IMP: Integrative Multi-species Prediction

Drosophila melanogaster

140 known processes

kuz (Dmel_CG7147)

kuzbanian

(Aliases: 11410,Dmel\CG7147,CG7147,l(2)k01403,Kuz,br38,l(2)03782,BG:DS07660.3,34Da,l(2)c00136,l(2)34Da,ADAM10,GS11410,l34Da,l(2)br38,CT22079)

FLYBASE: FBgn0259984
Entrez: 34772
UniProtKB: A8DZ02
UniProtKB: Q9VJW9
UniProtKB: Q59DZ3
UniProtKB: A8DZ03

Process Predictions
Disease Predictions

kuz biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
ovarian follicle cell migration	GO:0007297	121	0.998
cell migration	GO:0016477	238	0.997
epithelium migration	GO:0090132	148	0.993
axon development	GO:0061564	297	0.993
appendage morphogenesis	GO:0035107	397	0.992
localization of cell	GO:0051674	257	0.992
heart development	GO:0007507	82	0.988
cell motility	GO:0048870	251	0.983
border follicle cell migration	GO:0007298	113	0.979
epithelial cell migration	GO:0010631	148	0.975
axonogenesis	GO:0007409	290	0.973
epithelial cell development	GO:0002064	274	0.956
tissue migration	GO:0090130	155	0.945
actin filament organization	GO:0007015	126	0.940
columnar cuboidal epithelial cell differentiation	GO:0002065	256	0.931
imaginal disc derived wing morphogenesis	GO:0007476	337	0.931
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.930
ovarian follicle cell development	GO:0030707	248	0.916
notch signaling pathway	GO:0007219	120	0.913
regulation of notch signaling pathway	GO:0008593	100	0.897
neuron projection guidance	GO:0097485	241	0.896
axon guidance	GO:0007411	233	0.888
regulation of cell development	GO:0060284	215	0.872
cell proliferation	GO:0008283	299	0.871
lateral inhibition	GO:0046331	206	0.866
post embryonic appendage morphogenesis	GO:0035120	385	0.865
ameboidal type cell migration	GO:0001667	151	0.864
forebrain development	GO:0030900	2	0.839
muscle structure development	GO:0061061	224	0.821
epithelial cell differentiation	GO:0030855	322	0.809
head development	GO:0060322	135	0.805
appendage development	GO:0048736	401	0.804
regulation of cell differentiation	GO:0045595	302	0.804
wing disc morphogenesis	GO:0007472	344	0.802
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.785
dendrite morphogenesis	GO:0048813	199	0.778
actin cytoskeleton organization	GO:0030036	206	0.728
regulation of growth	GO:0040008	233	0.708
cell projection assembly	GO:0030031	94	0.687
imaginal disc derived appendage development	GO:0048737	399	0.687
glial cell development	GO:0021782	27	0.681
regulation of axonogenesis	GO:0050770	32	0.678
epidermal cell differentiation	GO:0009913	51	0.673
adult behavior	GO:0030534	137	0.666
muscle cell differentiation	GO:0042692	103	0.651
gliogenesis	GO:0042063	80	0.635
regulation of neurogenesis	GO:0050767	158	0.618
heart morphogenesis	GO:0003007	32	0.618
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.616
glial cell migration	GO:0008347	31	0.614
r7 cell differentiation	GO:0045466	43	0.606
neuron fate commitment	GO:0048663	50	0.583
syncytium formation	GO:0006949	43	0.576
positive regulation of transcription dna templated	GO:0045893	266	0.566
photoreceptor cell differentiation	GO:0046530	170	0.565
tube development	GO:0035295	244	0.564
eye photoreceptor cell differentiation	GO:0001754	145	0.558
striated muscle cell differentiation	GO:0051146	90	0.554
tube morphogenesis	GO:0035239	191	0.552
compound eye photoreceptor cell differentiation	GO:0001751	140	0.551
cell fate specification	GO:0001708	71	0.533
regulation of nervous system development	GO:0051960	248	0.527
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.527
sensory perception	GO:0007600	196	0.526
regulation of r7 cell differentiation	GO:0045676	15	0.520
open tracheal system development	GO:0007424	204	0.518
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.508
intracellular signal transduction	GO:0035556	300	0.507
circulatory system development	GO:0072359	82	0.504
digestive tract morphogenesis	GO:0048546	127	0.503
columnar cuboidal epithelial cell development	GO:0002066	249	0.500
regulation of multicellular organismal development	GO:2000026	414	0.499
hair cell differentiation	GO:0035315	47	0.499
regionalization	GO:0003002	416	0.491
regulation of phosphate metabolic process	GO:0019220	210	0.488
regulation of neuron differentiation	GO:0045664	103	0.484
negative regulation of developmental process	GO:0051093	201	0.479
positive regulation of signal transduction	GO:0009967	223	0.476
cell death	GO:0008219	279	0.476
skin development	GO:0043588	65	0.467
actin filament based process	GO:0030029	220	0.467
regulation of molecular function	GO:0065009	217	0.460
hindgut morphogenesis	GO:0007442	58	0.457
multicellular organismal reproductive behavior	GO:0033057	110	0.457
regulation of cell morphogenesis	GO:0022604	163	0.445
regulation of localization	GO:0032879	275	0.440
programmed cell death	GO:0012501	257	0.432
negative regulation of multicellular organismal process	GO:0051241	142	0.428
death	GO:0016265	284	0.419
cell fate determination	GO:0001709	91	0.418
neuroblast fate determination	GO:0007400	12	0.404
peripheral nervous system development	GO:0007422	52	0.392
striated muscle cell development	GO:0055002	50	0.391
reproductive behavior	GO:0019098	122	0.390
muscle cell development	GO:0055001	50	0.386
cardiovascular system development	GO:0072358	82	0.377
regulation of catalytic activity	GO:0050790	185	0.377
synapse assembly	GO:0007416	143	0.372
telencephalon development	GO:0021537	2	0.360
tissue morphogenesis	GO:0048729	297	0.358
cell adhesion	GO:0007155	136	0.350
regulation of neuroblast proliferation	GO:1902692	34	0.346
cellular ketone metabolic process	GO:0042180	24	0.337
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.335
protein modification process	GO:0036211	438	0.334
positive regulation of rna biosynthetic process	GO:1902680	266	0.323
positive regulation of hydrolase activity	GO:0051345	78	0.312
response to oxygen containing compound	GO:1901700	200	0.310
immune system process	GO:0002376	347	0.306
positive regulation of catabolic process	GO:0009896	105	0.303
small molecule metabolic process	GO:0044281	305	0.291
negative regulation of notch signaling pathway	GO:0045746	41	0.289
central nervous system development	GO:0007417	201	0.286
sensory organ morphogenesis	GO:0090596	260	0.284
lamellipodium organization	GO:0097581	21	0.283
ras protein signal transduction	GO:0007265	88	0.283
gland development	GO:0048732	191	0.280
kidney epithelium development	GO:0072073	3	0.279
cellular component assembly involved in morphogenesis	GO:0010927	151	0.277
eye development	GO:0001654	323	0.274
dorsal ventral axon guidance	GO:0033563	2	0.273
epithelial cell migration open tracheal system	GO:0007427	32	0.272
adult locomotory behavior	GO:0008344	76	0.269
axon midline choice point recognition	GO:0016199	26	0.268
response to abiotic stimulus	GO:0009628	341	0.264
neuroblast proliferation	GO:0007405	74	0.261
glial cell differentiation	GO:0010001	35	0.261
response to other organism	GO:0051707	293	0.259
germarium derived egg chamber formation	GO:0007293	101	0.259
mushroom body development	GO:0016319	70	0.257
positive regulation of axon extension	GO:0045773	2	0.256
rhythmic process	GO:0048511	106	0.255
positive regulation of molecular function	GO:0044093	136	0.252
endosomal transport	GO:0016197	44	0.246
taxis	GO:0042330	304	0.240
hematopoietic or lymphoid organ development	GO:0048534	57	0.238
positive regulation of synaptic growth at neuromuscular junction	GO:0045887	26	0.236
regulation of photoreceptor cell differentiation	GO:0046532	34	0.235
compound eye development	GO:0048749	307	0.234
organonitrogen compound metabolic process	GO:1901564	318	0.230
dendrite guidance	GO:0070983	21	0.229
morphogenesis of an epithelium	GO:0002009	276	0.228
ribonucleotide catabolic process	GO:0009261	109	0.227
dendrite development	GO:0016358	204	0.226
establishment of imaginal disc derived wing hair orientation	GO:0001737	24	0.226
neuroblast division	GO:0055057	35	0.225
catabolic process	GO:0009056	409	0.224
cell cell signaling involved in cell fate commitment	GO:0045168	210	0.219
homeostatic process	GO:0042592	199	0.219
ventral cord development	GO:0007419	16	0.218
stem cell differentiation	GO:0048863	117	0.216
locomotory behavior	GO:0007626	176	0.214
epidermis development	GO:0008544	65	0.213
negative regulation of response to stimulus	GO:0048585	258	0.212
axon ensheathment in central nervous system	GO:0032291	3	0.209
positive regulation of response to stimulus	GO:0048584	323	0.207
regulation of cellular catabolic process	GO:0031329	157	0.204
regulation of phosphorus metabolic process	GO:0051174	210	0.203
nephron tubule development	GO:0072080	3	0.202
mesoderm development	GO:0007498	78	0.200
response to external biotic stimulus	GO:0043207	293	0.200
regulation of anatomical structure morphogenesis	GO:0022603	242	0.197
renal system development	GO:0072001	72	0.197
morphogenesis of embryonic epithelium	GO:0016331	94	0.196
nuclear division	GO:0000280	332	0.195
positive regulation of macromolecule metabolic process	GO:0010604	405	0.193
regulation of dendrite morphogenesis	GO:0048814	28	0.193
regulation of intracellular signal transduction	GO:1902531	236	0.192
positive regulation of rna metabolic process	GO:0051254	271	0.191
transcription from rna polymerase ii promoter	GO:0006366	368	0.185
vesicle mediated transport	GO:0016192	381	0.183
endocytosis	GO:0006897	310	0.181
embryonic morphogenesis	GO:0048598	206	0.181
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.180
chemotaxis	GO:0006935	249	0.179
developmental maturation	GO:0021700	172	0.179
positive regulation of filopodium assembly	GO:0051491	15	0.178
formation of organ boundary	GO:0010160	30	0.177
multi multicellular organism process	GO:0044706	123	0.177
hindbrain development	GO:0030902	2	0.176
negative regulation of gene expression	GO:0010629	387	0.172
regulation of neuron projection development	GO:0010975	69	0.170
regulation of developmental growth	GO:0048638	174	0.169
response to mechanical stimulus	GO:0009612	28	0.169
regulation of transport	GO:0051049	181	0.166
regulation of catabolic process	GO:0009894	170	0.165
stem cell fate commitment	GO:0048865	25	0.165
small gtpase mediated signal transduction	GO:0007264	88	0.164
larval development	GO:0002164	104	0.163
filopodium assembly	GO:0046847	33	0.163
regulation of cell projection organization	GO:0031344	92	0.162
single organism cellular localization	GO:1902580	180	0.159
cellular protein modification process	GO:0006464	438	0.159
positive regulation of nervous system development	GO:0051962	69	0.157
compound eye morphogenesis	GO:0001745	249	0.156
regulation of hydrolase activity	GO:0051336	97	0.156
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.155
positive regulation of phosphorus metabolic process	GO:0010562	139	0.155
multi organism behavior	GO:0051705	175	0.153
developmental growth	GO:0048589	280	0.153
peptidyl amino acid modification	GO:0018193	105	0.151
nucleobase containing small molecule metabolic process	GO:0055086	174	0.151
nephron tubule morphogenesis	GO:0072078	3	0.150
cell maturation	GO:0048469	144	0.146
renal tubule morphogenesis	GO:0061333	44	0.144
ribonucleoside triphosphate metabolic process	GO:0009199	119	0.144
glial cell fate commitment	GO:0021781	3	0.143
eye morphogenesis	GO:0048592	260	0.141
compound eye photoreceptor development	GO:0042051	78	0.138
positive regulation of nucleoside metabolic process	GO:0045979	47	0.138
imaginal disc derived wing hair organization	GO:0035317	45	0.137
regulation of organelle organization	GO:0033043	196	0.136
stem cell proliferation	GO:0072089	88	0.134
regulation of cell death	GO:0010941	173	0.133
axonal fasciculation	GO:0007413	12	0.132
regulation of programmed cell death	GO:0043067	152	0.131
reproductive system development	GO:0061458	74	0.131
positive regulation of multicellular organismal process	GO:0051240	143	0.130
negative regulation of nervous system development	GO:0051961	92	0.130
multi organism reproductive behavior	GO:0044705	121	0.129
organelle fission	GO:0048285	340	0.128
regulation of neural precursor cell proliferation	GO:2000177	35	0.128
mesenchymal cell differentiation	GO:0048762	1	0.127
embryonic organ development	GO:0048568	50	0.127
cellular response to external stimulus	GO:0071496	66	0.126
positive regulation of cellular protein metabolic process	GO:0032270	118	0.125
response to organic substance	GO:0010033	284	0.123
germarium derived female germ line cyst formation	GO:0030727	42	0.123
regulation of cell projection assembly	GO:0060491	30	0.123
imaginal disc derived wing hair site selection	GO:0035320	4	0.121
germ line cyst formation	GO:0048134	44	0.121
semaphorin plexin signaling pathway	GO:0071526	4	0.120
biological adhesion	GO:0022610	138	0.120
positive regulation of cell migration	GO:0030335	2	0.120
g protein coupled receptor signaling pathway	GO:0007186	136	0.119
positive regulation of r7 cell differentiation	GO:0045678	7	0.118
purine nucleoside triphosphate metabolic process	GO:0009144	119	0.117
regulation of protein localization	GO:0032880	76	0.117
camera type eye development	GO:0043010	4	0.116
nucleoside metabolic process	GO:0009116	127	0.116
positive regulation of developmental process	GO:0051094	143	0.114
purine ribonucleotide catabolic process	GO:0009154	109	0.113
mating behavior	GO:0007617	106	0.111
negative regulation of cell differentiation	GO:0045596	143	0.110
protein modification by small protein conjugation	GO:0032446	79	0.109
chaeta development	GO:0022416	97	0.109
axon choice point recognition	GO:0016198	26	0.107
chorion containing eggshell formation	GO:0007304	105	0.105
cellular cation homeostasis	GO:0030003	38	0.103
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.103
retina development in camera type eye	GO:0060041	4	0.102
regulation of cellular component size	GO:0032535	98	0.101
oviposition	GO:0018991	19	0.101
tissue homeostasis	GO:0001894	36	0.101
epithelial tube morphogenesis	GO:0060562	88	0.100
hemocyte differentiation	GO:0042386	38	0.100
formation of anatomical boundary	GO:0048859	37	0.098
cranial nerve development	GO:0021545	1	0.096
neuron recognition	GO:0008038	101	0.096
positive regulation of gtpase activity	GO:0043547	43	0.096
chaeta morphogenesis	GO:0008407	42	0.095
cell division	GO:0051301	248	0.094
growth	GO:0040007	359	0.092
female germ line cyst formation	GO:0048135	42	0.092
hemopoiesis	GO:0030097	46	0.092
regulation of cytoskeleton organization	GO:0051493	89	0.091
leg disc morphogenesis	GO:0007478	80	0.091
kidney development	GO:0001822	3	0.091
brain development	GO:0007420	120	0.090
imaginal disc derived leg morphogenesis	GO:0007480	80	0.090
regulation of synapse assembly	GO:0051963	94	0.090
pharynx development	GO:0060465	1	0.090
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	119	0.089
positive regulation of ras gtpase activity	GO:0032320	36	0.089
positive regulation of intracellular signal transduction	GO:1902533	116	0.088
mating	GO:0007618	120	0.088
regulation of actin filament polymerization	GO:0030833	25	0.088
positive regulation of actin filament polymerization	GO:0030838	11	0.088
positive regulation of cell proliferation	GO:0008284	47	0.087
positive regulation of cellular catabolic process	GO:0031331	95	0.087
positive regulation of purine nucleotide catabolic process	GO:0033123	46	0.087
segment specification	GO:0007379	33	0.086
actin filament bundle organization	GO:0061572	28	0.085
regulation of lamellipodium organization	GO:1902743	15	0.085
positive regulation of proteasomal ubiquitin dependent protein catabolic process	GO:0032436	19	0.085
cell recognition	GO:0008037	102	0.085
positive regulation of axonogenesis	GO:0050772	2	0.085
organic substance catabolic process	GO:1901575	308	0.085
positive regulation of cell communication	GO:0010647	250	0.084
regulation of immune system process	GO:0002682	176	0.083
actin filament polymerization	GO:0030041	27	0.082
neuron maturation	GO:0042551	31	0.081
regulation of phosphorylation	GO:0042325	147	0.081
negative regulation of transcription dna templated	GO:0045892	237	0.081
establishment or maintenance of apical basal cell polarity	GO:0035088	34	0.081
non sensory hair organization	GO:0035316	47	0.081
cellular response to dna damage stimulus	GO:0006974	223	0.080
regulation of cellular amino acid metabolic process	GO:0006521	0	0.080
regulation of ras gtpase activity	GO:0032318	38	0.080
positive regulation of cell development	GO:0010720	61	0.079
gastrulation	GO:0007369	70	0.078
regulation of nucleotide catabolic process	GO:0030811	48	0.078
regulation of epithelial cell migration open tracheal system	GO:2000274	11	0.077
positive regulation of peptidyl tyrosine phosphorylation	GO:0050731	4	0.077
cellular response to chemical stimulus	GO:0070887	199	0.077
male mating behavior	GO:0060179	70	0.076
regulation of anatomical structure size	GO:0090066	163	0.075
membrane invagination	GO:0010324	11	0.075
cellular amino acid metabolic process	GO:0006520	61	0.075
imaginal disc derived wing vein morphogenesis	GO:0008586	44	0.074
imaginal disc derived wing vein specification	GO:0007474	48	0.074
membrane organization	GO:0061024	112	0.074
regulation of actin polymerization or depolymerization	GO:0008064	27	0.074
signal transduction by phosphorylation	GO:0023014	107	0.073
purine nucleotide catabolic process	GO:0006195	109	0.073
positive regulation of cell projection organization	GO:0031346	29	0.073
gtp catabolic process	GO:0006184	72	0.072
regulation of actin filament length	GO:0030832	27	0.072
respiratory system development	GO:0060541	213	0.071
stem cell development	GO:0048864	79	0.071
pericardium morphogenesis	GO:0003344	2	0.071
oxoacid metabolic process	GO:0043436	103	0.071
regulation of cell morphogenesis involved in differentiation	GO:0010769	61	0.070
mitotic spindle organization	GO:0007052	220	0.070
positive regulation of catalytic activity	GO:0043085	118	0.069
myotube differentiation	GO:0014902	46	0.069
nucleoside phosphate metabolic process	GO:0006753	162	0.069
positive regulation of phosphate metabolic process	GO:0045937	139	0.069
positive regulation of cellular biosynthetic process	GO:0031328	316	0.068
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.068
negative regulation of rna biosynthetic process	GO:1902679	240	0.068
oocyte microtubule cytoskeleton organization	GO:0016325	35	0.068
positive regulation of gene expression	GO:0010628	290	0.068
purine ribonucleoside catabolic process	GO:0046130	112	0.067
divalent metal ion transport	GO:0070838	26	0.066
purine ribonucleoside metabolic process	GO:0046128	127	0.066
glycosyl compound catabolic process	GO:1901658	112	0.066
dendrite self avoidance	GO:0070593	8	0.066
cellular ion homeostasis	GO:0006873	39	0.066
oxidation reduction process	GO:0055114	123	0.066
negative regulation of signal transduction	GO:0009968	206	0.065
rho protein signal transduction	GO:0007266	14	0.065
regulation of secretion by cell	GO:1903530	39	0.064
positive regulation of notch signaling pathway	GO:0045747	34	0.064
organic cyclic compound catabolic process	GO:1901361	168	0.064
ovarian follicle cell stalk formation	GO:0030713	17	0.064
positive regulation of cellular component biogenesis	GO:0044089	80	0.063
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	116	0.063
ion homeostasis	GO:0050801	55	0.062
regulation of cell motility	GO:2000145	23	0.062
cellular catabolic process	GO:0044248	372	0.061
formation of primary germ layer	GO:0001704	24	0.061
planar cell polarity pathway involved in axis elongation	GO:0003402	3	0.060
regulation of lamellipodium assembly	GO:0010591	15	0.060
neuromuscular junction development	GO:0007528	149	0.060
hindgut development	GO:0061525	58	0.059
neuroblast differentiation	GO:0014016	29	0.059
asymmetric neuroblast division	GO:0055059	33	0.058
apoptotic process	GO:0006915	159	0.058
renal tubule development	GO:0061326	64	0.058
sex determination	GO:0007530	18	0.057
regulation of gtp catabolic process	GO:0033124	44	0.057
digestive tract development	GO:0048565	149	0.057
retinal ganglion cell axon guidance	GO:0031290	12	0.055
cell competition in a multicellular organism	GO:0035212	10	0.055
positive regulation of protein metabolic process	GO:0051247	128	0.055
regulation of endocytosis	GO:0030100	37	0.054
purine ribonucleoside triphosphate metabolic process	GO:0009205	119	0.054
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.054
organophosphate catabolic process	GO:0046434	112	0.054
dormancy process	GO:0022611	2	0.054
phagocytosis	GO:0006909	215	0.054
embryonic heart tube development	GO:0035050	22	0.053
actin polymerization or depolymerization	GO:0008154	31	0.053
germ cell migration	GO:0008354	43	0.053
regulation of behavior	GO:0050795	75	0.053
positive regulation of signaling	GO:0023056	243	0.053
defense response	GO:0006952	300	0.052
regulation of cellular localization	GO:0060341	136	0.052
negative regulation of rna metabolic process	GO:0051253	251	0.052
organ formation	GO:0048645	39	0.051
regulation of epithelial cell proliferation	GO:0050678	4	0.051
purine nucleoside triphosphate catabolic process	GO:0009146	108	0.051
positive regulation of nucleotide catabolic process	GO:0030813	46	0.051
segmentation	GO:0035282	207	0.050
imaginal disc pattern formation	GO:0007447	91	0.050
regulation of hematopoietic progenitor cell differentiation	GO:1901532	1	0.050
amine metabolic process	GO:0009308	12	0.050
regulation of cellular amine metabolic process	GO:0033238	3	0.049
stem cell division	GO:0017145	69	0.048
synapse organization	GO:0050808	196	0.048
regulation of protein modification process	GO:0031399	112	0.048
chromatin organization	GO:0006325	207	0.048
protein transport	GO:0015031	155	0.047
protein complex assembly	GO:0006461	200	0.047
eye photoreceptor cell development	GO:0042462	81	0.047
establishment or maintenance of monopolar cell polarity	GO:0061339	15	0.047
purine containing compound catabolic process	GO:0072523	112	0.047
carbohydrate derivative catabolic process	GO:1901136	118	0.047
hemocyte migration	GO:0035099	19	0.046
exocrine system development	GO:0035272	162	0.046
camera type eye morphogenesis	GO:0048593	2	0.046
metal ion homeostasis	GO:0055065	44	0.046
establishment of localization in cell	GO:0051649	402	0.046
neurological system process	GO:0050877	358	0.045
regulation of axon extension	GO:0030516	8	0.045
ensheathment of neurons	GO:0007272	10	0.045
regulation of actin cytoskeleton organization	GO:0032956	42	0.044
peptidyl tyrosine modification	GO:0018212	24	0.044
regulation of cellular protein metabolic process	GO:0032268	243	0.044
nephron morphogenesis	GO:0072028	3	0.044
nerve development	GO:0021675	6	0.044
regulation of cell proliferation	GO:0042127	163	0.044
vesicle organization	GO:0016050	44	0.043
negative regulation of epithelial cell migration	GO:0010633	1	0.043
glycosyl compound metabolic process	GO:1901657	127	0.043
negative regulation of hippo signaling	GO:0035331	5	0.043
ribonucleoside metabolic process	GO:0009119	127	0.042
positive regulation of cellular amine metabolic process	GO:0033240	0	0.042
chemical homeostasis	GO:0048878	92	0.042
guanosine containing compound catabolic process	GO:1901069	74	0.042
positive regulation of neurogenesis	GO:0050769	41	0.042
regulation of dna templated transcription elongation	GO:0032784	17	0.042
regulation of locomotion	GO:0040012	42	0.042
phosphorylation	GO:0016310	294	0.042
regulation of epithelial cell migration	GO:0010632	12	0.042
notch receptor processing	GO:0007220	13	0.041
embryonic epithelial tube formation	GO:0001838	6	0.041
carboxylic acid metabolic process	GO:0019752	92	0.041
regulation of glial cell differentiation	GO:0045685	1	0.040
regulation of hemocyte differentiation	GO:0045610	22	0.040
regulation of cyclin dependent protein serine threonine kinase activity	GO:0000079	3	0.040
protein phosphorylation	GO:0006468	169	0.040
positive regulation of purine nucleotide metabolic process	GO:1900544	55	0.040
regulation of epidermal growth factor receptor signaling pathway	GO:0042058	42	0.040
oocyte microtubule cytoskeleton polarization	GO:0008103	22	0.040
cellular response to abiotic stimulus	GO:0071214	58	0.039
regulation of protein metabolic process	GO:0051246	256	0.039
photoreceptor cell fate commitment	GO:0046552	41	0.039
cellular homeostasis	GO:0019725	80	0.039
organ growth	GO:0035265	56	0.039
epithelial cell morphogenesis	GO:0003382	25	0.039
response to biotic stimulus	GO:0009607	294	0.039
eye photoreceptor cell fate commitment	GO:0042706	37	0.039
morphogenesis of a branching epithelium	GO:0061138	45	0.039
positive regulation of protein modification process	GO:0031401	58	0.037
detection of stimulus	GO:0051606	156	0.037
positive regulation of cellular amino acid metabolic process	GO:0045764	0	0.037
protein localization	GO:0008104	284	0.037
regulation of purine nucleotide catabolic process	GO:0033121	48	0.037
peripheral nervous system neuron differentiation	GO:0048934	8	0.037
endomembrane system organization	GO:0010256	119	0.036
nephron epithelium development	GO:0072009	3	0.036
neuroblast fate commitment	GO:0014017	19	0.036
neuron remodeling	GO:0016322	29	0.036
muscle fiber development	GO:0048747	12	0.036
positive regulation of cellular component organization	GO:0051130	156	0.036
nucleoside triphosphate metabolic process	GO:0009141	120	0.035
intracellular transport	GO:0046907	228	0.035
imaginal disc derived wing hair outgrowth	GO:0035318	1	0.035
peptidyl tyrosine phosphorylation	GO:0018108	24	0.035
anatomical structure homeostasis	GO:0060249	97	0.035
positive regulation of nucleotide metabolic process	GO:0045981	55	0.034
cation homeostasis	GO:0055080	51	0.034
substrate dependent cell migration	GO:0006929	3	0.034
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.034
apical constriction	GO:0003383	18	0.034
negative regulation of neurogenesis	GO:0050768	53	0.034
organonitrogen compound catabolic process	GO:1901565	128	0.034
asymmetric cell division	GO:0008356	37	0.034
regulation of mapk cascade	GO:0043408	92	0.034
regulation of small gtpase mediated signal transduction	GO:0051056	93	0.034
regulation of eye photoreceptor cell development	GO:0042478	13	0.034
negative regulation of signaling	GO:0023057	219	0.034
neuromuscular process	GO:0050905	21	0.033
regulation of stem cell differentiation	GO:2000736	14	0.033
anterior commissure morphogenesis	GO:0021960	2	0.033
cell type specific apoptotic process	GO:0097285	38	0.033
organic acid metabolic process	GO:0006082	103	0.033
aggressive behavior	GO:0002118	63	0.032
purine nucleoside catabolic process	GO:0006152	112	0.032
regulation of cell migration	GO:0030334	22	0.032
autophagic vacuole assembly	GO:0000045	2	0.031
regulation of synaptic growth at neuromuscular junction	GO:0008582	89	0.031
r1 r6 cell differentiation	GO:0048052	4	0.031
male courtship behavior	GO:0008049	63	0.031
cellular lipid metabolic process	GO:0044255	83	0.031
nucleoside catabolic process	GO:0009164	112	0.031
generation of precursor metabolites and energy	GO:0006091	42	0.030
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.030
positive regulation of photoreceptor cell differentiation	GO:0046534	12	0.030
immune system development	GO:0002520	57	0.030
establishment of planar polarity	GO:0001736	87	0.030
neuronal stem cell division	GO:0036445	35	0.029
positive regulation of stem cell proliferation	GO:2000648	8	0.029
actomyosin structure organization	GO:0031032	56	0.029
anterior posterior pattern specification	GO:0009952	136	0.029
ommatidial rotation	GO:0016318	20	0.029

kuz disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	disease of anatomical entity	DOID:7	0	0.320

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