IMP: Integrative Multi-species Prediction

Drosophila melanogaster

132 known processes

nmo (Dmel_CG7892)

nemo

(Aliases: Nemo,anon-WO0172774.138,CG7892,NEMO,clone 2.43,Dmel\CG7892,anon-WO0140519.256,anon-WO0118547.332,anon-EST:Liang-2.43,Nmo,Nlk,adk1,anon-EST:Gibbs3,adk,NEMO/NLK)

Entrez: 38890
FLYBASE: FBgn0011817
UniProtKB: Q8IQ91
UniProtKB: Q8T030

Process Predictions
Disease Predictions

nmo biological process predictions

Show only novel predictionsHighlight processes of functional analogs

Filter by process size:

Biological process	GO term ID	Process size	Probability	Func Analog Org
eye morphogenesis	GO:0048592	260	1.000
compound eye morphogenesis	GO:0001745	249	1.000
embryonic morphogenesis	GO:0048598	206	0.999	Worm
eye development	GO:0001654	323	0.998
sensory organ morphogenesis	GO:0090596	260	0.996
positive regulation of cellular biosynthetic process	GO:0031328	316	0.994
positive regulation of rna biosynthetic process	GO:1902680	266	0.992
positive regulation of macromolecule metabolic process	GO:0010604	405	0.992
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.991
epithelial cell differentiation	GO:0030855	322	0.990
compound eye development	GO:0048749	307	0.984
digestive system development	GO:0055123	149	0.981	Worm
regulation of cell differentiation	GO:0045595	302	0.980
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.976
regulation of nervous system development	GO:0051960	248	0.967
transcription from rna polymerase ii promoter	GO:0006366	368	0.963
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.962
regulation of multicellular organismal development	GO:2000026	414	0.959
negative regulation of cellular biosynthetic process	GO:0031327	277	0.954
tissue morphogenesis	GO:0048729	297	0.953
positive regulation of rna metabolic process	GO:0051254	271	0.951
spermatid differentiation	GO:0048515	114	0.950
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.946
positive regulation of transcription dna templated	GO:0045893	266	0.944
imaginal disc derived appendage development	GO:0048737	399	0.939
morphogenesis of an epithelium	GO:0002009	276	0.939
regionalization	GO:0003002	416	0.938
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.938
eye photoreceptor cell differentiation	GO:0001754	145	0.933
establishment of ommatidial planar polarity	GO:0042067	49	0.911
negative regulation of gene expression	GO:0010629	387	0.909
neuron projection guidance	GO:0097485	241	0.908
tube morphogenesis	GO:0035239	191	0.908	Worm
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.903
positive regulation of biosynthetic process	GO:0009891	316	0.896
regulation of intracellular signal transduction	GO:1902531	236	0.887	Mouse
compound eye photoreceptor cell differentiation	GO:0001751	140	0.886
dendrite development	GO:0016358	204	0.882
axon development	GO:0061564	297	0.873
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.869	Human
taxis	GO:0042330	304	0.862
negative regulation of cellular metabolic process	GO:0031324	382	0.852
columnar cuboidal epithelial cell differentiation	GO:0002065	256	0.849
renal system development	GO:0072001	72	0.840
cardiovascular system development	GO:0072358	82	0.837
actin cytoskeleton organization	GO:0030036	206	0.837
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.836
regulation of protein metabolic process	GO:0051246	256	0.835
regulation of anatomical structure morphogenesis	GO:0022603	242	0.835
synapse organization	GO:0050808	196	0.834
axon guidance	GO:0007411	233	0.817
digestive tract morphogenesis	GO:0048546	127	0.816	Worm
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.815
positive regulation of gene expression	GO:0010628	290	0.805
aggressive behavior	GO:0002118	63	0.795
localization of cell	GO:0051674	257	0.787
synapse assembly	GO:0007416	143	0.785
regulation of organ morphogenesis	GO:2000027	78	0.785
immune response	GO:0006955	246	0.781
spermatogenesis	GO:0007283	200	0.779
cellular protein modification process	GO:0006464	438	0.778
larval behavior	GO:0030537	42	0.777
segmentation	GO:0035282	207	0.773
cell migration	GO:0016477	238	0.765
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.750
immune system development	GO:0002520	57	0.742
regulation of phosphorylation	GO:0042325	147	0.741
response to gravity	GO:0009629	26	0.740
male gamete generation	GO:0048232	201	0.739
negative regulation of biosynthetic process	GO:0009890	277	0.732
spermatid development	GO:0007286	98	0.725
epithelial cell development	GO:0002064	274	0.717
photoreceptor cell differentiation	GO:0046530	170	0.707
regulation of synapse structure and activity	GO:0050803	128	0.702
dendrite morphogenesis	GO:0048813	199	0.696
head development	GO:0060322	135	0.674
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.662
regulation of gene expression epigenetic	GO:0040029	128	0.659
circulatory system development	GO:0072359	82	0.646
regulation of cell morphogenesis	GO:0022604	163	0.639
single organism behavior	GO:0044708	391	0.633
negative regulation of signal transduction	GO:0009968	206	0.627
appendage development	GO:0048736	401	0.623
regulation of neurogenesis	GO:0050767	158	0.618
gastrulation	GO:0007369	70	0.615	Worm
negative regulation of rna metabolic process	GO:0051253	251	0.615
compound eye photoreceptor development	GO:0042051	78	0.606
morphogenesis of a polarized epithelium	GO:0001738	93	0.600
negative regulation of rna biosynthetic process	GO:1902679	240	0.594
neurological system process	GO:0050877	358	0.579
dorsal closure	GO:0007391	79	0.572
hemopoiesis	GO:0030097	46	0.571
digestive tract development	GO:0048565	149	0.560	Worm
establishment of localization in cell	GO:0051649	402	0.552
hematopoietic or lymphoid organ development	GO:0048534	57	0.548
appendage morphogenesis	GO:0035107	397	0.541
actin filament based process	GO:0030029	220	0.539
protein localization	GO:0008104	284	0.537	Worm
synaptic growth at neuromuscular junction	GO:0051124	119	0.533
death	GO:0016265	284	0.523
eggshell chorion assembly	GO:0007306	66	0.521
morphogenesis of embryonic epithelium	GO:0016331	94	0.519
negative regulation of cell differentiation	GO:0045596	143	0.503
chorion containing eggshell formation	GO:0007304	105	0.503
wing disc morphogenesis	GO:0007472	344	0.501
intracellular signal transduction	GO:0035556	300	0.499	Mouse
regulation of neuron differentiation	GO:0045664	103	0.498
segment specification	GO:0007379	33	0.495
r3 r4 cell differentiation	GO:0048056	12	0.493
regulation of immune system process	GO:0002682	176	0.467
regulation of protein modification process	GO:0031399	112	0.458
dna metabolic process	GO:0006259	227	0.452
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	119	0.447
embryonic organ development	GO:0048568	50	0.441
regulation of apoptotic process	GO:0042981	130	0.434
positive regulation of molecular function	GO:0044093	136	0.434
chemotaxis	GO:0006935	249	0.433
chaeta development	GO:0022416	97	0.432
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.426
growth	GO:0040007	359	0.419
regulation of catalytic activity	GO:0050790	185	0.415
imaginal disc derived wing morphogenesis	GO:0007476	337	0.415
neuromuscular junction development	GO:0007528	149	0.408
imaginal disc derived wing vein morphogenesis	GO:0008586	44	0.405
tissue migration	GO:0090130	155	0.404
immune system process	GO:0002376	347	0.402
regulation of epithelial cell differentiation	GO:0030856	4	0.400
r7 cell differentiation	GO:0045466	43	0.400
cell motility	GO:0048870	251	0.393
negative regulation of transcription dna templated	GO:0045892	237	0.392
renal tubule development	GO:0061326	64	0.379
axonogenesis	GO:0007409	290	0.378
cell division	GO:0051301	248	0.374	Worm
inter male aggressive behavior	GO:0002121	60	0.374
epithelial tube morphogenesis	GO:0060562	88	0.372
tube development	GO:0035295	244	0.361	Worm
negative regulation of growth	GO:0045926	84	0.360
eggshell formation	GO:0030703	105	0.360
embryonic development via the syncytial blastoderm	GO:0001700	148	0.355
multi organism behavior	GO:0051705	175	0.353
regulation of response to stress	GO:0080134	200	0.342
compound eye photoreceptor fate commitment	GO:0001752	36	0.340
respiratory system development	GO:0060541	213	0.339
central nervous system development	GO:0007417	201	0.339
regulation of cell shape	GO:0008360	113	0.335
mapk cascade	GO:0000165	107	0.325	Mouse
actin filament organization	GO:0007015	126	0.325
regulation of molecular function	GO:0065009	217	0.317
mesoderm development	GO:0007498	78	0.309
regulation of synapse organization	GO:0050807	110	0.308
regulation of phosphate metabolic process	GO:0019220	210	0.297
nephron epithelium development	GO:0072009	3	0.291
muscle structure development	GO:0061061	224	0.285	Worm
sensory perception	GO:0007600	196	0.279
urogenital system development	GO:0001655	72	0.265
regulation of cell fate specification	GO:0042659	27	0.264
negative regulation of multicellular organismal process	GO:0051241	142	0.257
positive regulation of developmental process	GO:0051094	143	0.256
regulation of stem cell proliferation	GO:0072091	40	0.252
negative regulation of signaling	GO:0023057	219	0.252
regulation of cellular protein metabolic process	GO:0032268	243	0.247
biological adhesion	GO:0022610	138	0.242
eye photoreceptor cell fate commitment	GO:0042706	37	0.241
regulation of neuroblast proliferation	GO:1902692	34	0.236
protein targeting to nucleus	GO:0044744	51	0.232
establishment of tissue polarity	GO:0007164	87	0.229
positive regulation of signaling	GO:0023056	243	0.223
embryonic pattern specification	GO:0009880	174	0.220
positive regulation of response to stimulus	GO:0048584	323	0.218
regulation of protein phosphorylation	GO:0001932	64	0.216
regulation of synaptic growth at neuromuscular junction	GO:0008582	89	0.211
cellular protein localization	GO:0034613	160	0.209
columnar cuboidal epithelial cell development	GO:0002066	249	0.208
protein phosphorylation	GO:0006468	169	0.206
developmental maturation	GO:0021700	172	0.204
apoptotic process	GO:0006915	159	0.200
protein modification process	GO:0036211	438	0.200
cell fate determination	GO:0001709	91	0.191	Worm
phosphorylation	GO:0016310	294	0.189
positive regulation of cell differentiation	GO:0045597	64	0.187
cell adhesion	GO:0007155	136	0.186
establishment of planar polarity	GO:0001736	87	0.186
cellular component assembly involved in morphogenesis	GO:0010927	151	0.185
compound eye cone cell differentiation	GO:0042675	13	0.184
epithelial cell migration	GO:0010631	148	0.181
startle response	GO:0001964	16	0.179
positive regulation of signal transduction	GO:0009967	223	0.178
cellular amino acid metabolic process	GO:0006520	61	0.175
regulation of immune response	GO:0050776	118	0.174
blastoderm segmentation	GO:0007350	159	0.172
macromolecular complex assembly	GO:0065003	256	0.170
positive regulation of cellular protein metabolic process	GO:0032270	118	0.168
molting cycle chitin based cuticle	GO:0007591	56	0.167
stress activated mapk cascade	GO:0051403	52	0.165
embryonic hemopoiesis	GO:0035162	26	0.159
response to other organism	GO:0051707	293	0.158
heart development	GO:0007507	82	0.157
synaptic transmission	GO:0007268	288	0.156
positive regulation of protein metabolic process	GO:0051247	128	0.153
nephron development	GO:0072006	3	0.152
eye photoreceptor cell development	GO:0042462	81	0.150
negative regulation of response to stimulus	GO:0048585	258	0.149
photoreceptor cell development	GO:0042461	96	0.149
epidermis development	GO:0008544	65	0.148
small gtpase mediated signal transduction	GO:0007264	88	0.147
stem cell division	GO:0017145	69	0.146
formation of primary germ layer	GO:0001704	24	0.144	Worm
forebrain development	GO:0030900	2	0.142
regulation of cellular response to stress	GO:0080135	89	0.140
chromosome organization	GO:0051276	360	0.139
kidney epithelium development	GO:0072073	3	0.137
intracellular protein transport	GO:0006886	104	0.136
regulation of cellular component biogenesis	GO:0044087	201	0.135
head involution	GO:0008258	35	0.135
adult chitin containing cuticle pigmentation	GO:0048085	16	0.131
regulation of growth	GO:0040008	233	0.130
cell fate specification	GO:0001708	71	0.129	Worm
regulation of phosphorus metabolic process	GO:0051174	210	0.128
stem cell development	GO:0048864	79	0.127
protein import into nucleus	GO:0006606	51	0.124
regulation of programmed cell death	GO:0043067	152	0.124
nucleocytoplasmic transport	GO:0006913	72	0.124
establishment or maintenance of cell polarity	GO:0007163	167	0.123
cell proliferation	GO:0008283	299	0.122
regulation of cell development	GO:0060284	215	0.121
amide biosynthetic process	GO:0043604	42	0.121
positive regulation of catalytic activity	GO:0043085	118	0.121
brain morphogenesis	GO:0048854	16	0.121
negative regulation of developmental growth	GO:0048640	64	0.120
negative regulation of developmental process	GO:0051093	201	0.118
stem cell differentiation	GO:0048863	117	0.118
protein localization to nucleus	GO:0034504	55	0.118
regulation of cell cycle	GO:0051726	291	0.117
regulation of localization	GO:0032879	275	0.116
open tracheal system development	GO:0007424	204	0.115
protein transport	GO:0015031	155	0.115
epithelium migration	GO:0090132	148	0.115
larval development	GO:0002164	104	0.114	Worm
negative regulation of intracellular signal transduction	GO:1902532	57	0.114
post embryonic appendage morphogenesis	GO:0035120	385	0.114
regulation of response to biotic stimulus	GO:0002831	63	0.114
dorsal appendage formation	GO:0046843	47	0.113
positive regulation of phosphorylation	GO:0042327	87	0.112
response to biotic stimulus	GO:0009607	294	0.111
brain development	GO:0007420	120	0.109
rna processing	GO:0006396	147	0.107
catabolic process	GO:0009056	409	0.106
protein complex biogenesis	GO:0070271	201	0.106
branching involved in open tracheal system development	GO:0060446	45	0.103
muscle cell differentiation	GO:0042692	103	0.098	Worm
negative regulation of immune system process	GO:0002683	50	0.097
r3 r4 cell fate commitment	GO:0007464	10	0.096
erbb signaling pathway	GO:0038127	58	0.095
regulation of bmp signaling pathway	GO:0030510	23	0.093
cell death	GO:0008219	279	0.093
negative regulation of nervous system development	GO:0051961	92	0.093
regulation of dendrite morphogenesis	GO:0048814	28	0.093
anterior posterior pattern specification	GO:0009952	136	0.092
negative regulation of cell development	GO:0010721	62	0.092
regulation of antimicrobial humoral response	GO:0002759	50	0.091
antimicrobial peptide production	GO:0002775	46	0.091
camera type eye development	GO:0043010	4	0.089
programmed cell death	GO:0012501	257	0.088
neural precursor cell proliferation	GO:0061351	75	0.087
imaginal disc pattern formation	GO:0007447	91	0.086
hair cell differentiation	GO:0035315	47	0.084
regulation of cytoskeleton organization	GO:0051493	89	0.084
organelle assembly	GO:0070925	198	0.084
organonitrogen compound metabolic process	GO:1901564	318	0.083
response to abiotic stimulus	GO:0009628	341	0.083
regulation of antimicrobial peptide biosynthetic process	GO:0002805	38	0.082
ras protein signal transduction	GO:0007265	88	0.082
regulation of developmental growth	GO:0048638	174	0.082
wing disc dorsal ventral pattern formation	GO:0048190	47	0.082
epidermal cell differentiation	GO:0009913	51	0.081
cellular macromolecule localization	GO:0070727	220	0.081
wnt signaling pathway	GO:0016055	98	0.081
carboxylic acid metabolic process	GO:0019752	92	0.081
bmp signaling pathway	GO:0030509	27	0.079
developmental growth	GO:0048589	280	0.079
regulation of developmental pigmentation	GO:0048070	24	0.078
regulation of notch signaling pathway	GO:0008593	100	0.078
establishment of protein localization	GO:0045184	163	0.077
positive regulation of neural precursor cell proliferation	GO:2000179	8	0.077
signal transduction by phosphorylation	GO:0023014	107	0.076	Mouse
blood circulation	GO:0008015	26	0.075
ovarian follicle cell development	GO:0030707	248	0.075
stem cell proliferation	GO:0072089	88	0.074
compound eye cone cell fate commitment	GO:0042676	5	0.074
cellular response to dna damage stimulus	GO:0006974	223	0.074
stress activated protein kinase signaling cascade	GO:0031098	55	0.074
positive regulation of synaptic growth at neuromuscular junction	GO:0045887	26	0.073
posttranscriptional regulation of gene expression	GO:0010608	145	0.072
single organism nuclear import	GO:1902593	51	0.071
lateral inhibition	GO:0046331	206	0.070
negative regulation of protein metabolic process	GO:0051248	85	0.070
telencephalon development	GO:0021537	2	0.070
feeding behavior	GO:0007631	50	0.068
skin development	GO:0043588	65	0.068
positive regulation of neuroblast proliferation	GO:0002052	7	0.065
endodermal cell fate commitment	GO:0001711	3	0.065	Worm
endocytosis	GO:0006897	310	0.064
apoptotic signaling pathway	GO:0097190	27	0.064
neuroblast fate commitment	GO:0014017	19	0.063
regulation of transport	GO:0051049	181	0.062
regulation of protein transport	GO:0051223	57	0.061
positive regulation of cellular amine metabolic process	GO:0033240	0	0.061
neuroblast proliferation	GO:0007405	74	0.060
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.058
negative regulation of programmed cell death	GO:0043069	72	0.058
positive regulation of protein modification process	GO:0031401	58	0.057
axis specification	GO:0009798	167	0.057	Worm
regulation of organelle organization	GO:0033043	196	0.056
positive regulation of protein phosphorylation	GO:0001934	34	0.056
purine nucleotide metabolic process	GO:0006163	146	0.055
negative regulation of synaptic growth at neuromuscular junction	GO:0045886	39	0.055
positive regulation of phosphorus metabolic process	GO:0010562	139	0.055
somatic stem cell division	GO:0048103	37	0.055
cellular ketone metabolic process	GO:0042180	24	0.055
innate immune response	GO:0045087	144	0.054
humoral immune response	GO:0006959	117	0.053
regulation of response to external stimulus	GO:0032101	115	0.052
amine metabolic process	GO:0009308	12	0.051
regulation of cell death	GO:0010941	173	0.051
peptidyl tyrosine phosphorylation	GO:0018108	24	0.051
regulation of mapk cascade	GO:0043408	92	0.050
rhabdomere development	GO:0042052	38	0.050
positive regulation of phosphate metabolic process	GO:0045937	139	0.050
cardiac cell fate commitment	GO:0060911	17	0.050
negative regulation of epidermal growth factor receptor signaling pathway	GO:0042059	29	0.049
chitin based cuticle development	GO:0040003	49	0.049
morphogenesis of a branching epithelium	GO:0061138	45	0.048
circadian rhythm	GO:0007623	105	0.048
defense response	GO:0006952	300	0.048
response to external biotic stimulus	GO:0043207	293	0.048
regulation of cellular localization	GO:0060341	136	0.048
cuticle pattern formation	GO:0035017	27	0.047
adult behavior	GO:0030534	137	0.047
jnk cascade	GO:0007254	50	0.047
peptidyl amino acid modification	GO:0018193	105	0.047	Mouse
branching morphogenesis of an epithelial tube	GO:0048754	45	0.046
response to alcohol	GO:0097305	95	0.046
regulation of peptidase activity	GO:0052547	39	0.046
mushroom body development	GO:0016319	70	0.046
regulation of compound eye cone cell fate specification	GO:0042682	4	0.045
myotube differentiation	GO:0014902	46	0.044
establishment of spindle orientation	GO:0051294	18	0.044
negative regulation of molecular function	GO:0044092	51	0.044
regulation of hydrolase activity	GO:0051336	97	0.044
protein import	GO:0017038	55	0.044
positive regulation of neurogenesis	GO:0050769	41	0.044
epidermal growth factor receptor signaling pathway	GO:0007173	58	0.043
regulation of glial cell proliferation	GO:0060251	11	0.043
organonitrogen compound biosynthetic process	GO:1901566	117	0.042
positive regulation of immune system process	GO:0002684	68	0.041
spindle localization	GO:0051653	22	0.041
regulation of cellular amide metabolic process	GO:0034248	39	0.041
oocyte axis specification	GO:0007309	108	0.041
nuclear import	GO:0051170	51	0.041
cell maturation	GO:0048469	144	0.041
immune effector process	GO:0002252	98	0.040
tracheal outgrowth open tracheal system	GO:0007426	18	0.040
purine ribonucleoside catabolic process	GO:0046130	112	0.040
negative regulation of wnt signaling pathway	GO:0030178	28	0.040
centrosome cycle	GO:0007098	137	0.039
negative regulation of cell death	GO:0060548	81	0.039
muscle cell development	GO:0055001	50	0.039
connective tissue development	GO:0061448	3	0.039
oocyte microtubule cytoskeleton organization	GO:0016325	35	0.038
nephron tubule morphogenesis	GO:0072078	3	0.038
peptide biosynthetic process	GO:0043043	42	0.038
intrinsic apoptotic signaling pathway	GO:0097193	16	0.038
regulation of cell cycle process	GO:0010564	181	0.038
negative regulation of transferase activity	GO:0051348	18	0.037
response to wounding	GO:0009611	94	0.037
establishment of organelle localization	GO:0051656	122	0.037
production of molecular mediator of immune response	GO:0002440	46	0.036
regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090092	38	0.036
regulation of antimicrobial peptide production	GO:0002784	44	0.036
regulation of immune effector process	GO:0002697	52	0.036
cellular amine metabolic process	GO:0044106	12	0.035
regulation of protein kinase activity	GO:0045859	51	0.035
positive regulation of intracellular signal transduction	GO:1902533	116	0.035
cuticle development	GO:0042335	86	0.035
hindbrain development	GO:0030902	2	0.035
regulation of cell proliferation	GO:0042127	163	0.035
malpighian tubule development	GO:0072002	64	0.034
wing disc pattern formation	GO:0035222	66	0.034
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	116	0.033
neuroblast division	GO:0055057	35	0.033
cellular amide metabolic process	GO:0043603	80	0.033
negative regulation of neurogenesis	GO:0050768	53	0.033
single organism cellular localization	GO:1902580	180	0.033
regulation of kinase activity	GO:0043549	53	0.033
cell projection assembly	GO:0030031	94	0.032
regulation of defense response	GO:0031347	102	0.032
regulation of wnt signaling pathway	GO:0030111	68	0.032
protein acylation	GO:0043543	42	0.032
regulation of cellular amine metabolic process	GO:0033238	3	0.032
eye antennal disc development	GO:0035214	60	0.032
mitotic spindle organization	GO:0007052	220	0.032	Worm
macromolecule catabolic process	GO:0009057	161	0.031
regulation of jnk cascade	GO:0046328	40	0.031
response to decreased oxygen levels	GO:0036293	58	0.031
homeostatic process	GO:0042592	199	0.031
establishment or maintenance of monopolar cell polarity	GO:0061339	15	0.031
positive regulation of cellular component organization	GO:0051130	156	0.031
muscle organ development	GO:0007517	127	0.031
negative regulation of fibroblast growth factor receptor signaling pathway	GO:0040037	2	0.031
regulation of stress activated mapk cascade	GO:0032872	41	0.030
nephron epithelium morphogenesis	GO:0072088	3	0.030
establishment or maintenance of bipolar cell polarity	GO:0061245	34	0.030
phagocytosis	GO:0006909	215	0.030
small molecule metabolic process	GO:0044281	305	0.030
segment polarity determination	GO:0007367	25	0.030
protein complex assembly	GO:0006461	200	0.030
cellular nitrogen compound catabolic process	GO:0044270	165	0.029
regulation of histone deacetylation	GO:0031063	2	0.029
response to organic cyclic compound	GO:0014070	89	0.029
organic acid metabolic process	GO:0006082	103	0.029
nuclear transport	GO:0051169	72	0.029
neuronal stem cell maintenance	GO:0097150	4	0.029
retina morphogenesis in camera type eye	GO:0060042	2	0.029
peptide metabolic process	GO:0006518	80	0.029
regulation of phosphatase activity	GO:0010921	3	0.028
positive regulation of transferase activity	GO:0051347	26	0.028
response to bacterium	GO:0009617	198	0.028
notch signaling pathway	GO:0007219	120	0.028
regulation of cytoplasmic transport	GO:1903649	47	0.028
striated muscle cell development	GO:0055002	50	0.028
fusion cell fate specification	GO:0035156	4	0.027
negative regulation of apoptotic process	GO:0043066	63	0.027
regulation of production of molecular mediator of immune response	GO:0002700	44	0.027
negative regulation of cell communication	GO:0010648	223	0.027
asymmetric stem cell division	GO:0098722	49	0.027
retina development in camera type eye	GO:0060041	4	0.027
gravitaxis	GO:0042332	26	0.027
gland development	GO:0048732	191	0.027
positive regulation of stem cell proliferation	GO:2000648	8	0.027
regulation of endopeptidase activity	GO:0052548	36	0.026
regulation of protein localization	GO:0032880	76	0.026
signal transduction in response to dna damage	GO:0042770	3	0.026
regulation of proteolysis	GO:0030162	87	0.026
posttranscriptional gene silencing	GO:0016441	46	0.026
regulation of cellular amino acid metabolic process	GO:0006521	0	0.026
nucleoside metabolic process	GO:0009116	127	0.025
stem cell maintenance	GO:0019827	67	0.025
hindgut morphogenesis	GO:0007442	58	0.025
protein targeting	GO:0006605	64	0.025
positive regulation of cellular amino acid metabolic process	GO:0045764	0	0.025
golgi organization	GO:0007030	66	0.025
ribonucleoside metabolic process	GO:0009119	127	0.025
antimicrobial peptide biosynthetic process	GO:0002777	38	0.024
r1 r6 cell differentiation	GO:0048052	4	0.024
heart contraction	GO:0060047	26	0.024
regulation of protein localization to nucleus	GO:1900180	29	0.024
neuron fate commitment	GO:0048663	50	0.024
regulation of epidermal growth factor receptor signaling pathway	GO:0042058	42	0.024
nucleobase containing compound catabolic process	GO:0034655	165	0.024
regulation of erbb signaling pathway	GO:1901184	42	0.024
regulation of embryonic development	GO:0045995	68	0.024
response to lipopolysaccharide	GO:0032496	4	0.023
ribose phosphate metabolic process	GO:0019693	145	0.023
regulation of map kinase activity	GO:0043405	17	0.023
erk1 and erk2 cascade	GO:0070371	39	0.023
actomyosin structure organization	GO:0031032	56	0.023
stem cell fate commitment	GO:0048865	25	0.023
regulation of multi organism process	GO:0043900	131	0.023
positive regulation of nervous system development	GO:0051962	69	0.022
regulation of stem cell differentiation	GO:2000736	14	0.022
anterior posterior axis specification	GO:0009948	109	0.022
regulation of neural precursor cell proliferation	GO:2000177	35	0.022
neuroblast differentiation	GO:0014016	29	0.022
cell cell signaling involved in cell fate commitment	GO:0045168	210	0.022
positive regulation of cell proliferation	GO:0008284	47	0.022
actin filament based movement	GO:0030048	26	0.022
convergent extension involved in gastrulation	GO:0060027	2	0.022
positive regulation of antimicrobial peptide biosynthetic process	GO:0002807	26	0.022
extracellular structure organization	GO:0043062	46	0.022
morphogenesis of a branching structure	GO:0001763	45	0.021
imaginal disc derived wing vein specification	GO:0007474	48	0.021
secretion	GO:0046903	109	0.021
regulation of transferase activity	GO:0051338	58	0.021
regulation of intracellular protein transport	GO:0033157	46	0.021
protein localization to organelle	GO:0033365	82	0.021
oocyte differentiation	GO:0009994	145	0.021
imaginal disc growth	GO:0007446	37	0.021
response to endogenous stimulus	GO:0009719	119	0.021	Human
oxoacid metabolic process	GO:0043436	103	0.021
mesoderm morphogenesis	GO:0048332	22	0.021
purine nucleoside triphosphate metabolic process	GO:0009144	119	0.021

nmo disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.105
nervous system disease	DOID:863	0.031
neurodegenerative disease	DOID:1289	0.031
central nervous system disease	DOID:331	0.031
motor neuron disease	DOID:231	0.031

Loading network...

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network