Drosophila melanogaster

154 known processes

mus309 (Dmel_CG6920)

mutagen-sensitive 309

(Aliases: mus 309,blm,Dmblm,DmKu70,CG6920,Dmel\CG6920,Blm,MUS309,Ku70,DmBlm,RecQ,mus309/DmBLM,DmBLM)

mus309 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
double strand break repair via nonhomologous end joiningGO:000630350.869
non recombinational repairGO:000072670.819
double strand break repairGO:0006302260.727
mitotic g2 m transition checkpointGO:0044818700.688
Human
double strand break repair via synthesis dependent strand annealingGO:004500360.649
g2 dna damage checkpointGO:0031572690.593
Human
cell divisionGO:00513012480.575
Human
nucleobase containing compound catabolic processGO:00346551650.514
negative regulation of cell cycleGO:00457861160.437
Human
negative regulation of cell cycle phase transitionGO:19019881030.435
Human
dna synthesis involved in dna repairGO:000073150.359
mitotic g2 dna damage checkpointGO:0007095690.322
Human
negative regulation of cell cycle g2 m phase transitionGO:190275080.289
negative regulation of cell cycle processGO:00109481090.273
Human
mitotic dna damage checkpointGO:0044773740.271
Human
dna integrity checkpointGO:0031570810.257
Human Worm
meiosis iGO:0007127590.241
regulation of cell cycle phase transitionGO:19019871300.237
Human
negative regulation of mitotic cell cycleGO:00459301090.235
Human
meiotic cell cycle processGO:19030461320.221
dna repairGO:0006281540.207
double strand break repair via homologous recombinationGO:0000724130.191
meiotic chromosome segregationGO:0045132590.189
Worm
mitotic dna integrity checkpointGO:0044774750.176
Human
dna recombinationGO:0006310320.174
organic cyclic compound catabolic processGO:19013611680.172
cellular catabolic processGO:00442483720.171
negative regulation of macromolecule biosynthetic processGO:00105582700.169
response to abiotic stimulusGO:00096283410.167
Human Worm
cellular response to dna damage stimulusGO:00069742230.159
female meiotic divisionGO:0007143700.159
deathGO:00162652840.157
Mouse Worm
catabolic processGO:00090564090.151
dna double strand break processingGO:000072930.150
Human
negative regulation of g2 m transition of mitotic cell cycleGO:001097280.145
regulation of dna repairGO:000628250.143
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.138
aromatic compound catabolic processGO:00194391660.134
regulation of cell differentiationGO:00455953020.133
positive regulation of macromolecule metabolic processGO:00106044050.133
Human
negative regulation of cellular biosynthetic processGO:00313272770.132
cell cycle phase transitionGO:00447701400.126
Human
cellular nitrogen compound catabolic processGO:00442701650.124
dna damage checkpointGO:0000077780.119
Human Worm
regulation of cell cycleGO:00517262910.110
Human
regulation of multicellular organismal developmentGO:20000264140.110
positive regulation of transcription dna templatedGO:00458932660.106
Human
regulation of cellular protein metabolic processGO:00322682430.106
Human
positive regulation of nitrogen compound metabolic processGO:00511733540.102
Human
reciprocal dna recombinationGO:0035825190.099
mrna metabolic processGO:00160711240.099
mrna processingGO:00063971040.096
response to organic substanceGO:00100332840.095
Human
macromolecule catabolic processGO:00090571610.093
Human
mitotic recombinationGO:000631220.089
Mouse
positive regulation of nucleobase containing compound metabolic processGO:00459353320.088
Human
regulation of cell cycle processGO:00105641810.086
Human
response to ionizing radiationGO:0010212320.086
Human Worm
positive regulation of macromolecule biosynthetic processGO:00105572830.085
Human
nuclear transcribed mrna catabolic processGO:0000956240.084
positive regulation of rna biosynthetic processGO:19026802660.083
Human
mitotic cell cycle checkpointGO:0007093880.082
Human
small molecule metabolic processGO:00442813050.080
positive regulation of rna metabolic processGO:00512542710.078
Human
regulation of protein metabolic processGO:00512462560.078
Human
asymmetric cell divisionGO:0008356370.077
response to alkaloidGO:0043279260.075
Human
translesion synthesisGO:001998520.072
cell cycle checkpointGO:0000075950.072
Human Worm
telomere maintenance via recombinationGO:000072210.071
response to radiationGO:00093141550.069
Human Worm
regulation of mitotic cell cycle phase transitionGO:19019901300.068
Human
positive regulation of biosynthetic processGO:00098913160.068
Human
regulation of mitotic cell cycleGO:00073461900.068
Human
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.068
nucleotide excision repairGO:000628980.067
recombinational repairGO:0000725130.067
regulation of double strand break repairGO:200077930.064
chromosome segregationGO:00070591570.064
Worm
postreplication repairGO:000630120.064
rna processingGO:00063961470.064
regulation of embryonic developmentGO:0045995680.063
rna catabolic processGO:0006401370.062
mitotic cell cycle phase transitionGO:00447721380.060
Human
transcription from rna polymerase ii promoterGO:00063663680.059
organelle fissionGO:00482853400.059
protein modification processGO:00362114380.058
Human
regulation of i kappab kinase nf kappab signalingGO:004312220.055
protein complex assemblyGO:00064612000.055
Human
regulation of transcription from rna polymerase ii promoterGO:00063573780.055
positive regulation of cellular biosynthetic processGO:00313283160.055
Human
positive regulation of catabolic processGO:00098961050.055
cellular response to abiotic stimulusGO:0071214580.055
Human
cellular protein modification processGO:00064644380.054
Human
female meiosis chromosome segregationGO:0016321330.053
retina development in camera type eyeGO:006004140.053
organic substance catabolic processGO:19015753080.053
negative regulation of mitotic cell cycle phase transitionGO:19019911030.052
Human
programmed cell deathGO:00125012570.051
Mouse Worm
positive regulation of nucleic acid templated transcriptionGO:19035082660.050
Human
nucleobase containing small molecule metabolic processGO:00550861740.049
macromolecular complex assemblyGO:00650032560.049
Human
regulation of cell developmentGO:00602842150.048
mrna catabolic processGO:0006402330.048
response to monosaccharideGO:003428440.046
single organism biosynthetic processGO:00447112060.045
regulation of nervous system developmentGO:00519602480.044
transmembrane transportGO:00550851390.044
purine nucleoside metabolic processGO:00422781270.043
organonitrogen compound metabolic processGO:19015643180.043
positive regulation of nervous system developmentGO:0051962690.043
organophosphate metabolic processGO:00196371950.043
anatomical structure homeostasisGO:0060249970.042
Mouse
negative regulation of cellular metabolic processGO:00313243820.042
maintenance of locationGO:0051235730.042
ribonucleoside monophosphate catabolic processGO:0009158390.041
telomere organizationGO:0032200210.041
Mouse
homeostatic processGO:00425921990.041
Mouse
camera type eye developmentGO:004301040.040
nuclear transcribed mrna catabolic process deadenylation dependent decayGO:0000288140.040
g2 m transition of mitotic cell cycleGO:0000086190.040
purine containing compound catabolic processGO:00725231120.040
ribonucleoside triphosphate metabolic processGO:00091991190.039
carboxylic acid metabolic processGO:0019752920.039
posttranscriptional regulation of gene expressionGO:00106081450.039
humoral immune responseGO:00069591170.038
heterocycle catabolic processGO:00467001660.038
positive regulation of cellular catabolic processGO:0031331950.037
retrograde axon cargo transportGO:000809090.037
protein phosphorylationGO:00064681690.036
Human
response to anestheticGO:007234790.036
dorsal ventral pattern formationGO:00099531330.036
negative regulation of biosynthetic processGO:00098902770.036
chromosome organizationGO:00512763600.035
Mouse Worm
long term memoryGO:0007616620.035
cell cycle g2 m phase transitionGO:0044839220.034
positive regulation of developmental processGO:00510941430.034
positive regulation of cell communicationGO:00106472500.034
positive regulation of multicellular organismal processGO:00512401430.033
organic acid metabolic processGO:00060821030.033
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280230.033
purine ribonucleoside metabolic processGO:00461281270.033
negative regulation of gene expressionGO:00106293870.033
regulation of meiosisGO:004002030.033
mrna 3 end processingGO:0031124280.033
ribose phosphate metabolic processGO:00196931450.032
apoptotic processGO:00069151590.032
Mouse Worm
negative regulation of response to stimulusGO:00485852580.032
positive regulation of endopeptidase activityGO:0010950260.032
oxoacid metabolic processGO:00434361030.032
endocytosisGO:00068973100.031
molting cycle chitin based cuticleGO:0007591560.031
cell proliferationGO:00082832990.031
Mouse
positive regulation of signalingGO:00230562430.031
regulation of transportGO:00510491810.031
positive regulation of response to stimulusGO:00485843230.031
ion transportGO:00068111450.030
regulation of neurogenesisGO:00507671580.030
regulation of nuclear transcribed mrna poly a tail shorteningGO:006021140.030
positive regulation of cysteine type endopeptidase activityGO:2001056240.030
kidney morphogenesisGO:006099330.029
nucleoside metabolic processGO:00091161270.029
negative regulation of cell divisionGO:0051782170.029
Human
response to caffeineGO:0031000120.028
regionalizationGO:00030024160.028
response to drugGO:0042493170.028
sensory organ morphogenesisGO:00905962600.028
reciprocal meiotic recombinationGO:0007131190.028
lipid storageGO:0019915380.027
ribonucleoside catabolic processGO:00424541120.027
dna biosynthetic processGO:0071897240.027
phosphorylationGO:00163102940.027
Human
regulation of dna recombinationGO:000001840.026
Human Mouse
signal transduction in response to dna damageGO:004277030.026
epithelial cell developmentGO:00020642740.026
carbohydrate derivative metabolic processGO:19011352170.026
telomere maintenanceGO:0000723210.026
Mouse
positive regulation of signal transductionGO:00099672230.026
meiotic cell cycleGO:00513211710.026
cellular response to radiationGO:0071478520.026
Human
regulation of cell deathGO:00109411730.026
Mouse Worm
negative regulation of signal transductionGO:00099682060.026
regulation of intracellular signal transductionGO:19025312360.026
regulation of cell divisionGO:0051302720.025
Human
vesicle mediated transportGO:00161923810.025
mitotic cell cycle embryonicGO:0045448380.025
cell deathGO:00082192790.025
Mouse Worm
cellular amino acid metabolic processGO:0006520610.025
regulation of cellular response to stressGO:0080135890.025
cellular response to chemical stimulusGO:00708871990.025
Human
negative regulation of cell communicationGO:00106482230.025
cellular macromolecule catabolic processGO:00442651360.024
Human
regulation of epithelial cell differentiationGO:003085640.024
organonitrogen compound catabolic processGO:19015651280.024
metal ion transportGO:0030001740.023
cellular macromolecular complex assemblyGO:00346221530.023
meiotic nuclear divisionGO:00071261510.023
digestive tract developmentGO:00485651490.023
purine nucleotide metabolic processGO:00061631460.022
regulation of localizationGO:00328792750.022
purine containing compound metabolic processGO:00725211550.022
immune system processGO:00023763470.022
Mouse
regulation of cellular ketone metabolic processGO:001056530.022
male gamete generationGO:00482322010.021
dorsal ventral axis specificationGO:0009950660.021
atp metabolic processGO:0046034490.021
compound eye morphogenesisGO:00017452490.021
body morphogenesisGO:001017120.021
embryo development ending in birth or egg hatchingGO:00097921520.021
positive regulation of catalytic activityGO:00430851180.021
regulation of catalytic activityGO:00507901850.021
Human
regulation of cellular catabolic processGO:00313291570.021
rna localizationGO:00064031150.020
nucleoside phosphate metabolic processGO:00067531620.020
dna geometric changeGO:0032392160.020
regulation of organelle organizationGO:00330431960.020
cellular amine metabolic processGO:0044106120.020
positive regulation of epithelial cell differentiationGO:003085810.020
negative regulation of multicellular organismal processGO:00512411420.020
regulation of peptidase activityGO:0052547390.020
positive regulation of intracellular signal transductionGO:19025331160.020
regulation of multi organism processGO:00439001310.020
gastrulationGO:0007369700.019
positive regulation of cell differentiationGO:0045597640.019
positive regulation of protein metabolic processGO:00512471280.019
regulation of mrna metabolic processGO:1903311720.019
cytokinesisGO:0000910900.019
male meiosis chromosome segregationGO:0007060100.019
response to oxygen containing compoundGO:19017002000.019
Human
positive regulation of gene expressionGO:00106282900.019
Human
regulation of hydrolase activityGO:0051336970.019
stress activated mapk cascadeGO:0051403520.018
negative regulation of cell differentiationGO:00455961430.018
secretionGO:00469031090.018
response to other organismGO:00517072930.018
purine nucleoside catabolic processGO:00061521120.018
eye developmentGO:00016543230.018
germarium derived oocyte fate determinationGO:0007294260.018
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630110.018
regulation of cellular amine metabolic processGO:003323830.018
spermatogenesisGO:00072832000.017
cellular response to ionizing radiationGO:0071479150.017
Human
synaptic transmissionGO:00072682880.017
lipid localizationGO:0010876540.017
nucleoside triphosphate metabolic processGO:00091411200.017
regulation of organ morphogenesisGO:2000027780.017
regulation of nuclear divisionGO:0051783580.017
positive regulation of cell sizeGO:0045793210.017
positive regulation of apoptotic processGO:0043065470.016
catechol containing compound biosynthetic processGO:000971330.016
mrna splicing via spliceosomeGO:0000398730.016
posttranscriptional gene silencing by rnaGO:0035194450.016
mitotic dna replication checkpointGO:003331450.016
regulation of alternative mrna splicing via spliceosomeGO:0000381600.016
negative regulation of cell proliferationGO:0008285690.016
rna 3 end processingGO:0031123450.016
actin filament based processGO:00300292200.016
ribonucleoside triphosphate catabolic processGO:00092031080.016
protein localizationGO:00081042840.016
organophosphate catabolic processGO:00464341120.016
response to organonitrogen compoundGO:0010243750.016
Human
positive regulation of neurogenesisGO:0050769410.016
amine metabolic processGO:0009308120.016
regulation of synaptic transmissionGO:0050804690.016
negative regulation of signalingGO:00230572190.016
carbohydrate metabolic processGO:0005975820.016
regulation of cysteine type endopeptidase activityGO:2000116270.015
positive regulation of i kappab kinase nf kappab signalingGO:004312310.015
ion transmembrane transportGO:00342201220.015
purine ribonucleoside catabolic processGO:00461301120.015
glycosyl compound metabolic processGO:19016571270.015
regulation of phosphorus metabolic processGO:00511742100.015
Human
establishment of localization in cellGO:00516494020.015
organelle assemblyGO:00709251980.015
positive regulation of proteolysisGO:0045862520.015
regulation of mrna catabolic processGO:006101350.015
negative regulation of translationGO:0017148280.015
positive regulation of peptidase activityGO:0010952290.015
alternative mrna splicing via spliceosomeGO:0000380600.015
regulation of mrna processingGO:0050684710.014
positive regulation of cellular amino acid metabolic processGO:004576400.014
anion transmembrane transportGO:0098656260.014
alpha amino acid metabolic processGO:1901605200.014
regulation of anatomical structure sizeGO:00900661630.014
regulation of autophagyGO:0010506620.014
cell agingGO:000756920.014
organic substance transportGO:00717022570.014
negative regulation of nervous system developmentGO:0051961920.014
oocyte fate determinationGO:0030716270.014
nuclear divisionGO:00002803320.014
regulation of response to dna damage stimulusGO:2001020230.014
regulation of apoptotic processGO:00429811300.014
Mouse Worm
enzyme linked receptor protein signaling pathwayGO:00071671790.014
regulation of response to biotic stimulusGO:0002831630.013
intracellular mrna localizationGO:0008298660.013
cellular response to mechanical stimulusGO:007126020.013
jnk cascadeGO:0007254500.013
regulation of pole plasm oskar mrna localizationGO:0007317270.013
single organism carbohydrate metabolic processGO:0044723720.013
positive regulation of cellular amine metabolic processGO:003324000.013
purine ribonucleotide catabolic processGO:00091541090.013
regulation of cell maturationGO:1903429270.013
cellular response to gamma radiationGO:0071480100.013
forebrain developmentGO:003090020.013
negative regulation of developmental growthGO:0048640640.013
antimicrobial humoral responseGO:0019730990.013
regulation of g2 m transition of mitotic cell cycleGO:0010389150.013
purine nucleoside monophosphate catabolic processGO:0009128380.013
regulation of endopeptidase activityGO:0052548360.013
negative regulation of nucleobase containing compound metabolic processGO:00459342610.013
dna metabolic processGO:00062592270.013
regulation of cell proliferationGO:00421271630.012
Mouse
regulation of stress activated mapk cascadeGO:0032872410.012
single organism behaviorGO:00447083910.012
negative regulation of rna metabolic processGO:00512532510.012
nitrogen compound transportGO:0071705850.012
response to oxidative stressGO:0006979860.012
developmental growthGO:00485892800.012
regulation of protein complex assemblyGO:0043254420.012
response to nitrogen compoundGO:1901698900.012
Human
regulation of cellular amino acid metabolic processGO:000652100.012
protein catabolic processGO:00301631010.012
regulation of oocyte developmentGO:0060281270.012
regulation of rna splicingGO:0043484690.012
regulation of catabolic processGO:00098941700.012
regulation of nf kappab import into nucleusGO:004234510.012
response to ethanolGO:0045471590.012
male meiosis cytokinesisGO:0007112260.012
cellular homeostasisGO:0019725800.012
regulation of phosphorylationGO:00423251470.011
Human
production of molecular mediator of immune responseGO:0002440460.011
primary amino compound metabolic processGO:190116020.011
cellular response to organic substanceGO:00713101320.011
Human
regulation of protein modification processGO:00313991120.011
Human
purine ribonucleotide metabolic processGO:00091501450.011
regulation of cellular component sizeGO:0032535980.011
rna splicingGO:0008380830.011
ribonucleotide catabolic processGO:00092611090.011
negative regulation of developmental processGO:00510932010.011
regulation of jnk cascadeGO:0046328400.011
positive regulation of molecular functionGO:00440931360.011
learning or memoryGO:00076111410.011
epithelial cell differentiationGO:00308553220.011
nucleotide metabolic processGO:00091171610.011
autophagyGO:00069141080.011
appendage morphogenesisGO:00351073970.011
cellular protein complex assemblyGO:0043623710.011
wnt signaling pathwayGO:0016055980.011
glycosyl compound catabolic processGO:19016581120.011
negative regulation of rna biosynthetic processGO:19026792400.011
response to paraquatGO:190156240.011
response to light stimulusGO:00094161240.011
dorsal closureGO:0007391790.011
response to decreased oxygen levelsGO:0036293580.011
purine ribonucleoside triphosphate catabolic processGO:00092071080.011
mesenchymal cell developmentGO:001403110.011
regulation of epithelial cell proliferationGO:005067840.011
regulation of cellular component biogenesisGO:00440872010.011
negative regulation of growthGO:0045926840.011
cellular macromolecule localizationGO:00707272200.011
regulation of molecular functionGO:00650092170.011
Human Mouse
positive regulation of synaptic growth at neuromuscular junctionGO:0045887260.010
cation transportGO:00068121100.010
anterior posterior axis specificationGO:00099481090.010
regulation of stress activated protein kinase signaling cascadeGO:0070302420.010
establishment or maintenance of microtubule cytoskeleton polarityGO:0030951410.010
regulation of photoreceptor cell differentiationGO:0046532340.010
cell motilityGO:00488702510.010
regulation of ion transportGO:0043269390.010
polarity specification of dorsal ventral axisGO:000995160.010
actin cytoskeleton organizationGO:00300362060.010
regulation of mrna 3 end processingGO:003144070.010
stress activated protein kinase signaling cascadeGO:0031098550.010
response to hypoxiaGO:0001666530.010
response to external biotic stimulusGO:00432072930.010
positive regulation of hydrolase activityGO:0051345780.010
carbohydrate derivative biosynthetic processGO:1901137850.010
negative regulation of meiotic cell cycleGO:005144720.010
cuticle developmentGO:0042335860.010

mus309 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.046
cancerDOID:16200.046
thoracic cancerDOID:509300.041
organ system cancerDOID:005068600.041
disease of anatomical entityDOID:700.016
breast cancerDOID:161200.015
bone diseaseDOID:008000100.013
connective tissue diseaseDOID:6500.013
musculoskeletal system diseaseDOID:1700.013
male reproductive organ cancerDOID:385600.011
reproductive organ cancerDOID:19300.011