Drosophila melanogaster

214 known processes

Tab2 (Dmel_CG7417)

TAK1-associated binding protein 2

(Aliases: ORF1,Dmel\CG7417,TAB2,galere,7417,TAB,cg7417,CG7417,dTAB2)

Tab2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
lateral inhibitionGO:00463312060.878
immune system processGO:00023763470.865
immune effector processGO:0002252980.860
establishment of localization in cellGO:00516494020.842
positive regulation of nitrogen compound metabolic processGO:00511733540.666
mitotic spindle organizationGO:00070522200.657
intracellular transportGO:00469072280.588
negative regulation of cell communicationGO:00106482230.583
regulation of protein metabolic processGO:00512462560.571
dendrite morphogenesisGO:00488131990.547
protein localizationGO:00081042840.514
positive regulation of gene expressionGO:00106282900.477
positive regulation of macromolecule metabolic processGO:00106044050.465
single organism intracellular transportGO:19025822070.405
cell cell signaling involved in cell fate commitmentGO:00451682100.386
organic substance transportGO:00717022570.384
negative regulation of response to stimulusGO:00485852580.383
regulation of response to stressGO:00801342000.376
negative regulation of signal transductionGO:00099682060.373
cell adhesionGO:00071551360.356
negative regulation of signalingGO:00230572190.351
endosomal transportGO:0016197440.347
regulation of transportGO:00510491810.346
positive regulation of molecular functionGO:00440931360.340
cellular macromolecular complex assemblyGO:00346221530.338
regulation of immune system processGO:00026821760.332
macromolecular complex assemblyGO:00650032560.330
cellular catabolic processGO:00442483720.322
protein complex assemblyGO:00064612000.318
positive regulation of cellular biosynthetic processGO:00313283160.296
catabolic processGO:00090564090.294
intracellular signal transductionGO:00355563000.279
protein phosphorylationGO:00064681690.269
protein complex biogenesisGO:00702712010.260
organic substance catabolic processGO:19015753080.260
macromolecule catabolic processGO:00090571610.244
regulation of organelle organizationGO:00330431960.238
intracellular protein transportGO:00068861040.238
asymmetric cell divisionGO:0008356370.234
vesicle mediated transportGO:00161923810.230
dendrite developmentGO:00163582040.226
regulation of cellular protein metabolic processGO:00322682430.215
positive regulation of immune effector processGO:0002699280.205
positive regulation of response to stimulusGO:00485843230.203
regulation of cell differentiationGO:00455953020.199
actin filament organizationGO:00070151260.194
regulation of immune effector processGO:0002697520.193
positive regulation of defense responseGO:0031349590.189
regulation of localizationGO:00328792750.188
organonitrogen compound metabolic processGO:19015643180.186
regulation of response to external stimulusGO:00321011150.186
central nervous system developmentGO:00074172010.185
positive regulation of cell projection organizationGO:0031346290.185
spindle organizationGO:00070512530.180
regulation of cellular amide metabolic processGO:0034248390.177
positive regulation of transcription dna templatedGO:00458932660.177
protein transportGO:00150311550.177
proteasomal protein catabolic processGO:0010498590.162
jnk cascadeGO:0007254500.159
regulation of cell projection organizationGO:0031344920.158
regulation of multicellular organismal developmentGO:20000264140.157
tissue morphogenesisGO:00487292970.151
response to organic substanceGO:00100332840.150
positive regulation of cell differentiationGO:0045597640.149
regulation of molecular functionGO:00650092170.148
regulation of cytoskeleton organizationGO:0051493890.147
regulation of cell deathGO:00109411730.145
positive regulation of macromolecule biosynthetic processGO:00105572830.139
synapse assemblyGO:00074161430.137
positive regulation of nucleobase containing compound metabolic processGO:00459353320.134
regulation of cellular component biogenesisGO:00440872010.132
proteolysis involved in cellular protein catabolic processGO:0051603830.131
regulation of antimicrobial peptide productionGO:0002784440.130
regulation of secretionGO:0051046440.127
embryonic morphogenesisGO:00485982060.124
regulation of nervous system developmentGO:00519602480.121
regulation of response to biotic stimulusGO:0002831630.120
endocytosisGO:00068973100.119
secretionGO:00469031090.119
secretion by cellGO:00329401010.118
single organism behaviorGO:00447083910.117
cellular response to chemical stimulusGO:00708871990.116
positive regulation of signal transductionGO:00099672230.115
response to oxygen containing compoundGO:19017002000.112
regulation of cellular ketone metabolic processGO:001056530.110
synapse organizationGO:00508081960.107
establishment of protein localizationGO:00451841630.106
cytoplasmic transportGO:00164821300.103
biological adhesionGO:00226101380.102
regulation of cellular response to stressGO:0080135890.102
cellular ketone metabolic processGO:0042180240.101
positive regulation of programmed cell deathGO:0043068620.100
negative regulation of cell proliferationGO:0008285690.100
golgi vesicle transportGO:0048193270.099
single organism cellular localizationGO:19025801800.098
regulation of synapse structure and activityGO:00508031280.098
positive regulation of catalytic activityGO:00430851180.097
regulation of immune responseGO:00507761180.097
positive regulation of signalingGO:00230562430.095
cellular macromolecule catabolic processGO:00442651360.095
positive regulation of biosynthetic processGO:00098913160.094
positive regulation of cell communicationGO:00106472500.093
positive regulation of immune system processGO:0002684680.091
deathGO:00162652840.089
hematopoietic or lymphoid organ developmentGO:0048534570.089
antimicrobial humoral responseGO:0019730990.087
circulatory system developmentGO:0072359820.087
cellular macromolecule localizationGO:00707272200.085
peptidyl amino acid modificationGO:00181931050.083
negative regulation of notch signaling pathwayGO:0045746410.083
positive regulation of cellular protein metabolic processGO:00322701180.082
protein modification processGO:00362114380.082
negative regulation of intracellular signal transductionGO:1902532570.082
mitochondrion organizationGO:0007005650.081
regulation of multi organism processGO:00439001310.081
response to other organismGO:00517072930.080
regulation of defense responseGO:00313471020.079
regulation of cellular localizationGO:00603411360.079
positive regulation of apoptotic processGO:0043065470.078
positive regulation of developmental processGO:00510941430.075
organonitrogen compound biosynthetic processGO:19015661170.075
purine ribonucleoside metabolic processGO:00461281270.074
positive regulation of cell deathGO:0010942690.072
cellular nitrogen compound catabolic processGO:00442701650.072
regulation of production of molecular mediator of immune responseGO:0002700440.070
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178650.070
cell divisionGO:00513012480.069
positive regulation of transportGO:0051050920.069
response to external biotic stimulusGO:00432072930.069
actin filament based processGO:00300292200.067
positive regulation of cell developmentGO:0010720610.067
regulation of humoral immune responseGO:0002920510.066
positive regulation of nervous system developmentGO:0051962690.065
cell fate determinationGO:0001709910.065
embryo development ending in birth or egg hatchingGO:00097921520.065
regulation of apoptotic processGO:00429811300.064
positive regulation of multicellular organismal processGO:00512401430.062
response to abiotic stimulusGO:00096283410.062
regulation of growthGO:00400082330.061
male courtship behavior veined wing generated song productionGO:0045433200.060
amide biosynthetic processGO:0043604420.058
small molecule metabolic processGO:00442813050.058
antimicrobial peptide productionGO:0002775460.056
regulation of cell cycleGO:00517262910.056
carbohydrate derivative catabolic processGO:19011361180.056
immune system developmentGO:0002520570.056
apoptotic processGO:00069151590.055
nucleotide metabolic processGO:00091171610.055
purine containing compound catabolic processGO:00725231120.054
cellular protein catabolic processGO:0044257830.054
regulation of cellular catabolic processGO:00313291570.054
regulation of cellular amine metabolic processGO:003323830.054
response to nutrient levelsGO:00316671140.053
cellular protein modification processGO:00064644380.053
regulation of antimicrobial humoral responseGO:0002759500.051
regulation of nucleotide catabolic processGO:0030811480.050
single organism catabolic processGO:00447122280.050
protein secretionGO:0009306450.049
regulation of neurogenesisGO:00507671580.049
negative regulation of sequence specific dna binding transcription factor activityGO:004343340.049
negative regulation of cellular protein metabolic processGO:0032269850.049
regulation of programmed cell deathGO:00430671520.049
carboxylic acid metabolic processGO:0019752920.049
purine nucleotide catabolic processGO:00061951090.049
proteolysisGO:00065081920.048
modification dependent macromolecule catabolic processGO:0043632790.048
modification dependent protein catabolic processGO:0019941780.047
developmental maturationGO:00217001720.047
single organism nuclear importGO:1902593510.047
response to biotic stimulusGO:00096072940.047
protein catabolic processGO:00301631010.046
endomembrane system organizationGO:00102561190.046
defense responseGO:00069523000.046
organophosphate metabolic processGO:00196371950.045
regulation of catalytic activityGO:00507901850.045
locomotory behaviorGO:00076261760.045
regulation of cell proliferationGO:00421271630.044
purine nucleotide metabolic processGO:00061631460.043
regulation of defense response to virus by hostGO:0050691100.043
positive regulation of antimicrobial peptide productionGO:0002225280.042
negative regulation of nitrogen compound metabolic processGO:00511722650.042
regulation of antimicrobial peptide biosynthetic processGO:0002805380.041
columnar cuboidal epithelial cell differentiationGO:00020652560.041
regulation of vesicle mediated transportGO:0060627590.041
immune responseGO:00069552460.041
regulation of cell cycle processGO:00105641810.041
nucleobase containing small molecule metabolic processGO:00550861740.040
anatomical structure homeostasisGO:0060249970.040
purine nucleoside metabolic processGO:00422781270.040
cellular protein complex assemblyGO:0043623710.040
melanization defense responseGO:0035006450.039
positive regulation of catabolic processGO:00098961050.039
guanosine containing compound metabolic processGO:1901068740.038
morphogenesis of an epitheliumGO:00020092760.038
cellular response to organic substanceGO:00713101320.038
golgi organizationGO:0007030660.038
positive regulation of rna metabolic processGO:00512542710.038
positive regulation of nucleic acid templated transcriptionGO:19035082660.038
cellular component disassemblyGO:0022411460.038
positive regulation of response to external stimulusGO:0032103440.037
phagocytosisGO:00069092150.037
regulation of anatomical structure morphogenesisGO:00226032420.037
small gtpase mediated signal transductionGO:0007264880.036
cellular amino acid metabolic processGO:0006520610.036
ovarian follicle cell developmentGO:00307072480.036
defense response to other organismGO:00985422250.035
cell deathGO:00082192790.035
regulation of phosphorus metabolic processGO:00511742100.035
chaeta developmentGO:0022416970.035
ribonucleotide metabolic processGO:00092591450.035
extracellular structure organizationGO:0043062460.034
positive regulation of secretionGO:0051047220.034
phosphorylationGO:00163102940.034
translationGO:0006412690.033
purine containing compound metabolic processGO:00725211550.033
regulation of intracellular signal transductionGO:19025312360.033
regulation of cell shapeGO:00083601130.033
stress activated mapk cascadeGO:0051403520.032
nucleocytoplasmic transportGO:0006913720.032
production of molecular mediator of immune responseGO:0002440460.032
single organism membrane organizationGO:0044802930.032
organelle fissionGO:00482853400.032
positive regulation of immune responseGO:0050778630.032
negative regulation of mitotic cell cycleGO:00459301090.032
nucleobase containing compound catabolic processGO:00346551650.031
stress activated protein kinase signaling cascadeGO:0031098550.031
dephosphorylationGO:0016311510.031
positive regulation of response to biotic stimulusGO:0002833310.030
homeostatic processGO:00425921990.030
forebrain developmentGO:003090020.030
programmed cell deathGO:00125012570.030
positive regulation of rna biosynthetic processGO:19026802660.030
ribose phosphate metabolic processGO:00196931450.030
endocytic recyclingGO:0032456130.030
peptide biosynthetic processGO:0043043420.030
protein localization to organelleGO:0033365820.029
response to toxic substanceGO:0009636220.029
tube developmentGO:00352952440.028
enzyme linked receptor protein signaling pathwayGO:00071671790.028
regulation of mitotic cell cycleGO:00073461900.028
negative regulation of multicellular organismal processGO:00512411420.028
positive regulation of cellular catabolic processGO:0031331950.027
receptor mediated endocytosisGO:0006898210.027
regulation of stress activated protein kinase signaling cascadeGO:0070302420.027
appendage developmentGO:00487364010.027
epithelial cell migrationGO:00106311480.027
response to endogenous stimulusGO:00097191190.026
regulation of developmental growthGO:00486381740.026
positive regulation of phosphorus metabolic processGO:00105621390.026
response to bacteriumGO:00096171980.026
actin cytoskeleton organizationGO:00300362060.026
appendage morphogenesisGO:00351073970.026
cellular protein localizationGO:00346131600.026
monocarboxylic acid biosynthetic processGO:007233070.026
posttranscriptional regulation of gene expressionGO:00106081450.026
nucleoside phosphate catabolic processGO:19012921100.025
regulation of proteolysisGO:0030162870.025
regulation of dendrite morphogenesisGO:0048814280.025
negative regulation of cell differentiationGO:00455961430.025
mesenchymal cell differentiationGO:004876210.025
cellular component assembly involved in morphogenesisGO:00109271510.025
heterocycle catabolic processGO:00467001660.025
positive regulation of humoral immune responseGO:0002922280.025
organophosphate catabolic processGO:00464341120.024
regulation of secretion by cellGO:1903530390.024
negative regulation of apoptotic processGO:0043066630.024
phototransductionGO:0007602520.024
cell activationGO:000177590.024
regulation of catabolic processGO:00098941700.024
regulation of phosphate metabolic processGO:00192202100.024
regulation of synapse organizationGO:00508071100.024
nuclear importGO:0051170510.024
microtubule based movementGO:0007018510.023
positive regulation of hydrolase activityGO:0051345780.023
negative regulation of rna metabolic processGO:00512532510.023
regulation of neuron projection developmentGO:0010975690.023
regulation of protein localizationGO:0032880760.023
oxoacid metabolic processGO:00434361030.022
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.022
gland morphogenesisGO:00226121450.022
negative regulation of cellular component organizationGO:00511291080.022
negative regulation of protein metabolic processGO:0051248850.022
male courtship behavior veined wing vibrationGO:0016545210.021
jak stat cascadeGO:0007259490.021
regulation of defense response to bacteriumGO:1900424300.021
hemopoiesisGO:0030097460.021
nuclear divisionGO:00002803320.020
response to extracellular stimulusGO:00099911160.020
muscle structure developmentGO:00610612240.020
defense response to gram negative bacteriumGO:0050829940.020
ubiquitin dependent protein catabolic processGO:0006511780.020
organelle assemblyGO:00709251980.020
organic cyclic compound catabolic processGO:19013611680.020
protein localization to nucleusGO:0034504550.020
response to carbohydrateGO:0009743150.020
response to lipopolysaccharideGO:003249640.019
larval developmentGO:00021641040.019
regulation of purine nucleotide metabolic processGO:1900542620.019
positive regulation of protein metabolic processGO:00512471280.019
carbohydrate derivative metabolic processGO:19011352170.019
nucleoside triphosphate catabolic processGO:00091431080.019
regulation of transferase activityGO:0051338580.019
negative regulation of developmental processGO:00510932010.019
positive regulation of mitochondrion organizationGO:001082280.019
cell proliferationGO:00082832990.019
respiratory system developmentGO:00605412130.018
signal transduction by phosphorylationGO:00230141070.018
nitrogen compound transportGO:0071705850.018
regulation of phosphorylationGO:00423251470.018
positive regulation of protein localization to nucleusGO:1900182210.018
eye morphogenesisGO:00485922600.018
negative regulation of transcription dna templatedGO:00458922370.018
positive regulation of biosynthetic process of antibacterial peptides active against gram negative bacteriaGO:0006964120.018
regulation of hydrolase activityGO:0051336970.018
cardiovascular system developmentGO:0072358820.018
extracellular matrix organizationGO:0030198320.018
response to nitrogen compoundGO:1901698900.018
axonogenesisGO:00074092900.018
negative regulation of cellular metabolic processGO:00313243820.018
regulation of ion transportGO:0043269390.018
nucleoside phosphate metabolic processGO:00067531620.017
dorsal closureGO:0007391790.017
regulation of nucleoside metabolic processGO:0009118500.017
cell migrationGO:00164772380.017
multicellular organismal reproductive behaviorGO:00330571100.017
salivary gland morphogenesisGO:00074351450.017
positive regulation of neurogenesisGO:0050769410.017
regulation of purine nucleotide catabolic processGO:0033121480.016
antibacterial humoral responseGO:0019731440.016
regulation of gtp catabolic processGO:0033124440.016
sex differentiationGO:0007548810.016
positive regulation of developmental growthGO:0048639620.016
response to radiationGO:00093141550.016
response to decreased oxygen levelsGO:0036293580.016
positive regulation of antibacterial peptide biosynthetic processGO:0006963200.016
negative regulation of nucleic acid templated transcriptionGO:19035072400.016
heart developmentGO:0007507820.016
purine nucleoside triphosphate metabolic processGO:00091441190.015
positive regulation of cell motilityGO:200014730.015
nucleoside triphosphate metabolic processGO:00091411200.015
positive regulation of antibacterial peptide productionGO:0002803200.015
ameboidal type cell migrationGO:00016671510.015
establishment of tissue polarityGO:0007164870.015
extrinsic apoptotic signaling pathwayGO:009719110.015
purine nucleoside catabolic processGO:00061521120.015
regulation of antibacterial peptide productionGO:0002786220.015
purine ribonucleotide metabolic processGO:00091501450.015
regulation of cell developmentGO:00602842150.015
positive regulation of intracellular signal transductionGO:19025331160.015
negative regulation of cell deathGO:0060548810.015
gonad developmentGO:0008406500.015
regulation of neuron differentiationGO:00456641030.015
cellular response to growth factor stimulusGO:0071363300.014
mitotic nuclear divisionGO:00070672130.014
gtp metabolic processGO:0046039720.014
response to organonitrogen compoundGO:0010243750.014
embryonic development via the syncytial blastodermGO:00017001480.014
positive regulation of phosphorylationGO:0042327870.014
imaginal disc derived appendage morphogenesisGO:00351143950.014
response to hexoseGO:000974630.014
ion transportGO:00068111450.014
gland developmentGO:00487321910.014
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161540.014
regulation of notch signaling pathwayGO:00085931000.014
centrosome cycleGO:00070981370.013
protein polymerizationGO:0051258420.013
positive regulation of defense response to virus by hostGO:0002230100.013
positive regulation of ion transmembrane transporter activityGO:003241440.013
guanosine containing compound catabolic processGO:1901069740.013
cell type specific apoptotic processGO:0097285380.013
regulation of intracellular protein transportGO:0033157460.013
regulation of cellular amino acid metabolic processGO:000652100.013
morphogenesis of a polarized epitheliumGO:0001738930.013
digestive tract morphogenesisGO:00485461270.013
columnar cuboidal epithelial cell developmentGO:00020662490.013
regulation of anatomical structure sizeGO:00900661630.013
wing disc morphogenesisGO:00074723440.013
response to organic cyclic compoundGO:0014070890.013
negative regulation of molecular functionGO:0044092510.013
reproductive system developmentGO:0061458740.013
taxisGO:00423303040.013
positive regulation of purine nucleotide metabolic processGO:1900544550.013
response to peptide hormoneGO:0043434290.012
regulation of protein localization to nucleusGO:1900180290.012
regulation of actin cytoskeleton organizationGO:0032956420.012
positive regulation of cellular amino acid metabolic processGO:004576400.012
regulation of protein transportGO:0051223570.012
response to hypoxiaGO:0001666530.012
response to hormoneGO:0009725450.012
negative regulation of growthGO:0045926840.012
ribonucleoside triphosphate catabolic processGO:00092031080.012
open tracheal system developmentGO:00074242040.012
positive regulation of phosphate metabolic processGO:00459371390.012
regulation of protein modification processGO:00313991120.012
organic acid metabolic processGO:00060821030.012
morphogenesis of embryonic epitheliumGO:0016331940.012
purine ribonucleoside catabolic processGO:00461301120.012
ribonucleoside triphosphate metabolic processGO:00091991190.012
centrosome duplicationGO:00512981210.012
epithelial cell developmentGO:00020642740.012
cellular response to lipopolysaccharideGO:007122230.011
regulation of mapk cascadeGO:0043408920.011
regulation of stress activated mapk cascadeGO:0032872410.011
positive regulation of nucleocytoplasmic transportGO:0046824240.011
positive regulation of ras gtpase activityGO:0032320360.011
compound eye developmentGO:00487493070.011
wnt signaling pathwayGO:0016055980.011
detection of light stimulusGO:0009583580.011
positive regulation of protein kinase activityGO:0045860250.011
establishment or maintenance of cell polarityGO:00071631670.011
regulation of protein serine threonine kinase activityGO:0071900250.011
cellular response to oxygen containing compoundGO:1901701790.011
cellular response to biotic stimulusGO:007121640.011
salivary gland developmentGO:00074311620.011
response to drugGO:0042493170.011
regulation of cell morphogenesis involved in differentiationGO:0010769610.011
negative regulation of epidermal growth factor receptor signaling pathwayGO:0042059290.011
response to glucoseGO:000974920.011
photoreceptor cell differentiationGO:00465301700.010
nucleotide catabolic processGO:00091661090.010
negative regulation of intrinsic apoptotic signaling pathwayGO:200124310.010
regulation of protein complex assemblyGO:0043254420.010
regulation of small gtpase mediated signal transductionGO:0051056930.010
organonitrogen compound catabolic processGO:19015651280.010
response to starvationGO:0042594970.010
positive regulation of intracellular transportGO:0032388420.010
protein autophosphorylationGO:0046777150.010
negative regulation of immune system processGO:0002683500.010
lipid biosynthetic processGO:0008610460.010
multicellular organismal agingGO:00102591400.010
response to growth factorGO:0070848310.010

Tab2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.041
organ system cancerDOID:005068600.024
disease of cellular proliferationDOID:1456600.024
cancerDOID:16200.024
hair diseaseDOID:42100.018
integumentary system diseaseDOID:1600.018