Drosophila melanogaster

13 known processes

PGRP-SD (Dmel_CG7496)

CG7496 gene product from transcript CG7496-RA

(Aliases: CG7496,Dm PGRP-SD,pgrp-sd,Dmel\CG7496)

PGRP-SD biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
antifungal humoral responseGO:0019732120.994
regulation of biosynthetic process of antibacterial peptides active against gram positive bacteriaGO:000281630.994
Fly
antibacterial humoral responseGO:0019731440.980
Fly
humoral immune responseGO:00069591170.962
Fly
antimicrobial peptide productionGO:0002775460.942
Fly
positive regulation of antimicrobial humoral responseGO:0002760280.935
Fly
positive regulation of biosynthetic process of antibacterial peptides active against gram positive bacteriaGO:000696530.933
Fly
defense response to gram positive bacteriumGO:0050830410.932
immune responseGO:00069552460.928
Fly
regulation of secondary metabolic processGO:004345570.925
Fly
defense response to other organismGO:00985422250.925
positive regulation of biosynthetic process of antibacterial peptides active against gram negative bacteriaGO:0006964120.921
Fly
regulation of biosynthetic process of antibacterial peptides active against gram negative bacteriaGO:0002813140.915
Fly
biosynthetic process of antibacterial peptides active against gram positive bacteriaGO:000281530.912
Fly
defense response to fungusGO:0050832480.910
antimicrobial humoral responseGO:0019730990.901
Fly
negative regulation of peptidoglycan recognition protein signaling pathwayGO:006106030.894
Fly
secondary metabolic processGO:0019748750.890
Fly
response to external biotic stimulusGO:00432072930.889
response to bacteriumGO:00096171980.881
melanization defense responseGO:0035006450.877
Fly
defense response to bacteriumGO:00427421780.869
melanin metabolic processGO:0006582470.866
Fly
regulation of humoral immune responseGO:0002920510.857
Fly
response to biotic stimulusGO:00096072940.856
regulation of defense responseGO:00313471020.850
Fly
defense responseGO:00069523000.847
pattern recognition receptor signaling pathwayGO:000222120.833
Fly
positive regulation of response to biotic stimulusGO:0002833310.828
Fly
immune system processGO:00023763470.826
Fly
antibacterial peptide productionGO:0002778220.820
Fly
response to fungusGO:0009620500.819
regulation of antimicrobial peptide productionGO:0002784440.818
Fly
innate immune responseGO:00450871440.790
Fly
innate immune response activating signal transductionGO:000275820.786
Fly
antibacterial peptide biosynthetic processGO:0002780220.784
Fly
regulation of antimicrobial peptide biosynthetic processGO:0002805380.781
Fly
positive regulation of response to external stimulusGO:0032103440.761
Fly
regulation of antibacterial peptide productionGO:0002786220.760
Fly
cellular amide metabolic processGO:0043603800.754
Fly
immune effector processGO:0002252980.751
Fly
regulation of defense response to bacteriumGO:1900424300.739
Fly
positive regulation of antimicrobial peptide productionGO:0002225280.720
Fly
positive regulation of defense responseGO:0031349590.713
Fly
regulation of antibacterial peptide biosynthetic processGO:0002808220.711
Fly
peptidoglycan recognition protein signaling pathwayGO:0061057160.677
Fly
response to other organismGO:00517072930.670
positive regulation of humoral immune responseGO:0002922280.669
Fly
production of molecular mediator of immune responseGO:0002440460.666
Fly
positive regulation of multi organism processGO:0043902400.661
Fly
peptidoglycan metabolic processGO:000027030.654
Fly
peptidoglycan catabolic processGO:000925330.652
Fly
activation of innate immune responseGO:000221840.644
Fly
glycosaminoglycan catabolic processGO:000602730.643
Fly
positive regulation of antibacterial peptide productionGO:0002803200.637
Fly
defense response to virusGO:0051607230.637
Fly
positive regulation of antimicrobial peptide biosynthetic processGO:0002807260.622
Fly
regulation of antimicrobial humoral responseGO:0002759500.601
Fly
defense response to gram negative bacteriumGO:0050829940.586
Fly
peptide metabolic processGO:0006518800.576
Fly
regulation of multi organism processGO:00439001310.560
Fly
antimicrobial peptide biosynthetic processGO:0002777380.554
Fly
regulation of melanization defense responseGO:003500760.542
Fly
amide biosynthetic processGO:0043604420.536
Fly
regulation of production of molecular mediator of immune responseGO:0002700440.520
Fly
immune response activating signal transductionGO:000275720.492
Fly
biosynthetic process of antibacterial peptides active against gram negative bacteriaGO:0002812140.478
Fly
positive regulation of antibacterial peptide biosynthetic processGO:0006963200.470
Fly
organic hydroxy compound metabolic processGO:1901615830.463
Fly
positive regulation of immune responseGO:0050778630.462
Fly
regulation of immune responseGO:00507761180.462
Fly
regulation of response to biotic stimulusGO:0002831630.436
Fly
positive regulation of defense response to bacteriumGO:1900426230.435
Fly
glycosaminoglycan metabolic processGO:0030203110.425
Fly
regulation of innate immune responseGO:0045088710.416
Fly
positive regulation of cellular amide metabolic processGO:0034250260.402
Fly
regulation of peptidoglycan recognition protein signaling pathwayGO:006105840.398
Fly
regulation of immune system processGO:00026821760.397
Fly
peptide biosynthetic processGO:0043043420.376
Fly
positive regulation of production of molecular mediator of immune responseGO:0002702280.371
Fly
response to peptidoglycanGO:003249420.362
Fly
regulation of response to external stimulusGO:00321011150.324
Fly
response to virusGO:0009615280.322
Fly
regulation of response to stressGO:00801342000.314
Fly
immune response regulating signaling pathwayGO:000276420.311
Fly
cellular response to lipopolysaccharideGO:007122230.304
Fly
organonitrogen compound biosynthetic processGO:19015661170.290
Fly
negative regulation of defense responseGO:0031348350.286
Fly
negative regulation of signalingGO:00230572190.280
Fly
organonitrogen compound metabolic processGO:19015643180.256
Fly
positive regulation of immune effector processGO:0002699280.253
Fly
phenol containing compound metabolic processGO:0018958570.246
Fly
toll signaling pathwayGO:0008063250.231
positive regulation of immune system processGO:0002684680.224
Fly
positive regulation of melanization defense responseGO:003500810.222
pigment metabolic processGO:0042440840.210
Fly
cellular response to molecule of bacterial originGO:007121930.205
Fly
positive regulation of biosynthetic processGO:00098913160.195
Fly
positive regulation of nitrogen compound metabolic processGO:00511733540.178
Fly
negative regulation of immune system processGO:0002683500.158
Fly
regulation of toll signaling pathwayGO:0008592170.151
negative regulation of response to stimulusGO:00485852580.149
Fly
positive regulation of cellular biosynthetic processGO:00313283160.144
Fly
positive regulation of response to stimulusGO:00485843230.141
Fly
regulation of mapk cascadeGO:0043408920.133
Fly
aminoglycan catabolic processGO:000602660.132
Fly
regionalizationGO:00030024160.130
lipopolysaccharide mediated signaling pathwayGO:003166310.126
Fly
negative regulation of signal transductionGO:00099682060.124
Fly
intracellular signal transductionGO:00355563000.123
Fly
negative regulation of phosphate metabolic processGO:0045936450.123
Fly
killing of cells of other organismGO:003164010.121
hemolymph coagulationGO:0042381100.114
jnk cascadeGO:0007254500.112
Fly
negative regulation of defense response to bacteriumGO:190042570.110
Fly
negative regulation of cellular metabolic processGO:00313243820.109
Fly
phosphorylationGO:00163102940.108
Fly
regulation of cellular amide metabolic processGO:0034248390.107
Fly
dorsal ventral axis specificationGO:0009950660.106
stress activated mapk cascadeGO:0051403520.105
Fly
positive regulation of innate immune responseGO:0045089380.095
Fly
regulation of immune effector processGO:0002697520.094
Fly
axis specificationGO:00097981670.084
protein maturationGO:0051604710.082
agingGO:00075681430.080
Fly
negative regulation of intracellular signal transductionGO:1902532570.075
Fly
catabolic processGO:00090564090.072
Fly
regulation of stress activated mapk cascadeGO:0032872410.071
Fly
negative regulation of innate immune responseGO:0045824300.070
Fly
organic substance catabolic processGO:19015753080.069
Fly
regulation of intracellular signal transductionGO:19025312360.069
Fly
negative regulation of phosphorylationGO:0042326350.065
Fly
wound healingGO:0042060750.064
response to molecule of bacterial originGO:000223770.063
Fly
stress activated protein kinase signaling cascadeGO:0031098550.062
Fly
negative regulation of cell communicationGO:00106482230.060
Fly
determination of adult lifespanGO:00083401370.060
Fly
response to oxygen containing compoundGO:19017002000.059
Fly
carbohydrate derivative catabolic processGO:19011361180.058
Fly
response to endogenous stimulusGO:00097191190.058
Fly
cellular response to biotic stimulusGO:007121640.058
Fly
response to woundingGO:0009611940.057
response to lipopolysaccharideGO:003249640.057
Fly
carbohydrate derivative metabolic processGO:19011352170.054
Fly
regulation of jnk cascadeGO:0046328400.051
Fly
response to organonitrogen compoundGO:0010243750.050
Fly
organonitrogen compound catabolic processGO:19015651280.048
Fly
negative regulation of response to external stimulusGO:0032102220.044
Fly
appendage morphogenesisGO:00351073970.043
dorsal ventral pattern formationGO:00099531330.043
zymogen activationGO:0031638200.043
negative regulation of stress activated protein kinase signaling cascadeGO:0070303200.043
Fly
regulation of stress activated protein kinase signaling cascadeGO:0070302420.043
Fly
cellular amino acid metabolic processGO:0006520610.042
positive regulation of cell communicationGO:00106472500.040
negative regulation of mapk cascadeGO:0043409230.040
Fly
biological adhesionGO:00226101380.039
negative regulation of phosphorus metabolic processGO:0010563450.039
Fly
response to nitrogen compoundGO:1901698900.038
Fly
proteolysisGO:00065081920.038
aminoglycan metabolic processGO:0006022180.038
Fly
regulation of phosphorus metabolic processGO:00511742100.038
Fly
response to organic substanceGO:00100332840.037
Fly
multicellular organismal agingGO:00102591400.036
Fly
small molecule metabolic processGO:00442813050.036
mapk cascadeGO:00001651070.036
Fly
cell adhesionGO:00071551360.035
cellular response to oxygen containing compoundGO:1901701790.035
Fly
negative regulation of nitrogen compound metabolic processGO:00511722650.033
negative regulation of gene expressionGO:00106293870.033
growthGO:00400073590.032
cytolysisGO:001983510.032
protein processingGO:0016485680.032
imaginal disc derived appendage morphogenesisGO:00351143950.031
positive regulation of signalingGO:00230562430.031
positive regulation of signal transductionGO:00099672230.031
imaginal disc derived wing morphogenesisGO:00074763370.031
appendage developmentGO:00487364010.030
post embryonic appendage morphogenesisGO:00351203850.030
cellular response to lipidGO:0071396200.030
Fly
peptide hormone processingGO:001648620.029
regulation of phosphorylationGO:00423251470.029
Fly
cellular catabolic processGO:00442483720.028
negative regulation of protein metabolic processGO:0051248850.028
macromolecule catabolic processGO:00090571610.027
Fly
response to nutrient levelsGO:00316671140.027
cytolysis in other organismGO:005171510.027
response to protozoanGO:000156230.027
regulation of molecular functionGO:00650092170.027
endocytosisGO:00068973100.026
phagocytosisGO:00069092150.026
single organism biosynthetic processGO:00447112060.026
organophosphate metabolic processGO:00196371950.026
wing disc morphogenesisGO:00074723440.026
carboxylic acid metabolic processGO:0019752920.026
g protein coupled receptor signaling pathwayGO:00071861360.025
imaginal disc derived appendage developmentGO:00487373990.023
amine catabolic processGO:000931010.023
signal transduction by phosphorylationGO:00230141070.022
Fly
protein modification processGO:00362114380.022
regulation of catalytic activityGO:00507901850.022
chemotaxisGO:00069352490.022
oxoacid metabolic processGO:00434361030.022
cellular response to chemical stimulusGO:00708871990.021
Fly
synaptic transmissionGO:00072682880.021
developmental growthGO:00485892800.021
regulation of cell cycleGO:00517262910.021
regulation of peptidase activityGO:0052547390.021
columnar cuboidal epithelial cell differentiationGO:00020652560.021
cellular amine metabolic processGO:0044106120.021
vesicle mediated transportGO:00161923810.021
homeostatic processGO:00425921990.020
cellular protein modification processGO:00064644380.020
negative regulation of cellular protein metabolic processGO:0032269850.020
transcription from rna polymerase ii promoterGO:00063663680.020
disruption of cells of other organismGO:004436410.020
pyridine containing compound metabolic processGO:007252430.020
epithelial cell differentiationGO:00308553220.019
organic acid metabolic processGO:00060821030.019
body morphogenesisGO:001017120.019
amine metabolic processGO:0009308120.019
hormone metabolic processGO:0042445330.019
regulation of protein metabolic processGO:00512462560.019
respiratory system developmentGO:00605412130.019
salivary gland morphogenesisGO:00074351450.018
cell recognitionGO:00080371020.018
open tracheal system developmentGO:00074242040.018
gland morphogenesisGO:00226121450.017
cellular biogenic amine catabolic processGO:004240210.017
regulation of phosphate metabolic processGO:00192202100.017
Fly
cellular homeostasisGO:0019725800.017
response to organophosphorusGO:004668320.017
response to radiationGO:00093141550.017
negative regulation of growthGO:0045926840.017
chemical homeostasisGO:0048878920.017
negative regulation of endopeptidase activityGO:0010951110.017
axon developmentGO:00615642970.017
cellular ion homeostasisGO:0006873390.016
regulation of proteolysisGO:0030162870.016
melanotic encapsulation of foreign targetGO:0035011300.016
regulation of cell adhesionGO:0030155270.016
cell deathGO:00082192790.016
choline metabolic processGO:001969510.016
salivary gland developmentGO:00074311620.016
activation of immune responseGO:000225350.015
Fly
protein complex biogenesisGO:00702712010.015
single organism catabolic processGO:00447122280.015
response to abiotic stimulusGO:00096283410.015
synaptic target recognitionGO:0008039450.015
negative regulation of molecular functionGO:0044092510.015
organelle assemblyGO:00709251980.015
response to extracellular stimulusGO:00099911160.015
tissue deathGO:00162711020.015
columnar cuboidal epithelial cell developmentGO:00020662490.015
axonogenesisGO:00074092900.015
neurological system processGO:00508773580.015
chromosome segregationGO:00070591570.015
connective tissue developmentGO:006144830.015
spindle organizationGO:00070512530.015
cell cell junction organizationGO:0045216550.014
embryonic pattern specificationGO:00098801740.014
regulation of multicellular organismal developmentGO:20000264140.014
nuclear divisionGO:00002803320.014
forebrain developmentGO:003090020.014
regulation of cellular response to stressGO:0080135890.014
Fly
regulation of cellular amine metabolic processGO:003323830.014
negative regulation of developmental processGO:00510932010.014
organelle fissionGO:00482853400.014
camera type eye developmentGO:004301040.014
salivary gland histolysisGO:0035070880.014
negative regulation of multi organism processGO:0043901290.014
Fly
segmentationGO:00352822070.014
actin filament based processGO:00300292200.014
positive regulation of gene expressionGO:00106282900.013
regulation of cellular ketone metabolic processGO:001056530.013
macromolecular complex assemblyGO:00650032560.013
epithelial cell developmentGO:00020642740.013
tissue migrationGO:00901301550.013
gene silencingGO:00164581380.013
deathGO:00162652840.013
retina development in camera type eyeGO:006004140.013
single organism cell adhesionGO:0098602470.013
choline catabolic processGO:004242610.013
cell junction organizationGO:0034330570.013
ras protein signal transductionGO:0007265880.013
taxisGO:00423303040.013
positive regulation of phosphorus metabolic processGO:00105621390.013
regulation of growthGO:00400082330.013
cellular response to organic substanceGO:00713101320.013
Fly
regulation of hydrolase activityGO:0051336970.013
benzene containing compound metabolic processGO:004253730.013
establishment of localization in cellGO:00516494020.013
spermatogenesisGO:00072832000.013
positive regulation of cell migrationGO:003033520.013
anatomical structure homeostasisGO:0060249970.013
neuron projection guidanceGO:00974852410.013
heterocycle catabolic processGO:00467001660.013
coagulationGO:0050817100.012
regulation of transcription from rna polymerase ii promoterGO:00063573780.012
chaeta developmentGO:0022416970.012
negative regulation of catalytic activityGO:0043086420.012
regulation of cellular component biogenesisGO:00440872010.012
ovarian follicle cell developmentGO:00307072480.012
positive regulation of antifungal peptide biosynthetic processGO:000696750.012
non sensory hair organizationGO:0035316470.012
telencephalon developmentGO:002153720.012
positive regulation of cell motilityGO:200014730.012
response to temperature stimulusGO:00092661060.012
regulation of i kappab kinase nf kappab signalingGO:004312220.012
single organism cellular localizationGO:19025801800.012
cellular nitrogen compound catabolic processGO:00442701650.012
positive regulation of nucleobase containing compound metabolic processGO:00459353320.012
cation homeostasisGO:0055080510.012
male gamete generationGO:00482322010.012
posttranscriptional gene silencing by rnaGO:0035194450.012
cellular chemical homeostasisGO:0055082400.012
protein localizationGO:00081042840.012
regulation of anatomical structure morphogenesisGO:00226032420.012
gland developmentGO:00487321910.012
protein transportGO:00150311550.012
negative regulation of nucleic acid templated transcriptionGO:19035072400.011
nephron developmentGO:007200630.011
tube morphogenesisGO:00352391910.011
mitotic spindle organizationGO:00070522200.011
male mating behaviorGO:0060179700.011
single organismal cell cell adhesionGO:0016337450.011
nucleotide metabolic processGO:00091171610.011
nucleobase containing small molecule metabolic processGO:00550861740.011
aromatic compound catabolic processGO:00194391660.011
pyridine nucleotide metabolic processGO:001936220.011
positive regulation of intracellular signal transductionGO:19025331160.011
developmental programmed cell deathGO:00106231380.011
organic cyclic compound catabolic processGO:19013611680.011
regulation of cell differentiationGO:00455953020.011
negative regulation of immune responseGO:0050777390.011
Fly
establishment of protein localizationGO:00451841630.011
programmed cell deathGO:00125012570.011
nucleoside metabolic processGO:00091161270.011
regulation of tube architecture open tracheal systemGO:0035152680.011
autophagic cell deathGO:0048102830.011
mitotic nuclear divisionGO:00070672130.011
response to lipidGO:0033993380.011
Fly
small gtpase mediated signal transductionGO:0007264880.011
blastoderm segmentationGO:00073501590.011
eye developmentGO:00016543230.011
ethanolamine containing compound metabolic processGO:004243940.011
endomembrane system organizationGO:00102561190.011
posttranscriptional regulation of gene expressionGO:00106081450.011
positive regulation of macromolecule metabolic processGO:00106044050.011
developmental pigmentationGO:0048066680.010
acetylcholine metabolic processGO:000829120.010
nucleoside phosphate metabolic processGO:00067531620.010
oxidoreduction coenzyme metabolic processGO:000673320.010
regulation of anatomical structure sizeGO:00900661630.010
positive regulation of cellular component organizationGO:00511301560.010
cell divisionGO:00513012480.010
developmental maturationGO:00217001720.010
neurotransmitter metabolic processGO:004213320.010
intracellular transportGO:00469072280.010
regulation of cell substrate adhesionGO:001081020.010
maintenance of locationGO:0051235730.010
ion homeostasisGO:0050801550.010
negative regulation of cell differentiationGO:00455961430.010
organic hydroxy compound catabolic processGO:190161640.010

PGRP-SD disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.032
inherited metabolic disorderDOID:65500.013
disease of metabolismDOID:001466700.013
nervous system diseaseDOID:86300.013
disease of cellular proliferationDOID:1456600.011
cancerDOID:16200.011