Drosophila melanogaster

37 known processes

Pros54 (Dmel_CG7619)

Proteasome 54kD subunit

(Aliases: 7619,S5A,Rpn10/p54,CG7619,DmS5a,S5a,Dmel\CG7619,dRpn10,p54,Rpn10,mu-54)

Pros54 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
mitotic spindle organizationGO:00070522200.976
spindle assemblyGO:0051225800.906
proteolysisGO:00065081920.900
spindle assembly involved in mitosisGO:0090307500.809
modification dependent protein catabolic processGO:0019941780.650
Yeast Worm
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161540.624
mitotic spindle elongationGO:0000022810.621
cellular protein complex assemblyGO:0043623710.610
mitotic nuclear divisionGO:00070672130.608
spindle elongationGO:0051231830.566
regulation of molecular functionGO:00650092170.496
modification dependent macromolecule catabolic processGO:0043632790.474
Yeast Worm
microtubule cytoskeleton organization involved in mitosisGO:1902850520.474
catabolic processGO:00090564090.461
Yeast Worm
proteolysis involved in cellular protein catabolic processGO:0051603830.433
Yeast Worm
ubiquitin dependent protein catabolic processGO:0006511780.413
Yeast Worm
proteasomal protein catabolic processGO:0010498590.384
cellular catabolic processGO:00442483720.347
Yeast Worm
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434370.336
spindle organizationGO:00070512530.323
organelle assemblyGO:00709251980.313
chromosome segregationGO:00070591570.312
protein complex assemblyGO:00064612000.304
negative regulation of biosynthetic processGO:00098902770.297
negative regulation of macromolecule biosynthetic processGO:00105582700.288
negative regulation of cellular biosynthetic processGO:00313272770.283
protein complex biogenesisGO:00702712010.280
regulation of catabolic processGO:00098941700.272
taxisGO:00423303040.255
positive regulation of molecular functionGO:00440931360.247
negative regulation of cellular metabolic processGO:00313243820.245
protein modification by small protein conjugationGO:0032446790.204
protein catabolic processGO:00301631010.196
Yeast Worm
epithelial cell developmentGO:00020642740.194
negative regulation of signalingGO:00230572190.188
chromosome organizationGO:00512763600.174
dna repairGO:0006281540.167
organic substance catabolic processGO:19015753080.166
Yeast Worm
nucleotide metabolic processGO:00091171610.165
organelle fissionGO:00482853400.164
protein modification processGO:00362114380.159
mitotic sister chromatid segregationGO:0000070870.152
response to light stimulusGO:00094161240.151
regulation of endopeptidase activityGO:0052548360.140
purine nucleoside triphosphate metabolic processGO:00091441190.138
nuclear divisionGO:00002803320.137
heterocycle catabolic processGO:00467001660.133
ribose phosphate metabolic processGO:00196931450.132
defense responseGO:00069523000.131
nucleoside triphosphate metabolic processGO:00091411200.131
regulation of proteolysisGO:0030162870.130
nucleobase containing small molecule metabolic processGO:00550861740.127
positive regulation of hydrolase activityGO:0051345780.124
purine ribonucleotide catabolic processGO:00091541090.124
positive regulation of macromolecule metabolic processGO:00106044050.117
small molecule metabolic processGO:00442813050.115
protein ubiquitinationGO:0016567700.113
hematopoietic or lymphoid organ developmentGO:0048534570.112
purine containing compound catabolic processGO:00725231120.110
organophosphate catabolic processGO:00464341120.109
protein modification by small protein conjugation or removalGO:00706471060.109
cell migrationGO:00164772380.108
nucleotide catabolic processGO:00091661090.108
regulation of cellular protein metabolic processGO:00322682430.108
nucleobase containing compound catabolic processGO:00346551650.107
cell proliferationGO:00082832990.106
nuclear envelope organizationGO:000699870.105
positive regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032436190.103
regulation of cellular catabolic processGO:00313291570.103
regulation of hydrolase activityGO:0051336970.098
centrosome cycleGO:00070981370.096
cellular protein modification processGO:00064644380.096
cellular macromolecule catabolic processGO:00442651360.096
Yeast Worm
columnar cuboidal epithelial cell developmentGO:00020662490.093
purine ribonucleoside triphosphate catabolic processGO:00092071080.090
negative regulation of phosphorus metabolic processGO:0010563450.090
negative regulation of catalytic activityGO:0043086420.090
transcription from rna polymerase ii promoterGO:00063663680.088
regulation of mitotic cell cycleGO:00073461900.087
dna templated transcription elongationGO:0006354180.085
purine ribonucleotide metabolic processGO:00091501450.084
determination of adult lifespanGO:00083401370.083
Worm
macromolecule catabolic processGO:00090571610.083
Yeast Worm
ribonucleoside metabolic processGO:00091191270.083
positive regulation of proteasomal protein catabolic processGO:1901800200.082
response to radiationGO:00093141550.082
regulation of catalytic activityGO:00507901850.082
er associated ubiquitin dependent protein catabolic processGO:003043330.080
centrosome organizationGO:00512971630.080
purine nucleoside triphosphate catabolic processGO:00091461080.078
regulation of proteasomal protein catabolic processGO:0061136390.077
cellular response to dna damage stimulusGO:00069742230.075
negative regulation of multicellular organismal processGO:00512411420.075
Worm
multicellular organismal agingGO:00102591400.075
Worm
organic cyclic compound catabolic processGO:19013611680.074
columnar cuboidal epithelial cell differentiationGO:00020652560.073
positive regulation of catabolic processGO:00098961050.072
cell cycle comprising mitosis without cytokinesisGO:0033301250.072
negative regulation of molecular functionGO:0044092510.072
sister chromatid segregationGO:0000819920.070
negative regulation of signal transductionGO:00099682060.070
response to inorganic substanceGO:0010035440.070
secretion by cellGO:00329401010.069
larval developmentGO:00021641040.069
Worm
purine ribonucleoside triphosphate metabolic processGO:00092051190.069
regulation of mitosisGO:0007088560.069
negative regulation of gene expressionGO:00106293870.067
Worm
ribonucleoside triphosphate metabolic processGO:00091991190.065
positive regulation of nitrogen compound metabolic processGO:00511733540.062
neurological system processGO:00508773580.061
microtubule based transportGO:0010970420.061
cellular protein catabolic processGO:0044257830.061
Yeast Worm
anterior posterior pattern specificationGO:00099521360.061
regulation of protein metabolic processGO:00512462560.059
purine ribonucleoside catabolic processGO:00461301120.059
establishment of cell polarityGO:0030010400.059
organonitrogen compound metabolic processGO:19015643180.059
neuron projection guidanceGO:00974852410.059
epithelial cell differentiationGO:00308553220.059
wnt signaling pathwayGO:0016055980.057
cellular macromolecular complex assemblyGO:00346221530.056
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052240.055
purine nucleotide catabolic processGO:00061951090.054
cell deathGO:00082192790.054
regulation of mitotic sister chromatid segregationGO:0033047280.054
response to organic substanceGO:00100332840.053
nucleoside phosphate catabolic processGO:19012921100.053
negative regulation of cellular protein metabolic processGO:0032269850.053
embryo development ending in birth or egg hatchingGO:00097921520.052
lymph gland developmentGO:0048542280.052
positive regulation of gene expressionGO:00106282900.051
ribonucleotide catabolic processGO:00092611090.050
purine nucleoside catabolic processGO:00061521120.049
ribonucleoside catabolic processGO:00424541120.049
carbohydrate derivative catabolic processGO:19011361180.049
immune responseGO:00069552460.049
nucleoside metabolic processGO:00091161270.048
cellular nitrogen compound catabolic processGO:00442701650.047
regulation of nucleoside metabolic processGO:0009118500.045
ribonucleotide metabolic processGO:00092591450.044
negative regulation of response to stimulusGO:00485852580.043
regulation of protein modification processGO:00313991120.043
single organism catabolic processGO:00447122280.043
regulation of transcription from rna polymerase ii promoterGO:00063573780.042
lateral inhibitionGO:00463312060.042
nucleoside phosphate metabolic processGO:00067531620.042
cellular response to chemical stimulusGO:00708871990.042
ribonucleoside triphosphate catabolic processGO:00092031080.042
head developmentGO:00603221350.041
regulation of gtpase activityGO:0043087440.041
multi organism behaviorGO:00517051750.041
regulation of peptidase activityGO:0052547390.041
mitotic cell cycle phase transitionGO:00447721380.040
purine nucleoside metabolic processGO:00422781270.040
organonitrogen compound catabolic processGO:19015651280.039
organophosphate metabolic processGO:00196371950.039
cell type specific apoptotic processGO:0097285380.038
regulation of response to stressGO:00801342000.038
establishment of spindle localizationGO:0051293220.038
central nervous system developmentGO:00074172010.037
glycosyl compound catabolic processGO:19016581120.037
wing disc morphogenesisGO:00074723440.037
aromatic compound catabolic processGO:00194391660.036
locomotory behaviorGO:00076261760.035
dna packagingGO:0006323910.035
growthGO:00400073590.035
synaptic vesicle recyclingGO:0036465280.035
sensory organ morphogenesisGO:00905962600.034
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.034
positive regulation of proteolysisGO:0045862520.033
purine ribonucleoside metabolic processGO:00461281270.033
regulation of multicellular organismal developmentGO:20000264140.032
Worm
gene silencingGO:00164581380.032
Worm
regulation of cell cycleGO:00517262910.032
positive regulation of transcription dna templatedGO:00458932660.032
positive regulation of cellular catabolic processGO:0031331950.031
regulation of cellular component biogenesisGO:00440872010.031
gtp metabolic processGO:0046039720.031
detection of stimulusGO:00516061560.031
developmental growthGO:00485892800.030
anterior posterior axis specificationGO:00099481090.030
transcription elongation from rna polymerase ii promoterGO:0006368180.029
regulation of synapse assemblyGO:0051963940.029
neuromuscular synaptic transmissionGO:0007274670.029
cellular component assembly involved in morphogenesisGO:00109271510.029
regulation of protein complex assemblyGO:0043254420.028
regulation of phosphate metabolic processGO:00192202100.028
body morphogenesisGO:001017120.028
purine nucleotide metabolic processGO:00061631460.027
negative regulation of nitrogen compound metabolic processGO:00511722650.026
imaginal disc derived appendage morphogenesisGO:00351143950.026
regulation of protein catabolic processGO:0042176550.026
agingGO:00075681430.026
Worm
nucleoside catabolic processGO:00091641120.026
positive regulation of nucleobase containing compound metabolic processGO:00459353320.026
regulation of organ morphogenesisGO:2000027780.026
ovarian follicle cell developmentGO:00307072480.026
response to peptideGO:1901652290.025
blastoderm segmentationGO:00073501590.025
chemotaxisGO:00069352490.025
positive regulation of endopeptidase activityGO:0010950260.025
negative regulation of phosphate metabolic processGO:0045936450.024
double strand break repairGO:0006302260.024
nucleoside triphosphate catabolic processGO:00091431080.024
axon cargo transportGO:0008088290.024
regulation of proteolysis involved in cellular protein catabolic processGO:1903050440.024
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.024
guanosine containing compound catabolic processGO:1901069740.024
negative regulation of rna biosynthetic processGO:19026792400.023
positive regulation of nucleoside metabolic processGO:0045979470.023
cellular response to endogenous stimulusGO:0071495800.023
positive regulation of protein metabolic processGO:00512471280.023
regulation of phosphorus metabolic processGO:00511742100.023
negative regulation of nucleic acid templated transcriptionGO:19035072400.023
dna metabolic processGO:00062592270.023
positive regulation of cellular protein metabolic processGO:00322701180.023
regulation of gtp catabolic processGO:0033124440.022
embryonic axis specificationGO:00005781070.022
regulation of apoptotic processGO:00429811300.022
telencephalon developmentGO:002153720.022
negative regulation of developmental growthGO:0048640640.022
fertilizationGO:0009566260.022
deathGO:00162652840.022
positive regulation of biosynthetic processGO:00098913160.021
programmed cell deathGO:00125012570.021
negative regulation of cell communicationGO:00106482230.021
chaperone mediated protein foldingGO:006107720.021
vesicle mediated transportGO:00161923810.021
protein deubiquitinationGO:0016579170.021
appendage morphogenesisGO:00351073970.021
positive regulation of catalytic activityGO:00430851180.021
regulation of purine nucleotide catabolic processGO:0033121480.021
protein maturationGO:0051604710.020
axon guidanceGO:00074112330.020
cell motilityGO:00488702510.020
positive regulation of protein catabolic processGO:0045732340.020
eye developmentGO:00016543230.020
protein processingGO:0016485680.019
tripartite regional subdivisionGO:00073511030.019
anterior posterior axis specification embryoGO:00085951030.019
response to peptide hormoneGO:0043434290.019
positive regulation of phosphorus metabolic processGO:00105621390.019
mitotic g2 dna damage checkpointGO:0007095690.018
regulation of nucleotide metabolic processGO:0006140620.018
lipid localizationGO:0010876540.018
glycosyl compound metabolic processGO:19016571270.018
purine nucleoside monophosphate metabolic processGO:0009126500.018
mitotic sister chromatid separationGO:0051306300.017
positive regulation of purine nucleotide catabolic processGO:0033123460.017
regulation of growthGO:00400082330.016
organelle localizationGO:00516401480.016
negative regulation of protein metabolic processGO:0051248850.016
regulation of cell morphogenesis involved in differentiationGO:0010769610.016
negative regulation of cell proliferationGO:0008285690.016
endocytosisGO:00068973100.016
chromosome separationGO:0051304420.016
protein neddylationGO:004511650.016
regulation of innate immune responseGO:0045088710.016
detection of stimulus involved in sensory perceptionGO:0050906920.016
protein transportGO:00150311550.016
regulation of wnt signaling pathwayGO:0030111680.015
positive regulation of peptidase activityGO:0010952290.015
photoreceptor cell differentiationGO:00465301700.015
small gtpase mediated signal transductionGO:0007264880.015
positive regulation of cell deathGO:0010942690.015
axon developmentGO:00615642970.015
positive regulation of macromolecule biosynthetic processGO:00105572830.015
microtubule organizing center organizationGO:00310231680.015
striated muscle cell differentiationGO:0051146900.015
regulation of mitotic sister chromatid separationGO:0010965280.015
ras protein signal transductionGO:0007265880.015
larval behaviorGO:0030537420.015
regulation of ras protein signal transductionGO:0046578930.015
cellular response to nitrogen compoundGO:1901699510.015
axis specificationGO:00097981670.015
protein phosphorylationGO:00064681690.015
macromolecular complex assemblyGO:00650032560.015
imaginal disc derived appendage developmentGO:00487373990.014
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic processGO:0031145300.014
maternal determination of anterior posterior axis embryoGO:0008358740.014
negative regulation of sequence specific dna binding transcription factor activityGO:004343340.014
metaphase anaphase transition of cell cycleGO:0044784280.014
centriole assemblyGO:0098534240.014
negative regulation of nucleobase containing compound metabolic processGO:00459342610.014
positive regulation of nucleotide metabolic processGO:0045981550.014
male gamete generationGO:00482322010.013
Worm
positive regulation of cellular biosynthetic processGO:00313283160.013
eye morphogenesisGO:00485922600.013
organic substance transportGO:00717022570.013
response to endogenous stimulusGO:00097191190.013
compound eye developmentGO:00487493070.013
establishment of protein localizationGO:00451841630.013
regulation of programmed cell deathGO:00430671520.013
chromatin organizationGO:00063252070.013
transition metal ion transportGO:0000041160.013
positive regulation of rna metabolic processGO:00512542710.013
establishment or maintenance of apical basal cell polarityGO:0035088340.013
compound eye morphogenesisGO:00017452490.013
protein modification by small protein removalGO:0070646280.013
regulation of chromosome organizationGO:0033044640.013
positive regulation of gtp catabolic processGO:0033126430.013
sex differentiationGO:0007548810.012
regionalizationGO:00030024160.012
purine ribonucleoside monophosphate metabolic processGO:0009167500.012
brain developmentGO:00074201200.012
positive regulation of cellular component biogenesisGO:0044089800.012
rna polymerase ii transcriptional preinitiation complex assemblyGO:0051123200.012
positive regulation of rna biosynthetic processGO:19026802660.012
guanosine containing compound metabolic processGO:1901068740.012
innate immune responseGO:00450871440.012
axonogenesisGO:00074092900.012
reproductive system developmentGO:0061458740.012
cell maturationGO:00484691440.012
tube developmentGO:00352952440.012
regulation of striated muscle contractionGO:000694220.012
negative regulation of cell deathGO:0060548810.012
regulation of developmental growthGO:00486381740.012
protein alkylationGO:0008213430.012
forebrain developmentGO:003090020.011
rhabdomere developmentGO:0042052380.011
tube morphogenesisGO:00352391910.011
positive regulation of purine nucleotide metabolic processGO:1900544550.011
cellular response to organic substanceGO:00713101320.011
negative regulation of protein phosphorylationGO:0001933170.011
protein secretionGO:0009306450.011
cell divisionGO:00513012480.011
negative regulation of defense responseGO:0031348350.011
negative regulation of gene expression epigeneticGO:0045814770.011
cellular component maintenanceGO:0043954230.011
protein polymerizationGO:0051258420.011
ion transportGO:00068111450.011
imaginal disc derived wing morphogenesisGO:00074763370.011
centriole replicationGO:0007099240.011
positive regulation of gtpase activityGO:0043547430.011
dephosphorylationGO:0016311510.011
establishment of organelle localizationGO:00516561220.011
protein localizationGO:00081042840.011
histone lysine methylationGO:0034968320.011
apoptotic process involved in morphogenesisGO:006056130.010
regulation of organelle organizationGO:00330431960.010
establishment of localization in cellGO:00516494020.010
purine nucleoside monophosphate catabolic processGO:0009128380.010
regulation of immune responseGO:00507761180.010

Pros54 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org