Drosophila melanogaster

0 known processes

Mcr (Dmel_CG7586)

Macroglobulin complement-related

(Aliases: Dmel\CG7586,CG7586,anon-28DE,alpha-2-Mrp)

Mcr biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cell junction assemblyGO:0034329420.998
regulation of tube architecture open tracheal systemGO:0035152680.998
cell cell junction organizationGO:0045216550.997
establishment of blood brain barrierGO:0060856160.995
apical junction assemblyGO:0043297320.995
open tracheal system developmentGO:00074242040.994
cell junction organizationGO:0034330570.992
respiratory system developmentGO:00605412130.992
cell cell junction assemblyGO:0007043380.989
tissue morphogenesisGO:00487292970.981
embryonic morphogenesisGO:00485982060.948
regulation of tube size open tracheal systemGO:0035151430.937
morphogenesis of an epitheliumGO:00020092760.930
regulation of tube sizeGO:0035150460.910
axon developmentGO:00615642970.890
septate junction assemblyGO:0019991260.886
dorsal closureGO:0007391790.881
neuron projection guidanceGO:00974852410.819
tube morphogenesisGO:00352391910.817
morphogenesis of embryonic epitheliumGO:0016331940.807
extracellular matrix organizationGO:0030198320.804
axonogenesisGO:00074092900.778
cell motilityGO:00488702510.770
biological adhesionGO:00226101380.761
developmental growth involved in morphogenesisGO:0060560650.728
regulation of anatomical structure morphogenesisGO:00226032420.709
gliogenesisGO:0042063800.708
cell adhesionGO:00071551360.668
glial cell differentiationGO:0010001350.638
immune responseGO:00069552460.630
Fly
cell migrationGO:00164772380.606
establishment of glial blood brain barrierGO:0060857140.539
axon guidanceGO:00074112330.509
epithelial cell differentiationGO:00308553220.502
Mouse
central nervous system developmentGO:00074172010.494
protein modification processGO:00362114380.489
Mouse
regulation of tube length open tracheal systemGO:0035159240.458
regulation of cell differentiationGO:00455953020.446
Mouse
localization of cellGO:00516742570.415
response to biotic stimulusGO:00096072940.399
Fly
defense responseGO:00069523000.395
Fly
presynaptic membrane organizationGO:009709040.381
innate immune responseGO:00450871440.375
response to organic substanceGO:00100332840.344
negative regulation of cell differentiationGO:00455961430.340
regulation of multicellular organismal developmentGO:20000264140.319
Mouse
maintenance of locationGO:0051235730.315
immune system processGO:00023763470.313
Mouse Fly
protein localizationGO:00081042840.311
response to other organismGO:00517072930.308
Fly
extracellular structure organizationGO:0043062460.294
regulation of cell morphogenesisGO:00226041630.293
tube developmentGO:00352952440.281
head involutionGO:0008258350.277
ameboidal type cell migrationGO:00016671510.274
intracellular signal transductionGO:00355563000.257
positive regulation of protein metabolic processGO:00512471280.255
neuron projection extensionGO:1990138320.249
glial cell developmentGO:0021782270.243
ion transportGO:00068111450.235
regulation of anatomical structure sizeGO:00900661630.234
positive regulation of developmental processGO:00510941430.233
embryonic development via the syncytial blastodermGO:00017001480.230
protein complex biogenesisGO:00702712010.224
developmental maturationGO:00217001720.223
cellular protein modification processGO:00064644380.222
Mouse
response to woundingGO:0009611940.220
germ cell migrationGO:0008354430.220
branching involved in open tracheal system developmentGO:0060446450.209
meiotic cell cycleGO:00513211710.208
single organism carbohydrate metabolic processGO:0044723720.191
cellular macromolecule localizationGO:00707272200.189
regulation of response to external stimulusGO:00321011150.186
striated muscle cell developmentGO:0055002500.179
chemotaxisGO:00069352490.179
cellular response to oxygen containing compoundGO:1901701790.173
trachea developmentGO:0060438290.168
digestive system developmentGO:00551231490.165
response to organophosphorusGO:004668320.164
cell recognitionGO:00080371020.163
regulation of defense responseGO:00313471020.157
digestive tract developmentGO:00485651490.155
cation transportGO:00068121100.153
camera type eye developmentGO:004301040.148
carbohydrate derivative metabolic processGO:19011352170.144
single organism cellular localizationGO:19025801800.143
metal ion transportGO:0030001740.140
ovarian follicle cell developmentGO:00307072480.136
taxisGO:00423303040.130
ion transmembrane transportGO:00342201220.129
epithelial cell migrationGO:00106311480.128
regulation of cellular localizationGO:00603411360.126
response to radiationGO:00093141550.125
carbohydrate derivative biosynthetic processGO:1901137850.124
positive regulation of signal transductionGO:00099672230.123
regionalizationGO:00030024160.122
regulation of cell developmentGO:00602842150.121
regulation of cell shapeGO:00083601130.121
meiotic cell cycle processGO:19030461320.119
cellular response to chemical stimulusGO:00708871990.118
regulation of immune system processGO:00026821760.116
epithelial cell developmentGO:00020642740.114
cellular protein localizationGO:00346131600.114
striated muscle cell differentiationGO:0051146900.111
response to oxygen containing compoundGO:19017002000.108
telencephalon developmentGO:002153720.104
cell maturationGO:00484691440.102
single organism behaviorGO:00447083910.100
homeostatic processGO:00425921990.100
cellular catabolic processGO:00442483720.097
defense response to other organismGO:00985422250.090
Fly
immune response regulating signaling pathwayGO:000276420.090
skin developmentGO:0043588650.089
Mouse
protein transportGO:00150311550.088
protein complex assemblyGO:00064612000.088
response to organonitrogen compoundGO:0010243750.088
regulation of catalytic activityGO:00507901850.087
cellular component disassemblyGO:0022411460.086
response to external biotic stimulusGO:00432072930.086
Fly
axis specificationGO:00097981670.086
regulation of response to stressGO:00801342000.084
positive regulation of cellular component organizationGO:00511301560.084
protein localization to organelleGO:0033365820.083
regulation of cell cell adhesionGO:0022407210.081
protein complex disassemblyGO:0043241360.080
positive regulation of defense responseGO:0031349590.080
positive regulation of multicellular organismal processGO:00512401430.080
cell adhesion involved in heart morphogenesisGO:0061343120.079
single organismal cell cell adhesionGO:0016337450.079
endocytosisGO:00068973100.078
Fly
positive regulation of signalingGO:00230562430.077
ensheathment of neuronsGO:0007272100.077
body morphogenesisGO:001017120.076
protein importGO:0017038550.075
cell substrate adhesionGO:0031589100.074
single organism nuclear importGO:1902593510.073
neurological system processGO:00508773580.073
regulation of innate immune responseGO:0045088710.071
organophosphate metabolic processGO:00196371950.070
imaginal disc derived wing morphogenesisGO:00074763370.069
muscle cell differentiationGO:00426921030.069
response to hormoneGO:0009725450.068
regulation of cell adhesionGO:0030155270.066
regulation of axonogenesisGO:0050770320.066
organelle fissionGO:00482853400.065
synaptic transmissionGO:00072682880.065
response to lipopolysaccharideGO:003249640.065
cell migration involved in gastrulationGO:004207490.063
developmental growthGO:00485892800.063
innate immune response in mucosaGO:000222720.063
branching morphogenesis of an epithelial tubeGO:0048754450.063
heart morphogenesisGO:0003007320.062
regulation of actin cytoskeleton organizationGO:0032956420.061
positive regulation of phosphate metabolic processGO:00459371390.058
cellular response to organic substanceGO:00713101320.058
detection of stimulus involved in sensory perceptionGO:0050906920.058
response to endogenous stimulusGO:00097191190.058
mesodermal cell migrationGO:000807870.057
cellular response to endogenous stimulusGO:0071495800.057
cell activationGO:000177590.055
single organism biosynthetic processGO:00447112060.055
regulation of immune responseGO:00507761180.055
negative regulation of cell adhesionGO:000716290.054
morphogenesis of a branching structureGO:0001763450.053
embryo development ending in birth or egg hatchingGO:00097921520.053
carbohydrate metabolic processGO:0005975820.053
regulation of transportGO:00510491810.052
cellular component assembly involved in morphogenesisGO:00109271510.052
regulation of protein metabolic processGO:00512462560.052
Mouse
regulation of cellular response to stressGO:0080135890.052
negative regulation of multicellular organismal processGO:00512411420.051
brain developmentGO:00074201200.051
forebrain developmentGO:003090020.051
response to abiotic stimulusGO:00096283410.051
adult locomotory behaviorGO:0008344760.050
wing disc morphogenesisGO:00074723440.050
columnar cuboidal epithelial cell developmentGO:00020662490.049
protein modification by small protein conjugation or removalGO:00706471060.049
transmembrane transportGO:00550851390.049
gastrulationGO:0007369700.048
epithelial cell morphogenesis involved in gastrulationGO:000338170.048
nuclear transportGO:0051169720.048
axonal fasciculationGO:0007413120.048
axon ensheathmentGO:0008366100.048
negative regulation of developmental growthGO:0048640640.047
lipopolysaccharide mediated signaling pathwayGO:003166310.046
response to organic cyclic compoundGO:0014070890.046
post embryonic appendage morphogenesisGO:00351203850.045
learningGO:0007612750.044
cation homeostasisGO:0055080510.044
protein localization to nucleusGO:0034504550.044
establishment of protein localizationGO:00451841630.044
cellular response to hormone stimulusGO:0032870440.042
wound healingGO:0042060750.042
positive regulation of immune responseGO:0050778630.042
oocyte axis specificationGO:00073091080.041
regulation of mapk cascadeGO:0043408920.041
positive regulation of transportGO:0051050920.041
regulation of transferase activityGO:0051338580.040
negative regulation of signal transductionGO:00099682060.040
cellular response to peptideGO:1901653280.039
negative regulation of cell developmentGO:0010721620.039
tissue migrationGO:00901301550.037
wnt signaling pathwayGO:0016055980.036
positive regulation of developmental growthGO:0048639620.036
protein targeting to nucleusGO:0044744510.036
synaptic target recognitionGO:0008039450.036
protein phosphorylationGO:00064681690.035
Mouse
epidermis developmentGO:0008544650.035
Mouse
circulatory system developmentGO:0072359820.035
negative regulation of response to stimulusGO:00485852580.035
epithelium migrationGO:00901321480.034
regulation of tube diameterGO:0035296140.034
actin cytoskeleton organizationGO:00300362060.033
lateral inhibitionGO:00463312060.033
positive regulation of cell communicationGO:00106472500.033
regulation of localizationGO:00328792750.033
response to nitrogen compoundGO:1901698900.033
response to light stimulusGO:00094161240.033
negative regulation of developmental processGO:00510932010.033
regulation of cell projection organizationGO:0031344920.033
reproductive system developmentGO:0061458740.033
regulation of nervous system developmentGO:00519602480.032
regulation of cell morphogenesis involved in differentiationGO:0010769610.032
morphogenesis of a branching epitheliumGO:0061138450.032
retinal ganglion cell axon guidanceGO:0031290120.031
heart developmentGO:0007507820.031
regulation of cell sizeGO:0008361630.031
gland developmentGO:00487321910.031
establishment of protein localization to organelleGO:0072594620.030
cellular response to organonitrogen compoundGO:0071417360.030
phosphorylationGO:00163102940.030
Mouse
golgi organizationGO:0007030660.030
positive regulation of molecular functionGO:00440931360.030
negative regulation of cellular component organizationGO:00511291080.030
mesoderm developmentGO:0007498780.030
single organism cell adhesionGO:0098602470.029
positive regulation of response to stimulusGO:00485843230.029
cellular protein complex disassemblyGO:0043624350.029
regulation of multi organism processGO:00439001310.029
gastrulation with mouth forming firstGO:0001703360.028
cuticle developmentGO:0042335860.028
hemopoiesisGO:0030097460.027
Mouse
nucleotide metabolic processGO:00091171610.027
establishment or maintenance of polarity of follicular epitheliumGO:0016334260.027
columnar cuboidal epithelial cell differentiationGO:00020652560.027
glycoprotein biosynthetic processGO:0009101410.026
appendage developmentGO:00487364010.026
digestive tract morphogenesisGO:00485461270.026
retina development in camera type eyeGO:006004140.026
positive regulation of innate immune responseGO:0045089380.025
growthGO:00400073590.025
regulation of intracellular protein transportGO:0033157460.025
genitalia morphogenesisGO:0035112160.025
larval developmentGO:00021641040.025
regulation of intracellular signal transductionGO:19025312360.025
positive regulation of catalytic activityGO:00430851180.025
mapk cascadeGO:00001651070.024
endodermal cell differentiationGO:003598730.024
macromolecular complex assemblyGO:00650032560.024
regulation of response to biotic stimulusGO:0002831630.024
oocyte developmentGO:00485991240.023
endodermal cell fate commitmentGO:000171130.023
innate immune response activating signal transductionGO:000275820.023
regulation of molecular functionGO:00650092170.023
neuron recognitionGO:00080381010.022
carbohydrate derivative catabolic processGO:19011361180.022
apical constrictionGO:0003383180.022
signal transduction by phosphorylationGO:00230141070.022
zinc ion transportGO:000682950.021
regulation of phosphorylationGO:00423251470.021
Mouse
cell cell signaling involved in cell fate commitmentGO:00451682100.021
membrane organizationGO:00610241120.021
sensory perception of mechanical stimulusGO:0050954720.021
imaginal disc derived appendage developmentGO:00487373990.021
regulation of protein modification processGO:00313991120.021
Mouse
positive regulation of immune system processGO:0002684680.021
photoreceptor cell developmentGO:0042461960.021
transmission of nerve impulseGO:0019226120.020
heparan sulfate proteoglycan biosynthetic processGO:0015012100.020
nuclear importGO:0051170510.020
negative regulation of multi organism processGO:0043901290.020
interspecies interaction between organismsGO:0044419160.020
establishment of cell polarityGO:0030010400.020
regulation of symbiosis encompassing mutualism through parasitismGO:0043903150.020
protein modification by small protein conjugationGO:0032446790.020
organic substance transportGO:00717022570.019
cell growthGO:00160491080.018
exocrine system developmentGO:00352721620.018
cell adhesion mediated by integrinGO:0033627120.018
membrane biogenesisGO:004409180.018
adult behaviorGO:00305341370.018
hindbrain developmentGO:003090220.018
response to virusGO:0009615280.018
molting cycleGO:0042303560.018
Mouse
determination of adult lifespanGO:00083401370.018
positive regulation of cell differentiationGO:0045597640.018
positive regulation of axon extensionGO:004577320.018
intracellular transportGO:00469072280.018
action potentialGO:0001508130.017
lipid localizationGO:0010876540.017
mesenchymal cell developmentGO:001403110.017
axon extensionGO:0048675320.017
regulation of neuron projection developmentGO:0010975690.017
regulation of phosphorus metabolic processGO:00511742100.017
Mouse
positive regulation of protein localization to nucleusGO:1900182210.017
instar larval developmentGO:0002168550.017
organic hydroxy compound metabolic processGO:1901615830.017
regulation of dendrite morphogenesisGO:0048814280.016
cellular response to lipopolysaccharideGO:007122230.016
detection of light stimulusGO:0009583580.016
neuronal action potentialGO:0019228100.016
catabolic processGO:00090564090.016
regulation of tube diameter open tracheal systemGO:0035158110.016
regulation of hydrolase activityGO:0051336970.016
inorganic ion transmembrane transportGO:0098660730.016
adherens junction organizationGO:0034332270.016
detection of stimulusGO:00516061560.016
immune response activating signal transductionGO:000275720.015
locomotory behaviorGO:00076261760.015
positive regulation of phosphorylationGO:0042327870.015
negative regulation of rna metabolic processGO:00512532510.015
positive regulation of jun kinase activityGO:004350740.015
mesenchyme developmentGO:006048590.015
regulation of cellular catabolic processGO:00313291570.015
response to nutrient levelsGO:00316671140.015
cellular response to abiotic stimulusGO:0071214580.015
axis elongationGO:000340130.015
cellular response to nitrogen compoundGO:1901699510.015
negative regulation of response to external stimulusGO:0032102220.015
intracellular protein transportGO:00068861040.015
segmentationGO:00352822070.015
macromolecular complex disassemblyGO:0032984370.014
regulation of cell motilityGO:2000145230.014
regulation of hemocyte proliferationGO:0035206370.014
regulation of i kappab kinase nf kappab signalingGO:004312220.014
tube formationGO:0035148210.014
development of primary sexual characteristicsGO:0045137500.014
cellular amine metabolic processGO:0044106120.014
stem cell differentiationGO:00488631170.014
sex differentiationGO:0007548810.014
positive regulation of phosphorus metabolic processGO:00105621390.014
regulation of multicellular organism growthGO:0040014400.014
chitin based cuticle developmentGO:0040003490.014
actin mediated cell contractionGO:0070252210.014
imaginal disc growthGO:0007446370.014
cellular response to lipidGO:0071396200.014
positive regulation of cellular component biogenesisGO:0044089800.014
regulation of cellular component sizeGO:0032535980.014
nuclear divisionGO:00002803320.013
multicellular organism growthGO:0035264460.013
cardiovascular system developmentGO:0072358820.013
multicellular organismal signalingGO:0035637120.013
negative regulation of phosphate metabolic processGO:0045936450.013
Mouse
positive regulation of macromolecule metabolic processGO:00106044050.013
developmental cell growthGO:0048588520.013
regulation of cell substrate adhesionGO:001081020.013
regulation of protein targetingGO:1903533290.013
organelle localizationGO:00516401480.013
response to axon injuryGO:0048678120.012
mitochondrial membrane organizationGO:000700630.012
male genitalia developmentGO:0030539190.012
single organism intracellular transportGO:19025822070.012
ras protein signal transductionGO:0007265880.012
salivary gland developmentGO:00074311620.012
cellular response to organic cyclic compoundGO:0071407320.012
formation of primary germ layerGO:0001704240.012
negative regulation of cellular protein metabolic processGO:0032269850.012
Mouse
establishment or maintenance of cell polarityGO:00071631670.012
regulation of developmental growthGO:00486381740.012
synapse assemblyGO:00074161430.012
asymmetric protein localization involved in cell fate determinationGO:004516790.012
negative regulation of intrinsic apoptotic signaling pathwayGO:200124310.012
blastoderm segmentationGO:00073501590.012
negative regulation of signalingGO:00230572190.012
sarcomere organizationGO:0045214260.012
epithelial cell migration open tracheal systemGO:0007427320.012
social behaviorGO:003517640.012
response to lipidGO:0033993380.011
nephron developmentGO:007200630.011
regulation of embryonic cell shapeGO:0016476300.011
regulation of protein localizationGO:0032880760.011
microtubule based movementGO:0007018510.011
regulation of cytoplasmic transportGO:1903649470.011
activation of innate immune responseGO:000221840.011
positive regulation of growthGO:0045927750.011
mesenchymal cell differentiationGO:004876210.011
cytoplasmic transportGO:00164821300.011
regulation of purine nucleotide metabolic processGO:1900542620.011
regulation of protein complex assemblyGO:0043254420.011
chemosensory behaviorGO:00076351060.011
positive regulation of purine nucleotide catabolic processGO:0033123460.011
response to extracellular stimulusGO:00099911160.011
tissue homeostasisGO:0001894360.011
negative regulation of cell communicationGO:00106482230.011
nucleocytoplasmic transportGO:0006913720.011
basement membrane organizationGO:0071711100.011
regulation of actin polymerization or depolymerizationGO:0008064270.010
regulation of protein import into nucleusGO:0042306280.010
positive regulation of intracellular protein transportGO:0090316300.010
antimicrobial humoral responseGO:0019730990.010
Fly
positive regulation of intracellular signal transductionGO:19025331160.010
response to alcoholGO:0097305950.010
regulation of neuron differentiationGO:00456641030.010
vesicle mediated transportGO:00161923810.010
Fly
cellular protein complex assemblyGO:0043623710.010
positive regulation of protein modification processGO:0031401580.010
oocyte constructionGO:00073081120.010
positive regulation of cell morphogenesis involved in differentiationGO:0010770120.010
regulation of protein phosphorylationGO:0001932640.010
Mouse

Mcr disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.086
disease of cellular proliferationDOID:1456600.014
benign neoplasmDOID:006007200.014