Drosophila melanogaster

15 known processes

Idh (Dmel_CG7176)

Isocitrate dehydrogenase

(Aliases: l(3)L3852,Idh-NADP,Dmel\CG7176,idh,IDH,CT22171,CG7176,isocitrate dehydrogenase,IDH-NADP)

Idh biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
organic acid metabolic processGO:00060821030.968
small molecule metabolic processGO:00442813050.829
carboxylic acid metabolic processGO:0019752920.822
nicotinamide nucleotide metabolic processGO:004649620.589
oxoacid metabolic processGO:00434361030.546
monocarboxylic acid metabolic processGO:0032787290.541
Yeast
cellular amino acid metabolic processGO:0006520610.486
Yeast Mouse
organonitrogen compound metabolic processGO:19015643180.404
Yeast Mouse
agingGO:00075681430.386
fatty acid beta oxidationGO:000663560.320
Yeast
glutamate metabolic processGO:000653650.290
Yeast
lipid catabolic processGO:0016042210.260
Yeast
pyridine nucleotide metabolic processGO:001936220.256
catabolic processGO:00090564090.250
Yeast
pyridine containing compound metabolic processGO:007252430.233
cellular ketone metabolic processGO:0042180240.225
oxidation reduction processGO:00551141230.222
small molecule catabolic processGO:0044282210.210
Yeast
lateral inhibitionGO:00463312060.201
organic substance catabolic processGO:19015753080.182
Yeast
negative regulation of biosynthetic processGO:00098902770.170
thioester metabolic processGO:003538330.162
organophosphate metabolic processGO:00196371950.151
carboxylic acid catabolic processGO:0046395160.143
Yeast
response to organic substanceGO:00100332840.134
Rat
cellular response to chemical stimulusGO:00708871990.130
homeostatic processGO:00425921990.120
single organism catabolic processGO:00447122280.118
Yeast
cellular ion homeostasisGO:0006873390.118
lipid metabolic processGO:00066291210.111
Yeast
cellular catabolic processGO:00442483720.109
Yeast
regulation of cellular ketone metabolic processGO:001056530.103
cellular lipid metabolic processGO:0044255830.103
Yeast
establishment of localization in cellGO:00516494020.095
acyl coa metabolic processGO:000663730.094
oxidoreduction coenzyme metabolic processGO:000673320.088
sulfur compound metabolic processGO:0006790590.085
Mouse
single organism biosynthetic processGO:00447112060.078
Yeast
spermatogenesisGO:00072832000.077
multicellular organismal agingGO:00102591400.071
cell cell signaling involved in cell fate commitmentGO:00451682100.070
organic acid transportGO:0015849180.066
response to oxygen containing compoundGO:19017002000.062
single organism carbohydrate metabolic processGO:0044723720.056
regulation of apoptotic processGO:00429811300.054
epithelial cell differentiationGO:00308553220.054
organic substance transportGO:00717022570.048
endocytosisGO:00068973100.047
nad metabolic processGO:001967410.046
ion transportGO:00068111450.046
negative regulation of cellular biosynthetic processGO:00313272770.045
positive regulation of cell communicationGO:00106472500.045
transition metal ion homeostasisGO:0055076170.044
head developmentGO:00603221350.043
nucleobase containing small molecule metabolic processGO:00550861740.041
protein complex biogenesisGO:00702712010.037
neurological system processGO:00508773580.037
negative regulation of cellular metabolic processGO:00313243820.037
regulation of localizationGO:00328792750.036
cellular cation homeostasisGO:0030003380.035
negative regulation of nucleobase containing compound metabolic processGO:00459342610.035
hormone metabolic processGO:0042445330.033
negative regulation of gene expressionGO:00106293870.033
response to hypoxiaGO:0001666530.032
vesicle mediated transportGO:00161923810.032
programmed cell deathGO:00125012570.031
organic anion transportGO:0015711280.030
synapse organizationGO:00508081960.030
organonitrogen compound catabolic processGO:19015651280.030
negative regulation of nitrogen compound metabolic processGO:00511722650.030
carbohydrate metabolic processGO:0005975820.029
single organism intracellular transportGO:19025822070.029
energy derivation by oxidation of organic compoundsGO:0015980320.029
positive regulation of cell deathGO:0010942690.028
body morphogenesisGO:001017120.027
cellular amine metabolic processGO:0044106120.027
chemical homeostasisGO:0048878920.027
response to abiotic stimulusGO:00096283410.027
positive regulation of signalingGO:00230562430.026
maintenance of locationGO:0051235730.026
regulation of cellular amine metabolic processGO:003323830.026
response to endogenous stimulusGO:00097191190.026
Rat
pyruvate metabolic processGO:000609070.025
intracellular transportGO:00469072280.025
gland developmentGO:00487321910.024
nucleotide metabolic processGO:00091171610.024
response to nutrient levelsGO:00316671140.023
ion homeostasisGO:0050801550.023
embryonic morphogenesisGO:00485982060.023
forebrain developmentGO:003090020.023
positive regulation of multicellular organismal processGO:00512401430.023
synapse assemblyGO:00074161430.023
central nervous system developmentGO:00074172010.023
centrosome duplicationGO:00512981210.023
regulation of programmed cell deathGO:00430671520.022
carbohydrate derivative metabolic processGO:19011352170.022
cell deathGO:00082192790.022
regulation of cellular localizationGO:00603411360.021
heart developmentGO:0007507820.021
cellular hormone metabolic processGO:0034754230.021
metal ion homeostasisGO:0055065440.021
apoptotic processGO:00069151590.021
transcription from rna polymerase ii promoterGO:00063663680.021
response to extracellular stimulusGO:00099911160.020
cellular amino acid biosynthetic processGO:000865290.020
Yeast
amine catabolic processGO:000931010.020
anion transportGO:0006820410.020
glycerolipid metabolic processGO:0046486340.020
deathGO:00162652840.020
mitotic spindle organizationGO:00070522200.020
glucan biosynthetic processGO:000925020.020
imaginal disc derived wing morphogenesisGO:00074763370.019
pentose metabolic processGO:001932110.019
membrane organizationGO:00610241120.019
organonitrogen compound biosynthetic processGO:19015661170.019
Yeast
regulation of cell deathGO:00109411730.019
cation homeostasisGO:0055080510.019
response to metal ionGO:0010038230.019
positive regulation of transportGO:0051050920.018
regulation of growthGO:00400082330.018
nitrogen compound transportGO:0071705850.018
sex differentiationGO:0007548810.018
Rat
nucleoside phosphate metabolic processGO:00067531620.018
response to hexoseGO:000974630.018
small molecule biosynthetic processGO:0044283370.018
Yeast
glucose metabolic processGO:000600650.018
striated muscle myosin thick filament assemblyGO:007168830.017
glutamine family amino acid metabolic processGO:0009064120.017
Yeast
tube developmentGO:00352952440.017
organic hydroxy compound metabolic processGO:1901615830.017
tricarboxylic acid metabolic processGO:007235010.017
cell agingGO:000756920.017
cellular homeostasisGO:0019725800.017
regulation of cellular protein metabolic processGO:00322682430.017
appendage morphogenesisGO:00351073970.017
protein complex assemblyGO:00064612000.016
intracellular signal transductionGO:00355563000.016
cellular response to organic substanceGO:00713101320.016
proteolysisGO:00065081920.016
cellular metal ion homeostasisGO:0006875310.016
visual learningGO:000854240.016
lipid localizationGO:0010876540.015
carbohydrate derivative biosynthetic processGO:1901137850.015
determination of adult lifespanGO:00083401370.015
carboxylic acid biosynthetic processGO:0046394150.015
Yeast
cellular response to hormone stimulusGO:0032870440.015
protein modification processGO:00362114380.014
regulation of cellular amino acid metabolic processGO:000652100.014
positive regulation of response to stimulusGO:00485843230.014
macromolecular complex assemblyGO:00650032560.014
cellular macromolecular complex assemblyGO:00346221530.014
organophosphate biosynthetic processGO:0090407460.014
kidney developmentGO:000182230.014
ph reductionGO:004585170.014
epithelial cell developmentGO:00020642740.014
embryo development ending in birth or egg hatchingGO:00097921520.014
aromatic amino acid family metabolic processGO:000907230.014
imaginal disc derived appendage developmentGO:00487373990.013
regulation of rac protein signal transductionGO:003502030.013
water homeostasisGO:003010430.013
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.013
cell maturationGO:00484691440.013
wing disc morphogenesisGO:00074723440.013
heterocycle catabolic processGO:00467001660.013
single organism carbohydrate catabolic processGO:004472470.013
cell proliferationGO:00082832990.013
regulation of intracellular signal transductionGO:19025312360.013
positive regulation of reactive oxygen species metabolic processGO:200037900.013
neutral lipid biosynthetic processGO:004646020.013
response to oxygen levelsGO:0070482590.013
regulation of cell proliferationGO:00421271630.013
cardiovascular system developmentGO:0072358820.013
cellular component assembly involved in morphogenesisGO:00109271510.013
response to monosaccharideGO:003428440.012
cellular aldehyde metabolic processGO:0006081100.012
male gamete generationGO:00482322010.012
spindle organizationGO:00070512530.012
cellular polysaccharide metabolic processGO:0044264110.012
appendage developmentGO:00487364010.012
histolysisGO:00075591020.012
acyl coa biosynthetic processGO:007161620.012
telencephalon developmentGO:002153720.012
response to decreased oxygen levelsGO:0036293580.012
generation of precursor metabolites and energyGO:0006091420.012
organic cyclic compound catabolic processGO:19013611680.012
brain developmentGO:00074201200.011
amine metabolic processGO:0009308120.011
regulation of catalytic activityGO:00507901850.011
negative regulation of cell differentiationGO:00455961430.011
alcohol metabolic processGO:0006066250.011
taxisGO:00423303040.011
negative regulation of rna metabolic processGO:00512532510.011
regulation of proteolysisGO:0030162870.011
development of primary sexual characteristicsGO:0045137500.011
Rat
exocrine system developmentGO:00352721620.011
open tracheal system developmentGO:00074242040.011
positive regulation of programmed cell deathGO:0043068620.011
positive regulation of signal transductionGO:00099672230.011
regulation of cell cycleGO:00517262910.011
purine nucleotide metabolic processGO:00061631460.011
glutamine family amino acid catabolic processGO:000906530.011
connective tissue developmentGO:006144830.011
renal system developmentGO:0072001720.010
organic acid biosynthetic processGO:0016053150.010
Yeast
circulatory system developmentGO:0072359820.010
carbohydrate biosynthetic processGO:0016051170.010
negative regulation of homeostatic processGO:003284520.010
developmental growthGO:00485892800.010
alpha amino acid metabolic processGO:1901605200.010
Yeast

Idh disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
inherited metabolic disorderDOID:65500.298
disease of metabolismDOID:001466700.298
carbohydrate metabolism diseaseDOID:005001300.046
glucose metabolism diseaseDOID:419400.046
acquired metabolic diseaseDOID:006015800.046
disease of anatomical entityDOID:700.019
cancerDOID:16200.013
disease of cellular proliferationDOID:1456600.013
nervous system diseaseDOID:86300.012