Drosophila melanogaster

13 known processes

Gie (Dmel_CG7891)

novel GTPase indispensable for equal segregation of chromosomes

(Aliases: Arl8,BcDNA:LD29185,CG7891,Dmel\CG7891)

Gie biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
purine ribonucleoside metabolic processGO:00461281270.507
purine ribonucleoside triphosphate metabolic processGO:00092051190.366
positive regulation of macromolecule metabolic processGO:00106044050.331
nucleoside triphosphate metabolic processGO:00091411200.287
defense response to other organismGO:00985422250.275
guanosine containing compound catabolic processGO:1901069740.271
purine nucleotide catabolic processGO:00061951090.270
autophagyGO:00069141080.265
establishment of organelle localizationGO:00516561220.231
organelle assemblyGO:00709251980.211
purine ribonucleoside triphosphate catabolic processGO:00092071080.205
organelle localizationGO:00516401480.195
immune system processGO:00023763470.194
vesicle mediated transportGO:00161923810.192
ribonucleoside triphosphate catabolic processGO:00092031080.181
purine nucleoside catabolic processGO:00061521120.179
cell projection assemblyGO:0030031940.178
purine nucleoside triphosphate catabolic processGO:00091461080.177
nucleotide catabolic processGO:00091661090.172
ribonucleoside catabolic processGO:00424541120.171
cellular catabolic processGO:00442483720.162
nucleoside catabolic processGO:00091641120.162
nucleoside triphosphate catabolic processGO:00091431080.159
ribonucleotide catabolic processGO:00092611090.150
programmed cell deathGO:00125012570.146
purine containing compound catabolic processGO:00725231120.143
nucleoside metabolic processGO:00091161270.143
aromatic compound catabolic processGO:00194391660.139
biological adhesionGO:00226101380.138
growthGO:00400073590.138
regulation of organelle organizationGO:00330431960.137
response to biotic stimulusGO:00096072940.135
carbohydrate derivative catabolic processGO:19011361180.134
endocytosisGO:00068973100.134
gtp metabolic processGO:0046039720.133
muscle structure developmentGO:00610612240.132
regulation of response to stressGO:00801342000.132
nucleoside phosphate catabolic processGO:19012921100.130
cell divisionGO:00513012480.129
regulation of catabolic processGO:00098941700.121
single organism membrane fusionGO:0044801420.121
positive regulation of cellular component organizationGO:00511301560.121
cell proliferationGO:00082832990.118
regulation of cellular catabolic processGO:00313291570.114
morphogenesis of an epitheliumGO:00020092760.114
axonogenesisGO:00074092900.114
embryo development ending in birth or egg hatchingGO:00097921520.112
proteolysisGO:00065081920.111
dna repairGO:0006281540.111
protein modification processGO:00362114380.108
response to other organismGO:00517072930.107
protein complex biogenesisGO:00702712010.105
response to external biotic stimulusGO:00432072930.105
catabolic processGO:00090564090.103
protein complex assemblyGO:00064612000.103
nucleobase containing compound catabolic processGO:00346551650.102
purine ribonucleotide catabolic processGO:00091541090.100
ribonucleoside metabolic processGO:00091191270.097
establishment of vesicle localizationGO:0051650510.096
organonitrogen compound catabolic processGO:19015651280.094
purine nucleotide metabolic processGO:00061631460.093
purine ribonucleotide metabolic processGO:00091501450.090
intracellular signal transductionGO:00355563000.090
nucleoside phosphate metabolic processGO:00067531620.089
actin filament based processGO:00300292200.088
negative regulation of cell communicationGO:00106482230.087
deathGO:00162652840.087
organonitrogen compound metabolic processGO:19015643180.087
ribonucleotide metabolic processGO:00092591450.086
heterocycle catabolic processGO:00467001660.085
purine nucleoside triphosphate metabolic processGO:00091441190.081
defense responseGO:00069523000.081
cilium morphogenesisGO:0060271390.081
imaginal disc derived appendage developmentGO:00487373990.080
negative regulation of response to stimulusGO:00485852580.079
nucleobase containing small molecule metabolic processGO:00550861740.078
glycosyl compound metabolic processGO:19016571270.078
appendage morphogenesisGO:00351073970.078
gtp catabolic processGO:0006184720.078
single organism intracellular transportGO:19025822070.077
negative regulation of signalingGO:00230572190.076
negative regulation of cellular biosynthetic processGO:00313272770.076
vesicle localizationGO:0051648550.075
cellular nitrogen compound catabolic processGO:00442701650.074
cellular protein modification processGO:00064644380.074
cell deathGO:00082192790.074
organic substance catabolic processGO:19015753080.073
purine containing compound metabolic processGO:00725211550.073
regulation of nervous system developmentGO:00519602480.072
glycosyl compound catabolic processGO:19016581120.071
axon guidanceGO:00074112330.071
positive regulation of protein metabolic processGO:00512471280.071
guanosine containing compound metabolic processGO:1901068740.071
regulation of cellular protein metabolic processGO:00322682430.070
response to bacteriumGO:00096171980.069
purine nucleoside metabolic processGO:00422781270.069
ribose phosphate metabolic processGO:00196931450.068
nucleotide metabolic processGO:00091171610.068
developmental growthGO:00485892800.066
establishment of localization in cellGO:00516494020.066
imaginal disc derived appendage morphogenesisGO:00351143950.065
regulation of cytoskeleton organizationGO:0051493890.065
cytoplasmic transportGO:00164821300.064
single organism catabolic processGO:00447122280.061
regulation of cellular response to stressGO:0080135890.059
apoptotic processGO:00069151590.059
regulation of cell morphogenesisGO:00226041630.057
cytokinesisGO:0000910900.056
tissue morphogenesisGO:00487292970.056
regulation of multi organism processGO:00439001310.055
regulation of cellular component biogenesisGO:00440872010.054
organic substance transportGO:00717022570.054
cellular response to dna damage stimulusGO:00069742230.054
positive regulation of nitrogen compound metabolic processGO:00511733540.054
synapse organizationGO:00508081960.053
epithelial cell developmentGO:00020642740.053
negative regulation of signal transductionGO:00099682060.052
transcription from rna polymerase ii promoterGO:00063663680.051
regulation of programmed cell deathGO:00430671520.051
cell cell signaling involved in cell fate commitmentGO:00451682100.051
regulation of cell shapeGO:00083601130.051
regulation of growthGO:00400082330.051
taxisGO:00423303040.051
establishment of protein localizationGO:00451841630.050
response to oxygen containing compoundGO:19017002000.050
intracellular transportGO:00469072280.049
cell adhesionGO:00071551360.049
ribonucleoside triphosphate metabolic processGO:00091991190.049
organophosphate catabolic processGO:00464341120.049
regulation of protein metabolic processGO:00512462560.049
lateral inhibitionGO:00463312060.049
eye developmentGO:00016543230.048
embryonic organ developmentGO:0048568500.048
posttranscriptional regulation of gene expressionGO:00106081450.047
endosomal transportGO:0016197440.047
single organism membrane organizationGO:0044802930.047
purine ribonucleoside catabolic processGO:00461301120.046
single organism cellular localizationGO:19025801800.046
positive regulation of nucleobase containing compound metabolic processGO:00459353320.045
regulation of molecular functionGO:00650092170.045
regulation of neurogenesisGO:00507671580.044
macromolecular complex assemblyGO:00650032560.043
wing disc morphogenesisGO:00074723440.043
cell cycle checkpointGO:0000075950.043
compound eye developmentGO:00487493070.043
regulation of anatomical structure morphogenesisGO:00226032420.042
atp catabolic processGO:0006200380.042
regulation of cell cycle phase transitionGO:19019871300.042
protein transportGO:00150311550.041
regulation of cell differentiationGO:00455953020.041
positive regulation of phosphorus metabolic processGO:00105621390.040
regulation of intracellular signal transductionGO:19025312360.040
cell cycle phase transitionGO:00447701400.039
positive regulation of biosynthetic processGO:00098913160.039
meiotic cell cycleGO:00513211710.039
regulation of catalytic activityGO:00507901850.038
positive regulation of purine nucleotide metabolic processGO:1900544550.038
regulation of protein stabilityGO:0031647430.038
cellular protein localizationGO:00346131600.037
larval developmentGO:00021641040.037
cellular response to chemical stimulusGO:00708871990.037
phagocytosisGO:00069092150.037
wnt signaling pathwayGO:0016055980.037
positive regulation of phosphate metabolic processGO:00459371390.037
positive regulation of cellular biosynthetic processGO:00313283160.037
cellular protein complex assemblyGO:0043623710.037
regulation of cell cycleGO:00517262910.036
muscle cell differentiationGO:00426921030.036
appendage developmentGO:00487364010.035
actin cytoskeleton organizationGO:00300362060.035
stress activated protein kinase signaling cascadeGO:0031098550.034
gland developmentGO:00487321910.033
defense response to bacteriumGO:00427421780.033
sensory organ morphogenesisGO:00905962600.032
membrane organizationGO:00610241120.032
regulation of response to external stimulusGO:00321011150.032
ribonucleoside monophosphate catabolic processGO:0009158390.032
cilium assemblyGO:0042384380.032
positive regulation of multicellular organismal processGO:00512401430.031
stem cell differentiationGO:00488631170.031
regulation of multicellular organismal developmentGO:20000264140.031
mitotic cell cycle phase transitionGO:00447721380.031
carbohydrate derivative metabolic processGO:19011352170.031
regulation of phosphate metabolic processGO:00192202100.031
cellular macromolecule localizationGO:00707272200.030
positive regulation of cellular catabolic processGO:0031331950.030
body morphogenesisGO:001017120.030
small molecule metabolic processGO:00442813050.030
regulation of cell proliferationGO:00421271630.030
positive regulation of catalytic activityGO:00430851180.029
regionalizationGO:00030024160.029
positive regulation of catabolic processGO:00098961050.029
post embryonic appendage morphogenesisGO:00351203850.029
response to organic substanceGO:00100332840.029
dna integrity checkpointGO:0031570810.029
regulation of response to biotic stimulusGO:0002831630.028
regulation of phosphorus metabolic processGO:00511742100.028
regulation of cell cycle processGO:00105641810.028
synaptic transmissionGO:00072682880.027
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.027
membrane fusionGO:0061025420.027
digestive system developmentGO:00551231490.027
protein localizationGO:00081042840.027
response to abiotic stimulusGO:00096283410.027
neurotransmitter transportGO:0006836370.027
epithelial cell differentiationGO:00308553220.027
regulation of proteolysisGO:0030162870.026
negative regulation of nitrogen compound metabolic processGO:00511722650.026
negative regulation of cell cycle phase transitionGO:19019881030.026
immune effector processGO:0002252980.026
positive regulation of lyase activityGO:0051349100.025
vesicle organizationGO:0016050440.025
regulation of cell developmentGO:00602842150.024
cilium organizationGO:0044782410.024
regulation of neuron differentiationGO:00456641030.024
hematopoietic or lymphoid organ developmentGO:0048534570.024
protein catabolic processGO:00301631010.024
dna metabolic processGO:00062592270.024
meiotic nuclear divisionGO:00071261510.023
regulation of cellular ketone metabolic processGO:001056530.023
nitrogen compound transportGO:0071705850.023
chromosome organizationGO:00512763600.023
centrosome cycleGO:00070981370.023
response to nitrogen compoundGO:1901698900.023
embryonic morphogenesisGO:00485982060.023
ovarian follicle cell developmentGO:00307072480.023
stress activated mapk cascadeGO:0051403520.023
positive regulation of cellular component biogenesisGO:0044089800.023
actin filament organizationGO:00070151260.022
regulation of developmental growthGO:00486381740.022
imaginal disc derived wing morphogenesisGO:00074763370.022
gland morphogenesisGO:00226121450.022
negative regulation of macromolecule biosynthetic processGO:00105582700.021
regulation of cell deathGO:00109411730.021
negative regulation of cell proliferationGO:0008285690.021
negative regulation of developmental processGO:00510932010.021
stem cell developmentGO:0048864790.021
chemotaxisGO:00069352490.021
establishment of planar polarityGO:0001736870.021
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.020
organic cyclic compound catabolic processGO:19013611680.020
enzyme linked receptor protein signaling pathwayGO:00071671790.020
leg disc developmentGO:0035218920.020
negative regulation of nucleic acid templated transcriptionGO:19035072400.020
regulation of protein modification processGO:00313991120.020
positive regulation of signalingGO:00230562430.020
regulation of transportGO:00510491810.020
chromatin modificationGO:00165681470.020
immune system developmentGO:0002520570.020
dna damage checkpointGO:0000077780.020
compound eye morphogenesisGO:00017452490.020
cellular component assembly involved in morphogenesisGO:00109271510.019
negative regulation of biosynthetic processGO:00098902770.019
positive regulation of nervous system developmentGO:0051962690.019
tor signalingGO:0031929320.019
positive regulation of proteolysisGO:0045862520.019
cellular response to oxygen containing compoundGO:1901701790.019
establishment or maintenance of cell polarityGO:00071631670.019
positive regulation of developmental processGO:00510941430.019
cellular macromolecular complex assemblyGO:00346221530.019
positive regulation of cellular protein metabolic processGO:00322701180.019
homeostatic processGO:00425921990.019
establishment of tissue polarityGO:0007164870.019
intracellular protein transportGO:00068861040.018
positive regulation of hydrolase activityGO:0051345780.018
covalent chromatin modificationGO:00165691060.018
negative regulation of cell cycleGO:00457861160.018
positive regulation of molecular functionGO:00440931360.018
response to endogenous stimulusGO:00097191190.018
jnk cascadeGO:0007254500.018
membrane buddingGO:000690040.018
regulation of notch signaling pathwayGO:00085931000.018
cell cycle g1 s phase transitionGO:0044843310.018
negative regulation of transcription dna templatedGO:00458922370.017
positive regulation of cell communicationGO:00106472500.017
meiotic cell cycle processGO:19030461320.017
negative regulation of cellular protein metabolic processGO:0032269850.017
cellular macromolecule catabolic processGO:00442651360.017
regulation of mitotic cell cycleGO:00073461900.017
regulation of transcription from rna polymerase ii promoterGO:00063573780.017
cortical actin cytoskeleton organizationGO:0030866240.017
cellular protein catabolic processGO:0044257830.017
neurotransmitter secretionGO:0007269350.017
negative regulation of cellular metabolic processGO:00313243820.017
axon developmentGO:00615642970.017
nuclear divisionGO:00002803320.017
regulation of protein phosphorylationGO:0001932640.017
regulation of nucleoside metabolic processGO:0009118500.017
exocytosisGO:0006887280.017
neuron projection guidanceGO:00974852410.016
regulation of hydrolase activityGO:0051336970.016
columnar cuboidal epithelial cell developmentGO:00020662490.016
response to organonitrogen compoundGO:0010243750.016
salivary gland developmentGO:00074311620.016
secretionGO:00469031090.016
regulation of synapse structure and activityGO:00508031280.016
epidermal growth factor receptor signaling pathwayGO:0007173580.016
erbb signaling pathwayGO:0038127580.016
localization of cellGO:00516742570.016
regulation of cell projection organizationGO:0031344920.016
negative regulation of intracellular signal transductionGO:1902532570.016
regulation of hemocyte proliferationGO:0035206370.016
regulation of apoptotic processGO:00429811300.015
purine nucleoside monophosphate catabolic processGO:0009128380.015
eye morphogenesisGO:00485922600.015
reproductive structure developmentGO:0048608740.015
regulation of immune system processGO:00026821760.015
protein modification by small protein conjugation or removalGO:00706471060.015
neuron remodelingGO:0016322290.015
vesicle fusionGO:0006906190.015
columnar cuboidal epithelial cell differentiationGO:00020652560.015
macromolecule catabolic processGO:00090571610.015
synapse assemblyGO:00074161430.014
proteolysis involved in cellular protein catabolic processGO:0051603830.014
negative regulation of rna metabolic processGO:00512532510.014
negative regulation of nucleobase containing compound metabolic processGO:00459342610.014
negative regulation of rna biosynthetic processGO:19026792400.014
negative regulation of programmed cell deathGO:0043069720.014
cellular response to nutrient levelsGO:0031669620.014
cellular response to endogenous stimulusGO:0071495800.014
cell motilityGO:00488702510.014
organophosphate metabolic processGO:00196371950.014
response to extracellular stimulusGO:00099911160.014
cytoskeleton dependent cytokinesisGO:0061640810.014
developmental maturationGO:00217001720.014
negative regulation of protein metabolic processGO:0051248850.013
nucleocytoplasmic transportGO:0006913720.013
spermatid differentiationGO:00485151140.013
macroautophagyGO:0016236420.013
negative regulation of cell differentiationGO:00455961430.013
striated muscle cell differentiationGO:0051146900.013
pronuclear migrationGO:003504640.013
circulatory system developmentGO:0072359820.013
mitotic cytokinesisGO:0000281500.013
regulation of neuron projection developmentGO:0010975690.013
negative regulation of mitotic cell cycle phase transitionGO:19019911030.013
notch signaling pathwayGO:00072191200.013
signal releaseGO:0023061490.013
regulation of nucleotide metabolic processGO:0006140620.013
positive regulation of response to stimulusGO:00485843230.013
production of molecular mediator of immune responseGO:0002440460.013
regulation of nucleotide catabolic processGO:0030811480.013
negative regulation of phosphorylationGO:0042326350.013
protein dna complex subunit organizationGO:0071824860.013
mitotic dna integrity checkpointGO:0044774750.013
g1 s transition of mitotic cell cycleGO:0000082310.013
regulation of meiosisGO:004002030.012
centrosome organizationGO:00512971630.012
photoreceptor cell differentiationGO:00465301700.012
golgi vesicle transportGO:0048193270.012
cell growthGO:00160491080.012
positive regulation of developmental growthGO:0048639620.012
phosphorylationGO:00163102940.012
protein phosphorylationGO:00064681690.012
response to lipopolysaccharideGO:003249640.012
negative regulation of gene expressionGO:00106293870.012
positive regulation of cell cycleGO:0045787430.012
organelle fissionGO:00482853400.012
negative regulation of organelle organizationGO:0010639560.012
response to nutrient levelsGO:00316671140.012
spermatid developmentGO:0007286980.012
positive regulation of gtp catabolic processGO:0033126430.012
regulation of humoral immune responseGO:0002920510.012
heart developmentGO:0007507820.012
camera type eye developmentGO:004301040.012
gliogenesisGO:0042063800.012
ras protein signal transductionGO:0007265880.012
hematopoietic progenitor cell differentiationGO:000224410.011
axoneme assemblyGO:0035082180.011
dendrite self avoidanceGO:007059380.011
epithelial tube morphogenesisGO:0060562880.011
modification dependent macromolecule catabolic processGO:0043632790.011
regulation of epidermal growth factor receptor signaling pathwayGO:0042058420.011
positive regulation of gene expressionGO:00106282900.011
regulation of gene expression epigeneticGO:00400291280.011
negative regulation of mitotic cell cycleGO:00459301090.011
response to radiationGO:00093141550.011
small gtpase mediated signal transductionGO:0007264880.011
regulation of chromosome organizationGO:0033044640.011
mesenchymal cell differentiationGO:004876210.011
negative regulation of apoptotic processGO:0043066630.011
positive regulation of nucleotide metabolic processGO:0045981550.011
leg disc morphogenesisGO:0007478800.011
secretion by cellGO:00329401010.011
nucleoside monophosphate catabolic processGO:0009125390.011
dorsal closureGO:0007391790.011
molting cycleGO:0042303560.011
response to decreased oxygen levelsGO:0036293580.011
exocrine system developmentGO:00352721620.011
regulation of mitotic cell cycle phase transitionGO:19019901300.011
purine ribonucleoside monophosphate metabolic processGO:0009167500.011
cellular response to nitrogen compoundGO:1901699510.010
stem cell fate commitmentGO:0048865250.010
tube morphogenesisGO:00352391910.010
mitotic spindle organizationGO:00070522200.010
salivary gland morphogenesisGO:00074351450.010
positive regulation of signal transductionGO:00099672230.010
regulation of vesicle mediated transportGO:0060627590.010
regulation of synapse organizationGO:00508071100.010
digestive tract developmentGO:00485651490.010
positive regulation of purine nucleotide catabolic processGO:0033123460.010

Gie disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.035