 | |
| mrna catabolic process | GO:0006402 | 33 | 0.019 | |
| negative regulation of chromatin silencing | GO:0031936 | 9 | 0.019 | |
| endocytosis | GO:0006897 | 310 | 0.019 | |
| response to oxygen containing compound | GO:1901700 | 200 | 0.019 | |
| spindle assembly | GO:0051225 | 80 | 0.019 | |
| muscle organ development | GO:0007517 | 127 | 0.019 | |
| catabolic process | GO:0009056 | 409 | 0.019 | |
| cellular protein localization | GO:0034613 | 160 | 0.019 | |
| regulation of cellular protein metabolic process | GO:0032268 | 243 | 0.019 | |
| head development | GO:0060322 | 135 | 0.018 | |
| telomere maintenance | GO:0000723 | 21 | 0.018 | |
| positive regulation of signaling | GO:0023056 | 243 | 0.018 | |
| gene silencing by rna | GO:0031047 | 57 | 0.018 | |
| posttranscriptional gene silencing | GO:0016441 | 46 | 0.018 | |
| vesicle mediated transport | GO:0016192 | 381 | 0.018 | |
| single organism intracellular transport | GO:1902582 | 207 | 0.018 | |
| regulation of molecular function | GO:0065009 | 217 | 0.018 | |
| positive regulation of protein transport | GO:0051222 | 37 | 0.018 | |
| determination of adult lifespan | GO:0008340 | 137 | 0.017 | |
| regulation of innate immune response | GO:0045088 | 71 | 0.017 | |
| response to other organism | GO:0051707 | 293 | 0.017 | |
| defense response | GO:0006952 | 300 | 0.017 | |
| positive regulation of phosphate metabolic process | GO:0045937 | 139 | 0.017 | |
| regulation of intracellular transport | GO:0032386 | 64 | 0.017 | |
| ovarian follicle cell development | GO:0030707 | 248 | 0.017 | |
| dna repair | GO:0006281 | 54 | 0.017 | Human Yeast |
| regulation of cell cycle phase transition | GO:1901987 | 130 | 0.017 | |
| epithelial cell migration | GO:0010631 | 148 | 0.017 | |
| regulation of mitotic cell cycle | GO:0007346 | 190 | 0.017 | |
| protein processing | GO:0016485 | 68 | 0.017 | |
| respiratory system development | GO:0060541 | 213 | 0.017 | |
| regulation of establishment of protein localization | GO:0070201 | 61 | 0.017 | |
| retina development in camera type eye | GO:0060041 | 4 | 0.016 | |
| digestive system development | GO:0055123 | 149 | 0.016 | |
| protein import | GO:0017038 | 55 | 0.016 | |
| regulation of organ growth | GO:0046620 | 42 | 0.016 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 85 | 0.016 | |
| positive regulation of cellular amino acid metabolic process | GO:0045764 | 0 | 0.016 | |
| cell cycle dna replication | GO:0044786 | 23 | 0.016 | |
| response to glucose | GO:0009749 | 2 | 0.016 | |
| single organism behavior | GO:0044708 | 391 | 0.016 | |
| protein targeting | GO:0006605 | 64 | 0.016 | |
| positive regulation of heterochromatin assembly | GO:0031453 | 5 | 0.016 | |
| positive regulation of molecular function | GO:0044093 | 136 | 0.016 | |
| regulation of chromosome organization | GO:0033044 | 64 | 0.016 | |
| posttranscriptional gene silencing by rna | GO:0035194 | 45 | 0.016 | |
| protein transport | GO:0015031 | 155 | 0.016 | |
| columnar cuboidal epithelial cell differentiation | GO:0002065 | 256 | 0.016 | |
| mapk cascade | GO:0000165 | 107 | 0.016 | |
| regulation of phosphorylation | GO:0042325 | 147 | 0.016 | |
| nucleobase containing compound catabolic process | GO:0034655 | 165 | 0.016 | |
| leg disc morphogenesis | GO:0007478 | 80 | 0.016 | |
| nuclear transport | GO:0051169 | 72 | 0.015 | |
| cellular response to organic cyclic compound | GO:0071407 | 32 | 0.015 | |
| dna replication | GO:0006260 | 48 | 0.015 | Yeast |
| regulation of intracellular protein transport | GO:0033157 | 46 | 0.015 | |
| aging | GO:0007568 | 143 | 0.015 | |
| positive regulation of organelle organization | GO:0010638 | 65 | 0.015 | |
| heterocycle catabolic process | GO:0046700 | 166 | 0.015 | |
| mitotic nuclear division | GO:0007067 | 213 | 0.015 | |
| camera type eye development | GO:0043010 | 4 | 0.015 | |
| cellular response to organic substance | GO:0071310 | 132 | 0.015 | |
| proteolysis | GO:0006508 | 192 | 0.015 | |
| positive regulation of programmed cell death | GO:0043068 | 62 | 0.015 | |
| mrna cis splicing via spliceosome | GO:0045292 | 1 | 0.014 | |
| small gtpase mediated signal transduction | GO:0007264 | 88 | 0.014 | |
| histone methylation | GO:0016571 | 40 | 0.014 | |
| cell migration | GO:0016477 | 238 | 0.014 | |
| meiotic cell cycle | GO:0051321 | 171 | 0.014 | |
| pronuclear migration | GO:0035046 | 4 | 0.014 | |
| positive regulation of nucleocytoplasmic transport | GO:0046824 | 24 | 0.014 | |
| organic acid metabolic process | GO:0006082 | 103 | 0.014 | |
| regulation of chromatin modification | GO:1903308 | 28 | 0.014 | |
| regulation of catalytic activity | GO:0050790 | 185 | 0.014 | |
| regulation of cell shape | GO:0008360 | 113 | 0.014 | |
| multi multicellular organism process | GO:0044706 | 123 | 0.014 | |
| regulation of cytoplasmic transport | GO:1903649 | 47 | 0.014 | |
| positive regulation of intracellular protein transport | GO:0090316 | 30 | 0.014 | |
| regulation of ras protein signal transduction | GO:0046578 | 93 | 0.014 | |
| spinal cord development | GO:0021510 | 1 | 0.013 | |
| olfactory behavior | GO:0042048 | 97 | 0.013 | |
| actin cytoskeleton organization | GO:0030036 | 206 | 0.013 | |
| negative regulation of small gtpase mediated signal transduction | GO:0051058 | 13 | 0.013 | |
| epithelial tube morphogenesis | GO:0060562 | 88 | 0.013 | |
| purine nucleotide metabolic process | GO:0006163 | 146 | 0.013 | |
| appendage morphogenesis | GO:0035107 | 397 | 0.013 | |
| positive regulation of protein import into nucleus | GO:0042307 | 21 | 0.013 | |
| oxoacid metabolic process | GO:0043436 | 103 | 0.013 | |
| regulation of neural precursor cell proliferation | GO:2000177 | 35 | 0.013 | |
| regulation of cell differentiation | GO:0045595 | 302 | 0.013 | |
| response to temperature stimulus | GO:0009266 | 106 | 0.013 | |
| microtubule cytoskeleton organization involved in mitosis | GO:1902850 | 52 | 0.012 | |
| regulation of mitotic cell cycle phase transition | GO:1901990 | 130 | 0.012 | |
| nuclear dna replication | GO:0033260 | 1 | 0.012 | |
| regulation of protein deacetylation | GO:0090311 | 2 | 0.012 | |
| cellular macromolecule catabolic process | GO:0044265 | 136 | 0.012 | |
| cellular response to endogenous stimulus | GO:0071495 | 80 | 0.012 | |
| negative regulation of transferase activity | GO:0051348 | 18 | 0.012 | |
| regulation of cellular response to stress | GO:0080135 | 89 | 0.012 | |
| cytoplasmic transport | GO:0016482 | 130 | 0.012 | |
| methylation | GO:0032259 | 47 | 0.012 | |
| posttranscriptional regulation of gene expression | GO:0010608 | 145 | 0.012 | |
| mitotic spindle organization | GO:0007052 | 220 | 0.012 | |
| positive regulation of cellular protein metabolic process | GO:0032270 | 118 | 0.012 | |
| regulation of proteolysis | GO:0030162 | 87 | 0.012 | |
| negative regulation of mitotic cell cycle | GO:0045930 | 109 | 0.012 | |
| cytoskeleton dependent cytokinesis | GO:0061640 | 81 | 0.012 | |
| organophosphate metabolic process | GO:0019637 | 195 | 0.011 | |
| positive regulation of phosphorylation | GO:0042327 | 87 | 0.011 | |
| cellular amine metabolic process | GO:0044106 | 12 | 0.011 | |
| regulation of gene silencing | GO:0060968 | 63 | 0.011 | |
| imaginal disc derived appendage development | GO:0048737 | 399 | 0.011 | |
| leg disc development | GO:0035218 | 92 | 0.011 | |
| response to endogenous stimulus | GO:0009719 | 119 | 0.011 | |
| negative regulation of intracellular signal transduction | GO:1902532 | 57 | 0.011 | |
| reproductive system development | GO:0061458 | 74 | 0.011 | |
| negative regulation of signal transduction | GO:0009968 | 206 | 0.011 | |
| regulation of protein localization | GO:0032880 | 76 | 0.011 | |
| gene silencing by mirna | GO:0035195 | 22 | 0.011 | |
| dna recombination | GO:0006310 | 32 | 0.011 | Human |
| regulation of transcription by chromatin organization | GO:0034401 | 3 | 0.011 | |
| atp dependent chromatin remodeling | GO:0043044 | 22 | 0.010 | |
| carbohydrate metabolic process | GO:0005975 | 82 | 0.010 | |
| positive regulation of chromatin silencing | GO:0031937 | 16 | 0.010 | |
| response to dsrna | GO:0043331 | 15 | 0.010 | |
| regulation of intracellular signal transduction | GO:1902531 | 236 | 0.010 | |
| taxis | GO:0042330 | 304 | 0.010 | |
| camera type eye morphogenesis | GO:0048593 | 2 | 0.010 | |
| regulation of histone modification | GO:0031056 | 20 | 0.010 | |
| genitalia development | GO:0048806 | 26 | 0.010 | |
| eye photoreceptor cell development | GO:0042462 | 81 | 0.010 | |
| signal release | GO:0023061 | 49 | 0.010 | |
